The area around the second lowest value of /θ_E on chromosome 3. Vertical bars represent the values for a 100-kb window positioned at their midpoint. (A) Plotted is /θ_E, whereas the expected value is either under a neutral or a background selection model, whatever was more conservative. The colors of the bars indicate whether /θ_E lie outside of a 95%, 96%, etc., confidence interval obtained through simulations. (B) Pink triangles mark recombination hotspots; blue lines correspond to genes from the RefSeq gene track of the UCSC genome browser. The closest gene is EPHA6. (C–E) The values for , human–chimpanzee divergence, and the recombination rate in cM/Mb are plotted.