Table 1.

Monogenic mutations mapped using the SNP panel

Mutant
Mode of inheritance
Genetic backgroundsa
Mb interval
No. of affecteds
cincinnati Recessive B6, C3H/HeJ, 129X1 17 15
mummy Recessive B6, A/J 21 10
Chastity Dominant B6, C3H/HeJ, 129S6 21 9
line 11 Recessive B6, FVB 23 11
ND15 Recessive B6, FVB 25 7
ND3 Recessive B6, FVB 25 11
ND21 Recessive B6, FVB 27 10
ND94 Recessive B6, FVB 28 4
pewter-C3Hb Recessive B6, C3Heb/FeJ 28 6
hyft Recessive A/J, FVB, B6 34 12
fe1 Recessive 129S6, CAST/Ei 39 10
tiresias Recessive B6, DBA 43 9
Bigfoot Dominant 129S6, B6, DBA 43 12
peewee Recessive NAW/W1, B6, C3H/HeJ, CAST/Ei 43 15
dill-C3Hb Recessive B6, C3Heb/FeJ 45 3
bha Recessive B6, CAST/Ei, 129S6 49 11
ND58 Recessive B6, FVB 55 4
Bx708 Dominant B6, DBA 55 11
chaos4 Recessive B6, C3Heb/FeJ 57 4
20884 Recessive B6, FVB 57 5
dill-FVBb Recessive B6, FVB 70 5
baldy Recessive B6, FVB 73 9
pewter-FVBb Recessive B6, FVB 78 5
ND24 Recessive B6, FVB 83 4
Average
43.3
8.4

a B6 (C57BL/6J); 129X1 (129X1/SvJ); 129S6 (129S6/SvEvTac); FVB (FVB/NJ); DBA (DBA/2J).

b pewter and dill mutants each were mapped by using two genetic crosses.