Accuracy in classifications of variants assayed in four mutagenesis experiments
Positive vs. deleterious | Intermediate vs. negative | |||||
|---|---|---|---|---|---|---|
| MAPP | SIFT | Increase | MAPP | |||
| HIV protease | 80.4% | 78.6% | 1.8% | 76.7% | ||
| LacI | 69.2% | 67.9% | 1.3% | 74.5% | ||
| HIV RT | 64.1% | 55.0% | 9.1% | 72.9% | ||
| T4 lysozyme | 73.0% | 68.3% | 4.7% | 62.6% | ||