Performance of Ab Initio Programs on Burset/Guigo (1996) Data Set on Adding Similarity Information
Nucleotide level | Exon level | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Program | No. genes | SEN | SPE | AC | CC | CR | PC | OL | ME | WE | ESEN | ESPE | EAVG | ||||||||||
| GENSCAN | 8 | 0.93 | 0.91 | 0.92 | 0.90 | 2156 | 264 | 26 | 203 | 188 | 0.78 | 0.79 | 0.79 | ||||||||||
| GENSCAN+BLASTX | 0 | 0.98 | 0.91 | 0.94 | 0.93 | 2299 | 230 | 28 | 100 | 305 | 0.84 | 0.80 | 0.82 | ||||||||||
| GENSCAN+BLASTX+BLASTN | 0 | 0.98 | 0.93 | 0.94 | 0.94 | 2301 | 222 | 22 | 112 | 250 | 0.84 | 0.82 | 0.83 | ||||||||||
| HMMgene | 38 | 0.87 | 0.88 | 0.91 | 0.86 | 2092 | 239 | 21 | 308 | 139 | 0.76 | 0.77 | 0.77 | ||||||||||
| HMMgene+BLASTX | 2 | 0.95 | 0.95 | 0.94 | 0.94 | 2256 | 248 | 21 | 135 | 144 | 0.83 | 0.83 | 0.83 | ||||||||||
| HMMgene+BLASTX+BLASTN | 2 | 0.95 | 0.96 | 0.95 | 0.94 | 2252 | 234 | 17 | 154 | 97 | 0.83 | 0.84 | 0.84 | ||||||||||
| EUI | 20 | 0.90 | 0.92 | 0.93 | 0.90 | 2214 | 176 | 12 | 250 | 98 | 0.80 | 0.84 | 0.82 | ||||||||||
| EUI+BLASTX | 0 | 0.96 | 0.96 | 0.95 | 0.95 | 2297 | 213 | 14 | 129 | 106 | 0.84 | 0.86 | 0.85 | ||||||||||
| EUI+BLASTX+BLASTN | 0 | 0.96 | 0.97 | 0.95 | 0.95 | 2294 | 205 | 12 | 142 | 79 | 0.84 | 0.87 | 0.85 | ||||||||||
| EUI-FRAME | 27 | 0.88 | 0.92 | 0.92 | 0.88 | 2188 | 167 | 11 | 286 | 87 | 0.79 | 0.84 | 0.81 | ||||||||||
| EUI-FRAME+BLASTX | 1 | 0.96 | 0.96 | 0.95 | 0.95 | 2286 | 214 | 13 | 140 | 95 | 0.84 | 0.86 | 0.85 | ||||||||||
| EUI-FRAME+BLASTX+BLASTN | 1 | 0.95 | 0.97 | 95.00 | 0.90 | 2283 | 206 | 12 | 152 | 69 | 0.83 | 0.87 | 0.85 | ||||||||||
| GI | 43 | 0.84 | 0.90 | 0.91 | 0.85 | 2118 | 138 | 8 | 387 | 67 | 0.76 | 0.83 | 0.80 | ||||||||||
| GI+BLASTX | 2 | 0.95 | 0.97 | 0.95 | 0.95 | 2277 | 195 | 10 | 167 | 76 | 0.83 | 0.87 | 0.85 | ||||||||||
| GI+BLASTX+BLASTN | 2 | 0.94 | 0.97 | 0.94 | 0.94 | 2274 | 190 | 9 | 178 | 52 | 0.83 | 0.88 | 0.85 | ||||||||||
| GENOMESCAN | 12 | 0.95 | 0.89 | 0.92 | 0.90 | 2245 | 235 | 45 | 130 | 350 | 0.81 | 0.78 | 0.80 | ||||||||||