ABCB1 Haplotypes for High-Frequency Loci Between IVS 6+139 and IVS 26+1684
Id | Haplotypea | Freqb | Nb |
|---|---|---|---|
| 1 | TGTTTTCC | 0.35 | 34 |
| 2 | CACCGTCC | 0.11 | 11 |
| 3 | CACCGCTT | 0.12 | 12 |
| 4 | CACCGCCC | 0.15 | 14 |
| 5 | CACTTTCC | 0.05 | 5 |
| 6 | TGTTTCTT | 0.03 | 3 |
| 7 | TGCTTTCC | 0.03 | 3 |
| 8 | TGTTGCTT | 0.03 | 3 |
| Ancestral | CACCGCTC |
a Derived by EM inference from CEPH trio data on the following eight loci (details in Table 1): IVS 6+139 C>T, IVS 6+251 A>G, 1236C>T, IVS 16+73 G>A, 2677G>T,A, 3435C>T, IVS 26+1573 T>C, IVS 26+1684 C>T.
b Haplotype numbers and frequencies are relative to parental chromosomes only. The 3435C>T variant is bold underlined.