Table 6.

Local Similarity in Nonsynonymous Substitution Rate KA, Including All Genes or Excluding Duplicate Genes



Human—mouse

Mouse—rat

ρ
P
N
ρ
P
N
All genes 0.126 <0.0001 4596 0.055 0.0018 4116
Nonduplicatesa
0.065
0.0002
4515
0.022
0.087
3995

a Genes were excluded from the focal average if they exhibited significant sequence similarity to the focal gene (BLAST expectation value E <0.02; Lercher et al. 2001).