Table 1.

Genomic Estimates of Local Similarity in Evolutionary Rates, Assayed by the Focal Average Correlation ρ

Human-mouse
Mouse-rat
ρa
pb
N
ρa
pb
N
All genes
    KA 0.126 <0.0001 4596 0.055 0.0018 4116
    K4 0.334 <0.0001 4284 0.183 <0.0001 3909
    [TeX:] \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(K_{4}^{\mathrm{excCpG}}\) \end{document} 0.251 <0.0001 4178 0.179 <0.0001 3815
    Ki — — — 0.170 <0.0001 541
    Kindel — — — 0.191 <0.0001 541
Nondisparate genes
    KA 0.103 0.0003 1568 0.065 0.0010 3554
    K4 0.272 <0.0001 1377 0.166 <0.0001 3380
    [TeX:] \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(K_{4}^{\mathrm{excCpG}}\) \end{document} 0.189 <0.0001 1292 0.173 0.0002 3298
    Ki — — — 0.151 0.0016 469
    Kindel
—
—
—
0.160
0.0004
469

a Focal average correlation = correlation coefficient for data pairs, each consisting of a gene's rate K and the mean of its neighbors within 1 Mb.

b Number of equal or higher ρ values found in 10,000 randomly rearranged genomes.