Table 4.

Replication of Linkage Region in a Family With a Combination of Chronic Mucocutaneous–Candidiasis and Thyroid Disease, Using SNPs

Informative markers on Chr 2
LOD score
P-value
Interval
10 cM STR genome scan 28 4.21 0.0039 35.28 cM
SNP array (11,555 SNPs)
525
8.39
0.0078
17.73 cM

[i] Nonparametric LOD (NPL) scores were calculated using GENEHUNTER on the 28 STR markers and 525 SNPs on chromosome 2.