Mouse/Rat Rearrangement Breakpoints on the Human Genomea
M-Inter R-Inter | M-Intra R-Intra | M-Inter R-Intra | M-Intra R-Inter | M-Inter | R-Inter | M-Intra | R-Intra |
|---|---|---|---|---|---|---|---|
| 130b | 125b | 6 | 5 | 14c | 1d | 21e | 46f |
a All breakpoints identified are incorporated. M-Inter R-Inter: shared interchromosomal breakpoints. M-Intra R-Intra: shared intrachromosomal breakpoints. M-Inter R-Intra: shared breakpoints, interchromosomal for mouse and intrachromosomal for rat. M-Inter: mouse-specific interchromosomal breakpoints.
b About 58 are due to human specific intrachromosomal rearrangements.
c All 14 breakpoints are described in details in Table 3.
d R15/R16 fission, the only exception for the mouse fissions described in Table 3.
e Eight are associated with M-Inter (mouse fission related inversions) as described in Table 3, involving syntenic blocks of >100 kb and with >3 BACs.
f A total of 14 are due to inversions in R1p, R11, R19, R20, R10/M11/H17 as described in Table 4, involving synteny blocks of >100 kb and with >3 BACs; 30 involve simple inversions in the middle of the human/mouse syntenic blocks.