Scatter diagrams of output scores obtained with SignalP v2.0 for (A) 142 putative extracellular proteins identified from P. infestans using PexFinder, and (B) 59 known and annotated oomycete proteins. “HMM score”: The prediction score obtained with the SignalP V2.0 hidden Markov model program. “Mean S score”: The score obtained with the SignalP V2.0 neural network program. Scores for both programs range from 0 to 1, with higher scores indicating a higher probability for a signal peptide. Sequences predicted to correspond to extracellular proteins based on annotation using the InterPro database (Apweiler et al. 2001), GenBank (Karsch-Mizrachi and Ouellette 2001), or literature review are shown as black boxes, and other sequences are shown as gray boxes.