Table 4.

Top 20 InterPro Domains and SCOP Superfamily Hits for the Mouse Secretome


InterPro Domains
Domain
No.
Description
IPR000561 103 EGF-like domain
IPR001254 101 Serine protease, trypsin family
IPR001314 97 Chymotrypsin serine protease, family S1
IPR003599 63 Immunoglobulin subtype
IPR003006 60 Immunoglobulin/major histocompatibility complex
IPR001687 57 ATP/GTP-binding site motif A (P-loop)
IPR001881 54 EGF-like calcium-binding
IPR000087 53 Collagen triple helix repeat
IPR000152 42 Aspartic acid and asparagine hydroxylation site
IPR000379 41 Esterase/lipase/thioesterase, active site
IPR001611 31 Leucine-rich repeat
IPR001811 31 Small chemokine, interleukin-8-like
IPR001839 31 Transforming growth factor beta (TGFb)
IPR003598 31 Immunoglobulin C-2 type
IPR001128 30 Cytochrome P450
IPR003591 29 Leucine-rich repeat, typical subtype
IPR000130 26 Neutral zinc metallopeptidase
IPR000884 25 Thrombospondin, type I
IPR001304 25 C-type lectin
IPR001438
25
Type II EGF-like signature
SCOP Superfamilies
Domain
No.
Description
50494 98 Trypsin-like serine proteases
57196 90 EGF/laminin
48726 87 Immunoglobulin
47266 52 4-helical cytokines
57501 51 Cystine-knot cytokines
53474 46 alpha/beta-Hydrolases
52540 34 P-loop containing nucleotide triphosphate hydrolases
49899 33 Concanavalin A-like lectins/glucanases
56436 33 C-type lectin-like
54117 31 Interleukin 8-like chemokines
48264 29 Cytochrome P450
55486 26 Metalloproteases (zincins), catalytic domain
53300 24 Integrin A (or I) domain
50814 23 Lipocalins
53448 23 Nucleotide-diphospho-sugar transferases
57392 23 Defensin-like
57467 23 Ovomucoid/PCI-1 like inhibitors
54001 23 Cysteine proteinases
57535 22 Complement control module/SCR domain
49842
21
TNF-like