Table 1.

Statistical Significance of the Intron Excess in Module Boundaries




Number of introns

Average excess (15-30 Å)

p-value
Set 1 3328 4.3%
Set 2 550 10.8% 0.025
Set 3 118 23.4% 0.0044
Set 4
29
68.0%
0.00001

[i] The sets were scored by averaging the excess of introns in the boundary regions, compared to the random expectation, for modules of diameters from 15 to 30 Å. The p values were estimated by drawing 10,000 (100,000 for set 4) random subsets from set 1 and asking how many have equal or greater average excesses.