Table 5.

Effects of Stringency of TF Sites on Specificity

Stringency Sensitivity Model 1 Model 2
High42%14/154/4
Medium61%2/52/5
Low71%0/71/10

[i] High stringency is the original model I and II, as in the above analyses. In medium stringency, we lower the matrix cutoff scores to NF-κB, 0.95; AP1, 0.95; IK1, 0.94; STAT, 0.91; IK3, IRF1, IRF2, ISRE, 0.86. Low stringency sets the matrix cutoff scores to NF-κB, 0.92; AP1, 0.95; IK1, 0.94; STAT, 0.91; IK3, IRF1, IRF2, ISRE, 0.86. As we lower the matrix cutoffs, only the additional predictions are shown in the table.