Gene clusters related to V. vulnificus pathogenicity. (A) Capsular polysaccharide, (B) siderophore biosynthesis and transport, (C) heme receptor and transport, (D) RTX. The diagrams (not to scale) depict the gene clusters and paralogous members in V. vulnificus YJ016 and the corresponding segments and genes in V. cholerae El Tor N16961. VV1, the large chromosome of V. vulnificus; VV2, the small chromosome of V. vulnificus; VC1, the large chromosome of V. cholerae; VC2, the small chromosome of V. cholerae. Unless specifically given, gene names for V. cholerae are used to indicate the corresponding loci in the V. vulnificus genome. (#) E. coli gene name, (♦) low homology to E. coli gene, (†) V. vulnificus gene name, (^*) two ORFs.