Table 1.

Correlation (R) Between the Propensity for Gene Loss, Substitution Rates, Gene Expression Level, and the Number of Protein-Protein Interactions




Expression in


PGL
Yeast
Worm
Human
Interactions in yeast
PGL N/A −0.179 −0.120 −0.202 −0.341
P-distance a 0.336 −0.312 −0.260 −0.359 −0.188
PAM (average from A.t.) b 0.368 −0.164 −0.133 −0.204 −0.169
JTT (average from A.t.) 0.317 −0.271 −0.226 −0.299 −0.178
JTT (three-kingdom average) 0.403 −0.286 −0.227 −0.311 −0.213
JTT (average from A.t., γ-corrected)
0.300
−0.230
−0.198
−0.263
−0.165

a Different method for evolutionary distance (a surrogate for substitution rate) calculation are introduced in Methods.

b A.t., Arabidopsis thaliana.