Markup | Genome Research

Table 4.

Permutation Tests of Significance of the Contribution to a Multitrait LOD Score of Individual Measures

	Chr 1		Chr 3		Chr 5		Chr 6
Shuttle box Avoidances	0.662		0.888		0.021	0.000	0.561
Fear conditioning Cue	0.800		0.731		0.121	0.000	0.732
Context	0.682		0.661		0.228	0.002	0.790
Elevated plus maze Pct open arm time	0.552		0.551		0.203	0.000	0.832
Closed arm entries	0.202		0.981		0.711		0.411
Open field Activity in periphery	0.842		0.222	0.000	0.129	0.000	0.953
Activity in center	0.732		0.718		0.841		0.289
Acoustic startle response	0.478		0.732		0.879		0.154
Spontaneous activity	0.017	0.030	0.863		0.861		0.014	0.000
Grooming	0.427		0.232		0.093	0.000	0.143
Rearing	0.000	0.000	0.920		0.678		0.920
Defecation	0.118		0.000	0.000	0.456		0.000	0.000
	Chr 10		Chr 15		Chr 19		Chr X
Shuttle box Avoidances	0.000	0.000	0.747		0.765		0.621
Fear conditioning Cue	0.471		0.562		0.881		0.881
Context	0.555	0.000	0.444		0.831		0.923
Elevated plus maze Pct open arm time	0.647		0.447		0.518		0.921
Closed arm entries	0.522		0.161		0.759		0.929
Open field Activity in periphery	0.059		0.645		0.800		0.038	0.000
Activity in center	0.133		0.060	0.021	0.561		0.677
Acoustic startle response	0.027	0.000	0.412	0.011	0.627		0.621
Spontaneous activity	0.237		0.761		0.929		0.510	0.019
Grooming	0.521		0.000	0.000	0.033	0.000	1.000
Rearing	0.242	0.012	0.145		0.666		0.321
Defecation	0.027	0.000	0.432		0.479		0.000	0.000

[i] Two columns are shown for each quantitative trait loci. In the first, the probabilities of the contribution when all measures are included in the analysis are shown. The second displays the probabilities after all nonsignificant contributors have been excluded in stepwise fashion, as explained in the text. The results are based on 10,000 permutations.