Table 1.

Methylated CpG Islands Characterized in Detail

Clone ID Methylation pattern Chromosomal location Associated genes
Accession no. Predicted function
3-10SMR1q4414042537[ii] Similar to Zn finger protein
14423768Olfactory receptor 2T1
hCG1644736Similar to olfactory receptor 2T1
hCG1724357Similar to olfactory receptor 2T1
3-20SMR2q365174481[ii] Histone deacetylase A
hCG1651464
hCG1656118
hCG1651461
hCG1651466
1-19SMR4p163777583[ii] WFS1 (wolframin)
1-41SMR4q35hCG1788598[ii] Similar to mouse pair-rule gene ODZ3
hCG1793025[ii] Hypothetical protein
hCG1787540Similar to mouse pair-rule gene ODZ3
4-8SMR4q35hCG1788598[ii] Adjacent to but distinct from 1-41
3-4gDMR6q24hCG1660630[ii] HYMA1
4-7SMR7p226806913[ii] Centaurin-α
hCG1747708
hCG1790856
hCG1747710Cytochrome P450 homolog
1-30SMR7q11.1hCG1779529[ii] Rab5 exchange factor homolog
hCG1779527Antisense to hCG1779529
hCG1789113Antisense to hCG1779529
1364287260S ribosomal prot L35
6572672Putative transcription factor
1-22SMR7q3611386149[ii] Tyrosine phosphatase
hCG1799787BHLF1 protein
3-2SMR8p23hCG1659058[ii] Proline-rich mucin homolog
2-5gDMR8q21.217451956Similar to antigen GOR
hCG1757665
2-48gDMR9p13hCG1659616
1-20gDMR10q2613325182[ii]
hCG1799063
3-12SMR10q263122245[ii] Inositol triphosphate phosphatase
hCG1654478
3-30gDMR11q2517456499[ii] Hypothetical gene
hCG37607
hCG1745526Hypothetical protein
1-5SMR13q34hCG20146[ii]
1-21gDMR14q328393715[ii] Heptacellular cancer candidate
hCG21408Similar to DrosophilaCLIP-190
2-42gDMR16p13.1hCG15669[ii] Ser/Thr protein kinase
3-110SMR17q258400736[ii] β-tubulin cofactor D
10435982
2-1SMR17q251655842[ii] Sulfamidase
14149793Coiled-coil protein
1-12SMR17q25hCG1806389
hCG1796817
2-78gDMR18q2113645769[ii] Elongin A3
3-8gDMR18q2113645769[ii] Adjacent to but distinct from 2-78
2-3SMR18q236912444Voltage-dependent K+ channel
1914872Choline-binding protein
5326898RNA Polymerase II CTD phosphatase
1-13gDMR18q23hCG1651089[ii]
6688241SALL3 Spalt-like zinc finger protein
hCG20372ATPase
1651088Mucin1 precursor
1-6gDMR19p13.114249150[ii] Hypothetical protein
4-3SMR19p13.39665054[ii] Ser/Thr kinase 11
hCG23965Ankyrin repeat protein
4506715Ribosomal protein S28
hCG1794585
10732648Angiopoietin-like protein
1-2SMR19q13.412053197Zinc finger protein
4505329NSF attachment protein
5901994Kaptin-actin binding protein
5689511Na/Ca exchanger protein
7657128Glioma tumor suppressor candidate
7657054EH-Domain containing protein
7657130Glioma tumor suppressor candidate
2-4gDMR20q1217484155[ii] Nuclear factor of activated T-cells 2
hCG1800975
hCG1653833
13378306Brain RPTmam4 isoform
110743Neurofilament triplet H protein
7799072DNA helicase

[i] Accession numbers correspond to GenBank entries, within 10 kb of the CpG island, unless there is no GenBank entry, in which case they correspond to Celera entries. One additional SMR could not be mapped.

[ii] CpG island lies within the transcript.