Table 3.

Reaction Subsets for Lysine Synthesis in H. pylori

1ASPB1, METL1, ASD, DAPA, DAPB, DAPD, DAPC, DAPE, DAPF, LYSA, MAEB, MDH, OOR, ALATP, SUCTP, FRDO, ATPA, NH3TP, ALAxt, NH3xt, SUCCxt, LYS
2SDAA, SERA, SERC, SERB
3PUTA1, PROC
4PUTA2, ORNTRSN, ROCF, ARGTP, UREASE, ARGxt
5DADA, ALR
6ASNA, ANSB
7PGI, FBP, FBA, TPI, GAP, PGK, PGL
8PGM, ENO, PPSA
9GND, RPI, RPE, TAL, TKTA1, TKTA2
10EDD, EDA
11GLTA, ACNB, ICD
12POR, FLDO
13CDSA, CDH, CMKA, NDK3
14GUAB, GUAA, GUAC
15NDK5, TMK2, DUT
16PTA, ACKA
17ACTP, ACxt
18PROTP1, NATP
19LACTP, DLD, LACxt
20BC1O, O2TP, O2xt
21CO2TP, CO2xt

[i] Each of the reactions subsets are correlated in the extreme pathways that correspond to lysine production in H. pylori.For example, in every extreme pathway, the reactions SDAA, SERA, SERC, SERB (group 2) are either used together or not used at all.