Table 2.

Protein-Protein Interaction Pairs Between Large Proteins

Bait Description Prey Description
KIAA0319KIAA0396(2)[i] FEM-1-like death receptor-binding protein
KIAA1299(1)SH2-B β-signaling protein
KIAA0343KIAA0417(2)
KIAA1251(1)Trabeculin-α
KIAA1634(6)Membrane-associated guanylate kinease-related MAGI-3
KIAA0348Synaptojanin 2KIAA1256(3)Intersectin 2 (SH3D1B)
KIAA0358MAP kinase-activating death domain proteinKIAA0453(1)
KIAA0364Immunoglobulin-like domain-containing 1 proteinKIAA1131(1)
KIAA1464(1)RanBPM homolog (66%)[ii]
KIAA0387Protein-tyrosine phosphatase X precursorKIAA0097(2)CH-TOG PROTEIN
KIAA0463Plexin 2 precursorKIAA0144(1)
KIAA1014(1)Formin-binding protein 30
KIAA1199(1)
KIAA1374(1)
KIAA0543KIAA1043(1)
KIAA1218(1)
KIAA0578Neurexin I-αKIAA0300(1)PDZ domain-containing protein AIPC
KIAA0440(1)High-risk human papilloma viruses E6 oncoproteins targeted protein E6TP1 α
KIAA0865(1)
KIAA1251(2)Trabeculin-α
KIAA0603[iii] KIAA0332(2)
KIAA0765(2)RNA binding motif protein 12
KIAA1498(2)p400 SWI2/SNF2-related protein
KIAA1546(2)
KIAA0620KIAA1251(1)Trabeculin-α
KIAA0690KIAA0109(1)Clathrin coat assembly protein AP50
KIAA0812[iii] MEGF2/FlamingoKIAA0640(9)SWAP-70 homolog
KIAA0728(3)Bullous pemphigoid antigen 1-a (Bpag1)
KIAA0816MEGF7KIAA1526(2)
KIAA0868Contactin associated protein-like 2 (Caspr2)KIAA0155(10)TPR-containing/SH2-binding phosphoprotein
KIAA1224(1)
KIAA1251(2)Trabeculin-α
KIAA0911Calsyntenin-1KIAA0045(2)Thyroid hormone receptor interactor 12
KIAA0067(1)ERG-associated protein ESET
KIAA0204(3)CTCL tumor antigen se20-9
KIAA0572(2)80-kDa MCM3-associated protein
KIAA1447(3)
KIAA0921Neurexin 2-αKIAA1251(1)Trabeculin-α
KIAA0960KIAA0400(3)
KIAA0987Band 4.1-like protein 3KIAA0912(1)
KIAA1032(2)Munc13–1
KIAA1062ATP-binding cassette, sub-family AKIAA1633(5)
KIAA1132KIAA0705(8)Synaptic scaffolding protein S-SCAM
KIAA1092(2)PLC-L2 mRNA for phospholipase C-L2
KIAA1634(14)Membrane-associated guanylate kinase-related MAGI-3
KIAA1206Plexin-B3 (PLXNB3)KIAA0076(3)
KIAA0275(1)Testican-2
KIAA0380(5)RhoGEF glutamate transport modulator GTRAP48
KIAA0705(1)Synaptic scaffolding protein S-SCAM
KIAA0708(1)KIAA0076 homolog (62%)
KIAA0952(1)
KIAA1634(3)Membrane-associated guanylate kinase-related MAGI-3
KIAA1216Vitamin D3 receptor interacting proteinKIAA0235(1)Pumilio 2
KIAA0593(1)Thyroid hormone receptor-associated protein complex component TRAP240
KIAA1037(1)
KIAA1041(1)
KIAA1278FUSED serine/threonine kinaseKIAA0316(2)
KIAA0807(3)Microtubule-associated serine/threonine protein kinase
KIAA1633(1)
KIAA1368Semaphorin 6AKIAA0777(1)SH3-containing protein p4015
KIAA1256(1)Intersectin 2 (SH3D1B)
KIAA1296(6)R85FL
KIAA1494(6)SH3 domains-containing protein POSH
KIAA1394KIAA0045(4)Thyroid hormone receptor interactor 12
KIAA1549KIAA0728(1)Bullous pemphigoid antigen 1-a
KIAA1119(1)MYOSIN VB
KIAA1121(1)Calcium-dependent actin-binding protein
KIAA1256(1)Intersectin 2 (SH3D1B)
KIAA1461(1)
KIAA1573KIAA0240(1)
KIAA1177(2)HCNP protein; XPA-binding protein 2
KIAA1224(2)
KIAA1464(1)RanBPM homolog (66%)
KIAA1679KIAA1464(5)RanBPM homolog (66%)
KIAA1746KIAA0465(1)Actin binding protein ABP620
KIAA1763CASPR4KIAA0561(1)Microtubule- and syntrophin-associated serine–threonine protein kinase homolog (63%)
KIAA0875(1)F-box only protein 21
KIAA1251(1)Trabeculin-α
KIAA1464(8)RanBPM homolog (66%)
KIAA1780[iii] MEGF10KIAA0109(5)Clathrin coat assembly protein AP50
KIAA0207(2)Growth factor receptor-bound protein 10
KIAA0577(2)Putative pre-mRNA splicing factor RNA helicase
KIAA0788(2)U5 small nuclear ribonucleoprotein 200 kDa helicase
KIAA1464(2)RanBPM homolog (66%)

[i] The number in parentheses represents the number of independent, isolated, positive clones.

[ii] Homologous genes whose sequences are more than 80% identified are detailed in the description column. Concerning annotation worth being described but lower than 80% identity, the percent identity is given in parentheses.

[iii] When 10 or more preys were identified, only preys prepared from two or more independent clones were listed because the bait may contain a sticky region.

[iv] All interaction data in this report are available in the public database BIND (BIND ID 12487–12570; http://www.bind.ca).