Table 2.

Breakpoints in the pUR288 Transgene and the Mouse Genome of the Two Integration Sites and a Representative Selection of Genome Rearrangements

53865-4t2_L1TT_rev1

[i] The capitalized nucleotides represent the recovered mutant sequence. Bold letters indicate direct homology between the breakpoint in the transgene and the mouse genome.

[ii] Mouse sequence directly 5′ of the integration site. The hyphen represents the transition to the integrated pUR288 sequence 3′ of the PstI site (in italics).