Classification of 714 Clear-Hit Drosophila Genes According to Human Disease Phenotypes
| Disorder | No. of genes |
| Neurological | 74 |
| Neuromuscular | 20 |
| Neuropsychiatric | 9 |
| CNS/Developmental | 8 |
| CNS/Ataxia | 9 |
| Mental retardation | 6 |
| Other | 22 |
| Endocrine | 50 |
| Diabetes | 10 |
| Other | 40 |
| Deafness | 13 |
| Syndromic | 7 |
| Nonsyndromic | 6 |
| Cardiovascular | 26 |
| Cardiomyopathy | 10 |
| Conduction defects | 4 |
| Hypertension | 7 |
| Atherosclerosis | 3 |
| Vascular malformations | 2 |
| Ophthalmologic | 43 |
| Anterior segment | (13) |
| Aniridia | 1 |
| Rieger syndrome | 1 |
| Mesenchymal dysgenisis | 2 |
| Iridogoniodysgenisis | 2 |
| Corneal dystrophy | 2 |
| Cataract | 3 |
| Glaucoma | 2 |
| Retina | (30) |
| Retinal dystrophy | 1 |
| Choroiderimea | 1 |
| Color vision defects | 4 |
| Cone dystrophy | 2 |
| Cone rod dystrophy | 1 |
| Night blindness | 8 |
| Leber congenital amaurosis | 2 |
| Macular dystrophy | 4 |
| Retinitis pigmentosa | 7 |
| Pulmonary | 4 |
| Gastrointestinal | 13 |
| Renal | 13 |
| Immunological | 33 |
| Complement mediated | 11 |
| Other | 22 |
| Hematologic | 42 |
| Erythrocyte, general | 29 |
| Porphyrias | 7 |
| Platelets | 6 |
| Coagulation abnormalities | 28 |
| Malignancies | 79 |
| Brain | 3 |
| Breast | 4 |
| Colon | 11 |
| Other gastrointestinal | 3 |
| Genitourinary | 5 |
| Gynocologic | 3 |
| Endocrine | 3 |
| Dermatologic | 3 |
| Xeroderma pigmentosa | 6 |
| Other/sarcomas | 9 |
| Hematologic malignancies | 29 |
| Skeletal development | 26 |
| Craniosynostosis | 5 |
| Skeletal dysplasia | 13 |
| Other | 8 |
| Soft tissue | 2 |
| Connective tissue | 18 |
| Dermatologic | 25 |
| Metabolic/mitochondrial | 123 |
| Pharmacologic | 12 |
| Peroxisomal | 9 |
| Storage | 37 |
| Glycogen storage | 11 |
| Lipid storage | 13 |
| Mucopolysaccaridosis | 10 |
| Other | 3 |
| Pleitropic developmental | 35 |
| Growth, immune, cancer | 7 |
| Apoptosis | 1 |
| Other | 27 |
| Complex other | 9 |
| Total | 714 |
[i] Totals for categories of disease are in bold, subcategory totals are in parenthesis, and individual categories are in plain text.