Table 2.

Linear Correlation Coefficients between Amino Acid Properties and Amino Acid Frequencies Observed in Hydrophilic I-c Regions

Amino acid property P. falciparum
Hydrophobicity
Kyte & Doolittle (1982) −0.23 (−0.70 ÷ 0.37)
Karplus (1997) −0.15 (−0.65 ÷ 0.44)
Volume (NIST Chemistry WebBook)−0.02 (−0.57 ÷ 0.54)
Flexibility (Vihinen et al. 1994)0.44 (−0.15 ÷ 0.80)
A content in codons0.73 (0.29 ÷ 0.91)
T content in codons−0.08 (−0.61 ÷ 0.50)
Amino acid property S. cerevisiae D. discoideum
Hydrophobicity
Kyte & Doolittle (1982) −0.23 (−0.70 ÷ 0.37)−0.26 (−0.71 ÷ 0.34)
Karplus (1997) −0.31 (−0.74 ÷ 0.30)−0.37 (−0.77 ÷ 0.23)
Volume (NIST Chemistry WebBook)−0.43 (−0.79 ÷ 0.16)−0.40 (−0.78 ÷ 0.20)
Flexibility (Vihinen et al. 1994)0.67 (0.18 ÷ 0.89)0.63 (0.11 ÷ 0.88)
A content in codons0.40 (−0.20 ÷ 0.78)0.53 (−0.03 ÷ 0.84)
T content in codons−0.33 (−0.75 ÷ 0.27)−0.30 (−0.73 ÷ 0.31)