Table 1.

Comparative Analysis of Hydrophilic Low-Complexity Segments in Different Lower Eukaryotes

P. falciparum chr. 2 P. falciparum chr. 3 P. berghei S. cerevisiae chr. II D. discoideum
Total proteins20521534428491
Proteins containing I-c segments88.2%94.0%n.d.52.8%n.d.
Complex segments598 (47109 aa)690 (55558 aa)59 (10843 aa)685 (137082 aa)1056 (180577 aa)
I-c segments identified by SEG415 (98662 aa)491 (121017 aa)35 (6404 aa)379 (43454 aa)624 (89259 aa)
Hydrophilic I-c segments357 (92371 aa)449 (116367 aa)32 (6150 aa)300 (36128 aa)541 (80519 aa)
A+T content in coding regions75.7%76.8%68.9%60.4%67.6%
h I-c compl h I-c compl h I-c compl h I-c compl h I-c compl
Percentual amino acidA1.452.901.223.393.795.055.705.533.285.21
Composition in hydrophilicC1.352.601.532.550.702.800.401.540.961.85
Low complexity (h I-c) and inD6.775.747.355.576.285.766.375.744.815.66
Complex (compl) segmentsE8.076.567.146.26 9.80 6.90 7.536.076.746.07
F3.705.143.845.732.624.372.514.832.374.84
G2.614.282.214.173.385.733.895.404.605.90
H2.402.612.522.741.231.862.002.301.712.22
K 13.29 9.70 12.90 9.70 12.49 8.55 7.867.287.307.37
I9.078.409.329.619.908.254.966.896.497.55
L6.908.416.889.307.338.837.999.517.038.68
M2.062.672.112.701.192.091.502.200.912.22
N 16.38 8.53 18.13 8.59 11.66 6.94 8.19 5.69 12.97 5.79
P1.572.961.563.003.063.645.084.305.184.18
Q2.653.122.543.143.402.74 5.57 3.71 7.98 4.09
R2.253.312.363.471.983.544.194.602.624.03
S6.276.676.186.578.039.79 12.96 8.00 12.04 7.48
T4.024.963.654.805.195.196.915.626.975.71
Y5.445.616.276.214.284.412.063.742.223.76
V3.535.043.285.123.455.854.105.863.546.21
W0.190.950.220.960.260.930.280.280.271.12