Table 2.

Topologies of Four-Member Families and Clusters of Four Genes in 5–8-Member Families of Human and Drosophila

Human Drosophila
Four-member families
 At least one duplication before deuterostome-protostome divergence32 (25)[ii] 16 (11)[ii]
 All duplications after deuterostome-protostome divergence
  topology (AB)(CD)[iii] 22 (11)[v] 4 (2)[v]
  topology (A) (BCD)[iv] 38 (17)[v] 2 (1)[v]
 Unresolved14 2 
 Total106 24 
Four-member clusters in 5–8-member families
 topology (AB) (CD)[iii] 17 (5)[v] 5 (3)[v]
 topology (A) (BCD)[iii] 25 (10)[v] 6 (2)[v]
 unresolved8 0 
 total50 11 

[i] Numbers are numbers of families showing a given topology.

[ii] Numbers in parentheses are numbers of families in which the branch establishing duplication prior to the deuterostome-protostome divergence received significant support.

[iii] As in Figure 1c.

[iv] As in Figure 1d.

[v] Numbers in parentheses are cases where the branches establishing the topology (marked with arrows in Figs. 1c and 1d) received significant support.