Table 3.

Divergence in the 42.6 kb NCTC 11168 Capsule Biosynthetic Locus in theCampylobacter jejuni Strains Studied

Gene name Function[iii] Clone content (%) Phase variable[iv] 81116 81-176 X G1 P1 P2 P3 P4 PHLS 01 PHLS 02 PHLS 03
Cj1413 kpsS Cj1413 (67)+++++++++++
Cj1414 kpsC Cj1413(16)+++++++++++
Cj1414 (50)
Cj1415 cysC Cj1414(20)(+)++++++++++
Cj1415 (100)
Cj1416 (17)
Cj1416 sugar Cj1416(82)+++++++++++
nucleotidyltransferase
Cj1417 GMP synthetase Cj1416(22)+++++++++++
Cj1417 (98)
Cj1418 phosphoenolpyruvate Cj1418(39)+++++++++++
synthase
Cj1419 methyltransferase Cj1418(9)+++++++++++
Cj1419 (77)
Cj1420 unknown Cj1420(73)√+++++++(+)+++
Cj1421 sugar transferase Cj1421(33)√(+)++++++(+)+++
Cj1422 sugar transferase Cj1422(89)√−+−+++(+)−+++
Cj1423 sugar-phosphate Cj1423 (100)−(+)(+)+++(+)(+)+(+)+
nucleotidyltransferase Cj1424 (100) 
Cj1425(3) 
Cj1424 gmhA2 Cj1423(22)+++++++++++
Cj1424 (100)
Cj1425 (4)
Cj1425 galactose kinase Cj1424(22)−+(+)−−++++++
Cj1425(100)   
Cj1426(20)   
Cj1426 unknown Cj1425(2)√−+−−−+−(+)+++
Cj1426(100)     
Cj1427(46)     
Cj1427 sugar-nucleotide Cj1427(75)−+−+++(+)++++
epimerase/dehydratase  
Cj1428 fucose synthetase Cj1427(28)−(+)−+−+−−+++
Cj1428(100)     
Cj1429(6)     
Cj1429 unknown Cj1428(14)√−+−+−+−−+++
Cj1429(100)     
Cj1430(42)     
Cj1430 nucleotide-sugar Cj1429(29)+++++++++++
epimerase/dehydratase Cj1430(100)
Cj1431(7)
Cj1431 glycosyltransferase Cj1431(43)−−−−++−−+++
Cj1432 glycosyltransferase Cj1432(45)−−−−−+−−+++
Cj1433 unknown Cj1432(2)√−−−+++−−+++
Cj1433(71)     
Cj1434 galactosyltransferase Cj1434(55)−+−+++(+)−+++
Cj1435 phosphoserine Cj1435(100)(+)+++++(+)++++
phosphatase Cj1436(4)
Cj1436 aminotransferase Cj1436(89)−+−+++(+)(+)+++
Cj1437 aminotransferase Cj1437(84)−(+)−+−+−−+++
Cj1438(2)     
Cj1438 galactosyltransferase Cj1438(42)−(+)−++++−+++
Cj1439 UDP-galactopyranose Cj1439(75)−−−+−+−−+++
mutase      
Cj1440 galactosyltransferase Cj1440(52)−(+)−+(+)+−−+++
Cj1441(11)    
Cj1441 kfiD Cj1440(3)−−−−++−−+++
Cj1441(73)      
Cj1442 glycosyltransferase Cj1442(47)+++−+(+)++(+)++
Cj1443 kpsF Cj1443(63)+++++++++++
Cj1444 kpsD Cj1444(74)+++++++++++
Cj1445 kpsE Cj1445(65)+++++++++++
Cj1447 (38)
Cj1447 kpsT Cj1445(25)+++++(+)++(+)++
Cj1447 (100)
Cj1448(13)
Cj1448 kpsM Cj1447(44)++(+)(+)+++++++
Cj1448 (100)

[i] A + or − indicates that the red/green hypridization signal intensity ratio is >0.5 or <0.5, respectively.

[ii] (+) indicates the possibility that the gene may be absent or highly divergent even though the red/green hybridization signal intensity ratio is >0.5 (see Methods).

[iii] Putative gene function based on annotation (Parkhill et al. 2000).

[iv] Genes contain intragenci homopolymeric tracts indicating potential phase variable expression (Parkhill et al. 2000).

[v] NB: Cj1446 was originally designated a CDS, but was unannotated in the final genome annotation (Parkhill et al. 2000).