Table 2.

Germline Transmission of the HCV by the Two Male Chimeras

Parent Produced litters HCV+ agouti pups/total number ofagouti pups Percent germline transmission
Chimera 10/10/71/73/113/81/63/1122%
Chimera 20/20/55/74/76/133/52/85/103/93/544%

[i] Two male transchromosomal chimeras were mated with C57BL/6 mice. The produced litters are shown.