Strain-Specific Mutation Profile
| Common site | Gene | Map location[i] | Insertion frequency (%)[ii] | ||||
| AKXD-10 | AKXD13 | AKXD-18 | AKXD-27 | ||||
| Lvis1 | Hex, Eg5 | 19 (26)[iii] | 0 | 11 | 14 | 5 | |
| Lvis2 | unknown | 7[iii] | 0 | 0 | 5 | 2 | |
| Lvis3 | unknown | 13[iii] | 0 | 0 | 5 | 0 | |
| Lvis4 | unknown | 12[iii] | 1/4 | 0 | 0 | 2 | |
| Lvis5 | Alx4 | 2 (65) | 0 | 0 | 2 | 2 | |
| Lvis6 | Hex | 19 (26)[iii] | 0 | 0 | 0 | 5 | |
| Lvis7 | Rel | 11 (13) | 0 | 0 | 0 | 5 | |
| Lvis8 | CcnD3 | 17 | 0 | 0 | 0 | 2 | |
| Lvis9 | Sox4 | 13 | 0 | 0 | 0 | 2 | |
| Evi3 | Evi3 | 18 (5)[iii] | 0 | 0 | 0 | 20 | |
| N-myc | N-myc | 12 (4) | 0 | 0 | 5 | 2 | |
| Gfi1 | Gfi1 | 5 (56) | 0 | 0 | 0 | 2 | |
| Myc | Myc | 15 (32) | 0 | 0 | 2 | 0 | |
| Notch1 | Notch1 | 2 (15) | 0 | 6 | 0 | 0 | |
[i] Mouse chromosomal map locations either were determined in our laboratory or are based on published data. Primary mapping data are available from the Mouse Genome Informatics database (http://informatics.jax.org). Numbers in parentheses represent estimated distance from the centromere in centimorgans as assigned by MGD.
[ii] Insertion frequency is calculated from a total of 18 AKXD-13 tumors, 42 AKXD-18 tumors and 41 AKXD-27 tumors, where the AKXD-10 frequency is shown as a fraction due to the number of tumors analyzed (4).
[iii] Map locations determined using an (SB/Le × M. spretus)F1 × SB/Le interspecific backcross (Justice et al. 1990).