Table 2.

Comparison of the 15 Most Expressed Tags in the Mouse Brain Transcriptome

TAG sequence Mouse UniGene no. pA signal Human UniGene no. Mouse gene description No. of mice TAGs No. of human TAGs
GTGGCTCACA4184YesMultiple matches2626
GCTTCGTCCA2992Yes69547Myelin basic protein1013261
AGCAGTCCCC3776NoTAG matches mitochondrial sequence870
TCAGGCTGCC1776Yes62954Ferritin heavy chain573440
GCACAACTTG18041NoMultiple matches554
GTGACCTGGC1008Yes8272Prostaglandin D2 synthase (21 kD, brain)496282
GCCTCCAAGG5289Yes195188Glyceraldehyde-3-phosphate dehydrogenase490302
AAAAAAAAAA15295YesMultiple matches481
GAGCGTTTTG5246Yes182937Peptidyl-prolycis-trans isomerase A475142
CAAACCTCCA28177NoTAG matches mitochondrial sequence400
CATCGCCAGT21417Yes169401Apolipoprotein E397191
AGCAATTCAA30071NoTAG matches mitochondrial sequence390
AATTCGCGGANo match375
CCTTGCTCAA43036Yes135084Cystatin C347274
TGACCCCGGG43766YesUbiquitin/60s ribosomal fusion protein333

[i] The corresponding mRNA to each tag has been determined when possible. The human homolog for most of these was determined using UniGene searches. For each mouse tag sequence the numbers of detected copies in ∼150,000 tags from mouse brain SAGE libraries (No. of mice tags) are shown. The presence of polyadenylation signal in the corresponding mouse UniGene entry (Mouse UniGene no.) was noted (pA signal). The corresponding human transcript was obtained from the human UniGene library (Human UniGene no.) and the number of tags representing this transcript in 150,000 tags from human brain SAGE library was determined (No. of human tags). Mouse transcripts with known poly(A) signal for which the homolog was detected in the human brain transcriptome are shaded in gray.