Table 1.

The Most Abundant Transcripts in Human Tissues

B01.hl60 857 C08.Aortic media 1002 N01. Retina 877 X01.hepG2 740
Ribosomal protein S8 X67247 24Elastin M17282 155Opsin K02281 14EF-1α X16869 17
Ribosomal protein L9 U09953 22Osteonectin J03040 27Na/K ATPase β2 D87330 13Albumin L00133 17
Ribosomal protein L23 X53777 17Ribosomal protein L21 X89401 16Aldolase C X07292 10TPT-1 X16064 9
Ribosomal protein L7a X52138 16GS13325None16Ribosomal protein L9 U09953 9Ribosomal protein L31 X69181 9
B02. hl60/DMSO 1081 C09. Ventricle muscle 3785 N02. Cortex 2242 X02. Neonate liver 739
β-actin X00351 14Myosin heavy chain M25139 101Myelin basic protein M13577 49Albumin L00133 227
HHCPA78 homolog S73591 6Ig-λ light chain D01059 75hng/RC3 Y15059 14Apolipoprotein B J02775 38
Ribosomal protein L3 M90054 5Myoglobin X00373 60Apolipoprotein J M74816 13α2-HS-glycoprotein M16961 21
L-plastin L05492 5Troponin C, skel/card M37984 53Aldolase C X07292 9Haptoglobin α 1S X00637 16
B03. hl60/TPA 889 C10. atrial muscle 2823 N03. cerebellum 1107 X03. fetal liver 641
EF-1α X16869 26ANF M54951 203GFAP S40719 22Albumin L00133 109
Methionine AT-a L43509 14Actin, a-cardiac J00073 88Aldolase C X07292 7Haptoglobin α 1S X00637 27
Ferritin L M11147 14α B-crystallin S45630 27Myelin basic protein M13577 5γ-G globin X55656 17
TPT-1 X16064 13Troponin T, cardiac X74819 25Apolipoprotein J M74816 5Apolipoprotein All X04898 14
B04. granulocyte 1164 C11. Skeletal muscle 4527 N04. Neuroblast 1235 X04. Adult liver 956
β-2-microglobulin M17987 25α-actin, skeletal M20543 301EF-1α X16869 19Albumin L00133 279
Spermidine/spermineAT M77693 22Myosin heavy chain X03741 173H3.3 histone M11354 17Haptoglobin α 1S X00637 41
HLA-Cw1 M26429 21Myosin heavy chain X03740 137ribosomal protein L9 U09953 16α-1 acid gp M13692 20
Pre-B enhancing factor U02020 20Troponin C, skeletal X07898 121TPT-1 X16064 15Apolipoprotein B J02775 19
B05. CD8 T cell 1104 C12. Hair follicle 2164 N05. Caudate nucl. 1077 X05. Lung 874
β-2-microglobulin M17987 16Fibronectin K00799 84hng/RC3 Y15059 12Pulmonary SAP M30838 87
TPT-1 X16064 12COL1A1 M32798 57TALLA-1 D29808 11Clara cells 10 kd prot. U01101 31
EF-1a X16869 10EF-1α X16869 43Myelin basic protein M13577 8HLA-E heavy chain X64881 12
Yeast rp L4 homolog Z12962 10Osteonectin J03040 30KIAA0607 AB011179 7Fibronectin K00799 10
B06. CD4 T cell 1028 E1. Keratinocyte 820 N06. Thalamus 912 X06. Colon mucosa 921
β-2-microglobulin M17987 19Cytokeratin 14 J00124 15Myelin basic protein M13577 36L-FABP M10617 40
Ribosomal protein L11 X79234 14Metallothionein V00594 10GFAP S40719 8Galectin-4AF0148318
TPT-1 X16064 13Lipocortin II D00017 9apo J M74816 7CLCA1AF0394013
23 kD highly basic protein X56932 12Ribosomal protein S19 M81757 8Sox 8 AF164104 6Ig-λ-light chain D01059 12
C01. Adipose tissue 1488 E02. Cornea 2793 N07. Putamen 871 X07. Small cell ca. lung 843
Gelatin BP AB012165 19Apolipoprotein J M74816 73Myelin basic protein M13577 8BBC1 X64707 8
Ribosomal protein S8 X67247 16Cytokeratin 12 D78367 55GS04506None823 kD highly basic prot. X56932 7
apM2 D45370 15apM2NM00682940TPT-1 X16064 7Ribosomal protein S11 X06617 7
TPT-1 X16064 14Ferritin H M11146 31Na/K ATPase β2 D87330 7Ribosomal protein L7a X52138 6
C02. Aortic endothel* 967 E03. Conjunctiva 937 N08. Astrocyte* 1103 X08. Adeno ca. of lung 1183
Fibronectin K00799 36β-2-microglobulin M17987 23EF-1α X16869 26COL3A1 X14420 20
TPT-1 X16064 14Cytokeratin 13 X52426 23Ribosomal protein S17 M13932 14Thymosin β4 M17733 15
PAI-1 X13345 12Lipocortin X05908 8GFAP S40719 12Ig-λ light chain D01059 14
CTGF X78947 12EF-4All D30655 8Thymosin β4 M17733 10Ig-κ light chain M11937 13
C03. Osteoblast* 928 E04. Intest. Metaplasia 2192 N09. Schwann cell* 975 X09. Squamous cell ca. lung 1190
COL1A2 J03464 25Calcyclin J02763 25Ribosomal protein L10 AB007170 18Calcyclin J02763 23
Fibronectin K00799 22EF-1α X16869 20Ribosomal protein L9 U09953 17Ferritin L chain M11147 14
Osteonectin J03040 20Aminopeptidase N M22324 17Ribosomal protein S19 M81757 17Cystatin B L03558 11
COL3A1 X14420 18PSCA AF043489 17Ribosomal protein S29 U14973 15Cathepsin B L16510 9
C04. Fibroblast* 1097 E05. Fundic gland 3304 N10. Fetal neuron* 1108 X10. Iris 3314
Stromelysin X05232 26Pepsinogen J00287 572Ribosomal protein L37a X66699 9Apolipoprotein D M16696 45
Fibronectin K00799 22Lysozyme X14008 33TPT-1 X16064 91-8D X57351 43
Collagenase X05231 15Gastric lipase X05997 32Ribosomal protein L5 U14966 8Yeast rp L41 homolog Z12962 42
PAI-1 X13345 14TPT-1 X16064 29Thymosin β4 M17733 8TPT-1 X16064 40
C05. Mesangium 1101 E06. Ileum epithel 3675 N11. Corpus callosum 949 X11. Skin full thickness 4604
Fibronectin K00799 48β-2-microglobulin M17987 59GFAP S40719 12Yeast rp L41 homolog Z12962 59
Calcyclin J02763 30CLCA1 AF039400 51Ribosomal protein L37a X66699 7GS20959None58
ribosomal protein S19 M81757 13defensin 6 M98331 46ribosomal protein S8 X67247 7ribosomal protein S18 X69150 57
Yeast rp S28 homolog D14530 10GS2706None34Myelin basic protein M13577 7Delta-6 desaturaseAF0367957
C06. Itoh cell 1283 E07. Colon epithel 6451 N12. Substantia nigra 3477 X12. Tumor infiltrates 1585
Osteonectin J03040 23Galectin-4 AF014838 106Myelin basic protein M13577 129β-2-microglobulin M17987 49
Fibronectin K00799 18cytokeratin 8 X12882 86Ribosomal protein L7a X52138 51LD78α D90144 31
PAI-1 X13345 16L-FABP M10617 78EF-1α X16869 48RF-1α X16869 25
EF-1α X16869 16Calcyclin J02763 75αB-crystallin S45630 46Yeast rp S28 homolog D14530 24
C07. Bone flakes 1042 E08. Pituitary 1015 N13. Fetal brain 3797
Osteonectin J03040 25Prolactin M29386 181α-Tubulin X01703 35
COL1A2 J03464 24Growth hormone M13438 20Ribosomal protein L37a X66699 21
β-Globin V00497 13Secretogranin I Y00064 12EF-1α X16869 20
COL3A1 X14420 12sGTP-bp X07036 9Stathmin J04991 16

[i] The source tissue or cells and the number of total ESTs representing chromosomally encoded genes are given (shaded cells). The source groups were blood cells (B01–B06), connective and muscular tissues (C01–C12), epithelial tissues (E01–E08) and nervous tissues (N01–N13). When the source tissue was composed of multiple cell types or an uncategorizable cell type, it was categorized as complex (X01–X12). Asterisks denote primary cultured cells. The identities of the most frequently isolated tags are given along with their frequencies. (TPT-1) Translationally controlled tumor protein; (methionine AT-a) methionine adenosyltransferase-α; (spermine AT) spermine acetyltransferase; (EF-1a) elongation factor 1-α; (apM2) adipose most abundant protein-2; (PAI-1) plasminogen activator inhibitor-1; (ANF) atrial atriuretic factor; (EF-4AII) elongation factor 4AII; (CLCA1) calcium activated chloride channel 1; (L-FABP) liver fatty acid binding protein; (sGTP-BP) stimulatory GTP bonding protein; (hng/RC3) human neurogranin; (GFAP) glial fibrillary acidic protein; (TALLA-1) T-cell acute lymphoblastic leukemia associated antigen 1; (pulmonary SAP) pulmonary surfactant apoprotein.