Table 3.

Global Sequence Comparison of Human 11p15 and the Orthologous Mouse Domain

FeatureMouseHuman
Total sequence915699 bp900050 bp
Known genes1616
 Exons112119
 Content28710 bp27890 bp
Novel transcripts67
GC content47.76%54.70%
CpG islands65119
Conserved CpG islands3333
 Conserved content17600 bp17600 bp
Conserved nonexonic, nonisland sequences4949
 Conserved content10007 bp10007 bp
Total interspersed repeats219 kb (23.96%)264 kb (29.38%)
 SINEs367 (5.24%)215 (5.25%)
 LINEs114 (8.08%)192 (16.37%)
 LTR elements170 (7.68%)104 (6.37%)
 MERs, Mariners20 (0.41%)53 (1.4%)
Total simple repeats294 (2.07%)153 (1.92%)
 Small RNA repeats3 (0.02%)2 (0.02%)
 Low complexity repeats69 (0.48%)63 (0.54%)

[i] The percent of conserved sequence (4.2%) is calculated by dividing the sum of the conserved CpG island content and non-exonic non-island content, by the aligned mouse sequence excluding the human sequence not yet completed.