Markup | Genome Research

Table 1.

Significant and Suggestive QTL Associations Detected by the Genome Scans for Main Effects

Chr.	cM	Marker	BW8	BW16	BW24	PI16	LOG PG24	BMI	AI	Leptin
1	8.3	D1Mit296	4.12[iii]	2.69	2.89		2.18	1.98
1	15.0	D1Mit211	7.03[iii]	5.36[iii]	6.13[iii]	3.01	3.48[iii]	3.42[iii]
1	18.5	D1Mit411	9.28[iii]	7.23[iii]	7.54[iii]	4.57[iii]	4.85[iii]	4.25[iii]
1	21.0	D1Mit123	9.36[iii]	6.69[iii]	7.00[iii]	4.37[iii]	4.92[iii]	4.07[iii]
1	25.7	D1Mit213	8.32[iii]	5.66[iii]	5.75[iii]	4.10[iii]	4.63[iii]	3.18
1	32.8	D1Mit76	8.49[iii]	4.91[iii]	4.99[iii]	3.82[iii]	4.00[iii]	2.00
1	43.1	D1Mit46	4.61[iii]	2.93	2.77	2.55	2.09
3	33.7	D3Mit22				2.53
5	28.0	D5Mit81							2.81
5	45.0	D5Mit7							3.86[iii]	3.18
6	25.5	D6Mit275	2.16	2.48		1.92
6	29.0	D6Mit123
12	45.0	D12Mit259	2.14		2.04			2.45	3.42[iii]	2.34
12	48.0	D12Mit231	2.00	2.45	3.07			3.96[iii]	4.88[iii]	3.34[iii]
12	52.0	D12Mit132			2.50			3.29[iii]	4.47[iii]	3.22[iii]
12	53.0	D12Mit262						2.85	4.28[iii]	3.5[iii]
12	59.0	D12Mit150						2.21	2.85	2.46
13	62.0	D13Mit53						2.03
15	6.7	D15Mit13	2.89	2.39
15	15.4	D15Mit22		2.20				2.21		2.06
15	29.0	D15Mit26		2.67	2.48			2.61	2.30	3.02
15	49.0	D15Mit72			2.34		2.88	2.20	2.58
15	49.6	D15Mit159		2.01	2.29		3.55[iii]		2.30
15	57.8	D15Mit217			2.17		2.99		2.15
15	59.2	D15Mit42					2.11
18	16.0	D18Mit60						1.90	2.47

[i] (Chr) chromosome; (BW) body weight; (PG) plasma glucose; (BMI) body mass index; (QTL) quantitative trait loci; (AI) adiposity index.

[ii] BW is shown at three different time points, 8, 16, and 24 weeks of age. Plasma Insulin (PI) is shown at the 16 wk time point. LOG PG, BMI, AI, and serum leptin are shown at the 24-week time point.

[iii] Exceeds the LOD 3.3 criterion for significance proposed byLander and Kruglyak (1995). Centimorgan position from the Mouse Genome Database maintained by The Jackson Laboratory (www.informatics.jax.org).