Test Crosses of C3H and C57BL/6J Alleles of k10 Using theMgfSl Mutation
| Hypopigmentation | Mgf Sl /Mgf C3H | Mgf C3H /Mgf C3H | Mgf Sl /Mgf C57BL/6J | Mgf C3H /Mgf C57BL/6J | |
| Head spot | F1 [ii] | 100% (4/4) | 0% (0/4) | 0% (0/14) | 0% (0/14) |
| BC1 [iii] | 94% (16/17)[iv] | 0% (0/13) | 0% (0/13) | 0% (0/11) | |
| Dorsal spot | F1 [ii] | 0% (0/4) | 0% (0/4) | 0% (0/14) | 0% (0/14) |
| BC1 [iii] | 0% (0/17) | 0% (0/13) | 0% (0/13) | 0% (0/11) | |
[i] Ranged from several white hairs to large spot.
[ii] From matings of C3HeBFeJ/LeMgfSl/MgfC3H; × C3HeBFeJ/Le MgfC3H (forMgfSl/MgfC3H andMgfC3H/MgfC3H mice) and C3HeBFJ/Le MgfSl/MgfC3H;× C57BL/6J MgfC57BL/6J (forMgfSl/MgfC57BL/6J andMgfC3H/MgfC57BL/6J mice). All mice are wild type at Ednrb.
[iii] From matings of C3HeBFej/LeMgfSl/MgfC3H; × (C3HeBFeJ/Le MgfC3H × C57BL/6J MgfC57BL/6J ) F1. All mice are wild type at Ednrb.
[iv] Fisher's exact test p < 0.001.