Supplemental Table S7: Functional classifications for GWAS associations at sex-spefific eQTLs.
Trait: GWAS trait
Class: Functional classification

Trait	Class
Metabolic traits	Metabolic
Breast milk fatty acid composition (maternal genotype effect)	Metabolic
BMI (smoking interaction)	Obesity
BMI in smokers	Obesity
Body fat distribution (leg fat ratio)	Obesity
Body fat distribution (trunk fat ratio)	Obesity
Body mass index	Obesity
Body mass index (joint analysis main effects and smoking interaction)	Obesity
Fat-free mass	Obesity
Hip circumference	Obesity
Waist circumference adjusted for BMI (adjusted for smoking behaviour)	Obesity
Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction)	Obesity
Waist circumference adjusted for BMI in non-smokers	Obesity
Waist-hip ratio	Obesity
Weight	Obesity
Glycerophospholipid levels	Lipids
LDL cholesterol levels	Lipids
Phospholipid levels (plasma)	Lipids
Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid)	Lipids
Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)	Lipids
Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)	Lipids
Stearic acid (18:0) levels	Lipids
Total cholesterol levels	Lipids
Triglyceride levels	Lipids
Atrial fibrillation	Cardiovascular
Brugada syndrome	Cardiovascular
Cardiovascular disease	Cardiovascular
Coronary artery disease	Cardiovascular
Diastolic blood pressure	Cardiovascular
P wave duration	Cardiovascular
PR interval	Cardiovascular
Pulse pressure	Cardiovascular
QRS duration	Cardiovascular
QT interval	Cardiovascular
Resting heart rate	Cardiovascular
Systolic blood pressure	Cardiovascular
Blood pressure	Cardiovascular
Blood metabolite levels	Blood
Blood metabolite ratios	Blood
Blood protein levels	Blood
Mean corpuscular hemoglobin	Blood
Mean corpuscular volume	Blood
Mean platelet volume	Blood
Platelet count	Blood
Red blood cell count	Blood
Red cell distribution width	Blood
Urate levels	Blood
Venous thromboembolism	Blood
C-reactive protein levels	Immune
Eosinophil counts	Immune
Eosinophil percentage of granulocytes	Immune
Eosinophil percentage of white cells	Immune
High IL-1beta levels in gingival crevicular fluid	Immune
IgG glycosylation patterns	Immune
Monocyte count	Immune
Neutrophil percentage of granulocytes	Immune
Pediatric autoimmune diseases	Immune
Rheumatoid arthritis	Immune
Sum eosinophil basophil counts	Immune
TB-LM or TBLH-BMD (pleiotropy)	Immune
Crohn's disease	Immune
Inflammatory bowel disease	Immune
Ulcerative colitis	Immune
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)	Immune
Bone mineral density (paediatric, skull)	Osteo
Bone mineral density (paediatric, total body less head)	Osteo
Femoral neck bone mineral density	Osteo
Heel bone mineral density	Osteo
Total body bone mineral density	Osteo
Total body bone mineral density (age 0-15)	Osteo
Calcaneus stiffness index	Osteo
Asthma	Pulmonary
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy)	Pulmonary
Lung function (FEV1/FVC)	Pulmonary
Post bronchodilator FEV1	Pulmonary
Post bronchodilator FEV1/FVC ratio	Pulmonary
Pulmonary function	Pulmonary
Pulmonary function (smoking interaction)	Pulmonary
Estimated glomerular filtration rate	Renal
Serum metabolite ratios in chronic kidney disease	Renal
Basal cell carcinoma	Cancer
Breast cancer	Cancer
Core binding factor acute myeloid leukemia	Cancer
Keratinocyte cancer (MTAG)	Cancer
Lung adenocarcinoma	Cancer
Lung cancer	Cancer
Lung cancer in ever smokers	Cancer
Nasopharyngeal carcinoma (SNP x SNP interaction)	Cancer
Prostate cancer	Cancer
Hippocampal sclerosis of aging	Neurodegenerative
Age of smoking initiation (MTAG)	Cognitive/Behavioral/Psychiatric
Attention deficit hyperactivity disorder	Cognitive/Behavioral/Psychiatric
Bipolar disorder	Cognitive/Behavioral/Psychiatric
Chronotype	Cognitive/Behavioral/Psychiatric
Cognitive ability (MTAG)	Cognitive/Behavioral/Psychiatric
Cognitive performance (MTAG)	Cognitive/Behavioral/Psychiatric
Depressed affect	Cognitive/Behavioral/Psychiatric
Educational attainment	Cognitive/Behavioral/Psychiatric
Educational attainment (college completion)	Cognitive/Behavioral/Psychiatric
Educational attainment (MTAG)	Cognitive/Behavioral/Psychiatric
Educational attainment (years of education)	Cognitive/Behavioral/Psychiatric
Experiencing mood swings	Cognitive/Behavioral/Psychiatric
Extremely high intelligence	Cognitive/Behavioral/Psychiatric
Feeling fed-up	Cognitive/Behavioral/Psychiatric
General cognitive ability	Cognitive/Behavioral/Psychiatric
General factor of neuroticism	Cognitive/Behavioral/Psychiatric
Highest math class taken	Cognitive/Behavioral/Psychiatric
Highest math class taken (MTAG)	Cognitive/Behavioral/Psychiatric
Intelligence	Cognitive/Behavioral/Psychiatric
Intelligence (MTAG)	Cognitive/Behavioral/Psychiatric
Lifetime smoking index	Cognitive/Behavioral/Psychiatric
Morning person	Cognitive/Behavioral/Psychiatric
Morningness	Cognitive/Behavioral/Psychiatric
Reaction time	Cognitive/Behavioral/Psychiatric
Self-reported math ability	Cognitive/Behavioral/Psychiatric
Self-reported math ability (MTAG)	Cognitive/Behavioral/Psychiatric
Smoking behaviour (cigarettes smoked per day)	Cognitive/Behavioral/Psychiatric
Smoking initiation (ever regular vs never regular) (MTAG)	Cognitive/Behavioral/Psychiatric
Smoking status	Cognitive/Behavioral/Psychiatric
Worry	Cognitive/Behavioral/Psychiatric
Blood and toenail selenium levels	Other
Femoral neck section modulus	Other
Glycine levels	Other
Hair color	Other
Hand grip strength	Other
Height	Other
High altitude adaptation	Other
Intraocular pressure	Other
Medication use (calcium channel blockers)	Other
Recombination rate (females)	Other
Blond vs. brown/black hair color	Other
Primary sclerosing cholangitis	Other
Medication use (antithrombotic agents)	Other
Primary biliary cirrhosis	Other
Balding type 1	Sex-related
Male-pattern baldness	Sex-related
Menarche (age at onset)	Sex-related
Sex hormone-binding globulin levels	Sex-related
