There are three different subdirectories in the directory. dat contains files which are necessary to execute the scripts in the directory, and figures contains generated figures by the scripts. scripts-for-analysis contains snippets to parse and execute CB2.
*.R files are executable files and you can execute the scripts in Rstudio, or run Rscript <file-name-of-the-script.R. The following table describles the function of each script and what will be generated by the script.
| File name | Executable | Function |
|---|---|---|
| draw-fig-S12.R | Yes | The script to generate FPR plots of non-targeting sgRNA analysis using Sanson et al.’s data. |
| draw-fig-S13.R | Yes | The script to create Heatmaps and Venn diagrams to reveal discrepancy of sgRNA statistics between CB2 and MAGeCK |
| draw-fig-S15.R | Yes | The script to create mean-variance plots to claim CRISPR pooled data can be under/over-dispersed. |
| draw-fig3.R | Yes | The script to generate FPR plots of non-targeting sgRNA analysis using Parnas et al.’s data. |
| draw-fig4.R | Yes | The script to create Heatmaps and Venn diagrams to reveal discrepancy of sgRNA statistics between CB2 and MAGeCK. |