# CRE: Chromosomal position # TFID: JASPAR ID # TF_Name: Transcription Factor # Freq: Number of single base mutations that create or disrupt a particular TFBS # Type: Independent or Interacting for a particular substitution # Probability: Probability of Independent or Interacting assignment from 10000 shuffles of expression data # Position: Singe base mutation # start: Starting position of the motif match # stop: End position of the motif match # Parent Bin: Bin assignment of wild-type parent # broken: Motif created or mutated due to substitution # WT_exp: Effect of expression of a substitution in the wild-type parent # MUT_exp: Effect of expression of a substitution in the AP-1mut parent # SigWT: 1 = Significant different between single base mutation and wild-type parent, 0 = Difference is not significant # SigMUT: 1 = Significant different between single base mutation and AP-1mut parent, 0 = Difference is not significant # log_Mut_WT_ratio: Log of MUT_exp/WT_exp # Sig_ratio: 1 = Ratio higher than threshold, 0 = Ratio lower than threshold CRE TFID TF_Name Freq Type Probability Position start stop Parent_bin broken WT_exp MUT_exp SigWT SigMUT log_Mut_WT_ratio Sig_ratio chr1:16562648-16562697 MA0103.2 ZEB1 5 Interacting 0.0297 G_7 4 12 LOW created 0.493070641 0.734000414 1 1 -0.573986525 1 chr1:174784353-174784402 MA0103.2 ZEB1 5 Interacting 0.0297 G_6 4 12 LOW created 0.309347348 1.001422582 1 0 -1.694751321 1 chr14:36347890-36347939 MA0842.1 NRL 14 Interacting 0 T_20 16 26 MED created 1.399447876 0.869665659 1 0 0.686324982 1 chr16:12049767-12049816 MA0079.3 SP1 5 Interacting 0.0085 C_32 28 38 HIGH created 0.943531705 1.340348647 0 1 -0.506465417 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 A_33 32 46 HIGH mutated 0.315424654 0.499603023 1 1 -0.663486777 1 chr18:10530994-10531043 MA0156.1 FEV 4 Interacting 0.0254 C_32 31 38 HIGH created 0.917310968 1.90662766 0 1 -1.055540336 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 G_41 32 46 HIGH mutated 0.789334037 1.524995092 1 1 -0.950096733 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 C_39 32 46 HIGH mutated 0.615346746 1.21408695 1 1 -0.980400249 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 A_34 32 46 HIGH mutated 0.326093048 0.518162215 1 1 -0.668120132 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 T_35 32 46 HIGH mutated 0.412723919 0.649917276 1 1 -0.655079047 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 T_38 32 46 HIGH mutated 0.560023438 1.047494458 1 0 -0.903383498 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 G_37 32 46 HIGH mutated 1.103189842 2.42240178 0 1 -1.134757093 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 G_35 32 46 HIGH mutated 0.321558841 0.793114853 1 1 -1.302447047 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 C_41 32 46 HIGH mutated 0.672573005 1.386954997 1 1 -1.044158197 1 chr18:10530994-10531043 MA0103.2 ZEB1 5 Interacting 0.0297 G_10 7 15 HIGH created 0.180541543 0.489496023 1 1 -1.438966295 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 T_39 32 46 HIGH mutated 0.641963944 1.321608523 1 1 -1.041730721 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 A_36 32 46 HIGH mutated 0.433449924 0.690918661 1 1 -0.672650548 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 C_38 32 46 HIGH mutated 0.559750516 0.915428728 1 0 -0.709663614 1 chr18:10530994-10531043 MA0156.1 FEV 4 Interacting 0.0254 T_32 31 38 HIGH created 0.902355698 1.406022811 0 1 -0.639851857 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 A_39 32 46 HIGH mutated 0.520708244 1.262067026 1 1 -1.277241379 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 A_35 32 46 HIGH mutated 0.450029617 0.719081928 1 1 -0.676136203 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 G_36 32 46 HIGH mutated 0.511866667 0.728812408 1 1 -0.509779463 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 G_33 32 46 HIGH mutated 0.32446535 0.52514638 1 1 -0.694655201 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 G_40 32 46 HIGH mutated 0.874304848 1.508915373 0 1 -0.787303591 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 T_41 32 46 HIGH mutated 0.86953784 2.418513742 0 1 -1.47580002 1 chr18:10530994-10531043 MA0510.1 RFX5 19 Interacting 6.00E-04 G_44 32 46 HIGH mutated 1.278707538 1.858978236 0 1 -0.539823547 1 chr20:4116337-4116386 MA0079.3 SP1 5 Interacting 0.0085 C_38 34 44 MED created 0.858574594 1.410639014 1 1 -0.716333458 1 chr20:4116337-4116386 MA0079.3 SP1 5 Interacting 0.0085 C_39 33 43 MED created 0.864211446 1.376497503 0 1 -0.671545749 1 chr20:4116337-4116386 MA0079.3 SP1 5 Interacting 0.0085 C_32 29 39 MED created 0.571356778 1.129807874 1 0 -0.983613652 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 A_33 29 38 MED mutated 0.826962194 1.437907265 1 1 -0.798077353 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 A_31 29 38 MED mutated 1.441487582 0.667881905 1 1 1.109893476 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 C_29 29 38 MED mutated 0.971373915 1.414806783 0 1 -0.542506389 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 C_34 29 38 MED mutated 0.879959694 1.644087389 0 1 -0.901777637 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 G_37 29 38 MED mutated 0.994765961 1.522355812 0 1 -0.613876544 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 G_30 29 38 MED mutated 0.807486472 1.535763243 1 0 -0.927445828 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 A_36 29 38 MED mutated 0.771376318 1.285882119 1 1 -0.737251633 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 A_29 29 38 MED mutated 0.653781457 1.870356665 1 0 -1.516433044 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 A_37 29 38 MED mutated 0.819403532 1.339359988 1 0 -0.708897759 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 C_39 33 42 MED created 0.864211446 1.376497503 0 1 -0.671545749 1 chr20:4116337-4116386 MA0599.1 KLF5 11 Interacting 0.0333 T_30 29 38 MED mutated 0.740859578 1.359552355 1 0 -0.875859682 1 chr3:128734834-128734883 MA0473.2 ELF1 2 Interacting 0.0486 C_21 16 27 HIGH created 0.560509564 1.333995402 1 1 -1.250942798 1 chr3:128734834-128734883 MA0842.1 NRL 14 Interacting 0 T_18 16 26 HIGH created 0.843115063 0.473839405 1 1 0.831331353 1 chr3:128734834-128734883 MA0842.1 NRL 14 Interacting 0 A_16 16 26 HIGH created 0.981460443 1.490947617 0 1 -0.603227544 1 chr3:128734834-128734883 MA0156.1 FEV 4 Interacting 0.0254 C_21 17 24 HIGH created 0.560509564 1.333995402 1 1 -1.250942798 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 A_29 25 35 HIGH mutated 0.462256827 0.867565481 1 0 -0.908278026 1 chr3:177338065-177338114 MA0156.1 FEV 4 Interacting 0.0254 G_30 27 34 HIGH created 0.595174934 1.55710147 1 1 -1.387477289 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 G_30 25 35 HIGH mutated 0.595174934 1.55710147 1 1 -1.387477289 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 T_29 25 35 HIGH mutated 0.591739977 0.94541179 1 0 -0.675979491 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 T_31 25 35 HIGH mutated 0.655069485 1.203803439 1 1 -0.877879993 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 A_30 25 35 HIGH mutated 0.3865564 0.999796998 1 0 -1.370956273 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 C_31 25 35 HIGH mutated 0.523764867 1.095860209 1 0 -1.065072582 1 chr3:177338065-177338114 MA0079.3 SP1 5 Interacting 0.0085 G_17 11 21 HIGH created 0.895661754 1.506436235 0 1 -0.7501137 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 C_29 25 35 HIGH mutated 0.461387344 1.090046881 1 0 -1.240339849 1 chr3:177338065-177338114 MA0842.1 NRL 14 Interacting 0 T_30 25 35 HIGH mutated 0.413148371 1.008052292 1 0 -1.286838593 1 chr5:110153339-110153388 MA0103.2 ZEB1 5 Interacting 0.0297 G_15 12 20 HIGH created 0.260659141 0.573686926 1 1 -1.138099184 1 chr5:38807880-38807929 MA0473.2 ELF1 2 Interacting 0.0486 C_35 29 40 HIGH created 1.41066448 2.25667413 1 1 -0.677823214 1 chr6:20877893-20877942 MA0103.2 ZEB1 5 Interacting 0.0297 C_21 15 23 HIGH created 0.261233573 0.969853341 1 0 -1.892426283 1 chr8:17028571-17028620 MA0842.1 NRL 14 Interacting 0 G_21 16 26 LOW created 1.715760488 1.176185756 0 1 0.54473225 1 chr8:82695969-82696018 MA0842.1 NRL 14 Interacting 0 T_21 16 26 HIGH mutated 0.933674997 2.361742249 0 1 -1.338859168 1 chr8:82695969-82696018 MA0842.1 NRL 14 Interacting 0 A_21 16 26 HIGH mutated 0.541945426 1.642690545 1 1 -1.599841242 1 chr1:16562648-16562697 MA0522.1 Tcf3 8 Independent 0 A_4 1 11 LOW mutated 1.216613361 1.349686613 1 1 -0.14975371 0 chr1:16562648-16562697 MA0522.1 Tcf3 8 Independent 0 A_7 1 11 LOW mutated 1.247737088 1.298144077 1 1 -0.057136538 0 chr1:16562648-16562697 MA0522.1 Tcf3 8 Independent 0 C_5 1 11 LOW mutated 1.383000561 1.429411525 1 1 -0.047619584 0 chr1:16562648-16562697 MA0138.2 REST 1 Independent 0.0329 A_32 29 49 LOW mutated 0.723577834 0.617988861 1 1 0.227567379 0 chr1:16562648-16562697 MA0522.1 Tcf3 8 Independent 0 T_5 1 11 LOW created 1.200829786 1.317586417 1 1 -0.13386592 0 chr1:16562648-16562697 MA0797.1 TGIF2 2 Independent 0.0376 T_10 1 12 LOW mutated 0.817192492 0.792894923 1 1 0.043546261 0 chr1:16562648-16562697 MA0797.1 TGIF2 2 Independent 0.0376 T_10 1 12 LOW created 0.817192492 0.792894923 1 1 0.043546261 0 chr1:16562648-16562697 MA0522.1 Tcf3 8 Independent 0 T_7 1 11 LOW mutated 2.163584903 1.785373081 1 1 0.277198157 0 chr1:16562648-16562697 MA0824.1 ID4 3 Independent 5.00E-04 T_10 2 11 LOW mutated 0.817192492 0.792894923 1 1 0.043546261 0 chr1:174784353-174784402 MA0103.2 ZEB1 3 Independent 4.00E-04 C_10 10 18 LOW mutated 0.559800385 0.602059221 1 1 -0.104992923 0 chr1:174784353-174784402 MA0080.3 Spi1 3 Independent 5.00E-04 A_20 10 24 LOW mutated 1.778338229 1.772022324 1 1 0.005132963 0 chr1:174784353-174784402 MA0473.1 ELF1 3 Independent 1.00E-04 A_20 11 23 LOW mutated 1.778338229 1.772022324 1 1 0.005132963 0 chr11:67124761-67124810 MA0527.1 ZBTB33 1 Independent 0.0199 G_36 28 42 LOW mutated 0.473339091 0.491727415 1 1 -0.054984716 0 chr11:67124761-67124810 MA0105.1 NFKB1 7 Independent 0 C_12 3 12 LOW mutated 1.762403973 1.489957945 1 1 0.242273043 0 chr11:67124761-67124810 MA0105.1 NFKB1 7 Independent 0 C_12 3 12 LOW mutated 1.762403973 1.489957945 1 1 0.242273043 0 chr14:36347890-36347939 MA0019.1 Ddit3::Cebpa 1 Independent 0.0174 A_43 36 47 MED mutated 0.628493593 0.572297087 1 1 0.135133775 0 chr14:36347890-36347939 MA0522.1 Tcf3 8 Independent 0 C_37 33 43 MED created 0.528560821 0.449398072 1 1 0.234075553 0 chr14:36347890-36347939 MA0824.1 ID4 3 Independent 5.00E-04 C_37 33 42 MED created 0.528560821 0.449398072 1 1 0.234075553 0 chr16:12049767-12049816 MA0914.1 ISL2 3 Independent 0.0096 G_15 13 20 HIGH mutated 1.501870788 1.435077041 1 1 0.065632508 0 chr16:12049767-12049816 MA0914.1 ISL2 3 Independent 0.0096 A_14 13 20 HIGH mutated 1.564988073 1.295303 1 1 0.272862047 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 G_46 41 48 HIGH mutated 1.300942746 1.394519502 1 1 -0.10021064 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 T_42 41 48 HIGH mutated 1.466887638 1.890795609 1 1 -0.366235053 0 chr18:10530994-10531043 MA0519.1 Stat5a::Stat5b 2 Independent 0.0281 A_37 31 41 HIGH mutated 0.771915777 0.774435681 1 1 -0.00470198 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 T_48 41 48 HIGH mutated 1.333052335 1.125227808 1 1 0.244516309 0 chr18:10530994-10531043 MA0510.1 RFX5 6 Independent 0 C_44 32 46 HIGH mutated 1.326611736 1.261831149 1 1 0.072227325 0 chr18:10530994-10531043 MA0510.1 RFX5 6 Independent 0 G_42 32 46 HIGH mutated 1.345103446 1.693713214 1 1 -0.332472485 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 A_48 41 48 HIGH mutated 1.712019436 1.722608202 1 1 -0.008895526 0 chr18:10530994-10531043 MA0698.1 ZBTB18 5 Independent 0.0014 A_5 3 15 HIGH mutated 1.410011572 1.166987493 1 1 0.272917904 0 chr18:10530994-10531043 MA0698.1 ZBTB18 5 Independent 0.0014 C_12 3 15 HIGH mutated 1.407145633 1.343747793 1 1 0.066509263 0 chr18:10530994-10531043 MA0698.1 ZBTB18 5 Independent 0.0014 A_11 3 15 HIGH mutated 1.417982804 1.24865035 1 1 0.18347049 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 G_47 41 48 HIGH mutated 1.292485848 1.223094246 1 1 0.079612909 0 chr18:10530994-10531043 MA0698.1 ZBTB18 5 Independent 0.0014 T_7 3 15 HIGH mutated 1.896421392 1.689696668 1 1 0.166515293 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 A_46 41 48 HIGH mutated 1.327149682 1.175072198 1 1 0.175581693 0 chr18:10530994-10531043 MA0510.1 RFX5 6 Independent 0 T_42 32 46 HIGH created 1.466887638 1.890795609 1 1 -0.366235053 0 chr18:10530994-10531043 MA0510.1 RFX5 6 Independent 0 A_37 32 46 HIGH created 0.771915777 0.774435681 1 1 -0.00470198 0 chr18:10530994-10531043 MA0510.1 RFX5 6 Independent 0 A_46 32 46 HIGH mutated 1.327149682 1.175072198 1 1 0.175581693 0 chr18:10530994-10531043 MA0510.1 RFX5 6 Independent 0 G_46 32 46 HIGH created 1.300942746 1.394519502 1 1 -0.10021064 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 G_42 41 48 HIGH mutated 1.345103446 1.693713214 1 1 -0.332472485 0 chr18:10530994-10531043 MA0461.1 Atoh1 10 Independent 0 C_44 41 48 HIGH created 1.326611736 1.261831149 1 1 0.072227325 0 chr18:51751539-51751588 MA0103.2 ZEB1 3 Independent 4.00E-04 G_43 35 43 LOW created 0.391895831 0.437571428 1 1 -0.159048312 0 chr18:51751539-51751588 MA0105.1 NFKB1 7 Independent 0 C_37 32 41 LOW created 1.518526216 1.342421588 1 1 0.177833994 0 chr18:51751539-51751588 MA0105.1 NFKB1 7 Independent 0 C_38 32 41 LOW created 0.822503612 0.812737695 1 1 0.017232205 0 chr18:51751539-51751588 MA0105.1 NFKB1 7 Independent 0 A_34 32 41 LOW created 0.701165024 0.825305512 1 1 -0.235174244 0 chr18:51751539-51751588 MA0105.1 NFKB1 7 Independent 0 T_32 32 41 LOW mutated 0.801494523 0.8199897 1 1 -0.032913126 0 chr18:51751539-51751588 MA0105.1 NFKB1 7 Independent 0 G_37 32 41 LOW mutated 1.648993611 1.329556348 1 1 0.310640888 0 chr18:51751539-51751588 MA0103.2 ZEB1 3 Independent 4.00E-04 G_30 27 35 LOW mutated 0.537570098 0.697588937 1 1 -0.375924269 0 chr20:40155141-40155190 MA0024.1 E2F1 1 Independent 0.0179 A_36 29 36 LOW mutated 1.560525442 1.880968746 1 1 -0.269443999 0 chr20:40155141-40155190 MA0060.1 NFYA 1 Independent 0.0178 C_32 27 42 LOW created 1.675825654 1.8721781 1 1 -0.15984562 0 chr20:40155141-40155190 MA0060.2 NFYA 1 Independent 0.0178 C_32 28 45 LOW mutated 1.675825654 1.8721781 1 1 -0.15984562 0 chr20:40155141-40155190 MA0473.1 ELF1 3 Independent 1.00E-04 A_41 33 45 LOW created 1.511903114 1.760007544 1 1 -0.219215921 0 chr20:40155141-40155190 MA0140.2 GATA1::TAL1 1 Independent 0.0389 A_14 1 18 LOW mutated 1.743444583 1.816364761 1 1 -0.059113446 0 chr3:128734834-128734883 MA0461.1 Atoh1 10 Independent 0 C_19 17 24 HIGH created 0.872428649 0.779108614 1 1 0.16321268 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 A_8 4 18 HIGH mutated 0.793433136 0.676697917 1 1 0.2295967 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 G_10 4 18 HIGH created 0.838270136 0.808476793 1 1 0.052208871 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 A_10 4 18 HIGH created 0.611675678 0.505658904 1 1 0.274602379 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 C_7 4 18 HIGH created 0.79247626 0.690652266 1 1 0.198408203 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 A_13 4 18 HIGH mutated 0.846843885 0.68214904 1 1 0.312009051 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 G_12 4 18 HIGH mutated 0.852850848 0.772134917 1 1 0.143440501 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 T_12 4 18 HIGH mutated 0.830588863 0.838904359 1 1 -0.014371815 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 G_8 4 18 HIGH mutated 0.821615026 0.750810968 1 1 0.13001284 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 C_13 4 18 HIGH mutated 0.786810095 0.79854394 1 1 -0.021356326 0 chr3:128734834-128734883 MA0098.2 Ets1 10 Independent 0 A_12 4 18 HIGH mutated 0.85392343 0.788047566 1 1 0.115823999 0 chr3:128734834-128734883 MA0522.1 Tcf3 8 Independent 0 G_10 2 12 HIGH mutated 0.838270136 0.808476793 1 1 0.052208871 0 chr3:128734834-128734883 MA0824.1 ID4 3 Independent 5.00E-04 G_10 3 12 HIGH mutated 0.838270136 0.808476793 1 1 0.052208871 0 chr3:177338065-177338114 MA0039.1 Klf4 4 Independent 0.004 G_42 41 50 HIGH mutated 0.785698208 0.775204291 1 1 0.019398715 0 chr3:177338065-177338114 MA0039.1 Klf4 4 Independent 0.004 C_44 41 50 HIGH mutated 1.445116455 1.502875689 1 1 -0.056539924 0 chr3:177338065-177338114 MA0461.1 Atoh1 10 Independent 0 G_32 27 34 HIGH mutated 0.728570551 0.724341608 1 1 0.008398432 0 chr3:177338065-177338114 MA0039.1 Klf4 4 Independent 0.004 T_46 41 50 HIGH mutated 0.653564676 0.736338586 1 1 -0.172039293 0 chr3:177338065-177338114 MA0039.1 Klf4 4 Independent 0.004 C_46 41 50 HIGH mutated 0.793733889 0.769384819 1 1 0.04495004 0 chr4:24475333-24475382 MA0038.1 Gfi1 1 Independent 0.035 T_11 7 16 LOW mutated 0.484957812 0.406386526 1 1 0.255006677 0 chr4:24475333-24475382 MA0052.3 MEF2A 1 Independent 0.0206 T_40 32 43 LOW mutated 0.799280891 0.824839055 1 1 -0.045410046 0 chr4:75585205-75585254 MA0080.3 Spi1 3 Independent 5.00E-04 G_42 34 48 LOW mutated 1.379175466 1.462799876 1 1 -0.084926393 0 chr4:75585205-75585254 MA0050.2 IRF1 2 Independent 0.0196 T_42 30 50 LOW created 1.698990745 1.370250854 1 1 0.310237959 0 chr4:75585205-75585254 MA0050.2 IRF1 2 Independent 0.0196 G_42 30 50 LOW created 1.379175466 1.462799876 1 1 -0.084926393 0 chr5:110153339-110153388 MA0502.1 NFYB 1 Independent 0.0172 G_10 3 17 HIGH mutated 0.659681228 0.758701456 1 1 -0.201763256 0 chr5:110153339-110153388 MA0077.1 SOX9 2 Independent 0.0043 T_11 4 12 HIGH created 0.769111713 0.649270161 1 1 0.244374255 0 chr5:110153339-110153388 MA0914.1 ISL2 3 Independent 0.0096 A_48 42 49 HIGH created 0.76068987 0.704735015 1 1 0.110227497 0 chr5:110153339-110153388 MA0507.1 POU2F2 2 Independent 9.00E-04 A_17 12 24 HIGH created 0.756241806 0.706667259 1 1 0.097816537 0 chr5:110153339-110153388 MA0698.1 ZBTB18 5 Independent 0.0014 A_17 8 20 HIGH created 0.756241806 0.706667259 1 1 0.097816537 0 chr5:110153339-110153388 MA0522.1 Tcf3 8 Independent 0 G_11 9 19 HIGH created 1.190213215 1.246128249 1 1 -0.066232513 0 chr5:110153339-110153388 MA0077.1 SOX9 2 Independent 0.0043 C_4 4 12 HIGH created 0.564411603 0.45249378 1 1 0.318849686 0 chr5:38807880-38807929 MA0507.1 POU2F2 2 Independent 9.00E-04 T_5 2 14 HIGH mutated 0.55414645 0.654430144 1 1 -0.2399719 0 chr5:38807880-38807929 MA0517.1 STAT1::STAT2 7 Independent 0 G_9 5 19 HIGH mutated 0.642337018 0.693013847 1 1 -0.109553738 0 chr5:38807880-38807929 MA0517.1 STAT1::STAT2 7 Independent 0 C_8 5 19 HIGH mutated 0.476249931 0.625938382 1 1 -0.394301759 0 chr5:38807880-38807929 MA0517.1 STAT1::STAT2 7 Independent 0 C_6 5 19 HIGH mutated 0.517591954 0.643399157 1 1 -0.313898856 0 chr5:38807880-38807929 MA0517.1 STAT1::STAT2 7 Independent 0 C_5 5 19 HIGH mutated 0.658610534 0.717375639 1 1 -0.123303169 0 chr5:38807880-38807929 MA0517.1 STAT1::STAT2 7 Independent 0 C_7 5 19 HIGH mutated 0.494181225 0.612062207 1 1 -0.308638088 0 chr5:38807880-38807929 MA0517.1 STAT1::STAT2 7 Independent 0 T_5 5 19 HIGH mutated 0.55414645 0.654430144 1 1 -0.2399719 0 chr5:38807880-38807929 MA0517.1 STAT1::STAT2 7 Independent 0 A_6 5 19 HIGH mutated 0.593348697 0.67360285 1 1 -0.18301805 0 chr6:116567437-116567486 MA0041.1 Foxd3 2 Independent 0.001 C_44 35 46 LOW created 1.962712078 1.805421538 1 1 0.120512827 0 chr6:116567437-116567486 MA0041.1 Foxd3 2 Independent 0.001 A_44 35 46 LOW created 1.338876345 1.370943345 1 1 -0.034146229 0 chr6:116567437-116567486 MA0498.2 MEIS1 1 Independent 0.0393 A_45 42 48 LOW created 0.808352088 0.740623899 1 1 0.12624271 0 chr6:116567437-116567486 MA0519.1 Stat5a::Stat5b 2 Independent 0.0281 C_44 40 50 LOW created 1.962712078 1.805421538 1 1 0.120512827 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 C_41 39 49 HIGH created 0.861646825 0.836229747 1 1 0.043197288 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 C_43 39 49 HIGH mutated 0.549419028 0.470165158 1 1 0.224739246 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 A_42 39 49 HIGH mutated 0.765601281 0.763363443 1 1 0.004223145 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 C_42 39 49 HIGH mutated 0.757163439 0.646858112 1 1 0.227155456 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 A_45 39 49 HIGH mutated 0.763443963 0.717505741 1 1 0.08953189 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 G_43 39 49 HIGH mutated 0.744069886 0.691491659 1 1 0.105726284 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 T_43 39 49 HIGH mutated 0.717340356 0.66186559 1 1 0.116119526 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 A_44 39 49 HIGH mutated 0.806404726 0.770947941 1 1 0.06487065 0 chr6:16043180-16043229 MA0724.1 VENTX 1 Independent 0.0164 T_15 14 22 HIGH created 0.679544131 0.79848029 1 1 -0.23268955 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 A_47 39 49 HIGH mutated 0.736621919 0.762887259 1 1 -0.050545543 0 chr6:16043180-16043229 MA0594.1 Hoxa9 3 Independent 0 T_15 11 21 HIGH mutated 0.679544131 0.79848029 1 1 -0.23268955 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 T_44 39 49 HIGH created 0.772452789 0.648745097 1 1 0.25179503 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 T_45 39 49 HIGH mutated 0.651661903 0.552032507 1 1 0.239370432 0 chr6:16043180-16043229 MA0852.1 Foxk1 1 Independent 0.0372 A_12 4 20 HIGH created 0.528317899 0.657178929 1 1 -0.314879936 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 A_46 39 49 HIGH mutated 0.692538828 0.648691706 1 1 0.094361968 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 A_41 39 49 HIGH mutated 0.740423762 0.684174915 1 1 0.113985988 0 chr6:16043180-16043229 MA0597.1 THAP1 3 Independent 0.0112 T_34 32 40 HIGH created 0.686272958 0.591582577 1 1 0.214202946 0 chr6:16043180-16043229 MA0594.1 Hoxa9 3 Independent 0 G_16 11 21 HIGH created 0.700850969 0.623184229 1 1 0.169448974 0 chr6:16043180-16043229 MA0594.1 Hoxa9 3 Independent 0 T_16 11 21 HIGH mutated 0.652230745 0.777091934 1 1 -0.252702837 0 chr6:16043180-16043229 MA0597.1 THAP1 3 Independent 0.0112 T_39 32 40 HIGH mutated 0.752392195 0.796738021 1 1 -0.082620539 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 G_47 39 49 HIGH mutated 0.8031279 0.672902364 1 1 0.255232568 0 chr6:16043180-16043229 MA0512.1 Rxra 16 Independent 0 G_41 39 49 HIGH mutated 0.702430667 0.628134328 1 1 0.161282716 0 chr6:16043180-16043229 MA0597.1 THAP1 3 Independent 0.0112 C_35 32 40 HIGH mutated 1.230279399 1.220810968 1 1 0.011146163 0 chr6:20877893-20877942 MA0080.3 Spi1 3 Independent 5.00E-04 C_9 3 17 HIGH mutated 0.621768471 0.6870468 1 1 -0.144030914 0 chr6:20877893-20877942 MA0473.1 ELF1 3 Independent 1.00E-04 C_9 4 16 HIGH mutated 0.621768471 0.6870468 1 1 -0.144030914 0 chr8:17028571-17028620 MA0512.1 Rxra 16 Independent 0 G_38 32 42 LOW created 1.46772833 1.401999439 1 1 0.066099185 0