Supplemental Table S12											
											
# Single-exon dataset functional enrichment											
# P-value - uncorrected P value											
# P-value adjusted - P value corrected for 40 tests in human and 38 tests in mouse (Benjamini-Hochberg method)											
											
											
											
											
											
Species	GO Term	Description	P-value	P-value adjusted	Enrichment						
Human	GO:0050907	detection of chemical stimulus involved in sensory perception	2.01E-204	8.04E-203	32.71						
Human	GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.92E-196	3.84E-195	36.09						
Human	GO:0009593	detection of chemical stimulus	1.62E-193	2.16E-192	29.68						
Human	GO:0050906	detection of stimulus involved in sensory perception	1.52E-186	1.52E-185	27.73						
Human	GO:0051606	detection of stimulus	3.21E-157	2.57E-156	19.86						
Human	GO:0007186	G-protein coupled receptor signaling pathway	1.28E-124	8.53E-124	10.23						
Human	GO:0007608	sensory perception of smell	2.08E-59	1.19E-58	27.57						
Human	GO:0007606	sensory perception of chemical stimulus	1.27E-54	6.35E-54	20.93						
Human	GO:0007165	signal transduction	5.13E-35	2.28E-34	2.38						
Human	GO:0031424	keratinization	7.92E-33	3.17E-32	13.76						
Human	GO:0050896	response to stimulus	4.01E-28	1.46E-27	2.24						
Human	GO:0007600	sensory perception	1.39E-24	4.63E-24	5.87						
Human	GO:0050877	neurological system process	2.89E-16	8.89E-16	3.78						
Human	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	4.66E-14	1.33E-13	20.95						
Human	GO:0050912	detection of chemical stimulus involved in sensory perception of taste	5.48E-13	1.46E-12	17.85						
Human	GO:0032501	multicellular organismal process	4.00E-12	1.00E-11	1.93						
Human	GO:0002323	natural killer cell activation involved in immune response	4.29E-11	1.01E-10	35.14						
Human	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	6.16E-10	1.30E-09	28.11						
Human	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein	6.16E-10	1.30E-09	28.11						
Human	GO:0003008	system process	2.16E-09	4.32E-09	2.47						
Human	GO:0030101	natural killer cell activation	1.38E-07	2.51E-07	15.62						
Human	GO:0042100	B cell proliferation	1.38E-07	2.51E-07	15.62						
Human	GO:0007192	adenylate cyclase-activating serotonin receptor signaling pathway	3.76E-07	6.54E-07	40.16						
Human	GO:0043330	response to exogenous dsRNA	6.77E-07	1.13E-06	12.78						
Human	GO:0060338	regulation of type I interferon-mediated signaling pathway	9.32E-07	1.49E-06	16.06						
Human	GO:0043331	response to dsRNA	1.32E-06	2.03E-06	11.71						
Human	GO:0050794	regulation of cellular process	1.47E-06	2.18E-06	1.25						
Human	GO:0002286	T cell activation involved in immune response	5.34E-06	7.63E-06	9.69						
Human	GO:0046651	lymphocyte proliferation	2.97E-05	4.10E-05	7.6						
Human	GO:0032943	mononuclear cell proliferation	3.56E-05	4.75E-05	7.4						
Human	GO:0030183	B cell differentiation	5.05E-05	6.52E-05	7.03						
Human	GO:0050789	regulation of biological process	5.32E-05	6.65E-05	1.2						
Human	GO:0070661	leukocyte proliferation	5.96E-05	7.22E-05	6.86						
Human	GO:0060337	type I interferon signaling pathway	6.59E-05	7.75E-05	8.31						
Human	GO:0002285	lymphocyte activation involved in immune response	1.10E-04	1.26E-04	6.25						
Human	GO:0007210	serotonin receptor signaling pathway	1.59E-04	1.77E-04	13.39						
Human	GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.68E-04	1.82E-04	5.86						
Human	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	2.25E-04	2.37E-04	12.36						
Human	GO:0034728	nucleosome organization	7.17E-04	7.35E-04	5.48						
Human	GO:0006334	nucleosome assembly	9.20E-04	9.20E-04	6.48						
Mouse	GO:0003008	system process	0.00E+00	0.00E+00	6.71						
Mouse	GO:0050877	neurological system process	0.00E+00	0.00E+00	8.42						
Mouse	GO:0007186	G-protein coupled receptor signaling pathway	0.00E+00	0.00E+00	8.76						
Mouse	GO:0007608	sensory perception of smell	0.00E+00	0.00E+00	15.52						
Mouse	GO:0007606	sensory perception of chemical stimulus	0.00E+00	0.00E+00	15.32						
Mouse	GO:0007600	sensory perception	0.00E+00	0.00E+00	10.72						
Mouse	GO:0032501	multicellular organismal process	2.02E-185	1.10E-184	3.34						
Mouse	GO:0007165	signal transduction	2.58E-146	1.23E-145	3.05						
Mouse	GO:0050907	detection of chemical stimulus involved in sensory perception	3.32E-109	1.40E-108	14.08						
Mouse	GO:0009593	detection of chemical stimulus	6.35E-101	2.41E-100	12.68						
Mouse	GO:0050906	detection of stimulus involved in sensory perception	2.60E-89	8.98E-89	10.73						
Mouse	GO:0051606	detection of stimulus	3.25E-74	1.03E-73	8.38						
Mouse	GO:0019236	response to pheromone	2.16E-44	6.31E-44	17.37						
Mouse	GO:0050794	regulation of cellular process	4.40E-32	1.19E-31	1.44						
Mouse	GO:0050789	regulation of biological process	3.89E-25	9.85E-25	1.36						
Mouse	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	8.42E-22	2.00E-21	13.33						
Mouse	GO:0050912	detection of chemical stimulus involved in sensory perception of taste	1.97E-20	4.40E-20	12.15						
Mouse	GO:0065007	biological regulation	5.37E-19	1.13E-18	1.29						
Mouse	GO:0050909	sensory perception of taste	2.39E-16	4.78E-16	9.39						
Mouse	GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.02E-11	1.94E-11	15.65						
Mouse	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	6.19E-10	1.07E-09	14.08						
Mouse	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein	6.19E-10	1.07E-09	14.08						
Mouse	GO:0002323	natural killer cell activation involved in immune response	1.22E-08	2.02E-08	11.27						
Mouse	GO:0007192	adenylate cyclase-activating serotonin receptor signaling pathway	2.23E-08	3.53E-08	18.78						
Mouse	GO:0009987	cellular process	4.12E-07	6.26E-07	1.13						
Mouse	GO:0050896	response to stimulus	6.35E-07	9.28E-07	1.37						
Mouse	GO:0042100	B cell proliferation	1.35E-06	1.90E-06	7.35						
Mouse	GO:0030101	natural killer cell activation	2.06E-06	2.80E-06	7.04						
Mouse	GO:0043330	response to exogenous dsRNA	1.24E-05	1.62E-05	5.83						
Mouse	GO:0007210	serotonin receptor signaling pathway	1.56E-05	1.98E-05	9.39						
Mouse	GO:0043331	response to dsRNA	2.27E-05	2.78E-05	5.45						
Mouse	GO:0002286	T cell activation involved in immune response	5.12E-05	6.08E-05	4.97						
Mouse	GO:0006334	nucleosome assembly	9.77E-05	1.13E-04	5.18						
Mouse	GO:0034728	nucleosome organization	4.30E-04	4.81E-04	3.84						
Mouse	GO:0032943	mononuclear cell proliferation	5.12E-04	5.40E-04	3.76						
Mouse	GO:0046651	lymphocyte proliferation	5.12E-04	5.40E-04	3.76						
Mouse	GO:0070661	leukocyte proliferation	7.16E-04	7.35E-04	3.6						
Mouse	GO:0030183	B cell differentiation	7.59E-04	7.59E-04	3.29