Before	Ref	After	Var	COSMIC.1	COSMIC.2	COSMIC.3	COSMIC.4	COSMIC.5	COSMIC.6	COSMIC.7	COSMIC.8	COSMIC.9	COSMIC.10	COSMIC.11	COSMIC.12	COSMIC.13	COSMIC.14	COSMIC.15	COSMIC.16	COSMIC.17	COSMIC.18	COSMIC.19	COSMIC.20	COSMIC.21	COSMIC.22	COSMIC.23	COSMIC.24	COSMIC.25	COSMIC.26	COSMIC.27	COSMIC.28	COSMIC.29	COSMIC.30
A	C	A	A	0.011098326166	0.000682708227	0.022172306775	0.0365	0.014941547714	0.0017	0.0004	0.036718003777	0.012	0.0007	0.0002	0.0077	0.000334757187	0.0001	0.0013	0.0161	0.001832019172	0.050536418624999996	0.0107	0.001179961596	0.0001	0.0015040703750000002	0.00045336068299999996	0.028645992536	0.009896768001	0.00203977291	0.005205626909	0.001397438842	0.06998198728	0.0
A	C	C	A	0.009149340734	0.000619107232	0.017871675353	0.0309	0.008960917997	0.0028	0.0005	0.033245722246	0.0067	0.001	0.001	0.0047	0.000648736139	0.0042	0.004	0.0097	0.000342235622	0.010939824789	0.0074	0.002211505148	0.0007	0.002451011015	0.000366800484	0.020214638433	0.00699892877	0.001487162284	0.004738227415	0.000917187665	0.055152357207000006	0.0
A	C	G	A	0.001490070468	9.9278956e-05	0.002138339617	0.0183	0.0022078460120000002	0.0005	0.0	0.002525311256	0.0005	0.0003	0.0	0.0017	3.8144594000000004e-05	0.0005	0.0	0.0022	1.576225e-06	0.002288072697	0.0005	1.6169100000000001e-07	0.0	0.0	0.0	0.020478996484999998	0.001448442998	0.000283945614	0.000782697937	0.0	0.017846984044	0.0019673
A	C	T	A	0.006233885236	0.000323891363	0.01626514559	0.0243	0.009206905292	0.0019	0.0004	0.033598549516	0.0068	0.0092	0.0002	0.0046	0.00084665846	0.0296	0.0057	0.0088	0.0031796647720000004	0.019424091364	0.0074	0.003008009987	0.0006	0.000922452518	0.0	0.024600145425	0.004966565004	0.000597865638	0.0027182424550000004	0.000513409971	0.026804715973	0.0
C	C	A	A	0.006595870109	0.000677444988	0.018781725573	0.0461	0.00967490433	0.0101	0.0012	0.03172375659	0.0098	0.0031	0.0007	0.0135	0.001710089561	0.0056	0.0106	0.0159	0.001032430218	0.08876810881899999	0.0112	0.017377110647	0.002	0.004549692944	0.000164739382	0.06355928379300001	0.014832947875	0.003705850083	0.005065073268	0.001168515637	0.051410211701	0.0
C	C	C	A	0.0073423678150000005	0.000213681013	0.015760457842	0.0614	0.004952300642	0.0241	0.0006	0.025505407135	0.0057	0.0009	0.0017	0.0112	0.001159256581	0.0102	0.0084	0.01	0.000421880127	0.020641390557	0.0159	0.036502462984	0.0014	0.0037644738540000004	0.000736874802	0.033757004715999996	0.007822175302	0.003980723373	0.002234153344	0.00033429181100000003	0.025825650831	0.0
C	C	G	A	0.0008928403699999999	6.77046e-06	0.001963389846	0.0088	0.002800627307	0.0091	0.0	0.001159624303	0.0	0.0007	0.001	0.0028	0.000244166533	0.0009	0.0015	0.0022	0.000297462769	0.01717840248	0.0018	0.012482587542	0.0027	0.000900163331	0.00016395366099999998	0.022428985806	0.001276976732	0.00081174197	0.000266312161	5.3651998e-05	0.014496183324	0.0022624
C	C	T	A	0.007186581642	0.000416332906	0.014722861126	0.0432	0.011013465824	0.0571	0.0013	0.028791172971	0.0091	0.016	0.0014	0.0071	0.001256768244	0.1257	0.0228	0.0084	3.1479429e-05	0.037676958929	0.0096	0.103401226249	0.0056	0.004439846231	0.000722731835	0.020086515438	0.012563654719	0.019038431345	0.003100570009	0.00018667190200000002	0.040355074099	0.0
G	C	A	A	0.008232603989	0.000352013353	0.009696539676	0.0376	0.011892168978999999	0.0024	0.0003	0.023682328869	0.0118	0.0014	0.0004	0.0062	0.000132109643	0.0018	0.0024	0.0096	0.006535404875	0.12872415808	0.0032	0.001116123789	0.0001	0.0012983701609999999	0.00034990749499999997	0.054676448679	0.013465295053	0.001375311846	0.010755871858000001	0.0021366290770000003	0.078046610108	0.008853
G	C	C	A	0.0057580214099999995	0.00013381687900000002	0.010843341115999999	0.0399	0.009247857495000001	0.0058	0.0001	0.015821896445	0.0092	0.0022	0.001	0.0056	0.000754244011	0.0114	0.0099	0.0094	0.001293803953	0.016092878663	0.0031	0.003271428605	0.0038	0.0018096221520000001	0.000568337772	0.109945988997	0.006468298058	0.001961639088	0.012442335116999999	0.000429208379	0.07346091466900001	0.0093449
G	C	G	A	0.000616335232	0.00017844166000000001	0.000929140538	0.0227	0.002809188466	0.0021	0.0	0.000850913754	0.0	0.0002	0.0	0.0015	9.682077499999999e-05	0.0011	0.0013	0.0036	0.001283663378	0.009271416762	0.0	0.003751612508	0.0003	0.00033383805500000004	0.000149417834	0.04652486901	0.000658103089	1.3229664e-05	0.001629628347	0.0	0.017383296915	0.0008853
G	C	T	A	0.004459080311	0.000122832046	0.012215382638999999	0.0258	0.010301267456000001	0.0087	0.0001	0.021061235802000002	0.0085	0.0088	0.0006	0.0027	0.000551103672	0.0736	0.0309	0.0063	0.0031037666720000003	0.072017070126	0.0072	0.01293719445	0.0023	0.000519148161	0.0	0.050428709482000005	0.010473080346999999	0.001934996293	0.007412355152	0.001318507256	0.059602472117999995	0.0081645
T	C	A	A	0.012250063666	0.015127427519	0.011653224909	0.033	0.014774016248000002	0.0017	0.001	0.027032383039	0.0222	0.0374	0.0009	0.0066	0.048166047937	0.0005	0.0057	0.0122	0.0018245582569999998	0.067080643529	0.0051	0.000688299692	0.0001	0.0040516345520000005	0.002071289985	0.031451263182	0.006938146585	0.002680062424	0.0070792845220000004	0.000775902768	0.026894406511	0.0
T	C	C	A	0.011162229328999998	0.006532492454	0.016606775011	0.0538	0.012043464964	0.0029	0.002	0.01808977329	0.0043	0.0103	0.0025	0.0099	0.017329557089	0.0166	0.0062	0.0145	0.001286518338	0.041869009693	0.0063	0.00405822906	0.0005	0.0027397709370000005	0.0006964102009999999	0.062538293699	0.0102466074	0.002031643866	0.006268800628	0.000829292467	0.031608136996	0.0
T	C	G	A	0.002275495686	0.001656455398	0.001357239439	0.0104	0.003902362388	0.0011	0.0002	0.001694875197	0.0	0.0031	0.0001	0.0019	0.002293157306	0.0	0.0025	0.004	0.002172941968	0.01516237929	0.0018	0.001001102231	0.0	0.00051315107	9.939363300000001e-05	0.012802590728	0.0	0.0002650717	0.001446403415	0.0	0.012500468152	0.0016722
T	C	T	A	0.015259102491	0.012394610714	0.016328075975	0.037	0.018243395705	0.0058	0.0013	0.038141330868	0.0322	0.3083	0.0004	0.0049	0.018634581512	0.0516	0.0145	0.0157	0.0050123163939999995	0.117877846666	0.0087	0.012229104506999999	0.0004	0.003605650899	0.000207430191	0.030297679613000002	0.024625787226	0.003017187457	0.00980627775	0.0019980736670000003	0.04120717639	0.0
A	C	A	G	0.001801068369	0.000263481044	0.024002615202	0.0097	0.011671021651	0.0013	0.0	0.008356844806	0.0048	0.0005	0.0007	0.0031	0.003775165298	0.0001	0.0011	0.0048	0.0016617041949999998	0.00151688758	0.0058	0.0006970410700000001	0.0005	0.00052764404	0.0	0.011993038821	0.008032567646	0.0012728812970000001	0.0013241632459999998	0.000255194996	0.009301971097000001	0.0
A	C	C	G	0.0025809085200000003	0.000269866049	0.012160303668	0.0054	0.007292088582999999	0.0012	0.0	0.004306380304	0.0023	0.0003	0.0003	0.0015	0.0009208248279999999	0.0	0.0001	0.0024	0.0016268983989999998	0.002498784527	0.0019	0.002059310006	0.0008	0.0	0.0	0.008425119791999999	0.0016359704130000001	0.001528194862	0.001771084129	0.000268898964	0.0034790488709999998	0.0
A	C	G	G	0.0005925480219999999	0.000219233911	0.005275419458	0.0031	0.002303839151	0.0	0.0	0.000584415303	0.0	0.0	0.0	0.0	1.9890489e-05	0.0	0.0006	0.0	2.5801897e-05	0.002614508983	0.0	1.2734958e-05	0.0	0.0	0.0	0.0	0.0	0.00030724630799999997	0.0	0.0	0.00015443352300000001	0.00482
A	C	T	G	0.002963986287	0.000610973492	0.023277656342000002	0.0054	0.011696245747	0.0018	0.0001	0.008634906912	0.0038	0.0002	0.0009	0.0025	0.003860632488	0.0001	0.001	0.0073	0.001328507581	0.00398301117	0.0072	0.0008485871159999999	0.0018	0.000299454735	0.0	0.003881383185	0.003428449701	0.002498251826	0.0013227198190000002	0.000307698016	0.003976789927	0.0
C	C	A	G	0.001284983446	2.7772077e-05	0.016832571989	0.0105	0.007537523174000001	0.0	0.0001	0.006619077216	0.0018	0.0	0.0	0.0019	0.005333651375	0.0	0.0009	0.004	0.001924978751	0.000458463822	0.0002	1.331626e-05	0.0001	0.0005820176630000001	0.00019904917399999998	0.013476821609	0.0072007904099999995	0.001279106069	0.004730649426	0.00010336609200000001	0.002618863169	0.0
C	C	C	G	0.000702134818	0.000279643862	0.013531441527	0.0097	0.007633226665	0.0	0.0004	0.006077702894999999	0.002	0.0	0.0002	0.0019	0.000912303471	0.0	0.0003	0.005	0.0007093677740000001	0.00365422833	0.0028	0.0005481447080000001	0.0	0.000825299647	0.00028377602599999997	0.016105687737	0.0045984731170000005	0.001214977303	0.001261644842	0.000144310792	0.00111151227	0.0
C	C	G	G	0.000506289594	1.9161576e-05	0.004176457524	0.0063	0.002613760399	0.0	0.0006	0.0006560334329999999	0.0	0.0	0.0008	0.0	0.000285467331	0.0	0.0004	0.0028	3.517869e-06	0.005405774245	0.0002	0.0	0.0	0.00038211463600000003	0.0	0.000797471998	0.000823709283	0.000207832588	0.000360856587	0.0	0.00152004695	0.0032461
C	C	T	G	0.001381542722	0.000312781573	0.024046390424000003	0.0094	0.009417097876000001	0.0002	0.0003	0.007805026957000001	0.0039	0.0	0.0002	0.0019	0.006383097567999999	0.0	0.0017	0.008	0.0009537763340000001	0.005519604819999999	0.0008	0.00012073055599999999	0.0003	0.001760645911	0.000195775338	0.010388665881999999	0.000196360325	0.0022970262109999998	0.00026802623	0.000290999509	0.000139750691	0.0
G	C	A	G	0.0006021227109999999	4.483851399999999e-05	0.011916844569000001	0.007	0.005559423088999999	0.0	0.0	0.0037245679460000004	0.0011	0.0	0.0	0.0012	0.001349419584	0.0002	0.0022	0.0031	0.001296324191	0.000923879703	0.002	0.001339769321	0.0004	0.0	0.0	0.004945060708	0.004169655524	0.001320607475	0.0014181663870000002	8.1591411e-05	0.000265759858	0.0073775
G	C	C	G	0.0023933522089999997	1.4520103e-05	0.009823653397	0.0091	0.005388801221000001	0.003	0.0004	0.003046596953	0.0029	0.0002	0.0002	0.0011	0.000788807743	0.0001	0.0005	0.0032	0.000260760911	0.000648647922	0.0	0.0018111514749999998	0.0042	0.0	0.000137501074	0.009369875774	0.002392804944	0.001845501071	0.0013467167819999999	0.000105219031	0.000945012884	0.0065906
G	C	G	G	2.48534e-07	4.0665889e-05	0.0016710542499999998	0.0062	0.001100589633	0.0	0.0	0.000321212793	0.0	0.0	0.0	0.0	8.1791214e-05	0.0	0.0006	0.0	4.377552e-06	0.000542839968	0.0	6.37538e-07	0.0	0.000214695851	0.0	0.00562572654	0.00041819391600000005	0.000205060777	0.0	0.0	0.0	0.0015739
G	C	T	G	0.0008900807309999999	0.000268429459	0.017914334306	0.006	0.006041247837	0.0017	0.0	0.005775663598	0.0044	0.0004	0.0	0.0009	0.002680123244	0.0003	0.0018	0.0029	0.001820392786	0.0013767248879999999	0.0	0.001238264182	0.0004	0.000538438803	0.0	0.003055770064	0.001994012217	0.001225532856	0.0045606859740000005	0.000159679354	0.004796744744	0.0
T	C	A	G	0.001874853199	0.037241853149	0.016041405438000002	0.0032	0.002681056961	0.0	0.0002	0.004117878837	0.0033	0.0	0.0001	0.0024	0.280234946548	0.0	0.0009	0.005	0.000392684657	0.001802969051	0.0005	2.4298469e-05	0.0002	0.000225490615	0.000230608944	0.010220857436	0.009798724566999999	0.004201896751	0.0028704337209999996	0.000521370368	0.000820444889	0.0
T	C	C	G	0.002067418791	1.9413411e-05	0.020149920428	0.0105	0.007924048307000001	0.0002	0.001	0.003799649592	0.0025	0.0	0.0011	0.0027	0.06388528658699999	0.0	0.0026	0.0064	0.000655602418	0.007863006794	0.0011	0.00015199855	0.0003	0.00062869502	0.000165787009	0.007578365252	0.0032665071500000004	0.0028077615340000002	0.0031079675689999996	0.0006673258900000001	0.00044411928699999997	0.0
T	C	G	G	0.00030489700400000003	0.0016254654569999999	0.002527910936	0.0031	0.001319075649	0.0	0.0003	2.5653018000000002e-05	0.0	0.0	0.0003	0.0	0.009528486008000001	0.0	0.0	0.0	1.3641541e-05	0.0015132233340000001	0.0	0.0	0.0	0.000395807994	0.0	0.001592714217	0.002057436753	6.197e-09	1.2810409e-05	0.0	0.000143297155	0.0019673
T	C	T	G	0.0031515744599999998	0.066879899684	0.032673640762	0.005	0.0066445957079999994	0.0001	0.0007	0.006247553737999999	0.0049	0.0001	0.0008	0.0015	0.330225481745	0.0001	0.0015	0.0169	0.002852380395	0.0035671020649999997	0.0105	0.0006830599760000001	0.0003	0.000257375147	0.000438955809	0.00610072719	0.01640091685	0.008019382986	0.0021305875030000004	0.001245779535	0.0013698690470000002	0.0
A	C	A	T	0.029514532745	0.007441556817	0.017872170732	0.012	0.021839187574	0.0312	0.0	0.018066687156	0.0093	0.0	0.0225	0.0121	0.001480180764	0.0293	0.0117	0.0135	0.009350488403	0.003825623912	0.0221	0.032858047272	0.0051	0.003113389695	0.019767154372	0.006315518136	0.020987618053	0.0059072320389999995	0.013723285787	0.005433792471	0.005197221326	0.065119
A	C	C	T	0.014322747041	0.002726312428	0.008896034323	0.0075	0.012756105637999999	0.0163	0.0197	0.005650015029	0.0056	0.0032	0.1099	0.0054	4.0508707e-05	0.0321	0.0169	0.0076	0.004224289013	0.002465214261	0.0203	0.022196046913	0.0062	0.0015248602900000002	0.081880579925	0.003844326917	0.013141283697	0.010626457816	0.005424306001000001	0.001815415488	0.00897646999	0.054397
A	C	G	T	0.171646931305	0.0033220832809999997	0.0035727083500000003	0.0028	0.016760177116	0.0908	0.0001	0.019265105464999998	0.0125	0.0126	0.0072	0.0019	0.00031659467100000004	0.0496	0.0309	0.0035	0.009229213313	0.008463956886	0.0368	0.034572014703000004	0.0256	0.003625641201	0.009248715085	0.003110664425	0.019659894285	0.019930323239	0.006706429454	0.0054320393310000005	0.03163899636	0.0204604
A	C	T	T	0.012623763151	0.003326528417	0.014797612209000001	0.0059	0.016477954692	0.0149	0.0043	0.020805967497000002	0.0076	0.0047	0.0639	0.0067	0.0	0.0277	0.0066	0.0101	0.005735961173	0.0056057399269999995	0.0266	0.018819559611	0.003	0.0	0.033209652209000004	0.0034204186729999996	0.005728519312	0.011334530552	0.004475614034	0.0016292131890000001	0.004769666594	0.0219359
C	C	A	T	0.020896446965	0.015019506931	0.014395059491000001	0.021	0.022769209355	0.0085	0.0754	0.004865810020999999	0.0098	0.0012	0.031	0.0187	0.003647278451	0.006	0.0051	0.021	0.021265205902	0.009767511474999999	0.0438	0.011145185306	0.0034	0.007731349522000001	0.060572627805	0.0060354473939999995	0.014333994691000001	0.006594444885	0.017438484778	0.0043915325540000005	0.009126471766999999	0.0694472
C	C	C	T	0.01850170477	0.003516918098	0.008544781191999999	0.0144	0.017509476305	0.0099	0.1007	0.0039801504310000005	0.0069	0.0024	0.1518	0.0094	0.001004229295	0.0167	0.0088	0.0098	0.003847235312	0.0056548284620000005	0.0753	0.018152746865999998	0.0091	0.007110850526000001	0.186375634076	0.0	0.005936643659	0.006510631971	0.007144870207	0.002647660966	0.007067603037000001	0.0638403
C	C	G	T	0.095577217268	0.004979275715	0.00351846584	0.0076	0.012862237589	0.0901	0.0208	0.008338639182	0.0076	0.0109	0.0135	0.0046	0.000129202148	0.0293	0.0155	0.0016	0.013176112314	0.016183222964000002	0.0238	0.044384942487000006	0.0318	0.005502030965	0.015149082593000001	0.0029244190740000003	0.011559391627	0.011904935323999999	0.007503561655	0.002284563551	0.019875180409	0.0173126
C	C	T	T	0.017113307642	0.008956552775	0.016075545711999997	0.0201	0.020429513385	0.0087	0.0788	0.018843627434	0.0097	0.0043	0.0816	0.0205	0.00061176997	0.0186	0.0096	0.0211	0.009648025316	0.005153318613	0.1159	0.013847136214000001	0.004	0.004169777241	0.15601539697699998	0.003971201575	0.013632596884999999	0.006238556326999999	0.007148027702	0.002423984267	0.001634058687	0.0342318
G	C	A	T	0.024943814154	0.006390807876	0.016127273332	0.0087	0.020038258644999998	0.0653	0.0	0.0022612626860000003	0.0062	0.0	0.0261	0.0124	0.002934137577	0.0557	0.0476	0.0125	0.002068754725	0.002703068727	0.0374	0.056793947984999996	0.0163	0.001915370854	0.053282058965	0.023679051295	0.010038112012999999	0.009606515026999999	0.014215313743	0.003384240869	0.011638793032	0.0485934
G	C	C	T	0.027161494035	0.001995816784	0.008208632436999999	0.008	0.018022312238	0.0773	0.021	0.001616649187	0.0069	0.0134	0.0975	0.0092	0.002515171146	0.0618	0.1345	0.0092	0.000325483399	0.004199307536	0.0614	0.05442985727	0.0392	0.0032291335470000003	0.162918343743	0.015919201839999998	0.006953875155	0.019507426720000002	0.020143646182	0.0016874140289999998	0.003781751661	0.0494787
G	C	G	T	0.103570762296	0.000303020977	0.001212922866	0.0023	0.013193817648	0.1339	0.0002	0.0116067116	0.0088	0.027	0.009	0.0023	0.00320526455	0.0978	0.1829	0.0009	0.007511101358	0.011897360825	0.0278	0.004592688609	0.0019	0.0033005988789999996	0.013046494744	0.012648077605999999	0.010468363027	0.022502717382999998	0.009368468496	0.00218930896	0.019684388045	0.0157387
G	C	T	T	0.017689854381	0.003265818188	0.010611649208	0.0082	0.019502915335	0.0524	0.0161	0.006284928996	0.0101	0.0152	0.0522	0.0115	0.001687730545	0.0555	0.08	0.0116	0.000925697167	0.001913380905	0.0917	0.049580863753000005	0.0166	0.00111405957	0.107590399754	0.018129778378000002	0.009823820735	0.017307472184	0.00758962595	0.001043993631	0.0057613368229999995	0.0188865
T	C	A	T	0.014492099634	0.419941399594	0.008880209061	0.0035	0.010997560323999999	0.0074	0.1202	0.007180668540000001	0.005	0.0037	0.0302	0.0138	0.113842093163	0.0092	0.0112	0.0172	0.016100784572	0.014923391701	0.0218	0.01071032207	0.0064	0.0020167216880000003	0.014558613696	0.026571894345999998	0.0110775208	0.011303288768	0.018757776458999998	0.007622257672	0.012076583097999999	0.0849892
T	C	C	T	0.017680775357	0.081972496144	0.013529572798	0.007	0.020644964802999998	0.0067	0.2887	0.004061032938	0.0084	0.0211	0.1589	0.0095	0.015024839001	0.0283	0.0156	0.0131	0.016779984064	0.00996274431	0.033	0.008175509769999999	0.0086	0.001990834246	0.043510446939000004	0.012055691081999999	0.00644878754	0.010807526975	0.007989184405999999	0.005116619241	0.0	0.090301
T	C	G	T	0.076002221712	0.047720186368	0.0017054088579999999	0.0011	0.0075344895739999996	0.0391	0.0992	0.00553512152	0.0047	0.2141	0.008	0.001	0.0061020979559999996	0.0094	0.0104	0.0036	0.016272095596	0.011549715126	0.009	0.023163899202000002	0.0126	0.0014984730910000002	0.002752640544	0.00536335968	0.014083416181000001	0.010364329327999999	0.004609130971	0.0019180281099999998	0.015830196802	0.0151485
T	C	T	T	0.013761704021	0.228674918306	0.010304416928	0.0077	0.011787461775	0.0047	0.0844	0.012209070497000001	0.0096	0.0392	0.0954	0.009	0.028140661233000002	0.0229	0.0076	0.0193	0.01982741755	0.005398013994	0.0267	0.009540087238	0.0064	0.0011822265020000001	0.024328785234	0.00553249918	0.012418585885000001	0.00724914536	0.011880932482000001	0.006193158626	0.0134621373	0.045544
A	T	A	A	0.004021520333	1.32377e-07	0.008428563566	0.0048	0.008902904323	0.0006	0.001	0.013365082811	0.0121	0.0	0.0002	0.0058	0.001243618346	0.0	0.0021	0.0081	0.00061300245	0.0030372108039999996	0.0011	0.000574401358	0.0083	0.049619229711999994	0.0	0.001166747126	0.020430527125	0.004459339879	0.143076389009	0.000964030891	0.0	0.0075743
A	T	C	A	0.002371144163	0.000113069562	0.00737309667	0.0039	0.0073992024959999994	0.0033	0.0008	0.012431202076999999	0.0042	0.0002	0.0001	0.0065	0.001060001878	0.0008	0.009	0.0073	0.0018785874720000002	0.0008111672139999999	0.0053	0.001971462059	0.0292	0.011666740464000002	0.0	1.5173057e-05	0.008892560661	0.012822242916	0.0014640853870000001	0.003365667809	0.003049595749	0.003738
A	T	G	A	0.002810909959	0.000532929416	0.00735730002	0.01	0.011508051457	0.0	0.0009	0.014036657067	0.0068	0.0	0.0007	0.0046	0.00010255435999999999	0.0	0.0009	0.008	0.0010873496850000001	0.004503207138	0.0045	0.000190586616	0.0027	0.06791545421299999	0.000237418521	0.006332455573	0.00624194848	0.001172344272	0.001226280897	0.00178575365	0.003909981984	0.0065906
A	T	T	A	0.008360909345	0.000149110959	0.008753938991	0.003	0.011193623195	0.0053	0.0035	0.024109916595999998	0.0185	0.0012	0.0003	0.006	0.000971812099	0.0009	0.0079	0.0084	0.002045493651	0.002736523185	0.0033	0.007421103528	0.0043	0.01459991758	0.0	4.967216e-06	0.014850877622	0.003993137549	0.002535197951	0.0056530891000000005	0.005105527437	0.0093447
C	T	A	A	0.001182587416	0.000154598981	0.007571320259999999	0.0075	0.005043163511	0.0001	0.0	0.012024217521999999	0.0055	0.0	0.0004	0.0017	0.000285158991	0.0	0.0016	0.0054	3.0079241e-05	0.000412346353	0.0043	4.5042363999999996e-05	0.0	0.086898545516	0.000594528453	0.0027666348379999997	0.026296323089	0.0035614226809999997	0.330601017471	0.002566579967	0.0017654475030000002	0.0053118
C	T	C	A	0.001903166857	0.00046401902800000003	0.012725463528	0.0111	0.006208843676	0.0026	0.0014	0.017881092423	0.0049	0.0001	0.0011	0.0086	0.000222287328	0.0034	0.0043	0.0128	0.010223747696	0.00249141131	0.0053	0.004389055645	0.0037	0.053706846809	0.0	0.0026944624540000003	0.015799883085	0.0039016109810000002	0.002813598808	0.019610897429	0.00038335911699999997	0.0067873
C	T	G	A	0.0014879606299999998	0.000230409809	0.011508561865000001	0.0342	0.01050756897	0.0008	0.0007	0.016356774533	0.0051	0.0003	0.0006	0.0031	0.00028695182799999997	0.0002	0.0027	0.013	0.004467036232	0.005523045712999999	0.0021	0.0011278358419999999	0.0025	0.213220866558	0.0001731204	0.006911164721	0.062860606381	0.00239030418	0.004396857083	0.008833600032	0.003556845215	0.0082628
C	T	T	A	0.002179344412	0.0005748855870000001	0.016456177696	0.0115	0.009784640746	0.0011	0.0018	0.026247801916999998	0.0069	0.0009	0.0004	0.0054	8.00446e-07	0.002	0.0007	0.0096	0.031244883388	0.003313713273	0.0022	0.0023855413209999997	0.001	0.061827507476	0.000457813099	0.0029152001650000004	0.036622351112000004	0.001635922667	0.005430891633	0.010942609820000001	0.002232755492	0.0
G	T	A	A	0.000689289439	0.00011499421	0.004434782559	0.0069	0.006740387717000001	0.0	0.0	0.008139178608	0.003	0.0	0.0003	0.0015	0.000137960405	0.0	0.0	0.003	8.545689e-06	0.001875434081	0.0026	0.000163129836	0.0	0.053709145693	0.0	0.002225127336	0.036217800837	0.002242886513	0.10985187198	0.000551460783	0.002930098053	0.003738
G	T	C	A	0.000552409528	0.00029386205999999996	0.005615432411	0.0052	0.0040215964799999995	0.0028	0.0	0.007910080318	0.0029	0.0001	0.0003	0.0039	0.000252867405	0.0025	0.0038	0.004	0.002573466959	0.001510309757	0.0	0.0037991795030000003	0.0142	0.009489396694	0.000183203812	0.004853149157	0.005847109647	0.005207287095	2.3455678e-05	0.003163987597	0.0	0.0033445
G	T	G	A	0.0012002288469999999	8.872134400000001e-05	0.008070136472	0.0133	0.006814352288000001	0.0006	0.0006	0.009057263056	0.0028	0.0	0.0004	0.0019	0.00015351746100000002	0.0	0.0026	0.0051	0.003538822593	0.0015053687760000001	0.0016	0.0008283336999999999	0.0031	0.050293902428	0.0	0.000195758628	0.038241179315	0.001358121778	0.0015659371590000001	0.0021528470129999998	0.000533632401	0.0050167
G	T	T	A	0.002107136837	0.00021575546600000002	0.008679121744	0.0045	0.005101032909	0.0021	0.001	0.017812238647	0.0036	0.0004	0.0001	0.0031	0.000122745552	0.0009	0.0043	0.0033	0.0038790099609999997	0.0036110252020000004	0.0052	0.001900746587	0.0041	0.010601457233	0.0	0.0	0.020167954419	0.002513112942	0.0	0.002007733244	0.0	0.0063939
T	T	A	A	0.0056001554229999995	8.0752486e-05	0.007132681354	0.0045	0.009205637343	0.0002	0.001	0.015139996236	0.0215	0.0	0.0003	0.0057	0.000403261316	0.0	0.0008	0.0085	0.000698812311	0.004663278043	0.0039	0.000924547968	0.0027	0.040810502825000004	0.0	0.0	0.021830329049	0.000628145256	0.052813887494	0.00020323756300000002	0.0011912074340000001	0.0076726
T	T	C	A	0.0019990792600000002	4.802898e-06	0.009102797826999999	0.0046	0.006835344247	0.0008	0.0015	0.012093554606000001	0.0027	0.0008	0.0	0.0132	0.000771813274	0.0016	0.0019	0.0087	0.002579358604	0.002578155543	0.0048	0.000708206814	0.0045	0.025570395800999998	0.0	0.007994129155	0.003405686728	0.005073753861	4.7091785e-05	0.010180964867999999	0.001682664015	0.0064922
T	T	G	A	0.001090065693	6.6605043e-05	0.006565863040999999	0.0082	0.007144208769	0.0	0.001	0.00836254659	0.014	0.0	0.0	0.0037	0.000245194218	0.0	0.0006	0.0063	2.1133638999999997e-05	0.002016738361	0.0052	9.7003127e-05	0.0	0.06984521808500001	0.000231525618	0.011202143591	0.010191520401	2.0138391e-05	0.0	0.0032504272269999997	0.0024387560000000003	0.0036396
T	T	T	A	0.003981022761	0.00027631589100000003	0.014712135403	0.0045	0.010240850413	0.0007	0.005	0.027653296254	0.0139	0.0028	0.0008	0.0094	0.000160345975	0.0012	0.0003	0.008	0.003883130589	0.002818679447	0.0085	0.00231348906	0.0008	0.023579061797000003	0.0	0.00027057876799999996	0.014527539313	0.0012355384699999999	0.001929770813	0.016492812256	0.0	0.0
A	T	A	C	0.01391577303	0.001303509558	0.013035709432000001	0.0084	0.035366735114	0.0075	0.0005	0.016206510101	0.0252	0.0031	0.0006	0.0466	0.000549454166	0.0026	0.0115	0.0717	0.0026973140250000005	0.002933053644	0.0145	0.016395062964	0.0265	0.016839930949	0.00106844882	0.004726009142	0.020663282773	0.055028652133	0.005047301081	0.004092746888	0.010119181163	0.0
A	T	C	C	0.006274960600000001	0.000425576677	0.00918628969	0.002	0.013771102128999999	0.0056	0.0001	0.00778780282	0.0105	0.0052	0.0015	0.0317	0.00014550666100000001	0.0046	0.0073	0.0171	0.008078150072	0.0015132847630000001	0.0048	0.019251793639	0.0165	0.001108262382	0.00022157315900000002	0.000627949341	0.009502478424	0.027594604208	0.0018456912280000002	0.007880729211	0.006349682655	0.0087547
A	T	G	C	0.010137636154	0.000575473007	0.011716920076999999	0.0081	0.028449051657	0.0217	0.0007	0.009852583553	0.0176	0.0026	0.0008	0.0487	0.000279178024	0.0035	0.0073	0.0348	0.004432870698	0.0033296689549999997	0.0135	0.054784918009000004	0.0224	0.004913616405	0.000498801514	0.002723758627	0.019911492456	0.051791044050000005	0.0056888138789999996	0.005520833604	0.014659610308	0.0090498
A	T	T	C	0.009256316389	0.001488164093	0.016978870798	0.0036	0.027302974158	0.0023	0.0011	0.021829463826	0.0247	0.004	0.0003	0.025	0.000267461432	0.0025	0.0063	0.0497	0.003140370209	0.005491317771	0.016	0.007341269916	0.0189	0.002630523933	0.000313240541	0.0071223684699999994	0.014488390255	0.039072244419	0.002592754577	0.0032324840000000003	0.007892413403	0.0
C	T	A	C	0.004176674882	0.000546619204	0.007895012611	0.0052	0.014238629786	0.0062	0.001	0.005173842417	0.0154	0.0005	0.0001	0.0312	4.2751466e-05	0.0006	0.0032	0.0146	0.007426999645999999	0.00019216932	0.0066	0.014867696528000001	0.0219	0.004027346334	0.0	0.0018488765349999998	0.009028014894	0.037889377691	0.004899079238	0.020738003352	0.0	0.0
C	T	C	C	0.005252593331000001	0.000392332573	0.014431170362	0.0026	0.01248950044	0.004	0.0008	0.010936893768	0.0118	0.0019	0.0004	0.0385	4.3307542e-05	0.0053	0.005	0.0194	0.039657001207	0.0030501925809999996	0.007	0.018356161025	0.01	0.001352443929	0.0	0.004453689857	0.010771632420000002	0.021740734953	0.005724448467	0.043283797246000004	0.002774953681	0.0
C	T	G	C	0.007013225309999999	0.000362024508	0.008422972144	0.01	0.018741631229	0.027	0.001	0.005657773602	0.0154	0.0015	0.0001	0.0415	5.4272534e-05	0.0016	0.0128	0.019	0.028609696263	0.0025964641930000002	0.004	0.074150562563	0.0211	0.002749666137	0.000320704886	0.0	0.013350661310000001	0.047240103343	0.005661478992	0.037088261728	0.006902414708999999	0.0
C	T	T	C	0.006713813119	0.0005609001260000001	0.011932430465	0.0054	0.019054082944	0.0033	0.0045	0.011120389322	0.0275	0.002	0.0009	0.0324	7.639440000000001e-07	0.0027	0.0035	0.0263	0.101869657701	0.001310028744	0.0053	0.011001118252999998	0.0204	0.002363353537	0.0	0.001597389007	0.008961029966	0.020740621431	0.003900589062	0.005052716018	0.0030414248950000004	0.0
G	T	A	C	0.011247835116	4.673852e-06	0.006850055574	0.0061	0.016294982792	0.0122	0.0002	0.005720778549	0.0091	0.0064	0.001	0.0573	0.0010540812219999999	0.0078	0.0195	0.0161	1.1401335e-05	0.0005291264680000001	0.0039	0.002469317074	0.1426	0.004217454113	0.000251168628	0.00126974984	0.017489823879	0.098052824719	0.004777380354	0.003655048127	0.007090803763	0.0
G	T	C	C	0.006999724257	0.000186065927	0.006260749013999999	0.0016	0.009574560592999999	0.0059	0.0001	0.005181051502	0.0097	0.0101	0.0016	0.0274	0.000529899747	0.0127	0.0499	0.0099	0.009657713318	0.002279130829	0.003	0.001565632906	0.0665	0.0	0.0005382184889999999	0.0067103399959999996	0.004045612446	0.040226363963	0.00196495433	0.007071175327	0.007111327534	0.0065906
G	T	G	C	0.004977592617	4.95044e-07	0.006098762993	0.0042	0.014103929348	0.0115	0.0003	0.005040707471	0.0094	0.0054	0.0019	0.041	0.000630095718	0.0082	0.0154	0.0148	0.004654129131	0.005871056581	0.006	0.027341755021000003	0.0884	0.001474884534	0.0	0.000277684976	0.013402246274000001	0.044620700983	0.001229167749	0.008232238440000001	0.005643063554	0.0078694
G	T	T	C	0.010667406133	0.0005785981040000001	0.0075093438589999995	0.0024	0.015666874692	0.0042	0.0081	0.008488220258	0.0126	0.0124	0.0023	0.0405	0.000676187888	0.0086	0.0094	0.0142	0.008149234601	0.004771565739	0.0099	0.0014982647959999999	0.1003	0.001561042738	0.000995769681	0.0042384776689999995	0.014159693736	0.055528068279999995	0.0037472250130000002	0.00040788451000000004	0.011237674345	0.0084596
T	T	A	C	0.008073616351	0.00010193235199999999	0.009115495077	0.0028	0.017059640976	0.0059	0.0023	0.004901072379	0.0156	0.003	0.0002	0.05	0.000784056118	0.0018	0.0068	0.0246	0.001708586711	0.00030230356500000004	0.0052	0.005734229562	0.0389	0.00480366974	0.0	0.001682291048	0.01451505009	0.028789680542000002	0.001721015277	0.009929552068000001	0.011498665964	0.0
T	T	C	C	0.004857381178	0.000470343659	0.010953790932	0.0016	0.014195709147000002	0.0035	0.0018	0.006081011299000001	0.0137	0.0097	0.0009	0.0342	0.00013297488799999998	0.0056	0.0099	0.0183	0.011074152072	0.006260791115	0.002	0.011234254668	0.0313	0.0009121575119999999	0.000230608944	0.0023445276560000003	0.007406083456999999	0.036639492442	0.003489212553	0.029010563206	0.0035842150380000003	0.0091481
T	T	G	C	0.008325454207	0.00019235420300000002	0.006113033219	0.0036	0.012596501722	0.0106	0.0019	0.001712484699	0.0098	0.0065	0.0007	0.032	3.7402404000000004e-05	0.0034	0.0039	0.0165	0.0059320027630000004	0.001541265329	0.0057	0.023767611345000002	0.0249	0.0017817356799999999	0.00023951377499999998	0.000481274164	0.004892531217	0.01914369428	0.001152846581	0.015683218557	0.0016942966699999998	0.0060004
T	T	T	C	0.006257105605	0.000585330275	0.010774336259000001	0.0022	0.017375139145	0.0029	0.0024	0.01000344183	0.0309	0.0099	0.0005	0.0371	0.000179702846	0.0026	0.0047	0.0174	0.007208218396	0.001357797089	0.0038	0.005395186301	0.0274	0.0	0.0	0.00035814800199999997	0.017014780759000002	0.023071688831	0.001527957003	0.017291563618	0.003799705772	0.0
A	T	A	G	0.0015876364230000002	3.3718411e-05	0.002351368076	0.0	0.003462151975	0.0	0.0	0.004219719284	0.0335	0.0	0.0	0.0012	0.00038619979	0.0	0.0	0.0052	5.3139249e-05	0.000386138197	0.0014	1.765291e-06	0.0	0.001651998615	0.0	0.0	0.005281679682	8.0653426e-05	0.001136337392	0.006364675555	0.0	0.0053118
A	T	C	G	0.001784091288	2.4844825999999997e-05	0.001464231129	0.0002	0.002246592659	0.0017	0.0	0.000793671329	0.0051	0.004	0.0	0.001	0.00011238321400000001	0.002	0.0006	0.0042	0.006468661271000001	0.00125498208	0.0	0.000381387913	0.0031	0.0	0.0	0.0014639506880000002	0.0	0.00016317121	0.0009589763800000001	0.016610905647	0.0	0.0024592
A	T	G	G	0.001385830552	0.00027345407800000003	0.009053777641999999	0.0015	0.005490216837000001	0.0007	0.0009	0.006865800374	0.0052	0.0015	0.0001	0.0018	3.6000696e-05	0.0007	0.0012	0.0061	0.0034815490120000004	0.002369216073	0.001	0.0006587580869999999	0.0016	0.001086872758	0.0	0.0008476125299999999	0.0071364216440000005	0.001255079507	6.766061e-05	0.006592842245	0.0029251714480000002	0.0062955
A	T	T	G	0.0031585393119999998	0.000217694872	0.007030976419	0.0002	0.003821226712	0.0029	0.0	0.002939922259	0.0193	0.0137	0.0	0.003	0.000192493754	0.0056	0.0029	0.0076	0.030926375169	0.00033860288099999997	0.0017	0.000532125222	0.0018	0.0	0.0	0.001075455294	0.0	0.001850383492	0.00025602774799999997	0.086392897435	0.0	0.0095416
C	T	A	G	0.000302691186	0.00011378460300000001	0.001974181146	0.0	0.0020416489410000002	0.0001	0.0	0.002424050552	0.0216	0.0022	0.0	0.0013	1.5094208e-05	0.0	0.0	0.0002	9.1469787e-05	6.1002547999999995e-05	0.0	2.3264084e-05	0.0	0.001120356515	0.0	0.0	0.0	9.539626e-05	0.0	0.009589841941	0.001116854814	0.0046233
C	T	C	G	0.00209850244	2.2095087e-05	0.005824295544999999	0.0013	0.003478502118	0.004	0.0008	0.002096210616	0.0064	0.0018	0.0001	0.0049	0.00014762484	0.002	0.0019	0.0082	0.019814293551	0.0020156969130000002	0.0011	0.008476494525	0.0005	0.001064583571	0.000190144342	0.002185437348	0.002886454337	0.0039194551	0.00038124498399999996	0.033913223722	0.0	0.0060004
C	T	G	G	0.0015995485	0.000228245948	0.010464654525	0.0046	0.007147456226	0.005	0.0009	0.006604046293999999	0.0126	0.0037	0.0011	0.0045	4.598729999999999e-05	0.0005	0.0007	0.0067	0.013449837633	0.005311967254	0.0013	0.015383776115000001	0.0004	0.004188568126	0.0	0.000113909674	0.011769492498999999	0.005497357314	0.000403257236	0.018516481606	0.0021696933460000002	0.0073775
C	T	T	G	0.002758537619	6.711134e-05	0.008724387302	0.0012	0.011486811509	0.0086	0.0013	0.0048667138589999995	0.0509	0.0182	0.0009	0.0063	0.000463714722	0.0063	0.0045	0.0186	0.261456614079	0.0023416291779999997	0.0019	0.002185394659	0.0032	0.0016294095730000002	0.00021083498	0.002533718333	0.008550807482	0.006788718691	0.0014390960690000001	0.118967102954	0.001143663251	0.0091481
G	T	A	G	9.9045003e-05	9.5552392e-05	0.004144488018	0.0	0.001627664547	0.0	0.0	0.0009745786650000001	0.0072	0.0	0.0	0.0	1.8489857e-05	0.0	0.0	0.0	3.9193820999999995e-05	0.001341532464	0.0	3.579149e-06	0.0	0.0	0.0	0.0	0.005546226924	3.7393232e-05	0.0	0.0	0.0	0.0032461
G	T	C	G	0.00020236564600000003	4.7002381e-05	0.004501985313	0.0	0.000327734937	0.0016	0.0	0.000524821555	0.0006	0.002	0.0	0.0004	9.3373513e-05	0.0019	0.0022	0.0032	0.009078461515	9.204309999999999e-07	0.0	0.002830575073	0.0006	0.0	0.0	0.001073632302	0.0	0.002460704995	5.0790565e-05	0.0	0.0	0.001869
G	T	G	G	0.001188353185	0.000109925703	0.016391452608000002	0.0018	0.005948879802	0.001	0.0017	0.006087753467	0.005	0.0009	0.001	0.0011	1.0579194e-05	0.0012	0.0037	0.0008	0.004782775461	0.009694999981	0.0043	0.0027332194050000004	0.0004	0.0018775891810000002	0.00018713241399999998	0.002924696996	0.008685244444	0.0008172015630000001	0.00474291855	0.004217808299	0.003640593813	0.0033445
G	T	T	G	0.000800723342	8.647718e-05	0.007067236643	0.0002	0.003307466591	0.0035	0.0009	0.005427433785	0.0185	0.003	0.0	0.0032	5.3741207000000006e-05	0.0038	0.019	0.0044	0.063497756582	0.0028905535190000002	0.0025	0.0035585585649999998	0.0008	0.0	0.0	0.000825098263	0.0027685716830000004	0.007833561271000001	0.00229847603	0.031648997321	0.006181023776	0.0056069
T	T	A	G	0.001397553749	7.173694999999999e-05	0.005427184240999999	0.0	0.00520287442	0.0009	0.0	0.0017432213620000002	0.0502	0.005	0.0	0.0019	0.000546581847	0.0	0.0	0.0068	0.000133410642	3.6318404e-05	0.0032	2.69147e-07	0.0	0.0016516987609999998	0.0	0.0	0.002081479927	8.534935000000001e-06	0.001189022454	0.009389658706	0.0	0.0086563
T	T	C	G	0.001291736985	1.4281456e-05	0.0061602504229999995	0.0003	0.005131607914	0.0019	0.001	0.002549838329	0.0081	0.0092	0.0	0.0027	0.000235347085	0.0015	0.0004	0.0069	0.009613345245	0.00323383799	0.0018	0.00037723443700000004	0.0018	0.0	0.0	0.0	0.000578978775	0.002718509845	0.000280295354	0.030117076984000003	0.0	0.0043282
T	T	G	G	0.00203107688	0.000206615168	0.011076526260999999	0.003	0.0060552541	0.0011	0.001	0.006030395185	0.0088	0.0022	0.0003	0.0011	4.79022e-07	0.0002	0.0009	0.0049	0.004522462318	0.000754601773	0.0011	0.000515421599	0.0003	0.002572751958	0.00024750193299999997	0.0013605048499999999	0.009429195885	0.0013691611730000002	0.002353055589	0.012698750811000001	0.000353695951	0.0082628
T	T	T	G	0.00403012816	2.3598204e-05	0.013000984209	0.0011	0.013369935833999999	0.0072	0.0014	0.007223998893	0.0545	0.0633	0.0003	0.0032	0.000670588327	0.0025	0.0033	0.0163	0.058040407759999996	0.002126441532	0.0013	0.000615656691	0.0003	0.0	0.0	6.9515778e-05	0.007869671577	0.002568076726	0.00013956128500000001	0.23365978327599998	0.006104834135999999	0.0
