chromosome	start	end	strand	ddb_g	genename	description
chr1	1890	3287	+	DDB_G0267178	DDB_G0267178_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	3848	4855	+	DDB_G0267180	DDB_G0267180_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	5505	7769	+	DDB_G0267182	DDB_G0267182_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	8308	9522	-	DDB_G0267184	DDB_G0267184_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	9635	9889	-	DDB_G0267186	DDB_G0267186_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	10033	12183	+	DDB_G0267188	DDB_G0267188_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	12436	13044	-	DDB_G0267190	DDB_G0267190_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	17379	17833	+	DDB_G0267194	DDB_G0267194	NA
chr1	17928	18299	+	DDB_G0267196	DDB_G0267196	NA
chr1	18497	18694	+	DDB_G0267198	DDB_G0267198	NA
chr1	20869	21249	+	DDB_G0267202	DDB_G0267202_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chr1	21490	23468	+	DDB_G0267204	DDB_G0267204_ps	putative pseudogene%3B similar to a family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0267252%22%3EDDB_G0267252%3C%2Fa%3E
chr1	23929	26416	+	DDB_G0267206	DDB_G0267206_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	28333	28920	+	DDB_G0267208	DDB_G0267208_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	29137	32238	+	DDB_G0267210	DDB_G0267210_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	36170	36667	-	DDB_G0267216	DDB_G0267216	NA
chr1	36858	37064	-	DDB_G0267218	DDB_G0267218	NA
chr1	37303	37533	-	DDB_G0267220	DDB_G0267220	NA
chr1	38063	38542	-	DDB_G0267222	DDB_G0267222	NA
chr1	38714	39010	-	DDB_G0267224	DDB_G0267224	NA
chr1	39234	39494	-	DDB_G0267226	DDB_G0267226	NA
chr1	39890	42049	+	DDB_G0267228	DDB_G0267228_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chr1	42193	43179	+	DDB_G0267230	DDB_G0267230	NA
chr1	46105	48369	-	DDB_G0267236	DDB_G0267236_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	49019	50026	-	DDB_G0267238	DDB_G0267238_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	52425	54982	-	DDB_G0267240	DDB_G0267240_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	55333	56177	-	DDB_G0267242	DDB_G0267242_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	56374	56811	-	DDB_G0267264	DDB_G0267264_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	57242	59413	-	DDB_G0267244	DDB_G0267244_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	60063	61070	-	DDB_G0267246	DDB_G0267246_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	61559	62221	-	DDB_G0267248	DDB_G0267248_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	63591	66041	+	DDB_G0267250	DDB_G0267250_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chr1	66189	67191	+	DDB_G0267252	DDB_G0267252	NA
chr1	68992	72709	+	DDB_G0267254	DDB_G0267254_ps	putative pseudogene
chr1	74542	76806	-	DDB_G0267258	DDB_G0267258_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	77456	78463	-	DDB_G0267260	DDB_G0267260_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	79066	79773	-	DDB_G0267262	DDB_G0267262_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	88569	88844	-	DDB_G0267270	DDB_G0267270_RTE	small ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	89316	90391	+	DDB_G0267272	DDB_G0267272_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	90719	92580	+	DDB_G0267274	DDB_G0267274_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	94094	94636	-	DDB_G0267278	DDB_G0267278_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	94704	96086	-	DDB_G0267280	DDB_G0267280_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	97144	98073	-	DDB_G0267282	DDB_G0267282_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	100754	101026	-	DDB_G0267286	DDB_G0267286	NA
chr1	104223	105230	+	DDB_G0267292	DDB_G0267292_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	105880	108144	+	DDB_G0267294	DDB_G0267294_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	108593	109261	-	DDB_G0267296	DDB_G0267296_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	109429	109997	-	DDB_G0267298	DDB_G0267298_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	110783	112804	+	DDB_G0267300	DDB_G0267300_RTE	ORF1%2FORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	113142	113324	-	DDB_G0267302	DDB_G0267302_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	114394	116973	+	DDB_G0267304	DDB_G0267304_RTE	ORF3 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	117148	121209	-	DDB_G0267306	DDB_G0267306_RTE	long terminal repeat retrotransposon Skipper GAG-PRO-POL%3B refer to GenBank AF049230 for full length consensus element
chr1	121433	121843	-	DDB_G0267308	DDB_G0267308_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr1	121880	122398	-	DDB_G0267310	DDB_G0267310_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr1	123714	124664	-	DDB_G0267314	DDB_G0267314_RTE	fused fragments of the DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	127571	128086	-	DDB_G0267322	DDB_G0267322_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	128570	129577	+	DDB_G0267324	DDB_G0267324_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	129934	132491	+	DDB_G0267326	DDB_G0267326_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	132940	134658	-	DDB_G0267328	DDB_G0267328_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	135308	136312	-	DDB_G0267330	DDB_G0267330_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	137038	137749	-	DDB_G0267332	DDB_G0267332	NA
chr1	138334	138819	-	DDB_G0267338	DDB_G0267338_RTE	ORF3 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	139298	139765	+	DDB_G0267334	DDB_G0267334_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	142027	144884	-	DDB_G0267336	DDB_G0267336_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chr1	145444	148322	+	DDB_G0267342	DDB_G0267342_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	149314	151160	+	DDB_G0267344	DDB_G0267344	NA
chr1	151286	152888	+	DDB_G0267346	DDB_G0267346	NA
chr1	153529	154134	-	DDB_G0267348	DDB_G0267348_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	154265	154810	-	DDB_G0267350	DDB_G0267350_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	158583	161024	+	DDB_G0267352	DDB_G0267352_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	161143	162112	+	DDB_G0267354	DDB_G0267354_TE	ORF2 (contains 2 introns) encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	162941	166942	-	DDB_G0267356	DDB_G0267356_RTE	long terminal repeat retrotransposon Skipper GAG-PRO-POL%3B refer to GenBank AF049230 for full length consensus element
chr1	167225	168373	-	DDB_G0267358	DDB_G0267358_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr1	169365	173608	-	DDB_G0267362	DDB_G0267362_RTE	long terminal repeat retrotransposon Skipper GAG-PRO-POL%3B refer to GenBank AF049230 for full length consensus element
chr1	173832	174272	-	DDB_G0267364	DDB_G0267364_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr1	174742	175393	-	DDB_G0305708	DDB_G0305708_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	184608	186454	+	DDB_G0305706	DDB_G0305706_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr1	186996	190370	-	DDB_G0267366	DDB_G0267366_RTE	long terminal repeat retrotransposon Skipper GAG-PRO-POL%3B refer to GenBank AF049230 for full length consensus element
chr1	191815	192624	-	DDB_G0267370	DDB_G0267370_TE	ORF2 (contains 2 introns) encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	193516	194159	+	DDB_G0267372	DDB_G0267372_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	194176	194850	+	DDB_G0268474	DDB_G0268474_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	195959	196984	-	DDB_G0268476	DDB_G0268476_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	198724	200556	-	DDB_G0268260	DDB_G0268260	NA
chr1	201217	203254	+	DDB_G0267458	DDB_G0267458	NA
chr1	203419	206582	-	DDB_G0267480	nup93	similar to the mammalian nucleoporin complex component Nup93 to and to S. cerevisiae NIC96 that are required for correct nuclear pore assembly
chr1	206837	207171	+	DDB_G0267482	DDB_G0267482	NA
chr1	208100	208842	+	DDB_G0267484	acp1	conserved low molecular weight phosphotyrosine protein phosphatase%2C acts on tyrosine phosphorylated proteins%2C low-MW aryl phosphates and natural and synthetic acyl phosphates
chr1	208945	209681	-	DDB_G0267486	DDB_G0267486	contains a 2Fe-2S ferredoxin-type iron-sulfur binding domain
chr1	210356	212554	+	DDB_G0267488	DDB_G0267488	NA
chr1	212712	214898	-	DDB_G0267490	ChLim	contains a N-terminal Calponin Homology (CH) domain%2C 3 LIM domains%2C and 4 LIM-related domains (LRDs)
chr1	215251	217562	-	DDB_G0267492	DDB_G0267492	putative metalloprotease of the peptidase M41 family%2C which belong to a larger family of zinc metalloproteases%3B includes the cell division protein FtsH
chr1	217763	218365	+	DDB_G0267494	DDB_G0267494	NA
chr1	218913	225973	+	DDB_G0267496	DDB_G0267496	NA
chr1	226283	227085	+	DDB_G0267498	pgpep	pyrrolidone-carboxylate peptidase selectively removes pyroglutamate from the amino terminus of proteins and peptides
chr1	227165	228343	-	DDB_G0267500	DDB_G0267500	NA
chr1	229145	230944	-	DDB_G0267450	pakC	STE20%2FPAK protein kinase required for normal chemotaxis%3B contains PAK-box%2FP21-Rho-binding (CRIB) domain and pleckstrin homology (PH) domain
chr1	231364	232044	-	DDB_G0268264	DDB_G0268264	similar to Entamoeba histolytica 20 kDa antigen
chr1	233800	236723	+	DDB_G0268266	DDB_G0268266	similar to D. purpureum protein
chr1	236992	238491	-	DDB_G0267502	DDB_G0267502	NA
chr1	238722	242663	+	DDB_G0268614	msh6	NA
chr1	243053	245068	+	DDB_G0267468	adprt4	catalyzes ADP-ribosylation%2C a posttranslational protein modification in which the ADP-ribose moiety of NAD is transferred onto specific amino acid side chains of cell surface%2C secreted%2C cytosolic or nuclear proteins
chr1	245416	247229	-	DDB_G0267504	DDB_G0267504	NA
chr1	248894	251043	+	DDB_G0267506	aslH	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA
chr1	251537	252874	-	DDB_G0268268	DDB_G0268268	NA
chr1	254497	255225	-	DDB_G0267508	DDB_G0267508	NA
chr1	255654	256271	+	DDB_G0268478	DDB_G0268478	NA
chr1	256535	257366	-	DDB_G0267510	DDB_G0267510	similar to coiled-coil domain containing protein 43 (CCDC43)%3B contains two predicted coiled-coil domains
chr1	257711	258721	-	DDB_G0267512	DDB_G0267512	NA
chr1	259066	261816	-	DDB_G0267514	DDB_G0267514	member of the TKL (tyrosine kinase-like) group of protein kinases
chr1	263217	267660	-	DDB_G0267516	dhx57	putative RNA helicase%3B contains an RWD domain (RING finger and WD repeat)
chr1	269690	270976	-	DDB_G0267522	DDB_G0267522	NA
chr1	271374	272197	-	DDB_G0267524	ssr3	subunit of the TRAP complex aids in the translocation of nascent polypeptides into the lumen of the endoplasmic reticulum
chr1	272779	273967	+	DDB_G0267526	DDB_G0267526	NA
chr1	274124	275255	-	DDB_G0267528	DDB_G0267528	NA
chr1	276695	277327	+	DDB_G0267530	DDB_G0267530	NA
chr1	277655	278789	-	DDB_G0267408	psmA3	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr1	279600	281837	-	DDB_G0268270	DDB_G0268270	contains a predicted signal peptide and a putative C-terminal transmembrane domain
chr1	283495	286152	+	DDB_G0267532	DDB_G0267532	NA
chr1	286362	287906	-	DDB_G0267388	dafE	NA
chr1	288484	289302	-	DDB_G0267534	DDB_G0267534	NA
chr1	289882	291134	+	DDB_G0267536	hibch	catalyzes the reaction: 3-hydroxy-2-methylpropanoyl-CoA %2B H2O %3D CoA %2B 3-hydroxy-2-methylpropanoate%3B ortholog of the mammalian HIBCH enzyme 
chr1	291771	293820	+	DDB_G0267538	DDB_G0267538	NA
chr1	294048	295439	-	DDB_G0268480	cdk10	putative cell division cycle 2 (CDC2)-like protein kinase%3B has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases
chr1	298527	300350	+	DDB_G0267470	dicB	forms a discoidin-inducing complex (DIC) with dicA1%2C pdsA%2C and an unknown protein%3B dicB alone does not induce discoidin expression
chr1	300608	303232	-	DDB_G0267540	scy1	N-terminal kinase-like (NTKL) protein%3B does not contain the consensus sequences required for kinase function%2C however%2C the SCY1 family encodes highly conserved non-canonical kinases that are believed to function
chr1	303809	304036	+	DDB_G0267542	DDB_G0267542	NA
chr1	304919	306988	-	DDB_G0268272	aslN	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA
chr1	307708	309784	-	DDB_G0267544	aslM	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA
chr1	311255	312670	+	DDB_G0267546	DDB_G0267546	NA
chr1	313115	316757	-	DDB_G0267548	elmoF	NA
chr1	318212	320010	+	DDB_G0268482	DDB_G0268482_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0274851%22%3EDDB_G0274851%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0269606%22%3EDDB_G0269606 %3C%2Fa%3E
chr1	320689	321165	+	DDB_G0268274	DDB_G0268274	NA
chr1	322112	322810	+	DDB_G0268278	DDB_G0268278	NA
chr1	323194	324597	+	DDB_G0267550	DDB_G0267550	NA
chr1	324845	325596	-	DDB_G0267552	DDB_G0267552	NA
chr1	325873	326929	+	DDB_G0267554	DDB_G0267554	NA
chr1	327145	330624	-	DDB_G0267556	DDB_G0267556	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr1	331477	336050	+	DDB_G0268280	DDB_G0268280	NA
chr1	336383	337455	+	DDB_G0267560	uprt	catalyzes the reaction UMP %2B diphosphate %3C%3D%3E uracil %2B 5-phospho-alpha-D-ribose 1-diphosphate
chr1	338107	338878	+	DDB_G0267420	sodA	superoxide dismutase of the SOD1 family%3B expressed at constant levels throughout the life cycle and upregulated upon oxidative stress%3B enriched in prespore cells
chr1	339546	341341	+	DDB_G0267562	stcA	NA
chr1	341837	343496	+	DDB_G0267564	DDB_G0267564	similar to D. purpureum protein%3B contains a predicted signal anchor sequence
chr1	343868	346712	-	DDB_G0267566	DDB_G0267566	putative protein serine%2Fthreonine kinase%3B contains an ankyrin repeat domain%3B similar to vertebrate Nek kinases which are involved in regulation of mitosis
chr1	348371	351563	+	DDB_G0268284	tgrO4	NA
chr1	351991	354465	-	DDB_G0267396	kif2	belongs to the NCD%2FKar3 subfamily%2C predicted to play a role in mitosis 
chr1	355159	357213	-	DDB_G0267568	gacO	NA
chr1	358932	360995	-	DDB_G0267570	DDB_G0267570	NA
chr1	361555	362932	-	DDB_G0267572	DDB_G0267572	NA
chr1	363410	364574	+	DDB_G0268286	DDB_G0268286	NA
chr1	364761	365278	-	DDB_G0267460	cybA	homolog of the mammalian flavocytochrome B small subunit p22phox%2C essential for spore formation
chr1	365942	366747	+	DDB_G0267574	DDB_G0267574	NA
chr1	366936	367540	+	DDB_G0267576	DDB_G0267576	NA
chr1	368155	368942	+	DDB_G0267578	DDB_G0267578	NA
chr1	369407	370211	+	DDB_G0267580	DDB_G0267580	NA
chr1	371018	373018	+	DDB_G0267582	DDB_G0267582	NA
chr1	373253	374947	-	DDB_G0267584	adcE	NA
chr1	375348	376736	+	DDB_G0267586	DDB_G0267586	NA
chr1	376992	379294	-	DDB_G0267588	pikI	NA
chr1	381029	382632	-	DDB_G0267590	DDB_G0267590	NA
chr1	383616	385211	+	DDB_G0267592	DDB_G0267592	NA
chr1	385503	385941	+	DDB_G0267594	pfdn2	component of the prefoldin complex responsible for targeting proteins to cytosolic chaperonin CCT
chr1	386296	390186	-	DDB_G0268288	DDB_G0268288	NA
chr1	390446	395584	-	DDB_G0267596	DDB_G0267596	NA
chr1	395715	397024	-	DDB_G0267598	DDB_G0267598	might be involved in fatty acid metabolism
chr1	397569	397823	-	DDB_G0268290	DDB_G0268290	NA
chr1	398417	399505	-	DDB_G0267600	DDB_G0267600	similar to HIBCH%2C might have 3-hydroxyisobutyryl-Coenzyme A hydrolase activity
chr1	400350	405975	-	DDB_G0267602	DDB_G0267602	NA
chr1	406648	408225	-	DDB_G0267604	mserS	catalyzes the reaction ATP %2B L-serine %2B tRNASer %3D AMP %2B diphosphate %2B L-seryl-tRNASer
chr1	408722	409582	+	DDB_G0267606	fcf1	NA
chr1	409670	410341	-	DDB_G0267608	DDB_G0267608	NA
chr1	411512	412435	-	DDB_G0267610	DDB_G0267610	there is a paralog of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0287085%22%3EDDB_G0287085 %3C%2Fa%3E
chr1	413651	414280	+	DDB_G0267612	DDB_G0267612	NA
chr1	414980	416538	+	DDB_G0267380	argE	NA
chr1	416596	417778	-	DDB_G0268292	DDB_G0268292	NA
chr1	420108	421374	-	DDB_G0267614	DDB_G0267614	NA
chr1	424007	425518	+	DDB_G0267454	ancA	ortholog of human SLC25A4%2C which catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane%3B contains six predicted transmembrane domains %3Cbr%2F%3E%3Cbr%2F%3E%3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr1	426116	427466	-	DDB_G0268294	DDB_G0268294_ps	putative pseudogene%3B fragment%2C nearly identical to %3Ca href%3D%22%2Fgene%2FDDB_G0291065%22%3EDDB_G0291065%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290815%22%3EDDB_G0290815%3C%2Fa%3E  
chr1	427853	430458	+	DDB_G0267616	DDB_G0267616	NA
chr1	430688	431774	-	DDB_G0268484	DDB_G0268484_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0291065%22%3EDDB_G0291065%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290815%22%3EDDB_G0290815%3C%2Fa%3E
chr1	433828	435890	+	DDB_G0267618	DDB_G0267618_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0268494%22%3EDDB_G0268494%3C%2Fa%3E 
chr1	436026	437354	-	DDB_G0267620	DDB_G0267620	NA
chr1	438237	438607	-	DDB_G0267622	srp9	component of the signal recognition particle (SRP)%2C which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulum
chr1	439137	440790	+	DDB_G0267624	DDB_G0267624	NA
chr1	441679	442307	-	DDB_G0267628	rad54_ps	putative pseudogene%3B fragment similar to%2C %3Ca href%3D%22%2Fgene%2FDDB_G0282997%22%3Erad54%3C%2Fa%3E
chr1	443514	444929	+	DDB_G0267630	kil1	necessary for efficient intracellular killing of K. pneumoniae%3B overexpression of kil1%2C a sulfotransferase%2C restores the ability of %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0267444%22%3E%3Ci%3Ephg1a%3C%2Fi%3E%3C%2Fa%3E mutants to grow on K. pneumoniae
chr1	445092	446321	-	DDB_G0267632	DDB_G0267632	NA
chr1	447485	447880	-	DDB_G0268298	DDB_G0268298	NA
chr1	448541	448611	+	DDB_G0294671	tRNA-Lys-UUU-2	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	448892	451792	+	DDB_G0267634	DDB_G0267634	NA
chr1	451992	454102	-	DDB_G0267636	mybM	contains three Myb DNA-binding domains
chr1	464992	474506	+	DDB_G0267638	DDB_G0267638	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr1	475634	475923	+	DDB_G0268300	DDB_G0268300	NA
chr1	476398	479414	-	DDB_G0267640	gtaE	has 18 amino acids between the two CX2C motifs
chr1	481685	483244	-	DDB_G0267448	DDB_G0267448	similar to yeast ERG24 involved in ergosterol biosynthesis
chr1	484012	485684	+	DDB_G0267642	DDB_G0267642	NA
chr1	485945	486391	-	DDB_G0268302	rpl38	protein component of the large (60S) ribosomal subunit
chr1	487456	488497	-	DDB_G0267390	psmB6	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)%3B shift of Dictyostelium cells from the proliferative to differentiated state%3B highly expressed during the early stage of differentiation
chr1	488923	490112	-	DDB_G0267644	DDB_G0267644	NA
chr1	490625	491661	+	DDB_G0267646	sec20	putative ortholog of SNARE protein SEC20
chr1	491895	494666	+	DDB_G0267648	DDB_G0267648	NA
chr1	495110	498317	+	DDB_G0267650	ireA	ortholog of the yeast IRE1 serine%2Fthreonine kinase%2Fendoribonuclease%2C a transmembrane protein involved in the unfolded protein response%3B contains a ribonuclease 2-5A domain and 3 pyrrolo-quinoline quinone (PQQ) domains
chr1	498516	501561	-	DDB_G0268486	DDB_G0268486_ps	putative pseudogene%2C contains protein kinase domain
chr1	504172	506744	+	DDB_G0268488	tgrO_ps1	putative pseudogene%3B immunoglobulin E-set family gene
chr1	507666	510414	+	DDB_G0268490	tgrO1	NA
chr1	511341	514098	+	DDB_G0267654	tgrO2	NA
chr1	515177	518377	+	DDB_G0268304	tgrO3	NA
chr1	518710	520050	+	DDB_G0267656	l2hgdh	ortholog of the H. sapiens L2HGDH%2C which when defective causes L-2-hydroxyglutaric aciduria-a rare autosomal recessive disorder
chr1	520101	522397	-	DDB_G0268492	DDB_G0268492	NA
chr1	523164	526205	+	DDB_G0267658	DDB_G0267658	NA
chr1	526607	527617	-	DDB_G0267660	DDB_G0267660	NA
chr1	527773	528777	+	DDB_G0267662	DDB_G0267662	NA
chr1	529188	529696	-	DDB_G0349281	DDB_G0349281	NA
chr1	530163	530978	-	DDB_G0349279	DDB_G0349279	NA
chr1	533108	536707	+	DDB_G0267666	gefW	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form%3B similar to son of sevenless
chr1	537016	537560	+	DDB_G0267668	hspL	NA
chr1	537622	538492	-	DDB_G0267670	DDB_G0267670	NA
chr1	539176	541233	+	DDB_G0267672	DDB_G0267672	NA
chr1	542006	544264	+	DDB_G0268494	DDB_G0268494	NA
chr1	545194	548149	+	DDB_G0267674	glcS	CAZy family GT3%3B catalyzes the reaction UDP-glucose %2B (1%2C4-alpha-D-glucosyl)(n) %3C%3D%3E UDP %2B (1%2C4-alpha-D-glucosyl)(n%2B1)
chr1	548246	550335	-	DDB_G0267676	DDB_G0267676	NA
chr1	551012	554227	-	DDB_G0267384	culB	similar to mammalian cullin 1 and 2 (CUL1%2C CUL2)%3B involved in ubiquitin-mediated protein degradation%3B regulates prestalk cell differentiation in %3Ci%3EDictyostelium%3C%2Fi%3E
chr1	554652	556085	-	DDB_G0268496	DDB_G0268496	NA
chr1	556660	557274	+	DDB_G0267678	tgrO_ps2	putative pseudogene%3B small fragment%2C similar to genes of the tgrO family
chr1	557566	558286	+	DDB_G0267680	DDB_G0267680	NA
chr1	558538	559011	-	DDB_G0268306	rpb9	component of the RNA polymerase II complex%3B ortholog of S. cerevisiae RPB9
chr1	559492	561036	+	DDB_G0267682	ercc1	ortholog of H. sapiens ERCC1 and S. cerevisiae RAD10 nucleotide excision repair genes%3B defects in ERCC1  cause cerebro-oculo-facio-skeletal syndrome type 4 (COFS4)
chr1	561516	564086	+	DDB_G0267684	DDB_G0267684	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D
chr1	564277	571070	-	DDB_G0267686	DDB_G0267686	member of the TKL (tyrosine kinase-like) group%3B belongs to the ARK (ankyrin repeat-containing kinase) family%2C although it does not contain ankyrin repeats%3B contains an RGS (Regulator of G protein Signaling) domain
chr1	573341	576172	-	DDB_G0268498	DDB_G0268498	NA
chr1	577816	578337	+	DDB_G0268310	DDB_G0268310	NA
chr1	578409	580066	-	DDB_G0267688	cpnD	Ca(2%2B)-dependent phospholipid-binding protein%3B contains two C2 domains and a VWFA domain.
chr1	580421	580716	-	DDB_G0268312	DDB_G0268312	NA
chr1	581198	585318	+	DDB_G0267690	icpA	homolog of INCENP involved in various cellular processes%3B contains the IN-box domain known to bind Aurora B kinase%3B null mutant has defects in cytokinesis%2C chromosome segregation%2C and spindle organization
chr1	585586	589828	-	DDB_G0295847	DDB_G0295847	contains one transmembrane domain at the carboxyl terminal
chr1	590684	595168	-	DDB_G0268500	DDB_G0268500	NA
chr1	595744	598501	-	DDB_G0268502	DDB_G0268502	NA
chr1	600250	604291	+	DDB_G0267692	DDB_G0267692	has a predicted signal peptide and a C-terminal transmembrane domain
chr1	604725	608840	+	DDB_G0268314	DDB_G0268314	NA
chr1	609146	611416	+	DDB_G0267430	abcG20	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr1	611485	613188	-	DDB_G0267694	DDB_G0267694	NA
chr1	613392	617600	-	DDB_G0268316	DDB_G0268316	NA
chr1	622339	622954	-	DDB_G0267696	DDB_G0267696	NA
chr1	623530	624219	-	DDB_G0267698	DDB_G0267698	NA
chr1	624602	625684	-	DDB_G0267700	DDB_G0267700	NA
chr1	625985	626830	-	DDB_G0267702	DDB_G0267702	NA
chr1	627395	628219	+	DDB_G0268318	DDB_G0268318	NA
chr1	628403	636330	-	DDB_G0267472	roco7	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains Roc%2C COR%2C WD40%2C and protein kinase domains%3B related to LRR-containing kinases but does not contain an LRR domain
chr1	637945	640745	-	DDB_G0268320	DDB_G0268320	similar to S. cerevisiae BUD7 (bud site selection protein 7) which is required for the export of specialised cargo from the Golgi.%3B belongs to the CHAPS (Chs5p-Arf1p-binding proteins) family
chr1	642853	659065	+	DDB_G0268504	DDB_G0268504	contains two putative coiled-coil domains%3B conserved in Dictyostelium and Polysphondylium
chr1	659396	660693	-	DDB_G0268322	DDB_G0268322	NA
chr1	661668	662715	+	DDB_G0267704	mcfT	ortholog of the yeast ODC2 and mammalian SLCA2521%2C which transport C5-C7 oxodicarboxylates across the mitochondrial membrane%3B belongs to the mitochondrial substrate carrier family %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr1	663020	666459	-	DDB_G0268506	DDB_G0268506	NA
chr1	670002	670854	+	DDB_G0267706	DDB_G0267706	NA
chr1	670930	671606	-	DDB_G0267708	vps25	component of the ELL complex%2C an RNA polymerase II transcription factor%2C and of the ESCRT-II complex (endosomal sorting complex required for transport)
chr1	673242	674981	+	DDB_G0267710	DDB_G0267710	NA
chr1	675419	675964	+	DDB_G0267712	DDB_G0267712	NA
chr1	676187	677352	-	DDB_G0267714	sf3b4	subunit of the splicing factor SF3B required for spliceosome assembly
chr1	678047	679663	-	DDB_G0267716	DDB_G0267716	NA
chr1	679845	681131	-	DDB_G0268324	DDB_G0268324	NA
chr1	682072	682953	-	DDB_G0268326	DDB_G0268326	NA
chr1	683499	695010	-	DDB_G0268328	DDB_G0268328	NA
chr1	695658	697436	+	DDB_G0267718	DDB_G0267718	NA
chr1	698211	699346	+	DDB_G0267720	DDB_G0267720	NA
chr1	699431	700187	-	DDB_G0267722	DDB_G0267722	NA
chr1	700627	703356	+	DDB_G0267724	DDB_G0267724	NA
chr1	704053	705840	-	DDB_G0268330	sgmD	similar to acid sphingomyelinase%2C which hydrolyze the phosphodiester bond in sphingomyelin to form ceramide
chr1	708045	708883	+	DDB_G0268332	uduA1	almost identical to %3Ca href%3D%22%2Fgene%2FDDB_G0267726%22%3E%3Ci%3EuduA2%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0267728%22%3E%3Ci%3EuduA3%3C%2Fi%3E%3C%2Fa%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant%3B %3Ci%3EG. Bloomfield  21-DEC-2009%3C%2Fi%3E
chr1	711088	711951	+	DDB_G0267726	uduA2	almost identical to %3Ca href%3D%22%2Fgene%2FDDB_G0268332%22%3E%3Ci%3EuduA1%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0267728%22%3E%3Ci%3EuduA3%3C%2Fi%3E%3C%2Fa%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant%3B %3Ci%3EG. Bloomfield  21-DEC-2009%3C%2Fi%3E
chr1	713027	713821	+	DDB_G0267728	uduA3	almost identical to %3Ca href%3D%22%2Fgene%2FDDB_G0268332%22%3E%3Ci%3EuduA1%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0267726%22%3E%3Ci%3EuduA2%3C%2Fi%3E%3C%2Fa%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant%3B %3Ci%3EG. Bloomfield  21-DEC-2009%3C%2Fi%3E
chr1	714031	716367	-	DDB_G0268334	DDB_G0268334	NA
chr1	719427	722987	+	DDB_G0267730	dst2	putative protein serine%2Fthreonine kinase%3B the kinase domain is similar to mitogen-activated protein kinases and other STE20-like kinases%3B stress-responsive kinase
chr1	723287	729518	-	DDB_G0267732	DDB_G0267732	NA
chr1	730241	731113	+	DDB_G0267734	DDB_G0267734	contains a SAM (and some other nucleotide) binding motif%3B similar to bacterial and eukaryotic methyltransferases
chr1	731136	731927	-	DDB_G0268336	DDB_G0268336	NA
chr1	733269	733982	+	DDB_G0268338	DDB_G0268338	NA
chr1	734616	735299	-	DDB_G0267736	DDB_G0267736_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr1	735632	741152	+	DDB_G0268508	DDB_G0268508_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	735884	735955	+	DDB_G0294673	tRNA-Thr-AGU-3	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	741690	742766	+	DDB_G0268510	DDB_G0268510_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr1	743291	746469	+	DDB_G0268340	DDB_G0268340_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr1	746953	749568	-	DDB_G0267740	DDB_G0267740	NA
chr1	750033	750105	-	DDB_G0294827	tRNA-Asn-GUU-8	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr1	752355	756877	+	DDB_G0267432	abcG15	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr1	758875	763979	+	DDB_G0267438	abcA2	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr1	764516	767051	+	DDB_G0267742	DDB_G0267742	similar to the %3Ci%3EDictyostelium%3C%2Fi%3E hydrolase Apeh%2C the conserved acylamino-acid-releasing enzyme
chr1	767152	768575	-	DDB_G0267744	DDB_G0267744	NA
chr1	769229	772726	-	DDB_G0268512	wrn	E. coli ATP-dependent DNA helicase RecQ is involved in genome maintenance%3B this is the ortholog of the H. sapiens Werner syndrome protein%3B defects in WRN cause the premature onset of multiple age-related disorders
chr1	774330	775937	+	DDB_G0267746	DDB_G0267746	NA
chr1	776324	778499	-	DDB_G0267748	cdc45	ortholog of the conserved CDC45 or CDC45L protein%3B in %3Ci%3ES. cerevisia%3C%2Fi%3Ee and %3Ci%3ES. pombe%3C%2Fi%3E required for initiation of chromosomal DNA replication
chr1	778920	779964	+	DDB_G0268342	DDB_G0268342_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0280075%22%3EDDB_G0280075%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0267762%22%3EDDB_G0267762%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fgene%2FDDB_G0267694%22%3EDDB_G0267694%3C%2Fa%3E
chr1	780178	783237	+	DDB_G0267750	DDB_G0267750	NA
chr1	783552	786233	+	DDB_G0267752	DDB_G0267752	NA
chr1	786322	788000	-	DDB_G0267754	DDB_G0267754	NA
chr1	788307	788933	-	DDB_G0267756	DDB_G0267756	NA
chr1	789209	791845	-	DDB_G0267758	DDB_G0267758	small Dictyostelium gene family
chr1	792299	795646	+	DDB_G0267760	tbck	similar to TBCK in human%2C fly%2C and worm%3B TBC domain-containing proteins in yeast are GTPase activator proteins%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr1	795721	797355	-	DDB_G0267762	DDB_G0267762	NA
chr1	798097	799005	+	DDB_G0268344	DDB_G0268344	NA
chr1	799346	800788	-	DDB_G0267764	DDB_G0267764	NA
chr1	802089	806703	+	DDB_G0268516	tbcD	NA
chr1	806804	809101	-	DDB_G0267766	gfm2	involved in the translocation of the nascent peptide chain from the ribosomal A-site to the P-site
chr1	809267	810455	+	DDB_G0267768	DDB_G0267768	widely conserved protein%2C very similar to M. musculus Myg1 (melanocyte proliferating gene 1)
chr1	810583	811472	-	DDB_G0268518	DDB_G0268518	NA
chr1	811678	815598	-	DDB_G0268520	DDB_G0268520	NA
chr1	816236	816791	+	DDB_G0268522	psmG3	conserved chaperone protein%2C which promotes assembly of the 20S proteasome%3B may form a dimer with psmG4 and act in concert with psmG1%2FpsmG2
chr1	816934	817967	-	DDB_G0267446	cnbA	regulatory subunit of the Ca%3Csup%3E2%2B%3C%2Fsup%3E%2Fcalmodulin-dependent serine%2Fthreonine protein phosphatase%3B contains an EF-hand%2C calcium binding motif
chr1	818727	818808	+	DDB_G0294675	tRNA-Ser-UGA-1	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr1	818921	818992	+	DDB_G0294677	tRNA-Cys-GCA-1	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr1	820114	821706	+	DDB_G0267770	DDB_G0267770	NA
chr1	822333	822414	-	DDB_G0294825	tRNA-Ser-UGA-4	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr1	824718	825057	+	DDB_G0267772	DDB_G0267772	NA
chr1	825289	827478	-	DDB_G0267774	abkC	atypical protein serine%2Fthreonine kinase%2C contains ABC1 kinase (protein kinase-like) domain%3B yeast ABC1 essential for the electron transfer in the BC(1) complex%3B E.coli homolog required for ubiquinone biosynthesis
chr1	827764	832445	-	DDB_G0267776	DDB_G0267776	NA
chr1	833130	835460	-	DDB_G0267414	repD	ortholog of H. sapiens xeroderma pigmentosum group D (XPD)%2C M. musculus ERCC2 and S. cerevisiae RAD3
chr1	835755	835825	+	DDB_G0294679	tRNA-Pro-UGG-2	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr1	835920	836792	+	DDB_G0267778	DDB_G0267778_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	836942	840235	+	DDB_G0267780	DDB_G0267780_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	842918	848447	+	DDB_G0268524	DDB_G0268524_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	843216	843286	+	DDB_G0294681	tRNA-Pro-UGG-3	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr1	849532	851483	-	DDB_G0267784	DDB_G0267784	NA
chr1	852021	853903	-	DDB_G0267786	DDB_G0267786	weakly similar to niban protein%2C a marker for renal carcinogenesis%3Cbr%3E  %3Cb%3ECommunity annotation:%3C%2Fb%3E  DDB_G0267786 appears to be cell-cycle regulated%2C expressed in late G2 at the same time when virtually all S-phase and M-phase specific genes are active (see graph on wiki page). The gene is slightly overexpressed in the rblA disruptant (1%2C5-fold) but appears primarily regulated by at present unknown%2C Rb-independent mechanisms. No ortholog of DDB_G0267786 is recognizable in yeast. %3Ci%3EHarry MacWilliams%2C August 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0267786%22%3E There is more information on the wiki page%3C%2Fa%3E 
chr1	854978	855903	-	DDB_G0267788	DDB_G0267788	NA
chr1	857737	858188	+	DDB_G0267790	DDB_G0267790	NA
chr1	858290	859778	-	DDB_G0267792	DDB_G0267792	NA
chr1	860671	862593	-	DDB_G0267794	DDB_G0267794	similar to human PUS10 (putative tRNA pseudouridine synthase Pus10)
chr1	863148	865925	+	DDB_G0267796	DDB_G0267796	conserved protein%2C similar to yeast CWC22%2C an essential putative spliceosomal component
chr1	866636	867904	+	DDB_G0268346	DDB_G0268346	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr1	868196	872344	+	DDB_G0268348	DDB_G0268348	NA
chr1	872490	873185	-	DDB_G0267456	cbp2	NA
chr1	874156	876609	+	DDB_G0268526	DDB_G0268526	NA
chr1	877260	880427	+	DDB_G0267798	DDB_G0267798	NA
chr1	881664	884690	+	DDB_G0268350	DDB_G0268350	NA
chr1	885149	889039	+	DDB_G0268352	DDB_G0268352	conserved in Dictyostelium%3B contains an immunoglobulin like fold domain%3B contains a predicted signal sequence and C-terminal transmembrane domain
chr1	889672	891537	+	DDB_G0267800	DDB_G0267800	NA
chr1	891838	894228	-	DDB_G0268354	gxcGG	NA
chr1	897809	898549	-	DDB_G0267802	DDB_G0267802	NA
chr1	899153	902230	+	DDB_G0267804	DDB_G0267804	NA
chr1	902491	902750	-	DDB_G0267806	ampA_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0275695%22%3E%3Ci%3EampA%3C%2Fi%3E%3C%2Fa%3E
chr1	903471	905468	+	DDB_G0267808	DDB_G0267808	NA
chr1	905813	908316	-	DDB_G0267810	DDB_G0267810	NA
chr1	909280	910089	+	DDB_G0267812	DDB_G0267812	NA
chr1	910680	912284	+	DDB_G0267814	DDB_G0267814	NA
chr1	913536	914612	+	DDB_G0267816	DDB_G0267816	NA
chr1	914771	918553	-	DDB_G0267818	DDB_G0267818	NA
chr1	919584	920681	-	DDB_G0267820	DDB_G0267820	NA
chr1	920878	922078	+	DDB_G0267822	DDB_G0267822	NA
chr1	922136	923726	-	DDB_G0267824	DDB_G0267824	NA
chr1	924216	925787	-	DDB_G0267826	DDB_G0267826	NA
chr1	926752	929405	+	DDB_G0267828	DDB_G0267828	NA
chr1	929880	932237	-	DDB_G0267830	gemA	simlar to M. musculus mitochondrial Rho1 and S. cerevisiae GEM1%2C a conserved tail-anchored outer mitochondrial membrane GTPase%3B contains two GTP-binding domains%2C two EF hand domains%2C and a C-terminal transmembrane domain
chr1	932664	934661	-	DDB_G0267832	DDB_G0267832	NA
chr1	936052	938060	+	DDB_G0268358	DDB_G0268358	ortholog of the human SDCCAG10 (Serologically Defined Colon Cancer Antigen 10)%3B PPIase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr1	939089	940508	+	DDB_G0267834	DDB_G0267834	NA
chr1	940974	942790	+	DDB_G0267836	DDB_G0267836	NA
chr1	943374	944711	-	DDB_G0267382	corA	actin binding protein regulating actin nucleation%2C involved in cytokinesis and cell motility
chr1	945806	947605	+	DDB_G0268528	DDB_G0268528_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	946092	946173	+	DDB_G0294683	tRNA-Ser-UGA-2	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr1	948334	948612	-	DDB_G0268360	DDB_G0268360	conserved in D. purpureum
chr1	949001	949753	+	DDB_G0267838	DDB_G0267838	has an endoplasmic reticulum retention signal at the C-terminus
chr1	950030	952882	-	DDB_G0267416	rpmA	nuclear gene encoding the mitochondrial RNA polymerase
chr1	954390	958768	+	DDB_G0267840	DDB_G0267840	NA
chr1	959377	960403	+	DDB_G0267842	DDB_G0267842	belongs to the NADP_Rossman superfamily%3B similar to human NMRAL1%3B A. nidulans nmrA is a transcriptional regulator involved in nitrogen metabolite repression
chr1	961152	962309	+	DDB_G0267844	expl6	similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B contains a predicted signal peptide
chr1	962846	963926	+	DDB_G0267846	expl1	similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B contains a predicted signal peptide
chr1	964384	965467	+	DDB_G0267848	DDB_G0267848	NA
chr1	965758	967822	+	DDB_G0267850	DDB_G0267850	NA
chr1	968117	968896	-	DDB_G0267852	DDB_G0267852	the Maf protein is a putative inhibitor of septum formation found in eukaryotes%2C bacteria%2C and archaea
chr1	970209	973782	+	DDB_G0267854	gxcD	multi-domain protein with similarity to Rho guanine nucleotide exchange factors
chr1	974099	976591	+	DDB_G0267856	DDB_G0267856	NA
chr1	977722	980295	+	DDB_G0267858	DDB_G0267858	NA
chr1	980835	983272	+	DDB_G0268362	DDB_G0268362	NA
chr1	983481	984122	-	DDB_G0267860	DDB_G0267860	NA
chr1	984537	985406	+	DDB_G0267862	DDB_G0267862	no known homolog 
chr1	985707	986657	-	DDB_G0267864	DDB_G0267864	NA
chr1	986994	989265	+	DDB_G0268364	DDB_G0268364	NA
chr1	989851	991118	+	DDB_G0268366	DDB_G0268366	NA
chr1	991453	992043	-	DDB_G0267866	DDB_G0267866	putative ortholog of H. sapiens POMP%3B similar to S. cerevisiae UMP1 involved in maturation of the 20S proteasome
chr1	992499	994469	-	DDB_G0267868	DDB_G0267868	NA
chr1	995736	996910	+	DDB_G0267870	rnf113	similar to human RING finger proteins RNF113A and RNF113B
chr1	1000903	1001043	-	DDB_G0268370	DDB_G0268370	NA
chr1	1003245	1006160	+	DDB_G0268368	mybAA	contains three Myb DNA-binding domains
chr1	1007048	1009918	+	DDB_G0268374	dcd2B	NA
chr1	1010098	1012044	-	DDB_G0268472	naprt	catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%2C which elevates cellular NAD levels and prevent oxidative stress
chr1	1012281	1014423	-	DDB_G0267872	DDB_G0267872	conserved protein containing a Sun%2Feukaryotic nucleolar NOL1%2FNop2p domain
chr1	1014659	1015216	-	DDB_G0268534	DDB_G0268534	NA
chr1	1015824	1016551	+	DDB_G0268376	DDB_G0268376	NA
chr1	1016994	1019162	+	DDB_G0267874	DDB_G0267874	NA
chr1	1020423	1022453	+	DDB_G0268536	DDB_G0268536	NA
chr1	1022895	1023978	+	DDB_G0268538	psmA5	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr1	1024145	1024917	-	DDB_G0267876	DDB_G0267876	similar to D. purpureum protein%3B contains one coiled-coil domain
chr1	1025189	1028129	+	DDB_G0267878	DDB_G0267878	NA
chr1	1028328	1028897	+	DDB_G0267880	DDB_G0267880	similar to bacterial and fungal acetyltransferases%3B member of the GNAT family
chr1	1029261	1031066	-	DDB_G0267882	DDB_G0267882	NA
chr1	1032061	1034001	-	DDB_G0267884	alg12	CAZy family GT22%3B catalyzes N-linked mannosylation
chr1	1034624	1036114	+	DDB_G0267424	amtC	similar to Arabidopsis AMT1%2C involved in transporting ammonia in the environment into the cell%3B contains 11 transmembrane domains
chr1	1036314	1038005	-	DDB_G0267886	DDB_G0267886	NA
chr1	1038511	1042005	-	DDB_G0267888	DDB_G0267888	NA
chr1	1042896	1044435	-	DDB_G0267890	DDB_G0267890	NA
chr1	1045342	1047918	-	DDB_G0267892	DDB_G0267892	NA
chr1	1051356	1052030	-	DDB_G0267894	DDB_G0267894	NA
chr1	1052627	1053253	-	DDB_G0267896	DDB_G0267896	NA
chr1	1053842	1055149	-	DDB_G0267898	DDB_G0267898	contains two EGF (epidermal growth factor) repeats%3B expressed in pstAB cells
chr1	1056562	1067586	-	DDB_G0302588	DDB_G0302588	similar to a D. purpureum protein
chr1	1071888	1074531	+	DDB_G0267902	DDB_G0267902	NA
chr1	1076498	1076890	+	DDB_G0268382	DDB_G0268382	NA
chr1	1077141	1080667	-	DDB_G0267904	DDB_G0267904	putative ortholog of Xenopus AND-1 (Acidic Nucleoplasmic DNA-binding protein 1) that participates in loading the MCM2-7 helicase complex at the initiation of DNA replication %3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0267904 is a wd-repeat protein with moderate similarity to AND-1%2C also known as CTF4%2C a wd40 and HMG-box containing protein originally discovered in Xenopus. (see Franke et al%2C AND-1%2C a natural chimeric DNA-binding protein%2C combines an HMG-box with regulatory WD-repeats.Journal of Cell Science 110%2C 1051-1062) AND-1%2FCTF4 participates in loading the MCM2-7 helicase complex at the initiation of DNA replication (see Zhu et al%2C Genes and Development 21%2C 2288-2299 (2007)%2C also Tanaka et al%2C Genes to Cells 14%2C 807-20 (2009). Recent work suggests that AND-1%2FCTF4 links sister chromatid cohesion with DNA replication(see Tanaka et al%2C Genes to Cells 14%2C 991-1001 (2009).%3Cbr%3E DDB G0267904 is overexpressed 12-fold [1299 hits to 99%3B p%3C1e-210] in a Dicty strain lacking the retinoblastoma-like gene rblA. Most genes associated with cell cycle progression are overexpressed in these cells (Doquang et al%2C in preparation). The overexpression factor for DDB_GO267904 is similar to that observed for the MCM subunits%2C as well as DNA polymerase alpha%2C delta and episilon subunits. %3Ci%3EHarry MacWilliams%2C August 2009%3C%2Fi%3E
chr1	1080926	1082242	-	DDB_G0267906	DDB_G0267906	related to the Ovarian Tumour (OTU) gene of Drosophila%3B function is unknown but conserved cysteine and histidine%2C and possibly the aspartate%2C residues suggests that those not yet recognized as peptidases could possess cysteine protease activity
chr1	1083269	1083568	+	DDB_G0267908	DDB_G0267908	NA
chr1	1084166	1085446	+	DDB_G0267476	sigK	regulated by the MADS-box transcription factor SrfA during development%3B expressed in stalk cells%3B contains two EGF domains
chr1	1085918	1089019	+	DDB_G0268384	DDB_G0268384	NA
chr1	1089190	1090568	-	DDB_G0268540	ugt2	CAZy family GT28%3B highly similar to ugt3
chr1	1091218	1091622	+	DDB_G0268542	DDB_G0268542	NA
chr1	1091709	1093085	-	DDB_G0268544	ugt3	CAZy family GT28%3B highly similar to ugt2
chr1	1093913	1094419	-	DDB_G0267412	pspA	expressed in prespore cells%3B structurally similar to ponticulins
chr1	1095713	1096937	-	DDB_G0268546	DDB_G0268546	NA
chr1	1099622	1104015	+	DDB_G0268548	pikF	putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring%3B has the capacity to bind and be activated by the GTP-bound small GTPase ras
chr1	1104198	1106228	-	DDB_G0268386	DDB_G0268386	similar to D. purpureum protein%3B contains one SET domain and one tetratricopeptide repeat (TPR) region
chr1	1106720	1108333	-	DDB_G0267910	DDB_G0267910	NA
chr1	1108930	1110561	-	DDB_G0268388	DDB_G0268388_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0267968%22%3EDDB_G0267968%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0268554%22%3EDDB_G0268554%3C%2Fa%3E 
chr1	1110833	1112369	-	DDB_G0268390	DDB_G0268390_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0268554%22%3EDDB_G0268554%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0267968%22%3EDDB_G0267968%3C%2Fa%3E
chr1	1112700	1114253	-	DDB_G0267914	DDB_G0267914	NA
chr1	1114621	1117968	-	DDB_G0267916	mtmr15	conserved eukaryotic protein%3B contains a C-terminal VRR-NUC domain %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  Not a great deal seems to be known about this protein%2C other than the fact that the myotubularin family encodes dual-specificity phosphatases. Myotubularin itself is mutated in X-linked myotubular myopathy.  Dicty Mtmr15 is overexpressed sixfold in a Dicty strain lacking the  retinoblastoma-like gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E  (Doquang et al%2C in preparation). Most genes involved in cell cycle progression are  overexpressed in this strain%2C and this suggests that mtmr15 has a cell cycle function.  Dicty mtmr15 has%2C at the N-terminus%2C a bipartite NLS and a canonical PIP (PCNA-interacting-protein) domain.  This is consistent with a function of mtmr15 in DNA replication in the immediate vicinity of the replication fork. One possibility could be the dephosphorylation of rad9%2C which is a member of the PCNA-like 9-1-1 clamp complex. The rad9 C-terminus is phosphorylated in response to DNA damage%2C and dephosphorylation is necessary to allow cell cycle progression. All of the members of the 9-1-1 complex and its loader (rad9%2C rad1%2C hus1%2C rad17%2C rfc2-5) are overexpressed in the rblA null. %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Fmtmr15%22%3E There is more information on the wiki page%3C%2Fa%3E.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C September 2009 %3C%2Fi%3E  
chr1	1118591	1121104	+	DDB_G0267918	DDB_G0267918	NA
chr1	1121667	1122038	+	DDB_G0267920	DDB_G0267920	NA
chr1	1122624	1123895	+	DDB_G0267466	cupA	highly conserved protein family up-regulated by Ca2%2B%3B expressed throughout vegetative cells and in the cortex of aggregating cells%3B downstream ORF is potentially part of this gene
chr1	1125084	1126553	-	DDB_G0267922	DDB_G0267922_ps	putative pseudogene%3B fragment%2C similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0267938%22%3EDDB_G0267938%3C%2Fa%3E
chr1	1128799	1132710	+	DDB_G0267924	DDB_G0267924	catalyzes the reaction ATP %2B H%3Csub%3E2%3C%2Fsub%3EO %2B Na%3Csup%3E%2B%3C%2Fsup%3E%2Fin %2B K%3Csup%3E%2B%3C%2Fsup%3E%2Fout %3D ADP %2B phosphate %2B Na%3Csup%3E%2B%3C%2Fsup%3E%2Fout %2B K%3Csup%3E%2B%3C%2Fsup%3E%2Fin%3B %3Cbr%2F%3E contains 10 transmembrane domains
chr1	1135912	1139439	+	DDB_G0268394	DDB_G0268394	NA
chr1	1139853	1140479	-	DDB_G0268396	sep15	contains a selenocysteine residue (U) at position 100%3B conserved protein%2C which may be involved in protein folding in the endoplasmic reticulum
chr1	1141518	1142703	+	DDB_G0267928	tmem144B	similar to human TMEM144%3B contains 10 predicted transmembrane domains
chr1	1143814	1144065	+	DDB_G0267930	DDB_G0267930	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr1	1145056	1145211	+	DDB_G0267932	DDB_G0267932	NA
chr1	1145507	1147336	-	DDB_G0268550	DDB_G0268550	kinase domain similar to those of mitogen-activated protein kinases%3B similar to the STE20 family
chr1	1147906	1149691	-	DDB_G0267934	fnkB	similar to mammalian CHK1 and to other Dictyostelium FNIP repeat-containing proteins
chr1	1150368	1150689	-	DDB_G0268398	DDB_G0268398	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268400%22%3E%3Ci%3EDDB_G0268400%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0267936%22%3E%3Ci%3EDDB_G0267936%3C%2Fi%3E%3C%2Fa%3E 
chr1	1151178	1151529	-	DDB_G0268400	DDB_G0268400	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268398%22%3E%3Ci%3EDDB_G0268398%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0267936%22%3E%3Ci%3EDDB_G0267936%3C%2Fi%3E%3C%2Fa%3E 
chr1	1152289	1152619	+	DDB_G0267936	DDB_G0267936	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268398%22%3E%3Ci%3EDDB_G0268398%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268400%22%3E%3Ci%3EDDB_G0268400%3C%2Fi%3E%3C%2Fa%3E
chr1	1153178	1156723	+	DDB_G0267938	DDB_G0267938	NA
chr1	1157427	1158481	-	DDB_G0268402	rab24	similar to rab24
chr1	1159902	1161696	+	DDB_G0267940	DDB_G0267940	NA
chr1	1161933	1165193	-	DDB_G0267942	DDB_G0267942	NA
chr1	1167122	1167316	+	DDB_G0267946	DDB_G0267946	NA
chr1	1168646	1170444	-	DDB_G0267452	sonA	NA
chr1	1170991	1172151	-	DDB_G0267948	ccdc53	NA
chr1	1172814	1173875	+	DDB_G0267950	copE	epsilon subunit of the coatomer complex essential for the secretory pathway
chr1	1173990	1175066	-	DDB_G0267952	DDB_G0267952	NA
chr1	1175758	1177189	+	DDB_G0267954	DDB_G0267954	contains a C-terminal Bicoid-interacting 3 domain%2C which occurs in methyltransferases that modify RNA-binding proteins%3B has similarity to mammalian 7SK snRNA methylphosphate capping enzyme 
chr1	1177308	1178404	-	DDB_G0267956	abiA	similar to Abi2%2C Abl-interactor 2
chr1	1179370	1181659	+	DDB_G0267958	DDB_G0267958	NA
chr1	1182084	1184169	+	DDB_G0268552	DDB_G0268552	NA
chr1	1184694	1187746	+	DDB_G0268404	DDB_G0268404	DENN domains are present in proteins involved in Rab signaling
chr1	1187972	1190807	-	DDB_G0267960	cog4	highly similar to COG4%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits
chr1	1191800	1198906	+	DDB_G0267962	tsuA	putative protein serine%2Fthreonine kinase%3B similar to mammalian STK36 and fly fused kinase (fu)%2C a S%2FT kinase involved in the hedgehog signal transduction pathway%3B belongs to the ULK (Unc-51-like kinase) family of kinases
chr1	1199077	1199454	-	DDB_G0267964	DDB_G0267964	NA
chr1	1199961	1201386	+	DDB_G0267474	sigD	developmentally regulated gene whose expression is dependent on MADS Box transcription factor srfA
chr1	1202711	1205883	+	DDB_G0267966	pyd1	ortholog of S. cerevisiae URA1 and human DPYD%3B defects in DPYD cause dihydropyrimidine dehydrogenase deficiency%3B catalyzes the reaction 5%2C6-dihydrouracil %2B NADP%2B %3C%3D%3E uracil %2B NADPH %2B H%2B
chr1	1206080	1206733	-	DDB_G0268406	DDB_G0268406	weak similarity to fungal profilins
chr1	1207158	1209051	+	DDB_G0267968	DDB_G0267968	NA
chr1	1209177	1209413	-	DDB_G0267970	DDB_G0267970	NA
chr1	1209766	1211808	+	DDB_G0268554	DDB_G0268554	NA
chr1	1212494	1213977	+	DDB_G0268408	DDB_G0268408_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0267968%22%3EDDB_G0267968%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0268554%22%3EDDB_G0268554%3C%2Fa%3E 
chr1	1214003	1217095	-	DDB_G0267974	DDB_G0267974	NA
chr1	1217963	1219191	-	DDB_G0267976	aph1	component of the gamma-secretase complex%2C which executes the intramembrane proteolysis of type I integral membrane proteins
chr1	1220851	1224573	+	DDB_G0267978	krsB	putative protein serine%2Fthreonine kinase%3B N-terminus similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B C-terminal half belongs to the peptidase C2 family and contains 4 calpain III domains
chr1	1225333	1229934	+	DDB_G0268410	drnB	similar to the mammalian Dicer protein%2C an RNase III protein that converts long dsRNA (double-stranded RNA) into siRNA (small interfering RNA)%3B in %3Ci%3EDictyostelium%3C%2Fi%3E involved in RNA interference and microRNA processing
chr1	1230144	1231512	-	DDB_G0267980	mocs3	NA
chr1	1232234	1235989	+	DDB_G0267982	copA	contains five WD40 repeats%3B alpha subunit of the coatomer complex essential for the secretory pathway
chr1	1236115	1237782	-	DDB_G0267984	DDB_G0267984	conserved peptidase M20 family zinc metallopeptidases%2C which are glutamate carboxypeptidases%3B contains peptidase dimerization domain
chr1	1238363	1240237	+	DDB_G0267986	DDB_G0267986	NA
chr1	1240356	1241711	-	DDB_G0267988	DDB_G0267988	NA
chr1	1242726	1243286	-	DDB_G0267990	ypel	single %3Ci%3ED. discoideum%3C%2Fi%3E ortholog of the highly conserved yippee protein family
chr1	1244589	1245377	-	DDB_G0267992	DDB_G0267992	weakly similar to cyclin-dependent kinase inhibitor 3 (CDNK3)
chr1	1246116	1247617	-	DDB_G0267994	DDB_G0267994	similar to a large family of eukaryotic DNAJ heat shock proteins (DnaJ Hsp40)
chr1	1248279	1249587	+	DDB_G0267996	DDB_G0267996	NA
chr1	1250161	1252599	-	DDB_G0267406	lmpA	belongs to the CD36 family%3B contains two transmembrane domains
chr1	1253447	1257146	+	DDB_G0268412	DDB_G0268412	NA
chr1	1257306	1259874	-	DDB_G0267440	lmpC	NA
chr1	1260113	1262650	+	DDB_G0267434	DDB_G0267434	NA
chr1	1263019	1266447	+	DDB_G0267436	abcF4	consists of two ABC domains and lacks a transmembrane domain
chr1	1266897	1271013	+	DDB_G0295829	DDB_G0295829	contains a signal peptide and a C-terminal transmembrane domain
chr1	1271527	1273446	+	DDB_G0268556	psiE	contains a signal peptide and a PA14 domain
chr1	1274009	1275386	+	DDB_G0267998	psiS	contains a signal peptide%3B similar to PsiA and related  proteins%2C but missing the carboxyl terminus compared to similar proteins
chr1	1276791	1278869	+	DDB_G0268000	psiB	contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C and 5 Dictyostelium (CTDC) repeats
chr1	1279173	1280558	+	DDB_G0268002	DDB_G0268002_ps	putative pseudogene%3B very similar to %3Ci%3EDictyostelium%3C%2Fi%3E PA14 domain-containing proteins
chr1	1280990	1283391	-	DDB_G0267400	hspD	NA
chr1	1286207	1287863	+	DDB_G0268004	snrp70	ortholog of human SNRP70%2C a component of the U1 snRNP involved in mRNA splicing
chr1	1288689	1289290	-	DDB_G0268006	DDB_G0268006	NA
chr1	1290599	1291894	-	DDB_G0268008	DDB_G0268008	very similar to bacterial FAD dependent oxidoreductases
chr1	1292814	1294391	+	DDB_G0268558	DDB_G0268558	NA
chr1	1295307	1299499	-	DDB_G0268420	DDB_G0268420	NA
chr1	1301596	1302485	+	DDB_G0268010	DDB_G0268010	NA
chr1	1302705	1303853	-	DDB_G0268012	DDB_G0268012	contains an RR domain found in two-component signal transduction systems
chr1	1308296	1310389	+	DDB_G0268014	gtf2h1	ortholog of S. cerevisiae TFB1%2C subunit of TFIIH and nucleotide excision repair factor 3 complexes%2C required for nucleotide excision repair%2C target for transcriptional activators
chr1	1310839	1313118	+	DDB_G0267444	phg1A	involved in phagocytosis and substrate adhesion%3B controls the levels of SibA adhesion molecules at the cell surface as well as the intracellular transport and stability of the SibA protein%3B also involved in the intracellular killing of bacteria by determining the stability and cellular amount of the sulfotransferase Kil1%3Cbr%3E %3Cb%3ENomenclature conflict: %3C%2Fb%3E Do not confuse this gene with phgA%2C encoding drainin%2C or with the phgA locus (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Freference%2Freference.pl?refNo%3D1446%22%3EDuffy and Vogel 1984%3C%2Fa%3E)
chr1	1313476	1313789	-	DDB_G0268016	DDB_G0268016	NA
chr1	1314808	1316513	+	DDB_G0268018	DDB_G0268018	NA
chr1	1317002	1318564	+	DDB_G0268020	bkdB	catalyzes the reaction 3-methyl-2-oxobutanoate %2B lipoamide %3D S-(2-methylpropanoyl)-dihydrolipoamide %2B CO%3Csub%3E2%3C%2Fsub%3E%3B E1 component of branched-chain keto acid dehydrogenase
chr1	1318763	1319387	-	DDB_G0268022	DDB_G0268022	NA
chr1	1320084	1322172	-	DDB_G0268024	hdaA	catalyzes the removal of an acetyl group from lysine
chr1	1322688	1323508	-	DDB_G0268026	DDB_G0268026	contains 4 putative transmembrane domains%3B similar to D. purpureum protein
chr1	1325279	1327600	-	DDB_G0268028	DDB_G0268028	expressed in prespore cells
chr1	1329298	1331157	+	DDB_G0267386	cysB	catalyzes the reaction homocysteine %2B L-serine %3C%3D%3E H%3Csub%3E2%3C%2Fsub%3EO %2B cystathionine
chr1	1331239	1333035	-	DDB_G0267392	plbG	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276767%22%3E%3Ci%3EplbA%3C%2Fi%3E%3C%2Fa%3E%2C which catalyzes the hydrolysis of phosphatidylcholine to glycerophosphocholine
chr1	1334449	1338114	-	DDB_G0268030	DDB_G0268030	NA
chr1	1339034	1339901	+	DDB_G0268422	DDB_G0268422	NA
chr1	1340557	1342081	+	DDB_G0268034	DDB_G0268034	homolog of mammalian Rab GDP dissociation inhibitor alpha%3B forms a soluble complex with Rab proteins%2C thereby preventing exchange of GDP for GTP
chr1	1342458	1343261	+	DDB_G0268036	DDB_G0268036	bifunctional enolase-phosphatase that cleaves the substrates 2%2C3-diketo-5-methylthio-1-phosphopentane and 2-hydroxy-3-keto-5-methylthio-1-phosphopentene
chr1	1344276	1344767	+	DDB_G0268038	mtpn	Ortholog of metazoan myotrophin (MTPN)%2C which might be involved in cerebellar morphogenesis and cardiac hypertrophy%3B contains 2 ankyrin repeats
chr1	1345125	1346305	+	DDB_G0268040	DDB_G0268040	NA
chr1	1346481	1347356	-	DDB_G0268042	DDB_G0268042	The CS domain may be involved in protein-protein interactions
chr1	1347890	1351635	-	DDB_G0268044	DDB_G0268044	NA
chr1	1352853	1352990	+	DDB_G0268046	DDB_G0268046	NA
chr1	1353351	1354182	-	DDB_G0268048	DDB_G0268048	conserved protein of unknown function
chr1	1354807	1355529	-	DDB_G0268050	DDB_G0268050	NA
chr1	1355835	1359552	-	DDB_G0268560	DDB_G0268560	the SWIM domain is found in variety of prokaryotic and eukaryotic proteins%3B it is predicted to have DNA-binding and protein-protein interaction functions in different contexts%3B also contains a P-loop motif and region of tetrapeptide XPTX repeats%3B similar to D. purpureum protein
chr1	1359896	1363000	-	DDB_G0268052	DDB_G0268052	NA
chr1	1365318	1365947	-	DDB_G0268054	DDB_G0268054	NA
chr1	1366267	1368004	-	DDB_G0268056	sptA	similar to S. cerevisiae LCB1%3B dimerizes with SptB to catalyze the conversion of palmitoyl-CoA %2B L-serine into CoA %2B 3-dehydro-D-sphinganine %2B CO%3Csub%3E2%3C%2Fsub%3E
chr1	1368763	1370695	-	DDB_G0268424	DDB_G0268424	NA
chr1	1371493	1372547	-	DDB_G0268058	alrC	member of aldo-keto reductase family%2C which reduces C%3DO to C-OH in aldehydes and ketones
chr1	1373976	1374748	-	DDB_G0268562	alr_ps	putative pseudogene%3B similar to aldo-keto reductases alrA-F
chr1	1375259	1376890	+	DDB_G0268426	zntA	ZIP family zinc transporter%2C LZT subfamily member%3B contains 8 transmembrane domains%3B expressed in pstAB cells
chr1	1377494	1378332	+	DDB_G0268564	DDB_G0268564	putative ortholog of peroxisomal membrane protein PXMP4
chr1	1378934	1380740	+	DDB_G0268566	DDB_G0268566	NA
chr1	1380972	1383578	-	DDB_G0268060	DDB_G0268060	NA
chr1	1385036	1385981	+	DDB_G0267378	aqpA	similar to aquaporin family of water-channel proteins%3B expressed in prespore cells
chr1	1387513	1387930	+	DDB_G0268568	DDB_G0268568_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289399%22%3EDDB_G0289399%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0287667%22%3EDDB_G0287667%3C%2Fa%3E
chr1	1390845	1390949	+	DDB_G0348179	DDB_G0348179	NA
chr1	1391482	1393242	+	DDB_G0268062	DDB_G0268062	NA
chr1	1393387	1394274	-	DDB_G0268064	DDB_G0268064	conserved hypothetical protein
chr1	1394864	1397458	+	DDB_G0268066	DDB_G0268066	NA
chr1	1398472	1399280	+	DDB_G0268068	rab6	similar to M. musculus rab6A
chr1	1399546	1400979	-	DDB_G0268070	DDB_G0268070	NA
chr1	1402456	1404546	+	DDB_G0268428	DDB_G0268428	NA
chr1	1404967	1408062	+	DDB_G0268072	DDB_G0268072	NA
chr1	1408319	1411401	-	DDB_G0268074	DDB_G0268074	NA
chr1	1414125	1415255	-	DDB_G0268076	DDB_G0268076	NA
chr1	1417972	1419590	+	DDB_G0268078	DDB_G0268078	putative ortholog of human ICK (intestinal cell (MAK-like) kinase) and mouse MAK (male germ cell-associated kinase)
chr1	1420168	1422262	+	DDB_G0268080	rpc3	component of the RNA polymerase III complex%3B has similarity to H. sapiens RPC3%2FRPC62 and S. cerevisiae RPC82
chr1	1423638	1426439	+	DDB_G0268430	DDB_G0268430	NA
chr1	1428341	1428634	+	DDB_G0268082	DDB_G0268082	NA
chr1	1428913	1431383	-	DDB_G0268084	wdr91	conserved protein containing 5 to 7 WD40 repeats
chr1	1432461	1432727	+	DDB_G0268086	DDB_G0268086	NA
chr1	1432947	1439629	-	DDB_G0268088	lvsG	protein with a beige%2FBEACH domain%2C a weak protein kinase domain%2C and N-terminal WD40 repeats%3B does not contain the consensus sequences required for kinase function
chr1	1440159	1441186	-	DDB_G0268090	DDB_G0268090	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr1	1443157	1444962	+	DDB_G0267428	abcH2	consists of one ABC domain and lacks a transmembrane domain
chr1	1445229	1445868	-	DDB_G0268092	DDB_G0268092	similar to human Zinc finger SWIM domain-containing protein 7%2C a regulator of homologous recombination in eukaryotic cells
chr1	1446577	1447961	+	DDB_G0268094	DDB_G0268094	NA
chr1	1448032	1449683	-	DDB_G0268096	DDB_G0268096	NA
chr1	1449845	1449909	+	DDB_G0295487	r28	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr1	1450677	1452718	-	DDB_G0268098	nop58	ortholog of human and S. pombe nucleolar protein 58%3B members of this family are involved in a variety of functions during pre-mRNA splicing
chr1	1453036	1454418	-	DDB_G0268100	asnS2	catalyzes the reaction ATP %2B L-asparagine %2B tRNAAsn %3D AMP %2B diphosphate %2B L-asparaginyl-tRNAAsn%3B similar to bacterial Asn-tRNA-ligases
chr1	1455102	1460921	+	DDB_G0268102	DDB_G0268102	NA
chr1	1461475	1463206	+	DDB_G0268104	gabT	catalyzes the degradation of GABA :4-aminobutanoate %2B 2-oxoglutarate %3D succinate semialdehyde %2B L-glutamate%3B null mutant has a very mild developmental delay 
chr1	1463479	1463865	-	DDB_G0268106	DDB_G0268106	NA
chr1	1465335	1466195	+	DDB_G0268108	DDB_G0268108	similar to D. purpureum protein
chr1	1466318	1468006	-	DDB_G0268110	DDB_G0268110	NA
chr1	1468365	1468964	+	DDB_G0268112	DDB_G0268112	lysine and glutamine rich protein
chr1	1469084	1473264	-	DDB_G0267464	polA	contains one 5%27-3%27 exonuclease domain and one 3%27-5%27 exonuclease domain
chr1	1473867	1474392	+	DDB_G0268114	DDB_G0268114	NA
chr1	1475254	1478148	-	DDB_G0268432	DDB_G0268432	NA
chr1	1478649	1478854	-	DDB_G0295489	rnu2c	component of the spliceosome involved in pre-mRNA splicing
chr1	1479198	1479403	+	DDB_G0295491	rnu2a	component of the spliceosome involved in pre-mRNA splicing
chr1	1479679	1480888	-	DDB_G0268116	DDB_G0268116	similarity to Xenopus F8A1 protein%2C human Factor VIII intron 22 protein
chr1	1481369	1483750	+	DDB_G0268118	DDB_G0268118	NA
chr1	1483803	1484696	-	DDB_G0268120	DDB_G0268120_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268434%22%3E DDB_G0268434%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0268122%22%3EDDB_G0268122%3C%2Fa%3E
chr1	1485131	1485859	-	DDB_G0268434	DDB_G0268434	NA
chr1	1487041	1487541	-	DDB_G0268122	DDB_G0268122	NA
chr1	1488450	1489057	-	DDB_G0268124	DDB_G0268124_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268434%22%3E DDB_G0268434%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0268122%22%3EDDB_G0268122%3C%2Fa%3E
chr1	1489512	1491326	-	DDB_G0268126	DDB_G0268126	ortholog of human HPS4%3B mutations in human HPS4 have been linked to Hermansky-Pudlak syndrome 4
chr1	1491471	1491797	+	DDB_G0268438	DDB_G0268438	NA
chr1	1492031	1493941	+	DDB_G0268570	DDB_G0268570	NA
chr1	1494431	1506056	+	DDB_G0267422	tipC	similar to S. cerevisiae VPS13 involved in vacuolar protein sorting and protein-Golgi retention%3B in D. discoideum involved in early development and tip formation
chr1	1506583	1507224	-	DDB_G0268440	DDB_G0268440_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1507711	1507902	-	DDB_G0268128	DDB_G0268128_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1508042	1508128	-	DDB_G0294823	tRNA-Trp-CCA-5	transfers a tryptophan residue to a growing polypeptide chain during protein synthesis%0A
chr1	1509432	1510298	+	DDB_G0268442	DDB_G0268442	NA
chr1	1511351	1511437	-	DDB_G0294821	tRNA-Trp-CCA-4	transfers a tryptophan residue to a growing polypeptide chain during protein synthesis%0A
chr1	1512409	1514206	+	DDB_G0268130	DDB_G0268130	NA
chr1	1514264	1515878	-	DDB_G0268444	DDB_G0268444	NA
chr1	1516724	1519586	+	DDB_G0268132	DDB_G0268132	contains a SET domain involved in histone methylation%2C an AWS (Associated With SET) domain%2C and a post-SET zinc-binding domain
chr1	1520754	1521173	+	DDB_G0267402	H3a	component of the H2A-H2B-H3-H4 histone octamer%3B dimerizes with histone H4
chr1	1521691	1526501	+	DDB_G0268134	DDB_G0268134	NA
chr1	1527025	1528102	+	DDB_G0268136	DDB_G0268136	NA
chr1	1528262	1528973	+	DDB_G0268138	DDB_G0268138	catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione
chr1	1529143	1531470	-	DDB_G0268140	DDB_G0268140	NA
chr1	1532259	1533436	+	DDB_G0268142	DDB_G0268142	NA
chr1	1533586	1535463	-	DDB_G0268144	vwkA	belongs to the Atypical Alpha protein kinases and contains a von Willebrand factor%2C type A (VWFA) domain%3B does not phosphorylate myosin heavy chain
chr1	1536630	1537772	+	DDB_G0268146	DDB_G0268146	NA
chr1	1538303	1539435	+	DDB_G0268148	DDB_G0268148	NA
chr1	1539632	1539916	+	DDB_G0268150	DDB_G0268150_ps	putative pseudogene%3B fragment%2C similar to a small family of Dictyostelium genes%2C including the upstream %3Ca href%3D%22%2Fgene%2FDDB_G0268146%22%3EDDB_G0268146%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0268148%22%3EDDB_G0268148%3C%2Fa%3E
chr1	1540789	1542162	+	DDB_G0268446	cbhA	NA
chr1	1542257	1544719	-	DDB_G0268152	DDB_G0268152	NA
chr1	1545975	1546631	+	DDB_G0268154	DDB_G0268154	NA
chr1	1546946	1548173	-	DDB_G0268448	fam45	conserved protein 
chr1	1548695	1550155	-	DDB_G0268156	tsin	NA
chr1	1551637	1554960	+	DDB_G0268572	DDB_G0268572	NA
chr1	1556730	1557482	+	DDB_G0268574	eIF4e	EIF4E ortholog%2C the eukaryotic initiation factor 4E%3B recognizes and binds the RNA cap during protein synthesis
chr1	1558253	1561540	+	DDB_G0268576	DDB_G0268576	NA
chr1	1563062	1569010	+	DDB_G0268578	gefV	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form%3B contains a RasGEF domain and 10 leucine-rich repeats
chr1	1569279	1571100	-	DDB_G0267426	cshA	catalyzes the condensation of acetyl-CoA and oxaloacetate to citrate
chr1	1574564	1576904	+	DDB_G0268158	DDB_G0268158	shares a short region of similarity with Wolf-Hirschhorn syndrome candidate 1 protein
chr1	1577150	1578881	-	DDB_G0268160	gnt12	CAZy family GT49%3B similar to vertebrate acetylglucosaminyltransferase-like protein
chr1	1580521	1581951	+	DDB_G0268162	DDB_G0268162	NA
chr1	1582311	1583530	-	DDB_G0267442	cdk8	controls RNA polymerase II activity by phosphorylating the carboxy terminal domain (CTD) of the largest subunit%3B predicted to interact with %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2F%2Fgene_page.pl?gene_name%3DcycC%22%3Ecyclin C%3C%2Fa%3E%3B belongs to the protein kinase superfamily%2C CMGC Ser%2FThr protein kinase family%2C CDC2%2FCDKX subfamily.
chr1	1584255	1586243	+	DDB_G0268164	DDB_G0268164	NA
chr1	1586565	1588451	+	DDB_G0268450	DDB_G0268450	NA
chr1	1588545	1589537	-	DDB_G0268452	DDB_G0268452	putative ortholog of mammalian Golgi SNAP receptor complex member 2
chr1	1590745	1591284	+	DDB_G0268166	DDB_G0268166	similar to uncharacterized bacterial and eukaryotic proteins of the cupin_5 family%3B also predicted to have an RmlC-like jelly roll fold 
chr1	1591385	1593342	-	DDB_G0268168	png	belongs to the transglutaminase-like superfamily%3B involved in the degradation of misfolded glycosylated proteins%3B required for normal multicellular development and plays a role in prespore cell differentiation
chr1	1593660	1594019	-	DDB_G0268170	DDB_G0268170	NA
chr1	1594682	1595023	-	DDB_G0268454	DDB_G0268454	weakly similar to hssA%2F2C%2F7E family genes%3B expression positively regulated by STATa
chr1	1595915	1596310	-	DDB_G0268456	DDB_G0268456	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268172%22%3E%3Ci%3EDDB_G0268172%3C%2Fi%3E%3C%2Fa%3E%3B expression positively regulated by STATa
chr1	1596761	1597122	-	DDB_G0268172	DDB_G0268172	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268456%22%3E%3Ci%3EDDB_G0268456%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268174%22%3E%3Ci%3EDDB_G0268174%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268458%22%3E%3Ci%3EDDB_G0268458%3C%2Fi%3E%3C%2Fa%3E 
chr1	1597570	1597918	-	DDB_G0268174	DDB_G0268174	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268172%22%3E%3Ci%3EDDB_G0268172%3C%2Fi%3E%3C%2Fa%3E 
chr1	1598476	1598890	-	DDB_G0268458	DDB_G0268458	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268456%22%3E%3Ci%3EDDB_G0268456%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268174%22%3E%3Ci%3EDDB_G0268174%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268172%22%3E%3Ci%3EDDB_G0268172%3C%2Fi%3E%3C%2Fa%3E
chr1	1599584	1600147	-	DDB_G0268460	ponK	structurally similar to ponticulins
chr1	1600589	1602124	-	DDB_G0268176	DDB_G0268176	NA
chr1	1602467	1603407	+	DDB_G0268178	jcdB	NA
chr1	1603473	1607291	-	DDB_G0267410	pslA	nuclear protein%3B possible transcription factor%3B contains a possible ankyrin repeat region
chr1	1607815	1609553	-	DDB_G0267398	gppA	NA
chr1	1611083	1614376	-	DDB_G0268580	DDB_G0268580_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	1614526	1615398	-	DDB_G0268582	DDB_G0268582_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	1615509	1615579	-	DDB_G0294819	tRNA-Pro-UGG-6	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr1	1615735	1617831	-	DDB_G0268180	DDB_G0268180	NA
chr1	1618454	1618524	-	DDB_G0294817	tRNA-Pro-UGG-5	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr1	1618791	1619297	+	DDB_G0268182	DDB_G0268182	NA
chr1	1619582	1621263	-	DDB_G0268184	DDB_G0268184	contains a predicted signal peptide
chr1	1622398	1626997	-	DDB_G0268186	DDB_G0268186	NA
chr1	1630091	1632271	+	DDB_G0268462	DDB_G0268462	contains 9 transmembrane domains as predicted by TMHMM2.0
chr1	1632774	1632846	+	DDB_G0294685	tRNA-Asn-GUU-2	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1633311	1636454	+	DDB_G0268188	DDB_G0268188	NA
chr1	1637375	1639913	+	DDB_G0268190	fut11	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr1	1640028	1640576	-	DDB_G0268192	DDB_G0268192	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr1	1641107	1641971	-	DDB_G0268194	DDB_G0268194	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B dCTP -%3E NH3 %2B dUTP in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine deoxyribonucleotides
chr1	1642718	1645146	+	DDB_G0268196	DDB_G0268196	NA
chr1	1645550	1646794	+	DDB_G0268198	rpa43	component of the RNA polymerase I complex%3B ortholog of S. cerevisiae RPA43
chr1	1647348	1648410	+	DDB_G0267374	acpA	32 kDa subunit of heterodimeric actin capping protein cap32%2F34%3B 34 kDa subunit is encoded by acpB%3B contributes to the dynactin complex
chr1	1649497	1653049	+	DDB_G0268584	DDB_G0268584	NA
chr1	1653352	1653765	-	DDB_G0268200	DDB_G0268200	NA
chr1	1654404	1659091	+	DDB_G0268258	kif12	MKLP1 subfamily kinesin%3B required for cell division in suspension and for nuclei separation during karyokinesis%3B localized in the nucleus during interphase%2C and in the centrosome%2C  spindle%2C and spindle midbody during cytokinesis
chr1	1659361	1660037	-	DDB_G0267394	vps46	highly similar to S. cerevisiae DID2 and H. sapiens CHMP1 proteins involved in the vacuolar protein-sorting (Vps) pathway
chr1	1662307	1663602	+	DDB_G0267418	sahA	highly similar to mammalian SAHH (catalyzes the hydrolysis of S-adenosyl-L-homocysteine into adenosine and homocysteine)%3B localizes to actin rods found in spores
chr1	1666540	1667807	-	DDB_G0268586	DDB_G0268586	NA
chr1	1668764	1671736	-	DDB_G0268588	DDB_G0268588	NA
chr1	1672557	1674578	-	DDB_G0268590	DDB_G0268590	NA
chr1	1676402	1680165	+	DDB_G0268592	dlpA	involved in cytokinesis%3B stabilizes actin filaments%3B expressed in pstAB cells and in upper cup during culmination
chr1	1680932	1682389	+	DDB_G0268594	DDB_G0268594	NA
chr1	1682484	1683162	-	DDB_G0268202	DDB_G0268202	NA
chr1	1683897	1685943	+	DDB_G0268204	gnt9	distant relative of CAZy family GT14%3B similar to xylosyltransferase
chr1	1686235	1686317	+	DDB_G0294687	tRNA-Tyr-GUA-2	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1686758	1687651	+	DDB_G0268206	DDB_G0268206	NA
chr1	1688222	1688293	+	DDB_G0294689	tRNA-Thr-AGU-4	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1688502	1689200	+	DDB_G0268596	DDB_G0268596_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1690396	1690910	+	DDB_G0268598	DDB_G0268598_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1691546	1692523	+	DDB_G0268464	DDB_G0268464_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1693320	1693952	+	DDB_G0268208	DDB_G0268208	NA
chr1	1694068	1695156	-	DDB_G0268210	DDB_G0268210	conserved in Dictyostelium and Polysphondylium
chr1	1695570	1696937	-	DDB_G0268212	DDB_G0268212	contains an N-terminal DEAD%2FDEAH box helicase%2C a central helicase associated domain (HA2)%2C and a C-terminal domain of unknown function DUF1605 common to DEAD box helicases
chr1	1697493	1698824	-	DDB_G0268214	enoB	catalyzes the reaction 2-phospho-D-glycerate %3C%3D%3E phosphoenolpyruvate %2B H%3Csub%3E2%3C%2Fsub%3EO
chr1	1700922	1701623	-	DDB_G0268600	uduB	upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr1	1702484	1708162	-	DDB_G0268216	fncD2	ortholog of Fanconi anaemia complementation group D2 protein%2C involved DNA cross-link repair%3B null mutant is sensitive to DNA damaging agents  %3Cbr%2F%3E%3Cbr%2F%3E mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A%2C B%2C C%2C E%2C F%2C G%2C L and M%3B the FA complex interacts with ube2t%2C a E2 ubiquitin-conjugating enzyme%2C to monoubiquitinate  FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the FANCJ helicase as well as FANCN and FANCD1%3B in human%2C mutations in this gene cause Fanconi anaemia%2C an autosomal recessive disorder affecting all bone marrow elements%3B Dictyostelium has orthologs for %3Ca href%3D%22%2Fgene%2FDDB_G0268216%22%3EFANCD2%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0279669%22%3EFANCE%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0292744%22%3EFANCL%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0293476%22%3EFANCI%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0286621%22%3EFANCJ%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274841%22%3EFANCM%3C%2Fa%3E and  %3Ca href%3D%22%2Fgene%2FDDB_G0291199%22%3EUbe2t%3C%2Fa%3E.       %3Cbr%2F%3E%3Cbr%2F%3E   %3Cb%3ECommunity annotation:%3C%2Fb%3E   Fanconi anemia is characterized (among other things) by an increased tumor incidence   and cellular sensitivity to DNA damaging agents. The FanCD2 protein is thought to be a   target of ATM%2FATR kinases activated by double-strand chromosome breaks.   Defects in FANCD2 leads to a failure of the radiation-induced block to DNA   replication.  fancD2 is roughly threefold overexpressed in veg cells of a Dicty strain in which   the retinoblastoma-like gene rblA has been inactivated (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E%2C Doquang et al%2C in preparation). Most genes associated with   cell cycle progression are overexpressed in this strain. In addition%2C the protein   has a mitotic destruction box%2C and is one of 336 known proteins in which this motif   is present in both D discoideum and D purpureum. The context of the element is only   weakly conserved%2C thus the conservation of the R%2C L and N residues in RxxLxxxxN   is particularly suggestive. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C August 2009 %3C%2Fi%3E 
chr1	1708888	1711434	+	DDB_G0268218	DDB_G0268218	NA
chr1	1712183	1713033	+	DDB_G0268220	DDB_G0268220	similar to Ixodes scapularis U2 small nuclear ribonucleoprotein A%2C human c10orf11%3B has 3 leucine-rich repeats which are involved in protein-protein interactions
chr1	1713715	1715167	+	DDB_G0268602	DDB_G0268602	NA
chr1	1715767	1717245	-	DDB_G0268222	DDB_G0268222	belongs to the metallophosphoesterase superfamily%3B similar to human PAPL (Iron%2Fzinc purple acid phosphatase-like protein)%3B contains a predicted signal peptide
chr1	1719500	1721536	-	DDB_G0268224	DDB_G0268224	NA
chr1	1721883	1722152	-	DDB_G0268226	DDB_G0268226	NA
chr1	1723392	1725922	-	DDB_G0268228	DDB_G0268228	NA
chr1	1727069	1728832	+	DDB_G0268230	DDB_G0268230	NA
chr1	1728957	1732034	-	DDB_G0268232	DDB_G0268232	shares a short region of similarity with mammalian Nedd4 binding protein 2%2FBCL-3 binding protein
chr1	1732577	1733416	-	DDB_G0268234	DDB_G0268234	NA
chr1	1733949	1735538	-	DDB_G0268236	DDB_G0268236	NA
chr1	1736097	1737900	-	DDB_G0268238	alg3	CAZy family GT58%3B catalyzes N-linked mannosylation
chr1	1738891	1745341	+	DDB_G0267376	acrA	contains a cyclase domain%2C 7 transmembrane helices%2C a histidine kinase domain%2C and two receiver domains
chr1	1746832	1747104	+	DDB_G0268604	DDB_G0268604	NA
chr1	1747506	1750802	-	DDB_G0267404	kif6	belongs to the MCAK%2FKif2 subfamily%2C contains 1 SAM domain%3B predicted to play a role in mitosis 
chr1	1752059	1754689	+	DDB_G0267462	Dd5P4	inositol 5-phosphatase similar to the human protein OCRL which%2C when defect%2C causes Lowe syndrome%3B involved in %3Ci%3EDictyostelium%3C%2Fi%3E growth%2C development%2C and phagocytosis
chr1	1754914	1755359	-	DDB_G0268240	DDB_G0268240	NA
chr1	1756054	1756317	-	DDB_G0268466	DDB_G0268466	NA
chr1	1758352	1758634	-	DDB_G0295493	srpB	signal recognition particle (SRP) RNA%3B forms the SRP complex with the SRP 72%2C 68%2C 54%2C 19%2C 14%2C and 9 proteins
chr1	1759767	1759839	+	DDB_G0294691	tRNA-Lys-CUU-1	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1760348	1760421	-	DDB_G0294815	tRNA-Arg-ACG-2	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1761068	1763956	+	DDB_G0268244	DDB_G0268244	NA
chr1	1764265	1766742	+	DDB_G0268246	DDB_G0268246	NA
chr1	1766831	1768018	-	DDB_G0268248	DDB_G0268248	NA
chr1	1768454	1769626	-	DDB_G0268250	DDB_G0268250	NA
chr1	1771285	1772395	-	DDB_G0268252	DDB_G0268252	NA
chr1	1773769	1774443	-	DDB_G0268606	DDB_G0268606_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	1775368	1781673	+	DDB_G0268608	DDB_G0268608_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1782218	1783993	+	DDB_G0268610	DDB_G0268610_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1784155	1786338	-	DDB_G0268254	DDB_G0268254_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0274637%22%3EDDB_G0274637%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0274949%22%3EDDB_G0274949%3C%2Fa%3E
chr1	1787018	1788345	-	DDB_G0268612	DDB_G0268612_ps	putative pseudogene%3B similar to a small family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0274631%22%3EDDB_G0274631%3C%2Fa%3E
chr1	1791230	1792357	-	DDB_G0268470	DDB_G0268470_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	1793029	1795373	+	DDB_G0269036	DDB_G0269036_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1795565	1798231	-	DDB_G0268918	DDB_G0268918	NA
chr1	1799319	1801673	+	DDB_G0268640	DDB_G0268640	serine-rich protein very similar to %3Ci%3ErtoA%3C%2Fi%3E%3B contains a putative signal sequence
chr1	1801909	1805309	-	DDB_G0268642	DDB_G0268642	related to the GCN2 family of protein kinases%2C which phosphorylate the alpha subunit of eIF2%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr1	1807927	1808802	+	DDB_G0268644	DDB_G0268644	contains a predicted signal peptide and 3 putative transmembrane domains
chr1	1809151	1815492	-	DDB_G0268616	cepJ	involved in centrosome duplication
chr1	1816266	1816778	-	DDB_G0269038	atp5D	delta subunit of the central stalk of mitochondrial F1F0 ATP synthase%2C the enzyme complex responsible for ATP synthesis
chr1	1817324	1824212	+	DDB_G0269040	DDB_G0269040	similar to tenascin X
chr1	1824333	1826366	-	DDB_G0269042	DDB_G0269042_ps	putative pseudogene%3B similar to a family of FNIP repeat-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0277387%22%3EDDB_G0277387%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272823%22%3EDDB_G0272823%3C%2Fa%3E
chr1	1826960	1827855	-	DDB_G0268646	DDB_G0268646	NA
chr1	1828316	1831796	-	DDB_G0268920	mef2A	involved in cell differentiation during development
chr1	1834587	1838131	-	DDB_G0268638	dstB	NA
chr1	1841483	1844500	+	DDB_G0268650	DDB_G0268650	NA
chr1	1844690	1845832	+	DDB_G0268652	ippB	very similar to %3Ci%3EA. thaliana%3C%2Fi%3E AHL and SAL1 phosphatases and %3Ci%3ES. pombe%3C%2Fi%3E tol1 (halotolerance protein)%2C all related to the %3Ci%3ES. cerevisiae%3C%2Fi%3E HAL2%3B these proteins are 3%27-phosphoadenosine-5%27-phosphate (PAP) phosphatases that also act as inositol polyphosphate 1-phosphatases.
chr1	1846133	1850294	-	DDB_G0268922	DDB_G0268922	NA
chr1	1851313	1852544	-	DDB_G0269044	DDB_G0269044	NA
chr1	1853006	1856574	-	DDB_G0269046	DDB_G0269046	catalyzes the reaction NADPH %2B NAD%2B %3C%3D%3E NADP%2B %2B NADH
chr1	1858322	1860328	-	DDB_G0269048	DDB_G0269048	NA
chr1	1861999	1863226	+	DDB_G0269050	DDB_G0269050	NA
chr1	1863435	1863506	+	DDB_G0294693	tRNA-Thr-AGU-5	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1863917	1865086	-	DDB_G0268656	DDB_G0268656	highly similar to human ULK (Unc51-like kinase)%3B does not contain the full consensus sequence required for kinase function
chr1	1866297	1871670	-	DDB_G0268924	DDB_G0268924	NA
chr1	1872318	1872739	-	DDB_G0268926	DDB_G0268926_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0268660%22%3EDDB_G0268660%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0268662%22%3EDDB_G0268662%3C%2Fa%3E
chr1	1873355	1880413	-	DDB_G0268660	DDB_G0268660	highly similar to neighboring gene%2C  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0268662%22%3E%3Ci%3EDDB_G0268662%3C%2Fi%3E%3C%2Fa%3E%09
chr1	1881042	1888712	-	DDB_G0268662	DDB_G0268662	highly similar to neighboring gene%2C  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0268660%22%3E%3Ci%3EDDB_G0268660%3C%2Fi%3E%3C%2Fa%3E%09
chr1	1889432	1890712	+	DDB_G0268664	aatA	catalyzes the reaction oxaloacetate %2B L-glutamate %3C%3D%3E L-aspartate %2B %26alpha%3B-ketoglutarate%3B likely to be mitochondrial
chr1	1890850	1891251	-	DDB_G0268666	DDB_G0268666	NA
chr1	1891354	1892315	-	DDB_G0268668	cycH	similar to metazoan cyclin H%3B predicted to interact with cyclin-dependent kinase %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285417%22%3E%3Ci%3Ecdk7%3C%2Fi%3E%3C%2Fa%3E to stimulate CTD  (RNA pol II C-Terminal Domain) kinase and CAK (CDK-activating kinase) activities
chr1	1893644	1893808	-	DDB_G0268670	DDB_G0268670	NA
chr1	1895260	1895433	+	DDB_G0268672	DDB_G0268672	NA
chr1	1896312	1896476	-	DDB_G0268674	DDB_G0268674	NA
chr1	1897615	1897791	+	DDB_G0268676	DDB_G0268676	NA
chr1	1898794	1901011	-	DDB_G0269052	DDB_G0269052	NA
chr1	1901921	1904275	+	DDB_G0268678	DDB_G0268678	component of the multisubunit transcription elongation factor NELF%3B human TH1 interacts with A-Raf
chr1	1904782	1906824	+	DDB_G0268680	DDB_G0268680	contains a predicted signal anchor and 3 putative transmembrane domains
chr1	1909652	1911457	+	DDB_G0268928	DDB_G0268928	NA
chr1	1911597	1915361	-	DDB_G0268930	DDB_G0268930_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0272314%22%3EDDB_G0272314%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0272338%22%3EDDB_G0272338%3C%2Fa%3E
chr1	1915657	1916434	+	DDB_G0268932	DDB_G0268932	NA
chr1	1916625	1919356	+	DDB_G0268684	DDB_G0268684	NA
chr1	1919974	1924218	+	DDB_G0268686	DDB_G0268686	contains one C2 domain%3B one MHD1 (Munc13-homology) domain%2C and one MHD2 domain
chr1	1924769	1924948	-	DDB_G0268688	DDB_G0268688	NA
chr1	1926730	1926909	-	DDB_G0268690	DDB_G0268690	NA
chr1	1928290	1929267	+	DDB_G0268692	DDB_G0268692	NA
chr1	1929940	1931025	+	DDB_G0268694	DDB_G0268694	NA
chr1	1931476	1933597	+	DDB_G0269054	ppwd1	conserved peptidyl-prolyl isomerase and WD repeat-containing protein that might be involved in pre-mRNA processing%3B peptidyl-prolyl cis-trans isomerase (PPIase) accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr1	1935672	1937431	+	DDB_G0268696	DDB_G0268696	NA
chr1	1937906	1938403	+	DDB_G0268934	DDB_G0268934	belongs to a family of short proteins that includes proteins from the NADH-ubiquinone oxidoreductase complex I%3B named LYR after a highly conserved tripeptide motif
chr1	1938533	1940644	-	DDB_G0268698	DDB_G0268698	NA
chr1	1941102	1943114	+	DDB_G0268702	copD	delta subunit of the coatomer complex%3B involved in intracellular protein transport%3B ortholog of human ARCN1 (COPD)
chr1	1943354	1944470	-	DDB_G0268704	DDB_G0268704	NA
chr1	1944951	1949839	+	DDB_G0268706	ints3	ortholog of integrator complex subunit 3%2C component of a multiprotein mediator of small nuclear RNA processing
chr1	1950932	1954075	-	DDB_G0269056	DDB_G0269056_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	1954366	1955700	-	DDB_G0269058	DDB_G0269058_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	1956750	1956822	+	DDB_G0294695	tRNA-Asn-GUU-3	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1957162	1958072	-	DDB_G0268618	pinA	similar to human Pin1
chr1	1958550	1960468	+	DDB_G0269060	DDB_G0269060	NA
chr1	1961102	1961834	+	DDB_G0268938	ube2w	conserved E2 ubiquitin-conjugating protein%2C which catalyzes the covalent attachment of ubiquitin to other proteins
chr1	1963368	1965662	+	DDB_G0268708	DDB_G0268708	NA
chr1	1966394	1969829	+	DDB_G0268710	DDB_G0268710	NA
chr1	1970455	1970527	+	DDB_G0294697	tRNA-Asn-GUU-4	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1970717	1971925	+	DDB_G0268942	DDB_G0268942_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1972671	1975748	+	DDB_G0268944	DDB_G0268944_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1977388	1978925	+	DDB_G0268620	pkbA	AGC group%2F AKT family protein serine%2Fthreonine kinase%3B similar to other metazoan Akt%2FPKB%2C including an N-terminal PH domain%2C homologous kinase and C-terminal regulatory domains%2C and phosphorylation sites required for Akt%2FPKB activation
chr1	1979347	1980121	+	DDB_G0268712	DDB_G0268712	similar to a D. purpureum protein
chr1	1980426	1982521	+	DDB_G0268946	DDB_G0268946	NA
chr1	1982796	1984040	-	DDB_G0268948	DDB_G0268948	contains a SAM (and some other nucleotide) binding motif%3B similar to bacterial and eukaryotic methyltransferases
chr1	1984869	1986587	+	DDB_G0268950	gpt6	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr1	1986771	1988565	-	DDB_G0268714	ctu2	ortholog of S. pombe ctu2 (cytosolic thiouridylase subunit 2)%3B with ctu1%2C required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs
chr1	1988769	1990709	-	DDB_G0269062	DDB_G0269062	conserved eukaryotic protein
chr1	1990918	1991418	+	DDB_G0268716	lsm5	member of heteromeric complexes involved in mRNA splicing (lsm2-8) and mRNA degradation (lsm1-7)
chr1	1991527	1993860	-	DDB_G0268718	ptcE	NA
chr1	1994316	1994923	+	DDB_G0268720	selk	contains a selenocysteine at position 112
chr1	1995560	1995631	+	DDB_G0294699	tRNA-Thr-AGU-6	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1997247	1997318	+	DDB_G0294701	tRNA-Thr-AGU-7	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	1997520	1998667	+	DDB_G0269064	DDB_G0269064_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	1999319	2000836	+	DDB_G0268724	DDB_G0268724_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	2003674	2004237	+	DDB_G0269066	DDB_G0269066	NA
chr1	2004451	2004705	-	DDB_G0268726	DDB_G0268726_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268732%22%3EDDB_G0268732%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0275483%22%3EDDB_G0275483%3C%2Fa%3E
chr1	2006217	2006396	-	DDB_G0268730	DDB_G0268730_ps	putative pseudogene%3B small fragment%3B similar to D. discoideum genes  %3Ca href%3D%22%2Fgene%2FDDB_G0268772%22%3EDDB_G0268772%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0275721%22%3EDDB_G0275721%3C%2Fa%3E
chr1	2007191	2008261	+	DDB_G0269068	DDB_G0269068	NA
chr1	2008794	2009048	+	DDB_G0268732	DDB_G0268732	NA
chr1	2009231	2009689	-	DDB_G0268734	DDB_G0268734	NA
chr1	2011975	2014906	-	DDB_G0268958	DDB_G0268958_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr1	2015222	2015446	+	DDB_G0268960	DDB_G0268960	NA
chr1	2016593	2016733	+	DDB_G0269070	DDB_G0269070	conserved hypothetical Dictyostelium protein%3Bidentical to %3Ca href%3D%22%2Fgene%2FDDB_G0277595%22%3EDDB_G0277595%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0294605%22%3EDDB_G0294605%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274459%22%3EDDB_G0274459%3C%2Fa%3E
chr1	2017135	2017584	-	DDB_G0268962	DDB_G0268962	NA
chr1	2017892	2018374	+	DDB_G0269072	DDB_G0269072	NA
chr1	2018396	2018811	+	DDB_G0269074	DDB_G0269074	NA
chr1	2019408	2019643	+	DDB_G0268738	DDB_G0268738	NA
chr1	2022160	2023290	-	DDB_G0269076	DDB_G0269076_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2023312	2023385	+	DDB_G0294703	tRNA-Arg-ACG-1	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2023544	2024644	-	DDB_G0269078	DDB_G0269078	NA
chr1	2026277	2027584	-	DDB_G0268964	lip3	similar to the human lipase family%3B catalyzes the reaction: Triacylglycerol %2B H%3Csub%3E2%3C%2Fsub%3EO %3D diacylglycerol %2B a carboxylate
chr1	2028102	2029414	-	DDB_G0268740	lip2	similar to the human lipase family%3B catalyzes the reaction: Triacylglycerol %2B H%3Csub%3E2%3C%2Fsub%3EO %3D diacylglycerol %2B a carboxylate
chr1	2030028	2031344	-	DDB_G0268742	DDB_G0268742	NA
chr1	2031686	2032762	+	DDB_G0268744	act23	partial actin: amino terminus truncated by 15 amino acid compared to human beta-actin (SwissProt P60709)
chr1	2032965	2034502	-	DDB_G0268746	DDB_G0268746	contains a UBX domain%2C found in ubiquitin-regulatory proteins
chr1	2035070	2036491	-	DDB_G0268748	DDB_G0268748	NA
chr1	2039946	2040221	+	DDB_G0268750	DDB_G0268750	NA
chr1	2040402	2040671	-	DDB_G0268752	DDB_G0268752	NA
chr1	2042126	2043871	+	DDB_G0268966	lip1	similar to the human lipase family%3B catalyzes the reaction: Triacylglycerol %2B H%3Csub%3E2%3C%2Fsub%3EO %3D diacylglycerol %2B a carboxylate
chr1	2044869	2046922	+	DDB_G0268754	DDB_G0268754	catalyzes the hydrolysis of the terminal 1%2C2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2%3B some members of this family are responsible for protein N-linked glycosylation%2C while other participate in the degradation of misfolded glycoproteins in the endoplasmic reticulum
chr1	2047241	2047809	+	DDB_G0268968	DDB_G0268968	NA
chr1	2048275	2048646	+	DDB_G0268756	DDB_G0268756	NA
chr1	2048942	2050448	+	DDB_G0268758	ola1	belongs to the RAS-like GTPase superfamily%3B ortholog of human OLA1
chr1	2050767	2051719	+	DDB_G0268970	DDB_G0268970	homolog of A. thaliana CPI1 (cycloeucalenol cycloisomerase)%3B contains 6 putative transmembrane domains%3B converts pentacyclic cyclopropyl sterols to tetracyclic sterols
chr1	2052354	2052722	-	DDB_G0268974	DDB_G0268974	NA
chr1	2054001	2054913	+	DDB_G0268760	rabQ	NA
chr1	2055281	2056126	-	DDB_G0268762	DDB_G0268762	NA
chr1	2056699	2061951	+	DDB_G0268764	DDB_G0268764	NA
chr1	2063551	2064192	-	DDB_G0268978	DDB_G0268978_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	2064611	2064684	-	DDB_G0294813	tRNA-Val-AAC-6	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2065538	2065780	-	DDB_G0268980	DDB_G0268980_ps	putative pseudogene%3B fragment very similar to parts of DDB_G0268948%2C a putative SAM dependent methyltransferase
chr1	2066042	2067379	-	DDB_G0268982	DDB_G0268982	NA
chr1	2068280	2068627	-	DDB_G0268772	DDB_G0268772	NA
chr1	2069168	2069746	+	DDB_G0268984	DDB_G0268984	NA
chr1	2069754	2070466	+	DDB_G0269080	DDB_G0269080	NA
chr1	2071718	2073633	-	DDB_G0268986	DDB_G0268986_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	2073265	2073338	-	DDB_G0294811	tRNA-Val-UAC-1	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2073845	2075041	-	DDB_G0268774	DDB_G0268774	NA
chr1	2075252	2076868	+	DDB_G0268776	gatB	catalyzes the reaction ATP %2B L-glutamyl-tRNA(Gln) %2B L-glutamine %3D ADP %2B phosphate %2B L-glutaminyl-tRNA(Gln) %2B L-glutamate
chr1	2077109	2078704	-	DDB_G0268988	DDB_G0268988	contains two RNA recognition motif domains (RRMs)%3B conserved in all Dictyostelids
chr1	2079025	2080332	+	DDB_G0268990	DDB_G0268990	NA
chr1	2080758	2081980	+	DDB_G0268992	anapc10	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr1	2082803	2086499	+	DDB_G0268778	rbbB	similar to H. sapiens Retinoblastoma binding proteins RBBP2
chr1	2086586	2087328	-	DDB_G0269082	DDB_G0269082	similar to D. purpureum protein%3B there is a similar second gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274539%22%3E%3Ci%3EDDB_G0274539%3C%2Fi%3E%3C%2Fa%3E
chr1	2087968	2090355	+	DDB_G0268780	DDB_G0268780_ps	putative pseudogene%3B similar to a large D. discoideum gene family including %3Ca href%3D%22%2Fgene%2FDDB_G0347826%22%3EDDB_G0347826%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271228%22%3EDDB_G0271228%3C%2Fa%3E
chr1	2091187	2093082	+	DDB_G0269084	DDB_G0269084	NA
chr1	2093909	2097333	+	DDB_G0268994	manC	NA
chr1	2097735	2099012	+	DDB_G0268782	DDB_G0268782	NA
chr1	2099322	2099393	-	DDB_G0294809	tRNA-Asp-GUC-7	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	2099470	2099543	-	DDB_G0294807	tRNA-Val-AAC-5	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2099731	2102093	-	DDB_G0268996	DDB_G0268996	NA
chr1	2104624	2106869	-	DDB_G0268784	DDB_G0268784	NA
chr1	2108112	2110076	-	DDB_G0268786	DDB_G0268786	NA
chr1	2111460	2112649	-	DDB_G0269000	DDB_G0269000	shares a short region of similarity with INO80C
chr1	2113025	2116145	-	DDB_G0269086	DDB_G0269086	contains an N-terminal alpha%2Fbeta hydrolase fold-1%2C which is also similar to bacterial lysophospholipases
chr1	2116939	2118255	+	DDB_G0268788	DDB_G0268788	NA
chr1	2118381	2119262	-	DDB_G0268790	DDB_G0268790	belongs to the synaptotagmin family%3B contains a predicted signal sequence and a transmembrane domain
chr1	2120474	2122457	-	DDB_G0268792	gtaF	has 18 amino acids between the two CX2C motifs
chr1	2123318	2124574	+	DDB_G0268794	bub2	putative ortholog of S. cerevisiae BUB2%2C a mitotic checkpoint protein
chr1	2124707	2125744	-	DDB_G0268796	DDB_G0268796	NA
chr1	2125974	2127217	+	DDB_G0268798	DDB_G0268798	NA
chr1	2127909	2128811	+	DDB_G0268800	DDB_G0268800	NA
chr1	2129299	2130540	+	DDB_G0268802	gpaJ	NA
chr1	2130761	2132526	-	DDB_G0268634	pde3	NA
chr1	2134088	2134666	-	DDB_G0269088	DDB_G0269088	NA
chr1	2137156	2139957	+	DDB_G0268632	abpA	actin binding protein A also called alpha actinin%2C an actin bundling protein that crosslinks actin into lateral arrays and increases the actin-stimulated Mg ATPase of myosin
chr1	2140091	2141564	+	DDB_G0268806	DDB_G0268806_ps	putative pseudogene%3B highly similar%2C especially a short 5%27 stretch and a longer 3%27 stretch%2C to %3Ca href%3D%22%2Fgene%2FDDB_G0268632%22%3E abpA%3C%2Fa%3E%3B in the center%2C on the opposite strand%2C similar to parts of %3Ca href%3D%22%2Fgene%2FDDB_G0288363%22%3E DDB_G0288363%3C%2Fa%3E
chr1	2141889	2145041	-	DDB_G0268808	DDB_G0268808	NA
chr1	2146485	2149458	+	DDB_G0268810	DDB_G0268810	ortholog of bacterial Mg%3Csup%3E2%2B%3C%2Fsup%3E transporter mgtA%3B contains eight transmembrane domains
chr1	2150422	2154061	+	DDB_G0269004	DDB_G0269004	NA
chr1	2154156	2155464	-	DDB_G0268812	DDB_G0268812	NA
chr1	2157480	2160359	+	DDB_G0268814	DDB_G0268814	NA
chr1	2160760	2161866	-	DDB_G0268816	DDB_G0268816	NA
chr1	2162449	2164638	-	DDB_G0269090	DDB_G0269090	NA
chr1	2164854	2164925	-	DDB_G0294805	tRNA-Met-CAU-4	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2166447	2166518	+	DDB_G0294705	tRNA-Met-CAU-3	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2167055	2168395	+	DDB_G0268818	DDB_G0268818	NA
chr1	2170094	2173749	-	DDB_G0269006	DDB_G0269006	similar to human RNA binding motif proteins 5 and 10 (RBM5 and RBM10)
chr1	2174037	2176085	+	DDB_G0268820	DDB_G0268820	NA
chr1	2179084	2182266	+	DDB_G0268822	DDB_G0268822	NA
chr1	2182743	2184185	-	DDB_G0268824	DDB_G0268824	NA
chr1	2184410	2187469	-	DDB_G0268826	DDB_G0268826	NA
chr1	2190252	2190808	-	DDB_G0269008	DDB_G0269008	contains a predicted signal peptide%3B highly similar to neighboring genes %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268828%22%3E%3Ci%3EDDB_G0268828%3C%2Fi%3E%3C%2Fa%3E
chr1	2191612	2192201	-	DDB_G0268828	DDB_G0268828	contains a predicted signal peptide%3B highly similar to neighboring genes %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269008%22%3E%3Ci%3EDDB_G0269008%3C%2Fi%3E%3C%2Fa%3E
chr1	2192652	2193204	-	DDB_G0269092	DDB_G0269092	contains a predicted signal peptide%3B highly similar to neighboring genes %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268828%22%3E%3Ci%3EDDB_G0268828%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269008%22%3E%3Ci%3EDDB_G0269008%3C%2Fi%3E%3C%2Fa%3E and to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293262%22%3E%3Ci%3EDDB_G0293262%3C%2Fi%3E%3C%2Fa%3E
chr1	2194306	2194536	+	DDB_G0268830	DDB_G0268830	NA
chr1	2194685	2195137	-	DDB_G0268832	DDB_G0268832	NA
chr1	2195578	2196135	+	DDB_G0269010	DDB_G0269010	NA
chr1	2196293	2196562	+	DDB_G0269012	DDB_G0269012	NA
chr1	2196631	2196777	+	DDB_G0268834	DDB_G0268834	NA
chr1	2197263	2197601	-	DDB_G0268836	DDB_G0268836	NA
chr1	2198420	2198887	+	DDB_G0268838	DDB_G0268838	NA
chr1	2199646	2204240	+	DDB_G0268636	roco11	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains LRR%2C Roc%2C COR%2C and protein kinase domains
chr1	2204411	2213336	-	DDB_G0269014	DDB_G0269014	contains a predicted signal sequence and one putative transmembrane domain%3B similar to D. purpureum protein
chr1	2213969	2215930	-	DDB_G0269034	udkA	catalyzes the reaction ATP %2B uridine %3C%3D%3E ADP %2B UMP
chr1	2216150	2216921	+	DDB_G0268840	atg10	Dictyostelium homolog of yeast atg10
chr1	2217041	2218013	-	DDB_G0268630	spsA	NA
chr1	2218538	2218843	+	DDB_G0268842	DDB_G0268842	NA
chr1	2219371	2220365	+	DDB_G0268628	pykA	phosphorylates pyridoxal to pyridoxal 5%27-phosphate%3B member of the TKL (tyrosine kinase-like) group of protein kinases%3B belongs to the MLK protein kinase family
chr1	2221088	2222833	+	DDB_G0268844	DDB_G0268844	NA
chr1	2223009	2224754	+	DDB_G0268846	DDB_G0268846	NA
chr1	2225484	2234074	+	DDB_G0268848	DDB_G0268848	similar%2C though smaller than %3Ci%3EH. sapiens%3C%2Fi%3E SACS%2C a very large protein. The SACS defect causes autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)%2C a neurodegenerative disease%3B %3Ci%3ED. discoideum%3C%2Fi%3E contains three nearly identical genes located next to each other%3B contains two putative ATP binding domains.
chr1	2235139	2243566	+	DDB_G0268850	DDB_G0268850	similar%2C though smaller than %3Ci%3EH. sapiens%3C%2Fi%3E SACS%2C a very large protein. The SACS defect causes autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)%2C a neurodegenerative disease%3B %3Ci%3ED. discoideum%3C%2Fi%3E contains three nearly identical genes located next to each other%3B contains two putative ATP binding domains.
chr1	2244141	2252535	+	DDB_G0268852	DDB_G0268852	similar%2C though smaller than %3Ci%3EH. sapiens%3C%2Fi%3E SACS%2C a very large protein. The SACS defect causes autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)%2C a neurodegenerative disease%3B %3Ci%3ED. discoideum%3C%2Fi%3E contains three nearly identical genes located next to each other%3B contains two putative ATP binding domains.
chr1	2252863	2254749	-	DDB_G0268854	gnt4	CAZy family GT13%3B catalyzes the reaction UDP-N-acetyl-D-glucosamine %2B 3-(a-D-mannosyl)-b-D-mannosyl-R %3C%3D%3E UDP %2B 3-(2-[N-acetyl-b-D-glucosaminyl]-a-D-mannosyl)-b-D-mannosyl-R
chr1	2256023	2257759	+	DDB_G0269016	cyp524A1	NA
chr1	2258756	2260867	+	DDB_G0269018	DDB_G0269018	NA
chr1	2261646	2263586	+	DDB_G0268856	DDB_G0268856	NA
chr1	2264502	2265089	-	DDB_G0268858	DDB_G0268858	contains a predicted signal peptide
chr1	2265532	2265603	-	DDB_G0294803	tRNA-Asp-GUC-6	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	2266964	2269912	+	DDB_G0268860	rngB	NA
chr1	2271073	2273030	-	DDB_G0268862	DDB_G0268862	contains 10 putative transmembrane domains
chr1	2274361	2275842	-	DDB_G0269020	DDB_G0269020	NA
chr1	2276260	2277646	-	DDB_G0268864	DDB_G0268864	NA
chr1	2278096	2278167	+	DDB_G0294707	tRNA-Asp-GUC-1	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	2278922	2281414	+	DDB_G0268866	DDB_G0268866	NA
chr1	2281503	2284779	-	DDB_G0268868	nat10	highly conserved protein%3B ortholog of human NAT10 and yeast KRE33 predicted to localize to the nucleolus
chr1	2286518	2287261	+	DDB_G0268870	DDB_G0268870	NA
chr1	2287976	2294601	+	DDB_G0268872	DDB_G0268872	similar to members of the ubiquitin specific peptidase (USP) family%2C including USP44 and USP3
chr1	2295154	2296270	+	DDB_G0269022	DDB_G0269022	NA
chr1	2296806	2297615	+	DDB_G0268874	DDB_G0268874	NA
chr1	2297918	2302573	-	DDB_G0268876	DDB_G0268876	member of the TKL (tyrosine kinase-like) group of protein kinases%3B contains filamin repeat similar to ABP120
chr1	2304383	2305729	+	DDB_G0268878	DDB_G0268878	NA
chr1	2306169	2308216	-	DDB_G0268880	atxn10	similar to the human ataxin-10 (ATXN10)%3B defects in the gene cause spinocerebellar ataxia 10 (SCA10)%3B contains an armadillo-like helical domain (ARM-like)
chr1	2308576	2308977	-	DDB_G0268882	DDB_G0268882	NA
chr1	2309454	2310009	+	DDB_G0268884	DDB_G0268884	ortholog of E. coli OsmC%2C a stress-inducible protein%3B there is another member of this family in Dictyostelium%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269418%22%3E%3Ci%3EDDB_G0269418%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E 
chr1	2311232	2323957	+	DDB_G0268886	vps13E	weakly similar to S. cerevisiae VPS13%2C involved in vacuolar protein sorting and protein-Golgi retention
chr1	2324197	2330890	-	DDB_G0268888	zizD	NA
chr1	2331887	2332531	-	DDB_G0268890	aplJ	NA
chr1	2333199	2335088	+	DDB_G0269024	ate1	ortholog of the conserved arginine-tRNA-protein transferase%2C ATE1%3B involved in the post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the ubiquitin pathway%3B catalyzes rhe reaction L-arginyl-tRNA %2B protein %3D tRNA %2B L-arginyl-protein
chr1	2336357	2337109	+	DDB_G0268892	DDB_G0268892	contains a predicted signal peptide
chr1	2337236	2339585	-	DDB_G0269026	abcG23	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr1	2339948	2340211	-	DDB_G0268894	DDB_G0268894	NA
chr1	2340589	2340909	-	DDB_G0268896	DDB_G0268896	NA
chr1	2341344	2344486	-	DDB_G0268898	wdr75	ortholog of H. sapiens WDR75 and S. cerevisiae NAN1
chr1	2344800	2345556	-	DDB_G0268900	DDB_G0268900	NA
chr1	2346148	2348910	+	DDB_G0268902	DDB_G0268902	NA
chr1	2353413	2355776	+	DDB_G0268904	DDB_G0268904	NA
chr1	2356141	2356699	+	DDB_G0268906	DDB_G0268906	NA
chr1	2357127	2361800	+	DDB_G0268626	DDB_G0268626	%3Ci%3EDictyostelium%3C%2Fi%3E family protein
chr1	2362108	2363237	+	DDB_G0268624	DDB_G0268624	NA
chr1	2363310	2363892	-	DDB_G0268908	racK_ps	putative pseudogene%3B rac family gene
chr1	2364212	2365034	-	DDB_G0268622	rac1B	enriched in gametes
chr1	2365532	2366200	+	DDB_G0268910	rabT1	NA
chr1	2366931	2367002	+	DDB_G0294709	tRNA-Glu-UUC-2	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	2367538	2367990	-	DDB_G0269028	DDB_G0269028	NA
chr1	2368298	2368369	-	DDB_G0294801	tRNA-Glu-UUC-6	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	2369649	2369921	-	DDB_G0269030	DDB_G0269030_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	2370125	2370197	-	DDB_G0294799	tRNA-Gln-UUG-5	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2371018	2371090	+	DDB_G0294711	tRNA-Gln-UUG-2	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2371552	2385174	-	DDB_G0268914	DDB_G0268914	NA
chr1	2385345	2389186	-	DDB_G0269032	DDB_G0269032	contains two coiled-coil domains%3B central region predicted to have structural similarity to the beta-sandwich domain of the Sec23%2F24 superfamily 
chr1	2389897	2390193	+	DDB_G0268916	DDB_G0268916	NA
chr1	2390365	2390437	-	DDB_G0294797	tRNA-Asn-GUU-7	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2390879	2392213	+	DDB_G0269094	DDB_G0269094_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2393899	2394756	-	DDB_G0269096	DDB_G0269096	NA
chr1	2395862	2397880	+	DDB_G0306367	DDB_G0306367	similar to %3Ci%3EDictystelium%3C%2Fi%3E cfrA%2C B%2C C%2C and D (GP138A-D)
chr1	2398344	2398416	+	DDB_G0294713	tRNA-Lys-UUU-3	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2398639	2402631	+	DDB_G0306370	DDB_G0306370_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	2402920	2403422	-	DDB_G0270840	DDB_G0270840_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2404459	2407381	+	DDB_G0270458	DDB_G0270458_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	2404737	2404808	+	DDB_G0294715	tRNA-Thr-AGU-8	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2408349	2408934	+	DDB_G0269256	DDB_G0269256	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain%3B identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269270%22%3E%3Ci%3EDDB_G0269270%3C%2Fi%3E%3C%2Fa%3E
chr1	2410260	2410847	-	DDB_G0269258	DDB_G0269258_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	2411033	2411674	-	DDB_G0270460	DDB_G0270460_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	2411874	2411960	-	DDB_G0294795	tRNA-Trp-CCA-3	transfers a tryptophan residue to a growing polypeptide chain during protein synthesis%0A
chr1	2414216	2414296	+	DDB_G0294717	tRNA-Ser-GCU-1	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2415581	2416221	+	DDB_G0269260	DDB_G0269260	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr1	2416810	2417466	+	DDB_G0269262	rabT2	NA
chr1	2419170	2419985	-	DDB_G0269264	DDB_G0269264_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	2420227	2423526	-	DDB_G0269266	DDB_G0269266_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr1	2423664	2424209	-	DDB_G0269268	DDB_G0269268_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr1	2424793	2424873	-	DDB_G0294793	tRNA-Ser-GCU-2	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2425241	2425771	-	DDB_G0270462	DDB_G0270462_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2425838	2427457	+	DDB_G0270464	DDB_G0270464_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2428475	2429089	-	DDB_G0269270	DDB_G0269270	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain%3B identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269256%22%3E%3Ci%3EDDB_G0269256%3C%2Fi%3E%3C%2Fa%3E
chr1	2429715	2431239	-	DDB_G0270466	DDB_G0270466	NA
chr1	2431765	2433276	-	DDB_G0269136	efaAII	elongation factor 1 alpha%2C one of two genes coding for the same protein%3B binds and bundles F-actin
chr1	2434615	2438410	+	DDB_G0269272	DDB_G0269272	NA
chr1	2438501	2440838	-	DDB_G0269274	dhak	catalyzes the reaction ATP %2B glycerone %3D ADP %2B glycerone phosphate
chr1	2442246	2442509	+	DDB_G0269276	DDB_G0269276	NA
chr1	2442606	2443928	-	DDB_G0269278	DDB_G0269278	NA
chr1	2444312	2445271	-	DDB_G0269280	DDB_G0269280	NA
chr1	2445906	2446880	-	DDB_G0269282	DDB_G0269282	NA
chr1	2447181	2448908	-	DDB_G0270468	DDB_G0270468	NA
chr1	2449936	2451468	-	DDB_G0269284	DDB_G0269284	similar to D. purpureum protein
chr1	2451692	2455913	-	DDB_G0269286	DDB_G0269286	NA
chr1	2456628	2467773	-	DDB_G0269288	DDB_G0269288	NA
chr1	2468482	2469686	+	DDB_G0269290	nap1	NAP proteins act as histone chaperones%2C shuttling both core and linker histones from their site of synthesis in the cytoplasm to the nucleus
chr1	2470067	2471311	+	DDB_G0269292	sugt1	ortholog of S. cerevisiae SGT1 and mammalian SUGT1%2C associated with the SCF (Skp1p%2FCdc53p%2FF box protein) ubiquitin ligase complex
chr1	2471481	2474033	-	DDB_G0269294	DDB_G0269294	NA
chr1	2474747	2476080	+	DDB_G0269296	DDB_G0269296	NA
chr1	2476607	2480100	-	DDB_G0269298	gefX	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family%3B contains RasGEF nucleotide exchange factor domain
chr1	2481510	2482781	+	DDB_G0269300	DDB_G0269300	has similarity to human CD2BP2%2C a CD2 antigen cytoplasmic tail-binding protein and yeast LIN1%2C a non-essential component of the U5 snRNP
chr1	2482897	2483850	-	DDB_G0269302	DDB_G0269302	NA
chr1	2484101	2485936	+	DDB_G0269304	DDB_G0269304	similar to S. cerevisiae SHQ1%2C which is required for box H%2FACA small nucleolar ribonucleoprotein particle biogenesis%3B contains one CS domain
chr1	2485989	2488139	-	DDB_G0269306	dhx35	DEAD%2FDEAH box helicases are involved in various aspects of RNA metabolism
chr1	2488609	2490162	-	DDB_G0270470	DDB_G0270470	similar to D. purpureum protein
chr1	2491060	2493733	+	DDB_G0269308	DDB_G0269308_ps	member of a Dictyostelium protein family that includes DG1041
chr1	2493841	2496701	-	DDB_G0270472	DDB_G0270472	NA
chr1	2497222	2499823	-	DDB_G0269312	DDB_G0269312	ortholog of S. cerevisiae ESF1%2C a nucleolar protein involved in pre-rRNA processing
chr1	2500071	2500579	-	DDB_G0270474	DDB_G0270474	NA
chr1	2501983	2503317	-	DDB_G0270842	DDB_G0270842_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2503577	2503649	+	DDB_G0294719	tRNA-Lys-UUU-4	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2504768	2505723	-	DDB_G0270476	DDB_G0270476_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0270958%22%3EDDB_G0270958%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270850%22%3EDDB_G0270850%3C%2Fa%3E
chr1	2506114	2516856	+	DDB_G0295757	DDB_G0295757	NA
chr1	2517195	2519734	-	DDB_G0270848	DDB_G0270848_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0270958%22%3EDDB_G0270958%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270644%22%3EDDB_G0270644%3C%2Fa%3E
chr1	2519831	2525629	+	DDB_G0270478	DDB_G0270478_ps	putative pseudogene%3B IPT%2FTIG family protein
chr1	2525862	2528497	-	DDB_G0270850	DDB_G0270850	NA
chr1	2529046	2539393	+	DDB_G0270480	DDB_G0270480	NA
chr1	2540112	2540788	-	DDB_G0269318	DDB_G0269318	NA
chr1	2541259	2541679	-	DDB_G0269320	DDB_G0269320_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0292008%22%3EDDB_G0292008%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283487%22%3EDDB_G0283487%3C%2Fa%3E
chr1	2542013	2542876	-	DDB_G0269322	DDB_G0269322	NA
chr1	2543534	2544345	-	DDB_G0269324	gins4	subunit 4 of the conserved replication complex GINS%2C which is essential for initiation of DNA replication in X. laevis
chr1	2544681	2547056	-	DDB_G0269326	zntD	ZIP family zinc transporter%2C LZT subfamily member%3B contains 8 transmembrane domains%3B expressed in pstAB cells
chr1	2548313	2551945	+	DDB_G0269328	DDB_G0269328	NA
chr1	2552986	2554021	+	DDB_G0269330	DDB_G0269330	NA
chr1	2554441	2556496	+	DDB_G0269332	DDB_G0269332	belongs to a family of zinc transporters that are integral membrane proteins%2C which are found to increase tolerance to divalent metal ions%3B contains 6 putative transmembrane domains
chr1	2556676	2557732	-	DDB_G0269334	DDB_G0269334	contains a C-terminal C2 domain and an N-terminal XYPPX repeat
chr1	2558667	2558748	+	DDB_G0294721	tRNA-Ser-AGA-1	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2559165	2560492	+	DDB_G0270852	DDB_G0270852_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	2560506	2560578	-	DDB_G0294791	tRNA-Lys-CUU-3	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2560862	2561113	+	DDB_G0269336	DDB_G0269336	NA
chr1	2561561	2563899	+	DDB_G0270482	gfm1	involved in the translocation of the nascent peptide from the ribosomal A-site to the P-site
chr1	2564023	2565400	-	DDB_G0269338	bzpE	NA
chr1	2565964	2566797	+	DDB_G0269340	DDB_G0269340	NA
chr1	2567416	2567916	+	DDB_G0269342	DDB_G0269342	NA
chr1	2568156	2569534	-	DDB_G0269344	DDB_G0269344	ortholog of the H. sapiens angio-associated migratory cell protein AAMP
chr1	2569786	2570613	+	DDB_G0269346	DDB_G0269346	NA
chr1	2570683	2572593	-	DDB_G0269348	DDB_G0269348	NA
chr1	2573853	2575961	-	DDB_G0269350	DDB_G0269350	NA
chr1	2576335	2577600	-	DDB_G0269352	mcfD	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr1	2578522	2581449	+	DDB_G0269354	DDB_G0269354	conserved hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E protein%2C contains one EGF-like%2C type 3 domain
chr1	2581654	2582858	-	DDB_G0270854	nif3	ortholog of human NIF3L1%3B belongs to the UPF0135 (NIF3) family
chr1	2583576	2584480	+	DDB_G0269356	DDB_G0269356	NA
chr1	2584566	2585608	-	DDB_G0269358	DDB_G0269358	NA
chr1	2585971	2587983	-	DDB_G0269360	DDB_G0269360	NA
chr1	2591243	2593999	+	DDB_G0270856	DDB_G0270856	NA
chr1	2594752	2606541	+	DDB_G0270488	DDB_G0270488	NA
chr1	2607006	2607609	+	DDB_G0270490	DDB_G0270490	NA
chr1	2607973	2609167	+	DDB_G0270492	DDB_G0270492	NA
chr1	2609297	2610806	-	DDB_G0269362	frmB	Band 4.1 contains the FERM domain%3B found in a number of cytoskeletal-associated proteins and involved in the linkage of cytoplasmic proteins to the membrane
chr1	2611408	2612236	-	DDB_G0270494	DDB_G0270494	NA
chr1	2612482	2622117	-	DDB_G0269364	stlA	belongs to the beta-ketoacyl synthase family%3B type III polyketide synthase%3B catalyzes iterative polyketide extension%3B from hexanoyl-CoA%2C can catalyze three polyketide chain extensions followed by aldol cyclization to synthesize demethyl-4-methyl-5-pentylbenzene-1%2C3-diol (MPBD)%3B starter unit can vary from acyl CoA substrates ranging from 3-20 carbons %3Cbr%2F%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse the stlA gene encoding a polyketide synthase with the stlA locus associated with deficient stalk formation (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Freference%2Freference.pl?refNo%3D4308%22%3E Morrissey and Loomis 1981%3C%2Fa%3E) 
chr1	2627248	2628493	+	DDB_G0269236	rab7A	rab family small GTPase involved in vesicle fusion during endocytosis%3B there is another rab7 homolog%2C %3Ci%3Erab7B%3C%2Fi%3E
chr1	2629488	2630345	+	DDB_G0269368	DDB_G0269368	similar to human SYS1 which is involved in protein trafficking%3B contains 4 putative transmembrane domains
chr1	2630812	2631796	+	DDB_G0269370	DDB_G0269370	very similar to the human 25 kDa cleavage and polyadenylation specificity factor%2C component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3%27 processing
chr1	2632261	2632988	+	DDB_G0269372	DDB_G0269372	NA
chr1	2633520	2636041	-	DDB_G0269374	DDB_G0269374	NA
chr1	2636802	2638688	+	DDB_G0270496	DDB_G0270496	putative ortholog of H. sapiens AATF%2C apoptosis-antagonizing transcription factor%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0270496 shows extensive similarities with the %22apoptosis antagonizing transcription factor%22 AATF%2C which is widely conserved in animals. Under the alternate name Che-1%2C the gene product has been described as a RNA polymerase II cofactor which associates with the promoters of E2F-activated genes and promotes their transcription under normal conditions. After DNA damage by doxorubicin or ionizing radiation%2C AATF%2FChe-1 is phosphorylated by ATM and Chk2%2C which causes it to dissociate from these promoters and re-associate with those of p53-target genes%2C as well as p53 itself (see Floridi and Fanciulli%2C Cell Cycle 6%2C 804-806 (2007). AATF%2FChe1 has also been reported to associate with Rb%2C and to block the Rb-mediated repression of these promoters by HDAC (Fanciulli et al%2C FASEB Journal 14%2C 904-912 (2000).%3Cbr%3E DDB_G0270496 is threefold (p%3C0.004) overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). Most of the classic E2F target genes are overexpressed in this strain%2C and it seems possible that AATF%2FChe1 upregulation contributes to this effect. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E
chr1	2640023	2641648	+	DDB_G0269146	ifdA	similar to eukaryotic translation initiation factor 4A%2C isoform 2 
chr1	2642577	2643428	-	DDB_G0269376	DDB_G0269376	NA
chr1	2644089	2645514	+	DDB_G0269378	rad1	similar to Rad1%2C a component of a heterotrimeric clamp (the 9-1-1 complex) that recognizes damaged DNA and initiates signal transduction for repair
chr1	2645714	2650717	-	DDB_G0269380	DDB_G0269380	P-type ATPase (E1-E2)%3B highly similar to human ATP8A1 believed to be involved in the transport of aminophospholipids
chr1	2653185	2654791	-	DDB_G0269382	pepD	NA
chr1	2655370	2657301	+	DDB_G0269384	DDB_G0269384	NA
chr1	2657392	2667176	-	DDB_G0269250	pats1	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains LRR%2C Roc%2C COR%2C WD40%2C and protein kinase domains
chr1	2668447	2670641	-	DDB_G0269386	grlK	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr1	2676041	2677561	+	DDB_G0270858	DDB_G0270858	NA
chr1	2678066	2680954	+	DDB_G0269388	corB	ortholog of human coronin-7 (CORO7)%3B long protein corresponding to two coronin equivalents%3B regulates F-actin depolymerization and is thus involved in substrate adhesion%2C phagocytosis and cell motility
chr1	2681142	2681466	-	DDB_G0269390	DDB_G0269390	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon
chr1	2682747	2684635	-	DDB_G0270500	d2hgdh	mitochondrial enzyme%2C catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate%3B ortholog of the H. sapiens D2HGDH%2C which when defect causes  D-2-hydroxyglutaric aciduria%2C a rare recessive neurometabolic disorder
chr1	2685505	2686101	-	DDB_G0270502	DDB_G0270502_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2686145	2686834	-	DDB_G0270504	DDB_G0270504_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2687279	2687350	+	DDB_G0294723	tRNA-Glu-UUC-3	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	2687898	2689235	-	DDB_G0270506	DDB_G0270506	NA
chr1	2689530	2690085	-	DDB_G0269392	DDB_G0269392	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr1	2691885	2695028	-	DDB_G0270860	DDB_G0270860_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2695319	2696653	-	DDB_G0270862	DDB_G0270862_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2697090	2697162	+	DDB_G0294725	tRNA-Lys-CUU-2	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2698672	2698743	-	DDB_G0294789	tRNA-Glu-UUC-5	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	2699017	2700122	+	DDB_G0269394	mcfE	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr1	2700289	2705516	-	DDB_G0269204	dhkE	NA
chr1	2708681	2709448	-	DDB_G0269398	DDB_G0269398	NA
chr1	2710210	2711100	+	DDB_G0269400	DDB_G0269400	similar to D. purpureum protein
chr1	2711495	2713021	-	DDB_G0269402	DDB_G0269402	the SWIM domain is found in variety of prokaryotic and eukaryotic proteins%3B it is predicted to have DNA-binding and protein-protein interaction functions in different contexts
chr1	2713558	2714296	-	DDB_G0269404	DDB_G0269404	similar to human DUSP19%3B predicted to have dual specificity toward Ser%2FThr and Tyr-containing proteins
chr1	2715190	2716197	-	DDB_G0269406	rad52	similar to the RAD52 DNA repair protein that  is involved in double-stranded break repair
chr1	2716911	2717087	-	DDB_G0269408	DDB_G0269408	NA
chr1	2717192	2717475	-	DDB_G0270508	DDB_G0270508	NA
chr1	2718039	2718873	+	DDB_G0270510	spc2	ortholog of the conserved microsomal signal peptidase 25 kDa subunit%3B the signal peptidase complex is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum%3B contains two putative transmembrane domains
chr1	2719928	2720827	+	DDB_G0269410	DDB_G0269410	catalyzes the reaction L-proline %2B NAD(P)%3Csup%3E%2B%3C%2Fsup%3E %3C%3D%3E 1-pyrroline-5-carboxylate %2B NAD(P)H %2B H%3Csup%3E%2B%3C%2Fsup%3E
chr1	2724169	2725668	+	DDB_G0269412	paf1	component of the conserved Paf1 complex%2C a multifunctional complex%2C involved in histone methylation and plays a role in RNA elongation and processing
chr1	2725897	2726556	-	DDB_G0269414	ebp	similar to mammalian EBP (and EBPL)%3B EBP catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers%3B defects in hEBP cause chondrodysplasia punctata X-linked dominant type 2%2C a rare disorder of defective cholesterol biosynthesis
chr1	2727197	2728127	+	DDB_G0269416	rab32B	similar to H. sapiens rab32 and rab38
chr1	2728317	2728894	-	DDB_G0269418	DDB_G0269418	similar to E. coli OsmC%2C a stress-inducible protein%2C and down-regulated by hyperosmotic shock%3B there is another member of this gene family in Dictyostelium%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268884%22%3E%3Ci%3EDDB_G0268884%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr1	2730080	2730479	+	DDB_G0269420	DDB_G0269420	NA
chr1	2730908	2731372	-	DDB_G0269422	DDB_G0269422	NA
chr1	2731859	2732599	+	DDB_G0270512	DDB_G0270512_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0270090%22%3EDDB_G0270090%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0288013%22%3EDDB_G0288013%3C%2Fa%3E
chr1	2732721	2736502	-	DDB_G0269424	gxcB	NA
chr1	2738058	2740498	+	DDB_G0269426	DDB_G0269426	contains a double-stranded RNA-binding motif in the amino terminus
chr1	2741124	2742151	+	DDB_G0270514	DDB_G0270514_ps	putative pseudogene%3B similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0269428%22%3EDDB_G0269428%3C%2Fa%3E
chr1	2743300	2744337	+	DDB_G0269428	DDB_G0269428	belongs to a gene family conserved in amoeba
chr1	2744495	2747528	-	DDB_G0270864	DDB_G0270864	NA
chr1	2747913	2749221	-	DDB_G0270866	magoh	conserved protein that is part of a post-splicing multiprotein complex involved in mRNA nuclear export%3B the human ortholog interacts with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0286007%22%3E%3Ci%3Erbm8A%3C%2Fi%3E%3C%2Fa%3E
chr1	2750055	2752238	+	DDB_G0347686	DDB_G0347686	NA
chr1	2752444	2753176	-	DDB_G0347687	DDB_G0347687	NA
chr1	2753471	2756444	+	DDB_G0269430	DDB_G0269430	Sel1-like repeats are tetratricopeptide repeat sequences originally identified in a C. elegans receptor molecule which is a key negative regulator of the Notch pathway%3B Dictyostelium%2C like mammals%2C has two sel1-like proteins%2C which are located next to each other
chr1	2756997	2760268	+	DDB_G0269432	DDB_G0269432	Sel1-like repeats are tetratricopeptide repeat sequences originally identified in a C. elegans receptor molecule which is a key negative regulator of the Notch pathway%3B Dictyostelium%2C like mammals%2C has two sel1-like proteins%2C which are located next to each other
chr1	2760643	2760996	-	DDB_G0269434	DDB_G0269434	NA
chr1	2762300	2763013	+	DDB_G0269436	DDB_G0269436	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%2C contains a putative signal sequence
chr1	2764361	2765065	+	DDB_G0270518	DDB_G0270518	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%2C contains a putative signal sequence
chr1	2765942	2767289	+	DDB_G0270520	DDB_G0270520	NA
chr1	2767401	2768924	-	DDB_G0269438	zpr1	ortholog of ZPR1%2C a eukaryotic zinc finger protein 
chr1	2769350	2770838	-	DDB_G0270522	DDB_G0270522	NA
chr1	2771493	2773012	-	DDB_G0270524	DDB_G0270524	NA
chr1	2774064	2776697	-	DDB_G0270868	DDB_G0270868	NA
chr1	2777615	2781943	+	DDB_G0270870	atp9b	P-type ATPase (E1-E2)%3B ortholog of human ATP9B and yeast NEO1%2C which is involved in transport from the Golgi to the ER
chr1	2782084	2784323	-	DDB_G0269440	DDB_G0269440	NA
chr1	2784673	2787444	-	DDB_G0269442	DDB_G0269442	NA
chr1	2788108	2789424	+	DDB_G0269444	hemB	catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen%2C the second step in heme biosynthesis
chr1	2789495	2790655	-	DDB_G0269446	DDB_G0269446	NA
chr1	2791078	2795119	-	DDB_G0269448	DDB_G0269448	NA
chr1	2795744	2797105	-	DDB_G0269134	efaAI	elongation factor 1 alpha%2C one of two genes coding for the same protein%3B binds and bundles F-actin%3B expressed in prespore cells
chr1	2798117	2798819	-	DDB_G0269450	DDB_G0269450	NA
chr1	2799520	2802510	-	DDB_G0269452	DDB_G0269452	NA
chr1	2803384	2804805	-	DDB_G0270528	gpt2	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr1	2805074	2806555	-	DDB_G0294553	DDB_G0294553	NA
chr1	2807320	2808805	-	DDB_G0269454	trpS	catalyzes the reaction ATP %2B L-tryptophan %2B tRNATrp %3C%3D%3E AMP %2B diphosphate %2B L-tryptophan-tRNAThr
chr1	2809230	2809981	-	DDB_G0270530	DDB_G0270530	NA
chr1	2810443	2810655	+	DDB_G0269456	DDB_G0269456	NA
chr1	2811310	2812227	+	DDB_G0269458	ubqJ	NA
chr1	2814532	2815989	-	DDB_G0270532	DDB_G0270532	NA
chr1	2817548	2817634	+	DDB_G0294727	tRNA-Trp-CCA-1	transfers a tryptophan residue to a growing polypeptide chain during protein synthesis%0A
chr1	2818161	2825118	-	DDB_G0269460	DDB_G0269460	NA
chr1	2825931	2833171	+	DDB_G0269462	DDB_G0269462	large protein containing two ubiquitin domains%3B has no ortholog in other organisms
chr1	2833557	2833931	-	DDB_G0269464	DDB_G0269464	NA
chr1	2834458	2835595	+	DDB_G0269466	DDB_G0269466	NA
chr1	2836013	2836591	+	DDB_G0269468	DDB_G0269468	NA
chr1	2836764	2838030	-	DDB_G0269470	mcfF	ortholog of H. sapiens SLC25A28 and D. reiro SLC25A37%2C involved in iron transport across the mitochondrial membrane%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr1	2839118	2839714	+	DDB_G0269472	psmB2	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr1	2840597	2843560	+	DDB_G0269474	fcsB	catalyzes the reaction ATP %2B a long-chain carboxylic acid %2B CoA %3D AMP %2B diphosphate %2B an acyl-CoA
chr1	2844541	2845608	+	DDB_G0269476	act31	actin related protein of unknown function
chr1	2845861	2846125	-	DDB_G0269478	DDB_G0269478	NA
chr1	2849081	2849365	-	DDB_G0307769	DDB_G0307769_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2849483	2849972	-	DDB_G0307754	DDB_G0307754_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2850044	2850116	+	DDB_G0294729	tRNA-Gln-UUG-3	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2850392	2851120	+	DDB_G0270872	DDB_G0270872_ps	putative pseudogene%2C similar to the conserved hypothetical Dictyostelium protein that contains a weak von Willebrand factor%2C type A domain
chr1	2851126	2851466	-	DDB_G0269480	DDB_G0269480_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0292092%22%3EDDB_G0292092%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269958%22%3EDDB_G0269958%3C%2Fa%3E
chr1	2852550	2854865	+	DDB_G0269482	DDB_G0269482	conserved hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E protein%3B contains a weak von Willebrand factor%2C type A domain
chr1	2855252	2855324	-	DDB_G0294787	tRNA-Gln-UUG-4	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2855765	2857099	+	DDB_G0270536	DDB_G0270536_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	2859071	2859931	+	DDB_G0269484	DDB_G0269484	NA
chr1	2860257	2863558	+	DDB_G0269486	DDB_G0269486	NA
chr1	2863702	2864193	-	DDB_G0269488	DDB_G0269488	NA
chr1	2864584	2866468	-	DDB_G0269160	nxnA	calcium-regulated phospholipid- and membrane-binding protein
chr1	2869010	2869331	-	DDB_G0269492	DDB_G0269492_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0288393%22%3EDDB_G0288393%3C%2Fa%3E
chr1	2869907	2872362	-	DDB_G0270538	DDB_G0270538	NA
chr1	2873819	2874859	+	DDB_G0270540	DDB_G0270540	NA
chr1	2875151	2876971	-	DDB_G0269494	DDB_G0269494	NA
chr1	2877753	2877825	+	DDB_G0294731	tRNA-Lys-UUU-5	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2878932	2882063	-	DDB_G0269496	gacZ	NA
chr1	2883107	2884312	-	DDB_G0269498	DDB_G0269498	NA
chr1	2884549	2886392	-	DDB_G0295761	nle1	NA
chr1	2887577	2888427	+	DDB_G0269500	DDB_G0269500	similar to D. purpureum protein%3B contains 5 predicted transmembrane domains
chr1	2888658	2894331	+	DDB_G0269502	nup160	component of the nuclear pore complex%2C which plays a role in RNA export
chr1	2895800	2898550	+	DDB_G0269214	abcG1	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr1	2898939	2899652	-	DDB_G0269504	DDB_G0269504	conserved in Dictyostelids%3B predicted to have structural similarity to the NFT2-like superfamily (nuclear transport factor)%3B there are two highly similar genes%2C %3Ca href%3D%22%2Fgene%2FDDB_G0269506%22%3E%3Ci%3EDDB_G0269506%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269508%22%3E%3Ci%3EDDB_G0269508%3C%2Fi%3E%3C%2Fa%3E%2C downstream
chr1	2900455	2901168	-	DDB_G0269506	DDB_G0269506	conserved in Dictyostelids%3B predicted to have structural similarity to the NFT2-like superfamily (nuclear transport factor)%3B there are two highly similar genes%2C %3Ca href%3D%22%2Fgene%2FDDB_G0269504%22%3E%3Ci%3EDDB_G0269504%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269508%22%3E%3Ci%3EDDB_G0269508%3C%2Fi%3E%3C%2Fa%3E%2C upstream and downstream
chr1	2902023	2902736	-	DDB_G0269508	DDB_G0269508	conserved in Dictyostelids%3B predicted to have structural similarity to the NFT2-like superfamily (nuclear transport factor)%3B there are two highly similar genes%2C %3Ca href%3D%22%2Fgene%2FDDB_G0269506%22%3E%3Ci%3EDDB_G0269506%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269504%22%3E%3Ci%3EDDB_G0269504%3C%2Fi%3E%3C%2Fa%3E%2C upstream
chr1	2903199	2904480	-	DDB_G0269122	cysA	catalyzes the reaction cystathionine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E 2-oxobutanoate %2B L-cysteine %2B NH%3Csub%3E3%3C%2Fsub%3E
chr1	2905172	2906360	-	DDB_G0269510	vps37	putative component of the ESCRT-I complex (endosomal sorting complex required for transport)
chr1	2906854	2908497	+	DDB_G0269232	DDB_G0269232	conserved in D. purpureum and P. pallidum%3B REMI mutant arrests at the finger stage (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0269232%22%3Ecommunity annotation%3C%2Fa%3E) 
chr1	2908706	2909031	-	DDB_G0269512	DDB_G0269512	NA
chr1	2909436	2910548	-	DDB_G0269514	DDB_G0269514	NA
chr1	2911005	2911890	-	DDB_G0269174	rab1C	similar to rab1
chr1	2912518	2912643	-	DDB_G0269516	DDB_G0269516	NA
chr1	2913067	2913153	+	DDB_G0294733	tRNA-Trp-CCA-2	transfers a tryptophan residue to a growing polypeptide chain during protein synthesis%0A
chr1	2913781	2918690	+	DDB_G0270544	gdt6	member of the TKL (tyrosine kinase-like) group and the GDT family%3B unlikely to function as a kinase as it does not contain a catalytic aspartate%3B putative transmembrane protein
chr1	2919137	2921794	+	DDB_G0270548	gdt10_ps	putative pseudogene%3B related to the GDT (growth-development transition) family of protein kinases
chr1	2922116	2925271	-	DDB_G0269126	DDB_G0269126	contains a signal peptide%3B small gene family in D. discoideum%3B D. purpureum has a single gene%3B REMI mutant arrests at the finger stage (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0269126%22%3Ecommunity annotation%3C%2Fa%3E) 
chr1	2926042	2931347	+	DDB_G0270550	gdt4	member of the TKL (tyrosine kinase-like) group and the GDT family%3B putative transmembrane protein
chr1	2931465	2932451	-	DDB_G0270878	DDB_G0270878	NA
chr1	2933712	2938961	-	DDB_G0270880	gflC	contains a plant homeodomain (PHD) finger motif%3B no other sequence similarity exists outside this small domain
chr1	2940068	2941175	-	DDB_G0270882	nosip	NA
chr1	2941556	2941915	-	DDB_G0270884	abnA	very similar to Acanthamoeba actobindin%3B contains two actin-binding WH2 (Wiskott Aldrich syndrome homology region 2) domains
chr1	2942536	2942924	-	DDB_G0269518	abnB	very similar to Acanthamoeba actobindin%3B contains two actin-binding WH2 (Wiskott Aldrich syndrome homology region 2) domains
chr1	2943585	2943988	+	DDB_G0269520	abnC	very similar to Acanthamoeba actobindin%3B contains two actin-binding WH2 (Wiskott Aldrich syndrome homology region 2) domains
chr1	2944304	2945241	-	DDB_G0269522	DDB_G0269522	NA
chr1	2946561	2947922	-	DDB_G0269526	argD	catalyzes the reaction N%3Csub%3E2%3C%2Fsub%3E-acetyl-L-ornithine %2B 2-oxoglutarate %3D N-acetyl-L-glutamate 5-semialdehyde %2B L-glutamate
chr1	2948285	2950264	-	DDB_G0269528	fslD	similar to G-protein-coupled receptors%2Ffrizzled proteins%3B contains 7 putative transmembrane domains and a potential signal sequence
chr1	2951187	2953550	+	DDB_G0270552	DDB_G0270552	contains one C2H2-type zinc finger motif and 2 ankyrin repeats%3B contains 2 predicted coiled-coil domains
chr1	2954280	2954993	+	DDB_G0269530	DDB_G0269530	conserved in Dictyostelium%3B predicted to have structural similarity to the NFT2-like superfamily (nuclear transport factor)
chr1	2955284	2955724	+	DDB_G0269532	DDB_G0269532	NA
chr1	2956743	2957453	+	DDB_G0269534	DDB_G0269534	NA
chr1	2958224	2958937	+	DDB_G0269536	DDB_G0269536	NA
chr1	2959764	2960474	+	DDB_G0269538	DDB_G0269538	NA
chr1	2961358	2962071	+	DDB_G0269540	DDB_G0269540	NA
chr1	2962520	2963833	-	DDB_G0269542	DDB_G0269542_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr1	2963981	2965972	-	DDB_G0270886	DDB_G0270886_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr1	2966061	2966907	-	DDB_G0270888	DDB_G0270888_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr1	2967080	2967161	-	DDB_G0294785	tRNA-Ser-UGA-3	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr1	2967350	2968528	-	DDB_G0269544	act32	NA
chr1	2969017	2974040	+	DDB_G0269546	DDB_G0269546	ortholog of H. sapiens KIAA0528
chr1	2974419	2975425	-	DDB_G0269548	limG	contains 3 zinc-binding LIM domains%3B LIM domains are found in proteins with differing functions%2C including gene expression%2C and cytoskeleton organisation and development
chr1	2975759	2977120	+	DDB_G0269550	samm50	similar to the mammalian SAMM50 proteins%2C homologs of yeast SAM50%2C a component of the mitochondrial outer membrane sorting assembly complex
chr1	2978336	2980393	-	DDB_G0269188	snwA	SKIP ortholog%3B binds cyclophilin E (cypE) in a cyclosporin-independent manner
chr1	2981116	2981944	+	DDB_G0269104	calB	NA
chr1	2982129	2982680	-	DDB_G0269552	lsmd1	snRNP Sm family protein%3B similar to H. sapiens LSMD1%2C and to S. pombe U6 snRNP-associated protein Lsm7
chr1	2983180	2987875	+	DDB_G0269554	suvA	the D. melanogaster ortholog%2C su(var)3-9 has a central role in heterochromatin-induced gene silencing
chr1	2988150	2988932	+	DDB_G0270554	DDB_G0270554	NA
chr1	2989310	2990097	+	DDB_G0269556	DDB_G0269556	NA
chr1	2990411	2993319	-	DDB_G0269242	fcsA	catalyzes the reaction ATP %2B a long-chain carboxylic acid %2B CoA %3D AMP %2B diphosphate %2B an acyl-CoA%3B mediates the retrieval of fatty acids from endosomes to the cytoplasm
chr1	2994626	2996280	-	DDB_G0269558	gnt11	distant relative of CAZy family GT14%3B similar to xylosyltransferase
chr1	2996712	2998612	-	DDB_G0269560	DDB_G0269560	NA
chr1	2998816	2999433	+	DDB_G0269562	DDB_G0269562	NA
chr1	2999912	3000916	+	DDB_G0270556	syn1B	similar to syntaxin 1%2C a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr1	3001192	3001250	+	DDB_G0295495	r35	small non-coding RNA (59-60 nt) containing 5%27 and 3%27 ends predicted to form a stem structure%3B localizes to the cytoplasm
chr1	3002229	3006724	+	DDB_G0269210	abcG14	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr1	3007465	3008125	+	DDB_G0269176	racF1	NA
chr1	3008412	3008483	-	DDB_G0294783	tRNA-Glu-UUC-4	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	3009708	3012882	-	DDB_G0270828	DDB_G0270828	conserved protein of unknown function
chr1	3013601	3014302	-	DDB_G0269564	DDB_G0269564	NA
chr1	3015026	3015487	-	DDB_G0269566	DDB_G0269566	similar to D. purpureum protein
chr1	3016390	3017663	+	DDB_G0270558	DDB_G0270558	NA
chr1	3017741	3018878	-	DDB_G0269568	med7	ortholog of the mediator of RNA polymerase II transcription subunit 7%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr1	3019090	3020441	+	DDB_G0269570	rabggta	catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC%2C -XCXC and -CCXX C-terminal%3B forms a hetero-dimer with the %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0290671%22%3E%3Ci%3Ebeta%3C%2Fi%3E%3C%2Fa%3E subunit
chr1	3020703	3025206	-	DDB_G0269194	trfA	NA
chr1	3029557	3034180	+	DDB_G0269212	abcG11	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr1	3034894	3039544	-	DDB_G0269572	DDB_G0269572	similar to D. purpureum protein
chr1	3041058	3041915	-	DDB_G0269574	dcd3B	catalyzes the reaction N-acylsphingoside %2B H%3Csub%3E2%3C%2Fsub%3EO %3D a carboxylate %2B sphingosine
chr1	3042784	3047317	-	DDB_G0270560	mybP	contains two Myb DNA-binding domains%3B putative ortholog of the nuclear receptor corepressor 2 (also known as NCOR2%2C SMRT%2C TRAC and SMAP270 in mammalian cells)
chr1	3048022	3049597	-	DDB_G0270562	acy1	catalyzes the reaction: N-acyl-L-amino acid %2B H2O %3D  carboxylate %2B L-amino acid (EC 3.5.1.14)
chr1	3049822	3051393	+	DDB_G0269576	DDB_G0269576	contains one FAD-binding domain and one berberine like domain
chr1	3051829	3052746	-	DDB_G0269578	DDB_G0269578	NA
chr1	3054343	3055725	+	DDB_G0270564	DDB_G0270564	NA
chr1	3055800	3057686	-	DDB_G0269128	DDB_G0269128	contains two transmembrane domains%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0269128%22%3Ecommunity annotation%3C%2Fa%3E
chr1	3059126	3062012	-	DDB_G0269140	gapA	IQGAP-related protein involved in the completion of cytokinesis
chr1	3064049	3065362	+	DDB_G0269580	DDB_G0269580	NA
chr1	3066210	3069104	+	DDB_G0269582	DDB_G0269582	NA
chr1	3070710	3072419	+	DDB_G0270566	DDB_G0270566	the C-terminal DDHD domain is a metal binding domain often found in phospholipases
chr1	3072947	3074455	+	DDB_G0269584	DDB_G0269584	NA
chr1	3074692	3075105	-	DDB_G0269586	DDB_G0269586	NA
chr1	3075849	3077228	+	DDB_G0270568	DDB_G0270568	very similar to %3Ci%3ED. purpureum%3C%2Fi%3E protein
chr1	3077286	3078470	-	DDB_G0269588	DDB_G0269588	NA
chr1	3078895	3083055	-	DDB_G0269590	DDB_G0269590	contains 8 transmembrane domains
chr1	3083994	3085319	-	DDB_G0269592	DDB_G0269592	NA
chr1	3087129	3089970	+	DDB_G0269594	DDB_G0269594	NA
chr1	3090844	3091928	+	DDB_G0269596	DDB_G0269596	NA
chr1	3092703	3093698	+	DDB_G0269598	DDB_G0269598	NA
chr1	3093873	3094763	+	DDB_G0270570	DDB_G0270570	NA
chr1	3096057	3096885	+	DDB_G0270890	DDB_G0270890	NA
chr1	3096976	3098088	-	DDB_G0269600	DDB_G0269600	NA
chr1	3098695	3108214	+	DDB_G0270572	pks2	putative type I iterative polyketide synthase
chr1	3109107	3109977	+	DDB_G0270892	DDB_G0270892	NA
chr1	3110201	3111767	-	DDB_G0269602	slc35b2	putative adenosine 3%27-phospho 5%27-phosphosulfate transporter%3B belongs to the drug%2Fmetabolite transporter (DMT) superfamily%2C nucleotide-sugar transporter family%3B similar to human SLC35B2%3B contains 8 predicted transmembrane domains
chr1	3112632	3114887	+	DDB_G0270574	DDB_G0270574	NA
chr1	3115235	3116332	+	DDB_G0269604	DDB_G0269604_ps	putative pseudogene%3B fragment%2C similar to neighboring %3Ca href%3D%22%2Fgene%2FDDB_G0269606%22%3EDDB_G0269606%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270574%22%3EDDB_G0270574%3C%2Fa%3E
chr1	3116884	3119058	+	DDB_G0269606	DDB_G0269606	NA
chr1	3119127	3130279	-	DDB_G0269150	lvsA	contractile vacuole protein involved in response to hypoosmotic stress and required for cytokinesis
chr1	3131550	3134161	+	DDB_G0269608	DDB_G0269608	NA
chr1	3136522	3141488	+	DDB_G0269610	gxcT	interacts with racE%3B contains a RhoGEF domain%2C a pleckstrin homology (PH) domain%2C a C2H2-type zinc finger and an IQ calmodulin-binding domain
chr1	3141822	3144837	-	DDB_G0270578	DDB_G0270578	NA
chr1	3146250	3147915	+	DDB_G0269614	DDB_G0269614	NA
chr1	3148640	3149056	+	DDB_G0269616	aplG	splice variant A contains a putative signal peptide
chr1	3150646	3151839	+	DDB_G0269618	DDB_G0269618	NA
chr1	3152348	3153799	+	DDB_G0270580	DDB_G0270580	conserved protein of unknown function
chr1	3155421	3157129	+	DDB_G0270582	DDB_G0270582	peptidase M20 family zinc metallopeptidases%2C which are glutamate carboxypeptidases%3B contains peptidase dimerization domain
chr1	3157203	3158848	-	DDB_G0269246	pyd2	ortholog of the human DPYS%3B defects in DPYS cause cause of DHP (dihydropyrimidinase) deficiency%3B second enzyme in the reductive pyrimidine degradation pathway (EC 3.5.2.2)%3B catalyzes the reaction: 5%2C6-dihydrouracil %2B H%3Csub%3E2%3C%2Fsub%3EO %3D 3-ureidopropanoate
chr1	3159757	3161048	-	DDB_G0269620	DDB_G0269620	NA
chr1	3162116	3163141	-	DDB_G0269622	DDB_G0269622	NA
chr1	3163747	3164674	-	DDB_G0349030	DDB_G0349030	NA
chr1	3164918	3165853	-	DDB_G0270584	DDB_G0270584	NA
chr1	3166724	3168412	-	DDB_G0269112	celB	NA
chr1	3170314	3174422	+	DDB_G0269624	mgp3	NA
chr1	3176439	3181124	+	DDB_G0269626	forE	NA
chr1	3181593	3183333	+	DDB_G0270586	DDB_G0270586	NA
chr1	3183487	3185815	-	DDB_G0269628	DDB_G0269628	putative protein serine%2Fthreonine kinase%3B similar to vertebrate Nek kinases which are involved in regulation of mitosis
chr1	3187028	3188197	-	DDB_G0269630	iliI	belongs to a superfamily of metalloenzymes%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr1	3189061	3189405	+	DDB_G0270588	DDB_G0270588	NA
chr1	3189743	3189948	-	DDB_G0295497	rnu2b	component of the spliceosome involved in pre-mRNA splicing
chr1	3190841	3195534	+	DDB_G0269632	irlD	the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy
chr1	3195968	3200425	+	DDB_G0270894	irlC	the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy%3B contains a SWIM Zn-finger domain
chr1	3201588	3202019	+	DDB_G0269634	DDB_G0269634	NA
chr1	3202239	3203453	-	DDB_G0269636	DDB_G0269636	NA
chr1	3204015	3204688	-	DDB_G0269638	dr1	similar to the mammalian down-regulator of transcription 1
chr1	3205382	3206294	-	DDB_G0269640	DDB_G0269640	NA
chr1	3206739	3208141	+	DDB_G0269642	mak16l	ortholog of S. cerevisiae MAK16 and mammalian RBM13%3B inyeast an essential nuclear protein%2C constituent of 66S pre-ribosomal particles
chr1	3209615	3211648	+	DDB_G0270590	DDB_G0270590	NA
chr1	3212380	3212770	+	DDB_G0270592	DDB_G0270592	NA
chr1	3214845	3216721	+	DDB_G0269644	DDB_G0269644	NA
chr1	3217078	3218041	-	DDB_G0269646	DDB_G0269646	NA
chr1	3218681	3219264	+	DDB_G0269648	DDB_G0269648	NA
chr1	3221057	3221731	-	DDB_G0270896	DDB_G0270896_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	3222819	3222890	+	DDB_G0294735	tRNA-Thr-AGU-9	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	3223232	3225869	-	DDB_G0270898	DDB_G0270898	NA
chr1	3226604	3229060	-	DDB_G0269180	rcdP	NA
chr1	3230494	3230637	-	DDB_G0269650	DDB_G0269650	NA
chr1	3231014	3232274	-	DDB_G0269652	DDB_G0269652	NA
chr1	3233164	3235474	+	DDB_G0269654	DDB_G0269654_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0269656%22%3EDDB_G0269656%3C%2Fa%3E
chr1	3235920	3238114	+	DDB_G0269656	DDB_G0269656	NA
chr1	3239824	3244143	+	DDB_G0270902	DDB_G0270902	NA
chr1	3244376	3246648	-	DDB_G0269108	catB	catalyzes the reaction 2H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E %2B catalase %3D%3E 2H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E%3B only expressed in post-aggregative development in prespore cells%3B regulated by the MADS-box transcription factor SrfA during development
chr1	3247124	3247418	-	DDB_G0270594	DDB_G0270594	NA
chr1	3247871	3248759	+	DDB_G0269658	DDB_G0269658	NA
chr1	3249734	3250465	-	DDB_G0270904	cyp508E1_ps	putative pseudogene%3B related to the cytochrome P450 family
chr1	3250824	3252752	-	DDB_G0270596	DDB_G0270596	NA
chr1	3253076	3254603	-	DDB_G0270598	DDB_G0270598	NA
chr1	3256805	3256877	-	DDB_G0294781	tRNA-Ile-AAU-5	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr1	3257172	3257666	+	DDB_G0269662	DDB_G0269662_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr1	3259661	3261385	+	DDB_G0269228	DDB_G0269228	NA
chr1	3261649	3263130	-	DDB_G0269196	tubB	NA
chr1	3265296	3266203	+	DDB_G0269664	DDB_G0269664	NA
chr1	3267307	3268805	+	DDB_G0269248	cf45-1	component of the counting factor complex%2C which includes CF60%2C CF50%2C CF45-1%2C and CtnA (countin)
chr1	3269066	3269405	-	DDB_G0295751	DDB_G0295751	conserved %3Ci%3ED. discoideum%3C%2Fi%3E protein
chr1	3270165	3271230	-	DDB_G0270600	DDB_G0270600	NA
chr1	3271877	3272023	-	DDB_G0270602	drnA_ps	putative pseudogene%3B small fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0273051%22%3E%3Ci%3EdrnA%3C%2Fi%3E%3C%2Fa%3E 
chr1	3272420	3272761	-	DDB_G0270604	DDB_G0270604	conserved %3Ci%3ED. discoideum%3C%2Fi%3E protein
chr1	3273351	3273836	-	DDB_G0269666	DDB_G0269666	NA
chr1	3274209	3277152	+	DDB_G0269154	modA	NA
chr1	3278152	3278565	-	DDB_G0269668	DDB_G0269668	NA
chr1	3279591	3281482	-	DDB_G0269670	DDB_G0269670	contains one C2 domain%2C which is thought to be involved in calcium-dependent phospholipid binding%3B also contains one WW domain%2C which is involved in protein binding
chr1	3282508	3282723	+	DDB_G0269672	DDB_G0269672	expressed in pstO cells and in pstO cells and upper cup during culmination
chr1	3283385	3283606	+	DDB_G0269674	DDB_G0269674	expressed in pstO cells
chr1	3287288	3289621	+	DDB_G0270606	DDB_G0270606	NA
chr1	3289699	3291350	-	DDB_G0269676	DDB_G0269676	NA
chr1	3291492	3292937	+	DDB_G0270906	jcdD	putative ortholog of H. sapiens JMJD5
chr1	3293315	3296614	+	DDB_G0270910	DDB_G0270910	NA
chr1	3297321	3297636	-	DDB_G0270912	DDB_G0270912	similar to D. purpureum protein
chr1	3299624	3300197	-	DDB_G0270610	DDB_G0270610	NA
chr1	3301231	3305445	-	DDB_G0269678	fuk	catalyzes the reaction: ATP %2B L-fucose %3D ADP %2B beta-L-fucose 1-phosphate
chr1	3305788	3308565	-	DDB_G0269680	DDB_G0269680	NA
chr1	3309660	3313064	-	DDB_G0269682	atxn2	similar to the human ataxin-2 (ATXN2)%3B defects in the gene cause spinocerebellar ataxia 2 (SCA2)
chr1	3314085	3314155	-	DDB_G0294779	tRNA-Pro-UGG-4	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr1	3314988	3316261	-	DDB_G0269202	gdcA	NA
chr1	3317582	3319144	-	DDB_G0269684	DDB_G0269684	shares a short region of similarity with cell division cycle associated 3 (CDCA3%2FTOME-1)%2C in particular the presence of two DPRSPS%2FT(xxx)RTP repeats%3B characterized in Xenopus as a F-box-like protein required for entry into mitosis and that participates in the E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2%2FM phase %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0269684 is weakly similar to tome-1 (Trigger of Mitotic Entry)%2C also known as cdcA3%2C  a gene first characterized in the mouse%2C which is also found throughout the metazoans%3B  budding yeast also contains a related gene%2C %3Ca target %3D %22new%22 href%3D%22http:%2F%2Fwww.yeastgenome.org%2Fcgi-bin%2Flocus.fpl?dbid%3DS000003737%22%3EYJL201W%3C%2Fa%3E. Tome-1 is an F-box protein which  associates with the E3 ubiquitin ligase skp-1 and mediates the destruction of the cdk  inhibitory kinase wee1 (%3Ca target %3D %22new%22 href%3D%22http:%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F12679038%22%3EAyad et al 2003%3C%2Fa%3E). The yeast gene is weakly  but clearly cell-cycle regulated%2C but the expression peak is not in G2%2C as one might expect  for a mitotic protein%2C but in G1. %3Cbr%2F%3E  DDB_G0269684 is overexpressed fourfold in the Dictyostelium %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E%2C a strain in  which most genes associated with cell cycle progression are overexpressed  (Doquang et al%2C in preparation).  This suggests an active role of rif1 in telomere replication.   %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C May 2009 %3C%2Fi%3E
chr1	3319946	3322896	-	DDB_G0269686	DDB_G0269686	shares a short region of similarity with H. sapiens IQ motif and WD repeats-containing protein 1 IQWD1 
chr1	3323737	3326298	-	DDB_G0269688	sdad1	conserved protein%2C in S.cerevisiae required for 60S pre-ribosomal subunits export to the cytoplasm
chr1	3326879	3327586	-	DDB_G0270614	DDB_G0270614	NA
chr1	3328824	3329816	+	DDB_G0270914	DDB_G0270914	NA
chr1	3330425	3331198	+	DDB_G0270916	DDB_G0270916	NA
chr1	3332298	3336672	+	DDB_G0270918	DDB_G0270918	DENN domains are present in proteins involved in Rab signaling
chr1	3337065	3338927	+	DDB_G0269692	DDB_G0269692	NA
chr1	3339032	3343830	-	DDB_G0269694	pan2	ortholog of PAN2%2C a member of the Pan2p-Pan3p poly(A)-ribonuclease complex%2C which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes
chr1	3345400	3350536	+	DDB_G0269696	pakD	similar to Dictyostelium pakA and other mitogen-activated protein kinases (Ste20%2FPAK family)%3B putative p21-activated kinase%3B contains a calponin-like actin-binding domain%2C a p21-Rho-binding domain%2C and a PKC conserved region 1 (C1)%3B regulates the actin cytoskeleton response during chemotaxis to cAMP
chr1	3350709	3351586	-	DDB_G0269698	DDB_G0269698	contains a putative signal peptide and 8 transmembrane regions
chr1	3352107	3354728	+	DDB_G0269700	DDB_G0269700	NA
chr1	3354771	3358939	-	DDB_G0269172	pspC	NA
chr1	3360340	3361265	+	DDB_G0269240	racH	small GTPase involved in regulation of vesicle trafficking through regulation of actin polymerization
chr1	3361680	3363770	-	DDB_G0270830	bopA	similar to mouse BOP%2C a zinc finger protein
chr1	3364045	3365508	+	DDB_G0270618	DDB_G0270618	contains 4 WD-40 repeats
chr1	3365719	3366285	-	DDB_G0269702	DDB_G0269702	expressed in pstAB cells and in pstA cells%2C pstO cells%2C upper and lower cups%2C and stalk during culmination
chr1	3367372	3368994	-	DDB_G0269704	DDB_G0269704	NA
chr1	3369226	3369472	+	DDB_G0270620	DDB_G0270620	NA
chr1	3369734	3371095	-	DDB_G0271094	fah	catalyzes the reaction 4-fumarylacetoacetate %2B H%3Csub%3E2%3C%2Fsub%3EO %3D acetoacetate %2B fumarate
chr1	3371521	3372496	-	DDB_G0269120	cypB	NA
chr1	3373104	3374984	+	DDB_G0269706	DDB_G0269706	NA
chr1	3375140	3378478	-	DDB_G0270920	DDB_G0270920	contains no functional domains and is not similar to any other protein
chr1	3379646	3380666	+	DDB_G0269708	DDB_G0269708	contains an actin-binding WH2 (Wiskott Aldrich syndrome homology region 2) domain near its N-terminus%2C and a C-terminal SH3 (src Homology-3) domain%3B predicted to have an N-terminal signal peptide
chr1	3381332	3381974	+	DDB_G0270922	DDB_G0270922	NA
chr1	3383025	3383458	+	DDB_G0270924	DDB_G0270924	NA
chr1	3383680	3388102	-	DDB_G0269710	DDB_G0269710	NA
chr1	3388870	3390021	-	DDB_G0269712	ahsa	NA
chr1	3391069	3391491	+	DDB_G0270622	DDB_G0270622	NA
chr1	3391649	3393035	-	DDB_G0269714	tdo	catalyzes the reactoin L-tryptophan %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E L-formylkynurenine
chr1	3393751	3394743	+	DDB_G0270926	DDB_G0270926	NA
chr1	3394961	3395551	-	DDB_G0270624	DDB_G0270624	NA
chr1	3397004	3398144	-	DDB_G0269716	DDB_G0269716	NA
chr1	3398987	3400602	+	DDB_G0270928	sir2E	NAD-dependent deacetylase Sirutin 2 family protein%2C that regulate various biological processes by deacetylating histones and other target proteins%3B nuclear protein%2C expressed in pstA and pstO cells in the slug%2C and to the apical disc%2C upper and lower cups in the culminant (similar expression pattern as sir2B) 
chr1	3402124	3406095	-	DDB_G0269718	DDB_G0269718	NA
chr1	3410490	3413579	-	DDB_G0269720	abcB7	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr1	3414230	3415170	+	DDB_G0269722	DDB_G0269722	belongs to the methyltransferase superfamily%3B ortholog of human WBSCR22%2C an uncharacterized methyltransferase associated with Williams-Beuren syndrome
chr1	3418520	3423103	+	DDB_G0270932	DDB_G0270932	NA
chr1	3424394	3425573	+	DDB_G0269724	DDB_G0269724	NA
chr1	3425762	3426901	-	DDB_G0269726	pggt1b	catalyzes the reaction geranylgeranyl diphosphate %2B protein-cysteine %3D S-geranylgeranyl-protein %2B diphosphate
chr1	3427650	3428995	+	DDB_G0269728	ciao1	ortholog of the conserved CIA1 (%3Ci%3ES. cerevisiae%3C%2Fi%3E) or CIAO1 (Mammals)%2C which in yeast is essential for assembly of cytosolic and nuclear iron-sulfur proteins%3B contains 7 WD40 repeats
chr1	3429232	3429774	-	DDB_G0269730	DDB_G0269730	NA
chr1	3431040	3431112	-	DDB_G0294777	tRNA-Asn-GUU-6	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr1	3431190	3431262	-	DDB_G0294775	tRNA-Ala-AGC-1	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr1	3432396	3434782	+	DDB_G0270826	abcG22	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr1	3436536	3441900	+	DDB_G0269166	pakA	STE20%2FPAKA protein kinase involved in the regulation of the cytoskeleton during chemotaxis and required for cytokinesis%3B contains PAK-box%2FP21-Rho-binding (CRIB) domain found in the WASP C-terminal
chr1	3443410	3446174	+	DDB_G0269732	DDB_G0269732	NA
chr1	3447052	3449746	+	DDB_G0270626	armc8	ortholog of the conserved armadillo repeat containing 8 protein
chr1	3450462	3451264	+	DDB_G0269734	DDB_G0269734	NA
chr1	3451792	3454310	-	DDB_G0269736	DDB_G0269736	NA
chr1	3455193	3456362	+	DDB_G0269738	desA	reduces dihydroceramide to ceramide in sphingolipid biosynthesis
chr1	3456576	3460406	+	DDB_G0270628	DDB_G0270628	NA
chr1	3461467	3462395	-	DDB_G0269216	cypE	cyclosporin A-sensitive peptidylprolyl cis-trans isomerase%3B binds the SKIP ortholog snwA in a cyclosporin-independent manner
chr1	3463314	3465781	+	DDB_G0269740	DDB_G0269740	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D
chr1	3466584	3468271	+	DDB_G0269742	cdsA	catalyzes the reaction: CTP %2B phosphatidate %3D diphosphate %2B CDP-diacylglycerol%3B provides CDP-diacylglycerol an important precursor for the synthesis of phospholipids%3B contains 8 putative transmembrane domains
chr1	3468500	3469879	-	DDB_G0269744	DDB_G0269744	NA
chr1	3470541	3471348	+	DDB_G0270630	DDB_G0270630	NA
chr1	3471589	3472824	+	DDB_G0269746	itpk1	phosphorylates 1D-myo-inositol 3%2C4%2C5%2C6-tetrakisphosphate to 1D-myo-inositol 1%2C3%2C4%2C5%2C6-pentakisphosphate
chr1	3473013	3474697	-	DDB_G0269748	DDB_G0269748	NA
chr1	3476704	3479389	-	DDB_G0269226	cas1	NA
chr1	3480476	3481471	+	DDB_G0269750	DDB_G0269750	NA
chr1	3482394	3483543	-	DDB_G0269752	DDB_G0269752_ps	putative pseudogene%3B similar to parts of %3Ca href%3D%22%2Fgene%2FDDB_G0277693%22%3EDDB_G0277693%3C%2Fa%3E
chr1	3484288	3485533	+	DDB_G0269754	DDB_G0269754	NA
chr1	3485944	3487242	-	DDB_G0270934	DDB_G0270934	NA
chr1	3488110	3489009	-	DDB_G0270936	DDB_G0270936	NA
chr1	3489330	3491399	-	DDB_G0269756	DDB_G0269756	belongs to the crotonase superfamily
chr1	3492337	3494799	-	DDB_G0270632	DDB_G0270632	NA
chr1	3495532	3496368	+	DDB_G0270938	DDB_G0270938_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0281463%22%3EDDB_G0281463%3C%2Fa%3E
chr1	3496969	3500265	+	DDB_G0269758	DDB_G0269758	NA
chr1	3500588	3503767	-	DDB_G0269124	dcsA	CAZy family GT2%3B catalyzes the reaction UDP-glucose %2B (1%2C4-beta-D-glucosyl)n %3C%3D%3E UDP %2B (1%2C4-beta-D-glucosyl)n%2B1
chr1	3508370	3509356	-	DDB_G0270940	DDB_G0270940	NA
chr1	3510769	3511836	+	DDB_G0269760	DDB_G0269760	one of many putative Dictyostelium potassium channels%3B contains 3 pentapeptide repeats
chr1	3512075	3514549	-	DDB_G0269762	DDB_G0269762	NA
chr1	3515795	3517258	+	DDB_G0269764	cnrC	identified as a suppressor of smlA null mutant cnr3%3B has a predicted signal anchor sequence
chr1	3517400	3517872	-	DDB_G0269766	DDB_G0269766	similar to UPF0451 family proteins%3B contains 3 predicted transmembrane domains%3B there is an almost identical gene%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0270942%22%3E DDB_G0270942%3C%2Fa%3E upstream
chr1	3518935	3519427	-	DDB_G0270942	DDB_G0270942	similar to UPF0451 family proteins%3B contains 3 predicted transmembrane domains%3B there is an almost identical gene%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0269766%22%3E DDB_G0269766 %3C%2Fa%3E downstream
chr1	3520960	3522817	+	DDB_G0269768	cnrI	identified as a suppressor of smlA null mutant cnr9 
chr1	3523265	3524869	-	DDB_G0269770	fam63A	NA
chr1	3525818	3526839	+	DDB_G0269772	psmB3	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr1	3527142	3528263	+	DDB_G0269774	DDB_G0269774	NA
chr1	3528359	3529764	-	DDB_G0269776	DDB_G0269776	NA
chr1	3530459	3532109	+	DDB_G0270634	DDB_G0270634	similar to TNRC4 (TriNucleotide Repeat Containing 4 protein) and Bruno-like proteins%3B contains 3 RRM domains
chr1	3534092	3537641	+	DDB_G0270636	DDB_G0270636	contains two predicted transmembrane domains%3B one at amino terminus and one at carboxyl terminus
chr1	3537960	3539386	+	DDB_G0269192	tifA	similar to eukaryotic initiation factor 4A%2C isoform 3
chr1	3539581	3544525	-	DDB_G0269222	gefB	promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form
chr1	3547267	3548768	+	DDB_G0269778	DDB_G0269778	NA
chr1	3549387	3553055	+	DDB_G0269780	DDB_G0269780	NA
chr1	3553343	3554182	-	DDB_G0269782	DDB_G0269782	NA
chr1	3555282	3556079	+	DDB_G0269784	DDB_G0269784	NA
chr1	3556678	3557509	+	DDB_G0269786	ccdc25	ortholog of the widely conserved CCDC25 protein
chr1	3558146	3559074	+	DDB_G0269788	DDB_G0269788	catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis%3B almost identical to the neighboring gene %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0270946%22%3E%3Ci%3EDDB_G0270946%3C%2Fi%3E%3C%2Fa%3E
chr1	3559643	3560529	+	DDB_G0270946	DDB_G0270946	catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis%3B almost identical to the neighboring gene %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0269788%22%3E%3Ci%3EDDB_G0269788%3C%2Fi%3E%3C%2Fa%3E
chr1	3561059	3562855	+	DDB_G0270948	fntB	catalyzes the transfer of a farnesyl group or a geranylgeranyl group via a thioether linkage (-C-S-C-) to a cysteine at or near the carboxyl terminus of the protein%3B forms a heterodimer with the %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283053%22%3E%3Ci%3Ealpha%3C%2Fi%3E%3C%2Fa%3E subunit
chr1	3563596	3566431	+	DDB_G0269790	gaa	ortholog of the %3Ci%3EH. sapiens%3C%2Fi%3E lysosomal alpha-glucosidase which is essential for the degradation of glygogen to glucose in lysosomes%3B defects in GAA are the cause of glycogen storage disease II%2C a recessive disorder which results in a massive accumulation of glycogen in muscle%2C heart and liver leading to a life expectancy of less than two years
chr1	3567457	3570891	-	DDB_G0270950	DDB_G0270950_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr1	3572251	3573399	+	DDB_G0270952	DDB_G0270952_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr1	3573682	3577683	+	DDB_G0270954	DDB_G0270954_RTE	long terminal repeat retrotransposon Skipper GAG-PRO-POL%3B refer to GenBank AF049230 for full length consensus element
chr1	3577989	3579341	-	DDB_G0270638	DDB_G0270638_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr1	3579771	3579843	+	DDB_G0294737	tRNA-Asn-GUU-5	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr1	3580948	3581715	+	DDB_G0269794	DDB_G0269794	NA
chr1	3581899	3584968	-	DDB_G0270640	DDB_G0270640	matches PFAM HMM for SPB_interacting (spindle pole body) protein%3B similar to D.purpureum protein
chr1	3586235	3588840	-	DDB_G0270642	DDB_G0270642	NA
chr1	3588898	3595338	+	DDB_G0269796	DDB_G0269796_ps	putative pseudogene%3B highly similar to %3Ca href%3D%22%2Fgene%2FDDB_G0270962%22%3EDDB_G0270962%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270480%22%3EDDB_G0270480%3C%2Fa%3E
chr1	3595722	3598413	-	DDB_G0270958	DDB_G0270958	NA
chr1	3599415	3609732	+	DDB_G0270962	DDB_G0270962	contains a predicted signal peptide
chr1	3610258	3612888	-	DDB_G0270644	DDB_G0270644	NA
chr1	3613525	3615579	+	DDB_G0295763	DDB_G0295763	NA
chr1	3616147	3626352	+	DDB_G0270964	DDB_G0270964_ps	putative pseudogene%3B highly similar to %3Ca href%3D%22%2Fgene%2FDDB_G0270962%22%3EDDB_G0270962%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270480%22%3EDDB_G0270480%3C%2Fa%3E
chr1	3627252	3628552	+	DDB_G0270966	DDB_G0270966	NA
chr1	3628624	3631009	-	DDB_G0269800	DDB_G0269800	putative ortholog of the conserved chromatin assembly factor 1 (CAF1) subunit B%3Cbr%3E %3Cb%3ENote:%3C%2Fb%3E Do not confuse this gene with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277827%22%3E%3Ci%3EcafA%3C%2Fi%3E%3C%2Fa%3E%2C calfumirin 1%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Although the homology of DDB_G0269800 to CAF1%2C subunit B is weak%2C the assignment is supported by the fact that this gene is overexpressed sevenfold in a Dicty strain in which the retinoblastoma-like gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E%2C is disrupted (Doquang et al%2C in preparation).  Most genes with roles in S-phase or mitosis are overexpressed in this strain. Chromatin assembly is of course a part of normal DNA replication%2C and %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0287815%22%3EDDB_G0287815%3C%2Fa%3E%2C provisionally assigned as CAF1%2C subunit A%2C is similarly overexpressed in the rblA null.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C September 2009 %3C%2Fi%3E 
chr1	3631591	3633444	+	DDB_G0269802	DDB_G0269802	NA
chr1	3633884	3635911	+	DDB_G0270646	DDB_G0270646	NA
chr1	3637012	3637461	+	DDB_G0269804	DDB_G0269804	NA
chr1	3639054	3640202	-	DDB_G0270648	DDB_G0270648_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	3640332	3641360	-	DDB_G0270650	DDB_G0270650_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	3642654	3643730	-	DDB_G0270968	DDB_G0270968_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr1	3644185	3644256	-	DDB_G0294773	tRNA-Thr-AGU-12	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	3644457	3645638	-	DDB_G0270970	DDB_G0270970	NA
chr1	3645779	3646132	-	DDB_G0269806	DDB_G0269806	NA
chr1	3646239	3646703	-	DDB_G0269808	DDB_G0269808	NA
chr1	3647265	3648460	+	DDB_G0270652	DDB_G0270652	sulfurates the molybdenum cofactor%2C which is essential for xanthine dehydrogenase and aldehyde oxidase
chr1	3649783	3652408	+	DDB_G0269156	mvpA	NA
chr1	3653375	3655402	-	DDB_G0307697	DDB_G0307697	NA
chr1	3656011	3658191	-	DDB_G0307694	DDB_G0307694	NA
chr1	3658614	3659264	-	DDB_G0269812	DDB_G0269812	NA
chr1	3660860	3661468	+	DDB_G0270654	DDB_G0270654	NA
chr1	3661674	3664325	-	DDB_G0269814	ncbp1	ortholog of mammalian NCPB1 and yeast STO1%3B large subunit of the heterodimeric cap binding complex involved in mediating U snRNA export from the nucleus
chr1	3664995	3666427	+	DDB_G0269816	DDB_G0269816	ortholog of the mammalian kin17 protein%2C a zinc finger nuclear protein
chr1	3667020	3667381	-	DDB_G0269818	DDB_G0269818	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr1	3667800	3668045	+	DDB_G0270656	DDB_G0270656_ps	putative pseudogene%3B hssA%2F2C%2F7E family gene
chr1	3669036	3669397	+	DDB_G0269820	DDB_G0269820	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr1	3669575	3671080	-	DDB_G0269822	mhisS	catalyzes the reaction ATP %2B L-histidine %2B tRNAHis %3D AMP %2B diphosphate %2B L-histidyl-tRNAHis%3B similar to bacterial histidine-tRNA ligase
chr1	3671523	3672995	+	DDB_G0269824	DDB_G0269824	NA
chr1	3673860	3674359	+	DDB_G0270658	acbA	precursor of SDF-2%3B similar to diazepam binding inhibitor%3B enriched in prespore cells
chr1	3675572	3680023	-	DDB_G0269826	DDB_G0269826	NA
chr1	3681011	3682051	+	DDB_G0270836	fbp	hydrolyses D-fructose 1%2C6-bisphosphate to D-fructose 6-phosphate and phosphate (EC 3.1.3.11)
chr1	3682321	3683577	+	DDB_G0269828	DDB_G0269828	putative ortholog of SSSCA1 (Sjogrens syndrome scleroderma autoantigen 1)%2C that might play a role in mitosis
chr1	3683818	3685422	-	DDB_G0269830	DDB_G0269830	NA
chr1	3685708	3686529	+	DDB_G0269832	DDB_G0269832	NA
chr1	3686674	3687885	-	DDB_G0269834	DDB_G0269834	NA
chr1	3688411	3689196	-	DDB_G0269836	DDB_G0269836	NA
chr1	3690037	3690714	+	DDB_G0269838	DDB_G0269838	NA
chr1	3691172	3692200	-	DDB_G0270972	DDB_G0270972	ortholog of human OVCA2 gene associated with ovarian cancer
chr1	3694605	3695020	-	DDB_G0270974	DDB_G0270974	NA
chr1	3695166	3695738	-	DDB_G0270660	DDB_G0270660	NA
chr1	3696190	3696483	-	DDB_G0270662	DDB_G0270662	NA
chr1	3697371	3699160	-	DDB_G0269840	DDB_G0269840	contains one putative transmembrane domain%3B similar to D. purpureum protein
chr1	3699523	3701813	+	DDB_G0270664	DDB_G0270664	NA
chr1	3701971	3707422	-	DDB_G0269842	DDB_G0269842	contains two C2H2-type zinc finger domains%3B contains one coiled-coil domain
chr1	3709558	3709683	-	DDB_G0269844	DDB_G0269844	NA
chr1	3710387	3710746	-	DDB_G0269846	DDB_G0269846	NA
chr1	3711642	3713063	+	DDB_G0269848	agpA	belongs to the acyltransferase superfamily%3B contains 2 predicted transmembrane domains
chr1	3713353	3718689	-	DDB_G0270666	gdt2	member of the TKL (tyrosine kinase-like) group and the GDT family%3B putative transmembrane protein
chr1	3719484	3722655	+	DDB_G0269850	DDB_G0269850	contains a signal peptide and a single predicted transmembrane domain at the C-terminus%3B small gene family in D. discoideum%3B D. purpureum has a single gene
chr1	3723386	3727938	-	DDB_G0270668	gdt8	member of the TKL (tyrosine kinase-like) group and the GDT family%3B putative transmembrane protein
chr1	3728354	3728923	-	DDB_G0269852	psaB_ps	putative pseudogene%3B fragment%2C similar to the puromycin-sensitive aminopeptidase-like protein %3Ca href%3D%22%2Fgene%2FDDB_G0270670%22%3EpsaB%3C%2Fa%3E
chr1	3731263	3734083	+	DDB_G0270670	psaB	highly similar to mammalian puromycin-sensitive aminopeptidase belonging to the peptidase M1 family (metallopeptidases)%3B contains a peptidase M1 domain including a zinc-binding site
chr1	3734477	3734926	+	DDB_G0269220	DDB_G0269220	subunit VIb of cytochrome c oxidase%2C the terminal member of the mitochondrial inner membrane electron transport chain
chr1	3735334	3735939	-	DDB_G0269178	racG	Rho family GTPase that positively regulates actin filament formation during phagocytosis and chemotaxis
chr1	3736784	3737308	-	DDB_G0269218	lyrm7	belongs to a family of short proteins that includes proteins from the NADH-ubiquinone oxidoreductase complex I%3B named LYR after a highly conserved tripeptide motif
chr1	3737738	3739165	-	DDB_G0269854	amdhd1	catalyzes the reaction (S)-3-(5-oxo-4%2C5-dihydro-3H-imidazol-4-yl)propanoate %2B H2O %3D N-formimidoyl-L-glutamate %2B H%2B
chr1	3740758	3742851	-	DDB_G0270672	fslN	has similarity to G-protein-coupled receptors%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr1	3743580	3744917	+	DDB_G0269856	ddcA	similar to diaminopimelate decarboxylase%2C which catalyzes the reaction meso-2%2C6-diaminoheptanedioate %3D L-lysine %2B CO%3Csub%3E2%3C%2Fsub%3E
chr1	3745025	3746842	-	DDB_G0269858	DDB_G0269858	NA
chr1	3747132	3750705	+	DDB_G0269860	DDB_G0269860	similar to importin-7 and importin-8 from numerous eukaryotes%3B involved in nuclear protein import
chr1	3751652	3752725	+	DDB_G0269254	sigJ	weakly related to blackjack%2C a protein associated with microtubules but without similarity to MAPs%3B regulated by the MADS-box transcription factor SrfA during development%3B expressed in prespore cells
chr1	3754803	3755264	-	DDB_G0270976	DDB_G0270976_ps	putative pseudogene%3B fragment%2C similar to laminin-type EGF-like domain-containing proteins such as %3Ca href%3D%22%2Fgene%2FDDB_G0289399%22%3EDDB_G0289399%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0287667%22%3EDDB_G0287667%3C%2Fa%3E
chr1	3757657	3758811	-	DDB_G0270978	DDB_G0270978	conserved protein of unknown function%3B contains a putative signal peptide followed by a transmembrane domain
chr1	3763159	3765064	-	DDB_G0269864	DDB_G0269864	NA
chr1	3766207	3766797	+	DDB_G0270980	DDB_G0270980	NA
chr1	3767514	3767807	+	DDB_G0269866	DDB_G0269866	NA
chr1	3768283	3768998	+	DDB_G0269870	DDB_G0269870	NA
chr1	3769162	3770134	-	DDB_G0269872	tspB	similar to the mammalian CD9 antigen%3B contains a tetraspanin and 4 putative transmembrane domains
chr1	3771006	3771407	+	DDB_G0270982	DDB_G0270982	NA
chr1	3772004	3772650	+	DDB_G0270984	rpl36a	protein component of the large (60S) ribosomal subunit
chr1	3773813	3775000	+	DDB_G0269874	DDB_G0269874	NA
chr1	3775693	3777740	+	DDB_G0269876	samkA	contains a SAM (sterile alpha motif) domain and a putative EF hand
chr1	3778203	3780924	+	DDB_G0270678	samkC	putative protein kinase containing a SAM (sterile alpha motif) homology domain%2C a putative protein interaction module
chr1	3781297	3783053	+	DDB_G0270680	samkD	similar to SNF1-like kinases%3B unlikely to function as a kinase as it lacks the catalytic aspartate
chr1	3783828	3785196	+	DDB_G0269878	fbl	utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2%27-hydroxyl methylation of ribose moieties in pre-ribosomal RNA
chr1	3785577	3786992	+	DDB_G0269880	DDB_G0269880	conserved protein%3B may catalyze reversible transfer reactions of coenzyme A groups from CoA-thioesters to free acids
chr1	3787682	3788230	+	DDB_G0269882	DDB_G0269882	similar to bacterial outer membrane lipoprotein Blc%3B lipocalins are involved in the binding and transport of small molecules such as lipids%2C steroid hormones%2C bilins%2C and retinoids
chr1	3789005	3790079	+	DDB_G0270986	tspC	similar to the mammalian CD9 antigen%3B contains a tetraspanin and 4 putative transmembrane domains
chr1	3791042	3792853	-	DDB_G0270988	samkB_ps1	putative pseudogene%3B SAMK (SAM domain-containing kinase) family
chr1	3795204	3796160	+	DDB_G0269110	tspA	similar to the mammalian CD9 antigen%3B contains a tetraspanin and 4 putative transmembrane domains
chr1	3796607	3797645	+	DDB_G0270682	tspD	similar to the mammalian CD9 antigen%3B contains a tetraspanin and 4 putative transmembrane domains
chr1	3797962	3800493	+	DDB_G0269884	DDB_G0269884	NA
chr1	3801076	3802258	+	DDB_G0269886	DDB_G0269886	NA
chr1	3802780	3803589	+	DDB_G0269888	DDB_G0269888	NA
chr1	3803772	3804667	+	DDB_G0269890	DDB_G0269890	ortholog of human APOA1BP%2C S. pombe mug182
chr1	3806514	3807971	+	DDB_G0269892	DDB_G0269892	NA
chr1	3809035	3810441	+	DDB_G0269182	rsc5	some members of this family have guanine nucleotide exchange activity
chr1	3810811	3812262	+	DDB_G0269894	orcB	DNA replication initiation is driven by a conserved six protein complex%2C the origin recognition complex (ORC)%3B has a role in both chromosomal replication and mating type transcriptional silencing
chr1	3812473	3816336	-	DDB_G0269896	kcnma1	ortholog of the human KCNMA1%2C  a potassium channel activated by both membrane depolarization and increase in cytosolic Ca(2%2B) that mediates export of K(%2B)%3B defects in the gene cause generalized epilepsy and paroxysmal dyskinesia (GEPD)
chr1	3817626	3819202	-	DDB_G0269130	phgA	conserved protein involved in contractile vacuole discharge upon osmotic stress%3Cbr%2F%3E %3Cb%3ENomenclature conflict: %3C%2Fb%3E Do not confuse this gene with phg1a%2C encoding  the putative phagocytic receptor 1a%2C or with the phgA locus (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Freference%2Freference.pl?refNo%3D1446%22%3EDuffy and Vogel 1984%3C%2Fa%3E)
chr1	3820454	3823469	+	DDB_G0269898	DDB_G0269898	NA
chr1	3823854	3826081	+	DDB_G0269900	gnt10	distant relative of CAZy family GT14%3B similar to xylosyltransferase
chr1	3826453	3827580	+	DDB_G0269902	act26	has 64%25 identity with human beta-actin (SwissProt P60709)
chr1	3827661	3827938	-	DDB_G0269904	DDB_G0269904	NA
chr1	3829651	3830649	-	DDB_G0270686	DDB_G0270686	NA
chr1	3831161	3831468	+	DDB_G0269906	gtf2h5	general transcription factor required for the initiation of transcription by RNA polymerase II and in nucleotide excision repair
chr1	3831693	3832921	-	DDB_G0269908	DDB_G0269908	ortholog of human FA2H%2C S. cerevisiae SCS7%3B contains a cytochrome b5 heme-binding domain and 4 predicted transmembrane domains
chr1	3834760	3836838	+	DDB_G0270990	DDB_G0270990	very similar to acyl-coenzyme A oxidases%2C but lacks the full domain
chr1	3837509	3841658	+	DDB_G0270992	sec31	component of COPII (coat protein complex II) involved in ER to Golgi transport
chr1	3842009	3844717	+	DDB_G0270994	psaA	highly similar to mammalian puromycin-sensitive aminopeptidase belonging to the peptidase M1 family (metallopeptidases)%3B contains a peptidase M1 domain including a zinc-binding site
chr1	3845549	3846750	+	DDB_G0270996	DDB_G0270996	NA
chr1	3847028	3848476	+	DDB_G0269910	DDB_G0269910	NA
chr1	3848909	3851073	-	DDB_G0269912	redB	catalyzes the reaction NADPH %2B n oxidized hemoprotein %3D NADP(%2B) %2B n reduced hemoprotein%3B similar to the %3Ci%3EH. sapiens %3C%2Fi%3E POR protein that is defect in adrenal hyperplasia variant type (AHV)%2C a syndrome with disordered steroidogenesis
chr1	3852049	3853851	-	DDB_G0269914	tpp1	ortholog of CLN2%2FTPP1%3B contains a predicted signal peptide%2C and a peptidase S8%2FS53 domain%3B enriched in prespore cells
chr1	3855247	3857504	+	DDB_G0269916	atp5b	beta subunit of the enzymatic component of the mitochondrial F1 ATPase complex
chr1	3858015	3858099	-	DDB_G0295499	sno3	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr1	3859398	3861680	+	DDB_G0270688	mpl2	highly similar to neighboring gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269918%22%3E%3Ci%3Empl1%3C%2Fi%3E%3C%2Fa%3E
chr1	3862624	3865313	+	DDB_G0269918	mpl1	negatively regulates the phosphorylation state of Erk2%3B expressed weakly in vegetative cells and maximally at aggregation%3B highly similar to neighboring gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270688%22%3E%3Ci%3Empl2%3C%2Fi%3E%3C%2Fa%3E
chr1	3865846	3865917	+	DDB_G0294739	tRNA-Asp-GUC-2	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	3865926	3866632	-	DDB_G0270998	DDB_G0270998_ps	putative pseudogene%3B fragment%2C similar to the large family of EGF domain-containing proteins%3B including %3Ca href%3D%22%2Fgene%2FDDB_G0272901%22%3EDDB_G0272901%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272592%22%3EDDB_G0272592%3C%2Fa%3E
chr1	3868370	3870952	+	DDB_G0269920	DDB_G0269920	NA
chr1	3871046	3874707	-	DDB_G0269922	xrn2	ortholog of H. sapiens XRN2 and S. cerevisiae RAT1 (Ribonucleic Acid Trafficking 1) involved in RNA metabolism
chr1	3875953	3879788	+	DDB_G0269924	vps18	ortholog of VPS18
chr1	3880004	3882178	-	DDB_G0269926	DDB_G0269926	putative ortholog of human RBM25
chr1	3883017	3883583	-	DDB_G0270690	DDB_G0270690	NA
chr1	3884502	3885310	-	DDB_G0269928	DDB_G0269928	contains a predicted signal peptide%3B similar to D. purpureum protein
chr1	3886301	3886597	+	DDB_G0269930	DDB_G0269930	NA
chr1	3887599	3890811	-	DDB_G0270692	DDB_G0270692	contains 6 ankyrin repeats%3B contains one VPS9 (vacuolar sorting protein 9) domain%3B similar to D. purpureum protein
chr1	3892076	3893050	+	DDB_G0269102	arcD	20 kDa component of the Dictyostelium Arp2%2FArp3 complex
chr1	3893359	3895841	-	DDB_G0269932	uap56	conserved splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint%3B the human ortholog (BAT1) forms a homodimer and interacts directly with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0286395%22%3E%3Ci%3Eu2af2%3C%2Fi%3E%3C%2Fa%3E
chr1	3897216	3903350	+	DDB_G0269934	DDB_G0269934	NA
chr1	3903678	3904826	+	DDB_G0269936	DDB_G0269936	NA
chr1	3904926	3906193	-	DDB_G0269938	osbB	NA
chr1	3906624	3907837	-	DDB_G0269940	osbC	similar to oxysterol binding protein%2C however%2C does not contain consensus binding site%3B expressed in pstAO cells and in upper and lower cups during culmination
chr1	3908437	3909660	-	DDB_G0270694	DDB_G0270694	belongs to the band 7 proteins%2C integral membrane proteins that ares thought to regulate cation conductance%3B stomatin is an erythrocyte membrane protein%3B contains one predicted transmembrane domain
chr1	3911017	3912100	+	DDB_G0269942	DDB_G0269942	belongs to the synaptobrevin family%3B ortholog of human SEC22B%3B contains a longin domain and a v-snare coiled-coil domain%3B contains 1 predicted transmembrane domain
chr1	3913001	3914017	+	DDB_G0269944	DDB_G0269944	NA
chr1	3914310	3915463	+	DDB_G0295677	mpdu1	contains at least three transmembrane domains%3B ortholog of mannose-P-dolichol utilization defect 1 protein MPDU1
chr1	3915625	3915986	-	DDB_G0269946	DDB_G0269946	NA
chr1	3916816	3919967	+	DDB_G0269948	tnpo	homolog of H. sapiens TNPO1%2F2 and S. cervisiae KAP104 (karyopherin 104) involved in nuclear protein import
chr1	3920593	3921886	+	DDB_G0269950	serC	catalyzes the reaction 3-phospho-hydroxypyruvate %2B L-glutamate %3C%3D%3E 2-oxoglutarate %2B 3-phospho-serine
chr1	3922020	3922814	-	DDB_G0269952	DDB_G0269952	NA
chr1	3923641	3926025	+	DDB_G0269954	DDB_G0269954	NA
chr1	3927053	3927940	-	DDB_G0269956	DDB_G0269956_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	3928023	3928095	-	DDB_G0294771	tRNA-Val-CAC-1	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr1	3929456	3929821	-	DDB_G0269958	DDB_G0269958	NA
chr1	3932800	3933662	+	DDB_G0269960	DDB_G0269960	NA
chr1	3933879	3936245	-	DDB_G0269962	DDB_G0269962	NA
chr1	3937103	3937960	+	DDB_G0269118	cxeA	NA
chr1	3938864	3940930	+	DDB_G0269964	DDB_G0269964	NA
chr1	3941617	3944019	+	DDB_G0269966	ddx1	ortholog of ATP-dependent RNA helicase DDX1%3B contains an SPRY domain%2C which is of unknown function
chr1	3944438	3944996	+	DDB_G0270698	cniA	similar to human CNIH%2C S. pombe erv14%3B human and Drosophila cornichon act in the selective transport and maturation of TGFalpha family proteins%3B contains 3 predicted transmembrane domains
chr1	3945381	3946280	-	DDB_G0269968	DDB_G0269968	similar to human ARMC1%3B contains an ARM repeat%3B ARM-repeat proteins are involved in various processes%2C including intracellular signalling and cytoskeletal regulation
chr1	3946896	3947753	-	DDB_G0269970	DDB_G0269970	NA
chr1	3949672	3950633	+	DDB_G0269138	fttB	localizes to the cell cortex%2C binds myosin II and regulates microtubule length%2C the cortical cytoskeleton and cytokinesis%3B functions in the same pathway as racE to regulate these processes
chr1	3952196	3954580	-	DDB_G0269972	sas10	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr1	3955288	3956544	+	DDB_G0269974	DDB_G0269974	NA
chr1	3956916	3959123	+	DDB_G0269976	DDB_G0269976	NA
chr1	3960032	3961552	+	DDB_G0269978	DDB_G0269978	NA
chr1	3962023	3963455	+	DDB_G0269980	drpp30	protein subunit of both the RNase P complex involved in tRNA processing and the RNase MRP complex involved in rRNA processing
chr1	3963577	3972340	-	DDB_G0271000	pks3	putative type I iterative polyketide synthase
chr1	3972852	3974733	-	DDB_G0269982	DDB_G0269982	similar to human TBC1D22B%3B S. pombe gyp1
chr1	3976381	3976770	-	DDB_G0269984	DDB_G0269984	NA
chr1	3977474	3979864	+	DDB_G0269986	DDB_G0269986	NA
chr1	3979902	3981306	-	DDB_G0294597	DDB_G0294597	NA
chr1	3981529	3983657	-	DDB_G0271002	DDB_G0271002	NA
chr1	3983950	3984625	-	DDB_G0350235	DDB_G0350235	NA
chr1	3985001	3985504	+	DDB_G0269988	DDB_G0269988	NA
chr1	3986134	3987976	+	DDB_G0269990	tbcE	NA
chr1	3988412	3989286	+	DDB_G0269992	DDB_G0269992	NA
chr1	3989908	3990396	-	DDB_G0269230	fpaA	component of the SCF ubiquitin ligase complex%3B the fpaA gene encodes a protein almost identical to that of fpaB%2C differing in one amino acid only%3B series of glycosylation reactions attaches a pentasaccharide chain to HyPro143
chr1	3990838	3992071	+	DDB_G0269994	DDB_G0269994	contains a highly conserved DDRGK motif the function of which is unknown
chr1	3992422	3995058	+	DDB_G0269996	rnf10	putative ortholog of mammalian RNF10
chr1	3995432	3998774	+	DDB_G0269998	DDB_G0269998	NA
chr1	3999184	4000647	+	DDB_G0270000	DDB_G0270000	NA
chr1	4001179	4002462	+	DDB_G0270002	DDB_G0270002	NA
chr1	4002803	4005323	+	DDB_G0270700	DDB_G0270700	contains a predicted signal sequence and a putative C-terminal transmembrane domain%3B contains 7 calcium-binding EGF domains
chr1	4005997	4009391	-	DDB_G0271006	DDB_G0271006_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr1	4009415	4009497	-	DDB_G0294769	tRNA-Tyr-GUA-3	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4009790	4010233	-	DDB_G0347333	DDB_G0347333	NA
chr1	4011450	4011893	-	DDB_G0270004	DDB_G0270004	NA
chr1	4013407	4013849	-	DDB_G0271008	DDB_G0271008_ps	putative pseudogene%3B similar to a %3Ci%3ED. discoideum%3C%2Fi%3E gene family%2C including the just upstream %3Ca href%3D%22%2Fgene%2FDDB_G0270004%22%3EDDB_G0270004%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0347333%22%3EDDB_G0347333%3C%2Fa%3E
chr1	4014521	4015187	+	DDB_G0271010	DDB_G0271010	NA
chr1	4015409	4017699	-	DDB_G0269152	mekA	STE Ser%2FThr protein kinase family%2C mitogen-activated protein kinase kinase%3B involved in chemotaxis and early development%2C phosphorylates the MAP kinase Erk1 (erkA)%2C is sumoyalated by sumo and ubiquinated by mip1
chr1	4018580	4021604	-	DDB_G0270006	jcdI	similar to the human JMJD6%2C which is required for organ differentiation during embryogenesis
chr1	4022273	4022909	+	DDB_G0270008	DDB_G0270008	NA
chr1	4023401	4023804	+	DDB_G0270010	DDB_G0270010	NA
chr1	4024276	4024998	+	DDB_G0270012	DDB_G0270012	NA
chr1	4026325	4027243	+	DDB_G0270014	DDB_G0270014	NA
chr1	4028749	4029268	+	DDB_G0269170	pmpA	NA
chr1	4029381	4030378	-	DDB_G0270016	DDB_G0270016	NA
chr1	4030543	4031583	-	DDB_G0270018	DDB_G0270018	NA
chr1	4032294	4034133	+	DDB_G0270020	sf3a3	subunit of the splicing factor SF3A required for spliceosome assembly%3B contains PRP9 domain characteristic of splicing factor 3A%2C subunit 3%3B expressed in pstO cells
chr1	4034417	4038553	+	DDB_G0270704	DDB_G0270704_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0268352%22%3EDDB_G0268352%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283993%22%3EDDB_G0283993%3C%2Fa%3E
chr1	4038698	4038959	-	DDB_G0295501	rnu2g	component of the spliceosome involved in pre-mRNA splicing
chr1	4039201	4040822	-	DDB_G0270706	DDB_G0270706_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes  %3Ca href%3D%22%2Fgene%2FDDB_G0270958%22%3EDDB_G0270958%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270644%22%3EDDB_G0270644%3C%2Fa%3E
chr1	4041315	4042649	+	DDB_G0270022	DDB_G0270022	some members of this family have guanine nucleotide exchange activity
chr1	4042887	4045665	-	DDB_G0270024	mgp2	involved in the regulation of filopodium formation and the contractile vacuole network
chr1	4047424	4051387	+	DDB_G0269252	gefE	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form
chr1	4051948	4052745	+	DDB_G0270026	DDB_G0270026	NA
chr1	4053112	4054599	+	DDB_G0270028	DDB_G0270028	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr1	4054671	4055435	-	DDB_G0348427	DDB_G0348427_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0270090%22%3EDDB_G0270090%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270092%22%3EDDB_G0270092%3C%2Fa%3E 
chr1	4055932	4057974	-	DDB_G0348428	DDB_G0348428	NA
chr1	4058777	4059949	+	DDB_G0270030	DDB_G0270030	NA
chr1	4060239	4061396	+	DDB_G0270032	DDB_G0270032	NA
chr1	4062615	4066228	-	DDB_G0270708	DDB_G0270708	contains a signal peptide and a putative C-terminal transmembrane domain 
chr1	4066936	4067804	+	DDB_G0270034	DDB_G0270034	NA
chr1	4068160	4069244	+	DDB_G0270036	ppp2r4	ortholog of the human PPP2R4 (PTPA) that stimulates the phosphotyrosyl phosphatase activity of PP2A in the presence of ATP and Mg(2%2B) in vitro
chr1	4072747	4074515	+	DDB_G0269142	hmgA	NA
chr1	4074913	4075404	-	DDB_G0270038	DDB_G0270038	NA
chr1	4075572	4079519	-	DDB_G0270040	DDB_G0270040	NA
chr1	4079745	4080356	-	DDB_G0270710	DDB_G0270710	NA
chr1	4082408	4089294	-	DDB_G0270042	ascc3l	putative RNA helicase involved in the second step of RNA splicing%3B ortholog of human ASCC3L1 and yeast BRR2
chr1	4089972	4092037	+	DDB_G0271014	DDB_G0271014	NA
chr1	4092193	4093572	-	DDB_G0270044	DDB_G0270044	NA
chr1	4094301	4096106	+	DDB_G0270046	DDB_G0270046	NA
chr1	4096586	4097519	+	DDB_G0270714	DDB_G0270714_ps	putative pseudogene%3B similar to a family of genes including %3Ca href%3D%22%2Fgene%2FDDB_G0293542%22%3EDDB_G0293542%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0282495%22%3EDDB_G0282495%3C%2Fa%3E
chr1	4098007	4102857	+	DDB_G0270718	DDB_G0270718	contains a predicted signal peptide
chr1	4103221	4104786	+	DDB_G0270048	DDB_G0270048	NA
chr1	4105655	4106522	+	DDB_G0270050	DDB_G0270050	NA
chr1	4106977	4111104	-	DDB_G0270052	DDB_G0270052	NA
chr1	4111305	4112469	+	DDB_G0270054	DDB_G0270054	similar to Homo sapiens activated RNA polymerase II transcriptional coactivator p15 (SwissProt P53999)
chr1	4112718	4117547	-	DDB_G0271016	DDB_G0271016	NA
chr1	4119220	4122363	-	DDB_G0271018	DDB_G0271018_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	4122654	4123988	-	DDB_G0271020	DDB_G0271020_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	4125226	4125298	+	DDB_G0294741	tRNA-Ile-AAU-1	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4125800	4127359	+	DDB_G0270720	DDB_G0270720	NA
chr1	4127506	4130007	-	DDB_G0270722	DDB_G0270722	NA
chr1	4130694	4135261	-	DDB_G0270056	DDB_G0270056	NA
chr1	4136186	4138233	+	DDB_G0271022	adcC	contains a C2 domain%2C Ca2%2B-dependent membrane-targeting module
chr1	4138891	4141933	+	DDB_G0271024	DDB_G0271024	NA
chr1	4143232	4147175	+	DDB_G0270058	DDB_G0270058	NA
chr1	4148273	4152208	+	DDB_G0270060	DDB_G0270060	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293762%22%3E%3Ci%3EDDB_G0293762%3C%2Fi%3E%3C%2Fa%3E
chr1	4152838	4157625	+	DDB_G0270062	DDB_G0270062	NA
chr1	4157920	4158806	-	DDB_G0271026	DDB_G0271026_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr1	4158870	4158942	-	DDB_G0294767	tRNA-Lys-UUU-6	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4159771	4160625	+	DDB_G0270064	DDB_G0270064_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	4160763	4164087	+	DDB_G0271028	DDB_G0271028_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	4163571	4163643	-	DDB_G0294765	tRNA-Ile-AAU-4	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4165016	4171458	-	DDB_G0270066	DDB_G0270066	NA
chr1	4171732	4172343	-	DDB_G0270724	DDB_G0270724_ps	putative pseudogene%3B fragment%2C similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0278875%22%3EdduD%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0269850%22%3EDDB_G0269850%3C%2Fa%3E
chr1	4173872	4175149	+	DDB_G0269164	egeB	highly similar to EgeA%2C required for aggregation
chr1	4175523	4179514	+	DDB_G0270068	DDB_G0270068	NA
chr1	4180324	4181863	+	DDB_G0270070	DDB_G0270070	contains two PLDc domains
chr1	4182087	4183901	-	DDB_G0270072	DDB_G0270072	contains two coiled-coil domains %3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E There is a chance that DDB_G0270072 codes for an SMC protein. The blast homology to Ciona XCAP-E is weak%2C but when the predicted XCAP-E protein is compared with DDB_G0270072 by Blast2Sequences%2C multiple regions of homology are found%2C and the overall E-value is 0%2C001. The strongest homology is in the N-terminus%2C where SMC proteins are generally strongly conserved. SMC proteins contain two prominent coiled-coil domains (separated by a hinge region)%3B according to the Dictybase curators%2C these regions are present in DDB_G0270072. SMC proteins are involved in sister chromosome cohesion and mitotic chromosome condensation. Most genes with functions in cell cycle progression are overexpressed in a strain lacking the Dicty Rb ortholog rblA. The Dicty SMC genes are highly overexpressed in this strain(10-15-fold) DDB_G0270072 is overexpressed 23-fold (p%3C4e-28)%2C a really exceptional value. %3Ci%3EHarry MacWilliams%2C May 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0270072%22%3E There is more information on the wiki page%3C%2Fa%3E
chr1	4185581	4185676	-	DDB_G0294763	tRNA-Ala-UGC-1	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4187072	4188735	-	DDB_G0270074	DDB_G0270074	belongs to the glycoside hydrolase 5 (cellulase) family 5%3B contains a predicted signal sequence
chr1	4189203	4189916	-	DDB_G0270076	DDB_G0270076	NA
chr1	4191196	4191909	-	DDB_G0270078	DDB_G0270078	NA
chr1	4192479	4192823	-	DDB_G0270080	DDB_G0270080	NA
chr1	4193386	4194108	+	DDB_G0270084	DDB_G0270084_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0270090%22%3EDDB_G0270090%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270092%22%3EDDB_G0270092%3C%2Fa%3E
chr1	4194168	4194846	-	DDB_G0270086	DDB_G0270086	similar to bacterial outer membrane lipoprotein Blc%3B lipocalins are involved in the binding and transport of small molecules such as lipids%2C steroid hormones%2C bilins%2C and retinoids
chr1	4195432	4197111	-	DDB_G0270088	DDB_G0270088	NA
chr1	4198052	4198825	+	DDB_G0270090	DDB_G0270090	NA
chr1	4199147	4199917	+	DDB_G0270092	DDB_G0270092	NA
chr1	4200105	4200448	-	DDB_G0271030	DDB_G0271030_ps	putative pseudogene%3B fragment%2C highly similar to %3Ca href%3D%22%2Fgene%2FDDB_G0272877%22%3EDDB_G0272877%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0270088%22%3EDDB_G0270088%3C%2Fa%3E
chr1	4201373	4201444	+	DDB_G0294743	tRNA-Asp-GUC-3	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis 
chr1	4201625	4202439	-	DDB_G0347202	DDB_G0347202	NA
chr1	4203953	4205248	+	DDB_G0270094	DDB_G0270094_ps	putative pseudogene%3B highly similar to %3Ca href%3D%22%2Fgene%2FDDB_G0272877%22%3EDDB_G0272877%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0270088%22%3EDDB_G0270088%3C%2Fa%3E
chr1	4205387	4207964	-	DDB_G0270096	DDB_G0270096	NA
chr1	4208288	4210353	-	DDB_G0270098	sqstm1	similar to the conserved ubiquitin-binding protein p62%2FSQSTM1%3B in %3Ci%3EDictyostelium%3C%2Fi%3E found in large ubiquitinated protein aggregates present in vmp1- and atg1- autophagy mutants
chr1	4212241	4214067	+	DDB_G0270100	DDB_G0270100	NA
chr1	4214694	4214765	+	DDB_G0294745	tRNA-Thr-AGU-10	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4216280	4219039	+	DDB_G0270726	uduC	underexpressed in %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants%3B upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr1	4222376	4224477	-	DDB_G0270102	mkcF	similar to Dictyostelium mkcA and mkcB%2C and other mitogen-activated protein kinases (Ste20%2FPAK family)%3B contains one SH3 (src Homology-3) domain
chr1	4225842	4227446	-	DDB_G0270104	DDB_G0270104	similar to plant and fungi NADH dehydrogenases such as S. cerevisiae NDE1 and NDE2%2C the external mitochondrial NADH dehydrogenases that catalyze the oxidation of cytosolic NADH
chr1	4228148	4232826	-	DDB_G0271032	DDB_G0271032	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr1	4234614	4235003	-	DDB_G0270728	DDB_G0270728_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0270104%22%3EDDB_G0270104%3C%2Fa%3E
chr1	4235323	4237343	-	DDB_G0270730	fslB	similar to the G-protein coupled receptors%3B contains 7 putative transmembrane domains and a potential signal sequence
chr1	4238878	4241893	-	DDB_G0270106	DDB_G0270106	NA
chr1	4243063	4243691	+	DDB_G0270108	DDB_G0270108_ps	putative pseudogene%2C almost identical to parts of the putative NADH dehydrogenase %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270104%22%3E%3Ci%3EDDB_G0270104%3C%2Fi%3E%3C%2Fa%3E
chr1	4244035	4246332	+	DDB_G0270110	dhx33	DEAD%2FDEAH box helicases are involved in various aspects of RNA metabolism
chr1	4247306	4249429	+	DDB_G0270732	DDB_G0270732	NA
chr1	4249798	4249869	-	DDB_G0294761	tRNA-Asp-GUC-5	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	4250554	4250625	-	DDB_G0294759	tRNA-Asp-GUC-4	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr1	4251451	4253061	-	DDB_G0270112	DDB_G0270112	NA
chr1	4256212	4260120	+	DDB_G0271034	DDB_G0271034	NA
chr1	4260144	4261313	-	DDB_G0270114	DDB_G0270114	NA
chr1	4262007	4263138	+	DDB_G0270116	DDB_G0270116	NA
chr1	4263564	4263758	+	DDB_G0271038	DDB_G0271038	NA
chr1	4264499	4268846	+	DDB_G0269244	atg6A	homolog of S. cerevisiae ATG6 and H. sapiens beclin (BECN1)%2C involved in autophagy and apoptosis
chr1	4269122	4270264	-	DDB_G0269238	rab11A	similar to rab11
chr1	4271883	4272478	-	DDB_G0270118	DDB_G0270118	contains a PPI_Ypi1 domain%2C which is predicted to be involved in protein phosphatase regulation
chr1	4273481	4274624	+	DDB_G0270120	sdhB	catalyzes the reaction succinate %2B ubiquinone %3D fumarate %2B ubiquinol
chr1	4274869	4276719	-	DDB_G0270734	DDB_G0270734	NA
chr1	4277085	4277826	-	DDB_G0270122	rasW	NA
chr1	4279831	4280520	-	DDB_G0270736	rasV	NA
chr1	4281896	4282537	-	DDB_G0270124	rasX	NA
chr1	4283626	4284369	-	DDB_G0270126	rasY	NA
chr1	4285180	4289651	+	DDB_G0271040	ints2	ortholog of integrator complex subunit 2%2C component of a multiprotein mediator of small nuclear RNA processing
chr1	4289930	4292995	+	DDB_G0270128	DDB_G0270128	NA
chr1	4293863	4295737	+	DDB_G0270130	DDB_G0270130	NA
chr1	4296112	4296573	+	DDB_G0270132	DDB_G0270132	NA
chr1	4297045	4297503	+	DDB_G0270134	DDB_G0270134	NA
chr1	4297732	4298097	-	DDB_G0270136	DDB_G0270136	NA
chr1	4298314	4298387	-	DDB_G0294757	tRNA-Val-AAC-4	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4299011	4299652	+	DDB_G0270138	rasU	NA
chr1	4300316	4300960	+	DDB_G0270140	rasZ	enriched in gametes
chr1	4301392	4301465	-	DDB_G0294755	tRNA-Val-AAC-3	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4302709	4303116	+	DDB_G0270144	DDB_G0270144_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0347333%22%3EDDB_G0347333%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270004%22%3EDDB_G0270004%3C%2Fa%3E
chr1	4304005	4305998	-	DDB_G0270146	DDB_G0270146	kinase domain similar to S. pombe cdc7%2C cell division control protein 7 which plays a role in cytokinesis
chr1	4307771	4308595	-	DDB_G0270738	DDB_G0270738	NA
chr1	4310650	4311005	+	DDB_G0270740	DDB_G0270740	NA
chr1	4311820	4313408	+	DDB_G0270148	cpsf4	ortholog of the human CPSF4 and yeast YTH1%2C the 30 kDa subunit of the cleavage and polyadenylation specificity factor (CPSF) complex required for 3%27 processing of mRNAs%3B human CPSF4 binds RNA polymers with a preference for poly(U)
chr1	4313687	4314966	-	DDB_G0270742	DDB_G0270742	protein with large regions of low complexity%3B conserved in Dictyostelids%2C though the low complexity regions diverge
chr1	4316335	4319082	+	DDB_G0270150	cepF	similar to the conserved ZW10 kinetochore-associated protein%2C an essential component of the mitotic checkpoint%2C but the %3Ci%3EDictyosteium%3C%2Fi%3E potein localizes exclusively to the corona of the centrosome%3B however%2C the proteins may share the function of dynein%2Fdynactin targeting in interphase
chr1	4319399	4321235	-	DDB_G0269168	vps26	ortholog of VSP26%2C a vacuolar sorting%2Ftargeting protein
chr1	4321908	4323986	-	DDB_G0270152	maspS	catalyzes the reaction ATP %2B L-aspartate %2B tRNAAsp %3D AMP %2B diphosphate %2B L-aspartyl-tRNAAsp
chr1	4327219	4328630	+	DDB_G0270154	DDB_G0270154	NA
chr1	4329080	4331994	-	DDB_G0270156	DDB_G0270156	NA
chr1	4332329	4335222	-	DDB_G0270744	DDB_G0270744	shares region of similarity with human proteins containing a Rab domain
chr1	4336075	4337602	-	DDB_G0270746	DDB_G0270746	putative ortholog of H. sapiens transducin beta-like 2 (TBL2)%2C deleted in patients with Williams-Beuren syndrome (WBS)
chr1	4337917	4338637	+	DDB_G0270158	DDB_G0270158	NA
chr1	4338908	4338981	+	DDB_G0294747	tRNA-Val-AAC-2	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4339530	4340174	+	DDB_G0270160	DDB_G0270160	NA
chr1	4340831	4344152	+	DDB_G0271042	DDB_G0271042	NA
chr1	4345093	4346771	+	DDB_G0270162	allB2	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B allantoin %3C%3D%3E allantoate%3B expressed in upper cup cells during culmination
chr1	4346844	4349738	-	DDB_G0271044	DDB_G0271044	contains Sec23%2FSec24 zinc finger%2C trunk%2C and helical domains%3B yeast Sec23%2FSec24 is a component of COPII (coat protein complex II) involved in ER to Golgi transport
chr1	4350714	4350986	+	DDB_G0270164	DDB_G0270164	NA
chr1	4352624	4352878	+	DDB_G0270166	DDB_G0270166	NA
chr1	4356679	4358223	+	DDB_G0270750	DDB_G0270750	contains six kelch repeats%2C which are known to be involved in various biological processes
chr1	4358663	4359839	+	DDB_G0270168	DDB_G0270168	NA
chr1	4360881	4366105	+	DDB_G0270170	DDB_G0270170	atypical protein kinase%2C GTE group%3B weakly simlar to A. thaliana bromodomain-containing protein (GenBank NP_201138)
chr1	4366498	4367403	-	DDB_G0270172	DDB_G0270172	NA
chr1	4368158	4368757	+	DDB_G0270174	aprt	catalyzes the reaction AMP %2B pyrophosphate %3C%3D%3E PRPP %2B adenine in nucleoside salvage pathways
chr1	4369737	4374066	+	DDB_G0270176	DDB_G0270176	the amino terminus contains leucine-rich repeats%2C and the carboxyl terminus a protein phosphatase 2C domain%2C a serine%2Fthreonine specific protein phosphatase with broad substrate specificity and dependent on divalent cations (mainly manganese and magnesium) for its activity
chr1	4375331	4375388	-	DDB_G0295503	r30	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr1	4375992	4377095	-	DDB_G0270178	wdr85	NA
chr1	4377432	4377910	+	DDB_G0270180	DDB_G0270180	NA
chr1	4377987	4379075	-	DDB_G0270182	DDB_G0270182	NA
chr1	4379266	4380433	-	DDB_G0270184	ger	catalyzes the reaction GDP-L-fucose %2B NADP%2B %3D GDP-4-dehydro-6-deoxy-D-mannose %2B NADPH %2B H%2B
chr1	4381272	4381856	+	DDB_G0270186	DDB_G0270186	putative copper transporter%2C contains 3 predicted transmembrane domains
chr1	4382128	4383766	+	DDB_G0270188	psmD6	NA
chr1	4384621	4386448	-	DDB_G0270190	DDB_G0270190	similar to bacterial endo-1%2C4-beta-glucanase%3B expressed in pstAO cells
chr1	4389263	4390889	+	DDB_G0270192	DDB_G0270192	conserved from bacteria to plants to alveolata%3B contains 10 predicted transmembrane domains
chr1	4391158	4391944	+	DDB_G0270194	DDB_G0270194	conserved protein
chr1	4392160	4393069	+	DDB_G0270752	DDB_G0270752	NA
chr1	4393614	4395336	+	DDB_G0270196	DDB_G0270196	similar to the mitochondrial import inner membrane translocase subunit TIM50
chr1	4395945	4396774	+	DDB_G0270198	hcpC	similar to HP1 (heterochromatin protein 1)%3B does not seem to be expressed
chr1	4397167	4399472	-	DDB_G0270200	DDB_G0270200	NA
chr1	4400104	4400817	+	DDB_G0270202	DDB_G0270202	NA
chr1	4401703	4403287	+	DDB_G0270204	crtp3	similar to Plasmodium falciparum CRT%2C which confers resistance to chloroquine%3B contains 10 predicted transmembrane domains
chr1	4404424	4408096	+	DDB_G0270206	DDB_G0270206	NA
chr1	4410084	4412006	-	DDB_G0269144	hspB	NA
chr1	4413499	4414682	-	DDB_G0270208	DDB_G0270208	NA
chr1	4415136	4415868	-	DDB_G0270210	cbpJ	Ca2%2B-binding protein with 4 putative EF-hands%3B belongs to the frequenins%2C a family of myristoyl-switch calcium-binding proteins
chr1	4416314	4417227	-	DDB_G0270212	DDB_G0270212	similar to discoidin I%3B almost identical to its downstream gene DD7-1
chr1	4418564	4419469	-	DDB_G0270214	DD7-1	similar to discoidin I%3B involved in O-glycosylation as identified by mRNA differential display%3B almost identical to its upstream gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270212%22%3E%3Ci%3EDDB_G0270212%3C%2Fi%3E%3C%2Fa%3E
chr1	4420069	4423204	-	DDB_G0270216	DDB_G0270216	NA
chr1	4423807	4426401	+	DDB_G0270754	vps16	NA
chr1	4429657	4431380	+	DDB_G0270218	glkA	putative protein serine%2Fthreonine kinase%2C GSK family%3B member of the CMGC kinase group%3B similar to Drosophila shaggy and other glycogen synthase kinases
chr1	4432689	4435367	+	DDB_G0270220	DDB_G0270220	NA
chr1	4435722	4436301	-	DDB_G0270222	DDB_G0270222	NA
chr1	4437084	4440698	+	DDB_G0270224	DDB_G0270224	NA
chr1	4441377	4441559	+	DDB_G0270226	DDB_G0270226	NA
chr1	4442110	4443725	+	DDB_G0270228	gtpbp3	ortholog of the mammalian GTPBP3 and %3Ci%3ES. cerevisiae%3C%2Fi%3E MSS1%2C GTPases responsible for the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs
chr1	4444375	4444636	+	DDB_G0271046	DDB_G0271046_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0292518%22%3EDDB_G0292518%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0280467%22%3EDDB_G0280467%3C%2Fa%3E
chr1	4445249	4446106	+	DDB_G0270230	utp11	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr1	4446395	4449415	-	DDB_G0270756	gtaG	has 18 amino acids between the two CX2C motifs
chr1	4456371	4457089	+	DDB_G0270758	DDB_G0270758	NA
chr1	4457457	4459763	+	DDB_G0270232	DDB_G0270232	NA
chr1	4460065	4463095	-	DDB_G0270760	DDB_G0270760	similar to D. purpureum protein
chr1	4466006	4466164	-	DDB_G0270234	DDB_G0270234	NA
chr1	4467278	4472517	+	DDB_G0270762	fimD	contains 4 calponin homology (CH) domains%3B two CH domains constitute one actin binding domain
chr1	4474318	4474602	+	DDB_G0270236	DDB_G0270236	NA
chr1	4474835	4479049	-	DDB_G0270238	DDB_G0270238	NA
chr1	4479608	4480480	-	DDB_G0271050	magA	hydrolyses alkylated adenine residues on DNA%2C releasing 3-methyladenine
chr1	4481557	4481909	+	DDB_G0270240	DDB_G0270240	NA
chr1	4483000	4484724	+	DDB_G0270764	myh	mutY homolog%3B ortholog of the conserved A%2FG-specific adenine DNA glycosylase MUTYH%2C which removes misincorporated adenine residues opposite template 8-oxoguanine during DNA replication
chr1	4484790	4485548	-	DDB_G0270242	DDB_G0270242	NA
chr1	4485669	4486508	+	DDB_G0270244	DDB_G0270244	NA
chr1	4486597	4491085	-	DDB_G0269206	abcG21	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr1	4493232	4498057	-	DDB_G0269208	abcG19	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr1	4499254	4502247	+	DDB_G0270766	DDB_G0270766	NA
chr1	4502537	4512340	-	DDB_G0271052	snf2b	SNF2 family protein%2C similar to human SMARCA4%3B putative regulator of chromatin
chr1	4514326	4516297	-	DDB_G0270246	DDB_G0270246	NA
chr1	4516591	4517262	+	DDB_G0270248	aplR	NA
chr1	4517624	4519199	+	DDB_G0270250	DDB_G0270250	NA
chr1	4519307	4521349	-	DDB_G0270252	DDB_G0270252	NA
chr1	4521755	4522105	+	DDB_G0270254	DDB_G0270254	NA
chr1	4522306	4522903	-	DDB_G0270256	DDB_G0270256	NA
chr1	4523481	4524638	-	DDB_G0270258	DDB_G0270258	NA
chr1	4527247	4527672	+	DDB_G0270260	nhp6	similar to S. cerevisiae nonhistone chromosomal protein 6A and B (NCP6A and NCP6B) and mammalian HMGB2%3B contains a single HMG1%2F2 box
chr1	4528758	4529451	+	DDB_G0270262	DDB_G0270262	NA
chr1	4529920	4531250	+	DDB_G0269224	fszB	nuclear gene for mitochondrial product
chr1	4531797	4533209	+	DDB_G0270264	metap2	catalyzes the release of N-terminal amino acids%2C preferentially methionine%2C from peptides and arylamides
chr1	4534439	4534675	+	DDB_G0270768	DDB_G0270768	NA
chr1	4534905	4537648	-	DDB_G0270266	DDB_G0270266	NA
chr1	4540670	4542577	+	DDB_G0270268	DDB_G0270268	NA
chr1	4542640	4543788	-	DDB_G0270270	gpsn2	very similar to human GPSN2%3B contains a 3-oxo-5-alpha-steroid 4-dehydrogenase%2C C-terminal domain and 4 putative transmembrane domains
chr1	4544769	4548249	+	DDB_G0270272	uae1	NA
chr1	4549776	4551575	-	DDB_G0270770	DDB_G0270770_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr1	4551714	4551786	-	DDB_G0294753	tRNA-Ile-AAU-3	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4551821	4552286	+	DDB_G0270274	DDB_G0270274_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr1	4552978	4553462	-	DDB_G0270276	DDB_G0270276	NA
chr1	4554019	4556699	-	DDB_G0269100	abpC	120 kDa F-actin binding protein also often called gelation factor or filamin%3B involved in actin cytoskeleton organization%2C motility%2C and development%3B enriched in prestalk cells
chr1	4556824	4557738	-	DDB_G0270772	DDB_G0270772	NA
chr1	4558267	4561757	+	DDB_G0270278	DDB_G0270278	NA
chr1	4562415	4562487	-	DDB_G0294751	tRNA-Ile-AAU-2	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4562741	4564611	-	DDB_G0270834	sgmA	hydrolyzes the phosphodiester bond in sphingomyelin to form ceramide
chr1	4565256	4567067	-	DDB_G0271054	DDB_G0271054	contains one SMAD%2FFHA domain%3B contains one coiled-coil domain
chr1	4567595	4567904	+	DDB_G0270280	DDB_G0270280	NA
chr1	4568604	4570745	+	DDB_G0271056	DDB_G0271056	NA
chr1	4570908	4575494	-	DDB_G0271058	vilC	belongs to the villin%2Fgelsolin family%3B contains 5 gelsolin-like repeats and one villin headpiece domain
chr1	4576953	4578426	-	DDB_G0270282	DDB_G0270282	NA
chr1	4579488	4580763	+	DDB_G0270284	DDB_G0270284	contains an N-terminal DOMON domain as it occurs in dopamine beta-monooxygenases%3B the %3Ci%3EDictyostelium%3C%2Fi%3E protein is followed by a cytochrome b561 domain%2C which contains 5 putative transmembrane regions%3B in addition%2C the protein contains a putative signal peptide
chr1	4581402	4583474	+	DDB_G0271060	DDB_G0271060	NA
chr1	4586186	4587098	+	DDB_G0295695	DDB_G0295695	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein similar to bacterial proteins%3B contains a predicted signal peptide
chr1	4587614	4590316	+	DDB_G0271062	DDB_G0271062	conserved hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E protein containing two FNIP repeats
chr1	4590927	4592864	+	DDB_G0270286	DDB_G0270286	NA
chr1	4593105	4593521	-	DDB_G0270288	DDB_G0270288	NA
chr1	4594432	4594848	-	DDB_G0270290	DDB_G0270290	NA
chr1	4595762	4596136	-	DDB_G0270292	DDB_G0270292	NA
chr1	4597029	4597445	-	DDB_G0270294	DDB_G0270294	NA
chr1	4598954	4600454	+	DDB_G0270296	dcd1A	wealky similar to acid ceramidase%2C which catalyzes the reaction N-acylsphingoside %2B H%3Csub%3E2%3C%2Fsub%3EO %3D a carboxylate %2B sphingosine
chr1	4600795	4602080	+	DDB_G0270298	pctA	involved in sphingomyelin degradation pathway
chr1	4602557	4603687	+	DDB_G0269234	act8	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)  
chr1	4604758	4605654	-	DDB_G0270300	DDB_G0270300	NA
chr1	4605944	4606819	-	DDB_G0270302	DDB_G0270302	NA
chr1	4607306	4608218	-	DDB_G0270304	DDB_G0270304	NA
chr1	4610085	4611533	+	DDB_G0270306	DDB_G0270306	similar to the cudA transcriptional regulator
chr1	4611669	4613378	-	DDB_G0270308	DDB_G0270308	NA
chr1	4614754	4615947	+	DDB_G0270310	DDB_G0270310	NA
chr1	4616748	4618103	+	DDB_G0270312	DDB_G0270312	members of this family are membrane proteins involved in long chain fatty acid elongation systems that produce 26-carbon precursors for ceramide and sphingolipid synthesis%3B contains 7 putative transmembrane domains
chr1	4618383	4619679	-	DDB_G0271066	DDB_G0271066	ortholog of human ELOVL4%3B members of this family are membrane proteins involved in long chain fatty acid elongation systems that produce 26-carbon precursors for ceramide and sphingolipid synthesis%3B contains 6 putative transmembrane domains
chr1	4620271	4621128	+	DDB_G0270314	crip	ortholog of human CRIP1%3B contains 1 zinc-binding LIM domain%3B LIM domains are found in proteins with differing functions%2C including gene expression%2C and cytoskeleton organisation and development
chr1	4621793	4627393	-	DDB_G0270774	DDB_G0270774	NA
chr1	4628419	4629156	-	DDB_G0270316	rpsA	40S ribosomal protein SA (p40) homolog%3B belongs to the ribosomal protein S2P family%2C contains ribosomal protein S2 domain
chr1	4629764	4632502	-	DDB_G0269162	DDB_G0269162	shares a short region of similarity with autophagy related protein Atg13
chr1	4633487	4634149	+	DDB_G0271068	iliC	induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection%3B similar to D. purpureum protein
chr1	4634981	4635241	+	DDB_G0271070	DDB_G0271070	NA
chr1	4635594	4637043	+	DDB_G0271072	med27	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 27 (metazoa) or 3 (fungi)%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr1	4638217	4639569	+	DDB_G0270318	DDB_G0270318	NA
chr1	4639723	4641353	-	DDB_G0270320	nup54	similar to mammalian Nup54%2C component of the nuclear pore complex
chr1	4641717	4643879	+	DDB_G0270322	DDB_G0270322	NA
chr1	4644690	4646184	+	DDB_G0270324	DDB_G0270324	similar to N-myc downstream regulated gene 1 (NDRG1)%3B defects in NDRG1 are the cause of Charcot-Marie-Tooth disease type 4D (CMT4D)%3B also known as hereditary motor and sensory neuropathy Lom type (HMSNL)
chr1	4646538	4649118	+	DDB_G0270776	DDB_G0270776	conserved eukaryotic protein of unknown function%3B ortholog of human SPATA20  (spermatogenesis associated 20)
chr1	4649483	4652713	+	DDB_G0270326	DDB_G0270326	NA
chr1	4652829	4653941	-	DDB_G0270328	DDB_G0270328	contains 7 Dictyostelium (slime mold) repeats%3B nearly identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270368%22%3E%3Ci%3EDDB_G0270368%3C%2Fi%3E%3C%2Fa%3E
chr1	4654733	4656612	+	DDB_G0270330	DDB_G0270330	nearly identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270366%22%3E%3Ci%3EDDB_G0270366%3C%2Fi%3E%3C%2Fa%3E
chr1	4657372	4658181	+	DDB_G0271074	DDB_G0271074	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein similar to bacterial proteins%3B contains a predicted signal peptide
chr1	4659316	4660875	-	DDB_G0270778	DDB_G0270778	NA
chr1	4661712	4661874	-	DDB_G0270780	trx_ps	putative pseudogene%3B similar to D. discoideum thioredoxin genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0294447%22%3E%3Ci%3EtrxA%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0294489%22%3E%3Ci%3EtrxC%3C%2Fi%3E%3C%2Fa%3E
chr1	4662405	4666147	-	DDB_G0270336	ipo4	ortholog of importin 4%2C a nuclear transport receptor that is thought to mediate docking of the importin%2Fsubstrate complex to the nuclear pore complex
chr1	4667184	4668853	+	DDB_G0270338	hdaB	catalyzes the removal of an acetyl group from lysine
chr1	4670322	4671453	+	DDB_G0270340	rapC	NA
chr1	4671955	4673828	-	DDB_G0270342	DDB_G0270342	NA
chr1	4674130	4678854	-	DDB_G0270344	DDB_G0270344	NA
chr1	4680332	4682412	-	DDB_G0270346	mybW	contains one Myb DNA-binding domain
chr1	4683008	4683415	-	DDB_G0270348	DDB_G0270348	NA
chr1	4684536	4685855	-	DDB_G0270784	psmC1	ATPase subunit and regulatory subcomplex of the 26S proteasome%3B TAT binding protein homolog involved in growth and morphogenesis
chr1	4686330	4688375	-	DDB_G0270786	DDB_G0270786	NA
chr1	4690187	4691199	+	DDB_G0270350	DDB_G0270350_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0270352%22%3EDDB_G0270352%3C%2Fa%3E
chr1	4691410	4692188	-	DDB_G0270788	DDB_G0270788	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein similar to bacterial proteins%3B contains a predicted signal peptide
chr1	4693514	4695492	+	DDB_G0270352	DDB_G0270352	NA
chr1	4695724	4696533	-	DDB_G0269116	cmbC	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein similar to bacterial proteins%3B contains a predicted signal peptide
chr1	4697435	4699014	+	DDB_G0270354	cyp513A3	NA
chr1	4699501	4700297	+	DDB_G0270356	erg2	catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis
chr1	4701032	4702819	+	DDB_G0270358	DDB_G0270358	ortholog of mammalian ubxn7 (UBX domain-containing protein 7)%3B contains a UBX domain%2C found in ubiquitin-regulatory proteins
chr1	4703859	4704986	-	DDB_G0270790	DDB_G0270790_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr1	4705053	4707038	-	DDB_G0270792	DDB_G0270792_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr1	4707908	4708639	-	DDB_G0271076	DDB_G0271076_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr1	4709052	4709123	-	DDB_G0294749	tRNA-Thr-AGU-11	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr1	4710295	4711059	-	DDB_G0270360	bud31	a very conserved protein%2C known as G10 protein or BUD31%2C which in human is suggested to be a nuclear transcription factor%2C and in %3Ci%3ES. pombe%3C%2Fi%3E and %3Ci%3ES. cerevisiae%3C%2Fi%3E has been shown to be a splicing factor
chr1	4712273	4713103	+	DDB_G0269106	cahA	NA
chr1	4713592	4714219	+	DDB_G0270362	zfand	NA
chr1	4714774	4715046	+	DDB_G0270364	DDB_G0270364	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon%2C but a shorter second exon  
chr1	4715122	4715514	-	DDB_G0270794	DDB_G0270794	NA
chr1	4716417	4716918	+	DDB_G0270796	cmbC_ps2	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0269116%22%3E%3Ci%3EcmbC%3C%2Fi%3E%3C%2Fa%3E 
chr1	4718091	4719957	-	DDB_G0270366	DDB_G0270366	nearly identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270330%22%3E%3Ci%3EDDB_G0270330%3C%2Fi%3E%3C%2Fa%3E%3B enriched in gametes
chr1	4720670	4721782	+	DDB_G0270368	DDB_G0270368	contains 7 Dictyostelium (slime mold) repeats%3B nearly identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270328%22%3E%3Ci%3EDDB_G0270328%3C%2Fi%3E%3C%2Fa%3E%3B enriched in gametes
chr1	4721881	4723309	-	DDB_G0270372	DDB_G0270372_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0270326%22%3EDDB_G0270326%3C%2Fa%3E
chr1	4724596	4724743	+	DDB_G0270374	DDB_G0270374_ps	putative pseudogene%3B similar to a family of small D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0270376%22%3EDDB_G0270376%3C%2Fa%3E  and %3Ca href%3D%22%2Fgene%2FDDB_G0270798%22%3EDDB_G0270798%3C%2Fa%3E
chr1	4725378	4725695	+	DDB_G0270798	DDB_G0270798	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon   
chr1	4726483	4726846	+	DDB_G0270376	DDB_G0270376	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr1	4727960	4729831	+	DDB_G0270378	DDB_G0270378	similar to human TTC39C%3B matches PFAM outer membrane protein%2C IML2%2C mitochondrial%2Ftetratricopeptide repeat protein 39
chr1	4730345	4731162	-	DDB_G0270380	rpl30	protein component of the large (60S) ribosomal subunit
chr1	4732515	4733489	+	DDB_G0270382	DDB_G0270382	NA
chr1	4733677	4734627	-	DDB_G0270384	tsn	ortholog of human TSN%3B DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations%3B interacts with translin-associated protein X (TSNAX)
chr1	4734866	4735241	+	DDB_G0270800	DDB_G0270800	NA
chr1	4735593	4737533	+	DDB_G0270386	DDB_G0270386	NA
chr1	4737656	4740668	-	DDB_G0270388	DDB_G0270388	similar to a D. purpureum protein
chr1	4742507	4744747	+	DDB_G0270390	DDB_G0270390	NA
chr1	4745422	4748998	+	DDB_G0270802	DDB_G0270802	NA
chr1	4749183	4751699	+	DDB_G0270392	cpsf2	ortholog of the human CPSF2 and yeast CFT2%2C the 100 kDa subunit of the cleavage and polyadenylation specificity factor (CPSF) complex required for 3%27 processing of mRNAs
chr1	4751920	4752333	-	DDB_G0270394	DDB_G0270394	NA
chr1	4752654	4754329	+	DDB_G0270396	ddx49	ortholog of H. sapiens DDX49
chr1	4755270	4757427	-	DDB_G0269200	cplA	NA
chr1	4758927	4763559	-	DDB_G0270398	raptor	putative Raptor protein ortholog%2C a component of the TORC1 complex in yeasts with Lst8 and Tor%3B does not co-immunoprecipitate with the TORC2 complex %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Freference%2Freference.pl?refNo%3D11155%22%3E(Lee et al 2005)%3C%2Fa%3E%3B contains WD40 and HEAT repeats%2C and armadillo-like helical domains
chr1	4764421	4768313	+	DDB_G0271078	orcC	DNA replication initiation is driven by a conserved six protein complex%2C the origin recognition complex (ORC)%3B has a role in both chromosomal replication and mating type transcriptional silencing
chr1	4768681	4771055	+	DDB_G0269148	lkhA	NA
chr1	4771263	4771496	-	DDB_G0271080	DDB_G0271080	NA
chr1	4773468	4775096	-	DDB_G0270400	DDB_G0270400	NA
chr1	4775472	4775758	+	DDB_G0270804	vps13D_ps1	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0286545%22%3E%3Ci%3Evps13D%3C%2Fi%3E%3C%2Fa%3E 
chr1	4776808	4782904	-	DDB_G0269198	wimA	NA
chr1	4784022	4784931	+	DDB_G0270402	DDB_G0270402	contains a putative Like-Sm (Lsm) domain%3B possible homolog of LSM12
chr1	4785053	4791836	-	DDB_G0270404	docB	NA
chr1	4793277	4794092	-	DDB_G0269184	rzpA	possible adaptor protein
chr1	4795072	4795650	+	DDB_G0271084	DDB_G0271084	NA
chr1	4795840	4798577	-	DDB_G0270406	eIF4e3	EIF4E3 ortholog%2C the eukaryotic initiation factor 4E member 3%3B recognizes and binds the RNA cap during protein synthesis
chr1	4800145	4802005	+	DDB_G0270806	ldhd	catalyzes the reaction R)-lactate %2B 2 ferricytochrome c %3D pyruvate %2B 2 ferrocytochrome c
chr1	4802064	4805588	-	DDB_G0270808	scy2	highly similar to SCY1 family kinases%3B does not contain the consensus sequences required for kinase function%2C however%2C the SCY1 family encodes highly conserved non-canonical kinases that are believed to function
chr1	4808484	4809557	+	DDB_G0271086	DDB_G0271086	NA
chr1	4810031	4811239	+	DDB_G0270408	DDB_G0270408	NA
chr1	4811940	4818335	-	DDB_G0270410	stcB	NA
chr1	4819722	4821704	+	DDB_G0270412	DDB_G0270412	NA
chr1	4822178	4823193	+	DDB_G0270414	tmem56C	homolog of mammalian TMEM56%3B there are three genes in %3Ci%3EDictyostelium%3C%2Fi%3E: %3Ci%3Etmem56A%3C%2Fi%3E%2C %3Ci%3Etmem56B%3C%2Fi%3E%2C and %3Ci%3Etmem56C%3C%2Fi%3E%3B contains 7 putative transmembrane domains
chr1	4823455	4826412	+	DDB_G0270416	DDB_G0270416	similar to H. sapiens USP37 and USP26
chr1	4826715	4830122	-	DDB_G0269132	ecmB	composed of approx. 35 copies of a 24-amino-acid cysteine-rich repeat%3B expression is decreased in %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281381%22%3E%3Ci%3EdstA%3C%2Fi%3E%3C%2Fa%3E cells
chr1	4831688	4836353	-	DDB_G0270418	top2	controls the topological state of DNA by transient double-strand breakage and subsequent rejoining of DNA strands%3B this is predicted to be a nuclear topoisomerase II
chr1	4837019	4839376	-	DDB_G0270810	DDB_G0270810	NA
chr1	4839738	4839869	-	DDB_G0270812	DDB_G0270812	NA
chr1	4840357	4841439	-	DDB_G0270420	DDB_G0270420	NA
chr1	4842234	4844540	-	DDB_G0270422	slc4	NA
chr1	4845008	4845498	-	DDB_G0271092	H3c	component of the H2A-H2B-H3-H4 histone octamer%3B dimerizes with histone H4
chr1	4846006	4846565	-	DDB_G0270838	H3b	component of the H2A-H2B-H3-H4 histone octamer%3B dimerizes with histone H4
chr1	4847143	4848761	-	DDB_G0270814	nek2	protein serine%2Fthreonine kinase%3B homologous to human Nek2 kinase%3B involved in formation of microtubule-organizing centers (MTOCs)
chr1	4849685	4850344	+	DDB_G0270424	rpl35a	protein component of the large (60S) ribosomal subunit
chr1	4851386	4851959	+	DDB_G0270426	DDB_G0270426	NA
chr1	4852185	4852947	-	DDB_G0270428	DDB_G0270428	NA
chr1	4853471	4854871	+	DDB_G0269186	snpC	NA
chr1	4856092	4856685	-	DDB_G0270430	wipA	interacts with WASP (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293834%22%3E%3Ci%3EwasA%3C%2Fi%3E%3C%2Fa%3E) and plays a role in F-actin elongation and pseudopod formation in response to chemoattractant%3B contains an actin-binding WH2 (Wiskott Aldrich syndrome homology region 2) domain and a WH1-like central region%3B predicted to have an N-terminal signal peptide
chr1	4857327	4861922	-	DDB_G0270432	DDB_G0270432	NA
chr1	4862383	4866613	+	DDB_G0269158	npcA	one of two orthologs of NPC1 (with %3Ca href%3D%22%2Fgene%2FnpcB%22%3EnpcB%3C%2Fa%3E)%2C a Patch family protein%2C mutated in Niemann-Pick disease%2C a form of lipidosis characterized by the accumulation of unestrified cholesterol in the lysosomes%3B contains a signal peptide and 14 predicted transmembrane domains
chr1	4866950	4872568	+	DDB_G0270434	med23	ortholog of the mediator of RNA polymerase II transcription subunit 23%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr1	4873137	4875220	-	DDB_G0270436	DDB_G0270436	NA
chr1	4879000	4880597	-	DDB_G0270816	DDB_G0270816	NA
chr1	4881217	4881761	+	DDB_G0270438	DDB_G0270438	contains two predicted transmembrane domains
chr1	4882133	4882733	+	DDB_G0270440	DDB_G0270440	NA
chr1	4882826	4884472	-	DDB_G0270442	polA3	ortholog of the DNA primase large subunit of the DNA polymerase alpha-primase complex%2C required for the initiation of DNA replication
chr1	4885046	4886981	+	DDB_G0269190	tcp1	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr1	4887451	4889926	+	DDB_G0269114	numA	there are three reported numA isoforms%2C the largest 97 kDa numA2%2C the 66 kDa numA1%2C  and the smallest 43 kDA numA3%3B all isoforms contain a nuclear localization signal%2C a CaM binding domain%2C and a DEED (D%2FE repeat) domain%3B the larger numA2 contains an additional BRCT (Breast Cancer C_Terminal) domain
chr1	4890352	4894529	+	DDB_G0270444	DDB_G0270444	kinase domain similar to mitogen-activated protein kinases%3B does not contain the consensus sequences required for kinase function%3B N-terminus contains WD40 repeats
chr1	4894629	4895040	-	DDB_G0270818	sdhaf1B	NA
chr1	4895305	4897930	+	DDB_G0346831	DDB_G0346831	NA
chr1	4898040	4899887	+	DDB_G0346833	DDB_G0346833	NA
chr1	4899926	4903011	-	DDB_G0270446	DDB_G0270446	NA
chr1	4903242	4904821	+	DDB_G0270448	DDB_G0270448	NA
chr1	4904923	4906041	-	DDB_G0270450	DDB_G0270450	RRM domain similar to that of splicing factor RBM17 (RNA binding motif 17)%2C a splice factor
chr1	4906213	4908821	+	DDB_G0270452	DDB_G0270452	contains an N-terminal F-box domain
chr1	4909508	4909963	+	DDB_G0270454	DDB_G0270454	contains one ML (MD-2-related lipid recognition) domain%3B similar to fungal proteins of the NPC2 family%3B contains a predicted signal peptide
chr1	4912005	4912913	+	DDB_G0270820	DDB_G0270820_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	4913554	4914318	+	DDB_G0270822	DDB_G0270822_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr1	4916220	4916450	-	DDB_G0270456	DDB_G0270456_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr1	4916854	4919783	-	DDB_G0270824	DDB_G0270824_TE	fusion of the DNA transposon Tdd-4 (downstream of exon 2) and and thugS%2C an AT-rich low copy repetitive element (exon 1)
chr1	4921654	4922346	+	DDB_G0305569	DDB_G0305569	NA
chr2	2782	4464	-	DDB_G0294296	DDB_G0294296_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2	5771	6097	+	DDB_G0294294	DDB_G0294294	contains a single chomo domain
chr2	8123	10250	+	DDB_G0294292	DDB_G0294292	similar to S. cerevisiae Lgs1%2C a putative GTPase involved in 60S ribosomal subunit biogenesis
chr2	10462	13395	+	DDB_G0294290	DDB_G0294290	shares a short region of similarity with the nucleotide excision repair protein ERCC5%2FXPG
chr2	13927	15420	+	DDB_G0271114	DDB_G0271114	NA
chr2	16144	18303	+	DDB_G0271112	DDB_G0271112	NA
chr2	19444	19753	+	DDB_G0271110	DDB_G0271110	small Dictyostelium protein family%3B absent from other organisms
chr2	20345	22738	-	DDB_G0271096	atg7	homolog of yeast atg7
chr2	23987	24096	+	DDB_G0295505	rnu6	component of the spliceosome involved in pre-mRNA splicing
chr2	25027	25857	+	DDB_G0271118	DDB_G0271118_ps	putative pseudogene%3B bromodomain protein
chr2	28810	29948	+	DDB_G0271108	DDB_G0271108	NA
chr2	30690	32971	-	DDB_G0271120	DDB_G0271120	very similar to the mammalian glucosidase II subunit beta also known as  protein kinase C substrate 80K-H%2C which catalyzes the sequential removal of two alpha-1%2C3-linked glucose residues in the second step of N-linked oligosaccharide processing%3B also similar to yeast GTB1%3B defects in human PRKCSH are a cause of polycystic liver disease (PCLD)
chr2	33552	34772	-	DDB_G0271122	ufd1	similar to S. cerevisiae UDF1%2C together with npl4 and cdcD%2C involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation 
chr2	35093	36256	+	DDB_G0271106	sod2	ortholog of the human SOD2%2C the mitochondrial superoxide dismutase%3B belongs to the iron%2Fmanganese superoxide dismutase family
chr2	37151	39100	+	DDB_G0271124	DDB_G0271124	NA
chr2	39516	40537	+	DDB_G0271104	DDB_G0271104	NA
chr2	40824	42647	+	DDB_G0271126	plbB	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276767%22%3E%3Ci%3EplbA%3C%2Fi%3E%3C%2Fa%3E%2C which catalyzes the hydrolysis of phosphatidylcholine to glycerophosphocholine
chr2	43353	44107	-	DDB_G0271128	DDB_G0271128_ps	putative pseudogene%3B SAP DNA-binding domain protein
chr2	44348	44558	-	DDB_G0271102	DDB_G0271102	NA
chr2	45087	47409	+	DDB_G0271130	DDB_G0271130	NA
chr2	47597	49269	-	DDB_G0271100	DDB_G0271100	NA
chr2	49746	50400	-	DDB_G0271098	DDB_G0271098	NA
chr2	51145	53815	+	DDB_G0271132	DDB_G0271132	NA
chr2	54276	55313	-	DDB_G0271350	DDB_G0271350	NA
chr2	56277	57041	+	DDB_G0271354	DDB_G0271354	NA
chr2	57583	57963	+	DDB_G0271142	proC	G-actin binding protein that is located to filopodia%2C binds to VASP%2C and is involved in chemotaxis
chr2	58680	60890	-	DDB_G0271134	celA	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages
chr2	62552	65951	+	DDB_G0271348	DDB_G0271348	similar to H. sapiens USP35 and USP38
chr2	66274	67623	+	DDB_G0271346	yod1	similar to deubiquitinating enzyme
chr2	68200	69521	+	DDB_G0271344	idhA	catalyzes the reaction isocitrate %2B NAD%2B %3C%3D%3E 2-oxoglutarate %2B CO2 %2B NADH
chr2	69676	71350	-	DDB_G0271146	udkD	contains a N-terminal uridine kinase domaine domain and a C-terminal adenylate cyclase domain%2C like the UdkC protein and other plant proteins
chr2	72258	72959	+	DDB_G0271356	DDB_G0271356	contains 3 zinc-binding LIM domains%3B LIM domains are found in proteins with differing functions%2C including gene expression%2C and cytoskeleton organisation and development
chr2	73360	75578	-	DDB_G0271342	dgat1	catalyzes the reaction: acyl-CoA %2B 1%2C2-diacylglycerol %3D CoA %2B triacylglycerol%3B similar to mammalian DGAT1%3B contains 9 predicted transmembrane domains
chr2	76522	78883	+	DDB_G0271340	DDB_G0271340	catalyzes the reaction acyl-CoA %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E trans-2%2C3-dehydroacyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3B expressed in pstAB cells and in upper cup during culmination
chr2	79477	80109	+	DDB_G0271358	DDB_G0271358	NA
chr2	80918	83014	-	DDB_G0271338	taf7	TFIID subunit%2C involved in RNA polymerase II transcription initiation
chr2	83383	83859	+	DDB_G0271136	gafA	contains a GAF domain (cGMP-specific and stimulated PDEs%2C Anabaena adenylate cyclases%2C and E. coli FhlA)
chr2	84159	84710	+	DDB_G0271336	DDB_G0271336	NA
chr2	85049	86746	-	DDB_G0271360	DDB_G0271360	NA
chr2	87969	92642	+	DDB_G0271334	DDB_G0271334	contains a dilute domain%2C found at the carboxyl terminus of non-muscle myosin V
chr2	93170	93866	+	DDB_G0271332	DDB_G0271332	NA
chr2	94411	96261	-	DDB_G0271362	DDB_G0271362	NA
chr2	97475	99331	-	DDB_G0271330	DDB_G0271330	NA
chr2	100329	101055	-	DDB_G0271328	DDB_G0271328_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271414%22%3EDDB_G0271414%3C%2Fa%3E 
chr2	102030	102452	+	DDB_G0271326	DDB_G0271326	NA
chr2	104273	105468	-	DDB_G0271324	DDB_G0271324	NA
chr2	105543	106313	+	DDB_G0271364	DDB_G0271364_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0271330%22%3EDDB_G0271330%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271362%22%3EDDB_G0271362%3C%2Fa%3E
chr2	106314	106926	-	DDB_G0271322	DDB_G0271322_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271166%22%3EDDB_G0271166%3C%2Fa%3E
chr2	107780	108202	+	DDB_G0271320	DDB_G0271320	NA
chr2	111179	111790	-	DDB_G0271366	DDB_G0271366	NA
chr2	111944	113107	-	DDB_G0271368	DDB_G0271368	NA
chr2	113549	113814	-	DDB_G0271318	DDB_G0271318	NA
chr2	115000	116100	+	DDB_G0271370	DDB_G0271370	NA
chr2	117705	120704	+	DDB_G0271372	DDB_G0271372	similar to human TIF1a atypical protein kinase%3B RING and B-box zinc finger containing protein%2C kelch repeat-containing protein
chr2	120793	121653	-	DDB_G0271316	DDB_G0271316	NA
chr2	122691	124164	+	DDB_G0271314	iliH	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr2	124590	125063	-	DDB_G0271312	sf3b5	subunit of the splicing factor SF3B required for spliceosome assembly%3B belongs to the SF3b10 (splicing factor 3B 10 kDa subunit) family
chr2	125735	126918	-	DDB_G0271310	ucpA	ortholog of S. cerevisiae OAC1%2C involved in transport of oxaloacetate%2C sulfate%2C and thiosulfate across the mitochondrial membrane%3B contains two transmembrane domains 
chr2	127309	129669	+	DDB_G0271308	DDB_G0271308	NA
chr2	129822	131608	-	DDB_G0271306	nmd3	conserved NMD3 protein%2C which in S. cerevisiae is involved in the nuclear export of the large ribosomal subunit
chr2	132172	133092	+	DDB_G0271304	DDB_G0271304	NA
chr2	133239	133921	-	DDB_G0271148	rps25	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S25 homolog
chr2	135005	136400	+	DDB_G0271374	DDB_G0271374	NA
chr2	136477	138924	-	DDB_G0271302	DDB_G0271302	NA
chr2	139580	140112	+	DDB_G0271300	DDB_G0271300	NA
chr2	140424	141268	-	DDB_G0271298	rpl27	protein component of the large (60S) ribosomal subunit
chr2	141746	143828	+	DDB_G0271296	DDB_G0271296	NA
chr2	143922	144507	-	DDB_G0271294	DDB_G0271294	NA
chr2	144988	145882	+	DDB_G0271376	DDB_G0271376	NA
chr2	145979	146752	-	DDB_G0271292	DDB_G0271292	NA
chr2	147174	148936	-	DDB_G0271378	DDB_G0271378	NA
chr2	149480	150692	-	DDB_G0271290	DDB_G0271290	NA
chr2	151328	153636	-	DDB_G0295817	DDB_G0295817	NA
chr2	154060	155421	+	DDB_G0271288	DDB_G0271288	ortholog of the putative tumor suppressor candidate 4 protein (TUSC4)%3B the nitrogen permease regulator 2 (NPR2) family of regulators are involved in post-translational control of nitrogen permease
chr2	155520	158592	-	DDB_G0271286	clasp	similar to cytoplasmic linker protein (CLIP) associated protein 1 (CLASP1)
chr2	159603	160818	+	DDB_G0271380	DDB_G0271380_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0295819%22%3EDDB_G0295819%3C%2Fa%3E  and %3Ca href%3D%22%2Fgene%2FDDB_G0283103%22%3EDDB_G0283103%3C%2Fa%3E 
chr2	160979	162041	-	DDB_G0271282	csn7	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8) 
chr2	162882	164723	+	DDB_G0271280	DDB_G0271280	similar to D. purpurem protein
chr2	165859	166911	-	DDB_G0271276	DDB_G0271276_ps	putative pseudogene%2C highly similar to %3Ca href%3D%22%2Fgene%2FDDB_G0292366%22%3EDDB_G0292366%3C%2Fa%3E
chr2	168234	171456	+	DDB_G0271384	DDB_G0271384	NA
chr2	171780	172367	-	DDB_G0271274	DDB_G0271274	NA
chr2	174413	179109	-	DDB_G0271272	DDB_G0271272	similar to the human MybBP1A (Myb-binding protein 1A) that may activate or repress transcription
chr2	179519	180598	-	DDB_G0271270	DDB_G0271270	similar to mammalian predicted Zn-dependent hydrolases of the beta-lactamase fold
chr2	181275	181835	+	DDB_G0271268	DDB_G0271268	NA
chr2	182683	182892	-	DDB_G0271266	DDB_G0271266	NA
chr2	183660	185473	+	DDB_G0271264	usp14	ortholog of H. sapiens USP14 and S. cerevisiae UBP6
chr2	185586	187625	-	DDB_G0348640	DDB_G0348640_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276559%22%3EDDB_G0276559%3C%2Fa%3E
chr2	188685	188894	-	DDB_G0348639	DDB_G0348639	NA
chr2	190327	192051	+	DDB_G0271386	DDB_G0271386	NA
chr2	192510	192719	-	DDB_G0271260	DDB_G0271260	NA
chr2	193220	196196	-	DDB_G0271138	abcA8	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr2	196707	199668	+	DDB_G0271140	abcA7	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr2	199855	202858	-	DDB_G0271388	cog8	similar to COG8%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits
chr2	203789	204703	-	DDB_G0271390	DDB_G0271390_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271408%22%3EDDB_G0271408%3C%2Fa%3E  and %3Ca href%3D%22%2Fgene%2FDDB_G0271430%22%3EDDB_G0271430%3C%2Fa%3E 
chr2	205101	206734	-	DDB_G0271256	DDB_G0271256_ps	putative pseudogene%3B similar to a large gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271202%22%3EDDB_G0271202%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271408%22%3EDDB_G0271408%3C%2Fa%3E
chr2	207386	209360	-	DDB_G0271392	DDB_G0271392_ps	putative pseudogene%3B similar to a D. discoideum gene family including %3Ca href%3D%22%2Fgene%2FDDB_G0347826%22%3EDDB_G0347826%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271228%22%3EDDB_G0271228%3C%2Fa%3E
chr2	210375	211283	+	DDB_G0271254	DDB_G0271254	conserved hypothetical 278 aa Dictyostelium protein
chr2	211402	212935	-	DDB_G0271394	DDB_G0271394	NA
chr2	213313	213582	+	DDB_G0271252	DDB_G0271252	NA
chr2	213822	214686	+	DDB_G0271396	DDB_G0271396	similar to human EXOSC6 and S. pombe mtr3%2C which are components of the exosome%2C a 3%27-5%27 exoribonuclease complex involved in RNA processing
chr2	214985	216567	+	DDB_G0271250	DDB_G0271250	NA
chr2	216838	218448	-	DDB_G0271144	cnxA	Ca2%2B-binding protein with chaperone activity in the endoplasmic reticulum%3B plays a role in phagocytosis
chr2	219294	225244	+	DDB_G0271398	mon2	ortholog of MON2%3B in S. cerevisiae%2C MON2 plays a a role in endocytosis and vacuole integrity
chr2	226562	227913	+	DDB_G0271248	DDB_G0271248	NA
chr2	227992	229290	-	DDB_G0271400	dcc1	similar to human DSCC1 and S. cerevisiae DCC1%2C involved in sister chromatid cohesion establishment
chr2	229505	230482	-	DDB_G0271246	med19	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 19%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr2	230689	232323	+	DDB_G0271244	DDB_G0271244	NA
chr2	232357	234234	-	DDB_G0271242	DDB_G0271242	NA
chr2	234746	236537	+	DDB_G0271240	utp18	putative U3 snoRNP protein%3B ortholog of H. sapiens and S. cerevisiae UTP18
chr2	241165	243803	+	DDB_G0271402	DDB_G0271402	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family
chr2	244515	248096	+	DDB_G0271238	DDB_G0271238	conserved hypothetical Dictyostelium protein
chr2	248591	252181	+	DDB_G0271236	DDB_G0271236_ps	putative pseudogene%3B member of a Dictyostelium-specific gene family
chr2	252762	256367	+	DDB_G0271234	dduB	downregulated in the uninfected %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant%3B contains a predicted signal peptide and a C-terminal transmembrane domain
chr2	256636	257863	+	DDB_G0271232	DDB_G0271232_ps	putative pseudogene%2C similar to the putative extracellular matrix protein DDB_G0271722 and other family members
chr2	258017	259915	+	DDB_G0271228	DDB_G0271228	NA
chr2	260280	262361	+	DDB_G0271404	DDB_G0271404	NA
chr2	262858	264032	+	DDB_G0271226	DDB_G0271226_ps	putative pseudogene%3B similar to a larger gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0347826%22%3EDDB_G0347826%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271216%22%3EDDB_G0271216%3C%2Fa%3E
chr2	264272	265475	-	DDB_G0271224	cyp517A3_ps	putative pseudogene%3B related to the cytochrome P450 family
chr2	266225	273016	+	DDB_G0271222	pks4_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr2	274412	274774	+	DDB_G0271220	DDB_G0271220	NA
chr2	275867	279012	+	DDB_G0271218	DDB_G0271218	conserved in Dictyostelium
chr2	279448	281436	+	DDB_G0271406	DDB_G0271406	NA
chr2	282899	284827	+	DDB_G0271408	DDB_G0271408	NA
chr2	285190	287112	+	DDB_G0271216	DDB_G0271216	NA
chr2	287435	287769	-	DDB_G0271410	DDB_G0271410_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0286885%22%3EDDB_G0286885%3C%2Fa%3E
chr2	288473	290452	+	DDB_G0271214	DDB_G0271214	NA
chr2	290676	290795	-	DDB_G0271212	DDB_G0271212	NA
chr2	290849	290968	-	DDB_G0271210	DDB_G0271210	NA
chr2	293096	294096	-	DDB_G0271204	DDB_G0271204_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0286885%22%3EDDB_G0286885%3C%2Fa%3E 
chr2	294765	296618	+	DDB_G0271412	DDB_G0271412	NA
chr2	297663	299516	+	DDB_G0271202	DDB_G0271202	NA
chr2	299937	301916	-	DDB_G0347826	DDB_G0347826	NA
chr2	302268	302708	-	DDB_G0347828	DDB_G0347828	NA
chr2	303072	303319	+	DDB_G0271198	DDB_G0271198	NA
chr2	303584	304540	-	DDB_G0271414	DDB_G0271414	NA
chr2	306087	306509	+	DDB_G0271196	DDB_G0271196	NA
chr2	306767	307204	-	DDB_G0271194	DDB_G0271194_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr2	309490	311472	+	DDB_G0271418	DDB_G0271418	NA
chr2	312077	312307	-	DDB_G0271352	DDB_G0271352_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr2	314547	315689	-	DDB_G0271422	DDB_G0271422_TE	putative DNA transposon Tdd-4%3B fragment%3B refer to U57081 for full-length consensus element
chr2	317314	319126	+	DDB_G0271424	DDB_G0271424_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271228%22%3EDDB_G0271228%3C%2Fa%3E  and %3Ca href%3D%22%2Fgene%2FDDB_G0347826%22%3EDDB_G0347826%3C%2Fa%3E 
chr2	319239	319508	-	DDB_G0271192	DDB_G0271192	NA
chr2	319621	320068	+	DDB_G0271426	DDB_G0271426_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0282573%22%3EDDB_G0282573%3C%2Fa%3E 
chr2	321627	322716	-	DDB_G0271428	DDB_G0271428_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0279593%22%3EDDB_G0279593%3C%2Fa%3E 
chr2	323360	325456	+	DDB_G0271430	DDB_G0271430	NA
chr2	326565	328200	+	DDB_G0271190	DDB_G0271190_ps	putative pseudogene
chr2	328676	330047	-	DDB_G0271188	DDB_G0271188	member of a large D. discoideum gene family that seems to be more diverse and not so expanded in D. purpureum and P. pallidum
chr2	333149	333922	+	DDB_G0271186	DDB_G0271186_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0347826%22%3EDDB_G0347826%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271412%22%3EDDB_G0271412%3C%2Fa%3E
chr2	334485	336395	+	DDB_G0271434	DDB_G0271434	NA
chr2	336811	338102	-	DDB_G0271184	DDB_G0271184_ps	putative pseudogene with partial similarity to myoG
chr2	338345	339417	+	DDB_G0271180	DDB_G0271180_ps	putative pseudogene%3B similar to a large family of D. discoideum proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271434%22%3EDDB_G0271434%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271412%22%3EDDB_G0271412%3C%2Fa%3E
chr2	341330	341751	-	DDB_G0271178	DDB_G0271178	NA
chr2	343079	345782	+	DDB_G0271176	DDB_G0271176_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271462%22%3EDDB_G0271462%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E
chr2	347022	347095	-	DDB_G0295009	tRNA-Val-AAC-12	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr2	349161	349697	+	DDB_G0271172	DDB_G0271172_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr2	350196	351779	+	DDB_G0271168	DDB_G0271168_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271166%22%3EDDB_G0271166%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E
chr2	351938	354690	+	DDB_G0271166	DDB_G0271166	NA
chr2	355407	356592	+	DDB_G0271164	DDB_G0271164_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271166%22%3EDDB_G0271166%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271458%22%3EDDB_G0271458%3C%2Fa%3E
chr2	356657	357039	-	DDB_G0271162	DDB_G0271162	NA
chr2	358067	360898	+	DDB_G0271438	DDB_G0271438	NA
chr2	361149	363197	-	DDB_G0271160	DDB_G0271160	NA
chr2	365065	366281	+	DDB_G0271158	DDB_G0271158_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271458%22%3EDDB_G0271458%3C%2Fa%3E
chr2	366668	369596	-	DDB_G0271440	DDB_G0271440_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr2	370188	371153	+	DDB_G0271156	DDB_G0271156_ps	putative pseudogene%3B fragment%2C similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E
chr2	371956	372178	-	DDB_G0271444	DDB_G0271444_ps	NA
chr2	373067	373492	-	DDB_G0271154	DDB_G0271154_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr2	374110	375060	-	DDB_G0271446	DDB_G0271446_ps	putative pseudogene%3B fragment%2C similar to a large family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271418%22%3EDDB_G0271418%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271228%22%3EDDB_G0271228%3C%2Fa%3E
chr2	375288	375858	-	DDB_G0271152	DDB_G0271152	NA
chr2	376705	377284	-	DDB_G0271150	DDB_G0271150	NA
chr2	377800	378441	-	DDB_G0271448	DDB_G0271448_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	378769	379305	-	DDB_G0271450	DDB_G0271450_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	382297	384348	-	DDB_G0271452	DDB_G0271452_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	384873	385951	-	DDB_G0271454	DDB_G0271454_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	386413	386486	-	DDB_G0295007	tRNA-Val-AAC-11	transfers a valine residue to a growing polypeptide chain during protein synthesis 
chr2	386778	388706	-	DDB_G0271456	DDB_G0271456_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr2	389413	392448	+	DDB_G0271458	DDB_G0271458	NA
chr2	393193	396354	+	DDB_G0271460	DDB_G0271460	NA
chr2	396914	399967	+	DDB_G0271462	DDB_G0271462	NA
chr2	400170	401273	-	DDB_G0348674	colA_ps7	putative pseudogene%3B small fragment similar to the large colossin A gene %3Ca href%3D%22%2Fgene%2FDDB_G0279833%22%3EcolA%3C%2Fa%3E
chr2	401358	403119	+	DDB_G0271466	DDB_G0271466_ps	putative pseudogene%3B similar to a D. discoideum gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271458%22%3EDDB_G0271458%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271462%22%3EDDB_G0271462%3C%2Fa%3E
chr2	403904	406636	+	DDB_G0271468	DDB_G0271468	NA
chr2	406925	407452	-	DDB_G0271470	DDB_G0271470	NA
chr2	408255	410625	+	DDB_G0271472	DDB_G0271472	NA
chr2	411947	412344	-	DDB_G0271474	DDB_G0271474_ps	putative pseudogene%3B fragment of D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271478%22%3EDDB_G0271478%3C%2Fa%3E
chr2	413395	415679	+	DDB_G0271476	DDB_G0271476	NA
chr2	415978	417927	-	DDB_G0271478	DDB_G0271478	NA
chr2	418580	422227	+	DDB_G0271480	DDB_G0271480	NA
chr2	422622	426584	+	DDB_G0271482	DDB_G0271482	NA
chr2	427690	429466	+	DDB_G0271484	DDB_G0271484	NA
chr2	430036	430353	+	DDB_G0271486	DDB_G0271486	NA
chr2	430599	432413	-	DDB_G0271488	vta1	similar to human and yeast VTA1 involved in endosomal protein sorting
chr2	432789	434039	-	DDB_G0271490	melA	conserved protein%3B alpha-galactosidase (melibiase) catalyses the hydrolysis of melibiose into galactose and glucose
chr2	435997	438658	+	DDB_G0294096	clcA	CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles%3B they assemble to form homo-dimers %3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with clc%2C also known as clcA%2C encoding the clathrin light chain
chr2	440350	441973	+	DDB_G0294094	lrrA	putative ortholog of H. sapiens SHOC2%2C also known as  Ras-binding protein Sur-8
chr2	442827	445598	+	DDB_G0271664	DDB_G0271664	similar to mammalian XPR1%2C which may confer susceptibility to infection with murine leukaemia viruses%3B also similar to yeast SYG1%2C a G-protein associated signal transduction protein%2C and plant PHO1%2C that may be involved in phosphate transport
chr2	445806	448427	-	DDB_G0271594	DDB_G0271594_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271596%22%3EDDB_G0271596%3C%2Fa%3E
chr2	448767	451393	-	DDB_G0271596	DDB_G0271596	NA
chr2	451802	454753	-	DDB_G0271598	tgrS1	NA
chr2	455398	458761	-	DDB_G0271506	pitrm1	ortholog of H. sapiens PITRM1 and S. cerevisiae CYM1 involved in protein degradation
chr2	459066	460684	-	DDB_G0271508	DDB_G0271508_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0271602%22%3EDDB_G0271602%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0289795%22%3EDDB_G0289795%3C%2Fa%3E
chr2	461460	463813	-	DDB_G0271602	DDB_G0271602	NA
chr2	464711	467089	-	DDB_G0271510	DDB_G0271510	NA
chr2	468500	469516	+	DDB_G0271512	trmt61	ortholog of the human TRM61 and yeast GCD14%2C which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA as a heterodimer with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281175%22%3E%3Ci%3Etrmt6%3C%2Fi%3E%3C%2Fa%3E
chr2	469596	471672	-	DDB_G0271514	rpc5	component of the RNA polymerase III complex%3B has similarity to H. sapiens RPC5 and S. cerevisiae RPC37
chr2	472505	473932	-	DDB_G0295819	DDB_G0295819	contains a putative N-terminal signal sequence and C-terminal transmembrane domain
chr2	474534	478172	-	DDB_G0271606	DDB_G0271606	NA
chr2	480277	488472	+	DDB_G0271608	rev3	ortholog of DNA polymerase zeta catalytic subunit%2C involed in DNA repair
chr2	488534	493615	-	DDB_G0271610	DDB_G0271610	NA
chr2	494360	495460	-	DDB_G0271516	DDB_G0271516	NA
chr2	497016	498213	-	DDB_G0271518	aslJ_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0273305%22%3EaslJ-1%3C%2Fa%3E 
chr2	499181	506804	+	DDB_G0271520	pks5	putative type I iterative polyketide synthase
chr2	507457	516313	+	DDB_G0271524	pks6	putative type I iterative polyketide synthase
chr2	517604	518599	-	DDB_G0271526	DDB_G0271526	NA
chr2	519478	527091	+	DDB_G0271614	pks7	putative type I iterative polyketide synthase
chr2	527305	528270	+	DDB_G0271528	DDB_G0271528	NA
chr2	529289	530585	-	DDB_G0271568	DDB_G0271568_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	530981	538599	+	DDB_G0271618	pks8	putative type I iterative polyketide synthase
chr2	539055	540421	+	DDB_G0271622	DDB_G0271622_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr2	541447	550308	+	DDB_G0271530	pks9	putative type I iterative polyketide synthase%3B expressed in upper and lower cups during culmination
chr2	550427	552387	-	DDB_G0271532	DDB_G0271532	there is an identical copy of this gene on chromosome 5%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0295661%22%3EDDB_G0295661%3C%2Fa%3E
chr2	553300	553863	+	DDB_G0271534	DDB_G0271534	NA
chr2	555496	556890	+	DDB_G0271536	rcnA	NA
chr2	557800	562277	-	DDB_G0271624	DDB_G0271624	NA
chr2	563064	568601	+	DDB_G0271626	dotA	H3K79 methyltransferase in %3Ci%3EDictyostelium%3C%2Fi%3E%2C involved in development   and DNA repair%3B similar to %3Ci%3ES. cerevisiae%3C%2Fi%3E DOT1%2C which functions in gene silencing at telomeres and DNA repair%2C and is cell cycle regulated%3B %3Ci%3EDictyostelium%3C%2Fi%3E Dot1 however%2C is not cell cycle dependent
chr2	568653	570406	-	DDB_G0271538	DDB_G0271538	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family%3B expressed in pstO cells
chr2	572266	575098	+	DDB_G0271628	dlpC	NA
chr2	575486	577231	+	DDB_G0271630	sac1	conserved protein from yeast to human%3B in yeast involved in protein trafficking and secretion
chr2	577332	578468	-	DDB_G0271570	DDB_G0271570	NA
chr2	580601	582875	+	DDB_G0271632	pus7	ortholog of S. cerevisiae PUS7%2C which catalyzes pseudouridylation at position 35 in U2 snRNA%2C position 50 in 5S rRNA%2C position 13 in cytoplasmic tRNAs%2C and position 35 in pre-tRNA(Tyr)%3B conserved in archaea%2C vertebrates%2C and some bacteria
chr2	583523	586607	+	DDB_G0271634	DDB_G0271634	NA
chr2	587121	590511	+	DDB_G0271636	DDB_G0271636	NA
chr2	590623	593082	-	DDB_G0271542	DDB_G0271542_ps	putative pseudogene%3B similar to family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271462%22%3EDDB_G0271462%3C%2Fa%3E
chr2	593663	597179	+	DDB_G0271638	DDB_G0271638	NA
chr2	597228	599171	-	DDB_G0271640	DDB_G0271640	NA
chr2	601251	605014	-	DDB_G0271572	exosc10	ortholog of mammalian EXOSC10 and yeast RRP6%2C exonuclease component of the nuclear exosome%3B in human%2C part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance
chr2	605879	607395	-	DDB_G0271544	acat	 acetyl-CoA C-acetyltransferase%2C catalyzes the reaction 2 acetyl-CoA %3C%3D%3E CoA %2B acetoacetyl-CoA
chr2	608312	611935	-	DDB_G0271500	keaA	keaA plays a role in the regulation of growth%2C development%2C and stress survival
chr2	614231	614775	+	DDB_G0271642	cks1	ortholog of the conserved CKS1 protein%2C which binds to the catalytic subunit of cyclin dependent kinases and is essential for their biological function
chr2	615393	616101	+	DDB_G0295477	nip7	ortholog of the conserved NIP7 nucleolar protein that is required for 60S ribosome subunit biogenesis%3B contains a PUA domain
chr2	616734	617613	-	DDB_G0271574	DDB_G0271574	NA
chr2	618122	619780	+	DDB_G0271576	DDB_G0271576_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	618267	618339	+	DDB_G0294829	tRNA-Arg-UCU-2	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	620269	621713	-	DDB_G0271546	DDB_G0271546	NA
chr2	622207	631494	-	DDB_G0271502	lvsD	cytosolic protein that regulates contractile vacuole organization
chr2	632125	633298	+	DDB_G0271548	DDB_G0271548	NA
chr2	634463	636022	+	DDB_G0271550	DDB_G0271550	protein serine%2Fthreonine kinase%2C CAMK group%2C CAMK1 family%3B similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases
chr2	637163	639576	+	DDB_G0271552	DDB_G0271552	contains one SAM (sterile alpha motif) domain and PH (pleckstrin homology) domain
chr2	639768	640024	-	DDB_G0271554	DDB_G0271554	NA
chr2	640693	640960	-	DDB_G0271578	DDB_G0271578	NA
chr2	642805	643631	+	DDB_G0271582	mdn1_ps3	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0295765%22%3E%3Ci%3Emdn1%3C%2Fi%3E%3C%2Fa%3E
chr2	644311	647239	-	DDB_G0271556	tgrJ1	conserved hypothetical protein%3B contains an IPT%2FTIG domain found in cell surface receptors
chr2	647755	650574	+	DDB_G0271586	tgrK1	NA
chr2	651346	653954	+	DDB_G0271646	tgrK2	NA
chr2	654222	654583	-	DDB_G0271648	mdn1_ps2	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0295765%22%3E%3Ci%3Emdn1%3C%2Fi%3E%3C%2Fa%3E
chr2	654748	657148	+	DDB_G0271558	DDB_G0271558	NA
chr2	657094	659446	-	DDB_G0271650	tgrJ_ps1	putative pseudogene%3B immunoglobulin E-set family gene
chr2	659629	661323	+	DDB_G0271652	tgrJ_ps2	putative pseudogene%3B immunoglobulin E-set family gene
chr2	661610	662555	+	DDB_G0271654	tgrK3	NA
chr2	665072	665359	-	DDB_G0271656	DDB_G0271656	highly similar to %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0272316%22%3E%3Ci%3EDDB_G0272316%3C%2Fi%3E%3C%2Fa%3E
chr2	665896	666158	-	DDB_G0271560	DDB_G0271560	NA
chr2	666617	666877	-	DDB_G0271588	DDB_G0271588	NA
chr2	667530	667827	-	DDB_G0271658	DDB_G0271658	NA
chr2	668886	681361	+	DDB_G0271504	lvsB	similar to human LYST and mouse Beige proteins
chr2	681736	683293	+	DDB_G0271562	orcD	DNA replication initiation is driven by a conserved six protein complex%2C the origin recognition complex (ORC)%3B has a role in both chromosomal replication and mating type transcriptional silencing
chr2	683417	684658	-	DDB_G0271564	pdhX	putative ortholog of the pyruvate dehydrogenase complex component X (PDHX) that functions to link E2 (%3Ca href%3D%22 %2Fgene%2FDDB_G0277847%22%3EphdC%3C%2Fa%3E%3B dihydrolipoamide acetyltransferase) to E3 (%3Ca href%3D%22 %2Fgene%2FDDB_G0291648%22%3Elpd%3C%2Fa%3E%3B dihydrolipoamide dehydrogenase)%3B in addition%2C the complex contains the E1 components (%3Ca href%3D%22 %2Fgene%2FDDB_G0292994%22%3EphdA%3C%2Fa%3E%2C %3Ca href%3D%22 %2Fgene%2FDDB_G0276417%22%3EphdB%3C%2Fa%3E)
chr2	685414	686952	-	DDB_G0271660	fmoB	belongs to the fmo family%3B similar to flavin-containing monooxygenases from a variety of eukaryotes%3B involved in the metabolism of xenobiotic compounds
chr2	687700	695254	-	DDB_G0271662	pks10	putative type I iterative polyketide synthase
chr2	696177	697095	+	DDB_G0271590	omt1	NA
chr2	697134	699280	-	DDB_G0271592	DDB_G0271592	NA
chr2	706981	708744	+	DDB_G0271784	DDB_G0271784	NA
chr2	711253	712249	+	DDB_G0271748	DDB_G0271748_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0292574%22%3EDDB_G0292574%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0295807%22%3EDDB_G0295807%3C%2Fa%3E
chr2	712435	716021	-	DDB_G0271786	DDB_G0271786	NA
chr2	716526	717712	+	DDB_G0271788	wdr57	ortholog of human WDR57%2C which binds PRP8%3B contains 7 WD40 repeats
chr2	718547	719569	+	DDB_G0271736	rabC	NA
chr2	720888	724093	+	DDB_G0271750	nfaA	putative ortholog of human NF1%2C a GAP which regulates p21-ras signaling%3B regulates chemotaxis%2C probably  though the control of RasG activity
chr2	724441	725418	-	DDB_G0271704	DDB_G0271704	NA
chr2	725506	726207	-	DDB_G0271702	DDB_G0271702	NA
chr2	727031	728611	+	DDB_G0271738	tubC	NA
chr2	728723	729221	-	DDB_G0271790	tmem14B	one of two Dictyostelium proteins in the eukaryotic transmembrane protein 14 (TMEM14) family%3B contains four putative transmembrane domains
chr2	729816	730550	+	DDB_G0271792	arrC	NA
chr2	730777	731676	-	DDB_G0271700	DDB_G0271700	contains a thioredoxin domain%2C which functions as a general disulfide isomerase%3B enriched in gametes
chr2	733224	733804	-	DDB_G0271668	rpl36	protein component of the large (60S) ribosomal subunit
chr2	734961	736353	+	DDB_G0271752	DDB_G0271752	NA
chr2	736637	737773	+	DDB_G0271698	DDB_G0271698	NA
chr2	738043	739981	-	DDB_G0271666	prtB	cAMP-responsive gene
chr2	741000	742942	-	DDB_G0271696	prtA	cAMP-responsive gene
chr2	743389	746843	-	DDB_G0271754	DDB_G0271754	contains one PHD-type zinc finger domain%3B contains one SPRY domain%3B weak similarity to human ASH2L (Set1%2FAsh2 histone methyltransferase complex subunit ASH2)
chr2	747447	748888	+	DDB_G0271794	captA	catalyzes the reaction CDP-choline %2B 1%2C2-diacylglycerol %3D CMP %2B a phosphatidylcholine%3B putative ortholog of human CEPT1
chr2	749196	749509	-	DDB_G0271756	DDB_G0271756	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon  
chr2	750344	752594	-	DDB_G0271694	DDB_G0271694	NA
chr2	753355	754395	+	DDB_G0271796	DDB_G0271796	putative ortholog of human RUSD1
chr2	755175	758249	+	DDB_G0271798	DDB_G0271798	highly similar to H. sapiens USP22 and USP51
chr2	758362	762958	-	DDB_G0271692	comC	similar to Mus musculus MEGF11 PROTEIN (KIAA1781)%3B contains 14 EGF domains
chr2	763571	766181	+	DDB_G0271690	DDB_G0271690	contains one NIF domain and one BRCT domain
chr2	766288	768273	-	DDB_G0271758	rccA	NA
chr2	770369	770655	+	DDB_G0271800	DDB_G0271800	NA
chr2	771015	772141	-	DDB_G0271760	ipkA1	NA
chr2	773062	775760	-	DDB_G0271688	grlO	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr2	776318	778661	-	DDB_G0271686	grlB	major GABA receptor during early development
chr2	779738	782211	-	DDB_G0271684	grlA	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature%3B plays a role in sporulation
chr2	783832	784785	+	DDB_G0271802	DDB_G0271802	NA
chr2	785458	785736	+	DDB_G0271804	DDB_G0271804	NA
chr2	787444	791676	+	DDB_G0271806	rapgap3	weakly similar to H. sapiens signal-induced proliferation-associated 1-like protein 1 (Spa-1)
chr2	792553	796032	+	DDB_G0271682	DDB_G0271682	member of the TKL (tyrosine kinase-like) group%3B belongs to the ARK (ankyrin repeat-containing kinase) family%2C although it does not contain ankyrin repeats%3B contains two kinase domains%2C one of which is predicted to be inactive
chr2	796698	797982	+	DDB_G0271680	DDB_G0271680	NA
chr2	798398	802915	+	DDB_G0271808	DDB_G0271808	NA
chr2	803219	803502	-	DDB_G0271810	DDB_G0271810	NA
chr2	805322	807046	-	DDB_G0271812	DDB_G0271812	similar to H. sapiens formin-binding protein 1 (FNBP1) involved in regulation of the actin cytoskeleton during endocytosis%3B chromosomal aberrations involving FNBP1 are also found in acute leukemias
chr2	809928	811771	+	DDB_G0271678	pckA	expressed in pstO cells and upper cup during culmination
chr2	812738	814339	+	DDB_G0271676	nlp	NA
chr2	814850	815433	+	DDB_G0271674	DDB_G0271674_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0267754%22%3EDDB_G0267754%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290971%22%3EDDB_G0290971%3C%2Fa%3E 
chr2	815855	817023	-	DDB_G0271814	DDB_G0271814	NA
chr2	818432	819693	+	DDB_G0271672	DDB_G0271672	member of the ZIP (Zrt- and Irt-like Protein) family capable of transporting zinc and other metal ions%3B contains 6 transmembrane domains
chr2	820254	821485	-	DDB_G0271670	lsr1	NA
chr2	825354	829079	+	DDB_G0271816	DDB_G0271816	NA
chr2	829537	830065	-	DDB_G0271706	tbcA	NA
chr2	830367	833093	+	DDB_G0271708	ddx31	ortholog of H. sapiens DDX31 and S. cerevisiae DBP7 (Dead Box Protein 7)
chr2	833213	833567	-	DDB_G0295685	sigN10	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B antibodies against this protein inhibits aggregation
chr2	834356	834685	-	DDB_G0271710	DDB_G0271710_ps	NA
chr2	835390	835739	+	DDB_G0271712	sigN6	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B antibodies against this protein inhibits aggregation
chr2	836349	836688	-	DDB_G0271714	sigN12	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B developmental expression pattern altered in GBF null cells
chr2	837375	837721	+	DDB_G0271818	sigN7	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B antibodies against this protein inhibits aggregation
chr2	837872	839063	-	DDB_G0271820	DDB_G0271820	almost identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0271720%22%3E%3Ci%3EDDB_G0271720%3C%2Fi%3E%3C%2Fa%3E (92%25 identity%2C 95%25 similarity)
chr2	839761	840107	-	DDB_G0271822	sigN11	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B antibodies against this protein inhibits aggregation
chr2	840762	841112	+	DDB_G0271824	sigN8	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B antibodies against this protein inhibits aggregation
chr2	841529	841870	-	DDB_G0271716	sigN14	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B antibodies against this protein inhibits aggregation
chr2	842563	842912	+	DDB_G0271718	sigN9	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B antibodies against this protein inhibits aggregation
chr2	843067	844242	-	DDB_G0271720	DDB_G0271720	almost identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0271820%22%3E%3Ci%3EDDB_G0271820%3C%2Fi%3E%3C%2Fa%3E (92%25 identity%2C 95%25 similarity)
chr2	844656	845699	+	DDB_G0271722	DDB_G0271722	similar to extracellular matrix protein%3B contains a putative signal peptide
chr2	845885	849443	+	DDB_G0271826	DDB_G0271826_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0287123%22%3EDDB_G0287123%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0286981%22%3EDDB_G0286981%3C%2Fa%3E
chr2	849998	850921	+	DDB_G0271762	DDB_G0271762_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271764%22%3EDDB_G0271764%3C%2Fa%3E 
chr2	851193	852713	+	DDB_G0271764	DDB_G0271764	NA
chr2	853054	855615	-	DDB_G0271828	DDB_G0271828	contains 5 coiled-coil domains
chr2	857132	858107	+	DDB_G0271724	DDB_G0271724	NA
chr2	858649	859548	+	DDB_G0271726	DDB_G0271726	NA
chr2	860066	865156	-	DDB_G0271766	pARTg	NA
chr2	865698	866057	-	DDB_G0271768	pARTg_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271766%22%3E%3Ci%3EpARTg%3C%2Fi%3E%3C%2Fa%3E 
chr2	866554	867057	-	DDB_G0271728	DDB_G0271728	NA
chr2	868232	872209	+	DDB_G0271730	DDB_G0271730	NA
chr2	872358	875432	-	DDB_G0271732	DDB_G0271732	highly similar to mammalian DNA-binding protein SMUBP-2 (IGHMBP2)%2C involved in muscular atrophy and other diseases%3B putative ortholog of %3Ci%3ES. cerevisiae HCS1%3C%2Fi%3E%2C a DNA helicase associated with alpha DNA polymerase
chr2	876349	877583	+	DDB_G0271830	DDB_G0271830	NA
chr2	877919	878191	-	DDB_G0271770	DDB_G0271770	this gene is very similar to four almost identical genes on C4 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284931%22%3E%3Ci%3EDDB_G0284931%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284927%22%3E%3Ci%3EDDB_G0284927%3C%2Fi%3E%3C%2Fa%3E)
chr2	882440	885695	+	DDB_G0271734	rapgap1	stimulates the RapA (Rap1) GTPase activity during chemotaxis%2C which results in the downregulation of actin polymerization at the leading edge
chr2	887242	889759	-	DDB_G0271832	DDB_G0271832	NA
chr2	890518	891898	+	DDB_G0271774	uqcrh	similar to the hinge protein of the ubiquinol-cytochrome C reductase complex%2C involved in respiration
chr2	895254	896937	+	DDB_G0271778	cyp516B1	NA
chr2	897538	898749	+	DDB_G0271740	DDB_G0271740	NA
chr2	899784	901031	+	DDB_G0271780	DDB_G0271780	NA
chr2	901139	903697	-	DDB_G0271834	DDB_G0271834	NA
chr2	904078	904692	-	DDB_G0271836	DDB_G0271836	NA
chr2	905039	909261	-	DDB_G0271838	DDB_G0271838	similar to D. purpureum protein
chr2	909593	910039	-	DDB_G0271840	DDB_G0271840	NA
chr2	910931	911581	-	DDB_G0271742	DDB_G0271742	NA
chr2	912630	914082	+	DDB_G0271842	scsC	catalyzes the reaction ATP %2B succinate %2B CoA %3D ADP %2B phosphate %2B succinyl-CoA
chr2	914753	919787	-	DDB_G0271844	DDB_G0271844	NA
chr2	920601	924281	+	DDB_G0294587	DDB_G0294587	NA
chr2	925396	925833	-	DDB_G0271878	DDB_G0271878	NA
chr2	926405	926842	-	DDB_G0271872	DDB_G0271872	NA
chr2	930648	932648	+	DDB_G0271880	DDB_G0271880	similar to the uncharacterized %3Ci%3EH. sapiens %3C%2Fi%3E C16orf70 
chr2	932853	934261	-	DDB_G0271858	gmppA	catalyzes the reaction GTP %2B alpha-D-mannose 1-phosphate %3C%3D%3E diphosphate %2B GDP-mannose
chr2	939689	941371	+	DDB_G0271860	DDB_G0271860	dual specificity phosphatases remove phosphate groups from tyrosine and serine%2Fthreonine residues 
chr2	942083	942818	-	DDB_G0271882	vatF	ortholog of the F subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the F subunit is part of the V1 subunit
chr2	944209	945663	+	DDB_G0271862	eif2s1	EIF2S1 ortholog%2C the eukaryotic initiation factor 2 alpha subunit%3B in human%2C binds to the 40S ribosome and to the mRNA for form a preinitiation complex%3B contains an S1 RNA-binding domain characteristic of eIF2alpha
chr2	946406	947600	+	DDB_G0271848	porA	porin of the outer mitochondrial membrane%2C a wide voltage-gated channel for a variety of ions
chr2	957017	959218	+	DDB_G0271850	DDB_G0271850	NA
chr2	960951	964640	+	DDB_G0271868	gefS	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr2	965144	966313	-	DDB_G0271852	rtaA	the rtaA expression pattern in a subset of anterior-like cells has led to the identification of a prestalk cell type: the pstU cells%2C which preferentially populate the upper cup region at culmination%3B contains 7 predicted transmembrane domains
chr2	967334	968952	-	DDB_G0271876	DDB_G0271876	NA
chr2	969621	970469	+	DDB_G0271854	DDB_G0271854	NA
chr2	970613	973266	-	DDB_G0271856	vps52C	similar to S. cerevisiae VPS52%2C component of the GARP (Golgi-associated retrograde protein) complex
chr2	973836	974831	-	DDB_G0271884	DDB_G0271884	conserved putative quinone oxidoreductase%2C belongs to the broader superfamily of zinc-dependent alcohol dehydrogenases
chr2	975850	979616	+	DDB_G0271870	agnC	NA
chr2	980070	980546	+	DDB_G0271864	mocs2l	NA
chr2	980879	981778	+	DDB_G0271866	DDB_G0271866	belongs to the crotonase superfamily%3B similar to fungal and bacterial proteins of the enoyl-CoA hydratase%2Fisomerase family%3B predicted to be mitochondrial
chr2	981925	985047	-	DDB_G0271886	DDB_G0271886	NA
chr2	985804	986106	-	DDB_G0295809	DDB_G0295809	similar to conserved bacterial proteins
chr2	986307	987317	-	DDB_G0295807	DDB_G0295807	NA
chr2	994788	995996	-	DDB_G0271954	DDB_G0271954_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	996180	996250	-	DDB_G0295005	tRNA-Gly-GCC-3	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr2	996675	998009	+	DDB_G0271952	DDB_G0271952_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	1000440	1001189	-	DDB_G0271914	DDB_G0271914	contains a signal peptide
chr2	1002205	1003631	-	DDB_G0271950	DDB_G0271950	NA
chr2	1004091	1005698	+	DDB_G0271912	DDB_G0271912	NA
chr2	1006829	1009301	+	DDB_G0271948	DDB_G0271948	NA
chr2	1009716	1013813	+	DDB_G0271946	DDB_G0271946	NA
chr2	1014827	1015930	+	DDB_G0271916	rtoA	contains several repeats of a serine-rich motif%2C which catalyzes the fusion of phospholipid vesicles
chr2	1016342	1017971	-	DDB_G0271944	DDB_G0271944	NA
chr2	1018193	1019142	+	DDB_G0271910	DDB_G0271910	ortholog of human MCTS1 which is an anti-oncogene that may play a role in cell cycle regulation%3B contains a PUA domain which is predicted to bind RNA 
chr2	1019381	1020471	-	DDB_G0271942	arl5	NA
chr2	1020910	1023896	-	DDB_G0271956	DDB_G0271956	member of the TRIAD family%2C which contain an IBR Zn finger (C6HC domain) flanked by two RING fingers
chr2	1024732	1025457	-	DDB_G0271908	mrrA	transcriptional target of MybE%3B expressed in upper and lower cup cells%3B  contains a predicted signal peptide and a C-terminal transmembrane domain
chr2	1025973	1027199	-	DDB_G0271938	DDB_G0271938	putative pseudogene%3B similar to a large gene family encoding FNIP repeat-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290067%22%3E%3Ci%3EcigB%3C%2Fi%3E%3C%2Fa%3E 
chr2	1027709	1028016	-	DDB_G0271930	DDB_G0271930	NA
chr2	1028566	1028884	+	DDB_G0271918	DDB_G0271918	NA
chr2	1028961	1029266	-	DDB_G0271920	DDB_G0271920	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon
chr2	1030563	1031954	+	DDB_G0271936	DDB_G0271936	NA
chr2	1032903	1033206	+	DDB_G0271888	DDB_G0271888	NA
chr2	1033465	1034601	-	DDB_G0271890	DDB_G0271890	NA
chr2	1035063	1035919	-	DDB_G0271892	DDB_G0271892	similar to bacterial glutathione S-transferase%3B catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione
chr2	1037222	1039393	+	DDB_G0271894	DDB_G0271894	NA
chr2	1039722	1040055	-	DDB_G0271934	DDB_G0271934	weakly similar to hssA%2F2C%2F7E family protein%3B N terminal exon is 10 nt rather than 13 as the other genes of that family 
chr2	1041429	1041803	-	DDB_G0271896	DDB_G0271896	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon
chr2	1042985	1043533	-	DDB_G0271898	DDB_G0271898	NA
chr2	1044061	1047414	-	DDB_G0271900	DDB_G0271900	NA
chr2	1048524	1049907	+	DDB_G0271924	aspA	catalyzes the reaction L-asparagine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E L-aspartate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr2	1050008	1051024	-	DDB_G0271922	mcfI	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3B regulated by the MADS-box transcription factor SrfA during development %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr2	1052190	1056618	+	DDB_G0271928	DDB_G0271928	NA
chr2	1056759	1058327	-	DDB_G0271902	pscA	ortholog of prokaryotic penicillin-binding protein 4 (PBP4)%3B inhibited by penicillin G
chr2	1058890	1061065	-	DDB_G0271904	DDB_G0271904	catalyzes the reaction GTP %2B oxaloacetate %3D GDP %2B phosphoenolpyruvate %2B CO%3Csub%3E2%3C%2Fsub%3E in gluconeogenesis and the TCA cycle
chr2	1062208	1063962	-	DDB_G0271906	mgluS	catalyzes the reaction ATP %2B L-glutamate %2B tRNAGlu %3D AMP %2B diphosphate %2B L-glutamyl-tRNAGlu
chr2	1066723	1070060	+	DDB_G0271926	DDB_G0271926	NA
chr2	1070817	1073403	+	DDB_G0272052	DDB_G0272052	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D
chr2	1074422	1075280	-	DDB_G0271958	DDB_G0271958	catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione
chr2	1075826	1077842	-	DDB_G0272034	DDB_G0272034	NA
chr2	1078393	1080159	-	DDB_G0271960	mccB	catalyzes the reaction ATP %2B 3-methylcrotonoyl-CoA %2B HCO%3Csub%3E3%3C%2Fsub%3E%3Csup%3E-%3C%2Fsup%3E %3C%3D%3E ADP %2B phosphate %2B 3-methylglutaconyl-CoA
chr2	1080455	1081855	-	DDB_G0271962	DDB_G0271962	NA
chr2	1084003	1084462	+	DDB_G0271964	DDB_G0271964_ps	putative pseudogene%3B poly(ADP-ribose) polymerase family protein
chr2	1085006	1085428	+	DDB_G0271966	DDB_G0271966	NA
chr2	1086145	1087954	+	DDB_G0271968	DDB_G0271968	similar to human LMAN1 (lectin mannose-binding protein 1)%3B belongs to the legume-like lectin family%3B contains 1 predicted transmembrane domain%3B similar to D. purpureum protein
chr2	1088983	1090689	+	DDB_G0271970	DDB_G0271970	NA
chr2	1092100	1092318	+	DDB_G0271972	DDB_G0271972	NA
chr2	1094076	1094714	+	DDB_G0272036	rpb10	subunit common to RNA polymerases I%2C II and III%3B ortholog of S. cerevisiae RPB10
chr2	1095789	1096190	+	DDB_G0271976	rpl32	protein component of the large (60S) ribosomal subunit
chr2	1096689	1096850	-	DDB_G0271978	epnA_ps1	putative pseudogene%3B small fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291512%22%3E%3Ci%3EepnA%3C%2Fi%3E%3C%2Fa%3E 
chr2	1097988	1098911	-	DDB_G0271980	rabR	NA
chr2	1099522	1100310	-	DDB_G0294569	DDB_G0294569	NA
chr2	1100914	1102879	-	DDB_G0272054	DDB_G0272054	NA
chr2	1103704	1105953	-	DDB_G0271982	DDB_G0271982	NA
chr2	1107152	1111913	+	DDB_G0272032	gefG	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form
chr2	1113320	1114208	+	DDB_G0271984	rab5A	similar to H. sapiens rab5
chr2	1115108	1118319	+	DDB_G0272056	DDB_G0272056	putative ortholog of H. sapiens CNOT3 and S. cerevisiae  NOT3%3B component of the CCR4-NOT transcription complex
chr2	1118852	1119382	+	DDB_G0271986	DDB_G0271986	NA
chr2	1119945	1122212	+	DDB_G0272038	rgfA	contains one vacuolar sorting protein 9 (Vps9) domain
chr2	1122814	1123518	+	DDB_G0294583	DDB_G0294583	NA
chr2	1123795	1124312	-	DDB_G0272040	DDB_G0272040	NA
chr2	1124620	1127271	-	DDB_G0272058	DDB_G0272058	similar to other Dictyostelium genes%2C although shorter at the carboxyl terminus
chr2	1127658	1127801	-	DDB_G0272010	rrpB_ps	putative pseudogene%3B small fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291249%22%3E%3Ci%3ErrpB%3C%2Fi%3E%3C%2Fa%3E 
chr2	1129144	1130760	-	DDB_G0271994	DDB_G0271994	%3Cb%3ECommunity annotation: %3C%2Fb%3EThis protein may be a highly diverged monomeric %3Ca target %3D%22new%22 href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0282499%22%3EE2F%3C%2Fa%3E. %3Ci%3EHarry MacWilliams%2C February 2011%3C%2Fi%3E 
chr2	1132270	1135083	-	DDB_G0271996	DDB_G0271996	contains four FNIP repeats%3B similar to cmbB%2C cigB%2C and other conserved hypothetical Dictyostelium proteins
chr2	1135748	1137670	-	DDB_G0271998	fsjB	RrmJ%2FFtsJ ribosomal RNA methyltransferase family member%3B well conserved heat shock proteins present in prokaryotes%2C archaea%2C and eukaryotes%3B similar to S. cerevisiae MRM2 required for methylation of U(2791) in 21S rRNA
chr2	1137998	1141185	-	DDB_G0272000	DDB_G0272000	NA
chr2	1142461	1142977	+	DDB_G0271992	DDB_G0271992	NA
chr2	1143353	1144285	+	DDB_G0271990	DDB_G0271990	NA
chr2	1144876	1146424	+	DDB_G0271988	DDB_G0271988	contains 7 putative transmembrane domains%3B similar to D. purpureum protein
chr2	1146550	1148085	-	DDB_G0272060	DDB_G0272060	NA
chr2	1148337	1148777	-	DDB_G0272062	DDB_G0272062	NA
chr2	1150556	1158821	+	DDB_G0272064	DDB_G0272064	NA
chr2	1159049	1160899	-	DDB_G0272066	DDB_G0272066	NA
chr2	1162280	1163790	-	DDB_G0272042	DDB_G0272042	NA
chr2	1164190	1165207	-	DDB_G0272002	egeA	NA
chr2	1165671	1167128	-	DDB_G0272004	p2xA	membrane ion channel activated by ATP%3B may be involved in intracellular calcium signaling
chr2	1167768	1169576	-	DDB_G0272006	DDB_G0272006	similar to H. sapiens Down syndrome critical region protein 5%3B the Dictyostelium protein is much longer (602 amino acids compared to 134 amino acids for the human gene)%3B has two predicted transmembrane domains
chr2	1170947	1172056	+	DDB_G0272012	DDB_G0272012	members of this family are membrane proteins involved in long chain fatty acid elongation systems that produce 26-carbon precursors for ceramide and sphingolipid synthesis%3B contains 7 putative transmembrane domains
chr2	1172213	1173929	-	DDB_G0272014	DDB_G0272014	belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B similar to human AADAT (kynurenine%2Falpha-aminoadipate aminotransferase) and S. cerevisiae ARO8 (aromatic amino acid aminotransferase)
chr2	1175168	1176445	+	DDB_G0272016	DDB_G0272016	the DCUN1 domain is found in the eukaryotic %27defective in cullin neddylation%27 (DCN) protein family
chr2	1176734	1178544	-	DDB_G0272018	mvk	conserved eukaryotic kinase (human MVK%2C yeast ERG12) that plays a role in the synthesis of isopentanyl pyrophosphate%2C a common intermediate in pathways including cholesterol biosynthesis
chr2	1179282	1181834	+	DDB_G0272020	DDB_G0272020	contains an N-terminal F-box domain%2C a central SH2 domain%2C and C-terminal ankyrin repeats
chr2	1182004	1183004	-	DDB_G0272022	rpc34	component of the RNA polymerase III complex%3B has similarity to H. sapiens RPC6%2FRPC39 and S. cerevisiae RPC34
chr2	1183612	1185141	-	DDB_G0272024	DDB_G0272024	NA
chr2	1185450	1185539	-	DDB_G0348861	DDB_G0348861	NA
chr2	1185842	1186168	-	DDB_G0272026	DDB_G0272026	NA
chr2	1186737	1189078	-	DDB_G0272028	DDB_G0272028	NA
chr2	1189650	1190482	-	DDB_G0272030	DDB_G0272030	NA
chr2	1193466	1194641	-	DDB_G0272048	DDB_G0272048	NA
chr2	1194853	1195221	-	DDB_G0272050	DDB_G0272050_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0270330%22%3EDDB_G0270330%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270366%22%3EDDB_G0270366%3C%2Fa%3E
chr2	1196033	1196610	+	DDB_G0272086	DDB_G0272086_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0270368%22%3EDDB_G0270368%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0270328%22%3EDDB_G0270328%3C%2Fa%3E
chr2	1197926	1198808	-	DDB_G0272094	DDB_G0272094	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein similar to bacterial proteins%3B contains a predicted signal peptide
chr2	1199474	1199641	-	DDB_G0272068	DDB_G0272068_ps	putative pseudogene%3B fragment of D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0270330%22%3EDDB_G0270330%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270366%22%3EDDB_G0270366%3C%2Fa%3E
chr2	1200085	1200719	+	DDB_G0272088	DDB_G0272088_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0270778%22%3EDDB_G0270778%3C%2Fa%3E
chr2	1201188	1203332	-	DDB_G0272070	DDB_G0272070	NA
chr2	1203890	1208907	+	DDB_G0272096	DDB_G0272096	NA
chr2	1209397	1212729	-	DDB_G0272098	DDB_G0272098	NA
chr2	1214216	1215418	-	DDB_G0272072	DDB_G0272072	NA
chr2	1216065	1216640	+	DDB_G0272074	DDB_G0272074	NA
chr2	1216702	1219488	-	DDB_G0272090	DDB_G0272090	contains 5 putative transmembrane domains%3B similar to D. purpureum protein
chr2	1220684	1222754	-	DDB_G0272076	eif3L	EIF3L ortholog%2C has been shown in human to bind EIF3E
chr2	1223494	1226750	+	DDB_G0272078	eif3A	EIF3A ortholog%2C the eukaryotic initiation factor theta subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr2	1227402	1233247	+	DDB_G0272100	DDB_G0272100	NA
chr2	1233762	1238792	+	DDB_G0272102	DDB_G0272102	NA
chr2	1238870	1243718	-	DDB_G0272080	gacHH	NA
chr2	1245702	1251311	+	DDB_G0272082	DDB_G0272082	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr2	1251605	1255395	-	DDB_G0272092	DDB_G0272092	member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family%3B contains a C2 domain (Ca2%2B-dependent membrane-targeting module)%2C an ankyrin repeat region%2C and a SAM (Sterile alpha motif) domain
chr2	1258878	1259135	+	DDB_G0272308	rps29	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S29 homolog
chr2	1259741	1264081	-	DDB_G0272310	DDB_G0272310_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0272314%22%3EDDB_G0272314%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0272096%22%3EDDB_G0272096%3C%2Fa%3E
chr2	1264510	1269657	-	DDB_G0272314	DDB_G0272314	NA
chr2	1270771	1271085	+	DDB_G0272316	DDB_G0272316	highly similar to %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0271656%22%3E%3Ci%3EDDB_G0271656%3C%2Fi%3E%3C%2Fa%3E
chr2	1271354	1276784	-	DDB_G0272354	spt6	ortholog of the human SUPT6H and similar to S. cerevisiae SPT6 (suppressor of Ty 6)
chr2	1278811	1280712	+	DDB_G0272318	DDB_G0272318	functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC)%3B contains a N-terminal importin beta binding domain (IBB domain)
chr2	1281320	1283399	-	DDB_G0272108	DDB_G0272108	shares a short region of similarity with the splicing regulator TIA-1%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0272108%22%3Ecommunity annotation%3C%2Fa%3E
chr2	1283864	1284823	-	DDB_G0272320	snrpb	similar to human SNRPB and SNRPN
chr2	1285359	1286321	-	DDB_G0272322	DDB_G0272322	NA
chr2	1287157	1288101	+	DDB_G0272324	sbds	orthlog of the human SBDS protein%2C which is mutated in a majority of patients with Shwachman-Bodian-Diamond syndrome%3B localizes to the pseudopodia in cAMP gradient
chr2	1288191	1289623	-	DDB_G0272326	nudE	nuclear distribution gene E-like protein
chr2	1290469	1292935	-	DDB_G0272356	DDB_G0272356	NA
chr2	1293361	1294394	+	DDB_G0272358	DDB_G0272358	NA
chr2	1294745	1296604	+	DDB_G0272360	taf9	subunit of TFIID and SAGA complexes%2C involved in RNA polymerase II transcription initiation and in chromatin modification
chr2	1296713	1298183	-	DDB_G0272362	gtf2h2	general transcription factor required for the initiation of transcription by RNA polymerase II
chr2	1298775	1299620	+	DDB_G0272328	DDB_G0272328	NA
chr2	1300433	1304396	+	DDB_G0272330	DDB_G0272330_ps	putative pseudogene%3B similar to EGF repeat-containing proteins such as %3Ca href%3D%22%2Fgene%2FDDB_G0272364%22%3EDDB_G0272364%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272366%22%3EDDB_G0272366%3C%2Fa%3E
chr2	1305873	1309568	+	DDB_G0272334	DDB_G0272334_ps	putative pseudogene%3B similar to EGF repeat-containing proteins such as %3Ca href%3D%22%2Fgene%2FDDB_G0272364%22%3EDDB_G0272364%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272366%22%3EDDB_G0272366%3C%2Fa%3E
chr2	1309841	1310835	-	DDB_G0295845	DDB_G0295845	NA
chr2	1311861	1315601	+	DDB_G0272336	DDB_G0272336_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0272366%22%3EDDB_G0272366%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0272364%22%3EDDB_G0272364%3C%2Fa%3E 
chr2	1317794	1322042	+	DDB_G0272364	DDB_G0272364	contains a predicted signal sequence and a putative C-terminal transmembrane domain%3B contains 2 EGF-like domains
chr2	1322780	1326485	+	DDB_G0272366	DDB_G0272366	contains EGF-like domain and an immunoglobulin E-set domain%3B contains a predicted signal peptide and a putative C-terminal transmembrane domain
chr2	1326566	1331617	-	DDB_G0272338	DDB_G0272338	NA
chr2	1331957	1333399	-	DDB_G0272340	DDB_G0272340	NA
chr2	1334436	1336255	-	DDB_G0272110	gskA	protein serine%2Fthreonine kinase%2C GSK family%3B  member of the CMGC kinase group%3B essential for cell specification%2C chemotaxis and cAMP signaling%3B activated by CAR3 through ZAK1 (prespore-)%2C and inhibited by CAR4 (prestalk-) signalling
chr2	1338747	1340380	+	DDB_G0272342	DDB_G0272342	NA
chr2	1340572	1346005	-	DDB_G0272368	ndm	contains a coiled%2C coil%2C C-terminal BAR-like domain
chr2	1346376	1355925	-	DDB_G0272344	htt	ortholog of Huntington%27s disease protein Huntingtin (HTT%3B not to be confused with the human serotonin transporter%2C now named SLC6A4)%3B in %3Ci%3EDictyostelium%3C%2Fi%3E%2C regulates myosin II phosphorylation through phosphatase PP2A%2C affecting chemotaxis and cytokinesis%3B involved in osmoregulation%2C bivalent cation maintenance with effects on development including prespore%2Fspore differentiation%3B also required for calcium chemotaxis and potassium facilitated chemotaxis
chr2	1356603	1357882	+	DDB_G0272346	mcfQ	ortholog of slc25a17%2C a peroximal membrane protein involved in transport of solutes%3B contains five transmembrane domains %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr2	1358012	1359900	-	DDB_G0272348	DDB_G0272348	NA
chr2	1361017	1364559	+	DDB_G0272370	DDB_G0272370	NA
chr2	1365573	1365643	-	DDB_G0295003	tRNA-Pro-UGG-10	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr2	1366581	1367288	+	DDB_G0272130	DDB_G0272130	NA
chr2	1367731	1371168	-	DDB_G0272372	gxcM	NA
chr2	1373618	1374599	+	DDB_G0272250	rps23	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S23 homolog
chr2	1375029	1375823	+	DDB_G0272128	DDB_G0272128	belongs to the short chain dehydrogenases%2Freductases family%3B ortholog of human HSD17B10%2C which is involved in mitochondrial tRNA maturation%2C and%2C by interacting with intracellular amyloid-beta%2C may contribute to the neuronal dysfunction associated with Alzheimer disease 
chr2	1376138	1376356	+	DDB_G0272126	DDB_G0272126	NA
chr2	1376821	1377729	-	DDB_G0272124	kdelr	endoplasmic reticulum receptor for the KDEL signal sequence of proteins resident in the endoplasmic reticulum%3B believed to cycle between the cis side of the Golgi apparatus and the ER
chr2	1378065	1381252	+	DDB_G0272374	prpf6	component of the U5 sRNP complex%3B may act in the tri-snRNP complex as a bridging factor between U5 and U4%2FU6 snRNPs
chr2	1381315	1387377	-	DDB_G0272122	DDB_G0272122	NA
chr2	1388787	1389458	+	DDB_G0272252	DDB_G0272252	NA
chr2	1389998	1391041	+	DDB_G0272376	DDB_G0272376	NA
chr2	1392021	1394702	+	DDB_G0272378	DDB_G0272378	contains a predicted signal sequence and a putative C-terminal transmembrane domain
chr2	1395088	1395892	+	DDB_G0272380	DDB_G0272380	NA
chr2	1396081	1400076	-	DDB_G0272254	DDB_G0272254	member of the TKL (tyrosine kinase-like) group%3B contains a galactose oxidase central domain and three Kelch motifs
chr2	1401273	1403990	-	DDB_G0272382	DDB_G0272382	NA
chr2	1405577	1408869	+	DDB_G0272384	DDB_G0272384	E.coli ATP-dependent DNA helicase RecQ is involved in genome maintenance%3B similar to Bloom syndrome protein%3B defects in BLM cause genetic instability%2C including a high level of sister chromatid exchanges%2C associated with a greatly increased predisposition to a wide range of cancers
chr2	1409267	1411283	-	DDB_G0272190	fam49	conserved protein
chr2	1412468	1413964	+	DDB_G0272192	DDB_G0272192	NA
chr2	1415836	1417310	+	DDB_G0272386	DDB_G0272386	contains an N-terminal F-box domain and five Kelch repeats
chr2	1417426	1419447	-	DDB_G0272388	DDB_G0272388	NA
chr2	1421226	1422709	+	DDB_G0272260	sppA	similar to mammalian sphingosine-1-phosphate phosphatase
chr2	1423166	1426583	+	DDB_G0295821	DDB_G0295821	contains a putative N-terminal signal sequence and 11 additional putative transmembrane domains
chr2	1426809	1428030	-	DDB_G0272116	ppp4c	protein serine%2Fthreonine phosphatase required for chemotaxis and development%3B  suppresses the %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269876%22%3E%3Ci%3EsamkA%3C%2Fi%3E%3C%2Fa%3E (SMEK)%3B ortholog of mammalian PPP4C
chr2	1429556	1430335	+	DDB_G0272262	DDB_G0272262	NA
chr2	1431432	1432313	+	DDB_G0272194	DDB_G0272194	NA
chr2	1433985	1434091	-	DDB_G0272392	gnt_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0272422%22%3E%3Ci%3Egnt7%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0272170%22%3E%3Ci%3Egnt8%3C%2Fi%3E%3C%2Fa%3E
chr2	1434465	1434818	+	DDB_G0272394	ndufa5	accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)
chr2	1435063	1437153	-	DDB_G0272396	DDB_G0272396	contains a putative signal peptide and two predicted transmembrane domains
chr2	1442939	1445914	+	DDB_G0272264	DDB_G0272264	contains two coiled-coil domains%3B predicted to have structural similarity to the beta-sandwich domain of the Sec23%2F24 superfamily 
chr2	1448193	1448897	+	DDB_G0272398	DDB_G0272398	NA
chr2	1449219	1450573	-	DDB_G0272266	ndufa9	accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)
chr2	1452059	1459004	+	DDB_G0272112	myoJ	conditional processive motor protein that can move over long distances along F-actin without disassociating%3B processiveness depends on high physiological Mg%3Csup%3E2%2B%3C%2Fsup%3E concentrations
chr2	1460129	1460770	-	DDB_G0272268	DDB_G0272268_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	1461355	1461630	-	DDB_G0272270	DDB_G0272270_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	1461647	1466514	-	DDB_G0272400	DDB_G0272400_RTE	partial and rearranged ORF1and ORF2  of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	1465351	1465424	-	DDB_G0295001	tRNA-Phe-GAA-9	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	1467056	1468117	-	DDB_G0272196	DDB_G0272196	contains one VWFA domain and one copine domain%3B copines are phospholipid-binding proteins
chr2	1469033	1470032	+	DDB_G0272402	DDB_G0272402	NA
chr2	1470684	1471898	+	DDB_G0272272	DDB_G0272272	NA
chr2	1472039	1474744	-	DDB_G0272148	DDB_G0272148	NA
chr2	1475387	1476202	-	DDB_G0272146	DDB_G0272146	contains a putative signal peptide
chr2	1477294	1479498	+	DDB_G0272144	DDB_G0272144	NA
chr2	1479556	1480371	-	DDB_G0272404	DDB_G0272404	NA
chr2	1480927	1481670	+	DDB_G0272142	DDB_G0272142	contains one RF-1 domain%3B similar to human ICT1 (immature colon carcinoma transcript 1 protein)
chr2	1481911	1482437	-	DDB_G0272140	DDB_G0272140	similar to mitochondrial ribosomal protein L54
chr2	1483407	1484594	+	DDB_G0272138	rab2B	similar to C. elegans rab2
chr2	1486400	1489629	+	DDB_G0272406	DDB_G0272406	NA
chr2	1489722	1492225	-	DDB_G0272134	DDB_G0272134	NA
chr2	1492518	1492590	+	DDB_G0294831	tRNA-Ile-AAU-6	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	1493180	1493863	+	DDB_G0272408	DDB_G0272408_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	1495444	1500144	+	DDB_G0272410	DDB_G0272410_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr2	1500467	1503040	-	DDB_G0272416	DDB_G0272416	no homologs in other organisms
chr2	1503629	1504469	-	DDB_G0272418	DDB_G0272418	NA
chr2	1507098	1507464	+	DDB_G0272188	DDB_G0272188	NA
chr2	1507846	1508928	-	DDB_G0272420	DDB_G0272420	expressed in pstO cells
chr2	1509530	1512862	-	DDB_G0272186	DDB_G0272186	similar to human TPR repeat protein 13 (TTC13 )
chr2	1513508	1514588	-	DDB_G0272184	DDB_G0272184	very conserved protein among bacteria and fungi%3B zinc-binding ADH%27s are dimeric or tetrameric enzymes that bind two atoms of zinc per subunit
chr2	1515537	1518014	+	DDB_G0272182	DDB_G0272182	catalyzes the reaction L-arginine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E L-citrulline %2B NH%3Csub%3E3%3C%2Fsub%3E%3B N-terminal half highly similar to bacterial argnine deiminase%2C an amidinotransferase
chr2	1518514	1519610	+	DDB_G0272180	DDB_G0272180	NA
chr2	1520067	1520570	-	DDB_G0272178	DDB_G0272178	conserved protein
chr2	1520760	1522810	+	DDB_G0272176	DDB_G0272176	conserved eukaryotic protein%3B ortholog of S. cerevisiae LAS1%2C an essential nuclear protein possibly involved in bud formation and morphogenesis
chr2	1522912	1524243	-	DDB_G0272276	gnt5	distant relative of CAZy family GT24%3B catalyzes N-linked glycosylation
chr2	1524938	1527070	-	DDB_G0272174	DDB_G0272174	NA
chr2	1528022	1529485	-	DDB_G0272422	gnt7	distant relative of CAZy family GT24%3B catalyzes N-linked glycosylation
chr2	1529992	1531455	-	DDB_G0272172	gnt6	distant relative of CAZy family GT24%3B catalyzes N-linked glycosylation
chr2	1532191	1533510	-	DDB_G0272170	gnt8	distant relative of CAZy family GT24%3B catalyzes N-linked glycosylation
chr2	1533902	1534360	+	DDB_G0272424	DDB_G0272424	similar to bacterial MarR family protein%2C a transcriptional regulator
chr2	1535421	1544549	+	DDB_G0272426	pks11_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr2	1545459	1553529	+	DDB_G0272428	pks12_ps	putative pseudogene%2C beta-ketoacyl synthase family protein
chr2	1554645	1555097	+	DDB_G0272164	DDB_G0272164	NA
chr2	1555450	1557426	-	DDB_G0272162	DDB_G0272162	NA
chr2	1558001	1559973	-	DDB_G0272278	DDB_G0272278_ps	putative pseudogene%3B similar to a Dictyostelium family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0272162%22%3E DDB_G0272162%3C%2Fa%3E
chr2	1560308	1561852	-	DDB_G0272432	DDB_G0272432	NA
chr2	1562720	1564080	+	DDB_G0272104	acpB	34 kDa subunit of heterodimeric actin capping protein cap32%2F34%3B 32 kDa subunit is encoded by acpA%3B contributes to the dynactin complex
chr2	1564450	1569426	-	DDB_G0272434	DDB_G0272434	NA
chr2	1570828	1571463	+	DDB_G0272280	DDB_G0272280	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr2	1572926	1579568	+	DDB_G0272282	DDB_G0272282	member of the AGC kinase group%3B similar to kinase domains of NDR (nuclear Dbf2-related) and MAST (microtubule-associated serine%2Fthreonine kinase)
chr2	1579848	1580576	-	DDB_G0272436	DDB_G0272436	NA
chr2	1582590	1583300	-	DDB_G0272160	DDB_G0272160	NA
chr2	1585133	1587851	+	DDB_G0272158	wrnip1	ortholog of Werner helicase-interacting protein 1%2C a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis
chr2	1588042	1589780	-	DDB_G0272156	DDB_G0272156	NA
chr2	1590421	1594059	+	DDB_G0272438	DDB_G0272438	NA
chr2	1594214	1595207	-	DDB_G0272154	DDB_G0272154	NA
chr2	1595785	1596308	+	DDB_G0272152	DDB_G0272152	contains two hydrophobic regions but is not similar to any other protein
chr2	1596579	1597666	-	DDB_G0272440	DDB_G0272440	very similar to the %3Ci%3EH. sapiens%3C%2Fi%3E tumor protein p53-inducible protein 3 (TP53I3)%3B belongs to the broader superfamily of zinc-dependent alcohol dehydrogenases
chr2	1598330	1599367	-	DDB_G0272442	DDB_G0272442	NA
chr2	1600728	1603439	+	DDB_G0272150	grlJ	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr2	1603869	1604973	-	DDB_G0272446	act34_ps	putative pseudogene%3B contains an incomplete actin domain
chr2	1605368	1606724	-	DDB_G0272288	DDB_G0272288	NA
chr2	1607842	1608972	-	DDB_G0272248	act16	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr2	1610513	1611592	+	DDB_G0272448	DDB_G0272448_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	1612117	1615296	+	DDB_G0272290	DDB_G0272290_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	1615667	1616272	-	DDB_G0272198	DDB_G0272198	NA
chr2	1616616	1621951	-	DDB_G0272450	DDB_G0272450	NA
chr2	1622396	1624930	-	DDB_G0272120	rcaA	NA
chr2	1626168	1628966	+	DDB_G0272200	DDB_G0272200	NA
chr2	1629321	1630922	+	DDB_G0272452	hapA_ps	putative pseudogene%3B very similar to hapA (Hap2 protein)
chr2	1631049	1632206	+	DDB_G0272292	DDB_G0272292_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr2	1633573	1636602	+	DDB_G0272294	DDB_G0272294	NA
chr2	1636769	1638963	-	DDB_G0272454	DDB_G0272454	NA
chr2	1639732	1644500	+	DDB_G0272456	DDB_G0272456	similar to the human amplified in breast cancer 1 (ABC1) protein
chr2	1644732	1645727	-	DDB_G0272296	sarA	similar to budding yeast Sar1%2C a 21 kDa GTP- binding protein involved in vesicular transport between the endoplasmic reticulum and the Golgi
chr2	1646887	1648400	-	DDB_G0272106	arpB	component of the Dictyostelium Arp2%2FArp3 complex%3B contributes to DdPPK2 activity%2C also described as member of the polyphosphate kinase PPK3 family
chr2	1651021	1652935	+	DDB_G0272202	DDB_G0272202	NA
chr2	1653467	1654051	+	DDB_G0272204	DDB_G0272204	NA
chr2	1655025	1656236	+	DDB_G0272118	ppp6c	NA
chr2	1656497	1657504	-	DDB_G0272458	DDB_G0272458	NA
chr2	1658418	1663847	+	DDB_G0272206	DDB_G0272206	NA
chr2	1664020	1665049	-	DDB_G0272298	DDB_G0272298	NA
chr2	1665521	1668069	-	DDB_G0272114	orfR1062	NA
chr2	1670009	1671569	+	DDB_G0272208	idhC	catalyzes the reaction isocitrate %2B NADP%2B %3D 2-oxoglutarate %2B CO2 %2B NADPH
chr2	1672253	1673699	+	DDB_G0272210	idhM	catalyzes the reaction isocitrate %2B NADP%2B %3D 2-oxoglutarate %2B CO2 %2B NADPH
chr2	1673975	1676482	-	DDB_G0272212	DDB_G0272212	NA
chr2	1678306	1680345	+	DDB_G0272214	DDB_G0272214	NA
chr2	1680676	1682415	+	DDB_G0272460	DDB_G0272460	NA
chr2	1682586	1684744	-	DDB_G0272216	aslF	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA
chr2	1684996	1687060	-	DDB_G0272300	aslE	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA
chr2	1690375	1692183	+	DDB_G0272218	DDB_G0272218	NA
chr2	1692695	1693016	-	DDB_G0272302	DDB_G0272302	NA
chr2	1693684	1696444	+	DDB_G0272220	DDB_G0272220	NA
chr2	1700447	1702624	+	DDB_G0272350	sgkC	weakly similar to sphingosine kinase
chr2	1703083	1703985	-	DDB_G0272462	qprt	catalyzes the reaction nicotinate D-ribonucleotide %2B diphosphate %2B CO%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E pyridine-2%2C3-dicarboxylate %2B 5-phospho-alpha-D-ribose 1-diphosphate
chr2	1705340	1705846	+	DDB_G0272464	DDB_G0272464	NA
chr2	1706359	1707225	-	DDB_G0272466	DDB_G0272466	NA
chr2	1707789	1710325	-	DDB_G0272468	DDB_G0272468	NA
chr2	1710917	1711411	-	DDB_G0272222	ybl1	member of the histone H2A-H2B sub-family%3B related to the NF-YB subunit of the CCAAT-binding activator NF-Y
chr2	1711679	1713171	+	DDB_G0272224	DDB_G0272224	phosphorylates NAD%2B to NADP%2B
chr2	1713237	1714892	-	DDB_G0272226	DDB_G0272226	NA
chr2	1715738	1716111	+	DDB_G0272228	DDB_G0272228	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr2	1716242	1716916	-	DDB_G0272230	DDB_G0272230	NA
chr2	1717674	1718162	-	DDB_G0272232	DDB_G0272232	contains two putative transmembrane domains
chr2	1718471	1719834	+	DDB_G0272234	pex2	ortholog of peroxin 2%2C required for peroxisome biogenesis%3B contains two putative transmembrane domains%3B mutations in human homolog cause a variety of peroxisomal disorders
chr2	1720046	1721821	+	DDB_G0272304	aspS2	catalyzes the reaction ATP %2B L-aspartate %2B tRNAAsp %3D AMP %2B diphosphate %2B L-aspartyl-tRNAAsp
chr2	1722204	1724012	+	DDB_G0272236	aspS1	catalyzes the reaction ATP %2B L-aspartate %2B tRNAAsp %3D AMP %2B diphosphate %2B L-aspartyl-tRNAAsp
chr2	1724431	1724727	+	DDB_G0272238	DDB_G0272238	NA
chr2	1725983	1727488	+	DDB_G0272240	fscD	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr2	1727972	1729506	+	DDB_G0272306	fscE	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr2	1729711	1731786	-	DDB_G0272242	cupI	similar to calcium up-regulated genes
chr2	1732877	1736050	+	DDB_G0272470	DDB_G0272470	NA
chr2	1736613	1741232	+	DDB_G0272472	DDB_G0272472	ortholog of human smoothelin%3B putative actin binding protein
chr2	1741474	1743889	-	DDB_G0272244	grlG	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr2	1745284	1746927	+	DDB_G0272474	DDB_G0272474	NA
chr2	1747963	1748470	-	DDB_G0272476	DDB_G0272476	NA
chr2	1751987	1756272	-	DDB_G0272480	DDB_G0272480	NA
chr2	1756945	1758861	+	DDB_G0272482	DDB_G0272482	NA
chr2	1758981	1760072	-	DDB_G0272246	prsB	highly similar to PRS%2C involved in nucleotide%2C histidine%2C and tryptophan biosynthesis
chr2	1760557	1762209	-	DDB_G0272484	DDB_G0272484	contains the  metal-dependent phosphohydrolase%2C HD region%3B similar to the %3Ci%3EH. sapiens%3C%2Fi%3E SAM domain and HD domain-containing protein 1 (SAMHD1)%2C but lacking the N-terminal SAM domain
chr2	1766680	1768077	+	DDB_G0272516	DDB_G0272516	NA
chr2	1768175	1770133	+	DDB_G0272534	DDB_G0272534	NA
chr2	1770352	1770679	-	DDB_G0272518	DDB_G0272518	NA
chr2	1771698	1776676	+	DDB_G0272492	DDB_G0272492	NA
chr2	1777162	1778747	-	DDB_G0272536	DDB_G0272536_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0272538%22%3EDDB_G0272538%3C%2Fa%3E 
chr2	1778862	1780622	-	DDB_G0272538	DDB_G0272538	NA
chr2	1781191	1782321	+	DDB_G0272520	act15	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr2	1783111	1785018	+	DDB_G0272490	DDB_G0272490_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0272540%22%3EDDB_G0272540%3C%2Fa%3E 
chr2	1785431	1786185	+	DDB_G0272526	sslA_ps2	putative pseudogene%3B very similar to sslA
chr2	1786441	1788252	+	DDB_G0272540	DDB_G0272540	NA
chr2	1788557	1790562	-	DDB_G0272542	prkag	non-catalytic subunit of the AMP-activated protein kinase (AMPK) complex%3B contains two CBS domains
chr2	1791640	1794521	-	DDB_G0272486	sec7	belongs to the Sec7 superfamily%3B involved in phagocytosis and cell motility%3B  pleckstrin homology (PH) domain-containing protein
chr2	1796154	1798254	-	DDB_G0272544	DDB_G0272544	similar to folate and thymidine transporters%3B contains 11 transmembrane domains
chr2	1799833	1801293	+	DDB_G0272494	DDB_G0272494	NA
chr2	1802094	1803549	+	DDB_G0272496	DDB_G0272496	NA
chr2	1803819	1805418	-	DDB_G0272498	osbD	putative ortholog of H. sapiens OSBPL8
chr2	1806966	1808204	-	DDB_G0272500	DDB_G0272500	NA
chr2	1811286	1813462	+	DDB_G0272524	malA	catalyzes the reaction (S)-malate %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %3D pyruvate %2B CO%3Csub%3E2%3C%2Fsub%3E %2B NADPH %2B H%3Csup%3E%2B%3C%2Fsup%3E%3B transcriptionally regulated by SrfA
chr2	1814324	1815406	+	DDB_G0272546	DDB_G0272546	NA
chr2	1815902	1816935	+	DDB_G0272528	DDB_G0272528	NA
chr2	1817675	1821055	+	DDB_G0272502	DDB_G0272502	NA
chr2	1821204	1821872	-	DDB_G0272504	DDB_G0272504	NA
chr2	1822376	1822588	+	DDB_G0272506	DDB_G0272506	NA
chr2	1823720	1824829	-	DDB_G0272548	DDB_G0272548_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	1825599	1825671	+	DDB_G0294833	tRNA-Gln-UUG-6	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr2	1826463	1827368	+	DDB_G0272530	DDB_G0272530	expressed in pstO cells
chr2	1827873	1832559	+	DDB_G0272532	DDB_G0272532	NA
chr2	1832689	1834610	-	DDB_G0272550	DDB_G0272550	belongs to the POT (proton-dependent oligopeptide transport) family%3B contains 12 putative transmembrane domains
chr2	1837120	1839384	+	DDB_G0272554	DDB_G0272554_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2	1841723	1842037	+	DDB_G0272508	DDB_G0272508	NA
chr2	1842421	1844193	-	DDB_G0272556	cyp519C1	NA
chr2	1844774	1845823	+	DDB_G0272510	DDB_G0272510	belongs to a gene family conserved in amoeba%3B contains a putative metal-binding domain
chr2	1846158	1848032	+	DDB_G0272522	sgkA	homolog of human Sphk1%3B phosphorylates sphinganine to sphinganine 1-phosphate
chr2	1848141	1849067	-	DDB_G0272512	DDB_G0272512	weakly similar to mammalian tenascin%3B expressed in pstAO cells
chr2	1849663	1849824	-	DDB_G0272514	DDB_G0272514	NA
chr2	1851656	1855069	+	DDB_G0272558	DDB_G0272558	NA
chr2	1856367	1857627	+	DDB_G0272909	DDB_G0272909	NA
chr2	1858373	1862398	+	DDB_G0272666	DDB_G0272666	NA
chr2	1862767	1863021	-	DDB_G0272931	timm9	conserved component of the mitochondrial intermembrane space%2C forms a complex with Timm10%2C which mediates insertion of hydrophobic proteins at the inner membrane.
chr2	1863483	1864072	+	DDB_G0272933	DDB_G0272933	the C-terminal region is conserved among hypothetical proteins in many species
chr2	1864276	1864901	+	DDB_G0272911	DDB_G0272911	NA
chr2	1865232	1868255	+	DDB_G0272935	mocos	sulfurates the molybdenum cofactor%2C which is essential for xanthine dehydrogenase and aldehyde oxidase%3B defects in the human MOCOS cause xanthinuria type II (XU-II)
chr2	1869111	1873250	+	DDB_G0272937	DDB_G0272937	NA
chr2	1873658	1874892	+	DDB_G0272726	DDB_G0272726	NA
chr2	1875234	1875548	-	DDB_G0272724	DDB_G0272724	NA
chr2	1876171	1877131	-	DDB_G0272939	DDB_G0272939	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272881%22%3E%3Ci%3EDDB_G0272881%3C%2Fi%3E%3C%2Fa%3E%3B has also similarity to hypothetical proteins in other organisms
chr2	1878915	1881083	+	DDB_G0272817	tgrA_ps4	putative pseudogene%3B immunoglobulin E-set family gene
chr2	1881173	1881921	-	DDB_G0349475	epnA_ps2	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291512%22%3E%3Ci%3EepnA%3C%2Fi%3E%3C%2Fa%3E 
chr2	1884778	1885218	-	DDB_G0349476	DDB_G0349476_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0290249%22%3EDDB_G0290249%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0282111%22%3EDDB_G0282111%3C%2Fa%3E 
chr2	1885747	1886347	-	DDB_G0272722	DDB_G0272722_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0272945%22%3EDDB_G0272945%3C%2Fa%3E 
chr2	1886873	1887127	-	DDB_G0272720	DDB_G0272720	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272947%22%3E%3Ci%3EDDB_G0272947%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272718%22%3E%3Ci%3EDDB_G0272718%3C%2Fi%3E%3C%2Fa%3E%3B contain several QPIY repeats and long stretches of histidines
chr2	1887722	1887991	-	DDB_G0272718	DDB_G0272718	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272947%22%3E%3Ci%3EDDB_G0272947%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272720%22%3E%3Ci%3EDDB_G0272720%3C%2Fi%3E%3C%2Fa%3E%3B contain several QPIY repeats and long stretches of histidines
chr2	1888648	1888929	-	DDB_G0272947	DDB_G0272947	overexpressed in aspidocytes%3B highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272718%22%3E%3Ci%3EDDB_G0272718%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272720%22%3E%3Ci%3EDDB_G0272720%3C%2Fi%3E%3C%2Fa%3E%3B contain several QPIY repeats and long stretches of histidines
chr2	1889671	1893522	-	DDB_G0272949	DDB_G0272949	NA
chr2	1894598	1896277	-	DDB_G0272951	DDB_G0272951	NA
chr2	1896679	1897925	+	DDB_G0272566	psmD14	NA
chr2	1898278	1899240	+	DDB_G0272819	hspC	32 kDa heat inducible protein
chr2	1899910	1900965	-	DDB_G0272716	DDB_G0272716	contains two putative transmembrane domains
chr2	1901589	1902665	+	DDB_G0272714	DDB_G0272714	NA
chr2	1902864	1903693	-	DDB_G0272712	mocos_ps	putative pseudogene%3B similar to parts of the molybdenum cofactor sulfurase%2C gene %3Ca href%3D%22%2Fgene%2FDDB_G0272935%22%3Emocos%3C%2Fa%3E
chr2	1904183	1905965	+	DDB_G0272953	DDB_G0272953	NA
chr2	1906038	1907405	-	DDB_G0272955	DDB_G0272955	eukaryotic phytanoyl-CoA dioxygenase is a peroxisomal enzyme catalysing the first step of phytanic acid alpha-oxidation
chr2	1907750	1908490	-	DDB_G0272957	DDB_G0272957	NA
chr2	1908716	1909587	+	DDB_G0272913	DDB_G0272913	similar to the C-terminal bacterial alanyl-tRNA synthetase domain
chr2	1909663	1910301	-	DDB_G0272710	nat9	NA
chr2	1910511	1911234	+	DDB_G0272708	DDB_G0272708	belongs to the methyltransferase superfamily%2C AML1 family%3B similar to human N6AMT2%2C S. cerevisiae AML1
chr2	1911544	1912632	-	DDB_G0272706	DDB_G0272706	belongs to a gene family conserved in amoeba
chr2	1913151	1914382	-	DDB_G0272959	cyp515A2_ps	putative pseudogene%3B related to the cytochrome P450 family
chr2	1915268	1915741	+	DDB_G0272915	colA_ps8	putative pseudogene%3B small fragment similar to the large colossin A gene  %3Ca href%3D%22%2Fgene%2FDDB_G0292696%22%3E%3Ci%3EcolA%3C%2Fi%3E%3C%2Fa%3E
chr2	1915942	1917955	-	DDB_G0272704	cyp515A1	NA
chr2	1918796	1919311	+	DDB_G0272929	isg12	NA
chr2	1919477	1919707	-	DDB_G0272702	DDB_G0272702	NA
chr2	1919957	1921446	-	DDB_G0272917	DDB_G0272917	NA
chr2	1921731	1922422	-	DDB_G0272700	DDB_G0272700	NA
chr2	1923213	1924569	+	DDB_G0272919	DDB_G0272919	contains no functional domains
chr2	1925070	1925243	+	DDB_G0272698	DDB_G0272698_ps	putative pseudogene%3B small fragment of D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0272919%22%3EDDB_G0272919%3C%2Fa%3E
chr2	1925752	1939413	+	DDB_G0272696	DDB_G0272696	NA
chr2	1939687	1942329	+	DDB_G0272961	DDB_G0272961	NA
chr2	1942697	1944250	+	DDB_G0272921	DDB_G0272921	NA
chr2	1944524	1945592	+	DDB_G0272963	DDB_G0272963	NA
chr2	1945680	1946582	+	DDB_G0272670	DDB_G0272670	NA
chr2	1946792	1948767	-	DDB_G0272965	DDB_G0272965	NA
chr2	1949614	1951836	-	DDB_G0272967	hbx4	NA
chr2	1952612	1953771	-	DDB_G0272969	psmB1	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr2	1954958	1956208	+	DDB_G0272971	DDB_G0272971	NA
chr2	1957484	1959368	+	DDB_G0272694	gacH	NA
chr2	1960823	1962031	+	DDB_G0272692	DDB_G0272692	NA
chr2	1962368	1962949	+	DDB_G0272821	DDB_G0272821	NA
chr2	1963629	1968170	+	DDB_G0272973	DDB_G0272973	NA
chr2	1968947	1971369	+	DDB_G0272690	DDB_G0272690	NA
chr2	1974054	1976440	+	DDB_G0272975	DDB_G0272975	NA
chr2	1976953	1980006	+	DDB_G0272977	DDB_G0272977	NA
chr2	1980098	1980997	-	DDB_G0272688	DDB_G0272688	NA
chr2	1981430	1983155	-	DDB_G0272979	DDB_G0272979	NA
chr2	1983840	1985207	+	DDB_G0272686	DDB_G0272686	similar to D. purpureum protein
chr2	1985270	1986069	-	DDB_G0272684	qdpr	ortholog of QDPR%2C which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin (a 5%2C6%2C7%2C8-tetrahydropteridine %2B NAD(P)%2B %3D a 6%2C7-dihydropteridine %2B NAD(P)H %2B H%2B)%2C the last step of tetrahydrobiopterin (BH4) recycling in higher eukaryotes%2C an essential cofactor
chr2	1986849	1987547	+	DDB_G0272835	plip	phosphoinositide phosphatase with low specific activity compared to other known phosphoinositide phosphatases%3B can dephosphorylate several phosphoinositide substrates%2C with a preference for PI(5)P%3B constitutively expressed%3B putative ortholog of H. sapiens EPM2A%2C involved in myoclonic epilepsy of Lafora
chr2	1987848	1991280	+	DDB_G0272682	DDB_G0272682	partial similarity to cry34%2C the %3Ci%3EBacillus thuringiensis%3C%2Fi%3E proteinaceous crystal and insecticidal toxin%2C formed during sporulation%3B contains an endonuclease%2Fexonuclease%2Fphosphatase domain which is found in proteins such as magnesium dependent endonucleases and phosphatases involved in intracellular signalling
chr2	1992058	1993555	+	DDB_G0272923	DDB_G0272923	NA
chr2	1994416	2002148	+	DDB_G0272981	pks13	putative type I iterative polyketide synthase
chr2	2003225	2006926	+	DDB_G0272680	DDB_G0272680	protein phosphatase 2C is a serine%2Fthreonine specific protein phosphatase with broad substrate specificity and dependent on divalent cations (mainly manganese and magnesium) for its activity
chr2	2007612	2010203	+	DDB_G0272678	DDB_G0272678	NA
chr2	2010405	2012223	-	DDB_G0272983	DDB_G0272983	contains one DnaJ N-terminal domain and one MYND-type zinc finger domain%3B contains 8 putative transmembrane domains
chr2	2012543	2015571	+	DDB_G0272985	vps54	putative ortholog of S. cerevisiae VPS54%2C component of the GARP (Golgi-associated retrograde protein) complex
chr2	2015699	2017900	-	DDB_G0272823	DDB_G0272823	NA
chr2	2019070	2020303	-	DDB_G0272825	rps4	protein component of the small (40S) ribosomal subunit%3B highly expressed in vegetative cells and in early development
chr2	2020830	2025240	+	DDB_G0272987	irlA	the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy
chr2	2025586	2027977	-	DDB_G0272989	vps5	putative ortholog of mammalian sorting nexin and S. cerevisiae VPS5%2C a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport
chr2	2028796	2032812	-	DDB_G0272925	gacU	NA
chr2	2034015	2036935	-	DDB_G0272991	exoc7	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr2	2037250	2039714	+	DDB_G0272676	sf3a1	subunit of the splicing factor SF3A required for spliceosome assembly
chr2	2041459	2047835	+	DDB_G0272674	DDB_G0272674	NA
chr2	2048228	2048593	+	DDB_G0272672	DDB_G0272672	NA
chr2	2048952	2049699	-	DDB_G0272827	cbpI	expressed in prespore cells%3B contains only 3 EF hands and does not bind calcium
chr2	2051969	2055385	-	DDB_G0272993	DDB_G0272993	NA
chr2	2056744	2057388	+	DDB_G0272871	ssu72	ortholog of human and S. cerevisiae SSU72 (suppressor of SUA7 protein 2)%3B S. cerevisiae SSU72 is involved in several roles%2C including 3%27 end formation of pre-mRNA and snoRNAs%2C and dephosphorylation of RNA polymerase II%3B the D. discoideum homolog of yeast SUA7 is %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2F%09DDB_G0290929%22%3E %3Ci%3Egtf2b%3C%2Fi%3E %3C%2Fa%3E
chr2	2057584	2060371	-	DDB_G0272869	sun1	localizes to the inner and outer nuclear membrane%2C mediates the attachment between centrosome and nucleus%2C associates the centromere cluster with the centrosome%2C and stabilizes the genome during mitosis%3B contains one transmembrane domain
chr2	2061113	2064834	+	DDB_G0272995	DDB_G0272995	NA
chr2	2065311	2067345	+	DDB_G0272867	argS1	catalyzes the reaction ATP %2B L-arginine %2B tRNAArg %3D AMP %2B diphosphate %2B L-arginyl-tRNAArg
chr2	2067475	2069478	-	DDB_G0272865	DDB_G0272865	NA
chr2	2069719	2071154	+	DDB_G0272863	DDB_G0272863	NA
chr2	2071499	2071747	-	DDB_G0272861	cosA	belongs to the costars family%3B similar to the C terminal region of mammalian striated muscle activator of Rho signaling
chr2	2072143	2081242	-	DDB_G0272859	pks14	putative type I iterative polyketide synthase
chr2	2081848	2085389	-	DDB_G0272997	DDB_G0272997	NA
chr2	2085728	2087495	-	DDB_G0272829	DDB_G0272829	NA
chr2	2088080	2090796	-	DDB_G0272999	pkd2	putative Ca2%2B channel%3B similar to metazoan polycystin-2 (PKD2)%3B defects in the human PKD2 causes polycystic kidney disease autosomal dominant type 2 (ADPKD2) characterized by progressive formation and enlargement of cysts in both kidneys%3B contains 6 putative transmembrane domains
chr2	2092080	2094128	+	DDB_G0272748	DDB_G0272748	NA
chr2	2094380	2095226	-	DDB_G0272857	rapB	NA
chr2	2096672	2097355	+	DDB_G0272750	DDB_G0272750_ps	putative pseudogene%3B fragment%3B similar to a D. discoideum patatin gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0283551%22%3EDDB_G0283551%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283595%22%3EDDB_G0283595%3C%2Fa%3E
chr2	2097426	2098173	-	DDB_G0272752	DDB_G0272752	contains a C2 calcium%2Flipid-binding region (CaLB)
chr2	2098484	2099242	-	DDB_G0272855	DDB_G0272855	NA
chr2	2099808	2101322	-	DDB_G0272754	gsr	converts oxidized glutathione to reduced glutathione
chr2	2102038	2102926	-	DDB_G0272831	psmA7	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr2	2103930	2104345	-	DDB_G0272756	csbC	component of contact site B
chr2	2105702	2106114	-	DDB_G0272562	csbB	component of contact site B
chr2	2107219	2107628	-	DDB_G0272833	csbA	component of contact site B
chr2	2108163	2111066	+	DDB_G0272758	chtf18	in %3Ci%3ES. cerevisiae%3C%2Fi%3E essential for the fidelity of chromosome transmission and component of the RFC complex%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E CTF18 (%22chromosome-transmission-fidelity-18%22) was originally identified as a yeast gene required for the establishment of sister chromatid cohesion. Newer work in both yeasts and mammalian cells shows that CTF18 interacts with DCC1 (%22defective in chromosome cohesion-1%22) and CTF8. Together with the RFC subunits 2-5 they form a complex which shows both PCNA-loading and PCNA-unloading activity in vitro. A recent paper speculates that the complex is required on the lagging strand to allow the replication fork to pass through cohesin rings%2C which are established around the DNA prior to replication [see Farina et al%2C Journal of Biological Chemistry 283%2C 20925-36 (2008)%2C and references cited there].%3Cbr%3E Dictyostelium has a clear ortholog of DCC1%2C and a possible ortholog of CTF8 (DDB_G0287975) (E Value 3e-09 by direct comparison with human CTF8). All three of these genes are strongly overexpressed in a Dictyostelium strain in which the retinoblastoma-like gene rblA has been disrupted (CTF18%2C fivefold%3B DCC1%2C 11-fold%3B CTF8%2C 25fold) (Doquang et al%2C in preparation). Most genes with roles in cell cycle progression are overexpressed in this strain. The overexpression factors are similar to those (5 to 15-fold) for other genes whose products are required at the replication fork%2C such as polymerases alpha%2C delta and epsilon%2C and PCNA itself. %3Ci%3EHarry MacWilliams%2C November 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FChtf18%22%3E There is more information on the wiki page%3C%2Fa%3E 
chr2	2111171	2113956	-	DDB_G0272760	mcm6	similar to MCM6%2C a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
chr2	2114192	2114680	-	DDB_G0272853	DDB_G0272853	NA
chr2	2117004	2117638	-	DDB_G0272762	DDB_G0272762	NA
chr2	2118091	2118531	+	DDB_G0273003	snrpD3	NA
chr2	2121552	2123626	+	DDB_G0273005	DDB_G0273005	NA
chr2	2123898	2126411	-	DDB_G0294407	helF	DEAH-box helicase and putatibe dsRNA binding protein acting as a nuclear suppressor of RNAi
chr2	2126877	2136401	-	DDB_G0273007	pks15	putative type I iterative polyketide synthase
chr2	2137821	2143410	+	DDB_G0272765	DDB_G0272765	NA
chr2	2144128	2145019	-	DDB_G0272767	DDB_G0272767	NA
chr2	2145765	2148199	+	DDB_G0272769	DDB_G0272769	NA
chr2	2148504	2149959	+	DDB_G0272839	DDB_G0272839	has a short region of similarity to aprataxin%2C a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia
chr2	2150157	2151857	-	DDB_G0273009	DDB_G0273009	NA
chr2	2152302	2153897	-	DDB_G0273011	DDB_G0273011_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0273009%22%3EDDB_G0273009%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0280379%22%3EDDB_G0280379%3C%2Fa%3E
chr2	2154360	2158488	-	DDB_G0272771	wdr7	putative ortholog of H. sapiens WDR7%2C also known as TGF-beta resistance-associated protein (TRAG) and rabconnectin-3 beta
chr2	2159393	2160010	+	DDB_G0272773	DDB_G0272773	contains a predicted signal peptide%3B there are two similar genes in D. discoideum
chr2	2160250	2162043	-	DDB_G0273013	uglB	DNA repair enzyme that excises uracil residues from the DNA which can arise from misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
chr2	2162746	2164524	-	DDB_G0272775	anapc8	NA
chr2	2164739	2167055	+	DDB_G0272777	DDB_G0272777	member of the same super family as valosin-containing protein (VCP) and CDC48%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0272777 appears to be the Dicty-specific%2C AAA-ATPase related cdc48 (cdcD) in Dicty and other organisms. When %22blasted out%22 DDB_G0272777 hits cdc48 and cdc48-related proteins in many organisms%2C but when these are blasted back to Dicty%2C cdcD rather than DDB_G0272777 is always the first hit. Cdc48 is an ubiquitin-associated chaperone which is involved in the degradation of a variety of cellular proteins%2C particularly proteins trapped in macromolecular structures%2C which must be mobilized for degradation. Cdc48 is ascribed a major role in the ERAD (ER-associated degradation) pathway in which proteins that fail to fold properly are retransported to the cytosol and degraded by the ubiquitin-proteasome pathway.%3Cbr%3E DDB G0272777 is fourfold overexpressed (p%3C10e-10) in a Dicty strain lacking the retinoblastoma-like gene rblA (Doquang et al%2C in preparation). Most genes involved in DNA replication%2C centrosome duplication and mitosis are overexpressed in this strain%2C typically by factors from 5x to 20x. This supports the idea that DDB G0272777 is involved in Dicty cell cycle progression. CdcD%2C by constrast%2C shows virtually no overpression in the rblA disruptant (induction factor in mutant ca 1%2C1). An interesting possibility is that DDB_G0272777 has diverged from cdcD and specialized for mitotic function%2C while the nonmitotic functions of cdc48 have been taken over by cdcD. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0272777%22%3E There is more information on the wiki page%3C%2Fa%3E
chr2	2167082	2170050	-	DDB_G0272851	DDB_G0272851_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr2	2170341	2171350	-	DDB_G0272781	pmmB	catalyzes the reaction alpha-D-mannose 1-phosphate %3C%3D%3E D-mannose 6-phosphate
chr2	2172067	2173694	+	DDB_G0272783	rliA	twelve transmembrane domain protein that may act as a transporter%3B repressed after %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr2	2173913	2175949	-	DDB_G0272785	DDB_G0272785	similar to human AOAH (acyloxyacyl hydrolase)%3B removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides%3B contains a predicted signal peptide%3B contains 1 saposin B-type domain
chr2	2176582	2177922	-	DDB_G0272787	sds	catalyzes the reaction L-serine %3D pyruvate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr2	2178487	2179119	-	DDB_G0272789	rlp24	ortholog of the mammalian C15orf15 gene and the S. cerevisiae RLP24 protein%2C which is involved in the biogenesis of the 60S ribosomal subunit and at the end of biogenesis is likely to be exchanged for its ribosomal homologue%2C rpl24
chr2	2179680	2183684	-	DDB_G0272849	DDB_G0272849	contains two putative EGF repeats%2C an N-terminal signal sequence and a C-terminal transmembrane domain%3B thus this seems to be an extracellular protein that is anchored in the membrane
chr2	2184460	2186663	-	DDB_G0348736	DDB_G0348736_ps	putative pseudogene%3B similar to the large family of EGF repeat-containing proteins%2C including neighboring gene %3Ca href%3D%22%2Fgene%2FDDB_G0272849%22%3EDDB_G0272849%3C%2Fa%3E
chr2	2187983	2188403	+	DDB_G0273057	csbD_ps	putative pseudogene%3B similar to csbA%2C csbB%2C and csbC
chr2	2190439	2193253	+	DDB_G0272845	DDB_G0272845	NA
chr2	2194537	2201313	+	DDB_G0272837	ifkA	eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase%3B putative protein serine%2Fthreonine kinase%3B contains two kinase domains and a HisRS domain%3B N-terminal kinase domain related to STE group%3B C-terminal kinase domain related to GCN2  subfamily
chr2	2205077	2206935	+	DDB_G0349497	DDB_G0349497_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271638%22%3EDDB_G0271638%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271636%22%3EDDB_G0271636%3C%2Fa%3E 
chr2	2207279	2211697	+	DDB_G0349499	DDB_G0349499	NA
chr2	2212329	2213613	-	DDB_G0272815	cprE	NA
chr2	2214393	2215610	-	DDB_G0272728	DDB_G0272728	bears no similarity to any other gene in public databases
chr2	2216835	2217926	+	DDB_G0272813	cdk1	similar to CDK1 and CDK2 cell cycle CAK (CDK-activating kinase) kinases%3B predicted to activate S%2FG2 cyclins cyclin A%2C B and D
chr2	2218228	2219580	-	DDB_G0272730	alg2	CAZy family GT4%3B catalyzes N-linked mannosylation
chr2	2220282	2221393	+	DDB_G0272732	emg1	ortholog of S. cerevisiae and H. sapiens EMG1%2C involved in 40S ribosome biogenesis
chr2	2221948	2222524	+	DDB_G0272734	DDB_G0272734	NA
chr2	2222634	2225574	-	DDB_G0272736	tgrN1	contains a predicted signal peptide and a C-terminal transmembrane domain
chr2	2227186	2228208	+	DDB_G0272738	iunH	catalyzes the reaction N-D-ribosylpurine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E purine %2B D-ribose
chr2	2228582	2229156	+	DDB_G0272740	DDB_G0272740	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0272740 is similar to histone2a-related transcription factors of the Hap5%2FCBF%2FNF-Y family%2C which bind to the subsequence CCAAT and is threefold upregulated (p%3C3E-7) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). Most genes associated with S-phase or mitosis are upregulated in this strain. This is is consistent with the idea that factors of the the Hap5%2FCBF%2FNF-Y factors are involved in cell cycle progression in Dictyostelium as they are in animal cells. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E%3Cbr%3E Closer examination of the blast results suggests that this gene does NOT code for an NF-Y subunit. Real orthologs to DDB_G0272740 do seem to occur in some fungi%2C for instance Aspergillis and Ajellomyces%2C although there are none in budding yeast. Insects also have a protein that is much more closely related to DDB_G0272740 than it is to nfyC%3B it is called chrac-16 and is a component of the chromatin accessibility complex (Corona et al%2C EMBO Journal 19%2C 3049-3059 (2000)). Chrac-16 is expressed mainly in the first 6 hours of Drosophila development%2C corresponding to cleavage through germ band elongation%3B this is when most cell divisions occur. In later stages of fly development%2C when endoreduplication occurs but no mitosis%2C chrac-16 epxression is not detectable. This is consistent a role of chrac-16%2C and thus possibly DDB_G0272740%2C in the regulation of mitotic genes. %3Ci%3EHarry MacWilliams%2C March 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0272740%22%3E There is more information on the wiki page%3C%2Fa%3E
chr2	2229610	2230747	+	DDB_G0272742	DDB_G0272742	NA
chr2	2231078	2232793	+	DDB_G0272843	DDB_G0272843	NA
chr2	2232918	2234810	-	DDB_G0272811	wasB	contains a WASP-C domain and a WH2 actin-binding motif%3B plays a role in the regulation of F-actin polymerization and pseudopod formation
chr2	2236569	2237975	+	DDB_G0273017	DDB_G0273017	catalyzes the reaction isocitrate %3C%3D%3E glyoxylate %2B succinate
chr2	2238625	2238986	+	DDB_G0272744	DDB_G0272744	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr2	2239128	2240267	-	DDB_G0272746	DDB_G0272746	NA
chr2	2241089	2242843	+	DDB_G0272841	DDB_G0272841	belongs to the metallophosphoesterase superfamily%3B similar to A. thaliana PAP6 (purple acid phosphatase)%3B contains a predicted signal peptide and putative C-terminal transmembrane domain
chr2	2243539	2245192	+	DDB_G0272660	serS	catalyzes the reaction ATP %2B L-serine %2B tRNASer %3D AMP %2B diphosphate %2B L-seryl-tRNASer
chr2	2245384	2245866	-	DDB_G0273019	DDB_G0273019_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0293012%22%3EDDB_G0293012%3C%2Fa%3E
chr2	2246849	2247448	+	DDB_G0272662	DDB_G0272662	dual specificity phosphatases remove phosphate groups from tyrosine and serine%2Fthreonine residues
chr2	2247692	2248940	-	DDB_G0272668	ppr2	regulatory subunit 2 of the protein serine%2Fthreonine phosphatase 4%2C PPC4 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272116%22%3E%3Ci%3Eppp4C%3C%2Fi%3E%3C%2Fa%3E)
chr2	2249594	2250128	+	DDB_G0272664	DDB_G0272664	NA
chr2	2251460	2253406	+	DDB_G0272809	DDB_G0272809	NA
chr2	2253643	2255760	-	DDB_G0272652	cyp525A1	NA
chr2	2255996	2256334	-	DDB_G0272654	sigN25	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B expressed in pstAO cells
chr2	2257063	2257416	+	DDB_G0273021	sigN5	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family
chr2	2257906	2258602	-	DDB_G0273023	sigN2	expressed in prestalk cells and stalk cells%3B member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family
chr2	2258985	2259337	+	DDB_G0272656	sigN4	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family
chr2	2259874	2260210	-	DDB_G0272658	sigN1	expressed at post-aggregation stage%3B regulated by the MADS-box transcription factor SrfA during the slug stage of development%3B member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family
chr2	2260937	2261314	+	DDB_G0272927	sigN3	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family
chr2	2262117	2262432	+	DDB_G0273025	sigN105-1	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B there is a second copy of this gene%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB0238205%22%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274097%22%3E%3Ci%3EDDB_G0274097%3C%2Fi%3E%3C%2Fa%3E%3C%2Fb%3E
chr2	2268088	2270045	+	DDB_G0272791	rsc11-1	conserved protein of unknown function%3B there is a second copy of this gene%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0295699%22%3E%3Ci%3Ersc11-2%3C%2Fi%3E%3C%2Fb%3E
chr2	2270218	2271796	-	DDB_G0272624	adrm1-1	interacts with the phg2 kinase%3B pathway plays a role in the transition from growth to differentiation%3B%3C%2Fbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274093%22%3E%3Ci%3Eadrm1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2272326	2273717	-	DDB_G0272626	DDB_G0272626	NA
chr2	2276143	2276777	+	DDB_G0272793	DDB_G0272793	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274089%22%3EDDB_G0274089%3C%2Fa%3E
chr2	2277326	2278681	+	DDB_G0272873	DDB_G0272873	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274087%22%3EDDB_G0274087%3C%2Fa%3E
chr2	2278778	2279897	-	DDB_G0272628	DDB_G0272628	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants%3B%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274085%22%3E%3Ci%3EDDB_G0274085%3C%2Fi%3E%3C%2Fa%3E
chr2	2280592	2281393	-	DDB_G0272630	DDB_G0272630	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274083%22%3EDDB_G0274083%3C%2Fa%3E
chr2	2282062	2282845	+	DDB_G0272632	DDB_G0272632	catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274081%22%3E%3Ci%3EDDB_G0274081%3C%2Fi%3E%3C%2Fa%3E
chr2	2283023	2284051	-	DDB_G0272634	dohh-1	ortholog of H. sapiens DOHH%2C that catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine%2C an essential post-translational modification only found in mature eIF5A factor%3B the first reaction is catalyzed by Dhps%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274079%22%3E%3Ci%3Edohh-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2284317	2288059	-	DDB_G0273051	drnA-1	similar to the mammalian Dicer protein%2C an RNase III protein that converts long dsRNA (double-stranded RNA) into siRNA (small interfering RNA)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274077%22%3E%3Ci%3EdrnA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2288541	2293097	-	DDB_G0273053	DDB_G0273053	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274075%22%3E%3Ci%3EDDB_G0274075%3C%2Fi%3E%3C%2Fa%3E 
chr2	2293392	2294528	-	DDB_G0273027	DDB_G0273027	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274073%22%3EDDB_G0274073%3C%2Fa%3E
chr2	2294733	2295182	-	DDB_G0273029	DDB_G0273029	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274071%22%3EDDB_G0274071%3C%2Fa%3E
chr2	2295735	2296955	+	DDB_G0272636	DDB_G0272636	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274069%22%3EDDB_G0274069%3C%2Fa%3E
chr2	2297189	2300839	-	DDB_G0272638	DDB_G0272638	PIP5K catalyze the formation of phosphoinositol-4%2C5-bisphosphate via the phosphorylation of phosphatidylinositol-4-phosphate%2C a precursor in the phosphinositide signaling pathway%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274067%22%3E%3Ci%3EDDB_G0274067%3C%2Fi%3E%3C%2Fa%3E
chr2	2304323	2305150	-	DDB_G0272640	DDB_G0272640	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274065%22%3EDDB_G0274065%3C%2Fa%3E
chr2	2307287	2308849	+	DDB_G0272642	DDB_G0272642	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274063%22%3E%3Ci%3EDDB_G0274063%3C%2Fi%3E%3C%2Fa%3E
chr2	2309231	2310703	+	DDB_G0272644	DDB_G0272644	contains 3 FNIP repeats%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274061%22%3EDDB_G0274061%3C%2Fa%3E
chr2	2310809	2311240	-	DDB_G0272568	cofC-1	a new member of the cofilin family%2C specifically expressed during aggregation%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274059%22%3E%3Ci%3EcofC-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2311642	2312058	-	DDB_G0272646	cofD-1	very similar to cofC and similar to cofA%2C a 15 kDa protein with actin filament severing activity%3B contains an actin-binding%2C cofilin%2Ftropomyosin type domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?dictybaseid%3DDDB0238845 %22%3E%3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274057%22%3E%3Ci%3EcofD-2%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E%3C%2Fa%3E
chr2	2312521	2313388	+	DDB_G0272648	DDB_G0272648	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274055%22%3EDDB_G0274055%3C%2Fa%3E 
chr2	2313660	2314055	-	DDB_G0272650	DDB_G0272650	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274053%22%3EDDB_G0274053%3C%2Fa%3E
chr2	2314701	2316520	-	DDB_G0272875	cpnB-1	Ca(2%2B)-dependent phospholipid-binding protein%3B contains two C2 domains and a VWFA domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274051%22%3E%3Ci%3EcpnB-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2317791	2319467	+	DDB_G0272877	DDB_G0272877	contains 4 coiled-coil domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274049%22%3EDDB_G0274049%3C%2Fa%3E
chr2	2319732	2320089	-	DDB_G0272879	DDB_G0272879	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274047%22%3EDDB_G0274047%3C%2Fa%3E 
chr2	2321351	2322092	-	DDB_G0272795	3B-1	expressed in prespore cells%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274045%22%3E%3Ci%3E3B-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2322900	2323694	+	DDB_G0273031	DDB_G0273031	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274043%22%3EDDB_G0274043%3C%2Fa%3E
chr2	2328058	2332874	+	DDB_G0273033	DDB_G0273033	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274041%22%3E%3Ci%3EDDB_G0274041%3C%2Fi%3E%3C%2Fa%3E
chr2	2332988	2333942	-	DDB_G0272881	DDB_G0272881	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272939%22%3E%3Ci%3EDDB_G0272939 %3C%2Fi%3E%3C%2Fa%3E%3B has also similarity to hypothetical proteins in other organisms%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274039%22%3E%3Ci%3EDDB_G0274039%3C%2Fi%3E%3C%2Fa%3E 
chr2	2334392	2335249	+	DDB_G0272606	DDB_G0272606	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274037%22%3EDDB_G0274037%3C%2Fa%3E 
chr2	2335396	2338175	-	DDB_G0272608	stip-1	conserved protein%2C ortholog of the %3Ci%3ED. melanogaster%3C%2Fi%3E sip1 gene (septin interaction protein) and to the %3Ci%3EH. sapiens%3C%2Fi%3E tuftelin-interacting protein 11 (TFIP11)%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB0266882%22%3E%3Ci%3Estip-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2339145	2341327	-	DDB_G0273035	fslM-1	has similarity to G-protein-coupled receptors%3B predicted to have 7 transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274033%22%3E%3Ci%3EfslM-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2342908	2345261	-	DDB_G0272610	DDB_G0272610	weakly similar to glycoproteins GP138A-D and gp130%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274031%22%3E%3Ci%3EDDB_G0274031%3C%2Fi%3E%3C%2Fa%3E
chr2	2346179	2350046	+	DDB_G0273037	ptcJ-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274029%22%3EptcJ-2%3C%2Fa%3E
chr2	2350685	2352527	+	DDB_G0272612	DDB_G0272612	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274027%22%3EDDB_G0274027%3C%2Fa%3E
chr2	2352791	2353344	-	DDB_G0272614	DDB_G0272614	similar to the THAP domain in the mammalian THAP domain-containing protein 4%3B underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants%3B%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274025%22%3E%3Ci%3EDDB_G0274025%3C%2Fi%3E%3C%2Fa%3E
chr2	2353564	2354565	-	DDB_G0272560	capA-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274023%22%3E%3Ci%3EcapA-2%3C%2Fi%3E%3C%2Fa%3E %3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with cap%2C the cyclase-associated protein protein
chr2	2355911	2357213	+	DDB_G0272616	rnrB-1	catalyzes the reaction 2%27-deoxyribonucleoside diphosphate %2B thioredoxin disulfide %2B H%3Csub%3E2%3C%2Fsub%3EO %3D ribonucleoside diphosphate %2B reduced thioredoxin%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274021%22%3E%3Ci%3ErnrB-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2357975	2360086	+	DDB_G0272618	tkt-1	catalyzes the reaction D-ribose-5-phosphate %2B D-xylulose-5-phosphate %3C%3D%3E D-sedoheptulose-7-phosphate %2B D-glyceraldehyde-3-phosphate%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274019%22%3E%3Ci%3Etkt-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2360286	2361824	+	DDB_G0273039	iptC-1	IPP transferases modify both cytoplasmic and mitochondrial tRNAs at A(37) to give isopentenyl A(37)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274017%22%3E%3Ci%3EiptC-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2361855	2363062	-	DDB_G0272883	ksrA-1	catalyzes the reduction of sphinganine to 3-dehydrosphinganine in glycosphingolipid metabolism%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274015%22%3E%3Ci%3EksrA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2363352	2363876	+	DDB_G0272620	DDB_G0272620	similar to human HSBP1%3B HSBP1 is a negative regulator of the heat shock response%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274013%22%3E%3Ci%3EDDB_G0274013%3C%2Fi%3E%3C%2Fa%3E
chr2	2364367	2366904	+	DDB_G0272885	fslJ-1	identified as a suppressor of smlA null mutant cnr1%3B putative cell number regulator%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274011%22%3E%3Ci%3EfslJ-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2367362	2368975	-	DDB_G0272622	DDB_G0272622	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0274009%22%3EDDB_G0274009%3C%2Fa%3E
chr2	2368968	2371359	-	DDB_G0272797	DDB_G0272797	similar to cyclin dependent protein kinases%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274007%22%3E%3Ci%3EDDB_G0274007%3C%2Fi%3E%3C%2Fa%3E
chr2	2374895	2378827	-	DDB_G0272578	ap3b-1	there is a second copy of this gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274003%22%3E%3Ci%3Eap3b-2%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr2	2379312	2380124	-	DDB_G0272889	surf1-1	ortholog of SURF1%2C encoding a factor involved in the biogenesis of cytochrome c oxidase%2C mutated in Leigh syndrome%3B there is a second copy of this gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274001%22%3E%3Ci%3Esurf1-2%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr2	2380443	2381344	+	DDB_G0272580	DDB_G0272580	similar to human RWDD1%2C S. cerevisiae GIR2%3B S. cerevisiae GIR2 binds to and regulates the expression of GTP-binding protein DRG2%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273999%22%3E%3Ci%3EDDB_G0273999%3C%2Fi%3E%3C%2Fa%3E
chr2	2381533	2382876	-	DDB_G0273041	DDB_G0273041	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273997%22%3EDDB_G0273997%3C%2Fa%3E
chr2	2383418	2384220	-	DDB_G0272799	icmA-1	prenylcysteine methyltransferase%2C carries out carboyxl methylation of cleaved eukaryotic proteins that terminate in a CaaX motif such as NE81 (lmnB)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273995%22%3E%3Ci%3EicmA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2385363	2386907	+	DDB_G0272582	maoB-1	catalyzes the reaction RCH%3Csub%3E2%3C%2Fsub%3ENH%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3D RCHO %2B ammonia %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3B acts on primary amines%2C as well as on some secondary and tertiary amines%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273993%22%3E%3Ci%3EmaoB-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2388472	2389978	+	DDB_G0272584	maoC-1	catalyzes the reaction RCH%3Csub%3E2%3C%2Fsub%3ENH%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3D RCHO %2B ammonia %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3B acts on primary amines%2C as well as on some secondary and tertiary amines%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273991%22%3E%3Ci%3EmaoC-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2390435	2391289	+	DDB_G0272586	DDB_G0272586	expressed in prespore cells%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273989%22%3E%3Ci%3EDDB_G0273989%3C%2Fi%3E%3C%2Fa%3E
chr2	2391829	2392464	+	DDB_G0272891	DDB_G0272891_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0272586%22%3EDDB_G0272586%3C%2Fa%3E%3B there is a second copy of this pseudogene %3Ca href%3D%22%2Fgene%2FDDB_G0273987%22%3E%3Ci%3EDDB_G0273987%3C%2Fi%3E%3C%2Fa%3E
chr2	2392581	2394869	-	DDB_G0272801	DDB_G0272801	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273985%22%3EDDB_G0273985%3C%2Fa%3E
chr2	2395262	2396133	-	DDB_G0272893	rpl15-1	protein component of the large (60S) ribosomal subunit%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273983%22%3E%3Ci%3Erpl15-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2396788	2397192	+	DDB_G0272588	dpm2-1	highly conserved protein involved in GPI biosynthesis%3B forms a complex with DPM1 and DPM3%3B regulates the biosynthesis of dolichol-phosphate-mannose%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273981%22%3E%3Ci%3Edpm2-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2397564	2398683	+	DDB_G0272564	psmD8-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273979%22%3E%3Ci%3EpsmD8-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2398894	2399443	-	DDB_G0272590	srp14-1	component of the signal recognition particle (SRP)%2C which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulum%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273977%22%3E%3Ci%3Esrp14-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2400265	2404860	+	DDB_G0272592	DDB_G0272592	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273975%22%3E%3Ci%3EDDB_G0273975%3C%2Fi%3E%3C%2Fa%3E
chr2	2405347	2406940	-	DDB_G0272594	DDB_G0272594_ps	putative pseudogene%3B very similar to the putative importin subunit alpha C gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0277993%22%3EDDB_G0277993%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273973%22%3EDDB_G0273973%3C%2Fa%3E
chr2	2408163	2408393	+	DDB_G0272803	DDB_G0272803	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273969%22%3EDDB_G0273969%3C%2Fa%3E
chr2	2408810	2413313	+	DDB_G0272805	DDB_G0272805	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273967%22%3E%3Ci%3EDDB_G0273967%3C%2Fi%3E%3C%2Fa%3E
chr2	2414215	2418740	+	DDB_G0272897	DDB_G0272897	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273965%22%3E%3Ci%3EDDB_G0273965%3C%2Fi%3E%3C%2Fa%3E
chr2	2419091	2419482	-	DDB_G0272596	DDB_G0272596	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273963%22%3EDDB_G0273963%3C%2Fa%3E
chr2	2420797	2425625	+	DDB_G0273043	DDB_G0273043	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273961%22%3E%3Ci%3EDDB_G0273961%3C%2Fi%3E%3C%2Fa%3E
chr2	2425859	2427472	-	DDB_G0272598	DDB_G0272598_ps	putative pseudogene%2C similar to to a large family of EGF like domain-containing proteins%3B there is a second copy of this pseudogene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273959%22%3E%3Ci%3EDDB_G0273959_ps%3C%2Fi%3E%3C%2Fa%3E
chr2	2429907	2434759	-	DDB_G0272901	DDB_G0272901	conserved Dictyostelium protein%3B contains a weak putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273955%22%3E%3Ci%3EDDB_G0273955%3C%2Fi%3E%3C%2Fa%3E
chr2	2435526	2437553	+	DDB_G0272903	DDB_G0272903	hypothetical protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273953%22%3E%3Ci%3EDDB_G0273953%3C%2Fi%3E%3C%2Fa%3E
chr2	2437736	2442458	-	DDB_G0272600	DDB_G0272600	ortholog of human HPS5%3B mutations in human HPS5 have been linked to Hermansky-Pudlak syndrome 5%3B contains a putative RING Zn finger%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273951%22%3E%3Ci%3EDDB_G0273951%3C%2Fi%3E%3C%2Fa%3E
chr2	2443179	2447136	+	DDB_G0272807	DDB_G0272807	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273949%22%3EDDB_G0273949%3C%2Fa%3E
chr2	2447280	2448933	+	DDB_G0272602	DDB_G0272602	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273947%22%3EDDB_G0273947%3C%2Fa%3E
chr2	2449037	2450836	-	DDB_G0272604	cyp508A2-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273945%22%3E%3Ci%3Ecyp508A2-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2451402	2453414	-	DDB_G0273045	cyp508A1-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273943%22%3E%3Ci%3Ecyp508A1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2454253	2456119	-	DDB_G0273047	cyp508A3-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273941%22%3E%3Ci%3Ecyp508A3-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2456931	2457617	-	DDB_G0272570	DDB_G0272570	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273939%22%3EDDB_G0273939%3C%2Fa%3E
chr2	2458351	2458935	-	DDB_G0272572	DDB_G0272572	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273937%22%3EDDB_G0273937%3C%2Fa%3E
chr2	2459564	2460318	-	DDB_G0272905	rabF1-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273935%22%3E%3Ci%3ErabF1-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2461135	2462186	-	DDB_G0273049	DDB_G0273049	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273933%22%3EDDB_G0273933%3C%2Fa%3E
chr2	2463205	2464268	-	DDB_G0272907	DDB_G0272907_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0273933%22%3EDDB_G0273933%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0273049%22%3EDDB_G0273049%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273929%22%3EDDB_G0273929_ps%3C%2Fa%3E
chr2	2466189	2466914	-	DDB_G0272576	DDB_G0272576	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273927%22%3EDDB_G0273927%3C%2Fa%3E
chr2	2469557	2470314	+	DDB_G0273153	DDB_G0273153	weakly similar to glutathione S-transferases%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273923%22%3E%3Ci%3EDDB_G0273923%3C%2Fi%3E%3C%2Fa%3E
chr2	2472439	2473672	-	DDB_G0273155	DDB_G0273155	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273921%22%3E%3Ci%3EDDB_G0273921%3C%2Fi%3E%3C%2Fa%3E
chr2	2474613	2475374	-	DDB_G0273063	dscA-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273919%22%3E%3Ci%3EdscA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2476242	2477994	-	DDB_G0273321	DDB_G0273321	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273917%22%3EDDB_G0273917%3C%2Fa%3E
chr2	2479032	2480045	+	DDB_G0273157	iliE-1	induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273915%22%3E%3Ci%3EiliE-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2480367	2480582	+	DDB_G0273159	DDB_G0273159	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273913%22%3EDDB_G0273913%3C%2Fa%3E
chr2	2481710	2482439	+	DDB_G0273161	DDB_G0273161	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273911%22%3EDDB_G0273911%3C%2Fa%3E
chr2	2482779	2484020	+	DDB_G0273163	psmB4-1	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273909%22%3E%3Ci%3EpsmB4-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2484199	2485276	-	DDB_G0273165	DDB_G0273165	catalyses the endonucleolytic cleavage of apurinic or apyrimidinic sites to generate products with a 5%27-phosphate%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3D DDB_G0273907%22%3E%3Ci%3E DDB_G0273907%3C%2Fi%3E%3C%2Fa%3E
chr2	2485605	2486048	-	DDB_G0273167	DDB_G0273167	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273905%22%3EDDB_G0273905%3C%2Fa%3E
chr2	2486835	2491344	+	DDB_G0273171	irlF-1	putative protein serine%2Fthreonine kinase%3B the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273903%22%3E%3Ci%3EirlF-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2492015	2492088	+	DDB_G0294835	tRNA-Phe-GAA-3	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294987%22%3E%3Ci%3EtRNA-Phe-GAA-8%3C%2Fi%3E%3C%2Fa%3E 
chr2	2492298	2495234	-	DDB_G0273263	DDB_G0273263_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273901%22%3E%3Ci%3EDDB_G0273901_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2495550	2495882	-	DDB_G0273265	DDB_G0273265	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273899%22%3EDDB_G0273899%3C%2Fa%3E
chr2	2497136	2498000	-	DDB_G0273323	DDB_G0273323_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273897%22%3E%3Ci%3EDDB_G0273897_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2498149	2498220	+	DDB_G0294837	tRNA-Glu-UUC-7	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294989%22%3E%3Ci%3EtRNA-Glu-UUC-10%3C%2Fi%3E%3C%2Fa%3E 
chr2	2498827	2500566	+	DDB_G0273169	DDB_G0273169	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273895%22%3EDDB_G0273895%3C%2Fa%3E
chr2	2502953	2505253	+	DDB_G0273173	DDB_G0273173	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273893%22%3EDDB_G0273893%3C%2Fa%3E
chr2	2506006	2506155	-	DDB_G0348645	dsc_ps1	putative pseudogene%3B short fragment%3B similar to D. discoideum discoidin gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0273065%22%3E%3Ci%3EdscC-1%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0273067%22%3E%3Ci%3EdscD-1%3C%2Fi%3E%3C%2Fa%3E%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0348648%22%3E%3Ci%3Edsc_ps2%3C%2Fi%3E%3C%2Fa%3E
chr2	2506873	2506951	-	DDB_G0294999	tRNA-Leu-UAG-2	transfers a leucine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294847%22%3E%3Ci%3EtRNA-Leu-UAG-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	2508437	2508899	-	DDB_G0273269	DDB_G0273269_ps	putative pseudogene%3B fragment%2C similar to UNC93-like protein MFSD11 family members %3Ca href%3D%22%2Fgene%2FDDB_G0291720%22%3EDDB_G0291720%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0291722%22%3EDDB_G0291722%3C%2Fa%3E%3B%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273889%22%3EDDB_G0273889%3C%2Fa%3E
chr2	2509980	2510741	-	DDB_G0273067	dscD-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273887%22%3E%3Ci%3EdscD-2%3C%2Fi%3E%3C%2Fa%3E  
chr2	2511465	2512226	-	DDB_G0273065	dscC-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273885%22%3E%3Ci%3EdscC-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2513207	2513278	-	DDB_G0294997	tRNA-Met-CAU-11	transfers a methionine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294845%22%3E%3Ci%3EtRNA-Met-CAU-6%3C%2Fi%3E%3C%2Fa%3E 
chr2	2514908	2516741	+	DDB_G0273271	DDB_G0273271_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273883%22%3E%3Ci%3EDDB_G0273883_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2516614	2516685	+	DDB_G0294839	tRNA-Met-CAU-5	transfers a methionine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294991%22%3E%3Ci%3EtRNA-Met-CAU-10%3C%2Fi%3E%3C%2Fa%3E 
chr2	2517024	2517905	+	DDB_G0273325	DDB_G0273325_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273881%22%3E%3Ci%3EDDB_G0273881_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2518055	2520640	+	DDB_G0273327	DDB_G0273327_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273879%22%3E%3Ci%3EDDB_G0273879_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2520747	2521350	+	DDB_G0273329	DDB_G0273329_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273877%22%3E%3Ci%3EDDB_G0273877_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2522303	2523214	+	DDB_G0273175	cf50-1	component of the counting factor complex%2C which includes CF60%2C CF50%2C CF45-1%2C and CtnA (countin)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273875%22%3E%3Ci%3Ecf50-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2523859	2526131	-	DDB_G0273151	DDB_G0273151	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273873%22%3EDDB_G0273873%3C%2Fa%3E
chr2	2526700	2527317	-	DDB_G0273177	DDB_G0273177	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273871%22%3EDDB_G0273871%3C%2Fa%3E
chr2	2528420	2530624	-	DDB_G0273125	DDB_G0273125	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273869%22%3EDDB_G0273869%3C%2Fa%3E 
chr2	2531335	2532417	+	DDB_G0273123	DDB_G0273123	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273867%22%3EDDB_G0273867%3C%2Fa%3E 
chr2	2532742	2534490	+	DDB_G0273121	pakH-1	putative protein serine%2Fthreonine kinase%3B similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B belongs to the PAKL subfamily%3B stress-responsive kinase%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?dictybaseid%3DDDB0266965%22%3EpakH-2 %3C%2Fa%3E
chr2	2535890	2536332	-	DDB_G0273119	DDB_G0273119	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273863%22%3EDDB_G0273863%3C%2Fa%3E
chr2	2537016	2538312	+	DDB_G0273117	ublcp1-1	ortholog of the H. sapiens UBLCP1%2C a conserved protein that contains a ubiquitin and a NLI interacting factor domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273861%22%3E%3Ci%3Eublcp1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2538856	2539512	+	DDB_G0273331	DDB_G0273331	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273859%22%3EDDB_G0273859%3C%2Fa%3E
chr2	2539802	2544227	-	DDB_G0273333	irlB-1	putative protein serine%2Fthreonine kinase%3B the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273857%22%3E%3Ci%3EirlB-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2544712	2545626	-	DDB_G0295833	DDB_G0295833	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273855%22%3E%3Ci%3EDDB_G0273855%3C%2Fi%3E%3C%2Fa%3E
chr2	2545999	2546529	+	DDB_G0273115	DDB_G0273115	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273853%22%3E%3Ci%3E DDB_G0273853%3C%2Fi%3E%3C%2Fa%3E
chr2	2546637	2547389	-	DDB_G0273113	DDB_G0273113	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273851%22%3EDDB_G0273851%3C%2Fa%3E
chr2	2548178	2548387	-	DDB_G0273111	DDB_G0273111	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273849%22%3EDDB_G0273849%3C%2Fa%3E
chr2	2549398	2549601	-	DDB_G0273337	DDB_G0273337_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0273799%22%3EDDB_G0273799%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273845%22%3EDDB_G0273845_ps%3C%2Fa%3E
chr2	2550408	2550986	-	DDB_G0273273	DDB_G0273273	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273843%22%3E%3Ci%3E DDB_G0273843%3C%2Fi%3E%3C%2Fa%3E
chr2	2552049	2553225	-	DDB_G0273109	DDB_G0273109	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273841%22%3EDDB_G0273841%3C%2Fa%3E
chr2	2554330	2560780	+	DDB_G0273107	fip-1	interacts with filamin (abpC) and plays a role in development and phototaxis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273839%22%3E%3Ci%3Efip-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2562086	2564867	+	DDB_G0273105	scdB-1	contains a cytochrome b5 domain%3B introduces a double bond at the delta position of fatty acids during the biosynthesis of monounsaturated fatty acids%3B there is a second copy of this gene %3Ca href%3D%22%2Fgene%2FDDB_G0273837%22%3E%3Ci%3EscdB-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2565766	2566560	+	DDB_G0273103	DDB_G0273103	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273835%22%3EDDB_G0273835%3C%2Fa%3E
chr2	2566700	2568175	-	DDB_G0273275	DDB_G0273275	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273833%22%3EDDB_G0273833%3C%2Fa%3E
chr2	2569065	2575617	+	DDB_G0273101	DDB_G0273101	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273831%22%3E%3Ci%3EDDB_G0273831%3C%2Fi%3E%3C%2Fa%3E
chr2	2575884	2577531	-	DDB_G0273277	DDB_G0273277	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273829%22%3EDDB_G0273829%3C%2Fa%3E
chr2	2578304	2579413	+	DDB_G0273279	DDB_G0273279	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273827%22%3EDDB_G0273827%3C%2Fa%3E
chr2	2580465	2581232	+	DDB_G0273099	rsmE-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273825%22%3E%3Ci%3ErsmE-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2581380	2582813	-	DDB_G0273281	DDB_G0273281	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273823%22%3EDDB_G0273823%3C%2Fa%3E
chr2	2583982	2584549	+	DDB_G0273283	DDB_G0273283	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273821%22%3EDDB_G0273821%3C%2Fa%3E
chr2	2584694	2586199	-	DDB_G0273179	DDB_G0273179	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273819%22%3EDDB_G0273819%3C%2Fa%3E
chr2	2586710	2588480	-	DDB_G0273097	ptpA1-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273817%22%3E%3Ci%3EptpA1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2590732	2591358	+	DDB_G0273095	DDB_G0273095	similar to human PDAP1 (PDGFA-associated protein 1)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273815%22%3E %3Ci%3EDDB_G0273815%3C%2Fi%3E%3C%2Fa%3E
chr2	2591482	2594701	-	DDB_G0273093	DDB_G0273093	similar to the mammalian Hypoxia up-regulated protein 1 (HYOU1)%2C a protein that plays a role in cytoprotective cellular mechanisms triggered by oxygen deprivation%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273813%22%3E%3Ci%3EDDB_G0273813%3C%2Fi%3E%3C%2Fa%3E
chr2	2595096	2598634	-	DDB_G0273339	DDB_G0273339	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273811%22%3EDDB_G0273811%3C%2Fa%3E
chr2	2599717	2600930	+	DDB_G0273091	DDB_G0273091	member of the ZIP (Zrt- and Irt-like Protein) family capable of transporting zinc and other metal ions%3B contains 6 transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273809%22%3E%3Ci%3EDDB_G0273809%3C%2Fi%3E%3C%2Fa%3E
chr2	2602576	2602843	+	DDB_G0273181	DDB_G0273181	contains no functional domains and is not similar to any other protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273807%22%3E%3Ci%3EDDB_G0273807%3C%2Fi%3E%3C%2Fa%3E
chr2	2603092	2603825	-	DDB_G0273069	ndkC-1	catalyzes the phosphorylation of nucleoside or deoxynucleoside diphosphates into the corresponding triphosphates%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273805%22%3E%3Ci%3EndkC-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2604150	2604852	-	DDB_G0273089	coq10-1	ortholog of the conserved COQ10%2C a Coenzyme Q (ubiquinone) binding protein in %3Ci%3ES. cerevisiae%3C%2Fi%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273803%22%3E%3Ci%3Ecoq10-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2605221	2610959	-	DDB_G0273087	DDB_G0273087_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0290841%22%3EDDB_G0290841%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0287167%22%3EDDB_G0287167%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273801%22%3E%3Ci%3EDDB_G0273801%3C%2Fi%3E%3C%2Fa%3E
chr2	2612260	2612484	+	DDB_G0273183	DDB_G0273183	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273799%22%3EDDB_G0273799%3C%2Fa%3E
chr2	2612891	2613072	+	DDB_G0273341	DDB_G0273341	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273797%22%3EDDB_G0273797%3C%2Fa%3E
chr2	2613529	2620949	-	DDB_G0273285	DDB_G0273285	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273795%22%3E%3Ci%3E DDB_G0273795%3C%2Fi%3E%3C%2Fa%3E
chr2	2621919	2623505	+	DDB_G0273085	DDB_G0273085	contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273791%22%3EDDB_G0273791%3C%2Fa%3E
chr2	2623576	2624496	-	DDB_G0273083	DDB_G0273083	member of the Dyp-type peroxidase family lacking a typical heme-binding region%3B does not appear to be present in higher organisms%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273789%22%3E%3Ci%3EDDB_G0273789%3C%2Fi%3E%3C%2Fa%3E
chr2	2625067	2626656	+	DDB_G0273081	DDB_G0273081	similar to histidine ammonia-lyase%2C which catalyzes the reaction L-histidine %3D urocanate %2B NH%3Csub%3E3%3C%2Fsub%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273787%22%3E%3Ci%3EDDB_G0273787%3C%2Fi%3E%3C%2Fa%3E
chr2	2626943	2627719	-	DDB_G0273289	DDB_G0273289	no homologs in other organisms%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273785%22%3E%3Ci%3EDDB_G0273785%3C%2Fi%3E%3C%2Fa%3E 
chr2	2628315	2629355	-	DDB_G0273291	ddo-2	catalyzes the oxidation of neutral and basic D-amino acids into their corresponding keto acids%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273783%22%3E%3Ci%3Eddo-1%3C%2Fi%3E%3C%2Fa%3E
chr2	2630264	2634881	-	DDB_G0273073	abcG17-1	full transporter%2C consisting of two ABC domains and two transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273073%22%3E%3Ci%3EabcG17-1%3C%2Fi%3E%3C%2Fa%3E
chr2	2636071	2637483	-	DDB_G0273293	DDB_G0273293	NA
chr2	2638627	2639784	-	DDB_G0273343	DDB_G0273343	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273777%22%3EDDB_G0273777%3C%2Fa%3E 
chr2	2640075	2640943	+	DDB_G0273061	cinD-1	ortholog of Saccharomyces cerevisiae Mbf1 protein%3B expressed at high level in vegetative celly and decreases sharply in early development%3B induced by cycloheximide%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273775%22%3E%3Ci%3EcinD-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2641934	2642410	+	DDB_G0273079	DDB_G0273079	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273773%22%3E%3Ci%3EDDB_G0273773%3C%2Fi%3E%3C%2Fa%3E
chr2	2642763	2643257	-	DDB_G0273295	DDB_G0273295	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273771%22%3EDDB_G0273771%3C%2Fa%3E
chr2	2643893	2644517	+	DDB_G0273297	DDB_G0273297	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273769%22%3EDDB_G0273769%3C%2Fa%3E 
chr2	2646033	2647664	+	DDB_G0273077	DDB_G0273077	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273767%22%3EDDB_G0273767%3C%2Fa%3E
chr2	2647848	2651990	-	DDB_G0273075	DDB_G0273075	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273765%22%3E%3Ci%3EDDB_G0273765%3C%2Fi%3E%3C%2Fa%3E
chr2	2652628	2654045	+	DDB_G0273299	DDB_G0273299	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273763%22%3EDDB_G0273763%3C%2Fa%3E
chr2	2655025	2658168	-	DDB_G0273345	DDB_G0273345_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273761%22%3E%3Ci%3EDDB_G0273761_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2658459	2659793	-	DDB_G0273347	DDB_G0273347_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273759%22%3E%3Ci%3EDDB_G0273759_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	2661584	2661666	+	DDB_G0294841	tRNA-Leu-UAA-1	transfers a leucine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294993%22%3E%3Ci%3EtRNA-Leu-UAA-6%3C%2Fi%3E%3C%2Fa%3E 
chr2	2661937	2662708	-	DDB_G0273349	cyp518A2_ps-1	putative pseudogene%3B related to the cytochrome P450 family%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273757%22%3E%3Ci%3Ecyp518A2_ps-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2662753	2662824	+	DDB_G0294843	tRNA-Thr-AGU-13	transfers a threonine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294995%22%3E%3Ci%3EtRNA-Thr-AGU-15%3C%2Fi%3E%3C%2Fa%3E  
chr2	2663113	2668443	-	DDB_G0273351	DDB_G0273351	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273755%22%3EDDB_G0273755%3C%2Fa%3E
chr2	2668726	2671271	-	DDB_G0273301	DDB_G0273301	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273753%22%3EDDB_G0273753%3C%2Fa%3E
chr2	2671646	2673138	+	DDB_G0273353	fnkG_ps-1	putative pseudogene%3B STE%2FFNIP protein kinase family%3B %09there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273751%22%3E%3Ci%3EfnkG_ps-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2673521	2677171	+	DDB_G0273185	DDB_G0273185	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273749%22%3EDDB_G0273749%3C%2Fa%3E
chr2	2677894	2678085	+	DDB_G0273187	DDB_G0273187	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273747%22%3EDDB_G0273747%3C%2Fa%3E
chr2	2679135	2681639	+	DDB_G0273189	DDB_G0273189	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273745%22%3E%3Ci%3EDDB_G0273745%3C%2Fi%3E%3C%2Fa%3E
chr2	2681849	2682650	-	DDB_G0273191	rps30-1	protein component of the small (40S) ribosomal subunit%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273743%22%3E%3Ci%3Erps30-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2683400	2684488	+	DDB_G0273355	rexo2-1	similar to H. sapiens REXO2 and S. cerevisiae REX2%2C a mitochondrial 3%27-5%27 RNA exonuclease%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273741%22%3E%3Ci%3Erexo2-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2684717	2686674	-	DDB_G0273193	DDB_G0273193	shares a short region of similarity with the human gene TEX2 (expressed in testis)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273739%22%3E%3Ci%3EDDB_G0273739%3C%2Fi%3E%3C%2Fa%3E
chr2	2688821	2690431	+	DDB_G0273059	cak1-1	protein serine%2Fthreonine kinase%2C CK1 family%3B similar to human CK1 and yeast YCK%3B may play a role in DNA repair%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273737%22%3E%3Ci%3Ecak1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2690707	2692470	-	DDB_G0273195	DDB_G0273195	member of the major facilitator superfamily (MFS)%3B expressed in upper cup during culmination%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273735%22%3E%3Ci%3EDDB_G0273735%3C%2Fi%3E%3C%2Fa%3E
chr2	2693104	2695175	-	DDB_G0273357	DDB_G0273357	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273733%22%3E%3Ci%3EDDB_G0273733%3C%2Fi%3E%3C%2Fa%3E
chr2	2696096	2697063	-	DDB_G0273197	alyD-1	member of a new lysozyme class
chr2	2698234	2699664	+	DDB_G0273199	mkpB-1	putative protein tyrosine phosphatase%3B similar to the cofilin phosphatase slingshot and to other dual-specificity phosphatases%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273729%22%3E%3Ci%3EmkpB-2%3C%2Fi%3E%3C%2Fa%3E%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E The single Dicty homologue of the cofilin phosphatase slingshot. %3Ci%3ERobert Insall July 2007%3C%2Fi%3E
chr2	2699843	2700652	+	DDB_G0273201	DDB_G0273201	similar to MAD2 and REV7%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273727%22%3E%3Ci%3EDDB_G0273727%3C%2Fi%3E%3C%2Fa%3E
chr2	2700893	2702467	-	DDB_G0273203	snf12-1	nuclear protein and ortholog of yeast SNF12 and human SMARCD1 that are involved in chromatin remodeling%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273725%22%3E%3Ci%3Esnf12-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2704086	2707118	+	DDB_G0273205	DDB_G0273205	contains an EF hand but shows little similarity to other proteins%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273723%22%3E%3Ci%3EDDB_G0273723%3C%2Fi%3E%3C%2Fa%3E
chr2	2708039	2710364	+	DDB_G0273207	cdk9-1	similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273721%22%3E%3Ci%3Ecdk9-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2711050	2715761	+	DDB_G0273209	trappc10-1	ortholog of the trafficking protein particle complex subunit 10%2C part of the multisubunit TRAPP (transport protein particle) complex%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273719%22%3E%3Ci%3Etrappc10-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2715892	2717923	-	DDB_G0273211	aslD-1	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273717%22%3E%3Ci%3EaslD-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2718060	2718470	-	DDB_G0273303	aslE_ps-1	putative pseudogene%3B AMP-dependent synthetase and ligase family protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273715%22%3E%3Ci%3EaslE_ps-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2719022	2721057	-	DDB_G0273213	aslA-1	highly similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B expressed in pstAB cells and in upper and lower cups during culmination%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273713%22%3E%3Ci%3EaslA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2722019	2724024	-	DDB_G0273359	aslG_ps-1	putative pseudogene%3B AMP-dependent synthetase and ligase family protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273711%22%3E%3Ci%3EaslG_ps-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2725007	2727011	-	DDB_G0273215	aslG-1	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273709%22%3E%3Ci%3EaslG-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2727455	2728390	-	DDB_G0273361	DDB_G0273361	contains 5 transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273707%22%3E%3Ci%3EDDB_G0273707%3C%2Fi%3E%3C%2Fa%3E
chr2	2728893	2729486	-	DDB_G0273217	DDB_G0273217	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273705%22%3EDDB_G0273705%3C%2Fa%3E
chr2	2729906	2731354	-	DDB_G0273219	DDB_G0273219	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273703%22%3EDDB_G0273703%3C%2Fa%3E
chr2	2732471	2733230	+	DDB_G0273221	DDB_G0273221	conserved protein of unknown function%3B contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273701%22%3E%3Ci%3EDDB_G0273701%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr2	2733819	2736050	+	DDB_G0273223	aslO-1	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273699%22%3E%3Ci%3EaslO-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2736552	2738602	+	DDB_G0273225	aslC-1	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273697%22%3E%3Ci%3EaslC-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2738884	2740904	+	DDB_G0273227	aslI-1	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273695%22%3E%3Ci%3EaslI-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2741497	2743033	+	DDB_G0273363	aslI_ps-1	putative pseudogene%3B acetyl-CoA synthetase family protein%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273693%22%3E%3Ci%3EaslI_ps-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2743505	2745522	+	DDB_G0273305	aslJ-1	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273691%22%3E%3Ci%3EaslJ-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2746225	2748240	+	DDB_G0273229	aslK-1	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273689%22%3E%3Ci%3EaslK-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2750963	2752978	+	DDB_G0273365	aslL-1	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273687%22%3E%3Ci%3EaslL-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2754939	2755304	+	DDB_G0273367	DDB_G0273367	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273685%22%3EDDB_G0273685%3C%2Fa%3E
chr2	2756320	2760155	+	DDB_G0273371	DDB_G0273371	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273681%22%3EDDB_G0273681%3C%2Fa%3E
chr2	2760431	2763018	-	DDB_G0273231	DDB_G0273231	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273679%22%3EDDB_G0273679%3C%2Fa%3E
chr2	2763989	2765107	-	DDB_G0273233	DDB_G0273233	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273677%22%3EDDB_G0273677%3C%2Fa%3E
chr2	2765356	2769268	-	DDB_G0273235	DDB_G0273235	contains 8 transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273675%22%3E%3Ci%3EDDB_G0273675%3C%2Fi%3E%3C%2Fa%3E
chr2	2770909	2772066	+	DDB_G0273237	DDB_G0273237	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273673%22%3E%3Ci%3EDDB_G0273673%3C%2Fi%3E%3C%2Fa%3E
chr2	2772386	2773399	-	DDB_G0273307	DDB_G0273307_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0282843%22%3EDDB_G0282843%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0282839%22%3EDDB_G0282839%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273671%22%3EDDB_G0273671_ps%3C%2Fa%3E 
chr2	2775403	2779257	+	DDB_G0273257	comF-1	REMI mutant fails to aggregate%3B contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273669%22%3E%3Ci%3EcomF-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2781320	2781776	+	DDB_G0273373	DDB_G0273373	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273667%22%3EDDB_G0273667%3C%2Fa%3E
chr2	2783058	2784333	+	DDB_G0273375	DDB_G0273375_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273663%22%3EDDB_G0273663%3C%2Fa%3E
chr2	2784903	2785097	+	DDB_G0273241	DDB_G0273241	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273661%22%3EDDB_G0273661%3C%2Fa%3E
chr2	2785722	2785892	+	DDB_G0273243	DDB_G0273243	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273659%22%3EDDB_G0273659%3C%2Fa%3E
chr2	2787988	2789460	+	DDB_G0273071	vatD-1	ortholog of the D subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the D subunit is part of the V1 subunit%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273657%22%3E%3Ci%3EvatD-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2789660	2791008	-	DDB_G0273377	DDB_G0273377	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273655%22%3EDDB_G0273655%3C%2Fa%3E
chr2	2791662	2794439	+	DDB_G0273245	DDB_G0273245	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273653%22%3EDDB_G0273653%3C%2Fa%3E 
chr2	2794534	2799419	-	DDB_G0273247	DDB_G0273247	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273651%22%3EDDB_G0273651%3C%2Fa%3E
chr2	2802060	2805727	+	DDB_G0273379	DDB_G0273379	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273647%22%3EDDB_G0273647%3C%2Fa%3E
chr2	2807924	2813408	+	DDB_G0273127	hbx5-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273645%22%3E%3Ci%3Ehbx5-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2813973	2818645	+	DDB_G0273381	DDB_G0273381	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273643%22%3EDDB_G0273643%3C%2Fa%3E
chr2	2818823	2821201	-	DDB_G0273129	fnkD-1	contains six Dictyostelium-specific FNIP repeats%3B unlikely to function as a kinase as it does not contain a catalytic aspartate%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273641%22%3E%3Ci%3EfnkD-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2821995	2823882	-	DDB_G0273131	g6pd-1	ortholog of the human G6PD%3B defects in G6PD cause chronic non-spherocytic hemolytic anemia (CNSHA)%3B catalyzes the reaction D-glucose 6-phosphate %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %3D D-glucono-1%2C5-lactone 6-phosphate %2B NADPH %2B H%3Csup%3E%2B%3C%2Fsup%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273639%22%3E%3Ci%3Eg6pd-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2829694	2830426	+	DDB_G0273311	DDB_G0273311	contains no functional domains%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273637%22%3E%3Ci%3EDDB_G0273637%3C%2Fi%3E%3C%2Fa%3E
chr2	2831844	2836595	+	DDB_G0273259	qkgA-1	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains LRR%2C Roc%2C COR%2C and protein kinase domains%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273635%22%3E%3Ci%3EqkgA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2836914	2839604	+	DDB_G0273133	DDB_G0273133	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273633%22%3EDDB_G0273633%3C%2Fa%3E
chr2	2839698	2840585	-	DDB_G0273383	cwc15-1	ortholog of S. pombe Cwf15 and S. cerevisiae Cwc15%2C thought to be non-essential components of an mRNA splicing complex%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273631%22%3E%3Ci%3Ecwc15-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2840909	2844367	-	DDB_G0273385	DDB_G0273385	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273629%22%3EDDB_G0273629%3C%2Fa%3E
chr2	2845293	2846047	-	DDB_G0273313	DDB_G0273313	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273627%22%3EDDB_G0273627%3C%2Fa%3E
chr2	2846671	2847700	+	DDB_G0273135	DDB_G0273135	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273625%22%3EDDB_G0273625%3C%2Fa%3E
chr2	2848730	2850628	-	DDB_G0273249	hspE-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273623%22%3E%3Ci%3EhspE-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2851916	2853363	+	DDB_G0273315	DDB_G0273315	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273621%22%3EDDB_G0273621%3C%2Fa%3E
chr2	2854787	2856847	+	DDB_G0273137	DDB_G0273137	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273617%22%3EDDB_G0273617%3C%2Fa%3E
chr2	2857157	2857799	-	DDB_G0273251	fpaB-1	component of the SCF ubiquitin ligase complex%3B the fpaB gene encodes a protein almost identical to that of fpaA%2C differing in one amino acid only%3B series of glycosylation reactions attaches a pentasaccharide chain to HyPro143%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273615%22%3E%3Ci%3EfpaB-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2859896	2860720	+	DDB_G0273387	DDB_G0273387	expressed in pstAO cells and in upper cup during culmination%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273613%22%3E%3Ci%3EDDB_G0273613%3C%2Fi%3E%3C%2Fa%3E
chr2	2861364	2862597	-	DDB_G0273139	rad51-1	ortholog of Rad51%2C which is involved in activation of homologous recombination and double-strand break repair and interacts with XRCC3%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273611%22%3E%3Ci%3Erad51-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2863138	2865135	-	DDB_G0273141	cblA-1	homolog of the metazoan cbl proteins%3B contains a tyrosine kinase binding domain (TBK) at the amino terminus connected to a RING finger%3B regulates STAT signaling via PTP3%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273609%22%3E%3Ci%3EcblA-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2866004	2866525	-	DDB_G0273143	DDB_G0273143	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273607%22%3EDDB_G0273607%3C%2Fa%3E
chr2	2866812	2869069	-	DDB_G0273389	psiG-1	contains a PA14 (anthrax protection antigen) domain and 6 Dictyostelium (CTDC) repeats%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273605%22%3E%3Ci%3EpsiG-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	2870213	2870485	-	DDB_G0273319	DDB_G0273319	NA
chr2	2871173	2872411	-	DDB_G0273261	sigL-1	regulated by the MADS-box transcription factor SrfA during development%3B expressed in stalk cells%3B contains one EGF domain and a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273601%22%3E%3Ci%3EsigL-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2872889	2873953	-	DDB_G0273145	DDB_G0273145	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273599%22%3EDDB_G0273599%3C%2Fa%3E
chr2	2874426	2875405	-	DDB_G0273147	DDB_G0273147	has similarity to the %3C%2Fi%3ES. cerevisisae%3C%2Fi%3E ATP10%2C a mitochondrial inner membrane protein required for assembly of the mitochondrial F1F0 ATP synthase%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273597%22%3E%3Ci%3EDDB_G0273597%3C%2Fi%3E%3C%2Fa%3E
chr2	2875789	2877605	-	DDB_G0273149	DDB_G0273149	functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC)%3B contains a N-terminal importin beta binding domain (IBB domain)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273595%22%3E%3Ci%3EDDB_G0273595%3C%2Fi%3E%3C%2Fa%3E
chr2	2879174	2881647	-	DDB_G0273391	DDB_G0273391	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273593%22%3E%3Ci%3E DDB_G0273593%3C%2Fi%3E%3C%2Fa%3E
chr2	2883211	2884452	+	DDB_G0273393	DDB_G0273393	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273591%22%3E%3Ci%3EDDB_G0273591%3C%2Fi%3E%3C%2Fa%3E
chr2	2884698	2885858	+	DDB_G0273253	DDB_G0273253	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273589%22%3E%3Ci%3EDDB_G0273589%3C%2Fi%3E%3C%2Fa%3E
chr2	2886386	2886532	-	DDB_G0273395	DDB_G0273395	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273587%22%3EDDB_G0273587%3C%2Fa%3E
chr2	2887233	2887424	-	DDB_G0273255	DDB_G0273255	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273585%22%3EDDB_G0273585%3C%2Fa%3E
chr2	2890795	2891352	+	DDB_G0273467	trappc1-1	conserved trafficking protein particle (TRAPP) complex subunit%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273579%22%3Etrappc1-2%3C%2Fa%3E
chr2	2891795	2893160	-	DDB_G0273449	DDB_G0273449	part of a small Dictyostelium protein family%3B enriched in gametes%3B contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273577%22%3E%3Ci%3EDDB_G0273577%3C%2Fi%3E%3C%2Fa%3E
chr2	2893976	2894131	+	DDB_G0273403	DDB_G0273403	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273575%22%3EDDB_G0273575%3C%2Fa%3E
chr2	2894718	2911917	-	DDB_G0273451	DDB_G0273451	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273573%22%3E%3Ci%3EDDB_G0273573%3C%2Fi%3E%3C%2Fa%3E
chr2	2913032	2914005	+	DDB_G0273405	DDB_G0273405_ps	putative pseudogene%3B similar to coactosin%2C contains an ADF (actin depolymerisation factor%2Fcofilin-like) domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273569%22%3E%3Ci%3EDDB_G0273569_ps%3C%2Fi%3E%3C%2Fa%3E
chr2	2914216	2917110	-	DDB_G0273453	DDB_G0273453	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273565%22%3E%3Ci%3EDDB_G0273565%3C%2Fi%3E%3C%2Fa%3E
chr2	2917844	2920307	+	DDB_G0273471	dpp3-1	catalyzes the release of an N-terminal dipeptide from a peptide comprising four or more residues%2C with broad specificity%3B highly selective for Arg-Arg-2-naphthylamide%2C at pH 9.2%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273563%22%3E%3Ci%3Edpp3-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2921093	2921794	-	DDB_G0273409	hspF-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273561%22%3E%3Ci%3EhspF-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2922562	2926126	-	DDB_G0273473	DDB_G0273473	conserved hypothetical protein%3B similar to esophageal cancer associated protein%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273559%22%3E%3Ci%3EDDB_G0273559%3C%2Fi%3E%3C%2Fa%3E
chr2	2926565	2931880	-	DDB_G0273475	dhkI-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0295835%22%3E%3Ci%3EdhkI-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2933551	2935380	-	DDB_G0273477	DDB_G0273477	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273557%22%3EDDB_G0273557%3C%2Fa%3E
chr2	2935949	2936770	+	DDB_G0273411	DDB_G0273411	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273555%22%3EDDB_G0273555%3C%2Fa%3E 
chr2	2936962	2939655	-	DDB_G0273443	atg4-1	ortholog of the conserved ATG4 cysteine protease involved in autophagy%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3D %09DDB_G0273553%22%3E%3Ci%3Eatg4-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2940321	2941691	+	DDB_G0273413	DDB_G0273413	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273551%22%3E%3Ci%3EDDB_G0273551%3C%2Fi%3E%3C%2Fa%3E
chr2	2941844	2942917	-	DDB_G0273415	DDB_G0273415	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273549%22%3EDDB_G0273549%3C%2Fa%3E
chr2	2943449	2945021	+	DDB_G0273417	DDB_G0273417	similar to bacterial S-adenosyl-L-methionine (SAM) methyltransferases%3B similar to D. purpureum protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273547%22%3E%3Ci%3EDDB_G0273547%3C%2Fi%3E%3C%2Fa%3E
chr2	2945279	2947444	-	DDB_G0273479	nfyC-1	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273545%22%3E%3Ci%3EnfyC-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2951458	2953693	+	DDB_G0273481	DDB_G0273481	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273543%22%3E%3Ci%3E DDB_G0273543%3C%2Fi%3E%3C%2Fa%3E
chr2	2955221	2959208	+	DDB_G0273419	DDB_G0273419	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273539%22%3EDDB_G0273539%3C%2Fa%3E
chr2	2959446	2961113	-	DDB_G0273483	DDB_G0273483	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273537%22%3EDDB_G0273537%3C%2Fa%3E 
chr2	2961762	2963492	-	DDB_G0273399	mip1-1	physically interacts with and ubiquinates the MAP kinase kinase Mek1 (mekA) and controls its nuclear localization%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273535%22%3E%3Ci%3Emip1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2964374	2965695	-	DDB_G0273397	carA-1	high affinity cAMP receptor%3B belongs to the serpentine%2FG-protein coupled receptor family%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273533%22%3E%3Ci%3EcarA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2969377	2971620	-	DDB_G0273445	spkA-1	member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family%3B kinase activity stimulated by hyperosmolarity and heat shock%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273531%22%3E%3Ci%3EspkA-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2972872	2975587	+	DDB_G0273421	DDB_G0273421	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273529%22%3EDDB_G0273529%3C%2Fa%3E
chr2	2975860	2977092	-	DDB_G0273423	DDB_G0273423	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273527%22%3EDDB_G0273527%3C%2Fa%3E
chr2	2978253	2980341	+	DDB_G0273525	gtf2e1-1	TFIIE large subunit%2C involved in recruitment of RNA polymerase II to the promoter%2C activation of TFIIH%2C and promoter opening%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273583%22%3E%3Ci%3Egtf2e1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2980579	2981451	-	DDB_G0273425	rpc25-1	component of the RNA polymerase III complex%3B ortholog of S. cerevisiae RPC25 and H. sapiens RPC8%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273523%22%3E%3Ci%3Erpc25-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2982372	2982819	-	DDB_G0273427	DDB_G0273427	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273521%22%3EDDB_G0273521%3C%2Fa%3E
chr2	2982881	2983756	-	DDB_G0273457	nit1-1	similar to mammalian NIT1%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273519%22%3E%3Ci%3Enit1-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2984113	2985640	-	DDB_G0273447	abpE-1	involved in pseudopod formation%3B contains an N-terminal ADF%2Fcofilin-like actin binding domain and a c-terminal SH3 domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273517%22%3E%3Ci%3EabpE-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2986448	2987269	+	DDB_G0273459	DDB_G0273459	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273515%22%3EDDB_G0273515%3C%2Fa%3E
chr2	2988290	2989955	+	DDB_G0273429	hpdl-1	catalyzes the reaction 4-hydroxyphenylpyruvate %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E homogentisate %2B CO%3Csub%3E2%3C%2Fsub%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273513%22%3E%3Ci%3Ehpdl-2%3C%2Fi%3E%3C%2Fa%3E
chr2	2990349	2991404	+	DDB_G0273431	DDB_G0273431	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273511%22%3EDDB_G0273511%3C%2Fa%3E
chr2	2992272	2993729	+	DDB_G0273433	DDB_G0273433	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273509%22%3EDDB_G0273509%3C%2Fa%3E
chr2	2997078	2998385	-	DDB_G0273435	DDB_G0273435	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273505%22%3EDDB_G0273505%3C%2Fa%3E
chr2	2999157	3000505	-	DDB_G0273437	DDB_G0273437	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273503%22%3EDDB_G0273503%3C%2Fa%3E
chr2	3000942	3004624	-	DDB_G0273439	ap2a1-1	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273501%22%3E%3Ci%3Eap2a1-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	3006071	3007438	-	DDB_G0273463	DDB_G0273463	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273499%22%3EDDB_G0273499%3C%2Fa%3E
chr2	3008502	3011008	+	DDB_G0273441	DDB_G0273441	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273497%22%3EDDB_G0273497%3C%2Fa%3E 
chr2	3011236	3012206	-	DDB_G0273465	DDB_G0273465	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273495%22%3EDDB_G0273495%3C%2Fa%3E 
chr2	3012756	3013754	+	DDB_G0273485	DDB_G0273485	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273493%22%3EDDB_G0273493%3C%2Fa%3E 
chr2	3014131	3014933	-	DDB_G0273487	DDB_G0273487	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273491%22%3EDDB_G0273491%3C%2Fa%3E
chr2	3016853	3017655	+	DDB_G0273491	DDB_G0273491	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273487%22%3EDDB_G0273487%3C%2Fa%3E
chr2	3018032	3019030	-	DDB_G0273493	DDB_G0273493	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273485%22%3EDDB_G0273485%3C%2Fa%3E 
chr2	3019580	3020550	+	DDB_G0273495	DDB_G0273495	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273465%22%3EDDB_G0273465%3C%2Fa%3E 
chr2	3020778	3023284	-	DDB_G0273497	DDB_G0273497	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273441%22%3EDDB_G0273441%3C%2Fa%3E 
chr2	3024348	3025715	+	DDB_G0273499	DDB_G0273499	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273463%22%3EDDB_G0273463%3C%2Fa%3E
chr2	3027162	3030844	+	DDB_G0273501	ap2a1-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273439%22%3E%3Ci%3Eap2a1-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3031281	3032629	+	DDB_G0273503	DDB_G0273503	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273437%22%3EDDB_G0273437%3C%2Fa%3E
chr2	3033401	3034708	+	DDB_G0273505	DDB_G0273505	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273435%22%3EDDB_G0273435%3C%2Fa%3E
chr2	3038057	3039514	-	DDB_G0273509	DDB_G0273509	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273433%22%3EDDB_G0273433%3C%2Fa%3E
chr2	3040382	3041437	-	DDB_G0273511	DDB_G0273511	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273431%22%3EDDB_G0273431%3C%2Fa%3E
chr2	3041831	3043496	-	DDB_G0273513	hpdl-2	catalyzes the reaction 4-hydroxyphenylpyruvate %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E homogentisate %2B CO%3Csub%3E2%3C%2Fsub%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273429%22%3E%3Ci%3Ehpdl-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3044517	3045338	-	DDB_G0273515	DDB_G0273515	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273459%22%3EDDB_G0273459%3C%2Fa%3E
chr2	3046146	3047673	+	DDB_G0273517	abpE-2	involved in pseudopod formation%3B contains an N-terminal ADF%2Fcofilin-like actin binding domain and a c-terminal SH3 domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273447%22%3E%3Ci%3EabpE-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3048030	3048905	+	DDB_G0273519	nit1-2	similar to mammalian NIT1%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273457%22%3E%3Ci%3Enit1-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3048967	3049414	+	DDB_G0273521	DDB_G0273521	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273427%22%3EDDB_G0273427%3C%2Fa%3E
chr2	3050335	3051207	+	DDB_G0273523	rpc25-2	component of the RNA polymerase III complex%3B ortholog of S. cerevisiae RPC25 and H. sapiens RPC8%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273523%22%3E%3Ci%3Erpc25-2%3C%2Fi%3E%3C%2Fa%3E
chr2	3051445	3053533	-	DDB_G0273583	gtf2e1-2	TFIIE large subunit%2C involved in recruitment of RNA polymerase II to the promoter%2C activation of TFIIH%2C and promoter opening%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273525%22%3E%3Ci%3Egtf2e1-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3054694	3055926	+	DDB_G0273527	DDB_G0273527	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273423%22%3EDDB_G0273423%3C%2Fa%3E
chr2	3056199	3058914	-	DDB_G0273529	DDB_G0273529	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273421%22%3EDDB_G0273421%3C%2Fa%3E
chr2	3060166	3062409	+	DDB_G0273531	spkA-2	member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family%3B kinase activity stimulated by hyperosmolarity and heat shock%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273445%22%3E%3Ci%3EspkA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3066091	3067412	+	DDB_G0273533	carA-2	high affinity cAMP receptor%3B belongs to the serpentine%2FG-protein coupled receptor family%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273397%22%3E%3Ci%3EcarA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3068294	3070024	+	DDB_G0273535	mip1-2	physically interacts with and ubiquinates the MAP kinase kinase Mek1 (mekA) and controls its nuclear localization%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273399%22%3E%3Ci%3Emip1-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3070673	3072340	+	DDB_G0273537	DDB_G0273537	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273483%22%3EDDB_G0273483%3C%2Fa%3E 
chr2	3072578	3076565	-	DDB_G0273539	DDB_G0273539	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273419%22%3EDDB_G0273419%3C%2Fa%3E
chr2	3078093	3080328	-	DDB_G0273543	DDB_G0273543	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273481%22%3E%3Ci%3E DDB_G0273481%3C%2Fi%3E%3C%2Fa%3E
chr2	3084342	3086507	+	DDB_G0273545	nfyC-2	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273479%22%3E%3Ci%3EnfyC-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3086765	3088337	-	DDB_G0273547	DDB_G0273547	similar to bacterial S-adenosyl-L-methionine (SAM) methyltransferases%3B similar to D. purpureum protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273417%22%3E%3Ci%3EDDB_G0273417%3C%2Fi%3E%3C%2Fa%3E
chr2	3088869	3089942	+	DDB_G0273549	DDB_G0273549	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273415%22%3EDDB_G0273415%3C%2Fa%3E
chr2	3090095	3091465	-	DDB_G0273551	DDB_G0273551	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273413%22%3E%3Ci%3EDDB_G0273413%3C%2Fi%3E%3C%2Fa%3E
chr2	3092131	3094824	+	DDB_G0273553	atg4-2	ortholog of the conserved ATG4 cysteine protease involved in autophagy%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273443%22%3E%3Ci%3Eatg4-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3095016	3095837	-	DDB_G0273555	DDB_G0273555	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273411%22%3EDDB_G0273411%3C%2Fa%3E 
chr2	3096406	3098235	+	DDB_G0273557	DDB_G0273557	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273477%22%3EDDB_G0273477%3C%2Fa%3E
chr2	3099906	3105209	+	DDB_G0295835	dhkI-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273475%22%3E%3Ci%3EdhkI-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3105660	3109224	+	DDB_G0273559	DDB_G0273559	conserved hypothetical protein%3B similar to esophageal cancer associated protein%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273473%22%3E%3Ci%3EDDB_G0273473%3C%2Fi%3E%3C%2Fa%3E
chr2	3109992	3110693	+	DDB_G0273561	hspF-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273409%22%3E%3Ci%3EhspF-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3111479	3113942	-	DDB_G0273563	dpp3-2	catalyzes the release of an N-terminal dipeptide from a peptide comprising four or more residues%2C with broad specificity%3B highly selective for Arg-Arg-2-naphthylamide%2C at pH 9.2%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273471%22%3E%3Ci%3Edpp3-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3114676	3117570	+	DDB_G0273565	DDB_G0273565	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273453%22%3E%3Ci%3EDDB_G0273453%3C%2Fi%3E%3C%2Fa%3E
chr2	3117781	3118754	-	DDB_G0273569	DDB_G0273569_ps	putative pseudogene%3B similar to coactosin%2C contains an ADF (actin depolymerisation factor%2Fcofilin-like) domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273405%22%3E%3Ci%3EDDB_G0273405_ps%3C%2Fi%3E%3C%2Fa%3E
chr2	3119869	3137068	+	DDB_G0273573	DDB_G0273573	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273451%22%3E%3Ci%3EDDB_G0273451%3C%2Fi%3E%3C%2Fa%3E
chr2	3137655	3137810	-	DDB_G0273575	DDB_G0273575	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273403%22%3EDDB_G0273403%3C%2Fa%3E
chr2	3138626	3139991	+	DDB_G0273577	DDB_G0273577	part of a small Dictyostelium protein family%3B enriched in gametes%3B contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273449%22%3E%3Ci%3EDDB_G0273449%3C%2Fi%3E%3C%2Fa%3E
chr2	3140434	3140991	-	DDB_G0273579	trappc1-2	conserved trafficking protein particle (TRAPP) complex subunit%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273467%22%3Etrappc1-1%3C%2Fa%3E
chr2	3144362	3144553	+	DDB_G0273585	DDB_G0273585	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273255%22%3EDDB_G0273255%3C%2Fa%3E
chr2	3145254	3145400	+	DDB_G0273587	DDB_G0273587	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273395%22%3EDDB_G0273395%3C%2Fa%3E
chr2	3145928	3147088	-	DDB_G0273589	DDB_G0273589	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273253%22%3E%3Ci%3EDDB_G0273253%3C%2Fi%3E%3C%2Fa%3E
chr2	3147334	3148575	-	DDB_G0273591	DDB_G0273591	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273393%22%3E%3Ci%3EDDB_G0273393%3C%2Fi%3E%3C%2Fa%3E
chr2	3150139	3152612	+	DDB_G0273593	DDB_G0273593	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273853%22%3E%3Ci%3E DDB_G0273853%3C%2Fi%3E%3C%2Fa%3E
chr2	3154181	3155997	+	DDB_G0273595	DDB_G0273595	functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC)%3B contains a N-terminal importin beta binding domain (IBB domain)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273149%22%3E%3Ci%3EDDB_G0273149%3C%2Fi%3E%3C%2Fa%3E
chr2	3156381	3157360	+	DDB_G0273597	DDB_G0273597	has similarity to the %3C%2Fi%3ES. cerevisisae%3C%2Fi%3E ATP10%2C a mitochondrial inner membrane protein required for assembly of the mitochondrial F1F0 ATP synthase%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3D DDB_G0273147%22%3E%3Ci%3E DDB_G0273147%3C%2Fi%3E%3C%2Fa%3E
chr2	3157833	3158897	+	DDB_G0273599	DDB_G0273599	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273145%22%3EDDB_G0273145%3C%2Fa%3E
chr2	3159375	3160613	+	DDB_G0273601	sigL-2	regulated by the MADS-box transcription factor SrfA during development%3B expressed in stalk cells%3B contains one EGF domain and a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273261%22%3E%3Ci%3EsigL-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3161301	3161573	+	DDB_G0273603	DDB_G0273603	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273319%22%3EDDB_G0273319%3C%2Fa%3E
chr2	3162717	3164974	+	DDB_G0273605	psiG-2	contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 6 Dictyostelium (CTDC) repeats and a C-terminal transmembrane domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2F%09DDB_G0273389%22%3EpsiG-1%3C%2Fa%3E 
chr2	3165261	3165782	+	DDB_G0273607	DDB_G0273607	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273143%22%3EDDB_G0273143%3C%2Fa%3E
chr2	3166651	3168648	+	DDB_G0273609	cblA-2	homolog of the metazoan cbl proteins%3B contains a tyrosine kinase binding domain (TBK) at the amino terminus connected to a RING finger%3B regulates STAT signaling via PTP3%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273141%22%3E%3Ci%3EcblA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3169189	3170422	+	DDB_G0273611	rad51-2	 ortholog of Rad51%2C which is involved in activation of homologous recombination and double-strand break repair and interacts with XRCC3%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273139%22%3E%3Ci%3Erad51-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3171066	3171890	-	DDB_G0273613	DDB_G0273613	expressed in pstAO cells and in upper cup during culmination%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273387%22%3E%3Ci%3EDDB_G0273387%3C%2Fi%3E%3C%2Fa%3E
chr2	3173987	3174629	+	DDB_G0273615	fpaB-2	component of the SCF ubiquitin ligase complex%3B the fpaB gene encodes a protein almost identical to that of fpaA%2C differing in one amino acid only%3B series of glycosylation reactions attaches a pentasaccharide chain to HyPro143%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273251%22%3E%3Ci%3EfpaB-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3174939	3176999	-	DDB_G0273617	DDB_G0273617	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273137%22%3EDDB_G0273137%3C%2Fa%3E
chr2	3178423	3179870	-	DDB_G0273621	DDB_G0273621	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273315%22%3EDDB_G0273315%3C%2Fa%3E
chr2	3181158	3183056	+	DDB_G0273623	hspE-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273249%22%3E%3Ci%3EhspE-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3184086	3185115	-	DDB_G0273625	DDB_G0273625	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273135%22%3EDDB_G0273135%3C%2Fa%3E
chr2	3185739	3186493	+	DDB_G0273627	DDB_G0273627	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273313%22%3EDDB_G0273313%3C%2Fa%3E
chr2	3187419	3190877	+	DDB_G0273629	DDB_G0273629	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273385%22%3EDDB_G0273385%3C%2Fa%3E
chr2	3191201	3192088	+	DDB_G0273631	cwc15-2	ortholog of S. pombe Cwf15 and S. cerevisiae Cwc15%2C thought to be non-essential components of an mRNA splicing complex%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273383%22%3E%3Ci%3Ecwc15-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3192182	3194872	-	DDB_G0273633	DDB_G0273633	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273133%22%3EDDB_G0273133%3C%2Fa%3E
chr2	3195191	3199942	-	DDB_G0273635	qkgA-2	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains LRR%2C Roc%2C COR%2C and protein kinase domains%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273259%22%3E%3Ci%3EqkgA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3201360	3202092	-	DDB_G0273637	DDB_G0273637	contains no functional domains%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273311%22%3E%3Ci%3EDDB_G0273311%3C%2Fi%3E%3C%2Fa%3E
chr2	3207904	3209791	+	DDB_G0273639	g6pd-2	ortholog of the human G6PD%3B defects in G6PD cause chronic non-spherocytic hemolytic anemia (CNSHA)%3B catalyzes the reaction D-glucose 6-phosphate %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %3D D-glucono-1%2C5-lactone 6-phosphate %2B NADPH %2B H%3Csup%3E%2B%3C%2Fsup%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273131%22%3E%3Ci%3Eg6pd-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3210585	3212963	+	DDB_G0273641	fnkD-2	contains six Dictyostelium-specific FNIP repeats%3B unlikely to function as a kinase as it does not contain a catalytic aspartate%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273129%22%3E%3Ci%3EfnkD-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3213141	3217813	-	DDB_G0273643	DDB_G0273643	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273381%22%3EDDB_G0273381%3C%2Fa%3E
chr2	3218378	3223862	-	DDB_G0273645	hbx5-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273127%22%3E%3Ci%3Ehbx5-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3226059	3229726	-	DDB_G0273647	DDB_G0273647	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273379%22%3EDDB_G0273379%3C%2Fa%3E
chr2	3232367	3237252	+	DDB_G0273651	DDB_G0273651	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273247%22%3EDDB_G0273247%3C%2Fa%3E
chr2	3237347	3240124	-	DDB_G0273653	DDB_G0273653	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273245%22%3EDDB_G0273245%3C%2Fa%3E 
chr2	3240778	3242126	+	DDB_G0273655	DDB_G0273655	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273377%22%3EDDB_G0273377%3C%2Fa%3E
chr2	3242326	3243798	-	DDB_G0273657	vatD-2	ortholog of the D subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the D subunit is part of the V1 subunit%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273071%22%3E%3Ci%3EvatD-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3245894	3246064	-	DDB_G0273659	DDB_G0273659	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273243%22%3EDDB_G0273243%3C%2Fa%3E
chr2	3246689	3246883	-	DDB_G0273661	DDB_G0273661	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273241%22%3EDDB_G0273241%3C%2Fa%3E
chr2	3247453	3248728	-	DDB_G0273663	DDB_G0273663_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273375%22%3EDDB_G0273375%3C%2Fa%3E
chr2	3250010	3250466	-	DDB_G0273667	DDB_G0273667	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273373%22%3EDDB_G0273373%3C%2Fa%3E
chr2	3252529	3256383	-	DDB_G0273669	comF-2	contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273257%22%3E%3Ci%3EcomF-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3258387	3259400	+	DDB_G0273671	DDB_G0273671_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0282843%22%3EDDB_G0282843%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0282839%22%3EDDB_G0282839%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273307%22%3EDDB_G0273307_ps%3C%2Fa%3E 
chr2	3259720	3260877	-	DDB_G0273673	DDB_G0273673	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273237%22%3E%3Ci%3EDDB_G0273237%3C%2Fi%3E%3C%2Fa%3E
chr2	3262518	3266430	+	DDB_G0273675	DDB_G0273675	contains eight transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273235%22%3E%3Ci%3EDDB_G0273235%3C%2Fi%3E%3C%2Fa%3E
chr2	3266679	3267797	+	DDB_G0273677	DDB_G0273677	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273233%22%3EDDB_G0273233%3C%2Fa%3E
chr2	3268768	3271355	+	DDB_G0273679	DDB_G0273679	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273231%22%3EDDB_G0273231%3C%2Fa%3E
chr2	3271631	3275466	-	DDB_G0273681	DDB_G0273681	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273371%22%3EDDB_G0273371%3C%2Fa%3E
chr2	3276482	3276847	-	DDB_G0273685	DDB_G0273685	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273367%22%3EDDB_G0273367%3C%2Fa%3E
chr2	3278808	3280823	-	DDB_G0273687	aslL-2	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273365%22%3E%3Ci%3EaslL-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3283546	3285561	-	DDB_G0273689	aslK-2	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273229%22%3E%3Ci%3EaslK-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3286264	3288281	-	DDB_G0273691	aslJ-2	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273305%22%3E%3Ci%3EaslJ-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3288753	3290289	-	DDB_G0273693	aslI_ps-2	putative pseudogene%3B acetyl-CoA synthetase family protein%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273363%22%3E%3Ci%3EaslI_ps-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3290882	3292902	-	DDB_G0273695	aslI-2	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273227%22%3E%3Ci%3EaslI-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3293184	3295234	-	DDB_G0273697	aslC-2	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273225%22%3E%3Ci%3EaslC-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3295736	3297967	-	DDB_G0273699	aslO-2	similar to bacterial acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273223%22%3E%3Ci%3EaslO-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3298556	3299315	-	DDB_G0273701	DDB_G0273701	conserved protein of unknown function%3B contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273221%22%3E%3Ci%3EDDB_G0273221%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr2	3300432	3301880	+	DDB_G0273703	DDB_G0273703	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273219%22%3EDDB_G0273219%3C%2Fa%3E
chr2	3302300	3302893	+	DDB_G0273705	DDB_G0273705	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273217%22%3EDDB_G0273217%3C%2Fa%3E
chr2	3303396	3304331	+	DDB_G0273707	DDB_G0273707	contains 5 transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273361%22%3E%3Ci%3EDDB_G0273361%3C%2Fi%3E%3C%2Fa%3E
chr2	3304775	3306779	+	DDB_G0273709	aslG-2	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273215%22%3E%3Ci%3EaslG-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3307762	3309767	+	DDB_G0273711	aslG_ps-2	putative pseudogene%3B AMP-dependent synthetase and ligase family protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273359%22%3E%3Ci%3EaslG_ps-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3313316	3313726	+	DDB_G0273715	aslE_ps-2	putative pseudogene%3B AMP-dependent synthetase and ligase family protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273303%22%3E%3Ci%3EaslE_ps-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3313863	3315894	+	DDB_G0273717	aslD-2	similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273211%22%3E%3Ci%3EaslD-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3316025	3320736	-	DDB_G0273719	trappc10-2	ortholog of the trafficking protein particle complex subunit 10%2C part of the multisubunit TRAPP (transport protein particle) complex%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273209%22%3E%3Ci%3Etrappc10-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3321422	3323747	-	DDB_G0273721	cdk9-2	similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273207%22%3E%3Ci%3Ecdk9-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3324668	3327700	-	DDB_G0273723	DDB_G0273723	contains an EF hand but shows little similarity to other proteins%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273205%22%3E%3Ci%3EDDB_G0273205%3C%2Fi%3E%3C%2Fa%3E
chr2	3329319	3330893	+	DDB_G0273725	snf12-2	nuclear protein and ortholog of yeast SNF12 and human SMARCD1 that are involved in chromatin remodeling%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273203%22%3E%3Ci%3Esnf12-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3331134	3331943	-	DDB_G0273727	DDB_G0273727	similar to MAD2 and REV7%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273201%22%3E%3Ci%3EDDB_G0273201%3C%2Fi%3E%3C%2Fa%3E
chr2	3332122	3333552	-	DDB_G0273729	mkpB-2	putative  protein tyrosine phosphatase%3B similar to the cofilin phosphatase slingshot and to other dual-specificity phosphatases%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273199%22%3E%3Ci%3EmkpB-1%3C%2Fi%3E%3C%2Fa%3E%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E The single Dicty homologue of the cofilin phosphatase slingshot.
chr2	3334723	3335690	+	DDB_G0273731	alyD-2	member of a new lysozyme class%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273731%22%3E%3Ci%3EalyD-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	3336611	3338682	+	DDB_G0273733	DDB_G0273733	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273357%22%3E%3Ci%3EDDB_G0273357%3C%2Fi%3E%3C%2Fa%3E
chr2	3339316	3341079	+	DDB_G0273735	DDB_G0273735	member of the major facilitator superfamily (MFS)%3B expressed in upper cup during culmination%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273195%22%3E%3Ci%3EDDB_G0273195%3C%2Fi%3E%3C%2Fa%3E
chr2	3341355	3342965	-	DDB_G0273737	cak1-2	protein serine%2Fthreonine kinase%2C CK1 family%3B similar to human CK1 and yeast YCK%3B may play a role in DNA repair%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273059%22%3E%3Ci%3Ecak1-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3345112	3347069	+	DDB_G0273739	DDB_G0273739	shares a short region of similarity with the human gene TEX2 (expressed in testis)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273193%22%3E%3Ci%3EDDB_G0273193%3C%2Fi%3E%3C%2Fa%3E
chr2	3347298	3348386	-	DDB_G0273741	rexo2-2	similar to H. sapiens REXO2 and S. cerevisiae REX2%2C a mitochondrial 3%27-5%27 RNA exonuclease%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273355%22%3E%3Ci%3Erexo2-1%3C%2Fi%3E%3C%2Fa%3E   
chr2	3349136	3349937	+	DDB_G0273743	rps30-2	protein component of the small (40S) ribosomal subunit%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273191%22%3E%3Ci%3Erps30-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3350147	3352651	-	DDB_G0273745	DDB_G0273745	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273189%22%3E%3Ci%3EDDB_G0273189%3C%2Fi%3E%3C%2Fa%3E
chr2	3353701	3353892	-	DDB_G0273747	DDB_G0273747	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273187%22%3E%09DDB_G0273187%3C%2Fa%3E
chr2	3354615	3358265	-	DDB_G0273749	DDB_G0273749	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273185%22%3EDDB_G0273185%3C%2Fa%3E
chr2	3358648	3360140	-	DDB_G0273751	fnkG_ps-2	putative pseudogene%3B STE%2FFNIP protein kinase family%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273353%22%3E%3Ci%3EfnkG_ps-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3360515	3363060	+	DDB_G0273753	DDB_G0273753	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273301%22%3EDDB_G0273301%3C%2Fa%3E
chr2	3363343	3368673	+	DDB_G0273755	DDB_G0273755	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273351%22%3EDDB_G0273351%3C%2Fa%3E
chr2	3368962	3369033	-	DDB_G0294995	tRNA-Thr-AGU-15	transfers a threonine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294843%22%3E%3Ci%3EtRNA-Thr-AGU-13%3C%2Fi%3E%3C%2Fa%3E 
chr2	3369078	3369849	+	DDB_G0273757	cyp518A2_ps-2	putative pseudogene%3B related to the cytochrome P450 family%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273349%22%3E%3Ci%3Ecyp518A2_ps-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3370120	3370202	-	DDB_G0294993	tRNA-Leu-UAA-6	transfers a leucine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294841%22%3E%3Ci%3EtRNA-Leu-UAA-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3371993	3373327	+	DDB_G0273759	DDB_G0273759_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273347%22%3E%3Ci%3EDDB_G0273347_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	3373618	3376761	+	DDB_G0273761	DDB_G0273761_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273345%22%3E%3Ci%3EDDB_G0273345_RTE%3Ci%2F%3E%3C%2Fa%3E
chr2	3377741	3379158	-	DDB_G0273763	DDB_G0273763	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273299%22%3EDDB_G0273299%3C%2Fa%3E
chr2	3379796	3383938	+	DDB_G0273765	DDB_G0273765	there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273075%22%3E%3Ci%3EDDB_G0273075%3C%2Fi%3E%3C%2Fa%3E
chr2	3384122	3385753	-	DDB_G0273767	DDB_G0273767	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273077%22%3EDDB_G0273077%3C%2Fa%3E
chr2	3387269	3387893	-	DDB_G0273769	DDB_G0273769	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273297%22%3EDDB_G0273297%3C%2Fa%3E 
chr2	3388529	3389023	+	DDB_G0273771	DDB_G0273771	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273295%22%3EDDB_G0273295%3C%2Fa%3E
chr2	3389376	3389852	-	DDB_G0273773	DDB_G0273773	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273079%22%3E%3Ci%3EDDB_G0273079%3C%2Fi%3E%3C%2Fa%3E
chr2	3390843	3391711	-	DDB_G0273775	cinD-2	ortholog of Saccharomyces cerevisiae Mbf1 protein%3B expressed at high level in vegetative celly and decreases sharply in early development%3B induced by cycloheximide%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273061%22%3E%3Ci%3EcinD-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3392002	3393159	+	DDB_G0273777	DDB_G0273777	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273343%22%3EDDB_G0273343%3C%2Fa%3E 
chr2	3394303	3395715	+	DDB_G0273779	DDB_G0273779	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273293%22%3E%3Ci%3EDDB_G0273293%3C%2Fi%3E%3C%2Fa%3E
chr2	3396905	3401522	+	DDB_G0273781	abcG17-2	full transporter%2C consisting of two ABC domains and two transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273073%22%3E%3Ci%3EabcG17-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3402431	3403471	+	DDB_G0273783	ddo-1	catalyzes the oxidation of neutral and basic D-amino acids into their corresponding keto acids%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273291%22%3E%3Ci%3Eddo-2%3C%2Fi%3E%3C%2Fa%3E
chr2	3404067	3404843	+	DDB_G0273785	DDB_G0273785	no homologs in other organisms%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273289%22%3E%3Ci%3EDDB_G0273289%3C%2Fi%3E%3C%2Fa%3E  
chr2	3405130	3406719	-	DDB_G0273787	DDB_G0273787	similar to histidine ammonia-lyase%2C which catalyzes the reaction L-histidine %3D urocanate %2B NH%3Csub%3E3%3C%2Fsub%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273081%22%3E%3Ci%3EDDB_G0273081%3C%2Fi%3E%3C%2Fa%3E
chr2	3407290	3408210	+	DDB_G0273789	DDB_G0273789	member of the Dyp-type peroxidase family lacking a typical heme-binding region%3B does not appear to be present in higher organisms%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273083%22%3E%3Ci%3EDDB_G0273083%3C%2Fi%3E%3C%2Fa%3E
chr2	3408281	3409867	-	DDB_G0273791	DDB_G0273791	contains a predicted signal peptide%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273085%22%3EDDB_G0273085%3C%2Fa%3E
chr2	3410837	3418257	+	DDB_G0273795	DDB_G0273795	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273285%22%3E%3Ci%3E DDB_G0273285%3C%2Fi%3E%3C%2Fa%3E
chr2	3418714	3418895	-	DDB_G0273797	DDB_G0273797	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273341%22%3EDDB_G0273341%3C%2Fa%3E
chr2	3419302	3419526	-	DDB_G0273799	DDB_G0273799	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273183%22%3EDDB_G0273183%3C%2Fa%3E
chr2	3420827	3426565	+	DDB_G0273801	DDB_G0273801_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0290841%22%3EDDB_G0290841%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0287167%22%3EDDB_G0287167%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273087%22%3E%3Ci%3EDDB_G0273087%3C%2Fi%3E%3C%2Fa%3E
chr2	3426934	3427636	+	DDB_G0273803	coq10-2	ortholog of the conserved COQ10%2C a Coenzyme Q (ubiquinone) binding protein in %3Ci%3ES. cerevisiae%3C%2Fi%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273089%22%3E%3Ci%3Ecoq10-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3427961	3428694	+	DDB_G0273805	ndkC-2	catalyzes the phosphorylation of nucleoside or deoxynucleoside diphosphates into the corresponding triphosphates%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273069%22%3E%3Ci%3EndkC-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3428943	3429210	-	DDB_G0273807	DDB_G0273807	contains no functional domains and is not similar to any other protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273181%22%3E%3Ci%3EDDB_G0273181%3C%2Fi%3E%3C%2Fa%3E
chr2	3430856	3432069	-	DDB_G0273809	DDB_G0273809	member of the ZIP (Zrt- and Irt-like Protein) family capable of transporting zinc and other metal ions%3B contains 6 transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273091%22%3E%3Ci%3EDDB_G0273091%3C%2Fi%3E%3C%2Fa%3E
chr2	3433152	3436690	+	DDB_G0273811	DDB_G0273811	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273339%22%3EDDB_G0273339%3C%2Fa%3E
chr2	3437085	3440304	+	DDB_G0273813	DDB_G0273813	similar to the mammalian Hypoxia up-regulated protein 1 (HYOU1)%2C a protein that plays a role in cytoprotective cellular mechanisms triggered by oxygen deprivation%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273093%22%3E%3Ci%3EDDB_G0273093%3C%2Fi%3E%3C%2Fa%3E
chr2	3440428	3441054	-	DDB_G0273815	DDB_G0273815	similar to human PDAP1 (PDGFA-associated protein 1)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273095%22%3E %3Ci%3EDDB_G0273095%3C%2Fi%3E%3C%2Fa%3E
chr2	3443306	3445076	+	DDB_G0273817	ptpA1-2	 there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?dictybaseid%3DDDB0185117%22%3E%3Ci%3EptpA1-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3445587	3447092	+	DDB_G0273819	DDB_G0273819	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273179%22%3EDDB_G0273179%3C%2Fa%3E
chr2	3447237	3447804	-	DDB_G0273821	DDB_G0273821	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273283%22%3EDDB_G0273283%3C%2Fa%3E
chr2	3448973	3450406	+	DDB_G0273823	DDB_G0273823	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273281%22%3EDDB_G0273281%3C%2Fa%3E
chr2	3450554	3451321	-	DDB_G0273825	rsmE-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273099%22%3E%3Ci%3ErsmE-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3452373	3453482	-	DDB_G0273827	DDB_G0273827	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273279%22%3EDDB_G0273279%3C%2Fa%3E
chr2	3454255	3455902	+	DDB_G0273829	DDB_G0273829	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273277%22%3EDDB_G0273277%3C%2Fa%3E
chr2	3456169	3462721	-	DDB_G0273831	DDB_G0273831	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273101%22%3E%3Ci%3EDDB_G0273101%3C%2Fi%3E%3C%2Fa%3E
chr2	3463611	3465086	+	DDB_G0273833	DDB_G0273833	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273275%22%3EDDB_G0273275%3C%2Fa%3E
chr2	3465226	3466020	-	DDB_G0273835	DDB_G0273835	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273103%22%3EDDB_G0273103%3C%2Fa%3E
chr2	3466919	3469700	-	DDB_G0273837	scdB-2	contains a cytochrome b5 domain%3B introduces a double bond at the delta position of fatty acids during the biosynthesis of monounsaturated fatty acids%3B there is a second copy of this gene %3Ca href%3D%22%2Fgene%2FDDB_G0273105%22%3E%3Ci%3EscdB-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3471006	3477456	-	DDB_G0273839	fip-2	interacts with filamin (abpC) and plays a role in development and phototaxis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2FgeneDDB_G0273107%22%3E%3Ci%3Efip-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3478561	3479737	+	DDB_G0273841	DDB_G0273841	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273109%22%3EDDB_G0273109%3C%2Fa%3E
chr2	3480800	3481378	+	DDB_G0273843	DDB_G0273843	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273273%22%3E%3Ci%3E DDB_G0273273%3C%2Fi%3E%3C%2Fa%3E
chr2	3482185	3482388	+	DDB_G0273845	DDB_G0273845_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0273799%22%3EDDB_G0273799%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273337%22%3EDDB_G0273337_ps%3C%2Fa%3E
chr2	3483399	3483608	+	DDB_G0273849	DDB_G0273849	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273111%22%3EDDB_G0273111%3C%2Fa%3E
chr2	3484397	3485149	+	DDB_G0273851	DDB_G0273851	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273113%22%3EDDB_G0273113%3C%2Fa%3E
chr2	3485257	3485787	-	DDB_G0273853	DDB_G0273853	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273115%22%3E%3Ci%3E DDB_G0273115%3C%2Fi%3E%3C%2Fa%3E
chr2	3486160	3487074	+	DDB_G0273855	DDB_G0273855	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0295833%22%3E%3Ci%3EDDB_G0295833%3C%2Fi%3E%3C%2Fa%3E
chr2	3487559	3491984	+	DDB_G0273857	irlB-2	putative protein serine%2Fthreonine kinase%3B the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273333%22%3E%3Ci%3EirlB-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3492274	3492930	-	DDB_G0273859	DDB_G0273859	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273331%22%3EDDB_G0273331%3C%2Fa%3E
chr2	3493474	3494770	-	DDB_G0273861	ublcp1-2	ortholog of the H. sapiens UBLCP1%2C a conserved protein that contains a ubiquitin and a NLI interacting factor domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273117%22%3E%3Ci%3Eublcp1-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3495454	3495896	+	DDB_G0273863	DDB_G0273863	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273119%22%3EDDB_G0273119%3C%2Fa%3E
chr2	3497296	3499044	-	DDB_G0273865	pakH-2	putative protein serine%2Fthreonine kinase%3B similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B belongs to the PAKL subfamilystress-responsive kinase%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?dictybaseid%3DDDB0229408%22%3EpakH-1 %3C%2Fa%3E
chr2	3499369	3500451	-	DDB_G0273867	DDB_G0273867	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273123%22%3EDDB_G0273123%3C%2Fa%3E
chr2	3501162	3503366	+	DDB_G0273869	DDB_G0273869	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273125%22%3EDDB_G0273125%3C%2Fa%3E 
chr2	3504469	3505086	+	DDB_G0273871	DDB_G0273871	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273177%22%3EDDB_G0273177%3C%2Fa%3E
chr2	3505655	3507927	+	DDB_G0273873	DDB_G0273873	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273151%22%3EDDB_G0273151%3C%2Fa%3E
chr2	3508572	3509483	-	DDB_G0273875	cf50-2	component of the counting factor complex%2C which includes CF60%2C CF50%2C CF45-1%2C and CtnA (countin)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273175%22%3E%3Ci%3Ecf50-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3510436	3511039	-	DDB_G0273877	DDB_G0273877_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273329%22%3E%3Ci%3EDDB_G0273329_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	3511146	3513731	-	DDB_G0273879	DDB_G0273879_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273327%22%3E%3Ci%3EDDB_G0273327_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	3513881	3514762	-	DDB_G0273881	DDB_G0273881_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273325%22%3E%3Ci%3EDDB_G0273325_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	3515045	3516878	-	DDB_G0273883	DDB_G0273883_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273271%22%3E%3Ci%3EDDB_G0273271_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	3515101	3515172	-	DDB_G0294991	tRNA-Met-CAU-10	transfers a methionine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294839%22%3E%3Ci%3EtRNA-Met-CAU-5%3C%2Fi%3E%3C%2Fa%3E 
chr2	3518508	3518579	+	DDB_G0294845	tRNA-Met-CAU-6	transfers a methionine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294997%22%3E%3Ci%3EtRNA-Met-CAU-11%3C%2Fi%3E%3C%2Fa%3E 
chr2	3519560	3520321	+	DDB_G0273885	dscC-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273065%22%3E%3Ci%3EdscC-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3521045	3521806	+	DDB_G0273887	dscD-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273067%22%3E%3Ci%3EdscD-1%3C%2Fi%3E%3C%2Fa%3E  
chr2	3522887	3523349	+	DDB_G0273889	DDB_G0273889_ps	putative pseudogene%3B fragment%2C similar to UNC93-like protein MFSD11 family members %3Ca href%3D%22%2Fgene%2FDDB_G0291720%22%3EDDB_G0291720%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0291722%22%3EDDB_G0291722%3C%2Fa%3E%3B%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273269%22%3EDDB_G0273269%3C%2Fa%3E
chr2	3524835	3524913	+	DDB_G0294847	tRNA-Leu-UAG-1	transfers a leucine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294999%22%3E%3Ci%3EtRNA-Leu-UAG-2%3C%2Fi%3E%3C%2Fa%3E 
chr2	3525631	3525780	+	DDB_G0348648	dsc_ps2	putative pseudogene%3B short fragment%3B similar to D. discoideum discoidin gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0273065%22%3E%3Ci%3EdscC-1%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0273067%22%3E%3Ci%3EdscD-1%3C%2Fi%3E%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0348645%22%3E%3Ci%3Edsc_ps1%3C%2Fi%3E%3C%2Fa%3E
chr2	3526533	3528833	-	DDB_G0273893	DDB_G0273893	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273173%22%3EDDB_G0273173%3C%2Fa%3E
chr2	3531220	3532959	-	DDB_G0273895	DDB_G0273895	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273169%22%3EDDB_G0273169%3C%2Fa%3E
chr2	3533566	3533637	-	DDB_G0294989	tRNA-Glu-UUC-10	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294837%22%3E%3Ci%3EtRNA-Glu-UUC-7%3C%2Fi%3E%3C%2Fa%3E 
chr2	3533786	3534650	+	DDB_G0273897	DDB_G0273897_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273323%22%3E%3Ci%3EDDB_G0273323_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	3535904	3536236	+	DDB_G0273899	DDB_G0273899	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273265%22%3EDDB_G0273265%3C%2Fa%3E
chr2	3536552	3539488	+	DDB_G0273901	DDB_G0273901_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273263%22%3E%3Ci%3EDDB_G0273263_RTE%3C%2Fi%3E%3C%2Fa%3E
chr2	3539698	3539771	-	DDB_G0294987	tRNA-Phe-GAA-8	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294835%22%3E%3Ci%3EtRNA-Phe-GAA-3%3C%2Fi%3E%3C%2Fa%3E 
chr2	3540442	3544951	-	DDB_G0273903	irlF-2	putative protein serine%2Fthreonine kinase%3B the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273171%22%3E%3Ci%3EirlF-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3545738	3546181	+	DDB_G0273905	DDB_G0273905	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273167%22%3EDDB_G0273167%3C%2Fa%3E
chr2	3546510	3547587	+	DDB_G0273907	DDB_G0273907	catalyses the endonucleolytic cleavage of apurinic or apyrimidinic sites to generate products with a 5%27-phosphate%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273165%22%3E%3Ci%3EDDB_G0273165%3C%2Fi%3E%3C%2Fa%3E
chr2	3547766	3549007	-	DDB_G0273909	psmB4-2	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273163%22%3E%3Ci%3EpsmB4-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3549347	3550076	-	DDB_G0273911	DDB_G0273911	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273161%22%3EDDB_G0273161%3C%2Fa%3E
chr2	3551204	3551419	-	DDB_G0273913	DDB_G0273913	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273159%22%3EDDB_G0273159%3C%2Fa%3E
chr2	3551741	3552754	-	DDB_G0273915	iliE-2	induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273157%22%3E%3Ci%3EiliE-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3553792	3555544	+	DDB_G0273917	DDB_G0273917	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273321%22%3EDDB_G0273321%3C%2Fa%3E
chr2	3556412	3557173	+	DDB_G0273919	dscA-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273063%22%3E%3Ci%3EdscA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3558114	3559347	+	DDB_G0273921	DDB_G0273921	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273155%22%3E%3Ci%3EDDB_G0273155%3C%2Fi%3E%3C%2Fa%3E
chr2	3561472	3562229	-	DDB_G0273923	DDB_G0273923	weakly similar to glutathione S-transferases%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273153%22%3E%3Ci%3EDDB_G0273153%3C%2Fi%3E%3C%2Fa%3E
chr2	3564872	3565597	+	DDB_G0273927	DDB_G0273927	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272576%22%3EDDB_G0272576%3C%2Fa%3E
chr2	3567518	3568581	+	DDB_G0273929	DDB_G0273929_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0273933%22%3EDDB_G0273933%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0273049%22%3EDDB_G0273049%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272907%22%3EDDB_G0272907_ps%3C%2Fa%3E
chr2	3569600	3570651	+	DDB_G0273933	DDB_G0273933	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273049%22%3EDDB_G0273049%3C%2Fa%3E
chr2	3571468	3572486	+	DDB_G0273935	rabF1-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272905%22%3E%3Ci%3ErabF1-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3572851	3573435	+	DDB_G0273937	DDB_G0273937	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272572%22%3EDDB_G0272572%3C%2Fa%3E
chr2	3574169	3574855	+	DDB_G0273939	DDB_G0273939	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272570%22%3EDDB_G0272570%3C%2Fa%3E
chr2	3575667	3577533	+	DDB_G0273941	cyp508A3-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273047%22%3E%3Ci%3Ecyp508A3-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3578372	3580384	+	DDB_G0273943	cyp508A1-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273045%22%3E%3Ci%3Ecyp508A1-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3580950	3582749	+	DDB_G0273945	cyp508A2-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272604%22%3E%3Ci%3Ecyp508A2-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3582853	3584506	-	DDB_G0273947	DDB_G0273947	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272602%22%3EDDB_G0272602%3C%2Fa%3E
chr2	3584650	3588607	-	DDB_G0273949	DDB_G0273949	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272807%22%3EDDB_G0272807%3C%2Fa%3E
chr2	3589328	3594050	+	DDB_G0273951	DDB_G0273951	ortholog of human HPS5%3B mutations in human HPS5 have been linked to Hermansky-Pudlak syndrome 5%3B contains a putative RING Zn finger%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272600%22%3E%3Ci%3EDDB_G0272600%3C%2Fi%3E%3C%2Fa%3E
chr2	3594233	3596260	-	DDB_G0273953	DDB_G0273953	hypothetical protein%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272903%22%3E%3Ci%3EDDB_G0272903%3C%2Fi%3E%3C%2Fa%3E
chr2	3597027	3601879	+	DDB_G0273955	DDB_G0273955	conserved Dictyostelium protein%3B contains a weak putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272901%22%3E%3Ci%3EDDB_G0272901%3C%2Fi%3E%3C%2Fa%3E
chr2	3604314	3605927	+	DDB_G0273959	DDB_G0273959_ps	putative pseudogene%2C similar to to a large family of EGF like domain-containing proteins%3B there is a second copy of this pseudogene%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0272598%22%3E%3Ci%3EDDB_G0272598_ps%3C%2Fi%3E%3C%2Fa%3E
chr2	3606161	3610989	-	DDB_G0273961	DDB_G0273961	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273043%22%3E%3Ci%3EDDB_G0273043%3C%2Fi%3E%3C%2Fa%3E
chr2	3612304	3612695	+	DDB_G0273963	DDB_G0273963	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272596%22%3EDDB_G0272596%3C%2Fa%3E
chr2	3613046	3617571	-	DDB_G0273965	DDB_G0273965	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272897%22%3E%3Ci%3EDDB_G0272897%3C%2Fi%3E%3C%2Fa%3E
chr2	3618473	3622976	-	DDB_G0273967	DDB_G0273967	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272805%22%3E%3Ci%3EDDB_G0272805%3C%2Fi%3E%3C%2Fa%3E
chr2	3623393	3623623	-	DDB_G0273969	DDB_G0273969	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272803%22%3EDDB_G0272803%3C%2Fa%3E
chr2	3624846	3626439	+	DDB_G0273973	DDB_G0273973_ps	putative pseudogene%3B very similar to the putative importin subunit alpha C gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0277993%22%3EDDB_G0277993%3C%2Fa%3E%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272594%22%3EDDB_G0272594%3C%2Fa%3E
chr2	3626926	3631521	-	DDB_G0273975	DDB_G0273975	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272592%22%3E%3Ci%3EDDB_G0272592%3C%2Fi%3E%3C%2Fa%3E
chr2	3632343	3632892	+	DDB_G0273977	srp14-2	component of the signal recognition particle (SRP)%2C which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulum%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272590%22%3E%3Ci%3Esrp14-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3633103	3634222	-	DDB_G0273979	psmD8-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272564%22%3E%3Ci%3EpsmD8-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3634594	3634998	-	DDB_G0273981	dpm2-2	highly conserved protein involved in GPI biosynthesis%3B forms a complex with DPM1 and DPM3%3B regulates the biosynthesis of dolichol-phosphate-mannose%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272588%22%3E%3Ci%3Edpm2-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3635653	3636524	+	DDB_G0273983	rpl15-2	protein component of the large (60S) ribosomal subunit%3Bthere is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272893%22%3E%3Ci%3Erpl15-1%3C%2Fi%3E%3C%2Fa%3E 
chr2	3636917	3639205	+	DDB_G0273985	DDB_G0273985	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272801%22%3EDDB_G0272801%3C%2Fa%3E
chr2	3639322	3639957	-	DDB_G0273987	DDB_G0273987_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0272586%22%3EDDB_G0272586%3C%2Fa%3E%3B there is a second copy of this pseudogene %3Ca href%3D%22%2Fgene%2FDDB_G0272891%22%3E%3Ci%3EDDB_G0272891%3C%2Fi%3E%3C%2Fa%3E
chr2	3640497	3641351	-	DDB_G0273989	DDB_G0273989	expressed in prespore cells%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272586%22%3E%3Ci%3EDDB_G0272586%3C%2Fi%3E%3C%2Fa%3E
chr2	3641808	3643314	-	DDB_G0273991	maoC-2	catalyzes the reaction RCH%3Csub%3E2%3C%2Fsub%3ENH%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3D RCHO %2B ammonia %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3B acts on primary amines%2C as well as on some secondary and tertiary amines%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272584%22%3E%3Ci%3EmaoC-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3644879	3646423	-	DDB_G0273993	maoB-2	catalyzes the reaction RCH%3Csub%3E2%3C%2Fsub%3ENH%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3D RCHO %2B ammonia %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3B acts on primary amines%2C as well as on some secondary and tertiary amines%3B  there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272582%22%3E%3Ci%3EmaoB-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3647566	3648368	+	DDB_G0273995	icmA-2	carries out carboyxl methylation of cleaved eukaryotic proteins that terminate in a CaaX motif such as NE81 (lmnB)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272799%22%3E%3Ci%3EicmA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3648910	3650253	+	DDB_G0273997	DDB_G0273997	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273041%22%3EDDB_G0273041%3C%2Fa%3E
chr2	3650442	3651343	-	DDB_G0273999	DDB_G0273999	similar to human RWDD1%2C S. cerevisiae GIR2%3B S. cerevisiae GIR2 binds to and regulates the expression of GTP-binding protein DRG2%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272580%22%3E%3Ci%3EDDB_G0272580%3C%2Fi%3E%3C%2Fa%3E
chr2	3651662	3652474	+	DDB_G0274001	surf1-2	ortholog of SURF1%2C encoding a factor involved in the biogenesis of cytochrome c oxidase%2C mutated in Leigh syndrome%3B there is a second copy of this gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272889%22%3E%3Ci%3Esurf1-1%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr2	3652959	3656891	+	DDB_G0274003	ap3b-2	there is a second copy of this gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272578%22%3E%3Ci%3Eap3b-1%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr2	3660427	3662818	+	DDB_G0274007	DDB_G0274007	similar to cyclin dependent protein kinases%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272797%22%3E%3Ci%3EDDB_G0272797%3C%2Fi%3E%3C%2Fa%3E
chr2	3662811	3664424	+	DDB_G0274009	DDB_G0274009	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272622%22%3E%09DDB_G0272622%3C%2Fa%3E
chr2	3664882	3667419	-	DDB_G0274011	fslJ-2	identified as a suppressor of smlA null mutant cnr1%3B putative cell number regulator%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272885%22%3E%3Ci%3EfslJ-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3667910	3668434	-	DDB_G0274013	DDB_G0274013	similar to human HSBP1%3B HSBP1 is a negative regulator of the heat shock response%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272620%22%3E%3Ci%3EDDB_G0272620%3C%2Fi%3E%3C%2Fa%3E
chr2	3668724	3669931	+	DDB_G0274015	ksrA-2	catalyzes the reduction of sphinganine to 3-dehydrosphinganine in glycosphingolipid metabolism%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272883%22%3E%3Ci%3EksrA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3669962	3671500	-	DDB_G0274017	iptC-2	IPP transferases modify both cytoplasmic and mitochondrial tRNAs at A(37) to give isopentenyl A(37)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274017%22%3E%3Ci%3EiptC-2%3C%2Fi%3E%3C%2Fa%3E
chr2	3671700	3673811	-	DDB_G0274019	tkt-2	catalyzes the reaction D-ribose-5-phosphate %2B D-xylulose-5-phosphate %3C%3D%3E D-sedoheptulose-7-phosphate %2B D-glyceraldehyde-3-phosphate%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272618%22%3E%3Ci%3Etkt-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3674573	3675875	-	DDB_G0274021	rnrB-2	catalyzes the reaction 2%27-deoxyribonucleoside diphosphate %2B thioredoxin disulfide %2B H%3Csub%3E2%3C%2Fsub%3EO %3D ribonucleoside diphosphate %2B reduced thioredoxin%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272616%22%3E%3Ci%3ErnrB-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3677221	3678222	+	DDB_G0274023	capA-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272560%22%3E%3Ci%3EcapA-1%3C%2Fi%3E%3C%2Fa%3E %3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with cap%2C the cyclase-associated protein protein
chr2	3678442	3678995	+	DDB_G0274025	DDB_G0274025	similar to the THAP domain in the mammalian THAP domain-containing protein 4%3B underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants%3B%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272614%22%3E%3Ci%3EDDB_G0272614%3C%2Fi%3E%3C%2Fa%3E 
chr2	3679259	3681101	-	DDB_G0274027	DDB_G0274027	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272612%22%3EDDB_G0272612%3C%2Fa%3E
chr2	3681740	3685607	-	DDB_G0274029	ptcJ-2	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273037%22%3EptcJ-1%3C%2Fa%3E
chr2	3686525	3688878	+	DDB_G0274031	DDB_G0274031	weakly similar to glycoproteins GP138A-D and gp130%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272610%22%3E%3Ci%3EDDB_G0272610%3C%2Fi%3E%3C%2Fa%3E
chr2	3690459	3692641	+	DDB_G0274033	fslM-2	has similarity to G-protein-coupled receptors%3B predicted to have 7 transmembrane domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273035%22%3E%3Ci%3EfslM-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3693611	3696390	+	DDB_G0274035	stip-2	conserved protein%2C ortholog of the %3Ci%3ED. melanogaster%3C%2Fi%3E sip1 gene (septin interaction protein) and to the %3Ci%3EH. sapiens%3C%2Fi%3E tuftelin-interacting protein 11 (TFIP11)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272608%22%3E%3Ci%3Estip-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3696537	3697394	-	DDB_G0274037	DDB_G0274037	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272606%22%3EDDB_G0272606%3C%2Fa%3E 
chr2	3697844	3698798	+	DDB_G0274039	DDB_G0274039	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272939%22%3E%3Ci%3EDDB_G0272939 %3C%2Fi%3E%3C%2Fa%3E%3B has also similarity to hypothetical proteins in other organisms%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272881%22%3E%3Ci%3EDDB_G0272881%3C%2Fi%3E%3C%2Fa%3E 
chr2	3698912	3703728	-	DDB_G0274041	DDB_G0274041	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273033%22%3E%3Ci%3EDDB_G0273033%3C%2Fi%3E%3C%2Fa%3E  
chr2	3708092	3708886	-	DDB_G0274043	DDB_G0274043	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273031%22%3EDDB_G0273031%3C%2Fa%3E
chr2	3709694	3710435	+	DDB_G0274045	3B-2	expressed in prespore cells%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272795%22%3E%3Ci%3E3B-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3711697	3712054	+	DDB_G0274047	DDB_G0274047	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272879%22%3EDDB_G0272879%3C%2Fa%3E 
chr2	3712319	3713995	-	DDB_G0274049	DDB_G0274049	contains 4 coiled-coil domains%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272877%22%3EDDB_G0272877%3C%2Fa%3E
chr2	3715266	3717085	+	DDB_G0274051	cpnB-2	Ca(2%2B)-dependent phospholipid-binding protein%3B contains two C2 domains and a VWFA domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272875%22%3E%3Ci%3EcpnB-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3717731	3718126	+	DDB_G0274053	DDB_G0274053	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272650%22%3EDDB_G0272650%3C%2Fa%3E
chr2	3718398	3719265	-	DDB_G0274055	DDB_G0274055	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272648%22%3EDDB_G0272648%3C%2Fa%3E 
chr2	3719728	3720144	+	DDB_G0274057	cofD-2	very similar to cofC and similar to cofA%2C a 15 kDa protein with actin filament severing activity%3B contains an actin-binding%2C cofilin%2Ftropomyosin type domain%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272646%22%3E%3Ci%3EcofD-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3720546	3720977	+	DDB_G0274059	cofC-2	a new member of the cofilin family%2C specifically expressed during aggregation%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272568%22%3E%3Ci%3EcofC-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3721083	3722555	-	DDB_G0274061	DDB_G0274061	contains 3 FNIP repeats%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272644%22%3EDDB_G0272644%3C%2Fa%3E
chr2	3722937	3724499	-	DDB_G0274063	DDB_G0274063	there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272642%22%3E%3Ci%3EDDB_G0272642%3C%2Fi%3E%3C%2Fa%3E
chr2	3726636	3727463	+	DDB_G0274065	DDB_G0274065	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272640%22%3EDDB_G0272640%3C%2Fa%3E
chr2	3730947	3734597	+	DDB_G0274067	DDB_G0274067	PIP5K catalyze the formation of phosphoinositol-4%2C5-bisphosphate via the phosphorylation of phosphatidylinositol-4-phosphate%2C a precursor in the phosphinositide signaling pathway%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272638%22%3E%3Ci%3EDDB_G0272638%3C%2Fi%3E%3C%2Fa%3E
chr2	3734831	3736051	-	DDB_G0274069	DDB_G0274069	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272636%22%3EDDB_G0272636%3C%2Fa%3E
chr2	3736604	3737053	+	DDB_G0274071	DDB_G0274071	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273029%22%3EDDB_G0273029%3C%2Fa%3E
chr2	3737258	3738394	+	DDB_G0274073	DDB_G0274073	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0273027%22%3EDDB_G0273027%3C%2Fa%3E
chr2	3738689	3743245	+	DDB_G0274075	DDB_G0274075	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273053%22%3E%3Ci%3EDDB_G0273053%3C%2Fi%3E%3C%2Fa%3E 
chr2	3743727	3747469	+	DDB_G0274077	drnA-2	similar to the mammalian Dicer protein%2C an RNase III protein that converts long dsRNA (double-stranded RNA) into siRNA (small interfering RNA)%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273051%22%3E%3Ci%3EdrnA-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3747735	3748763	+	DDB_G0274079	dohh-2	ortholog of H. sapiens DOHH%2C that catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine%2C an essential post-translational modification only found in mature eIF5A factor%3B the first reaction is catalyzed by Dhps%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272634%22%3E%3Ci%3Edohh-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3748941	3749724	-	DDB_G0274081	DDB_G0274081	catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione%3B there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272632%22%3E%3Ci%3EDDB_G0272632%3C%2Fi%3E%3C%2Fa%3E
chr2	3750393	3751194	+	DDB_G0274083	DDB_G0274083	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272630%22%3EDDB_G0272630%3C%2Fa%3E
chr2	3751889	3753008	+	DDB_G0274085	DDB_G0274085	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants%3B%3Cbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272628%22%3E%3Ci%3EDDB_G0272628%3C%2Fi%3E%3C%2Fa%3E
chr2	3753105	3754460	-	DDB_G0274087	DDB_G0274087	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272873%22%3EDDB_G0272873%3C%2Fa%3E
chr2	3755009	3755643	-	DDB_G0274089	DDB_G0274089	there is a second copy of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0272793%22%3EDDB_G0272793%3C%2Fa%3E
chr2	3758069	3759460	+	DDB_G0274091	DDB_G0274091	NA
chr2	3759990	3761568	+	DDB_G0274093	adrm1-2	interacts with the phg2 kinase%3B pathway plays a role in the transition from growth to differentiation%3B%3C%2Fbr%3E there is a second copy of this gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272624%22%3E%3Ci%3Eadrm1-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3761741	3763698	-	DDB_G0295699	rsc11-2	conserved protein of unknown function%3B there is a second copy of this gene%2C  %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272791%22%3E%3Ci%3Ersc11-1%3C%2Fi%3E%3C%2Fa%3E
chr2	3765352	3765667	-	DDB_G0274097	sigN105-2	member of a large %3Ci%3EDictyostelium%3C%2Fi%3E gene family%3B there is a second copy of this gene%2C %3Ca href%3D%22%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB0238206%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273025%22%3E%3Ci%3EDDB_G0273025%3C%2Fi%3E%3C%2Fa%3E%3C%2Fb%3E
chr2	3766470	3766689	-	DDB_G0273925	DDB_G0273925_ps	putative pseudogene%3B hssA%2FB family gene
chr2	3770260	3771233	+	DDB_G0274765	DDB_G0274765	NA
chr2	3772081	3772377	-	DDB_G0274763	DDB_G0274763_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2	3773769	3774484	-	DDB_G0274377	DDB_G0274377	NA
chr2	3775956	3777072	+	DDB_G0274769	DDB_G0274769_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0282985%22%3EDDB_G0282985%3C%2Fa%3E 
chr2	3777877	3779287	-	DDB_G0274375	fba	catalyzes the reaction fructose-1%2C6-bisphosphate %3C%3D%3E dihydroxy-acetone-phosphate %2B D-glyceraldehyde-3-phosphate%3B expressed in pstAB cells and in upper cup during culmination
chr2	3780331	3780814	-	DDB_G0274759	DDB_G0274759_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0293992%22%3EDDB_G0293992%3C%2Fa%3E
chr2	3781238	3782033	-	DDB_G0274757	DDB_G0274757	NA
chr2	3782580	3786646	+	DDB_G0274373	gtr1	distant relative of CAZy family GT4%3B contains a central glycosyltransferase domain and a C-terminal sulfotransferase domain
chr2	3786786	3788150	-	DDB_G0274371	mpheS	catalyzes the reaction ATP %2B L-phenylalanine %2B tRNAPhe %3D AMP %2B diphosphate %2B L-phenylalanyl-tRNAPhe
chr2	3788355	3789149	+	DDB_G0274771	DDB_G0274771	NA
chr2	3790253	3791311	+	DDB_G0274369	DDB_G0274369	NA
chr2	3791790	3794477	-	DDB_G0274367	DDB_G0274367	ortholog of mammalian CWF19l2 and S.pombe cwf19
chr2	3794897	3796212	+	DDB_G0274365	DDB_G0274365	NA
chr2	3796506	3798173	-	DDB_G0274363	DDB_G0274363	NA
chr2	3799719	3801901	+	DDB_G0274773	fslH	similar to the G-protein coupled receptors%3B contains 7 putative transmembrane domains and a putative signal peptide
chr2	3801963	3803636	-	DDB_G0274361	prpf38a	contains a conserved PRP38 domain involved in mRNA splicing in yeast
chr2	3804521	3806675	+	DDB_G0274775	phdI	highly similar to Entamoeba histolytica PH domain proteins
chr2	3807703	3808566	+	DDB_G0274597	ctnA	component of the counting factor complex%2C which includes CF60%2C CF50%2C CF45-1%2C and CtnA (countin)
chr2	3809416	3815083	+	DDB_G0274777	DDB_G0274777	similar to Dna2%2C a DNA replication factor required for Okazaki fragment processing and  involved in DNA repair pathways
chr2	3815183	3815868	-	DDB_G0274359	cbpK	putative Ca2%2B-binding protein with 4 putative EF-hands%3B belongs to the frequenins%2C a family of myristoyl-switch calcium-binding proteins
chr2	3816301	3816995	-	DDB_G0274357	DDB_G0274357	contains two EF hands%3B very similar to %3Ci%3EDictyostelium cbpK%3C%2Fi%3E and cbpJ%3C%2Fi%3E%3B %3Ci%3Ebelongs to the frequenins%2C a family of myristoyl-switch calcium-binding proteins
chr2	3817435	3818020	-	DDB_G0274355	DDB_G0274355	NA
chr2	3818302	3818844	+	DDB_G0274779	DDB_G0274779	contains a predicted signal peptide%3B similar to D. purpureum protein
chr2	3820360	3821541	-	DDB_G0274353	DDB_G0274353	NA
chr2	3823148	3824719	+	DDB_G0274595	catA	catalyzes the reaction 2H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E %2B catalase %3D%3E 2H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E%3B expressed throughout development%3B  expression restricted to prestalk cells during post-aggregation%3Cbr%2F%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse the acrA gene encoding the late development adenylate cyclase ACR with the genetic locus acrA corresponding to the catA catalase that confers resistance to acriflavin (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Freference%2Freference.pl?refNo%3D8323%22%3EGarcia et al 2002%3C%2Fa%3E)
chr2	3825256	3826396	+	DDB_G0274781	DDB_G0274781	contains three EF hands%3B similar to mammalian neuron specific calcium-binding protein hippocalcin%3B belongs to the frequenins%2C a family of myristoyl-switch calcium-binding proteins
chr2	3826769	3830106	+	DDB_G0274785	DDB_G0274785	similar to the %3Ci%3EH. sapiens%3C%2Fi%3E TATA element modulatory factor (TMF1)%2C which binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein TBP
chr2	3830152	3831720	-	DDB_G0274351	DDB_G0274351	NA
chr2	3832237	3832973	-	DDB_G0274787	DDB_G0274787	NA
chr2	3833248	3835236	-	DDB_G0274349	DDB_G0274349	NA
chr2	3836054	3838168	-	DDB_G0274347	DDB_G0274347	NA
chr2	3839384	3840916	+	DDB_G0274755	gpt7	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr2	3841237	3847770	+	DDB_G0274789	DDB_G0274789	NA
chr2	3848103	3853768	-	DDB_G0274753	DDB_G0274753_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	3853359	3853431	-	DDB_G0294985	tRNA-Gln-UUG-10	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr2	3853864	3854650	-	DDB_G0274791	commd5	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr2	3855208	3856917	-	DDB_G0274793	DDB_G0274793	NA
chr2	3857138	3861389	-	DDB_G0274795	DDB_G0274795	very similar to mammalian USP48%3B ubiquitin-specific protease catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences and removes ubiquitin from larger groups
chr2	3862026	3864431	+	DDB_G0274593	dst1	putative protein serine%2Fthreonine kinase%3B similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B stress-responsive kinase
chr2	3864574	3865377	-	DDB_G0274591	dolpp1	catalyzes the reaction dolichyl diphosphate %2B H%3Csub%3E2%3C%2Fsub%3EO %3D dolichyl phosphate %2B phosphate%3B contains 4 putative transmembrane domains
chr2	3865902	3866270	+	DDB_G0274589	cofF	similar to cofilins%3B contains an actin-binding%2C cofilin%2Ftropomyosin type domain
chr2	3866512	3868750	+	DDB_G0274587	nup62	ortholog of the 62 kDa nucleoporin%2C an essential component of the nuclear pore complex
chr2	3869123	3870494	+	DDB_G0274585	DDB_G0274585	similar to %3Ci%3EA. thaliana%3C%2Fi%3E short chain specific acyl-Coa oxidase ACX4%2C which catalyzes the first step of peroxisomal fatty acid beta-oxidation
chr2	3870555	3870830	-	DDB_G0274583	DDB_G0274583	NA
chr2	3871056	3872872	+	DDB_G0274581	DDB_G0274581	weakly similar to human probable transcription factor SMAP (SwissProt Q15355)
chr2	3872948	3877884	-	DDB_G0274121	abcA4	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr2	3878722	3880037	+	DDB_G0274579	pitB	NA
chr2	3880324	3881047	-	DDB_G0274329	DDB_G0274329	peptidyl-prolyl cis-trans isomerase (PPIase) is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr2	3881369	3886140	-	DDB_G0274797	aqr	ortholog of the mammalian aquarius (AQR) protein%2C an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis
chr2	3887023	3888186	+	DDB_G0274331	DDB_G0274331	NA
chr2	3888367	3888791	-	DDB_G0274333	DDB_G0274333	NA
chr2	3889250	3890260	-	DDB_G0274335	DDB_G0274335	NA
chr2	3891057	3892812	+	DDB_G0274337	DDB_G0274337	NA
chr2	3892978	3896936	-	DDB_G0274577	DG1124	shares a short region of similarity with H. sapiens DBC protein (deleted in breast cancer)
chr2	3898333	3899689	+	DDB_G0274339	DDB_G0274339	belongs to the thiolase family%3B similar to human ACAA1
chr2	3900148	3902832	-	DDB_G0274341	DDB_G0274341	NA
chr2	3904161	3906570	-	DDB_G0274799	cpsf3	ortholog of the human CPSF3 and yeast YSH1%2C the 73 kDa subunit of the cleavage and polyadenylation specificity factor (CPSF) complex required for 3%27 processing of mRNAs
chr2	3907672	3907998	+	DDB_G0274343	DDB_G0274343	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon
chr2	3908527	3909871	+	DDB_G0274345	DDB_G0274345	belongs to the band 7 proteins%2C integral membrane proteins that ares thought to regulate cation conductance%3B stomatin is an erythrocyte membrane protein%3B contains an N-terminal transmembrane domain that might be a signal sequence
chr2	3911402	3914055	-	DDB_G0274801	DDB_G0274801	NA
chr2	3914880	3916187	-	DDB_G0274751	DDB_G0274751	NA
chr2	3917072	3917692	-	DDB_G0274747	DDB_G0274747	NA
chr2	3918064	3919323	-	DDB_G0274745	DDB_G0274745	NA
chr2	3920096	3922148	+	DDB_G0274327	DDB_G0274327	ortholog of S. cerevisiae SPN1 (ISW1)%2C a probable transcriptional elongation factor
chr2	3922420	3925024	-	DDB_G0274743	pisA	ortholog of human PIAS1 (protein inhibitor of activated STAT)%2C an E3 SUMO-protein ligase that acts as a transcriptional coregulation in various mammalian cellular pathways%2C including the STAT pathway%2C the p53 pathway and the steroid hormone signaling pathway
chr2	3925969	3927744	-	DDB_G0274741	gnt15	CAZy family GT49%3B similar to vertebrate acetylglucosaminyltransferase-like protein (LARGE)%3B essential for development
chr2	3928531	3933047	-	DDB_G0274803	trappc9	conserved trafficking protein particle (TRAPP) complex subunit%3B mutations in the human TRAPP9 cause mental retardation%2C autosomal recessive 13
chr2	3933601	3935563	+	DDB_G0295827	DDB_G0295827	NA
chr2	3936489	3938415	+	DDB_G0274805	ibrA	similar to the IRSp53 and MIM families of I-BAR domains%3B co-localizes with clathrin spots and seems to be involved in clathrin-mediated endocytosis%3B co-localizes with contractile vacuole system and is involved in osmoregulation%2C phagocytosis%2C and cytokinesis%3B does localize to filopodia tips but is not involved in filopodium formation
chr2	3938972	3939599	-	DDB_G0274311	DDB_G0274311	similar to the mammalian NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13)%3B contains one predicted transmembrane domain
chr2	3939967	3940520	-	DDB_G0274313	pex4	ortholog of peroxin 4%2C a peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis
chr2	3941346	3942811	+	DDB_G0274739	DDB_G0274739	contains 5 predicted transmembrane domains
chr2	3943086	3943974	-	DDB_G0274315	dpiA	NA
chr2	3944535	3945986	-	DDB_G0274317	DDB_G0274317	NA
chr2	3946871	3948811	-	DDB_G0274807	DDB_G0274807	NA
chr2	3949604	3951568	+	DDB_G0274809	mppA1	part of a complex that removes the transit peptide from the precursor form of proteins imported from the cytoplasm across the mitochondrial inner membrane%3B consists of an alpha and a beta (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0288777%22%3E%3Ci%3EmppB%3C%2Fi%3E%3C%2Fa%3E) subunit%3B there is another alpha subunit%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0290997%22%3E%3Ci%3EmppA2%3C%2Fi%3E%3C%2Fa%3E
chr2	3952988	3954022	+	DDB_G0274319	DDB_G0274319	NA
chr2	3954678	3956243	+	DDB_G0274321	purF	catalyzes the reaction L-glutamine %2B PRPP %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E 5-phospho-beta-D-ribosyl-amine %2B pyrophosphate %2B L-glutamate%2C the first step in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis
chr2	3956333	3957257	-	DDB_G0274323	DDB_G0274323	NA
chr2	3957548	3959667	+	DDB_G0274325	ddx52	ortholog of H. sapiens DDX52 and S. cerevisiae ROK1 (Rescuer Of Kem1)%3B ROK1 required for 18S rRNA synthesis
chr2	3960245	3963050	+	DDB_G0274575	myoK	class 1 myosin lacking the traditional tail domains common to short-tailed myosins%3B binds actin and is in complex with several other proteins%2C involved in phagocytosis%2C maintenance of cortical tension%2C and motility
chr2	3963501	3964860	+	DDB_G0274573	DDB_G0274573	contains a putative signal peptide and a C-terminal transmembrane domain
chr2	3967434	3970879	+	DDB_G0274811	argB	catalyzes the reaction ATP %2B N-acetyl-L-glutamate %3D ADP %2B N-acetyl-L-glutamate 5-phosphate
chr2	3971713	3974843	+	DDB_G0274813	DDB_G0274813	conserved protein%2C mainly among fungi and plants
chr2	3974977	3975525	-	DDB_G0274815	dlcB	dynein is a multisubunit microtubule-dependent motor enzyme that acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules
chr2	3975881	3976547	+	DDB_G0274571	mmgt	ortholog of the magnesium transporter MMGT1%2C contains a putative signal sequence and one transmembrane domain
chr2	3977236	3980011	+	DDB_G0274569	acgA	single transmembrane adenylyl cyclase expressed during and regulating spore germination
chr2	3980092	3981225	-	DDB_G0274567	mtrpS	catalyzes the reaction ATP %2B L-tryptophan %2B tRNATrp %3C%3D%3E AMP %2B diphosphate %2B L-tryptophan-tRNAThr%3B similar to bacterial tryptophan-tRNA ligases
chr2	3981595	3982101	-	DDB_G0274303	DDB_G0274303	NA
chr2	3982536	3984480	-	DDB_G0274305	DDB_G0274305	bears no similarity to any other gene in public databases
chr2	3985805	3987046	+	DDB_G0274735	DDB_G0274735	bears no significant similarity with any other protein%2C other than containing several evenly spaced cysteine residues
chr2	3987188	3988660	-	DDB_G0274307	DDB_G0274307	NA
chr2	3989396	3992659	-	DDB_G0274819	DDB_G0274819	NA
chr2	3992986	3995550	-	DDB_G0274821	DDB_G0274821	does not contain the consensus sequences required for kinase function
chr2	3996443	3997499	-	DDB_G0274309	DDB_G0274309	expressed in prespore cells
chr2	3998159	3998902	-	DDB_G0274565	erh	ortholog of the conserved ERH protein (Enhancer of Rudimentary Homolog) that might play a role in the cell cycle
chr2	3999704	4001665	+	DDB_G0274127	DB10	NA
chr2	4001854	4003873	-	DDB_G0274823	DDB_G0274823	NA
chr2	4004221	4006226	-	DDB_G0274267	DDB_G0274267	contains a galactose oxidase%2Fkelch beta-propeller domain%3B galactose oxidase catalyzes the oxidation of the C6 hydroxyl group in D-galactose%3B kelch may have a cytoskeletal function%3B similar to D. purpureum gene
chr2	4007291	4009014	-	DDB_G0274269	DDB_G0274269	highly similar to H. sapiens and S. cerevisiae HAT1%2C a subunit of the HAT1%2FHAT2 histone acetyltransferase complex
chr2	4009424	4009771	-	DDB_G0274271	DDB_G0274271	NA
chr2	4010059	4011285	-	DDB_G0274273	DDB_G0274273	NA
chr2	4012481	4022919	-	DDB_G0274275	DDB_G0274275	NA
chr2	4024908	4028022	+	DDB_G0274607	gefM	promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form%3B required for adenylate cyclase activation and chemotaxis
chr2	4029040	4030737	+	DDB_G0274731	DDB_G0274731	conserved in Dictyostelium%3B contains 7 FNIP repeat regions
chr2	4031010	4034366	+	DDB_G0274277	DDB_G0274277	NA
chr2	4034427	4037276	-	DDB_G0274825	DDB_G0274825	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D
chr2	4037996	4039471	+	DDB_G0274279	tssc1	ortholog of H. sapiens TSSC1
chr2	4039593	4042522	-	DDB_G0274827	DDB_G0274827	similar to H. sapiens USP42
chr2	4043724	4044426	+	DDB_G0274281	ppiH	highly similar to human PPIH%2C a snRNP-associated protein which interacts with PRP4
chr2	4044553	4045943	-	DDB_G0274283	DDB_G0274283	NA
chr2	4047769	4048899	-	DDB_G0274285	act20	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr2	4049951	4051858	+	DDB_G0274287	fslC	similar to the G-protein coupled receptors%3B contains 7 putative transmembrane domains
chr2	4052062	4053192	-	DDB_G0274561	act21	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)  
chr2	4053689	4054819	+	DDB_G0274727	act19	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr2	4055916	4057046	+	DDB_G0274135	act6	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)  
chr2	4057449	4058896	-	DDB_G0274829	rmd5	ortholog of the conserved RMD5%2C which in yeast has has an E3-like ubiquitin ligase activity
chr2	4059892	4061463	+	DDB_G0274289	DDB_G0274289	NA
chr2	4061568	4062080	-	DDB_G0274831	DDB_G0274831	similar to bacteriophage T4 lysozyme (EC 3.2.1.17)
chr2	4062693	4063205	-	DDB_G0274291	DDB_G0274291	similar to bacteriophage T4 lysozyme (EC 3.2.1.17)
chr2	4063639	4064346	-	DDB_G0274725	DDB_G0274725	NA
chr2	4065363	4066961	+	DDB_G0274293	DDB_G0274293	NA
chr2	4068268	4069914	-	DDB_G0274295	DDB_G0274295	The RWP-RK domain is named after a conserved motif at its C-terminus%3B found in %3Ci%3EChlamydomonas%3C%2Fi%3E%2C plant proteins involved in nitrogen-controlled development%2C and in %3Ci%3EDictyostelium%3C%2Fi%3E
chr2	4072005	4073042	-	DDB_G0274833	mapksp1	ortholog of human MAPKSP1 which is an adaptor protein required for MAPK signaling and ERK1%2F2 activation
chr2	4075525	4080816	+	DDB_G0274605	gefR	guanine nucleotide exchange factor required for maximal activation of RasG%3Cbr%2F%3E %3Cb%3ENomenclature conflict%3C%2Fb%3E: gefR was originally named RasGEFA in the Insall lab%2C as it was the second RasGEF (after aimless) to be identified there.  When aimless (aleA) was renamed gefA to make the nomenclature consistent and systematic%2C  RasGEFA was renamed gefR.  All published literature refers to the GEFs correctly%2C but  Kae et al. (2007) and other documents occasionally refer to the older name.
chr2	4081769	4083274	+	DDB_G0274297	fut3	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr2	4084607	4084652	-	DDB_G0295507	r42	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr2	4084929	4084972	-	DDB_G0295509	r43	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr2	4085599	4086167	+	DDB_G0274299	DDB_G0274299	expressed in pstAB cells
chr2	4086866	4087964	-	DDB_G0274723	DDB_G0274723	NA
chr2	4088247	4088869	+	DDB_G0274835	DDB_G0274835	NA
chr2	4089271	4091779	+	DDB_G0274105	glgB	transfers a segment of a 1%2C4-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain
chr2	4091903	4097175	-	DDB_G0274103	ggtA	CAZy family GT24%3B catalyzes N-linked glucosylation%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FGgtA%22%3Ecommunity annotation%3C%2Fa%3E
chr2	4097612	4100491	+	DDB_G0274301	DDB_G0274301	NA
chr2	4101568	4102902	-	DDB_G0274721	DDB_G0274721_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	4103316	4106209	+	DDB_G0274837	DDB_G0274837_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	4103357	4103439	+	DDB_G0294849	tRNA-Leu-UAA-2	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	4106680	4107279	-	DDB_G0274839	DDB_G0274839_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4108028	4108669	-	DDB_G0274719	DDB_G0274719_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4108767	4109042	-	DDB_G0274717	DDB_G0274717_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4109270	4109340	-	DDB_G0294983	tRNA-Gly-GCC-2	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr2	4109588	4110364	+	DDB_G0274253	DDB_G0274253	NA
chr2	4110567	4112012	-	DDB_G0274715	DDB_G0274715	contains 2 putative transmembrane domains
chr2	4112099	4117807	+	DDB_G0274841	fncM	ortholog of Fanconi anaemia complementation group M protein%2C involved DNA cross-link repair%3B null mutant is sensitive to DNA damaging agents   %3Cbr%2F%3E%3Cbr%2F%3E  mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A%2C B%2C C%2C E%2C F%2C G%2C L and M%3B  the FA complex interacts with ube2t%2C a E2 ubiquitin-conjugating enzyme%2C to monoubiquitinate  FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the  FANCJ helicase as well as FANCN and FANCD1%3B in human%2C mutations in this gene cause Fanconi anaemia%2C an autosomal recessive disorder affecting all bone marrow elements%3B Dictyostelium has orthologs for %3Ca href%3D%22%2Fgene%2FDDB_G0268216%22%3EFANCD2%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0279669%22%3EFANCE%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0292744%22%3EFANCL%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0293476%22%3EFANCI%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0286621%22%3EFANCJ%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274841%22%3EFANCM%3C%2Fa%3E and   %3Ca href%3D%22%2Fgene%2FDDB_G0291199%22%3EUbe2t%3C%2Fa%3E.  
chr2	4120597	4124065	+	DDB_G0274255	DDB_G0274255	NA
chr2	4124527	4125207	-	DDB_G0274257	fhit	ortholog of human FHIT which is a possible tumor suppressor for specific tissues%3B numerous tumor types are associated with aberrant forms of human FHIT protein
chr2	4126091	4129676	+	DDB_G0274259	DDB_G0274259	NA
chr2	4129800	4131107	-	DDB_G0274261	DDB_G0274261	NA
chr2	4131815	4132808	+	DDB_G0274263	DDB_G0274263	catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione
chr2	4133180	4135914	-	DDB_G0302543	DDB_G0302543	NA
chr2	4137196	4138932	+	DDB_G0274713	DDB_G0274713	catalyzes the reaction S-adenosyl-L-methionine %3C%3D%3E 1-aminocyclopropane-1-carboxylate %2B methylthioadenosine
chr2	4139227	4141170	-	DDB_G0274265	DDB_G0274265	NA
chr2	4141983	4142464	-	DDB_G0274711	DDB_G0274711	NA
chr2	4143013	4143496	-	DDB_G0274709	DDB_G0274709	NA
chr2	4144032	4144859	-	DDB_G0274559	udkB	catalyzes the reaction ATP %2B uridine %3C%3D%3E ADP %2B UMP
chr2	4146331	4149291	+	DDB_G0274247	fam91	conserved protein 
chr2	4151111	4152471	+	DDB_G0274707	gpt5	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr2	4152834	4154075	+	DDB_G0274251	DDB_G0274251	NA
chr2	4154286	4154785	-	DDB_G0274249	DDB_G0274249	NA
chr2	4155932	4156922	+	DDB_G0274705	DDB_G0274705	catalyzes the reaction RX %2B glutathione %3D HX %2B R-S-glutathione
chr2	4156981	4162118	-	DDB_G0274119	abcA5	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr2	4163363	4164152	-	DDB_G0274557	DDB_G0274557	NA
chr2	4164827	4165996	+	DDB_G0274555	prp18	conserved splicing factor participating in the second catalytic step of splicing
chr2	4167400	4169395	+	DDB_G0274553	vatH	ortholog of the H subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the H subunit is part of the V1 subunit
chr2	4169606	4173217	-	DDB_G0274845	DDB_G0274845	NA
chr2	4174381	4176090	+	DDB_G0274109	paxB	paxillin homolog containing 4 highly conserved LIM domains and 4 paxillin LD domains%3B involved in adhesion%2C culmination and cell sorting%2C slug formation and migration%2C and endocytosis
chr2	4177568	4183467	+	DDB_G0274847	DDB_G0274847	NA
chr2	4184904	4187897	+	DDB_G0274703	DDB_G0274703	contains 3 predicted coiled-coil regions
chr2	4189206	4189483	+	DDB_G0274849	DDB_G0274849	NA
chr2	4190323	4192629	+	DDB_G0274851	DDB_G0274851	NA
chr2	4193351	4194293	-	DDB_G0274551	rcdBB	NA
chr2	4195122	4195749	-	DDB_G0274549	DDB_G0274549	contains a central%2C single transmembrane domain
chr2	4197500	4199299	+	DDB_G0274547	DDB_G0274547	NA
chr2	4200277	4201101	+	DDB_G0274701	DDB_G0274701	NA
chr2	4201191	4201628	-	DDB_G0274699	wfdc	contains a putative N-terminal signal sequence%3B secreted protein
chr2	4202893	4204989	-	DDB_G0274545	thrS2	catalyzes the reaction ATP %2B L-threonine %2B tRNAThr %3D AMP %2B diphosphate %2B L-threonyl-tRNAThr
chr2	4205325	4207208	+	DDB_G0274697	taf12	subunit of TFIID and SAGA complexes%2C involved in RNA polymerase II transcription initiation and in chromatin modification
chr2	4207853	4209433	+	DDB_G0274695	slp	ortholog of human CD2 binding protein%2Fproline-serine-threonine phosphatase-interacting protein 1
chr2	4210021	4212112	+	DDB_G0274853	DDB_G0274853	NA
chr2	4213176	4214537	+	DDB_G0274859	prdx4	expressed in prespore cells%3B ortholog of peroxiredoxin 4%3B catalyzes the reaction reduced thioredoxin %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E oxidized thioredoxin %2B H%3Csub%3E2%3C%2Fsub%3EO
chr2	4215708	4216412	-	DDB_G0274543	DDB_G0274543	NA
chr2	4216447	4217739	-	DDB_G0274861	DDB_G0274861	NA
chr2	4218420	4219304	+	DDB_G0274245	DDB_G0274245	NA
chr2	4221285	4224896	+	DDB_G0274243	gacF	NA
chr2	4225429	4226889	+	DDB_G0274863	DDB_G0274863	contains a predicted signal peptide and 6 putative transmembrane domains
chr2	4227111	4230916	-	DDB_G0274241	bre1	very similar in the C-terminal RING Zn finger domain%3B belongs to the BRE1 family
chr2	4232211	4232806	-	DDB_G0274239	eIF1	EIF1%2FSUI1 ortholog%2C the eukaryotic initiation factor 1 involved in recognition of the initiator codon
chr2	4233488	4235149	-	DDB_G0274693	DDB_G0274693	contains a BRCT domain (C-terminal domain of a breast cancer susceptibility protein)%2C which is often found in proteins involved in cell cycle checkpoint
chr2	4235469	4237927	-	DDB_G0274541	DDB_G0274541	NA
chr2	4238537	4241202	-	DDB_G0274691	DDB_G0274691	NA
chr2	4245076	4246194	-	DDB_G0274689	DDB_G0274689	NA
chr2	4246508	4249696	+	DDB_G0274687	DDB_G0274687	NA
chr2	4249771	4251255	-	DDB_G0274685	DDB_G0274685	NA
chr2	4252777	4253466	+	DDB_G0274865	DDB_G0274865	NA
chr2	4254270	4255028	+	DDB_G0274539	DDB_G0274539	similar to D. purpureum protein%3B there is a similar second gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269082%22%3E%3Ci%3EDDB_G0269082%3C%2Fi%3E%3C%2Fa%3E
chr2	4256257	4257035	+	DDB_G0274867	DDB_G0274867	NA
chr2	4257363	4261957	-	DDB_G0274537	DDB_G0274537	contains a sac phosphatase domain%2C similar to D. discoideum sac1%3B similar to D. purpureum protein
chr2	4263139	4264506	+	DDB_G0274535	DDB_G0274535	similar to a D. purpureum protein
chr2	4264802	4266628	-	DDB_G0274533	DDB_G0274533	NA
chr2	4268033	4272446	-	DDB_G0274529	cfr_ps3	putative pseudogene%3B highly similar to cfr (Cell Fusion Related) genes (cell surface glycoprotein GP138)
chr2	4273673	4275158	+	DDB_G0274871	hgsB	homolog of human HMGCS1%3B catalyzes the reaction acetyl-CoA %2B H2O %2B acetoacetyl-CoA %3D (S)-3-hydroxy-3-methylglutaryl-CoA %2B CoA%3B contains a predicted peroxisomal targeting signal
chr2	4275808	4277314	-	DDB_G0274527	DDB_G0274527	very similar to bacterial and protozoan cobalamin synthesis proteins
chr2	4278392	4280036	+	DDB_G0274525	rad9	similar to S. pombe Rad9%2C a component of a heterotrimeric clamp (the 9-1-1 complex) that recognizes damaged DNA and initiates signal transduction for repair
chr2	4280121	4283887	-	DDB_G0274603	kif9	plays a role in connecting the centrosome with the nucleus
chr2	4285182	4285557	+	DDB_G0274125	gpgA	NA
chr2	4286028	4288952	-	DDB_G0274523	DDB_G0274523	NA
chr2	4289980	4291123	-	DDB_G0274521	rrs1	ortholog of S. cerevisiae RRS1%2C an essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis%3B mouse homolog shows altered expression in Huntington%27s disease model mice
chr2	4292502	4296245	+	DDB_G0274519	napA	NA
chr2	4297070	4298246	+	DDB_G0274517	osbE	NA
chr2	4298827	4300600	+	DDB_G0274681	DDB_G0274681	NA
chr2	4301386	4303530	+	DDB_G0274679	DDB_G0274679	NA
chr2	4304114	4306109	+	DDB_G0274677	DDB_G0274677	conserved in Dictyostelium%3B weak similarity to putative cell number regulator%3B contains a predicted signal anchor sequence
chr2	4306433	4307943	+	DDB_G0274515	DDB_G0274515	NA
chr2	4308167	4309355	-	DDB_G0274873	pex19	putative ortholog of peroxin 19%2C required for peroxisome biogenesis%3B mutations in human homolog cause peroxisomal disorders
chr2	4309796	4311466	-	DDB_G0274513	DDB_G0274513	NA
chr2	4311743	4317597	-	DDB_G0274875	rnf160	putative ortholog of mammalian RNF160
chr2	4317924	4320460	-	DDB_G0274877	DDB_G0274877	NA
chr2	4320828	4322705	-	DDB_G0274107	sfbA	NA
chr2	4324545	4330064	+	DDB_G0274879	DDB_G0274879	NA
chr2	4330307	4332238	+	DDB_G0274511	DDB_G0274511	ortholog of vitellogenic carboxypeptidase%2C a conserved serine carboxypeptidase expressed in mosquito ovaries%3B contains a predicted signal peptide
chr2	4332352	4333848	-	DDB_G0274509	DDB_G0274509	NA
chr2	4334242	4335594	-	DDB_G0274881	DDB_G0274881	NA
chr2	4336031	4337566	-	DDB_G0274883	DDB_G0274883	NA
chr2	4339292	4340830	-	DDB_G0274675	DDB_G0274675	NA
chr2	4342175	4344320	-	DDB_G0274885	cdc73	component of the conserved Paf1 complex%2C a multifunctional complex%2C involved in histone methylation and plays a role in RNA elongation and processing%3B defects in human CDC73 cause hyperparathyroidism-jaw tumor syndrome (HPT-JT)%2C parathyroid carcinoma%2C and hyperparathyroidism (FIHP)
chr2	4345083	4346462	+	DDB_G0274887	DDB_G0274887	NA
chr2	4347895	4348119	+	DDB_G0274507	DDB_G0274507	NA
chr2	4349111	4352710	+	DDB_G0274889	gxcX	NA
chr2	4353208	4354713	-	DDB_G0274673	DDB_G0274673_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4355252	4356016	+	DDB_G0274671	DDB_G0274671_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4356024	4356094	-	DDB_G0294981	tRNA-Gly-GCC-1	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr2	4356640	4358340	-	DDB_G0274891	DDB_G0274891	contains one transmembrane domain
chr2	4359088	4362010	-	DDB_G0274893	DDB_G0274893	conserved protein
chr2	4363008	4363964	-	DDB_G0274895	DDB_G0274895	NA
chr2	4364366	4367779	-	DDB_G0274897	DDB_G0274897	contains one coiled-coil domain
chr2	4368652	4373547	-	DDB_G0274899	DDB_G0274899	NA
chr2	4375605	4376528	+	DDB_G0274379	DDB_G0274379	NA
chr2	4376727	4378417	-	DDB_G0274505	DDB_G0274505	NA
chr2	4379150	4382891	-	DDB_G0274503	plk	putative protein serine%2Fthreonine kinase%3B similar to yeast CDC5%2C Drosophila polo%2C and mammalian PLK%2C which play a role in mitosis and localize to the centrosomes
chr2	4384213	4385523	+	DDB_G0274501	mcfY	belongs to the substrate carrier proteins that are involved in energy transfer%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr2	4386087	4387530	+	DDB_G0274499	DDB_G0274499	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity%3B contains a predicted signal peptide
chr2	4387839	4390473	-	DDB_G0274495	DDB_G0274495	contains one HTTM (horizontally transferred transmembrane) domain%3B contains 5 transmembrane domains
chr2	4391451	4392827	-	DDB_G0274901	DDB_G0274901	NA
chr2	4393027	4393815	-	DDB_G0274903	DDB_G0274903	NA
chr2	4394654	4395523	-	DDB_G0274905	DDB_G0274905	NA
chr2	4395991	4396991	-	DDB_G0274669	DDB_G0274669	NA
chr2	4398044	4399181	-	DDB_G0274665	DDB_G0274665_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271548%22%3EDDB_G0271548%3C%2Fa%3E 
chr2	4399881	4399962	+	DDB_G0294851	tRNA-Ser-AGA-2	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr2	4400712	4404415	-	DDB_G0274493	lig1	ATP-dependent DNA ligase%3B required for the ligation of Okazaki fragments during lagging-strand DNA synthesis
chr2	4404875	4405433	-	DDB_G0274491	DDB_G0274491	similar to human L antigen family member 3 (LAGE3)%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0274491 codes for a small protein with significant similarities to %22L antigen%22 and pcc1. Pcc1 is a gene identified in yeast%2C which is not essential%3B however%2C mutant cells grow very slowly. In conditional pcc1 mutants at the restrictive temperature there is an increase of cells with G1 DNA content and a decrease of S-phase cells%2C suggesting that the pcc1 product can be rate limiting for the G1%2FS transition. There are also suggestions that the activity may be important in mitotic exit [Kisseleva-Romanova%2C EMBO Journal 25%2C 3576-3585 (2006)]. A human homologue of Pcc1 is the Cancer-Testis Antigen 1%2C also known as L antigen or CTAG1%2FNY-ESO1 is overexpressed in a wide variety of cancers [see Scanlan et al%2C Immunological Reviews 188%2C 22-32 (2002)]. This suggests that in metazoans%2C as in yeast%2C the activity of this gene is important in cell cycle progression.%3Cbr%3E DDB_G0274491 is fourfold overexpressed (p%3C0.01) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation. Most genes associated with cell cycle progression are overexpressed in this strain. This suggests that an activity similar to Pcc1%2FCancer-Testis Antigen 1 may be important in Dictyostelium cell cycle progression%2C and that this aspect of cell cycle regulation is thus conserved in Dicty. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0274491%22%3E There is more information on the wiki page%3C%2Fa%3E
chr2	4405595	4406197	-	DDB_G0274489	DDB_G0274489	NA
chr2	4406975	4408642	+	DDB_G0274487	DDB_G0274487	NA
chr2	4408799	4410262	-	DDB_G0274663	DDB_G0274663	similar to human PRSS16 (thymus-specific serine protease)%3B contains a putative signal peptide
chr2	4411951	4412526	+	DDB_G0274661	DDB_G0274661	expressed in prespore cells
chr2	4412777	4416227	+	DDB_G0274907	DDB_G0274907	NA
chr2	4416444	4417091	-	DDB_G0274485	DDB_G0274485	NA
chr2	4418543	4419673	+	DDB_G0274137	act14	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr2	4419877	4420908	-	DDB_G0274909	DDB_G0274909	NA
chr2	4421760	4422920	-	DDB_G0274911	DDB_G0274911_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0285989%22%3EDDB_G0285989%3C%2Fa%3E 
chr2	4423293	4428420	-	DDB_G0274483	DDB_G0274483	NA
chr2	4429085	4430625	-	DDB_G0274659	DDB_G0274659	NA
chr2	4432128	4434435	+	DDB_G0274115	abcG12	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr2	4435257	4437528	+	DDB_G0274117	abcG8	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr2	4437706	4440971	-	DDB_G0274481	DDB_G0274481	similar to mammalian XPR1%2C which may confer susceptibility to infection with murine leukaemia viruses%3B also similar to yeast SYG1%2C a G-protein associated signal transduction protein%2C and plant PHO1%2C that may be involved in phosphate transport 
chr2	4442899	4448685	-	DDB_G0274915	DDB_G0274915	NA
chr2	4449564	4450295	-	DDB_G0274479	DDB_G0274479	NA
chr2	4450801	4451136	-	DDB_G0274477	DDB_G0274477	NA
chr2	4451947	4453161	-	DDB_G0274475	DDB_G0274475	NA
chr2	4453801	4454676	+	DDB_G0274657	DDB_G0274657	related to glutaredoxin%2C which functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides
chr2	4455464	4456594	+	DDB_G0274601	act9	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)  
chr2	4457216	4475690	-	DDB_G0274917	vps13B	similar to S. cerevisiae VPS13%2C involved in vacuolar protein sorting and protein-Golgi retention
chr2	4476400	4478843	+	DDB_G0274473	DDB_G0274473	NA
chr2	4479756	4480658	+	DDB_G0274655	DDB_G0274655	NA
chr2	4481626	4482490	+	DDB_G0274471	tpiA	catalyzes the reaction D-glyceraldehyde 3-phosphate %3C%3D%3E glycerone phosphate%3B defects in human TPI1 are the cause of triosephosphate isomerase deficiency%2C severe clinical disorder of glycolysis
chr2	4482749	4483298	-	DDB_G0274469	DDB_G0274469	NA
chr2	4484019	4487468	-	DDB_G0274919	DDB_G0274919	NA
chr2	4488656	4489805	-	DDB_G0274921	DDB_G0274921	NA
chr2	4490494	4491339	+	DDB_G0274467	DDB_G0274467	NA
chr2	4491792	4493969	+	DDB_G0274653	DDB_G0274653	NA
chr2	4494014	4494496	-	DDB_G0274465	DDB_G0274465	conserved hypothetical protein%3B contains an N-terminal hydrophobic region
chr2	4495093	4496223	-	DDB_G0274599	act13	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr2	4496721	4498102	-	DDB_G0274651	gpt4	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr2	4499141	4504150	+	DDB_G0274649	DDB_G0274649	NA
chr2	4505147	4507593	-	DDB_G0274463	mybJ	contains one Myb DNA-binding domain
chr2	4508759	4509952	+	DDB_G0274461	DDB_G0274461	NA
chr2	4510635	4513139	+	DDB_G0274111	pfkA	catalyzes the reaction ATP %2B D-fructose 6-phosphate %3C%3D%3E ADP %2B D-fructose 1%2C6-bisphosphate%3B the %3Ci%3EDictyostelium%3C%2Fi%3E PFK has been found to be a non-allosteric enzyme that binds to tubulin and inhibits tubulin polymerization
chr2	4513889	4516210	+	DDB_G0274923	DDB_G0274923	NA
chr2	4516555	4516782	-	DDB_G0274647	DDB_G0274647_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr2	4517216	4518656	-	DDB_G0274645	DDB_G0274645_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr2	4518975	4521351	+	DDB_G0274925	DDB_G0274925_ps	putative pseudogene%3B fragment%2C similar to the genes %3Ca href%3D%22%2Fgene%2FDDB_G0293720%22%3EDDB_G0293720%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0293722%22%3EDDB_G0293722%3C%2Fa%3E
chr2	4523083	4523223	+	DDB_G0274459	DDB_G0274459	conserved hypothetical Dictyostelium protein%3B identical to %3Ca href%3D%22%2Fgene%2FDDB_G0277595%22%3EDDB_G0277595%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0269070%22%3EDDB_G0269070%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0294605%22%3EDDB_G0294605%3C%2Fa%3E
chr2	4523885	4524287	-	DDB_G0349834	DDB_G0349834_ps	putative pseudogene%3B fragment%2C similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0286673%22%3EDDB_G0286673%3C%2Fa%3E
chr2	4525163	4526298	-	DDB_G0274457	coq9	ortholog of the conserved COQ9%2C a protein which in %3Ci%3ES. cerevisiae%3C%2Fi%3E is required for ubiquinone (coenzyme Q) biosynthesis
chr2	4526720	4528613	-	DDB_G0274927	DDB_G0274927	NA
chr2	4531583	4532438	+	DDB_G0274643	DDB_G0274643	NA
chr2	4534415	4541848	+	DDB_G0274455	myoI	similar to the conserved MYO7A%3B unconventional myosin required in %3Ci%3EDictyostelium%3C%2Fi%3E for phagocytosis and substrate adhesion
chr2	4542146	4546869	+	DDB_G0274931	DDB_G0274931	NA
chr2	4547444	4548266	-	DDB_G0274453	DDB_G0274453_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0289133%22%3EDDB_G0289133%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0272072%22%3EDDB_G0272072%3C%2Fa%3E
chr2	4548951	4549728	+	DDB_G0274933	DDB_G0274933	NA
chr2	4555761	4557401	+	DDB_G0274935	DDB_G0274935	NA
chr2	4557935	4560218	+	DDB_G0274939	aslB	highly similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA 
chr2	4563185	4568200	+	DDB_G0274101	dokA	NA
chr2	4569510	4570958	+	DDB_G0274641	DDB_G0274641	NA
chr2	4571492	4572853	+	DDB_G0274123	pyd3	NA
chr2	4573546	4574736	+	DDB_G0274451	DDB_G0274451	NA
chr2	4574977	4576552	-	DDB_G0274449	scsB	catalyzes the reaction GTP %2B succinate %2B CoA %3D GDP %2B phosphate %2B succinyl-CoA
chr2	4577027	4578042	-	DDB_G0274447	psmG2	conserved chaperone protein%2C which promotes assembly of the 20S proteasome%3B may form a dimer with psmG1 and act in concert with psmG3%2FpsmG4
chr2	4578208	4578843	-	DDB_G0274445	arrB	NA
chr2	4579134	4579992	-	DDB_G0274443	med30	putative and poorly conserved mediator of RNA polymerase II transcription subunit 30%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr2	4580344	4581051	-	DDB_G0274099	cbpE	NA
chr2	4581583	4582705	-	DDB_G0274941	omt2	NA
chr2	4583590	4586725	-	DDB_G0274943	ranB	contains two Ran domains
chr2	4588497	4591176	+	DDB_G0274441	psiL	contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 4 Dictyostelium (CTDC) repeats and a C-terminal transmembrane domain
chr2	4591973	4593236	+	DDB_G0274945	DDB_G0274945_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr2	4593609	4595098	-	DDB_G0274113	rpl8	protein component of the large (60S) ribosomal subunit%3B ribosomal protein L8 homolog
chr2	4596108	4596426	+	DDB_G0274439	DDB_G0274439	in E. coli%2C bolA plays a role in general stress response and affects cellular morphogenesis%3B this protein is about 50 amino acids shorter on the amino terminus compared to homologs
chr2	4596611	4597975	-	DDB_G0274437	twfA	A6 family protein kinase%3B very similar to human and mouse twinfilin (A6 protein)%2C which is a tyrosine kinase and an actin monomer binding protein%3B contains two ADF domains (actin depolymerization factor%2Fcofilin-like domains)
chr2	4598646	4603284	-	DDB_G0274947	DDB_G0274947	NA
chr2	4603856	4605593	+	DDB_G0274435	DDB_G0274435	NA
chr2	4606302	4607553	+	DDB_G0274433	DDB_G0274433	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0274433 is weakly similar to SDS23 and SDS24 of budding yeast%2C which are themselves homologues of sds23 from fission yeast. The fission yeast gene interacts with the anaphase promoting complex in a manner which is not understood molecularly. The APC must be dephosphoryated by PPI for normal mitosis%2C and sds23 overexpressers bypass the requirement for PPI (Ishii et al%2C EMBO Journal 15%2C 6629-6640 (1996). Deletion of sds23 gives very slowly growing cells with multiple nuclei and extremely prolonged anaphase. In budding yeast%2C however%2C the double deletion is viable with changes mainly in the size of the vacuole. In Dicty%2C a role of DDB_G0274433 in cell cycle control is suggested by the gene%27s fivefold overexpression in a Dicty strain deficient in the Dictyostelium %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E. Most genes associated with DNA replication or mitosis are overexpressed in this strain.  (Doquang et al%2C in preparation).%3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C September 2009 %3C%2Fi%3E
chr2	4607655	4612543	-	DDB_G0274429	DDB_G0274429	NA
chr2	4613288	4618186	-	DDB_G0274427	DDB_G0274427	NA
chr2	4618827	4623023	-	DDB_G0274425	DDB_G0274425	the protein phosphatase 2C-related domain occurs in protein phosphatase 2C (PPC2) as well as in other proteins%2C such as pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase
chr2	4625298	4627388	+	DDB_G0274423	DDB_G0274423	contains 3 SH3 (Src homology 3) domains
chr2	4627713	4631312	-	DDB_G0274419	DDB_G0274419	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0274419 appears to encode a DNA polymerase with closest affinities to pol I of bacteria (the Kornberg polymerase). This is a low-processivity polymerase thought to function in DNA repair. DDB_G0274419 is only marginally (2x)overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). DNA polymerases associated with replication show overexpression factors of 5- to 14-fold in this strain%2C as as do several genes associated with replication-coupled repair%2C while most genes associated with replication-independent repair pathways show overexpression factors of 2 or less. This suggests that DDB_G0274419 acts in replication-uncoupled DNA repair. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E
chr2	4631680	4633744	-	DDB_G0274949	DDB_G0274949	NA
chr2	4634989	4635411	-	DDB_G0274951	DDB_G0274951	NA
chr2	4635539	4635676	+	DDB_G0274417	DDB_G0274417	NA
chr2	4635738	4635923	+	DDB_G0274415	DDB_G0274415	NA
chr2	4636251	4636637	-	DDB_G0274413	DDB_G0274413_ps	NA
chr2	4637236	4639295	-	DDB_G0274637	DDB_G0274637	NA
chr2	4640782	4642356	-	DDB_G0274411	DDB_G0274411_ps	putative pseudogene
chr2	4643728	4645821	-	DDB_G0274635	DDB_G0274635_ps	putative pseudogene%3B similar to a small family of genes%2C including the neighboring %3Ca href%3D%22%2Fgene%2FDDB_G0274631%22%3EDDB_G0274631%3C%2Fa%3E
chr2	4645992	4648072	-	DDB_G0274631	DDB_G0274631	NA
chr2	4648326	4651856	-	DDB_G0274409	pakF	putative protein serine%2Fthreonine kinase%3B belongs to the protein kinase PAKL subfamily%3B the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B stress-responsive kinase
chr2	4652461	4654353	-	DDB_G0274953	DDB_G0274953	NA
chr2	4656194	4657430	+	DDB_G0274955	etnkA	catalyzes the reaction ATP %2B ethanolamine %3D ADP %2B O-phosphoethanolamine
chr2	4658071	4658280	+	DDB_G0274629	DDB_G0274629	contains no functional domains and is not similar to any other protein
chr2	4659350	4659546	+	DDB_G0274957	DDB_G0274957_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0268186%22%3EDDB_G0268186%3C%2Fa%3E 
chr2	4661589	4663036	-	DDB_G0274407	DDB_G0274407	NA
chr2	4663584	4664796	-	DDB_G0274405	DDB_G0274405	NA
chr2	4665266	4667207	-	DDB_G0274627	eif3D	EIF3S7%2C and  S. pombe Moe1 ortholog%2C the eukaryotic initiation factor zeta subunit%3B in human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr2	4667606	4669305	-	DDB_G0274401	DDB_G0274401	similar to D. purpureum protein
chr2	4669717	4670400	+	DDB_G0274959	mrpl13	protein component of the mitochondrial large ribosomal subunit
chr2	4670597	4672052	-	DDB_G0274961	DDB_G0274961	NA
chr2	4672730	4676440	+	DDB_G0274963	DDB_G0274963	NA
chr2	4676573	4680775	-	DDB_G0274965	DDB_G0274965	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr2	4681340	4684368	+	DDB_G0274399	DDB_G0274399	similar to ATP-dependent RNA helicase M NAM7and to putative helicases involved in RNA maturation SEN1%3B human senataxin%2C imlicated in ataxia-ocular apraxia 2 (AOA2) and amyotrophic lateral sclerosis 4 (ALS4) also belongs to this family
chr2	4684532	4685313	-	DDB_G0274967	aplL	NA
chr2	4686286	4687900	-	DDB_G0274397	DDB_G0274397	NA
chr2	4689182	4691451	+	DDB_G0274969	DDB_G0274969	similar to mammalian lysophosphatidic acid acyltransferase zeta (1-acylglycerol-3-phosphate O-acyltransferase 6)%3B contains 3 putative transmembrane domains
chr2	4691677	4693839	-	DDB_G0274395	adcB	contains a C2 domain%2C a Ca2%2B-dependent membrane-targeting module
chr2	4696078	4696774	+	DDB_G0274237	DDB_G0274237	conserved hypothetical protein similar to H. sapiens PLAC8 (placenta-specific 8)
chr2	4698594	4698818	+	DDB_G0274235	DDB_G0274235	NA
chr2	4699494	4700859	+	DDB_G0274233	ctbsA	very similar to H. sapiens di-N-acetylchitobiase (CBTS)%2C a hydrolase involved in the degradation of asparagine-linked glycoproteins%3B contains a putative N-terminal signal sequence
chr2	4700982	4702637	-	DDB_G0274231	DDB_G0274231	NA
chr2	4703192	4710497	-	DDB_G0274229	prpf8	central component of the U4%2FU6-U5 snRNP complex%3B contains the PRO8NT%2C PROCN%2C PRO C-terminal%2C and Mov34%2FMPN%2FPAD-1 domains found in pre-mRNA splicing factors of the PRO8 family
chr2	4710807	4711396	-	DDB_G0274227	DDB_G0274227	NA
chr2	4712814	4713944	+	DDB_G0274971	DDB_G0274971	NA
chr2	4714057	4716986	-	DDB_G0274225	tgrA5	NA
chr2	4718776	4719906	-	DDB_G0274129	act12	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr2	4720551	4721540	+	DDB_G0274223	DDB_G0274223	catalyzes the reaction RX %2B glutathione %3D HX %2B R-S-glutathione
chr2	4722018	4723148	+	DDB_G0274133	act2	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)  
chr2	4723516	4724640	+	DDB_G0274131	act17	has 80%25 identity with human beta-actin (SwissProt P60709)
chr2	4725095	4727242	+	DDB_G0274973	DDB_G0274973	NA
chr2	4728670	4730554	+	DDB_G0274623	cyp519A1	NA
chr2	4730779	4736010	-	DDB_G0274975	DDB_G0274975	NA
chr2	4737491	4748865	+	DDB_G0274221	colB	NA
chr2	4749133	4752672	+	DDB_G0274219	DDB_G0274219	NA
chr2	4753411	4753637	-	DDB_G0274977	DDB_G0274977	NA
chr2	4754213	4756814	+	DDB_G0274979	DDB_G0274979	NA
chr2	4757826	4760145	-	DDB_G0274217	lsrA	ortholog of H. sapiens transcription factor 25 (TCF25)
chr2	4760642	4763155	-	DDB_G0274981	DDB_G0274981	NA
chr2	4763951	4765899	+	DDB_G0274215	DDB_G0274215	NA
chr2	4766016	4767731	-	DDB_G0274213	prpf3	component of the U4%2FU6-U5 snRNP complex%3B human PRP3 interacts with PRP4
chr2	4768104	4773452	-	DDB_G0274211	DDB_G0274211	NA
chr2	4776106	4777535	-	DDB_G0274393	DDB_G0274393	NA
chr2	4778748	4782720	-	DDB_G0274207	DDB_G0274207	similar to mammalian USP16
chr2	4783187	4784489	-	DDB_G0274209	DDB_G0274209	NA
chr2	4784888	4786574	-	DDB_G0274391	alfA	Dictyostelium enzyme that hydrolyses O- and S-glycosyl compounds with a preference for cleaving the alpha1-6-O-fucolsyl bonds in fucosylated oligosaccharides%3B secreted during development
chr2	4789311	4790403	-	DDB_G0274983	vps13D_ps2	putative pseudogene%3B fragmnent%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0286545%22%3E%3Ci%3Evps13D%3C%2Fi%3E%3C%2Fa%3E 
chr2	4790573	4792841	-	DDB_G0274195	DDB_G0274195	NA
chr2	4793181	4794748	-	DDB_G0274197	omt3	putative ortholog of METTL2A (methyltransferase like 2A)
chr2	4796097	4797482	+	DDB_G0274199	DDB_G0274199	NA
chr2	4797968	4799094	+	DDB_G0274201	DDB_G0274201	NA
chr2	4799224	4800040	-	DDB_G0274203	DDB_G0274203	NA
chr2	4800486	4801553	-	DDB_G0274205	DDB_G0274205	NA
chr2	4805683	4809360	+	DDB_G0274191	dhkC	NA
chr2	4809755	4810120	-	DDB_G0274189	ecmJ	expression is decreased in %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281381%22%3E%3Ci%3EdstA%3C%2Fi%3E%3C%2Fa%3E cells
chr2	4810741	4812557	-	DDB_G0274187	DDB_G0274187	NA
chr2	4814216	4814980	-	DDB_G0274985	DDB_G0274985_ps	putative pseudogene%3B conserved hypothetical Dictyostelium protein
chr2	4815159	4816451	-	DDB_G0274185	DDB_G0274185	contains an N-terminal oxidoreductase domain and a partial C-terminal oxidoreductase domain%3B the Gfo%2FIdh%2FMocA family proteins utilize NADP or NAD
chr2	4816957	4817847	-	DDB_G0274987	DDB_G0274987	NA
chr2	4818450	4819598	+	DDB_G0274991	DDB_G0274991	NA
chr2	4819660	4822302	-	DDB_G0274183	DDB_G0274183	NA
chr2	4824947	4827492	+	DDB_G0274993	bzpJ	NA
chr2	4831162	4832097	+	DDB_G0274181	DDB_G0274181	glycoside hydrolase family 25 (GH25) comprises enzymes with lysozyme (EC:3.2.1.17) activity%3B contains a putative N-terminal signal peptide
chr2	4832304	4833052	+	DDB_G0274179	DDB_G0274179_ps	putative pseudogene similar to it%27s neighboring gene (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274181%22%3E%3Ci%3EDDB_G0274181%3C%2Fi%3E%3C%2Fa%3E)%2C a glycoside hydrolase family 25 protein
chr2	4833721	4839855	+	DDB_G0274177	DDB_G0274177	similar to tenascin X
chr2	4841279	4842480	-	DDB_G0274175	DDB_G0274175	NA
chr2	4844842	4848156	+	DDB_G0274995	DDB_G0274995	NA
chr2	4848528	4851359	-	DDB_G0274997	DDB_G0274997	NA
chr2	4852122	4852526	-	DDB_G0274173	DDB_G0274173	NA
chr2	4853650	4855199	-	DDB_G0274171	stcC	similar to Fraser syndrome protein%2C von Willebrand factor%2C and kielin%3B expressed in pstAO cells and in upper cup during culmination
chr2	4856309	4858281	-	DDB_G0274389	pARTf	weakly similar to TNKS2
chr2	4859710	4861380	+	DDB_G0274617	DDB_G0274617	contains a single FNIP repeat
chr2	4862329	4864693	-	DDB_G0274387	dpoA	involved in regulation of inositol (1%2C4%2C5) trisphosphate levels
chr2	4865070	4865414	+	DDB_G0274169	DDB_G0274169	NA
chr2	4865578	4869561	-	DDB_G0274167	cand1	highly conserved protein%3B interacts with TATA binding protein (TBP) and with the SCF (Skp1-Cul1-F-box) ubiquitin ligase complex
chr2	4870104	4872587	-	DDB_G0274165	DDB_G0274165	NA
chr2	4873769	4874332	+	DDB_G0275001	DDB_G0275001	NA
chr2	4874703	4874834	-	DDB_G0274163	DDB_G0274163	similar to a D. purpureum protein
chr2	4876346	4877611	+	DDB_G0274385	DDB_G0274385	NA
chr2	4878022	4878948	+	DDB_G0274161	DDB_G0274161	belongs to the NADP_Rossman superfamily%3B similar to human NMRAL1%3B A. nidulans nmrA is a transcriptional regulator involved in nitrogen metabolite repression%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0274161 is similar to nmr1%2C originally identified as a Neurospora gene which binds to the transcription factor nit2%2C and prevents its binding to and activating genes required for nitrogen utilization. The human ortholog is %22NmrA-like%22%2C known as NMRAL1 or HSCARG%2C and is said to monitor the ratio of NAD to NADPH%2C acting as a redox sensor%2C which moves to the nucleus when NADPH%2FNAD drops below a threshold value [Zheng et al%2C PNAS 104%2C 8809-8814 (2007)]. DDB_G0274161 is sevenfold overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). %3Ci%3EHarry MacWilliams%2C October 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0274161%22%3E There is more information on the wiki page%3C%2Fa%3E
chr2	4879244	4880801	+	DDB_G0274159	hisS	catalyzes the reaction ATP %2B L-histidine %2B tRNAHis %3D AMP %2B diphosphate %2B L-histidyl-tRNAHis
chr2	4881010	4881177	-	DDB_G0274615	DDB_G0274615	NA
chr2	4881571	4881957	+	DDB_G0274157	DDB_G0274157	NA
chr2	4882054	4883052	-	DDB_G0274145	DDB_G0274145	NA
chr2	4883520	4883837	-	DDB_G0274147	DDB_G0274147_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0274173%22%3EDDB_G0274173%3C%2Fa%3E 
chr2	4884886	4888644	+	DDB_G0274149	DDB_G0274149	NA
chr2	4889468	4890355	+	DDB_G0274151	DDB_G0274151_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0274149%22%3EDDB_G0274149%3C%2Fa%3E
chr2	4890449	4892329	-	DDB_G0275003	DDB_G0275003	NA
chr2	4893134	4896046	-	DDB_G0274613	DDB_G0274613	kinase domain similar to mitogen-activated protein kinases%3B does not contain the consensus sequences known to be required for kinase function%3B contains a RING zinc finger domain
chr2	4896937	4897258	+	DDB_G0274611	DDB_G0274611_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0283407%22%3EDDB_G0283407%3C%2Fa%3E
chr2	4898014	4903137	+	DDB_G0275005	DDB_G0275005	putative ortholog of H. sapiens CNOT4 and S. cerevisiae MOT2%3B component of the CCR4-NOT transcription complex
chr2	4904282	4907104	+	DDB_G0274383	pdeD	contains one beta-lactamase domain and two cNMP-binding domains
chr2	4909656	4911671	+	DDB_G0274153	DDB_G0274153	protein phosphatase 2C is a serine%2Fthreonine specific protein phosphatase with broad substrate specificity and dependent on divalent cations (mainly manganese and magnesium) for its activity
chr2	4912583	4915224	+	DDB_G0274155	DDB_G0274155	NA
chr2	4916421	4917131	+	DDB_G0274143	DDB_G0274143	NA
chr2	4917455	4918802	-	DDB_G0274141	DDB_G0274141	NA
chr2	4920282	4921065	+	DDB_G0274381	vatP	ortholog of the mammalian V-type proton ATPase 16 kDa proteolipid subunit%2C the proton-conducting pore forming subunit of the vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B this protein is part of the V0 complex
chr2	4921649	4922585	+	DDB_G0274139	cycC	similar to metazoan cyclin C%3B predicted to interact with cyclin-dependent kinase %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0267442%22%3E%3Ci%3Ecdk8%3C%2Fi%3E%3C%2Fa%3E to stimulate CTD (RNA pol II C-Terminal Domain) kinase activity
chr2	4922788	4923936	-	DDB_G0274609	DDB_G0274609	similar to proteins in the Dictyostelium countin family
chr2	4924842	4925020	-	DDB_G0275229	DDB_G0275229_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0275825%22%3EDDB_G0275825%3C%2Fa%3E 
chr2	4926006	4926259	-	DDB_G0275175	DDB_G0275175	NA
chr2	4927229	4927508	-	DDB_G0275231	DDB_G0275231	NA
chr2	4928353	4928612	-	DDB_G0275233	DDB_G0275233	NA
chr2	4929416	4929704	-	DDB_G0275131	DDB_G0275131	NA
chr2	4930622	4931317	-	DDB_G0275133	DDB_G0275133	NA
chr2	4932274	4932551	-	DDB_G0275135	DDB_G0275135	NA
chr2	4934269	4934530	-	DDB_G0275137	DDB_G0275137	NA
chr2	4935740	4936447	-	DDB_G0275227	DDB_G0275227	similar to FKBP-type peptidyl-prolyl isomerase%2C which functions as a receptor for immunosuppressants in vertebrates
chr2	4936614	4937321	-	DDB_G0275225	DDB_G0275225	NA
chr2	4937448	4938189	-	DDB_G0275223	DDB_G0275223	NA
chr2	4940204	4941715	+	DDB_G0275235	captD	catalyzes the reaction CDP-choline %2B 1%2C2-diacylglycerol %3D CMP %2B a phosphatidylcholine
chr2	4941790	4943798	-	DDB_G0275237	DDB_G0275237	NA
chr2	4945321	4953278	+	DDB_G0275239	zizC	NA
chr2	4953641	4955428	+	DDB_G0275139	DDB_G0275139	NA
chr2	4955753	4957779	-	DDB_G0275141	utp5	putative ortholog of H. sapiens WDR43 and S. cerevisiae UTP4%3B component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr2	4958210	4960180	-	DDB_G0275143	DDB_G0275143	NA
chr2	4960811	4962556	-	DDB_G0275145	DDB_G0275145	contains one RING-type zinc finger and one IBR (In Between Ring fingers) domain%3B similar to S. cerevisiae RING finger protein YKR017C
chr2	4963654	4964621	-	DDB_G0275147	DDB_G0275147	NA
chr2	4965140	4967413	+	DDB_G0275149	DDB_G0275149	similar to S. cerevisiae AKR1 (palmitoyltransferase AKR1) contains 5 ankyrin repeats and 1 zinc finger DHHC domain%3B contains 6 putative transmembrane domains
chr2	4967851	4971477	-	DDB_G0275221	DDB_G0275221_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4972878	4972950	-	DDB_G0294979	tRNA-Met-CAU-9	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr2	4973434	4977723	+	DDB_G0294437	DDB_G0294437_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr2	4978458	4978973	+	DDB_G0305465	DDB_G0305465	NA
chr2	4980794	4982374	+	DDB_G0305463	DDB_G0305463_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4981255	4981328	+	DDB_G0294853	tRNA-Phe-GAA-4	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	4982711	4982863	-	DDB_G0275219	DDB_G0275219_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr2	4983192	4983365	-	DDB_G0275217	DDB_G0275217_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	4983790	4987279	-	DDB_G0275241	nek3	putative protein serine%2Fthreonine kinase%3B similar to vertebrate Nek kinases which are involved in regulation of mitosis%3B not a human Nek3 homolog
chr2	4987975	4989080	-	DDB_G0275127	DDB_G0275127	NA
chr2	4989791	4989863	-	DDB_G0294977	tRNA-Lys-UUU-8	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr2	4990595	4991138	+	DDB_G0275243	DDB_G0275243	belongs to the PLAC8 family (placenta-specific gene 8 protein)%2C a family of cysteine-rich proteins with highly divergent%2C low complexity amino terminal regions
chr2	4991620	4993493	+	DDB_G0275125	plbF	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276767%22%3E%3Ci%3EplbA%3C%2Fi%3E%3C%2Fa%3E%2C which catalyzes the hydrolysis of phosphatidylcholine to glycerophosphocholine
chr2	4995095	4995181	+	DDB_G0294855	tRNA-Trp-CCA-6	transfers a tryptophan residue to a growing polypeptide chain during protein synthesis%0A
chr2	4995682	5000416	+	DDB_G0275245	DDB_G0275245	NA
chr2	5000529	5002539	-	DDB_G0275247	DDB_G0275247	NA
chr2	5002742	5003861	-	DDB_G0275123	alyA	member of a new lysozyme class
chr2	5004280	5005342	-	DDB_G0275121	alyC	member of a new lysozyme class
chr2	5005709	5006809	-	DDB_G0275119	alyB	member of a new lysozyme class
chr2	5007231	5009306	-	DDB_G0275215	DDB_G0275215	NA
chr2	5010279	5011108	+	DDB_G0275213	DDB_G0275213	NA
chr2	5011473	5012191	+	DDB_G0275211	srp19	component of the signal recognition particle (SRP)%2C which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulum
chr2	5012674	5016758	+	DDB_G0275129	ncapGb	putative component of the condensin I complex%2C required for conversion of interphase chromatin into mitotic condensed chromosomes%3B There is another putative NCAPG gene in D. discoideum (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281419%22%3E%3Ci%3EncapGa%3C%2Fi%3E%3C%2Fa%3E)%3B two genes are also present in D. purpureum%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  ncapGb is similar to the mitotic chromosomal condensation complex condensin subunit G. The role of this gene in Dicty cell cycle control is supported by its sevenfold overexpression in a Dicty strain lacking the retinoblastoma-like gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E (Doquang et al%2C in preparation). Most genes whose products are involved in DNA replication or mitosis are overexpressed in this strain. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr2	5017002	5019830	-	DDB_G0275173	hbx2	NA
chr2	5025157	5027462	-	DDB_G0275107	DDB_G0275107	NA
chr2	5027832	5028644	-	DDB_G0275249	commd10	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr2	5029263	5030186	+	DDB_G0275251	DDB_G0275251	NA
chr2	5031311	5032265	+	DDB_G0275253	DDB_G0275253	expressed in pstO cells
chr2	5032870	5033836	+	DDB_G0275255	DDB_G0275255	expressed in pstO cells
chr2	5033896	5036134	-	DDB_G0275109	DDB_G0275109	NA
chr2	5037232	5038183	+	DDB_G0275111	DDB_G0275111	contains a predicted signal peptide%3B conserved in Dictyostelium and Polysphondylium
chr2	5038466	5041076	-	DDB_G0275257	top3	ortholog of TOP3%2C a nuclear topoisomerase responsible for relaxing single-stranded negatively-supercoiled DNA
chr2	5041441	5043297	-	DDB_G0275113	DDB_G0275113	NA
chr2	5044037	5045219	+	DDB_G0275209	cnrD	identified as a suppressor of smlA null mutant cnr4%3B contains a Cue domain%2C which may be involved in binding ubiquitin-conjugating enzymes
chr2	5045624	5045703	+	DDB_G0295511	sno10	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr2	5046259	5047451	+	DDB_G0275115	sdhC	catalyzes the reaction succinate %2B ubiquinone %3D fumarate %2B ubiquinol%3B cytochrome b560 subunit%2C contains 2 transmembrane domains
chr2	5047947	5049988	-	DDB_G0275117	DDB_G0275117	NA
chr2	5053540	5053821	+	DDB_G0275259	DDB_G0275259	similar to a D. purpureum protein%3B contains a predicted signal peptide
chr2	5054068	5055388	-	DDB_G0275177	sigI	regulated by the MADS-box transcription factor SrfA during development
chr2	5056195	5058343	-	DDB_G0275093	DDB_G0275093	similar to ubiquitin in the N-terminal region%3B contains one von Willebrand factor (vWF) type A domain
chr2	5058865	5059482	-	DDB_G0275095	mgmt	transfers methyl groups from DNA containing %3Csup%3E6%3C%2Fsup%3EO-methylguanine to a cysteine residue
chr2	5060014	5062269	+	DDB_G0275097	DDB_G0275097	NA
chr2	5062455	5063879	-	DDB_G0275099	DDB_G0275099	NA
chr2	5064677	5065523	-	DDB_G0275101	rab_ps2	putative pseudogene%3B Rab family protein
chr2	5065612	5067482	+	DDB_G0275103	DDB_G0275103	contains an N-terminal B-box zinc finger domain and 4 FNIP repeats%3B contains a predicted coiled-coil domain
chr2	5067904	5068371	+	DDB_G0275105	DDB_G0275105_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0274979%22%3EDDB_G0274979%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0278585%22%3EDDB_G0278585%3C%2Fa%3E
chr2	5068593	5070735	-	DDB_G0275261	alg8	CAZy family GT57%3B catalyzes N-linked glucosylation
chr2	5070972	5071685	+	DDB_G0275055	commd7	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr2	5072046	5073957	-	DDB_G0275171	DDB_G0275171	NA
chr2	5075841	5078052	-	DDB_G0275263	asnS1	catalyzes the reaction ATP %2B L-asparagine %2B tRNAAsn %3D AMP %2B diphosphate %2B L-asparaginyl-tRNAAsn%3B expression is repressed in low calcium
chr2	5078945	5080368	-	DDB_G0275265	etnkB	catalyzes the reaction ATP %2B ethanolamine %3D ADP %2B O-phosphoethanolamine
chr2	5081463	5083066	-	DDB_G0275205	DDB_G0275205	NA
chr2	5084018	5088290	+	DDB_G0275169	DDB_G0275169	NA
chr2	5089988	5091525	+	DDB_G0275057	DDB_G0275057	protein serine%2Fthreonine kinase%2C CAMK group%2C CAMK1 family%3B similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases
chr2	5091816	5092710	-	DDB_G0275059	DDB_G0275059	NA
chr2	5092894	5094339	+	DDB_G0275061	slc35b4	homolog of human SLC35B4%2C S. cerevisiae YEA4%3B contains 9 putative transmembrane domains
chr2	5094579	5095340	-	DDB_G0275063	DDB_G0275063	expressed in pstO cells and in pstO cells and upper cup during culmination
chr2	5096698	5101896	-	DDB_G0275065	dmpA	contains seven transmembrane domains and a possible signal peptide
chr2	5102751	5105276	+	DDB_G0275167	dstD	NA
chr2	5105558	5107490	+	DDB_G0275203	DDB_G0275203	NA
chr2	5107775	5108935	+	DDB_G0275067	DDB_G0275067	NA
chr2	5110511	5118465	+	DDB_G0275069	pks16	fatty acid synthases catalyze the formation of long-chain fatty acids from acetyl-CoA%2C malonyl-CoA and NADPH%3B multifunctional protein with several catalytic activities and an acyl carrier protein%3B enriched in gametes
chr2	5119568	5120331	+	DDB_G0275071	fahd1	ortholog of the human FAHD1 protein
chr2	5120434	5124359	-	DDB_G0275267	wrky1	contains two WRKY DNA-binding domains
chr2	5126494	5128119	+	DDB_G0275269	DDB_G0275269	NA
chr2	5128411	5130120	+	DDB_G0275073	pwp1	ortholog of H. sapiens and S. cerevisiae PWP1 involved in rRNA processing
chr2	5130987	5134105	+	DDB_G0275075	DDB_G0275075	ortholog of mammalian NARG1 and yeast NAT1%2C part of a complex that displays alpha (N-terminal) acetyltransferase activity 
chr2	5134435	5142355	-	DDB_G0275077	pks17	fatty acid synthases catalyze the formation of long-chain fatty acids from acetyl-CoA%2C malonyl-CoA and NADPH. This multifunctional protein has several catalytic activities and an acyl carrier protein
chr2	5143836	5146781	-	DDB_G0275165	DDB_G0275165	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family
chr2	5147013	5147361	+	DDB_G0275201	DDB_G0275201	NA
chr2	5147676	5148224	-	DDB_G0275079	hspG1	NA
chr2	5148814	5149239	+	DDB_G0275081	DDB_G0275081	similar to bacterial proteins of the YjgF superfamily%3B homolog of Psedomonas sp. amnD (2-aminomuconate deaminase)%3B also matches PFAM HMM for endoribonuclease L-PSP
chr2	5150001	5150633	+	DDB_G0275271	DDB_G0275271	weakly similar to comFC protein from Clostridium perfringens SM101
chr2	5150712	5152071	-	DDB_G0275273	DDB_G0275273	NA
chr2	5152512	5152835	-	DDB_G0275163	DDB_G0275163	NA
chr2	5153248	5153718	-	DDB_G0275083	DDB_G0275083	NA
chr2	5154689	5157539	+	DDB_G0275085	gacFF	NA
chr2	5161132	5162962	+	DDB_G0275275	DDB_G0275275	NA
chr2	5163252	5164865	+	DDB_G0275087	DDB_G0275087	NA
chr2	5165037	5166886	-	DDB_G0275089	DDB_G0275089	NA
chr2	5167778	5169757	+	DDB_G0275277	DDB_G0275277	NA
chr2	5170228	5171282	-	DDB_G0275279	DDB_G0275279	member of a gene family comprising %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283887%22%3E%3Ci%3EDDB_G0283887%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283885%22%3E%3Ci%3EDDB_G0283885%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275891%22%3E%3Ci%3EDDB_G0275891_ps%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275279%22%3E%3Ci%3EDDB_G0275279%3C%2Fi%3E%3C%2Fa%3E%2C similar to hypothetical protein MT3488 from Mycobacterium tuberculosis
chr2	5171836	5171924	-	DDB_G0294975	tRNA-Gln-CUG-1	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5172500	5174591	+	DDB_G0275091	DDB_G0275091	contains one predicted coiled-coil domain%3B similar to D. purpureum protein
chr2	5178139	5179801	+	DDB_G0275021	ubpB	ubiquitin carboxyl-terminal hydrolase shown to deubiquinate %3Ci%3EmkkA%3C%2Fi%3E%3B putative ortholog of H. sapiens USP10
chr2	5180306	5180620	-	DDB_G0275151	DDB_G0275151	NA
chr2	5181844	5182767	+	DDB_G0275019	DDB_G0275019	NA
chr2	5183368	5185287	-	DDB_G0275017	DDB_G0275017	contains a MOZ%2FSAS-like domain (Monocytic leukemia Zinc finger%2FSomething About Silencing) predicted to have histone acetyltransferase activity
chr2	5186347	5189886	+	DDB_G0275015	DDB_G0275015	NA
chr2	5190004	5191121	-	DDB_G0275013	omt4	NA
chr2	5192598	5195773	-	DDB_G0275283	DDB_G0275283	NA
chr2	5197716	5197787	-	DDB_G0294973	tRNA-Asp-GUC-11	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr2	5198095	5200377	+	DDB_G0275285	DDB_G0275285	NA
chr2	5201034	5203064	+	DDB_G0275197	cyp518B1	NA
chr2	5203376	5203939	-	DDB_G0275161	DDB_G0275161	NA
chr2	5204831	5206231	+	DDB_G0275159	DDB_G0275159	probable ortholog of H. sapiens and S. cerevisiae HAT1%2C a subunit of the HAT1%2FHAT2 histone acetyltransferase complex
chr2	5206472	5210492	-	DDB_G0275195	DDB_G0275195	NA
chr2	5211773	5217123	+	DDB_G0275011	pikC	NA
chr2	5217220	5217948	-	DDB_G0275157	limF	contains three LIM domain repeats
chr2	5218487	5225348	-	DDB_G0275287	DDB_G0275287	NA
chr2	5225979	5228895	-	DDB_G0275289	DDB_G0275289	NA
chr2	5230828	5235376	+	DDB_G0275009	gcA	NA
chr2	5236396	5238691	+	DDB_G0275007	cmfA	NA
chr2	5239346	5240349	+	DDB_G0275053	DDB_G0275053	belongs to the NADP_Rossman superfamily%3B similar to human NMRAL1%3B A. nidulans nmrA is a transcriptional regulator involved in nitrogen metabolite repression
chr2	5240500	5240799	-	DDB_G0275051	DDB_G0275051_ps	putative pseudogene%3B hssA%2F2C%2F7E family protein
chr2	5241548	5241989	-	DDB_G0275193	hdaC_ps3	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0280195%22%3E%3Ci%3EhdaC%3C%2Fi%3E%3C%2Fa%3E
chr2	5242381	5242610	+	DDB_G0275291	DDB_G0275291	NA
chr2	5243218	5244505	+	DDB_G0275293	p2xB	member of the  %3Ci%3EDictyostelium%3C%2Fi%3E P2X receptor family%3B membrane ion channel activated by ATP%3B may be involved in intracellular calcium signaling
chr2	5246055	5247567	+	DDB_G0275191	p2xC	member of the Dictyostelium P2X receptor family but ATP-gated ion channel activity could not be demonstrated
chr2	5249449	5250533	+	DDB_G0275049	DDB_G0275049	NA
chr2	5250735	5251439	-	DDB_G0275047	DDB_G0275047	NA
chr2	5253249	5254548	+	DDB_G0275295	galE	catalyzes the reaction UDP-glucose %3C%3D%3E UDP-galactose%3B expressed in prespore cells
chr2	5256632	5257604	+	DDB_G0275189	DDB_G0275189	NA
chr2	5260668	5262157	+	DDB_G0275155	DDB_G0275155	NA
chr2	5262569	5265160	-	DDB_G0275185	gacI	NA
chr2	5266629	5267764	+	DDB_G0275045	gpbB	plays a role in growth and development
chr2	5268701	5268886	+	DDB_G0275043	DDB_G0275043	NA
chr2	5270344	5271611	+	DDB_G0275297	DDB_G0275297	NA
chr2	5272269	5273564	+	DDB_G0275299	cln5	ortholog of Cln5%2C implicated in neuronal ceroid lipofuscinoses neurodegenerative disorders
chr2	5273798	5274823	+	DDB_G0275041	DDB_G0275041	NA
chr2	5275007	5276312	-	DDB_G0275301	DDB_G0275301	NA
chr2	5276826	5278156	-	DDB_G0295775	DDB_G0295775	has similarity to the plant importin alpha chain%2C subunit of a protein transporter
chr2	5278271	5280648	-	DDB_G0275039	DDB_G0275039	conserved hypothetical protein%3B contains 13 predicted transmembrane domains and a partial endonuclease%2Fexonuclease%2Fphosphatase domain
chr2	5281471	5286945	-	DDB_G0275303	DDB_G0275303	NA
chr2	5288579	5288668	+	DDB_G0294857	tRNA-Thr-UGU-1	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5290018	5290088	-	DDB_G0294971	tRNA-His-GUG-5	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5290527	5293516	-	DDB_G0275183	fnkF_ps	putative pseudogene%3B STE%2FFNIP protein kinase family
chr2	5293775	5300728	-	DDB_G0275035	zizA	zizimin- related DOCK family protein
chr2	5302345	5311304	+	DDB_G0275305	DDB_G0275305	ortholog of human hypothetical protein Q9Y3N6
chr2	5311440	5313684	-	DDB_G0275033	DDB_G0275033	conserved hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E protein
chr2	5314110	5314182	-	DDB_G0294969	tRNA-Met-CAU-8	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5315972	5316184	+	DDB_G0275031	DDB_G0275031	NA
chr2	5316981	5318500	+	DDB_G0275029	odhB	catalyzes the reaction succinyl-CoA %2B enzyme N6-(dihydrolipoyl)lysine %3D CoA %2B enzyme N6-(S-succinyldihydrolipoyl) lysine%3B E2 component of the multienzyme 2-oxoglutarate dehydrogenase complex
chr2	5319128	5320028	-	DDB_G0275307	DDB_G0275307	NA
chr2	5320535	5322385	-	DDB_G0275309	DDB_G0275309	NA
chr2	5323069	5323344	-	DDB_G0275027	DDB_G0275027	NA
chr2	5324765	5325948	+	DDB_G0275153	gpdA	NA
chr2	5326205	5327517	+	DDB_G0275025	DDB_G0275025	contains one thioredoxin domain%3B similar to human PDIA6 (protein disulfide isomerase A6)
chr2	5327661	5328276	-	DDB_G0275181	mcee	catalyzes the reaction L-methylmalonyl-CoA %3C%3D%3E D-methylmalonyl-CoA
chr2	5329126	5331271	+	DDB_G0275311	DDB_G0275311	catalyzes the condensation of acetyl-CoA and oxaloacetate to citrate
chr2	5331812	5336775	-	DDB_G0275313	dhx9	ortholog of the human DHX9%2C that unwinds double-stranded DNA and RNA in a 3%27 to 5%27 direction
chr2	5337299	5338585	-	DDB_G0275315	DDB_G0275315	similar to Polysphondylium pallidum protein
chr2	5339600	5340709	+	DDB_G0275317	DDB_G0275317	NA
chr2	5341225	5342916	-	DDB_G0275319	DDB_G0275319	NA
chr2	5343575	5344705	+	DDB_G0275023	act22	has 94%25 identity with human beta-actin (SwissProt P60709) and 4 amino acid differences compared to the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)
chr2	5345936	5347649	+	DDB_G0275179	DDB_G0275179	similar to %3Ci%3EH. sapiens%3C%2Fi%3E CECR1 protein (Swiss Prot Q9NZK5)
chr2	5348199	5350112	+	DDB_G0275321	DDB_G0275321	NA
chr2	5350193	5350454	-	DDB_G0275325	DDB_G0275325	NA
chr2	5352310	5353644	+	DDB_G0275327	rabX	NA
chr2	5354537	5357152	-	DDB_G0275393	DDB_G0275393	NA
chr2	5357606	5358302	+	DDB_G0275329	DDB_G0275329	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0287403%22%3E%3Ci%3EDDB_G0287403%3C%2Fi%3E%3C%2Fa%3E
chr2	5358648	5362937	-	DDB_G0275395	eIF4g	homolog of mammalian EIF4G1%2F2%2F3 and S. cerevisiae TIF4631%3B component of the protein complex eIF4F involved in the recognition of the mRNA cap
chr2	5365929	5369465	+	DDB_G0275331	DDB_G0275331	contains ARM repeat domain and 4 coiled-coil domains
chr2	5369983	5371533	-	DDB_G0275333	DDB_G0275333	NA
chr2	5375069	5381793	+	DDB_G0275399	DDB_G0275399	NA
chr2	5382119	5382860	+	DDB_G0275335	DDB_G0275335	similar to Homo sapiens activated RNA polymerase II transcriptional coactivator p15 (SwissProt P53999)
chr2	5383223	5384380	+	DDB_G0275337	DDB_G0275337	NA
chr2	5385395	5390751	+	DDB_G0275401	DDB_G0275401	NA
chr2	5391099	5392406	+	DDB_G0275339	DDB_G0275339	NA
chr2	5392651	5393822	+	DDB_G0275341	DDB_G0275341	NA
chr2	5393905	5395542	-	DDB_G0275343	DDB_G0275343	NA
chr2	5397156	5399539	+	DDB_G0275345	DDB_G0275345	NA
chr2	5399825	5400406	-	DDB_G0275347	DDB_G0275347	NA
chr2	5400772	5400844	-	DDB_G0294967	tRNA-Lys-CUU-4	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5401406	5401723	+	DDB_G0275349	DDB_G0275349	NA
chr2	5402357	5403020	+	DDB_G0275351	DDB_G0275351	contains 1 C2H2-type zinc finger%3B homolog of human ZNF593 and S. cerevisiae BUD20 (bud site selection protein 20) 
chr2	5403180	5405487	-	DDB_G0275403	DDB_G0275403	similar to human NOC4L%3B belongs to the CBF%2FMAK21 family%3B contains a CCAAT-binding_factor domain 
chr2	5406103	5408018	+	DDB_G0275323	tipD	ortholog of the mammalian ATG16l1%2C which is involved in autophagy%3B defects in human cause inflammatory bowel disease type 10%3B in D. discoideum involved in early development and tip formation
chr2	5409975	5411608	+	DDB_G0275353	DDB_G0275353	NA
chr2	5412017	5412878	-	DDB_G0275405	ap3s1	NA
chr2	5413401	5415816	+	DDB_G0275355	pccA	catalyzes the reaction ATP %2B HCO%3Csub%3E3%3C%2Fsub%3E%3Csup%3E-%3C%2Fsup%3E %2B propionyl-CoA %3C%3D%3E ADP %2B phosphate %2B D-methylmalonyl-CoA
chr2	5416778	5416850	-	DDB_G0294965	tRNA-Met-CAU-7	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5417695	5417970	-	DDB_G0275357	DDB_G0275357	NA
chr2	5420626	5421449	-	DDB_G0275407	txnl4a	U5 snRNP protein that is similar to thioredoxin but lacks protein disulfide isomerase activity
chr2	5421845	5424350	+	DDB_G0275409	DDB_G0275409	NA
chr2	5424566	5425954	-	DDB_G0275359	DDB_G0275359	NA
chr2	5426347	5427337	-	DDB_G0275363	DDB_G0275363_ps	putative pseudogene%3B fragment%3B similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0284105%22%3EDDB_G0284105%3C%2Fa%3E
chr2	5428576	5430860	+	DDB_G0275365	DDB_G0275365	NA
chr2	5431261	5432380	-	DDB_G0275411	DDB_G0275411	expressed in pstAO cells
chr2	5434710	5435080	-	DDB_G0275367	DDB_G0275367	similar to uncharacterized%2C eukaryotic proteins of the DUF1909 (4F5) family
chr2	5435452	5439452	-	DDB_G0275413	DDB_G0275413	contains two transmembrane domains
chr2	5440439	5449952	+	DDB_G0275415	DDB_G0275415	similar to ubiquitin specific protease 34 (USP34)
chr2	5450465	5451672	+	DDB_G0275417	DDB_G0275417	NA
chr2	5451865	5452005	-	DDB_G0275369	DDB_G0275369	NA
chr2	5452266	5452337	-	DDB_G0294963	tRNA-Glu-UUC-9	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr2	5452633	5453727	+	DDB_G0275371	DDB_G0275371	similar to the esterase encoded by %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0287647%22%3E%3Ci%3EDDB_G0287647%3C%2Fi%3E%3C%2Fa%3E
chr2	5454647	5454718	-	DDB_G0294961	tRNA-Glu-UUC-8	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr2	5454847	5456469	-	DDB_G0275419	DDB_G0275419	contains a predicted signal peptide%3B similarity to bacterial NUDIX hydrolases and dipeptidyl-peptidases
chr2	5459788	5463748	+	DDB_G0275421	DDB_G0275421	contains 2 GRAM domains%3B one RabGAP%2FTBC domain and one EF hand domain
chr2	5465798	5467190	+	DDB_G0275423	DDB_G0275423	NA
chr2	5467402	5468851	-	DDB_G0275373	DDB_G0275373	NA
chr2	5469261	5475029	-	DDB_G0275375	DDB_G0275375	NA
chr2	5475784	5476722	+	DDB_G0275377	DDB_G0275377	contains one putative transmembrane domain
chr2	5477021	5477302	-	DDB_G0275379	DDB_G0275379	contains no functional domains and is not similar to any other protein
chr2	5477733	5478109	-	DDB_G0275381	DDB_G0275381	belongs to the RAMP4 (ribosome-associated membrane protein) family%3B homolog of human SERP1 (stress-associated endoplasmic reticulum protein)%3B contains one predicted transmembrane domain
chr2	5478950	5479561	+	DDB_G0275429	syn8A	member of the SNARE family (Soluble NSF Attachment Protein REceptor)%3B localizes to endosome and interacts with syn7A
chr2	5480068	5480423	-	DDB_G0275383	DDB_G0275383	similar to small genes conserved in plants%3B contains one central transmembrane domain
chr2	5482191	5482952	+	DDB_G0275385	DDB_G0275385	catalyses the posttranslational hydroxylation of peptides or proteins
chr2	5483235	5488130	-	DDB_G0275431	DDB_G0275431	NA
chr2	5488651	5489135	+	DDB_G0275433	DDB_G0275433	similar to D. purpureum protein
chr2	5489684	5489764	-	DDB_G0294959	tRNA-Leu-CAA-3	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5492551	5492631	+	DDB_G0294859	tRNA-Leu-CAA-1	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5493095	5494702	+	DDB_G0275389	DDB_G0275389	NA
chr2	5495060	5499588	-	DDB_G0275391	tacc	promotes microtubule growth%3B localizes to the centromer and has been shown to physically interact with %3Ca href%3D%22%2Fgene%2FDDB_G0268616%22%3EDdCP224%3C%2Fa%3E
chr2	5500328	5500596	-	DDB_G0275435	DDB_G0275435	NA
chr2	5502985	5503561	-	DDB_G0275949	DDB_G0275949	NA
chr2	5504962	5505863	-	DDB_G0275691	DDB_G0275691	NA
chr2	5506678	5511084	+	DDB_G0275563	DDB_G0275563	NA
chr2	5513128	5516287	-	DDB_G0275809	msh2	MSH2 ortholog
chr2	5516663	5517259	-	DDB_G0275565	DDB_G0275565	NA
chr2	5517792	5519439	+	DDB_G0275567	amd1	catalyzes the removal of the carboxylate group of S-adenosylmethionine to form S-adenosyl-5%27-3-methylpropylamine%2C which then acts as the n-propylamine group donor in the synthesis of the polyamines spermidine and spermine%3Cbr%3E %3Cb%3ENomenclature conflict: %3C%2Fb%3E Do not confuse this gene with amdA%2C encoding AMP deaminase
chr2	5519854	5520906	-	DDB_G0275569	DDB_G0275569	NA
chr2	5522231	5525118	+	DDB_G0275571	DDB_G0275571	NA
chr2	5525678	5526530	+	DDB_G0275573	vps32	involved in vesicle trafficking in yeast and mammals%3B expressed in endosome
chr2	5526799	5529042	-	DDB_G0275813	DDB_G0275813	NA
chr2	5530051	5531034	+	DDB_G0275575	DDB_G0275575	NA
chr2	5531426	5533708	+	DDB_G0275693	DDB_G0275693	NA
chr2	5533870	5536035	-	DDB_G0275577	DDB_G0275577	NA
chr2	5536603	5538492	+	DDB_G0275815	nrampB	NRAMP family protein similar to bacterial manganese transport protein mntH%3B contains 12 transmembrane domains%3B involved in iron homeostasis and resistance to pathogenic bacteria
chr2	5538592	5538990	-	DDB_G0275579	DDB_G0275579	NA
chr2	5539448	5539792	-	DDB_G0275817	DDB_G0275817	weakly similar to hssA%2F2C%2F7E family genes 
chr2	5541223	5541593	-	DDB_G0275819	DDB_G0275819	weakly similar to hssA%2F2C%2F7E family genes
chr2	5541988	5544369	-	DDB_G0275821	DDB_G0275821	NA
chr2	5544915	5545293	+	DDB_G0275807	DDB_G0275807	NA
chr2	5545999	5546387	+	DDB_G0275437	7E	cyclic AMP-regulated gene
chr2	5546562	5550298	-	DDB_G0275823	ptcI	NA
chr2	5550573	5553308	-	DDB_G0275581	DDB_G0275581	NA
chr2	5553795	5554523	-	DDB_G0275583	DDB_G0275583	NA
chr2	5554964	5556559	+	DDB_G0275585	DDB_G0275585	NA
chr2	5556745	5556998	-	DDB_G0275587	DDB_G0275587	NA
chr2	5559641	5559920	+	DDB_G0275825	DDB_G0275825	conserved hypothetical Dictyostelium protein%3B contains no functional protein domains
chr2	5560910	5561178	+	DDB_G0275827	DDB_G0275827	NA
chr2	5561391	5561996	-	DDB_G0275829	DDB_G0275829	NA
chr2	5562777	5564858	+	DDB_G0275591	DDB_G0275591	NA
chr2	5565701	5568269	+	DDB_G0275805	DDB_G0275805	NA
chr2	5568361	5569581	-	DDB_G0275593	DDB_G0275593	similar to bacterial 2-nitropropane dioxygenases
chr2	5570659	5571840	+	DDB_G0275803	DDB_G0275803_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0275143%22%3EDDB_G0275143%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269090%22%3EDDB_G0269090%3C%2Fa%3E
chr2	5571932	5573983	-	DDB_G0275595	DDB_G0275595	NA
chr2	5574827	5576149	+	DDB_G0275801	DDB_G0275801	contains two putative WWE domains%2C which are predicted to mediate protein-protein interactions in ubiquitin and ADP ribose conjugation systems
chr2	5576194	5576772	-	DDB_G0275799	DDB_G0275799	NA
chr2	5577263	5577580	+	DDB_G0275597	DDB_G0275597	NA
chr2	5578081	5578296	+	DDB_G0275831	DDB_G0275831	NA
chr2	5578557	5579324	-	DDB_G0275599	DDB_G0275599	NA
chr2	5580042	5581874	+	DDB_G0275601	ltv1	similar to metazoan LVT proteins%2C whose function is unknown
chr2	5581974	5582882	-	DDB_G0275835	DDB_G0275835	NA
chr2	5583526	5585615	+	DDB_G0275603	DDB_G0275603	NA
chr2	5585797	5587674	-	DDB_G0275605	DDB_G0275605_ps	putative pseudogene%3B similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0270342%22%3EDDB_G0270342%3C%2Fa%3E
chr2	5588037	5588891	-	DDB_G0275695	ampA	anti-adhesion molecule that limits cell-cell and cell-substrate adhesion during development
chr2	5590467	5593823	-	DDB_G0275697	abcH3	consists of one ABC domain and lacks a transmembrane domain
chr2	5594155	5594499	-	DDB_G0275609	DDB_G0275609	NA
chr2	5595268	5596116	+	DDB_G0275797	DDB_G0275797	NA
chr2	5596338	5598865	-	DDB_G0275795	DDB_G0275795	NA
chr2	5600309	5603926	+	DDB_G0275447	myoD	class I  (unconventiona) myosin%3B component of actin-based molecular motor
chr2	5604371	5604982	+	DDB_G0349375	DDB_G0349375	NA
chr2	5605276	5606462	+	DDB_G0349377	DDB_G0349377	NA
chr2	5606831	5608318	+	DDB_G0275613	DDB_G0275613	NA
chr2	5609342	5609864	-	DDB_G0275615	DDB_G0275615_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0268186%22%3EDDB_G0268186%3C%2Fa%3E 
chr2	5611769	5613568	-	DDB_G0275793	DDB_G0275793	NA
chr2	5613948	5615334	+	DDB_G0275699	gnt1	catalyzes the addition of GlcNAc (N-acetylglucosamine) to HyPro143-Skp1 (FpaA%2FFpaB) in the cytosol
chr2	5615906	5616508	+	DDB_G0275791	DDB_G0275791	NA
chr2	5616700	5616780	-	DDB_G0349518	DDB_G0349518	NA
chr2	5616992	5617730	-	DDB_G0275557	DDB_G0275557	NA
chr2	5618738	5619736	+	DDB_G0275559	DDB_G0275559	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr2	5620256	5623997	+	DDB_G0275789	DDB_G0275789	NA
chr2	5624593	5627192	+	DDB_G0275561	fnkA	protein kinase%2C STE group
chr2	5627352	5645601	-	DDB_G0295765	mdn1	%3Ci%3EDictyostelium%3C%2Fi%3E ortholog of the conserved midasin%2C a large protein containing an AAA%2B ATPase domain and a C-terminal VWFA domain%3B %3Ci%3ES. cerevisiae%3C%2Fi%3E MDN1 is a rRNA processing ATPase.
chr2	5646909	5648070	+	DDB_G0275787	rad6	RAD6 homolog%2C an E2 ubiquitin-conjugating enzyme involved in postreplication repair%3B forms a heterodimer with RAD18
chr2	5648871	5649906	+	DDB_G0275549	DDB_G0275549	NA
chr2	5650203	5652737	-	DDB_G0275785	DDB_G0275785	NA
chr2	5653320	5655053	+	DDB_G0275783	DDB_G0275783	contains a predicted signal anchor%3B contains 3 coiled coil domains
chr2	5655917	5656376	-	DDB_G0275551	DDB_G0275551	NA
chr2	5657920	5661235	-	DDB_G0275843	DDB_G0275843	NA
chr2	5665840	5673077	+	DDB_G0275845	smg1	atypical%2C PIKK family protein kinase%3B similar to the PI-3-kinase-related kinase SMG1%2C which functions in nonsense-mediated mRNA decay%3B belongs to the PIKK family of protein kinases
chr2	5673341	5674413	-	DDB_G0275847	DDB_G0275847	belongs to the UPF0568 family%3B homolog of human C14orf166
chr2	5674643	5675653	-	DDB_G0275553	DDB_G0275553	NA
chr2	5676909	5677527	-	DDB_G0275849	DDB_G0275849	conserved small protein of unknown function%3B contains two predicted transmembrane domains
chr2	5678003	5679062	+	DDB_G0275851	DDB_G0275851	has similarity to human OS-9%2C a protein that might play a role in the ER-associated degradation of misfolded glycoproteins
chr2	5679309	5680331	-	DDB_G0275701	vatE	ortholog of the E subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the E subunit is part of the V1 subunit
chr2	5681724	5684456	+	DDB_G0275777	DDB_G0275777	similar to D. purpureum protein
chr2	5684935	5685657	+	DDB_G0275555	DDB_G0275555	NA
chr2	5687040	5688368	+	DDB_G0275671	DDB_G0275671	putative serine esterase%3B similar to hypothetical proteins in plants and yeast
chr2	5689186	5690969	+	DDB_G0275775	psmD4	contains one von Willebrand factor%2C type A (VWFA) domain and two ubiquitin interacting motifs
chr2	5691217	5694086	-	DDB_G0275853	DDB_G0275853	conserved protein%3B contains 11 putative transmembrane domains
chr2	5694864	5695226	+	DDB_G0275673	DDB_G0275673	NA
chr2	5696031	5696705	+	DDB_G0275675	rab32C	NA
chr2	5697759	5699765	-	DDB_G0275855	DDB_G0275855	NA
chr2	5700254	5701642	-	DDB_G0275677	DDB_G0275677	NA
chr2	5702027	5704162	-	DDB_G0275445	mybB	contains three Myb DNA-binding domains
chr2	5709701	5714246	-	DDB_G0275679	gxcJJ	NA
chr2	5715872	5716161	+	DDB_G0275681	DDB_G0275681	NA
chr2	5716350	5718112	-	DDB_G0275773	DDB_G0275773	NA
chr2	5719223	5720429	+	DDB_G0275683	DDB_G0275683	NA
chr2	5720646	5720795	-	DDB_G0275685	DDB_G0275685	NA
chr2	5722920	5723915	-	DDB_G0275859	DDB_G0275859	NA
chr2	5724705	5725465	+	DDB_G0275537	cytC	NA
chr2	5727073	5731156	-	DDB_G0275539	DDB_G0275539	NA
chr2	5731969	5733150	+	DDB_G0275541	DDB_G0275541	NA
chr2	5733694	5734524	+	DDB_G0275767	DDB_G0275767	contains an EGF-like (epidermal growth factor-like) domain found in extracellular proteins
chr2	5735439	5736097	-	DDB_G0275765	DDB_G0275765	NA
chr2	5736589	5737692	+	DDB_G0275543	DDB_G0275543	NA
chr2	5741117	5744830	+	DDB_G0275703	gefN	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form
chr2	5745037	5753130	-	DDB_G0275861	DDB_G0275861	conserved eukaryotic protein
chr2	5754202	5754495	+	DDB_G0275545	DDB_G0275545	NA
chr2	5754874	5759577	-	DDB_G0275687	abcG18	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr2	5760590	5764773	-	DDB_G0275689	abcG2	full transporter%2C consisting of two ABC domains and two transmembrane domains%3B involved in pH maintenance
chr2	5767351	5768015	-	DDB_G0305357	rfk	catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN)
chr2	5768614	5769966	+	DDB_G0275863	nmt	catalyzes the reaction tetradecanoyl-CoA %2B glycylpeptide %3D CoA %2B N-tetradecanoylglycylpeptide
chr2	5770895	5772029	+	DDB_G0275547	DDB_G0275547	NA
chr2	5772751	5774334	-	DDB_G0275865	DDB_G0275865	NA
chr2	5776448	5779105	+	DDB_G0275867	DDB_G0275867	NA
chr2	5779278	5780222	+	DDB_G0275763	DDB_G0275763	NA
chr2	5780689	5784247	-	DDB_G0275443	helB1	conserved RNA helicase%3B  S. cerevisiae ortholog PRP5 is necessary for pre-spliceosome formation
chr2	5784538	5786400	-	DDB_G0275669	DDB_G0275669	involved in proline metabolism%3B catalyzes the reaction L-proline %2B acceptor %3D (S)-1-pyrroline-5-carboxylate %2B reduced acceptor
chr2	5787522	5788532	-	DDB_G0275667	DDB_G0275667	homolog of human and S. cerevisiae KTI12 (killer toxin insensitivity protein 12)%3B S. cerevisiae KTI12 interacts with the Elongator complex%2C a component of the elongating form of RNA polymerase II 
chr2	5788919	5789287	+	DDB_G0275761	DDB_G0275761	NA
chr2	5789524	5790435	-	DDB_G0275665	DDB_G0275665	NA
chr2	5791228	5792163	+	DDB_G0275663	ippA	converts 1D-myo-inositol 1%2C4-bisphosphate %2B H2O to 1D-myo-inositol 4-phosphate %2B phosphate
chr2	5793308	5796113	+	DDB_G0275869	DDB_G0275869	NA
chr2	5796327	5799964	-	DDB_G0275871	DDB_G0275871	contains ten transmembrane domains
chr2	5800903	5804775	-	DDB_G0275873	DDB_G0275873	NA
chr2	5806627	5808015	+	DDB_G0275661	DDB_G0275661	NA
chr2	5808489	5813651	+	DDB_G0275759	rpa1	component of the RNA polymerase I complex%3B ortholog of S. cerevisiae RPA190
chr2	5814130	5814840	+	DDB_G0275951	DDB_G0275951	contains 4 transmembrane domains
chr2	5815544	5818897	+	DDB_G0275659	DDB_G0275659	NA
chr2	5819427	5819678	+	DDB_G0275757	DDB_G0275757_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0285583%22%3EDDB_G0285583%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0285477%22%3EDDB_G0285477%3C%2Fa%3E
chr2	5820628	5820729	-	DDB_G0275657	rps28_ps	putative pseudogene%3B short fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0285597%22%3E%3Ci%3Erps28%3C%2Fi%3E%3C%2Fa%3E
chr2	5820963	5821049	-	DDB_G0294957	tRNA-Trp-CCA-7	transfers a tryptophan residue to a growing polypeptide chain during protein synthesis%0A
chr2	5822886	5824333	-	DDB_G0275441	gtpA	similar to plant translocase of chloroplast 34 (TOC34)
chr2	5828810	5835178	+	DDB_G0275875	DDB_G0275875	similar to a D. purpureum gene
chr2	5835586	5838483	+	DDB_G0275655	malaS	catalyzes the reaction ATP %2B L-alanine %2B tRNAAla %3D AMP %2B diphosphate %2B L-alanyl-tRNAAla
chr2	5838829	5843021	+	DDB_G0275879	fnkE	protein kinase domain similar to those of the mitogen-activated protein kinases%2C which belong to the STE20 family%3B contains two protein kinase domains%2C one of which is predicted to be inactive%3B contains several FNIP repeats
chr2	5843218	5846253	-	DDB_G0275653	xrcc1	putative ortholog of XRCC1%2C which is involved in single-strand break repair%3B interacts with DNA ligase III
chr2	5846616	5847506	-	DDB_G0275755	DDB_G0275755	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr2	5847867	5850695	-	DDB_G0275651	elp2	similar to S. cerevisiae ELP2%2C subunit of the RNA polymerase II elongator complex
chr2	5851635	5853013	-	DDB_G0275753	psmD9	NA
chr2	5854199	5856444	+	DDB_G0275649	DDB_G0275649	NA
chr2	5856743	5857784	-	DDB_G0275449	natA	NA
chr2	5858199	5858788	-	DDB_G0275647	DDB_G0275647	similar to cytochrome B5 reductase but missing the carboxyl terminus containing the reductase domain
chr2	5859116	5859523	+	DDB_G0275645	acn9	ortholog of the conserved ACN9%2C in S. cerevisiae localized to the mitochondrial intermembrane space and required for acetate utilization and gluconeogenesis
chr2	5859705	5862840	-	DDB_G0275751	DDB_G0275751	belongs to the IF-2 family%3B an essential component for the initiation of protein synthesis
chr2	5863253	5864166	-	DDB_G0275749	DDB_G0275749	NA
chr2	5864931	5866205	+	DDB_G0275643	DDB_G0275643	NA
chr2	5868742	5872573	+	DDB_G0275535	DDB_G0275535	contains eight transmembrane domains
chr2	5872794	5875616	-	DDB_G0275747	DDB_G0275747	contains a predicted signal sequence and a putative C-terminal transmembrane domain
chr2	5876511	5877654	+	DDB_G0275881	rpl13a	protein component of the large (60S) ribosomal subunit
chr2	5877842	5880618	-	DDB_G0275745	tgrR1	contains a predicted signal peptide and a C-terminal transmembrane domain
chr2	5881476	5882830	-	DDB_G0275743	DDB_G0275743	NA
chr2	5884722	5885495	+	DDB_G0275741	dio3	contains a selenocysteine (U) residue at position 113%3B similar to animal Type III iodothyronine deiodinase (DIO3)%3B catalyzes the reaction 3%2C3%27%2C5%27-triiodo-L-thyronine %2B iodide %2B A %2B H(%2B) %3D L-thyroxine %2B AH(2)
chr2	5885784	5886805	-	DDB_G0275885	DDB_G0275885	NA
chr2	5887655	5889688	+	DDB_G0275739	DDB_G0275739	contains one HEAT repeat region%3B similar to D. purpureum protein
chr2	5891053	5891580	+	DDB_G0275527	DDB_G0275527	NA
chr2	5892491	5896938	-	DDB_G0275529	DDB_G0275529	NA
chr2	5899852	5901855	+	DDB_G0275737	DDB_G0275737	NA
chr2	5903117	5904832	+	DDB_G0275887	masA	catalyzes the reaction acetyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO %2B glyoxylate %3C%3D%3E malate %2B coenzyme A%3B expressed in pstAB and pstO cells and in upper cup during culmination
chr2	5905995	5906888	+	DDB_G0275735	DDB_G0275735	NA
chr2	5907958	5908030	-	DDB_G0294955	tRNA-Gln-UUG-9	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5908177	5908383	-	DDB_G0275531	DDB_G0275531	NA
chr2	5909271	5912372	-	DDB_G0275533	DDB_G0275533	NA
chr2	5914994	5922255	+	DDB_G0275733	med26	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 26%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr2	5922492	5923304	-	DDB_G0275525	hspK	NA
chr2	5924463	5928957	+	DDB_G0275889	DDB_G0275889	ortholog of human HPS3%3B mutations in human HPS3 have been linked to Hermansky-Pudlak syndrome 3 
chr2	5929362	5930136	+	DDB_G0275891	DDB_G0275891_ps	putative pseudogene%3B member of a gene family comprising %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283887%22%3E%3Ci%3EDDB_G0283887%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283885%22%3E%3Ci%3EDDB_G0283885%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275891%22%3E%3Ci%3EDDB_G0275891_ps%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275279%22%3E%3Ci%3EDDB_G0275279%3C%2Fi%3E%3C%2Fa%3E%2C similar to hypothetical protein MT3488 from Mycobacterium tuberculosis
chr2	5930653	5933817	-	DDB_G0275893	DDB_G0275893	NA
chr2	5934172	5934244	-	DDB_G0294953	tRNA-Asn-GUU-9	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5934525	5936105	+	DDB_G0275621	DDB_G0275621	NA
chr2	5936245	5938905	-	DDB_G0275623	mcm4	similar to MCM4%2C a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
chr2	5939682	5940473	+	DDB_G0275895	cchl	catalyzes the covalent attachment of a heme group on two cysteine residues of cytochrome c and c1%3B defects in the human gene causes syndromic microphthalmia 7 (MCOPS7) syndrome%2C an X-linked dominant disorder characterized by unilateral or bilateral microphthalmia and linear skin defects
chr2	5940660	5945217	-	DDB_G0275731	iqgD	similar to RasGAP proteins%3B contains one calponin homology domain and one rasGAP domain
chr2	5946993	5947050	+	DDB_G0295513	r41	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr2	5947196	5947266	-	DDB_G0294951	tRNA-His-GUG-4	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr2	5947660	5948535	+	DDB_G0275625	DDB_G0275625	NA
chr2	5948745	5951541	-	DDB_G0275451	alxA	similar to mammalian Alix%2C which interacts with ALG-2 (apoptosis-linked gene 2)%3B contains 1 BRO1 (Bro1-rhophilin) domain%2C 3 coiled-coil regions%2C 1 proline-rich region%2C and a conserved recognition sequence for Src-type tyrosine kinases
chr2	5951942	5953912	-	DDB_G0275627	sky1	similar to SRPKs (Serine%2Farginine-Rich Protein specific Kinases)%2C serine%2Fthreonine kinases that specifically phosphoryate arginine-serine rich domains found in the SR family of splicing factors
chr2	5954835	5955486	+	DDB_G0275629	DDB_G0275629	NA
chr2	5956945	5959251	+	DDB_G0275631	DDB_G0275631	the protein phosphatase 2C-related domain occurs in protein phosphatase 2C (PPC2) as well as in other proteins%2C such as pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase
chr2	5960620	5964001	+	DDB_G0275897	DDB_G0275897	putative pseudogene%3B similar to a large gene family encoding FNIP repeat-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290067%22%3E%3Ci%3EcigB%3C%2Fi%3E%3C%2Fa%3E 
chr2	5966046	5966089	-	DDB_G0295515	r44	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr2	5966546	5970367	-	DDB_G0275899	DDB_G0275899	contains 12 putative transmembrane domains%3B similar to D. purpureum protein
chr2	5972320	5975825	+	DDB_G0275633	DDB_G0275633	ortholog of human SKIV2L2 (SuperKIller Viralicitic 2L2) protein%2C and yeast MTR4%2C a helicase required for mRNA export from the nucleus
chr2	5976071	5976354	-	DDB_G0275901	DDB_G0275901	NA
chr2	5977948	5978728	-	DDB_G0275439	cad2	similar to cadA (cad1)%2C a calcium-binding cell-cell adhesion molecule
chr2	5981905	5982135	-	DDB_G0275903	DDB_G0275903	NA
chr2	5982746	5984503	+	DDB_G0275905	DDB_G0275905	NA
chr2	5985888	5986697	+	DDB_G0275725	DDB_G0275725	NA
chr2	5986809	5987189	-	DDB_G0275479	DDB_G0275479	NA
chr2	5987198	5987524	-	DDB_G0275723	DDB_G0275723	NA
chr2	5987883	5988230	-	DDB_G0275721	DDB_G0275721	NA
chr2	5988394	5990095	+	DDB_G0275481	DDB_G0275481	NA
chr2	5990519	5990773	+	DDB_G0275483	DDB_G0275483	NA
chr2	5991516	5991644	+	DDB_G0275485	DDB_G0275485	NA
chr2	5992334	5993365	+	DDB_G0275487	DDB_G0275487	NA
chr2	5994199	5994444	-	DDB_G0275489	DDB_G0275489	NA
chr2	5996541	5997069	+	DDB_G0275907	DDB_G0275907_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0275487%22%3EDDB_G0275487%3C%2Fa%3E
chr2	5997672	5997920	-	DDB_G0275491	DDB_G0275491	NA
chr2	5998936	5999307	+	DDB_G0275719	lsm6	member of heteromeric complexes involved in mRNA splicing (lsm2-8) and mRNA degradation (lsm1-7)
chr2	6000211	6001649	-	DDB_G0275493	cycB	similar to metazoan cyclin B%3B predicted to interact with the cyclin-dependent kinase CDK1%2F2 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272813%22%3E%3Ci%3Ecdk1%3C%2Fi%3E%3C%2Fa%3E)
chr2	6003763	6006258	-	DDB_G0275495	cepE	localizes to the centrosomal core structure
chr2	6007182	6009155	+	DDB_G0275497	DDB_G0275497	NA
chr2	6009402	6012149	+	DDB_G0275717	thoc1	ortholog of human THOC1 and yeast THO1%2C which exist in the THO complex required for transcriptional elongation
chr2	6013021	6013413	-	DDB_G0275909	DDB_G0275909	NA
chr2	6014515	6015313	+	DDB_G0275499	omt5	highly similar to bacterial O-methyltransferases
chr2	6015883	6016653	+	DDB_G0275501	omt6	highly similar to bacterial O-methyltransferases
chr2	6017175	6018008	+	DDB_G0275503	DDB_G0275503	NA
chr2	6018482	6022287	+	DDB_G0275505	DDB_G0275505	NA
chr2	6022499	6023089	-	DDB_G0275507	DDB_G0275507	similar to bacterial acetyltransferases%3B homolog of E. coli maa (maltose O-acetyltransferase)
chr2	6023716	6026322	+	DDB_G0275509	DDB_G0275509	NA
chr2	6026463	6026864	-	DDB_G0275511	DDB_G0275511	NA
chr2	6027807	6028964	-	DDB_G0275911	DDB_G0275911	NA
chr2	6029488	6030238	-	DDB_G0275913	DDB_G0275913	similar to bacterial acetyltransferases%3B homolog of E. coli maa (maltose O-acetyltransferase)%3B similar to D. purpureum protein
chr2	6030307	6031260	-	DDB_G0275915	DDB_G0275915	NA
chr2	6031763	6032185	-	DDB_G0275715	DDB_G0275715	NA
chr2	6033383	6033820	-	DDB_G0275513	DDB_G0275513	conserved in bacteria%2C plants and protozoans%3B contains two transmembrane domains
chr2	6034546	6037716	+	DDB_G0275917	DDB_G0275917	NA
chr2	6037798	6040206	-	DDB_G0275919	DDB_G0275919	NA
chr2	6040578	6041513	-	DDB_G0275713	DDB_G0275713	conserved hypothetical protein%3B contains a putative N-terminal signal sequence
chr2	6042281	6044641	-	DDB_G0275711	nhe1	required for cell polarity%3B mediates both K%3Csup%3E%2B%3C%2Fsup%3E facilitation of cell motility and K%3Csup%3E%2B%3C%2Fsup%3E%2FNa%3Csup%3E%2B%3C%2Fsup%3E requirement in chemotactic orientation%3B the genetic interaction between aip1 and nhe1 suggest that defective chemotaxis in nhe1- mutants may be determined by loss of cofilin-dependent actin dynamics
chr2	6045706	6050557	+	DDB_G0275635	pik6	phosphatidylinositol phosphate kinase that binds diacylglycerol%3B essential for normal early developmental gene expression
chr2	6051213	6053156	+	DDB_G0275515	asnB	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B L-glutamine %2B L-aspartate %2B ATP -%3E L-glutamate %2B L-asparagine %2B pyrophosphate %2B AMP
chr2	6053556	6054109	-	DDB_G0275709	DDB_G0275709_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0275921%22%3EDDB_G0275921%3C%2Fa%3E 
chr2	6054662	6055659	-	DDB_G0275921	DDB_G0275921	NA
chr2	6056870	6058918	-	DDB_G0275637	abcF3	consists of two ABC domains and lacks a transmembrane domain
chr2	6059162	6059755	-	DDB_G0275923	DDB_G0275923	similar to Streptococcus pneumoniae AcpS %3B transfers the 4%27-phosphopantetheine moiety from coenzyme A to a serine residue specifically of stand-alone acyl carrier proteins
chr2	6059895	6061338	+	DDB_G0275517	gtf2h3	general transcription factor required for the initiation of transcription by RNA polymerase II
chr2	6062122	6063145	+	DDB_G0275519	DDB_G0275519	NA
chr2	6064231	6065776	+	DDB_G0275925	wdr68	NA
chr2	6066450	6067981	+	DDB_G0275521	DDB_G0275521	NA
chr2	6068094	6070766	-	DDB_G0275523	DDB_G0275523	NA
chr2	6071471	6073759	-	DDB_G0275927	DDB_G0275927	NA
chr2	6074432	6078862	+	DDB_G0275929	pds5	%3Cb%3ECommunity annotation:%3C%2Fb%3E  similar to pds5%2C which interacts with the chromosomal cohesion complex and modulates the cohesion of chromosomes and kinetochores in ways that are only now being explored (%3Ca target %3D %22new%22 href%3D%22http:%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F16819604%22%3Esee Dorsett 2007%3C%2Fa%3E).  Pds5 is related to nipped-B%2C for which Dicty also has a probable homolog (%3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0283099%22%3EDDB_G0283099%3C%2Fa%3E).   The role of pds5 in Dicty cell cycle control is supported by its sixfold overexpression in a Dicty strain lacking the  retinoblastoma like gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E (Doquang et al%2C in preparation).   Most genes involved in DNA synthesis and mitosis are overexpressed in this strain.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E  
chr2	6080040	6080307	+	DDB_G0275639	DDB_G0275639	NA
chr2	6081078	6081314	+	DDB_G0275477	DDB_G0275477	NA
chr2	6082396	6082628	+	DDB_G0275641	DDB_G0275641	NA
chr2	6082948	6086502	+	DDB_G0275707	DDB_G0275707	weakly similar to ints10%2C component of a multiprotein mediator of small nuclear RNA processing
chr2	6086909	6087949	+	DDB_G0275475	DDB_G0275475	NA
chr2	6088223	6089011	-	DDB_G0275931	ncsA	contains four EF-hands%3B belongs to the frequenins%2C a family of myristoyl-switch calcium-binding proteins
chr2	6089719	6090352	-	DDB_G0275473	rps24	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S24 homolog
chr2	6090814	6091381	+	DDB_G0275933	DDB_G0275933	homolog of S. cerevisiae CMC1 (COX assembly mitochondrial protein)%2C which is a copper-binding protein required for mitochondrial cytochrome c oxidase assembly
chr2	6092208	6093026	-	DDB_G0275617	tbpA	general transcription factor that binds to the TATA-box promoter element%3B component of the transcription factor TFIIIB%2C shown to bind to subunits brf1 and weakly to bdp1%3B interacts with the non LTR retrotransposons TRE5-A and TRE5-B
chr2	6094205	6095171	-	DDB_G0275471	csn8	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8) 
chr2	6095467	6096386	-	DDB_G0275935	DDB_G0275935	NA
chr2	6096697	6098313	-	DDB_G0275469	DDB_G0275469	similar to endonuclease V%2C which catalyses the endonucleolytic cleavage of apurinic or apyrimidinic sites to generate products with a 5%27-phosphate 
chr2	6099175	6102987	+	DDB_G0275937	DDB_G0275937	NA
chr2	6103616	6106499	+	DDB_G0275453	abcA11	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr2	6106886	6107851	-	DDB_G0275619	pppB	NA
chr2	6110111	6111847	-	DDB_G0275455	srp54	component of the signal recognition particle (SRP)%2C which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulum
chr2	6112474	6113253	+	DDB_G0275457	DDB_G0275457	NA
chr2	6113524	6114624	+	DDB_G0275459	DDB_G0275459	NA
chr2	6115320	6115946	-	DDB_G0275461	DDB_G0275461_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0275465%22%3EDDB_G0275465%3C%2Fa%3E
chr2	6116744	6116992	+	DDB_G0275463	DDB_G0275463	NA
chr2	6117739	6119131	-	DDB_G0275465	DDB_G0275465_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0272823%22%3EDDB_G0272823%3C%2Fa%3E 
chr2	6119794	6121989	-	DDB_G0275467	DDB_G0275467	catalyzes the reaction a 5%27-ribonucleotide %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E a ribonucleoside %2B phosphate
chr2	6122802	6122871	+	DDB_G0295517	sno17	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr2	6123589	6125651	+	DDB_G0275939	mbtps2	ortholog of H. sapiens MBTPS2%2C which catalyzes the proteolytic activation of sterol regulatory element-binding proteins (SREBPs)
chr2	6126263	6126516	+	DDB_G0275705	DDB_G0275705	NA
chr2	6127229	6127302	+	DDB_G0294861	tRNA-Val-AAC-7	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6128275	6128749	+	DDB_G0275941	DDB_G0275941_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr2	6128899	6131523	+	DDB_G0275943	DDB_G0275943_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr2	6132328	6132399	+	DDB_G0294863	tRNA-Asp-GUC-8	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr2	6133220	6133861	+	DDB_G0275945	DDB_G0275945_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	6134212	6137140	+	DDB_G0275947	DDB_G0275947_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2	6139718	6140764	-	DDB_G0275991	DDB_G0275991	NA
chr2	6141360	6142663	+	DDB_G0275989	DDB_G0275989	NA
chr2	6143298	6144350	+	DDB_G0275987	DDB_G0275987	NA
chr2	6144623	6145813	-	DDB_G0275985	mcfH	ortholog of SLC25a40%2C that belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr2	6146641	6148346	+	DDB_G0275983	cdc6	%3Cb%3ECommunity annotation:%3C%2Fb%3E ortholog of cdc6%2C long known to be a critical member of the DNA pre-replication complex%2C  and more recently implicated in control of mitosis  (see %3Ca href%3D%22http:%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F18256547%22%3EBoronat and Campbell%2C 2008%3C%2Fa%3E).  The role of cdc6 in Dicty cell cycle progression is supported by its eightfold  overexpression in a Dicty strain lacking the retinoblastoma-like gene%2C  %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E (Doquang et al%2C in preparation).   (Doquang et al%2C in preparation). Most genes involved in DNA replication and mitosis  are overexpressed in this strain.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E
chr2	6148751	6150499	+	DDB_G0275981	DDB_G0275981	contains no functional domains and is not similar to any other protein
chr2	6150629	6151464	-	DDB_G0275993	DDB_G0275993	NA
chr2	6151550	6153237	+	DDB_G0275979	thoc7	ortholog of THOC7%2C which exists in the THO complex required for transcriptional elongation
chr2	6155469	6155723	+	DDB_G0275977	lvsB_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271504%22%3E%3Ci%3ElvsB%3C%2Fi%3E%3C%2Fa%3E
chr2	6156043	6156789	-	DDB_G0275995	DDB_G0275995_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0275997%22%3EDDB_G0275997%3C%2Fa%3E
chr2	6157246	6158193	-	DDB_G0275997	DDB_G0275997	NA
chr2	6158412	6161199	-	DDB_G0275999	msh1	similar to bacterial mismatch repair protein MutS%3B putative mitochondrial mismatch repair protein
chr2	6162014	6162087	-	DDB_G0294949	tRNA-Val-AAC-10	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6162439	6162700	-	DDB_G0276001	DDB_G0276001	NA
chr2	6164176	6164778	+	DDB_G0276003	hspG2	NA
chr2	6165066	6165403	-	DDB_G0275975	DDB_G0275975	related to the hssA genes
chr2	6165936	6171999	-	DDB_G0276005	DDB_G0276005	NA
chr2	6173352	6174300	+	DDB_G0275973	DDB_G0275973	NA
chr2	6175233	6177610	+	DDB_G0275971	DDB_G0275971	contains one RRM (RNA recognition motif) domain
chr2	6178436	6179411	+	DDB_G0276007	DDB_G0276007	NA
chr2	6179943	6180801	+	DDB_G0275969	rab1E	similar to rab1
chr2	6182669	6184438	+	DDB_G0276009	DDB_G0276009_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr2	6185531	6186865	-	DDB_G0276011	DDB_G0276011_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	6187314	6187386	+	DDB_G0294865	tRNA-Arg-UCU-3	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6187951	6190250	-	DDB_G0275967	DDB_G0275967	belongs to the amidase family
chr2	6191275	6193613	-	DDB_G0276013	DDB_G0276013	contains an N-terminal F-box domain and eight ankyrin repeats
chr2	6195575	6197240	-	DDB_G0276015	DDB_G0276015	NA
chr2	6197621	6200891	-	DDB_G0275957	sf3b1	subunit of the splicing factor SF3B required for spliceosome assembly
chr2	6201276	6202685	+	DDB_G0276017	DDB_G0276017	NA
chr2	6203910	6208439	+	DDB_G0276019	gefY	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form%3B similar to son of sevenless
chr2	6208676	6209272	-	DDB_G0275955	rabH	NA
chr2	6210610	6211824	-	DDB_G0275953	DDB_G0275953	sulfurates the molybdenum cofactor%2C which is essential for xanthine dehydrogenase and aldehyde oxidase
chr2	6212260	6213133	-	DDB_G0294579	rab_ps1	putative pseudogene%3B similar to Rab GTPase family proteins
chr2	6213523	6213857	+	DDB_G0275965	DDB_G0275965	NA
chr2	6214903	6215784	+	DDB_G0275959	DDB_G0275959	some members of this family have guanine nucleotide exchange activity
chr2	6216012	6217418	-	DDB_G0275963	DDB_G0275963	NA
chr2	6217776	6219062	-	DDB_G0275961	DDB_G0275961	NA
chr2	6219625	6219938	-	DDB_G0276021	DDB_G0276021	NA
chr2	6220039	6222009	-	DDB_G0276265	DDB_G0276265	NA
chr2	6222654	6225612	+	DDB_G0276227	DDB_G0276227	NA
chr2	6225937	6226160	-	DDB_G0276161	DDB_G0276161	NA
chr2	6226640	6227035	-	DDB_G0276139	DDB_G0276139	NA
chr2	6227029	6227101	-	DDB_G0294947	tRNA-Arg-UCU-6	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6228081	6230874	+	DDB_G0276229	clcC	CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles%3B they assemble to form homo-dimers
chr2	6232165	6232410	+	DDB_G0276231	DDB_G0276231	NA
chr2	6232603	6238286	-	DDB_G0276137	xrn1	ortholog of H. sapiens XRN1 and S. cerevisiae KEM1 (Kar-Enhancing Mutations 1) involved in RNA metabolism
chr2	6238985	6239999	+	DDB_G0276135	DDB_G0276135	NA
chr2	6240850	6242918	+	DDB_G0276133	DDB_G0276133	NA
chr2	6243302	6244505	+	DDB_G0276131	DDB_G0276131	contains no functional domains
chr2	6244624	6246005	-	DDB_G0276129	cdc123	ortholog of S. cerevisiae cdc123%2C involved in the nutritional control of the cell cycle
chr2	6247229	6247741	+	DDB_G0276127	DDB_G0276127	NA
chr2	6247906	6248356	-	DDB_G0276225	DDB_G0276225	similar to yeast ERG28%2C an endoplasmic reticulum protein involved in ergosterol biosynthesis%3B contains 4 putative transmembrane domains
chr2	6248649	6252929	-	DDB_G0276125	DDB_G0276125	NA
chr2	6255698	6255964	+	DDB_G0276123	DDB_G0276123	NA
chr2	6256669	6258810	+	DDB_G0276121	DDB_G0276121	NA
chr2	6259472	6262432	+	DDB_G0276119	cnrF	calcium-regulated Rab11a Rab GAP that forms a complex with p2xA and rab11a%3B involved in osmoregulation and vesicle fusion to the membrane%3B identified as a suppressor of smlA null mutant cnr6 
chr2	6262508	6263184	-	DDB_G0276117	DDB_G0276117	NA
chr2	6263547	6265732	+	DDB_G0276223	DDB_G0276223	NA
chr2	6265977	6267838	-	DDB_G0276233	cct8	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr2	6268498	6269319	+	DDB_G0276115	dph5	ortholog to the conserved DPH5%2C a methyltransferase which in %3Ci%3ES. cerevisiae%3C%2Fi%3E is required for synthesis of diphthamide%2C a modified histidine residue of translation elongation factor 2
chr2	6269416	6270217	-	DDB_G0276113	DDB_G0276113	NA
chr2	6270826	6272073	+	DDB_G0276111	DDB_G0276111	NA
chr2	6272283	6273958	-	DDB_G0276109	nup53	ortholog of the conserved NUP53 protein%3B localizes to the nuclear envelope (pers. communication: P. Batsios %26 R. Graef)
chr2	6274208	6275509	-	DDB_G0276159	rtc1	ortholog of RTC1 which catalyzes the conversion of 3%27-phosphate to a 2%27%2C3%27-cyclic phosphodiester at the end of RNA
chr2	6275918	6280963	-	DDB_G0276157	pkgA	serine%2Fthreonine protein kinase of the MAST (Microtubule Associated Serine%2FThreonine kinase) family
chr2	6281262	6281930	-	DDB_G0276235	DDB_G0276235	NA
chr2	6284187	6287507	-	DDB_G0276155	spnA	gene essential for Dictyostelium development with an N-terminal Galpha regulatory domain and a C-terminal PP2C serine%2Fthreonine phosphatase domain
chr2	6288449	6290700	-	DDB_G0276107	DDB_G0276107	NA
chr2	6292325	6299746	+	DDB_G0276105	gtr2	distant relative of CAZy family GT5%3B contains a glycosyltransferase domain and an alpha amylase catalytic domain
chr2	6301145	6305656	+	DDB_G0276103	enlA	N-terminal similarity to talin%2C C-terminal similarity to fimbrins%3B actin binding protein%2C plays a role in cytokinesis and substrate adhesion%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E This gene has been erroneously referred to as %3Ca href%3D%22 %2Fgene%2FDDB_G0289313%22%3EfmrC%3C%2Fa%3E in reference %3Ca href%3D%22%2Fpublication%2Fpubmed%2F18349074%22%3EPMID:18349074%3C%2Fa%3E
chr2	6306373	6307707	+	DDB_G0276237	DDB_G0276237	similar to PRMT proteins (protein arginine methyltransferase)
chr2	6307785	6312539	-	DDB_G0276221	fam21	NA
chr2	6313321	6316891	-	DDB_G0276027	pdeE	NA
chr2	6318754	6321098	+	DDB_G0276153	nsfA	ATPase required for endocytosis%2C membrane trafficking and cell motility%3B acts as a SNAP receptor (SNARE) chaperone which binds%2C through soluble NSF attachment proteins (SNAPs)%2C to SNARE complexes and utilizes the energy of ATP hydrolysis to promote SNARE recycling
chr2	6321257	6325878	-	DDB_G0276101	smc3	functions in chromosome dynamics%3B heterodimerizes with smc1
chr2	6326680	6327810	+	DDB_G0276099	DDB_G0276099	contains no functional domains and is not similar to any other protein
chr2	6328288	6330094	+	DDB_G0276097	DDB_G0276097	contains two transmembrane domains
chr2	6331145	6332882	+	DDB_G0276219	DDB_G0276219	contains one transmembrane domain
chr2	6333535	6335278	+	DDB_G0276095	DDB_G0276095	NA
chr2	6335483	6335752	-	DDB_G0276217	DDB_G0276217	NA
chr2	6339087	6341662	+	DDB_G0276093	DDB_G0276093	NA
chr2	6342811	6345129	+	DDB_G0276215	DDB_G0276215	similar to bacterial glycosyl hydrolases
chr2	6345319	6349860	-	DDB_G0276091	cldB	NA
chr2	6350255	6355144	-	DDB_G0276089	DDB_G0276089	NA
chr2	6356046	6357723	+	DDB_G0276213	DDB_G0276213	NA
chr2	6358797	6360131	+	DDB_G0276087	DDB_G0276087	NA
chr2	6360342	6362780	+	DDB_G0276085	DDB_G0276085	NA
chr2	6363456	6364367	-	DDB_G0276211	DDB_G0276211_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr2	6364519	6364591	-	DDB_G0294945	tRNA-Gln-UUG-8	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6365054	6366388	+	DDB_G0276209	DDB_G0276209_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	6367655	6371215	+	DDB_G0276207	iliL_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0281853%22%3E%3Ci%3EiliL%3C%2Fi%3E%3C%2Fa%3E 
chr2	6371487	6372986	-	DDB_G0276205	DDB_G0276205	related to vacuolar sorting proteins VPS45 and VPS33
chr2	6373737	6376313	-	DDB_G0276239	DDB_G0276239	involved in vesicle-mediated transport%3B similar to VPS33 
chr2	6376612	6377823	-	DDB_G0276203	DDB_G0276203	NA
chr2	6378549	6378998	-	DDB_G0276201	DDB_G0276201_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	6379305	6379386	+	DDB_G0294867	tRNA-Ser-AGA-3	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6380617	6384051	-	DDB_G0276197	DDB_G0276197_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	6384158	6385522	-	DDB_G0276195	DDB_G0276195_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	6386977	6387050	+	DDB_G0294869	tRNA-Arg-ACG-3	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6387804	6389572	-	DDB_G0276193	DDB_G0276193	contains repeats found in several Chlamydia polymorphic membrane proteins%3B has a signal peptide and a carboxy-terminus transmembrane domain
chr2	6390838	6392148	+	DDB_G0276189	DDB_G0276189	NA
chr2	6392232	6393047	-	DDB_G0276151	DDB_G0276151	belongs to the crotonase superfamily%3B conserved in bacteria%3B contains a predicted peroxisomal targeting signal
chr2	6393550	6396094	-	DDB_G0276025	zakA	contains two kinase domains%3B N-terminal kinase domain related to STE group%3B C-terminal domain similar to TKL group
chr2	6396810	6399048	-	DDB_G0276187	zak2	contains two kinase domains%3B N-terminal kinase domain related to STE group%3B C-terminal domain similar to TKL group%3B highly similar to zakA and has overlapping function with zakA%3B shown to be a tyrosine kinase and regulator of GSK3%3B also regulates pattern formation during development via dstC (STATc) signaling
chr2	6400232	6401363	+	DDB_G0276149	rliC	repressed after %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr2	6401716	6404742	-	DDB_G0276147	DDB_G0276147	NA
chr2	6408604	6409503	-	DDB_G0276183	DDB_G0276183	NA
chr2	6410071	6414915	-	DDB_G0276181	DDB_G0276181	member of the TKL (tyrosine kinase-like) group of protein kinases%3B contains a PH (pleckstrin homology) domain
chr2	6415536	6416900	+	DDB_G0276083	lip4	similar to the human lipase family%3B catalyzes the reaction: Triacylglycerol %2B H%3Csub%3E2%3C%2Fsub%3EO %3D diacylglycerol %2B a carboxylate
chr2	6417198	6417544	-	DDB_G0276241	atp5e	epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase%2C the enzyme complex responsible for ATP synthesis
chr2	6418177	6421294	+	DDB_G0276243	DDB_G0276243	contains one DUF1620 domain%3B homolog of human KIAA0090 (uncharacterized protein KIAA0090)%3B contains 2 putative transmembrane domains
chr2	6421444	6422214	-	DDB_G0276081	DDB_G0276081	NA
chr2	6422563	6424587	+	DDB_G0276079	mproS	catalyzes the reaction ATP %2B L-proline %2B tRNAPro %3D AMP %2B diphosphate %2B L-prolyl-tRNAPro
chr2	6426413	6427552	+	DDB_G0276077	mlcR	component of actin-based molecular motor%3B myosin II (conventional myosin) component
chr2	6427907	6428684	+	DDB_G0276179	DDB_G0276179	contains a predicted signal peptide%3B weakly similar to DDB_G0272504
chr2	6429266	6430461	+	DDB_G0276075	DDB_G0276075	NA
chr2	6430683	6432257	-	DDB_G0276073	recA	similar to recombinase A proteins found in bacteria and in A. thaliana%3B plays a role in DNA repair
chr2	6432588	6434179	-	DDB_G0305372	DDB_G0305372	NA
chr2	6435703	6443825	-	DDB_G0276029	DDB_G0276029	putative ortholog of H. sapiens CNOT1 and S. cerevisiae CDC39%3B REMI mutant forms aberrant fruiting bodies (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0276029%22%3Ecommunity annotation%3C%2Fa%3E) 
chr2	6445628	6448087	-	DDB_G0276069	hapA	HAP2-GCS1 is found from plants to lower eukaryotes and is necessary for the fusion of gametes in plants
chr2	6448691	6450078	+	DDB_G0276067	ddcB	similar to diaminopimelate decarboxylase%2C which catalyzes the reaction meso-2%2C6-diaminoheptanedioate %3D L-lysine %2B CO%3Csub%3E2%3C%2Fsub%3E
chr2	6450283	6452364	-	DDB_G0276065	DDB_G0276065	catalyzes the reaction acyl-CoA %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E trans-2%2C3-dehydroacyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr2	6452850	6453171	-	DDB_G0276063	DDB_G0276063	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon  
chr2	6454072	6456104	-	DDB_G0276245	DDB_G0276245	catalyzes the reaction acyl-CoA %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E trans-2%2C3-dehydroacyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr2	6456944	6459982	-	DDB_G0294633	DDB_G0294633	contains two ankyrin repeats%2C which are among the most common protein-protein interaction motifs
chr2	6461770	6463986	+	DDB_G0276031	DDB_G0276031	similar human THO complex subunit 3 (THOC3)%2C although D. discoideum seems to be lacking THOC4 and THOC5
chr2	6464158	6464660	-	DDB_G0276247	DDB_G0276247	contains no functional domains and is not similar to any other protein
chr2	6465016	6465426	-	DDB_G0276061	DDB_G0276061	NA
chr2	6466369	6466758	+	DDB_G0276173	DDB_G0276173	NA
chr2	6468555	6469229	+	DDB_G0276059	DDB_G0276059	NA
chr2	6469384	6471238	-	DDB_G0276057	DDB_G0276057	NA
chr2	6473009	6473086	+	DDB_G0294871	tRNA-Ser-UGA-5	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6476907	6480086	-	DDB_G0276171	DDB_G0276171_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6480611	6481690	-	DDB_G0276249	DDB_G0276249_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6482159	6482239	-	DDB_G0294943	tRNA-Leu-CAA-2	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6482785	6483466	-	DDB_G0276053	rabF2_ps	putative pseudogene%3B Rab family protein
chr2	6484404	6485465	+	DDB_G0276051	DDB_G0276051	NA
chr2	6485825	6485986	+	DDB_G0295519	rnu1e_ps	putative pseudogene%3B similar to U1 snRNA%2C a component of the spliceosome involved in pre-mRNA splicing
chr2	6486635	6488479	-	DDB_G0276049	DDB_G0276049	weakly similar to NLP%2FP60 domain-containing proteins%2C bacterial cell wall-associated hydrolases
chr2	6489001	6495946	-	DDB_G0276047	DDB_G0276047	NA
chr2	6496624	6497523	+	DDB_G0276045	DDB_G0276045	NA
chr2	6497773	6499261	+	DDB_G0276169	DDB_G0276169	similar to S. cerevisiae MSP1%2C a mitochondrial protein involved in sorting of proteins in the mitochondria
chr2	6500338	6504666	+	DDB_G0276251	DDB_G0276251	similar to H. sapiens GP17%2C involved in modification of glycosylphosphatidylinositol%3B  contains 16 transmembrane domains
chr2	6504888	6507143	-	DDB_G0276253	DDB_G0276253	a bifunctional enzyme that catalyses both the synthesis and the degradation of fructose-2%2C 6-bisphosphate
chr2	6507776	6510379	-	DDB_G0276255	DDB_G0276255	NA
chr2	6510818	6516003	-	DDB_G0276043	ifkC	putative eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase%3B putative protein serine%2Fthreonine kinase%3B contains the RWD domain found in GCN2 kinases and histidyl tRNA synthetases%3B related to the GCN2 family of protein kinases that phosphorylate the alpha subunit of eIF2
chr2	6516957	6518404	-	DDB_G0276167	DDB_G0276167	NA
chr2	6519312	6521033	+	DDB_G0276041	tmem184B	TMEM184 family protein%2C similar to H. sapiens TMEM184A%2C B%2C C%3B contains 6 predicted transmembrane domains
chr2	6521223	6522277	-	DDB_G0276039	DDB_G0276039	NA
chr2	6522877	6523652	+	DDB_G0276145	DDB_G0276145	NA
chr2	6523775	6527403	-	DDB_G0276143	dhkF	NA
chr2	6527471	6528715	-	DDB_G0276257	DDB_G0276257	NA
chr2	6529676	6531372	-	DDB_G0276259	DDB_G0276259	contains 5 predicted transmembrane domains and an additional putative signal sequence%3B similar to D. purpureum protein
chr2	6532428	6534156	-	DDB_G0276261	mcfV	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr2	6536235	6538520	+	DDB_G0276263	DDB_G0276263	NA
chr2	6539160	6540179	+	DDB_G0276037	DDB_G0276037	NA
chr2	6540411	6540664	-	DDB_G0276165	DDB_G0276165	expressed in prespore cells
chr2	6541243	6545899	-	DDB_G0276035	DDB_G0276035	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr2	6548168	6549349	+	DDB_G0276141	pdi1	catalyzes the rearrangement of disulfide bonds in proteins 
chr2	6550267	6550782	+	DDB_G0276033	cyb5A	cytochrome b5 is a membrane bound hemoprotein that functions as an electron carrier for several membrane bound oxygenases%3B contains a single C-terminal transmembrane domain
chr2	6552432	6555025	-	DDB_G0276315	DDB_G0276315	NA
chr2	6556293	6557348	+	DDB_G0276297	DDB_G0276297	NA
chr2	6558113	6558769	+	DDB_G0276295	rabW	NA
chr2	6559102	6560574	-	DDB_G0276293	DDB_G0276293	contains eight transmembrane domains
chr2	6561863	6563973	+	DDB_G0276317	DDB_G0276317	NA
chr2	6564892	6565379	+	DDB_G0276291	DDB_G0276291	NA
chr2	6565732	6566716	-	DDB_G0276319	fam18A	similar to a conserved protein of unknown function found associated with the v-SNARE Tlg2p in the membrane of late Golgi vesicles in S. cerevisiae
chr2	6567409	6569592	-	DDB_G0276321	DDB_G0276321	similar to mammalian SA hypertension-associated homolog and to acetoacetyl-CoA synthetases%2C which catalyze the first step of the mevalonate pathway of isoprenoid biosynthesis via isopentenyl diphosphate
chr2	6570030	6570521	-	DDB_G0276289	DDB_G0276289	NA
chr2	6571351	6571432	+	DDB_G0294873	tRNA-Ser-AGA-4	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6571874	6572953	+	DDB_G0276323	DDB_G0276323_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6573478	6576657	+	DDB_G0276313	DDB_G0276313_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6577116	6578232	-	DDB_G0276287	expl3	similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B contains a predicted signal peptide%3B expressed in prespore cells
chr2	6579134	6582276	-	DDB_G0276299	agnA	NA
chr2	6582943	6592973	-	DDB_G0276269	sgcA	homolog of mammalian soluble adenylyl cyclase
chr2	6594215	6596199	+	DDB_G0276285	DDB_G0276285	NA
chr2	6597404	6599572	+	DDB_G0276309	DDB_G0276309	NA
chr2	6600384	6603408	+	DDB_G0276283	utp13	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA%3B highly similar to H. sapiens transducin beta-like 3 (TBL3)
chr2	6603655	6608085	-	DDB_G0276307	DDB_G0276307	NA
chr2	6608304	6609335	-	DDB_G0276281	DDB_G0276281	NA
chr2	6610188	6611499	+	DDB_G0276279	DDB_G0276279	NA
chr2	6612090	6614240	+	DDB_G0276305	DDB_G0276305	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr2	6614400	6618895	-	DDB_G0276303	DDB_G0276303	contains weak similarity to EGF-like domain%3B contains both a predicted N-terminal signal sequence and C-terminal transmembrane domain
chr2	6619603	6620779	-	DDB_G0276267	gpaB	subunit of the heterotrimeric G protein that has GTPase activity%3B involved in the chemotactic response to cAMP
chr2	6627741	6628430	+	DDB_G0276277	DDB_G0276277	NA
chr2	6628998	6629732	+	DDB_G0276275	DDB_G0276275	NA
chr2	6631152	6632576	+	DDB_G0276273	H2Bv2	NA
chr2	6633638	6636947	+	DDB_G0276325	DDB_G0276325	NA
chr2	6637140	6638780	-	DDB_G0276271	DDB_G0276271	NA
chr2	6639378	6639755	-	DDB_G0276327	DDB_G0276327	NA
chr2	6640387	6640459	+	DDB_G0294875	tRNA-Arg-UCU-4	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6641376	6641623	+	DDB_G0276329	DDB_G0276329_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6642428	6645493	+	DDB_G0276387	DDB_G0276387_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6646491	6646573	-	DDB_G0294941	tRNA-Leu-UAA-5	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6647152	6647224	-	DDB_G0294939	tRNA-Arg-UCU-5	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6648064	6651339	+	DDB_G0276369	kif5	kinesin-1 family protein%2C belongs to the kinesin KHC subfamily%3B binds microtubules in an ATP-dependent manner and bundles actin in vitro
chr2	6651958	6655821	+	DDB_G0276389	DDB_G0276389	NA
chr2	6655928	6658354	-	DDB_G0276353	torA	required for chemotaxis%3B largely alpha-helical protein with a predicted C-terminal coiled-coil domain%3Cbr%2F%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with tor%2C the ortholog of target of rapamycin gene 
chr2	6659047	6661094	+	DDB_G0276337	DDB_G0276337	NA
chr2	6661296	6662457	-	DDB_G0276339	DDB_G0276339_ps	putative pseudogene%2C similar to %3Ca href%3D%22DDB_G0286157%22%3EDDB_G0286157%3C%2Fa%3E%2C %3Ca href%3D%22DDB_G0272288%22%3EDDB_G0272288%3C%2Fa%3E
chr2	6663471	6665132	-	DDB_G0276341	pccB	catalyzes the reaction ATP %2B HCO3%3Csup%3E-%3C%2Fsup%3E %2B propionyl-CoA %3C%3D%3E ADP %2B phosphate %2B D-methylmalonyl-CoA
chr2	6666022	6667542	+	DDB_G0276391	DDB_G0276391_ps	putative pseudogene%3B EGF family protein
chr2	6669753	6670914	+	DDB_G0276343	gpaK	NA
chr2	6671139	6675100	-	DDB_G0276375	DDB_G0276375	contains ten putative transmembrane domains
chr2	6676259	6679209	-	DDB_G0276377	anapc2	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr2	6679320	6680012	+	DDB_G0276345	naa20	ortholog of the conserved catalytic subunit of the NatB N-terminal acetyltransferase (NAA20)%2C which in yeast catalyzes the transfer of an acetyl group to the N-terminal residue of a protein that contains a Met-Glu%2C Met-Asp%2C Met-Asn%2C or Met-Met N-terminus
chr2	6680526	6680615	-	DDB_G0294937	tRNA-Thr-UGU-2	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6681538	6695830	-	DDB_G0276355	dhcA	microtubule-dependent mechanochemical enzyme
chr2	6697417	6698490	+	DDB_G0276347	DDB_G0276347	NA
chr2	6698814	6702834	+	DDB_G0276349	fnkC	contains a meprin and TRAF homology (MATH) domain and five Dictyostelium-specific FNIP repeats%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr2	6703448	6704140	+	DDB_G0276351	DDB_G0276351	similar to bacterial glutathione S-transferase%3B catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione
chr2	6705104	6705176	-	DDB_G0294935	tRNA-Gln-UUG-7	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6705904	6706141	-	DDB_G0276379	DDB_G0276379	NA
chr2	6706766	6713836	-	DDB_G0276371	gefL	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr2	6717804	6719262	-	DDB_G0276333	tipB	involved in early development and tip formation
chr2	6720252	6721431	+	DDB_G0276357	gemin1	putative ortholog of Gemin 1%2FSNM1 (Survival of motor neuron protein 1)%2C a component of Cajal bodies (CBs) and Gems%2C nuclear organelles responsible for spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis
chr2	6722202	6722989	+	DDB_G0276381	DDB_G0276381	NA
chr2	6724130	6724203	-	DDB_G0294933	tRNA-Arg-ACG-6	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6724904	6726110	+	DDB_G0276393	DDB_G0276393	NA
chr2	6726246	6727358	-	DDB_G0276331	pyr4	catalyzes the reaction O%3Csub%3E2%3C%2Fsub%3E %2B dihydroorotate %3D H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E %2B orotate in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine ribonucleotides
chr2	6728694	6735498	+	DDB_G0276335	pyr1-3	multifunctional enzyme that carries out the three first enzymatic activities of the %3Ci%3Ede novo%3C%2Fi%3E pyrimidine biosynthetic pathway%3B very similar to the tri-functional human CAD enzyme
chr2	6735925	6742325	+	DDB_G0276383	DDB_G0276383	contains one von Willebrand factor type A domain
chr2	6742578	6743421	-	DDB_G0276359	sec11	ortholog of the conserved SEC11%3B the signal peptidase complex is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum%3B contains two putative transmembrane domains
chr2	6745195	6747564	+	DDB_G0276361	DDB_G0276361	NA
chr2	6748878	6759543	+	DDB_G0276363	myoG	required for cell polarity and chemotaxis to cAMP%3B plays a role in mediating early chemotactic signalling%3B contains an N-terminal motor domain%2C two MyTH4 domains%2C an IQ calmodulin-binding region%2C and a SH3 domain
chr2	6760197	6761306	+	DDB_G0276365	DDB_G0276365	has similarity to H. sapiens di-N-acetylchitobiase (CBTS)%2C a hydrolase involved in the degradation of asparagine-linked glycoproteins%3B contains a putative N-terminal signal sequence
chr2	6761550	6762644	+	DDB_G0276367	DDB_G0276367	NA
chr2	6763233	6765975	+	DDB_G0276395	acapB	similar to mammalian Acap3%3B hydrolyzes GTP bound to ArfA in vitro
chr2	6766972	6767045	+	DDB_G0294877	tRNA-Phe-GAA-5	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6767487	6768498	+	DDB_G0276397	DDB_G0276397_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6769215	6769970	-	DDB_G0276525	DDB_G0276525_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6771543	6771613	-	DDB_G0294931	tRNA-Pro-UGG-9	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr2	6771686	6771759	-	DDB_G0294929	tRNA-Phe-GAA-7	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6772155	6777982	-	DDB_G0276527	DDB_G0276527	contains 3 major domains: one RCC1 domain%2C one protein kinase domain%2C and one HECT domain%3B N-terminal region beongs to the Ser%2FThr protein kinase family%3B C-terminal region belongs to the CAMK Ser%2FThr protein kinase family.
chr2	6778627	6780280	+	DDB_G0276481	ercc8	ortholog of %3Ci%3ES. cerevisiae%3C%2Fi%3E RAD26 and  %3Ci%3EH. sapiens%3C%2Fi%3E ERCC8 (CSA)%2C involved in Cockayne syndrome
chr2	6780883	6787558	+	DDB_G0276529	DDB_G0276529	NA
chr2	6787819	6788781	-	DDB_G0276483	DDB_G0276483	NA
chr2	6789174	6792248	+	DDB_G0276401	DDB_G0276401	NA
chr2	6792443	6795412	-	DDB_G0276453	vilB	belongs to the villin%2Fgelsolin family%3B contains 6 gelsolin-like repeats and a villin headpiece domain
chr2	6795915	6798857	-	DDB_G0276531	DDB_G0276531	similar to elaC and TRZ%2C a zinc phosphodiesterase with tRNA 3%27-processing endonuclease activity and probably involved in tRNA maturation by removing a 3%27-trailer from precursor tRNA%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  similar to elaC%2C an endoribonuclease conserved from bacteria to humans%2C sequence variants of which are associated with aggressive prostate cancer. Nothing seems to be known about the connection between elaC and cell proliferation. The possible involvement of the Dicty gene in cell cycle control is suggested by its 3%2C4-fold overexpression in a Dicty strain lacking the  retinoblastoma like gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E (Doquang et al%2C in preparation).   Most genes involved in DNA synthesis and mitosis are overexpressed in this strain.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr2	6800222	6801839	-	DDB_G0276455	gpaG	NA
chr2	6804850	6805473	-	DDB_G0276533	DDB_G0276533	NA
chr2	6806163	6807386	-	DDB_G0276535	DDB_G0276535	NA
chr2	6807798	6808245	+	DDB_G0276537	DDB_G0276537	NA
chr2	6809160	6809552	+	DDB_G0276457	rps15a	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S15a homolog
chr2	6809778	6811185	-	DDB_G0276485	DDB_G0276485	conserved in Dictyostelids and in metazoans like Nematostella and Ciona
chr2	6811793	6814590	+	DDB_G0276539	DDB_G0276539_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276559%22%3EDDB_G0276559%3C%2Fa%3E
chr2	6815001	6818129	+	DDB_G0276403	DDB_G0276403	NA
chr2	6818286	6819040	-	DDB_G0276405	pfp1	putative cysteine protease%3B member of the DJ-1%2FThiJ%2FPfpI family%2C which includes human PARK7 associated with Parkinson%27s disease
chr2	6819663	6825311	-	DDB_G0276541	DDB_G0276541	contains at least 11 transmembrane domains
chr2	6826555	6829323	+	DDB_G0276543	DDB_G0276543	NA
chr2	6829983	6831106	-	DDB_G0276545	DDB_G0276545	NA
chr2	6832640	6834224	+	DDB_G0276407	DDB_G0276407	NA
chr2	6834384	6837590	-	DDB_G0276409	DDB_G0276409_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276559%22%3EDDB_G0276559%3C%2Fa%3E
chr2	6839123	6843367	-	DDB_G0276547	DDB_G0276547_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276559%22%3EDDB_G0276559%3C%2Fa%3E
chr2	6843825	6846333	+	DDB_G0276413	DDB_G0276413	conserved protein%3B ortholog or HEATR3 (HEAT repeat containing 3)
chr2	6846542	6847303	-	DDB_G0276411	mrt4	involved in mRNA turnover and ribosome assembly
chr2	6847900	6850674	-	DDB_G0276459	pakB	protein serine%2Fthreonine kinase that phosphorylates myoD (myosin ID) and myoK (myosin IK) heavy chains%3B similar to p21-activated kinase%3B  belongs to the STE20 family%2C PAKA subfamily of protein kinases
chr2	6853485	6854897	-	DDB_G0276489	DDB_G0276489	contains 1 RING-type zinc finger%3B contains one putative transmembrane domain%3B similar to human ZFPL1 (zinc finger protein-like 1)
chr2	6855520	6856461	+	DDB_G0276491	mettl1	ortholog of the conserved methyltransferase-like 1 (METTL1) which in H. sapiens forms a complex with WDR4%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
chr2	6856691	6857573	-	DDB_G0276493	eIF6	prevents 60S and 40S ribosomal subunits to form the 80S ribosome by binding to the 60S subunit%3B in %3Ci%3EDictyosteliium%3C%2Fi%3E%2C nutrition uptake stimulates gene expression
chr2	6863248	6863320	-	DDB_G0294927	tRNA-Lys-UUU-7	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6863657	6864217	+	DDB_G0276495	DDB_G0276495_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	6865567	6866037	-	DDB_G0276497	DDB_G0276497	NA
chr2	6867377	6870420	+	DDB_G0276549	DDB_G0276549	NA
chr2	6871013	6871507	-	DDB_G0276419	DDB_G0276419	NA
chr2	6872132	6874474	+	DDB_G0276551	DDB_G0276551	protein family conserved in protozoans%2C fungi%2C and invertebrate animals
chr2	6875533	6878320	+	DDB_G0276553	DDB_G0276553	contains 5 coiled coil domains
chr2	6878753	6879364	-	DDB_G0276399	rab8B	NA
chr2	6881042	6881256	+	DDB_G0276421	DDB_G0276421	NA
chr2	6881531	6885323	-	DDB_G0276423	hira	ortholog of yeast HIR1%2C a transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A%2C H2B%2C H3 and H4 genes
chr2	6885788	6888462	+	DDB_G0276555	DDB_G0276555	NA
chr2	6888601	6890166	-	DDB_G0276417	pdhB	catalyzes the reaction lipoamide %2B pyruvate %3C%3D%3E S-acetyldihydrolipoamide %2B CO%3Csub%3E2%3C%2Fsub%3E%3B E1 beta component of pyruvate dehydrogenase complex%2C which contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0292994%22%3E phdA%3C%2Fa%3E%2C phdB)%2C dihydrolipoamide acetyltransferase (E2%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0277847%22%3E phdC%3C%2Fa%3E) and lipoamide dehydrogenase (E3%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0291648%22%3E lpd)%3C%2Fa%3E.
chr2	6891141	6891920	+	DDB_G0276415	rps18	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S18 homolog
chr2	6893167	6893438	+	DDB_G0276499	DDB_G0276499	NA
chr2	6893904	6894366	+	DDB_G0276501	DDB_G0276501_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276559%22%3EDDB_G0276559%3C%2Fa%3E
chr2	6896381	6897085	+	DDB_G0276557	DDB_G0276557	NA
chr2	6897934	6902781	+	DDB_G0276559	DDB_G0276559	NA
chr2	6903295	6903895	+	DDB_G0276425	nutf2	involved in protein transport into the nucleus%3B known to bind Ran in yeast and Arabidopsis
chr2	6904331	6906829	-	DDB_G0276461	DDB_G0276461	putative protein serine%2Fthreonine kinase%3B similar to the kinase domains of AAK1 (AP2 associated kinase) and BMP-inducible protein kinase (BIKe)
chr2	6907430	6908248	+	DDB_G0295773	DDB_G0295773	similar to the eukaryotic transmembrane protein 85 (TMEM85)%3B contains two putative transmembrane domains
chr2	6908594	6910052	+	DDB_G0276503	DDB_G0276503	very similar to the H. sapiens PISD%2C a mitochondrial proenzyme that is cleaved into a phosphatidylserine decarboxylase alpha and beta chain%3B contains one putative transmembrane domain
chr2	6910190	6912323	-	DDB_G0276437	DDB_G0276437	NA
chr2	6912714	6914186	-	DDB_G0349488	DDB_G0349488	NA
chr2	6914688	6915393	-	DDB_G0349487	DDB_G0349487	NA
chr2	6915740	6918993	-	DDB_G0276463	DG1112	NA
chr2	6919395	6920681	-	DDB_G0276435	DDB_G0276435	NA
chr2	6921413	6921651	+	DDB_G0276433	DDB_G0276433	NA
chr2	6923091	6923330	+	DDB_G0276505	DDB_G0276505	NA
chr2	6925108	6925342	+	DDB_G0276507	DDB_G0276507	NA
chr2	6927901	6928681	+	DDB_G0276479	ctnC	similar to countin (CtnA)
chr2	6929458	6930263	-	DDB_G0276563	DDB_G0276563	NA
chr2	6930950	6932392	+	DDB_G0276431	DDB_G0276431	NA
chr2	6932540	6934286	-	DDB_G0276429	DDB_G0276429	NA
chr2	6935162	6936262	+	DDB_G0276509	DDB_G0276509	NA
chr2	6936608	6938022	-	DDB_G0276427	osbF	NA
chr2	6942806	6946733	+	DDB_G0276465	sepA	serine%2Fthreonine-protein kinase that plays a role in the regulation of cleavage furrow formation%3B similar to S. pombe cdc7%3B armadillo repeat-containing protein
chr2	6947282	6947965	-	DDB_G0276565	DDB_G0276565_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	6948162	6948244	-	DDB_G0294925	tRNA-Leu-UAA-4	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	6951075	6952445	-	DDB_G0276567	DDB_G0276567	homolog of S. cerevisiae CDC50 (cell division control protein 50)%2C which is required for polarized cell growth%3B contains two putative transmembrane domains
chr2	6954075	6955794	+	DDB_G0276439	DDB_G0276439	glycoside hydrolase family 25 (GH25) comprises enzymes with lysozyme (EC:3.2.1.17) activity%3B contains a putative N-terminal signal peptide%3B has similarity to %3Ci%3ED. discoideum%3C%2Fi%3E counting factor components cf50 and cf45-1.
chr2	6956284	6957511	-	DDB_G0276441	rpl7	protein component of the large (60S) ribosomal subunit
chr2	6958359	6959628	+	DDB_G0276569	DDB_G0276569	NA
chr2	6959828	6964465	-	DDB_G0276443	usp7	ortholog of H. sapiens USP7 and S. cerevisiae UBP15
chr2	6967980	6974410	+	DDB_G0276571	gnrC	gelsolin domain-containing protein%3B also contains WASP-C (Wiskott-Aldrich Syndrome Protein C-terminal) domains that contain PAK-box%2FP21-Rho-binding domains%3B however%2C these domains are found near the N-terminus (upstream of the gelsolin domain)%2C not at the C-terminus
chr2	6974621	6975419	-	DDB_G0276451	DDB_G0276451	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0276451 has only one recognizable blast hit outside the Amebozoans%3B this is to the proapoptotic protein SIVA. The homology is weak%2C but when vertebrate SIVA is blasted back to Dicty%2C DDB_G0276451 is the only hit. SIVA is a suspected transcriptional target of E2F1 [Fortin et al%2C Journal of Biological Chemistry 279%2C 28706-28714 (2004)]. E2F1 is well known to be bound and inactivated by the retinoblastoma protein. Interestingly%2C DDB_G0276451 is %3Etenfold overexpressed in a Dicty strain lacking the Dicty retinoblastoma homologue (p%3C4e-15). This suggests that DDB_G0276451 is also a direct or indirect E2F target in Dicty. The promoter contains the 8-mer CCCGCCAA%2C which is roughly 20-fold enriched in the promoters of rblA-repressed genes (p%3C2e-13). In Dicty multicellular development%2C DDB_G0276451 shows an expression trajectory (see DictyExpress) which is highly typical of rblA-repressed%2C putative cell-cycle regulated genes. %3Ci%3EHarry MacWilliams%2C May 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0276451%22%3E There is more information on the wiki page%3C%2Fa%3E
chr2	6975985	6977247	+	DDB_G0276573	DDB_G0276573	NA
chr2	6977542	6978818	-	DDB_G0276449	DDB_G0276449	NA
chr2	6979797	6982102	+	DDB_G0276447	DDB_G0276447	has a BAR domain at the N terminus and a DNAJ heat shock N-terminal domain at the carboxyl domain%3B shares a short region of similarity with plant auxilin-like protein%2C a heat shock protein binding
chr2	6982368	6983120	-	DDB_G0276511	DDB_G0276511	NA
chr2	6983477	6983839	-	DDB_G0276513	DDB_G0276513	NA
chr2	6984336	6986396	-	DDB_G0276445	DDB_G0276445	highly similar to human HSPA5 (78 kDa glucose-regulated protein precursor GRP78)%3B contains a predicted endoplasmic reticulum targeting sequence
chr2	6988198	6988464	+	DDB_G0276467	DDB_G0276467	NA
chr2	6988936	6990122	+	DDB_G0276469	syn16B	similar to syntaxin 16%2C a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr2	6990870	6992122	+	DDB_G0276515	DDB_G0276515	NA
chr2	6993306	6994463	+	DDB_G0276575	syn16A	similar to syntaxin 16%2C a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr2	6994954	6998137	-	DDB_G0276577	fray2	the kinase domain is similar to mammalian stress-induced STK and OSR1 (oxidative stress responsive 1) kinases%2C and other STE20-like kinases%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  Fray1 and Fray2  represent the FRAY-subfamily of Ste20-like kinases in D. discoideum  (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FSvkA%22%3Esevkin%3C%2Fa%3E for more information on Ste20 kinases).  In humans this family is represented by OSR (oxidative stress responsive kinase%2C a name that is a bit misleading as nobody showed a link between OSR and oxidative stress) and STLK3%2FSPAK. The fruit fly contains only the kinase Fray in this subfamily.  The Schleicher group is currently characterizing the phenotype of knockout mutants.  %3Cbr%2F%3E %3Ci%3EMeino Rohlfs%2C August 2006 %3C%2Fi%3E
chr2	7002973	7003576	-	DDB_G0276579	msrA	catalyzes the reaction L-methionine %2B thioredoxin disulfide %2B H2O %3D L-methionine (S)-S-oxide %2B thioredoxin%3B functions as a repair enzyme for proteins that have been inactivated by oxidation
chr2	7004296	7004366	+	DDB_G0294879	tRNA-Pro-UGG-7	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr2	7006417	7007268	-	DDB_G0276517	DDB_G0276517_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276559%22%3EDDB_G0276559%3C%2Fa%3E
chr2	7007643	7009310	+	DDB_G0276581	DDB_G0276581	NA
chr2	7009387	7012149	-	DDB_G0276519	mus81	similar to endonuclease Mus81%2C conserved from yeast to human%2C  involved in DNA repair and replication fork stability
chr2	7012325	7012718	-	DDB_G0276521	DDB_G0276521	NA
chr2	7014397	7014847	+	DDB_G0276471	DDB_G0276471	NA
chr2	7015380	7016617	-	DDB_G0276473	DDB_G0276473	NA
chr2	7017424	7020250	-	DDB_G0276583	DDB_G0276583	NA
chr2	7020725	7022745	-	DDB_G0276523	DDB_G0276523	MBOAT family protein%2C membrane proteins that contains a variety of acyltransferase enzymes%3B contains 8 predicted transmembrane domains
chr2	7023841	7024615	+	DDB_G0276475	cfaC	NA
chr2	7025054	7025299	-	DDB_G0276477	DDB_G0276477	NA
chr2	7027413	7027653	-	DDB_G0276585	DDB_G0276585	NA
chr2	7028602	7029201	+	DDB_G0276587	hspG4	NA
chr2	7029406	7029649	-	DDB_G0276589	DDB_G0276589	NA
chr2	7030998	7031238	-	DDB_G0276591	DDB_G0276591	NA
chr2	7032092	7032775	+	DDB_G0276607	hspG3	NA
chr2	7032998	7033245	-	DDB_G0276605	DDB_G0276605	NA
chr2	7034410	7034667	-	DDB_G0276609	DDB_G0276609	NA
chr2	7035596	7036336	-	DDB_G0276603	DDB_G0276603	NA
chr2	7037927	7038667	-	DDB_G0276601	DDB_G0276601	NA
chr2	7039288	7039529	-	DDB_G0276599	DDB_G0276599	NA
chr2	7040401	7041141	-	DDB_G0276597	DDB_G0276597	NA
chr2	7041687	7041946	-	DDB_G0276595	DDB_G0276595	NA
chr2	7042853	7043593	-	DDB_G0276593	DDB_G0276593	NA
chr2	7044161	7044284	-	DDB_G0276611	DDB_G0276611	NA
chr2	7044385	7044546	+	DDB_G0276649	DDB_G0276649	NA
chr2	7045093	7045343	-	DDB_G0276619	DDB_G0276619	NA
chr2	7046443	7046688	+	DDB_G0276621	DDB_G0276621	NA
chr2	7046886	7050545	-	DDB_G0276617	myoC	(unconventional) class I myosin
chr2	7051390	7052039	-	DDB_G0276623	DDB_G0276623	NA
chr2	7053641	7055221	+	DDB_G0276615	hmgB	NA
chr2	7055459	7056902	-	DDB_G0276625	DDB_G0276625	belongs to the drug%2Fmetabolite transporter superfamily%3B similar to human SLC35D1 (UDP-glucuronic acid%2FUDP-N-acetylgalactosamine transporter) and S. cerevisiae VRG4 (GDP-mannose transporter 1)%3B contains 8 putative transmembrane domains
chr2	7057900	7059117	+	DDB_G0276627	DDB_G0276627	NA
chr2	7059622	7059750	-	DDB_G0276629	DDB_G0276629	NA
chr2	7060113	7061161	+	DDB_G0276631	DDB_G0276631	NA
chr2	7061709	7064204	+	DDB_G0276633	DDB_G0276633	NA
chr2	7065552	7065782	-	DDB_G0276647	DDB_G0276647_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr2	7066186	7068110	-	DDB_G0276645	DDB_G0276645_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr2	7068237	7068837	+	DDB_G0276643	DDB_G0276643	NA
chr2	7069335	7069630	-	DDB_G0276641	DDB_G0276641	NA
chr2	7070220	7070520	-	DDB_G0276639	DDB_G0276639	NA
chr2	7072164	7072417	+	DDB_G0276637	DDB_G0276637	NA
chr2	7072784	7073031	-	DDB_G0276635	DDB_G0276635	NA
chr2	7074258	7074497	+	DDB_G0276613	DDB_G0276613	identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276707%22%3E%3Ci%3EDDB_G0276707%3C%2Fi%3E%3C%2Fa%3E
chr2	7074945	7075189	-	DDB_G0349118	DDB_G0349118	NA
chr2	7077584	7077839	+	DDB_G0276707	DDB_G0276707	identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276613%22%3E%3Ci%3EDDB_G0276613%3C%2Fi%3E%3C%2Fa%3E
chr2	7078494	7078736	-	DDB_G0276651	DDB_G0276651	NA
chr2	7079602	7079843	+	DDB_G0276653	DDB_G0276653	NA
chr2	7080607	7080847	+	DDB_G0276655	DDB_G0276655	NA
chr2	7081017	7085437	-	DDB_G0276657	npcB	one of two orthologs of NPC1 (with %3Ca href%3D%22%2Fgene%2FnpcA%22%3EnpcA%3C%2Fa%3E)%2C a Patch family protein%2C mutated in Niemann-Pick disease%2C a form of lipidosis characterized by the accumulation of unestrified cholesterol in the lysosomes%3B contains a signal peptide and 14 predicted transmembrane domains
chr2	7086569	7088581	+	DDB_G0276659	DDB_G0276659_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0283139%22%3EDDB_G0283139%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283243%22%3EDDB_G0283243%3C%2Fa%3E
chr2	7088764	7090818	-	DDB_G0276709	DDB_G0276709	NA
chr2	7091221	7091919	-	DDB_G0276711	rpiA	catalyzes the reaction D-ribose 5-phosphate %3C%3D%3E D-ribulose 5-phosphate
chr2	7093016	7094693	+	DDB_G0276661	DDB_G0276661	NA
chr2	7094813	7097853	-	DDB_G0276663	DDB_G0276663	NA
chr2	7099421	7099810	+	DDB_G0276665	DDB_G0276665_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0290885%22%3EDDB_G0290885%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290887%22%3EDDB_G0290887%3C%2Fa%3E
chr2	7101219	7102214	+	DDB_G0276671	DDB_G0276671	NA
chr2	7102352	7106045	-	DDB_G0276673	DDB_G0276673	NA
chr2	7106291	7107426	+	DDB_G0276675	DDB_G0276675	NA
chr2	7107804	7110920	+	DDB_G0276677	DDB_G0276677	NA
chr2	7112533	7116132	+	DDB_G0276713	DDB_G0276713	NA
chr2	7116545	7117037	-	DDB_G0276679	DDB_G0276679	NA
chr2	7117771	7120184	+	DDB_G0276681	DDB_G0276681	NA
chr2	7120524	7121231	+	DDB_G0276683	DDB_G0276683	NA
chr2	7121701	7122384	-	DDB_G0276717	DDB_G0276717_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	7122699	7122771	+	DDB_G0294881	tRNA-Ala-AGC-2	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7123870	7126334	+	DDB_G0276719	DDB_G0276719	NA
chr2	7126405	7126708	+	DDB_G0276685	DDB_G0276685	related to the hssA genes
chr2	7127174	7127459	-	DDB_G0276687	DDB_G0276687	related to the hssA genes
chr2	7128289	7137016	-	DDB_G0276689	DDB_G0276689	conserved hypothetical protein 
chr2	7137404	7138750	-	DDB_G0276721	tyrS	catalyzes the reaction ATP %2B L-Tyrosine %2B tRNATyr %3D AMP %2B diphosphate %2B L-tyrosyl-tRNATyr
chr2	7140104	7141108	+	DDB_G0276693	DDB_G0276693	NA
chr2	7141543	7143483	+	DDB_G0276695	DDB_G0276695	NA
chr2	7143862	7144625	+	DDB_G0276697	DDB_G0276697	NA
chr2	7144841	7144924	-	DDB_G0294923	tRNA-Leu-CAG-1	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7145278	7145517	-	DDB_G0276699	DDB_G0276699	NA
chr2	7147104	7147351	+	DDB_G0276701	DDB_G0276701	NA
chr2	7148982	7149229	+	DDB_G0276703	DDB_G0276703	NA
chr2	7149874	7150633	+	DDB_G0276705	DDB_G0276705	NA
chr2	7150803	7151040	-	DDB_G0276723	DDB_G0276723	NA
chr2	7151707	7152462	+	DDB_G0276747	DDB_G0276747	NA
chr2	7152617	7152856	-	DDB_G0276749	DDB_G0276749	NA
chr2	7154411	7154651	+	DDB_G0276751	DDB_G0276751	NA
chr2	7155346	7156107	+	DDB_G0276745	DDB_G0276745	NA
chr2	7156375	7156614	-	DDB_G0276743	DDB_G0276743	NA
chr2	7158214	7158471	+	DDB_G0276741	DDB_G0276741	NA
chr2	7159124	7159852	+	DDB_G0276739	DDB_G0276739	NA
chr2	7160082	7160328	-	DDB_G0276737	DDB_G0276737	NA
chr2	7161840	7162080	+	DDB_G0349390	DDB_G0349390	NA
chr2	7162758	7163633	+	DDB_G0276735	DDB_G0276735	NA
chr2	7163692	7165720	-	DDB_G0276755	DDB_G0276755	NA
chr2	7166909	7171855	+	DDB_G0276733	DDB_G0276733	NA
chr2	7172694	7173337	+	DDB_G0276731	DDB_G0276731	NA
chr2	7173981	7174667	+	DDB_G0276729	DDB_G0276729	NA
chr2	7175547	7175678	+	DDB_G0276727	DDB_G0276727	NA
chr2	7175956	7176266	+	DDB_G0276725	DDB_G0276725	contains one RRM (RNA recognition motif) domain
chr2	7176768	7177255	-	DDB_G0276757	sigH	expressed in prespore cells%3B contains two predicted transmembrane domains
chr2	7179136	7182209	+	DDB_G0276919	pldG	similar to human PLD%2C a GPI (glycosylphosphatidylinositol)-specific phospholipase D
chr2	7182465	7183317	-	DDB_G0276921	DDB_G0276921	member of a Dictyostelium-specific gene family%3B contains a signal peptide
chr2	7183824	7184702	-	DDB_G0276923	DDB_G0276923_ps	putative pseudogene%3B highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276925%22%3E%3Ci%3EDDB_G0276925%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276921%22%3E%3Ci%3EDDB_G0276921%3C%2Fi%3E%3C%2Fa%3E
chr2	7185219	7186104	-	DDB_G0276925	DDB_G0276925	member of a Dictyostelium-specific gene family%3B contains a signal peptide
chr2	7187981	7188054	+	DDB_G0294883	tRNA-Phe-GAA-6	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7189408	7191733	+	DDB_G0276883	canA	catalytic subunit of the Ca%3Csup%3E2%2B%3C%2Fsup%3E%2Fcalmodulin-dependent serine%2Fthreonine protein phosphatase
chr2	7191923	7192661	-	DDB_G0276927	DDB_G0276927	NA
chr2	7194376	7196288	+	DDB_G0276761	cotB	expressed in prespore cells
chr2	7196605	7198419	-	DDB_G0276929	DDB_G0276929	NA
chr2	7198772	7199606	-	DDB_G0276765	ubqC	highly conserved gene consisting a a fusion product between ubiquitin and the S27a ribosomal protein
chr2	7200459	7201989	+	DDB_G0277007	DDB_G0277007	homolog of human SLC35C1 (GDP-fucose transporter 1)%3B defects in human SLC35C1 are the cause of leukocyte adhesion deficiency type II%3B contains 10 putative transmembrane domains
chr2	7202546	7203503	+	DDB_G0277009	DDB_G0277009	NA
chr2	7203757	7204951	-	DDB_G0277011	DDB_G0277011	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0277011 is highly similar in an N-terminal domain to the %3Cb%3EShaker%3C%2Fb%3E voltage-gated potassium channel of vertebrates%2C and is the best hit in the Dicty genome when searched with the sequence of this channel. The channel is strongly expressed in several classes of neurons in adult animals%2C and appears to regulate neuronal excitability. The channel is also expressed during embryonic development where it shows a correlation with proliferation [see Hallows and Tempel%2C Journal of Neuroscience 15%2C 5682-5691 (1998)]. Older work shows clear correlation between expression and proliferation in cultured Schwann cells%2C and blockade of potassium conduction inhibits proliferation (reviewed in Hallows and Tempel).%3Cbr%3E DDB_GO277011 is fourfold overexpressed (p%3C3E-70)in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). Most genes whose products have roles in S-phase or mitosis are overexpressed in this strain%2C and most of the overexpressed genes are identifiable with cell cycle progression. This suggests that DDB_GO277011 could be a Dictyostelium proliferation regulator%2C and that the completely mysterious connection between potassium conductance and proliferation could be studied in Dictyostelium. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E
chr2	7205190	7206560	+	DDB_G0277013	ptcG	NA
chr2	7206700	7209693	-	DDB_G0276931	DDB_G0276931	NA
chr2	7210164	7211743	+	DDB_G0276763	captC	catalyzes the reaction CDP-choline %2B 1%2C2-diacylglycerol %3D CMP %2B a phosphatidylcholine%3B most similar to plant genes%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FCaptC%22%3Ecommunity annotation%3C%2Fa%3E
chr2	7212385	7213987	-	DDB_G0276961	DDB_G0276961	C-terminus similar to Arabidopsis thaliana plant adhesion molecule 1%2C Drosophila melanogaster extracellular matrix adhesion protein Pollux and human rab6 GTPase activating protein GAPCENA
chr2	7215630	7216308	-	DDB_G0276967	racF2	enriched in gametes
chr2	7216750	7218586	-	DDB_G0276965	gltA	catalyzes the condensation of acetyl-CoA and oxaloacetate to citrate
chr2	7219497	7220402	+	DDB_G0276933	mcfX	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3B has similarity to the calcium-dependent mitochondrial aspartate and glutamate carriers aralar1 and 2 (slc25A12 and 13)%2C but does not contain a EF-hand calcium-binding domain such as %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283329%22%3E%3Ci%3EmcfO%3C%2Fi%3E%3C%2Fa%3E%3B contains one transmembrane domain%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr2	7220481	7222693	-	DDB_G0276935	DDB_G0276935	NA
chr2	7223776	7224492	+	DDB_G0276937	expl5	similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B contains a predicted signal peptide
chr2	7225140	7225967	-	DDB_G0277015	msp	contains two selenocysteine residues at positions 20 and 88%3B conserved in  the green algae such as Chlamydomonas%2C Ostreococcus%2C and Volvox%3B contains 4 transmembrane domains
chr2	7226683	7230316	-	DDB_G0277017	gxcN	NA
chr2	7234040	7235588	-	DDB_G0276917	psmC2	ATPase subunit and regulatory subcomplex of the 26S proteasome
chr2	7236466	7236615	+	DDB_G0276915	DDB_G0276915	NA
chr2	7237204	7237285	-	DDB_G0294921	tRNA-Ser-AGA-6	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7238641	7241913	+	DDB_G0277019	wdr36	putative U3 snoRNP protein%3B ortholog of H. sapiens WDR36 and S. cerevisiae UTP21%3B WDR36 has been implicated in open angle glaucoma 1 type G (GLC1G)
chr2	7242199	7244136	-	DDB_G0276767	plbA	hydrolyses phosphatidylcholine to glycerophosphocholine and two fatty acids
chr2	7245854	7247870	+	DDB_G0276963	gefH	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form
chr2	7248197	7249372	-	DDB_G0276913	DDB_G0276913	NA
chr2	7249627	7250740	-	DDB_G0277021	DDB_G0277021_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0282839%22%3EDDB_G0282839%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0292474%22%3EDDB_G0292474%3C%2Fa%3E 
chr2	7251359	7252450	-	DDB_G0276911	DDB_G0276911	NA
chr2	7253376	7254244	+	DDB_G0277005	DDB_G0277005_ps	putative pseudogene%3B similar to a larger gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289819%22%3EDDB_G0289819%3C%2Fa%3E
chr2	7254558	7255694	-	DDB_G0276907	DDB_G0276907	NA
chr2	7256369	7257430	-	DDB_G0276905	DDB_G0276905	NA
chr2	7258388	7259413	-	DDB_G0277023	DDB_G0277023	NA
chr2	7259970	7261279	+	DDB_G0277003	DDB_G0277003	NA
chr2	7261455	7261736	-	DDB_G0277001	cpiC	similar to animal and plant cystatin A3%3B member of the stefin cystatin family of cysteine protease inhibitors
chr2	7262534	7263496	+	DDB_G0277025	DDB_G0277025	NA
chr2	7263655	7263918	-	DDB_G0276901	DDB_G0276901	NA
chr2	7264174	7265152	-	DDB_G0276899	DDB_G0276899	conserved hypothetical protein%3B similar to failed axon connections family proteins
chr2	7265714	7266282	-	DDB_G0276759	cbpA	contains four EF hands%3B regulates reorganization of the actin cytoskeleton during cell aggregation
chr2	7267534	7269288	+	DDB_G0276897	DDB_G0276897	conserved hyphothetical protein%3B similar to AprA%2C an autocrine repressor of proliferation
chr2	7269337	7270306	-	DDB_G0276999	DDB_G0276999	contains four transmembrane domains%3B no homolog sequences in other organisms
chr2	7271007	7272048	-	DDB_G0277027	tmem56A	homolog of mammalian TMEM56%3B there are three genes in %3Ci%3EDictyostelium%3C%2Fi%3E: %3Ci%3Etmem56A%3C%2Fi%3E%2C %3Ci%3Etmem56B%3C%2Fi%3E%2C and %3Ci%3Etmem56C%3C%2Fi%3E%3B contains 7 putative transmembrane domains
chr2	7272592	7273552	-	DDB_G0277029	tmem56B	homolog of mammalian TMEM56%3B there are three genes in %3Ci%3EDictyostelium%3C%2Fi%3E: %3Ci%3Etmem56A%3C%2Fi%3E%2C %3Ci%3Etmem56B%3C%2Fi%3E%2C and %3Ci%3Etmem56C%3C%2Fi%3E%3B contains 7 putative transmembrane domains
chr2	7274148	7276949	+	DDB_G0276775	DDB_G0276775_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0271468%22%3EDDB_G0271468%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E
chr2	7277171	7277431	+	DDB_G0295521	rnu2e	component of the spliceosome involved in pre-mRNA splicing
chr2	7277816	7280677	+	DDB_G0276773	DDB_G0276773_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0271468%22%3EDDB_G0271468%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0271438%22%3EDDB_G0271438%3C%2Fa%3E
chr2	7281154	7281415	+	DDB_G0295523	rnu2f	component of the spliceosome involved in pre-mRNA splicing
chr2	7281651	7283492	-	DDB_G0277031	DDB_G0277031	conserved hyphothetical protein%3B similar to AprA%2C an autocrine repressor of proliferation
chr2	7284177	7284949	-	DDB_G0276769	DDB_G0276769	NA
chr2	7287390	7288028	+	DDB_G0276777	DDB_G0276777	NA
chr2	7288118	7289937	-	DDB_G0276779	DDB_G0276779	similar to AAAS%2C also known as achalasia%2C adrenocortical insufficiency%2C alacrimia (Allgrove%2C triple-A)
chr2	7290266	7291176	-	DDB_G0276781	DDB_G0276781	NA
chr2	7291532	7292461	-	DDB_G0276783	DDB_G0276783	homolog of human EXOSC3 (exosome component 3) and S. cerevisiae RRP40 (Ribosomal RNA-processing protein 40)%3B S. cerevisiae RRP40 is a component of the exosome 3%27-%3E5%27 exoribonuclease complex%2C but lacks exonuclease activity
chr2	7293362	7295018	+	DDB_G0276997	DDB_G0276997	contains three transmembrane domains
chr2	7295274	7299183	-	DDB_G0277033	swi3	similar to H. sapiens SWI%2FSNF subunit SMARCC1 and the yeast  subunit SWI3 of the chromatin remodeling complex
chr2	7300081	7300938	-	DDB_G0277035	DDB_G0277035	NA
chr2	7301907	7302348	-	DDB_G0276995	nat_ps	putative pseudogene%3B fragment%3B similar to the nat family of acetyltransferases%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0276993%22%3E%3Ci%3Enat5%3C%2Fi%3E%3C%2Fa%3E 
chr2	7302630	7303499	-	DDB_G0276993	nat5	NA
chr2	7304770	7306212	-	DDB_G0276893	ctxB	member of the alpha-actinin%2Fspectrin superfamily%2C dimerizes with cortexillin I%3B involved in cytokinesis and development and associates with the actin cytoskeleton
chr2	7306921	7308250	-	DDB_G0276785	DDB_G0276785	NA
chr2	7309123	7310965	+	DDB_G0277037	pgs1	ortholog of the mammalian and yeast phosphatidylglycerophosphate synthase 1 that catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis
chr2	7311292	7313178	+	DDB_G0276787	DDB_G0276787	NA
chr2	7313618	7315046	+	DDB_G0277039	DDB_G0277039	very conserved in dictyostelids and similar to bacterial 33 kDa chaperonin proteins
chr2	7315144	7315929	-	DDB_G0276895	DDB_G0276895	NA
chr2	7316822	7318082	+	DDB_G0276795	ctbsB	similar to H. sapiens di-N-acetylchitobiase (CBTS)%2C a hydrolase involved in the degradation of asparagine-linked glycoproteins%3B contains a putative N-terminal signal sequence
chr2	7318662	7320064	+	DDB_G0276793	DDB_G0276793	NA
chr2	7321470	7322125	+	DDB_G0277041	rheb	NA
chr2	7322606	7324991	-	DDB_G0277043	DDB_G0277043	structural similarity to Zn-dependent peptidases%3B contains a a predicted signal anchor sequence%2C and 4 putative transmembrane domains
chr2	7326201	7329026	+	DDB_G0276791	DDB_G0276791	similar to many uncharacterized leucine-rich repeat-containing proteins
chr2	7329318	7329835	-	DDB_G0276789	DDB_G0276789	NA
chr2	7333559	7337443	+	DDB_G0276887	fbxA	F-box and WD40 domains containing protein%3B part of a complex that targets proteins for ubiquination%3B has the same domain composition as %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285445%22%3E%3Ci%3EDDB_G0285445%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E and %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0280895%22%3E%3Ci%3EDDB_G0280895%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr2	7337818	7342248	-	DDB_G0276797	lysA	contains lysin motif%2FLysM domain%3B may be involved in bacterial cell wall degradation
chr2	7343113	7345014	-	DDB_G0277045	DDB_G0277045	NA
chr2	7346120	7348205	+	DDB_G0276799	tfdp2	similar to Homo sapiens transcription factor Dp-2 (E2F dimerization partner 2)%2C which binds to E2F to activate the expression of cell cycle-regulated genes (SwissProt Q14188)
chr2	7348550	7352301	+	DDB_G0277047	DDB_G0277047	NA
chr2	7352564	7355155	-	DDB_G0276801	DDB_G0276801	NA
chr2	7355862	7357238	+	DDB_G0277049	DDB_G0277049	ortholog of S. cerevisiae TAM41%2C a mitochondrial protein involved in protein import into the mitochondrial matrix
chr2	7358123	7360021	+	DDB_G0277051	DDB_G0277051	catalyzes the hydrolysis of the terminal 1%2C2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2%3B some members of this family are responsible for protein N-linked glycosylation%2C while other participate in the degradation of misfolded glycoproteins in the endoplasmic reticulum
chr2	7360384	7362414	-	DDB_G0276803	prp19	ortholog of the Prp19 protein%3B in mammals%2C a nuclear matrix protein protein that plays a role in DNA double-strand break repair%3B in S. cerevisiae and in S. pombe%2C a RNA splicing factor and a ubiquitin-protein ligase%3B contains 6 WD-40 repeats and an N-terminal U-box motif
chr2	7363809	7366166	+	DDB_G0277053	DDB_G0277053	contains a predicted signal anchor sequence and a putative C-terminal transmembrane domain
chr2	7366504	7370032	+	DDB_G0276805	DDB_G0276805	NA
chr2	7370887	7372679	+	DDB_G0276885	casK	CK2 family protein kinase%3B a ubiquitious serine%2Fthreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to casein
chr2	7373453	7374640	+	DDB_G0277055	DDB_G0277055	NA
chr2	7375327	7376634	+	DDB_G0276807	DDB_G0276807	NA
chr2	7376660	7378519	-	DDB_G0276991	DDB_G0276991	NA
chr2	7379194	7382025	-	DDB_G0276989	DDB_G0276989	NA
chr2	7382245	7382652	+	DDB_G0276987	DDB_G0276987	NA
chr2	7382833	7385702	+	DDB_G0277057	DDB_G0277057	NA
chr2	7385987	7386505	+	DDB_G0276809	DDB_G0276809	NA
chr2	7386858	7389738	+	DDB_G0276811	DDB_G0276811	NA
chr2	7389875	7390459	-	DDB_G0276813	DDB_G0276813	weak similarity to NAP family proteins which are involved in nucleosome assembly%3B the SWIM domain is found in variety of prokaryotic and eukaryotic proteins%3B it is predicted to have DNA-binding and protein-protein interaction functions in different contexts
chr2	7390722	7392132	-	DDB_G0276815	DDB_G0276815	contains 7 WD repeats%3B belongs to the WD repeat WDSOF1 family%3B homolog of human WDSOF1%2C S. cerevisiae SOF1%3B S. cerevisiae SOF1 is required for ribosomal RNA processing
chr2	7392401	7393264	-	DDB_G0276817	DDB_G0276817	NA
chr2	7395512	7395922	-	DDB_G0276819	DDB_G0276819	NA
chr2	7397249	7399415	-	DDB_G0276821	DDB_G0276821	similar to antiquitin%2C aldehyde dehydrogenase family 7%3B catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr2	7400698	7402029	-	DDB_G0277059	DDB_G0277059	NA
chr2	7402781	7403413	+	DDB_G0276823	DDB_G0276823	NA
chr2	7403620	7405092	+	DDB_G0348940	DDB_G0348940	NA
chr2	7405279	7406362	+	DDB_G0348941	DDB_G0348941_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0289399%22%3EDDB_G0289399%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0287667%22%3EDDB_G0287667%3C%2Fa%3E
chr2	7407171	7407806	-	DDB_G0277061	dph3	C-terminal half very similar to the conserved DPH3%3B the predicted %3Ci%3EDictyostelium%3C%2Fi%3E protein contains an additional%2C repetitive N-terminal part that is not present in other species
chr2	7408795	7409001	+	DDB_G0276825	DDB_G0276825	NA
chr2	7409167	7410531	+	DDB_G0277063	DDB_G0277063	NA
chr2	7411298	7412542	-	DDB_G0276827	DDB_G0276827	NA
chr2	7412574	7416650	+	DDB_G0276829	ifkB	putative eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase%3B putative protein serine%2Fthreonine kinase%3B related to the GCN2 family of protein kinases%3B contains a kinase domain and a HisRS domain
chr2	7417052	7417729	-	DDB_G0276831	DDB_G0276831	NA
chr2	7418011	7419700	-	DDB_G0276939	pspB	prespore gene%2C expressed in prespore cells
chr2	7423496	7426656	+	DDB_G0276833	gacS	NA
chr2	7427326	7429758	+	DDB_G0277065	DDB_G0277065	contains one La domain and two DM15 repeats
chr2	7430263	7430358	+	DDB_G0294885	tRNA-Ala-UGC-2	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7430633	7431157	+	DDB_G0277067	DDB_G0277067_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	7431540	7433492	+	DDB_G0276983	DDB_G0276983_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	7434539	7434634	-	DDB_G0294919	tRNA-Ala-UGC-3	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7435671	7435744	+	DDB_G0294887	tRNA-Val-AAC-8	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7435825	7437462	+	DDB_G0276981	DDB_G0276981_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr2	7437663	7438262	+	DDB_G0276979	DDB_G0276979_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr2	7439874	7447610	-	DDB_G0277071	dupA	contains both a kinase domain and a phosphatase domain%3B similar to MAP kinase phosphatase in plants and dual-specificty phosphatase 19 in mammals%3B regulates the MAP Kinase response to %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection in %3Ci%3EDictyostelium%3C%2Fi%3E
chr2	7449284	7451310	+	DDB_G0276941	cotA	expressed in prespore cells
chr2	7451944	7453443	+	DDB_G0276835	glnA1	catalyzes the reaction ATP %2B L-glutamate %2B ammonia %3D ADP %2B phosphate %2B L-glutamine
chr2	7454063	7454281	+	DDB_G0276837	DDB_G0276837	NA
chr2	7454940	7455965	+	DDB_G0277073	DDB_G0277073_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0272881%22%3EDDB_G0272881%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0272939%22%3EDDB_G0272939%3C%2Fa%3E
chr2	7457975	7462453	+	DDB_G0277075	detA	similar to human DET1%3B localizes to the nucleus but excluded from the heterochromatin%3B interacts with RepE and is involved in cell type specification during development
chr2	7462954	7464117	+	DDB_G0276839	DDB_G0276839	NA
chr2	7464543	7465730	+	DDB_G0276841	DDB_G0276841	contains no functional domains
chr2	7466122	7468513	+	DDB_G0277077	DDB_G0277077	contains a UvrB%2FUvrC domain%3B however%2C does not share similarity with UvrB or UvrC
chr2	7468613	7470085	-	DDB_G0276843	DDB_G0276843	NA
chr2	7470616	7471251	+	DDB_G0276845	DDB_G0276845	NA
chr2	7471494	7471943	-	DDB_G0277079	cyb5B	cytochrome b5 is a membrane bound hemoprotein that functions as an electron carrier for several membrane bound oxygenases%3B contains a single C-terminal transmembrane domain
chr2	7472098	7473446	-	DDB_G0277081	DDB_G0277081	NA
chr2	7473728	7473801	+	DDB_G0294889	tRNA-Arg-ACG-4	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7474022	7475806	-	DDB_G0277083	uduD1	upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant%3B almost identical to %3Ca href%3D%22%2Fgene%2FDDB_G0283125%22%3E%3Ci%3EuduD2%3C%2Fi%3E%3C%2Fa%3E
chr2	7477013	7478717	-	DDB_G0276969	DDB_G0276969	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283085%22%3E%3Ci%3ED2%3C%2Fi%3E%3C%2Fa%3E%3B contains a predicted signal peptide
chr2	7479610	7481655	-	DDB_G0276847	DDB_G0276847	NA
chr2	7482048	7484657	-	DDB_G0276851	uduH	upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant%3B contains one C-terminal predicted transmembrane domain
chr2	7485197	7486825	-	DDB_G0277087	purH	bifunctional enzyme that catalyzes the reactions N%3Csup%3E10%3C%2Fsup%3E-formyl-H%3Csub%3E4%3C%2Fsub%3EF %2B AICAR %3C%3D%3E tetrahydrofolate %2B phosphoribosyl-formamido-carboxamide and phosphoribosyl-formamido-carboxamide %3C%3D%3E IMP %2B H%3Csub%3E2%3C%2Fsub%3EO%3B expressed in prespore cells
chr2	7487396	7488451	-	DDB_G0277089	commd4	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr2	7488908	7489690	+	DDB_G0276853	DDB_G0276853	NA
chr2	7489987	7492179	+	DDB_G0276855	DDB_G0276855	NA
chr2	7492421	7493909	-	DDB_G0276857	DDB_G0276857	NA
chr2	7494067	7495015	+	DDB_G0277091	DDB_G0277091	NA
chr2	7495473	7496419	+	DDB_G0277093	DDB_G0277093	NA
chr2	7496528	7497987	-	DDB_G0277095	DDB_G0277095	NA
chr2	7498825	7500472	-	DDB_G0277097	uduF	upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr2	7500743	7502145	-	DDB_G0276859	DDB_G0276859	NA
chr2	7502309	7503004	-	DDB_G0277099	uduE	upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr2	7503468	7504825	-	DDB_G0276861	DDB_G0276861	conserved protein of unknown function%3B localizes to adherens junctions in zebrafish
chr2	7505297	7507884	-	DDB_G0276977	rad21	ortholog of RAD21%2FSCC1%2C component of the cohesin complex%2C involved in chromosome cohesion during cell cycle%2C in DNA repair%2C and in apoptosis %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  The role of rad21 in Dictyostelium cell cycle control is supported by its  13-fold overexpression in a Dicty strain lacking the Dicty retinoblastoma-like protein%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E (Doquang et al%2C in preparation). Most genes involved in DNA synthesis and mitosis are overexpressed in this strain.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr2	7509311	7510238	-	DDB_G0277101	rab11C	similar to H. sapiens rab11A
chr2	7511199	7514640	+	DDB_G0277103	DDB_G0277103	NA
chr2	7515236	7515562	+	DDB_G0276863	H4b	one of two identical H4 proteins (other is %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277183%22%3E%3Ci%3EH4a%3C%2Fi%3E%3C%2Fa%3E)%3B component of the H2A-H2B-H3-H4 histone octamer%3B dimerizes with histone H3
chr2	7516807	7518631	+	DDB_G0276943	crtp1	similar to Plasmodium falciparum CRT%2C which confers resistance to chloroquine%3B localizes to intracellular vesicle membranes%3B contains 10 predicted transmembrane domains
chr2	7521491	7522825	-	DDB_G0276975	DDB_G0276975_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	7524451	7524521	+	DDB_G0294891	tRNA-Pro-UGG-8	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr2	7525349	7527903	-	DDB_G0276865	clcB	CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles%3B they assemble to form homo-dimers
chr2	7528689	7531283	+	DDB_G0277105	DDB_G0277105	NA
chr2	7532126	7532798	+	DDB_G0276867	DDB_G0276867	weakly similar to PCNA%3B contains one putative transmembrane domain at the C terminus
chr2	7532909	7534786	-	DDB_G0276945	apm4	NA
chr2	7535075	7535626	+	DDB_G0277107	lsm3	member of heteromeric complexes involved in mRNA splicing (lsm2-8) and mRNA degradation (lsm1-7)
chr2	7537012	7538754	+	DDB_G0276869	psvA	NA
chr2	7539245	7539311	-	DDB_G0295525	sno11b	similar to sno11a%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr2	7539525	7539591	-	DDB_G0295527	sno11a	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr2	7540396	7541303	+	DDB_G0276871	rpl10a	protein component of the large (60S) ribosomal subunit
chr2	7541980	7544115	+	DDB_G0276947	trap1	similar to metazoan TRAP1%3B member of the HSP90 family%3B translocates to mitochondria during the prestarvation response
chr2	7544433	7547025	-	DDB_G0276873	DDB_G0276873	NA
chr2	7547283	7552137	-	DDB_G0277109	DDB_G0277109	NA
chr2	7555133	7557414	+	DDB_G0277111	DDB_G0277111	NA
chr2	7557711	7558988	-	DDB_G0277113	pex16	ortholog of peroxin 16%3B involved in import of proteins into peroxisomes%3B mutations in human homolog cause peroxisomal disorders
chr2	7559689	7562546	+	DDB_G0276877	mybK	contains one Myb DNA-binding domain and one domain present in the SSXT protein family
chr2	7564058	7565770	+	DDB_G0276973	nramp1	ortholog of the mammalian SLC11a1%3B transports iron across the phagolysosomal membrane%3B contains 12 transmembrane domains
chr2	7566354	7567330	+	DDB_G0276879	DDB_G0276879	NA
chr2	7567785	7568933	-	DDB_G0277115	dcx	contains two doublecortin domains involved in microtubule stabilization and bundling%3B functionally interacts with lis1 in cAMP signalling
chr2	7569897	7570418	-	DDB_G0276881	DDB_G0276881	contains one AN1-type zinc finger and one A20-type zinc finger%3B similar to A. thaliana SAP7 (stress-associated protein)
chr2	7572576	7573184	+	DDB_G0276875	hspG5	NA
chr2	7574080	7574712	+	DDB_G0276949	hspG6	NA
chr2	7575967	7576590	+	DDB_G0276951	hspG7	NA
chr2	7576790	7577904	-	DDB_G0277117	DDB_G0277117	NA
chr2	7578926	7579561	+	DDB_G0277119	hspG8	NA
chr2	7579760	7580877	-	DDB_G0277121	DDB_G0277121_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0277117%22%3EDDB_G0277117%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0276955%22%3EDDB_G0276955%3C%2Fa%3E
chr2	7581914	7582519	+	DDB_G0276953	hspG9	NA
chr2	7582702	7583828	-	DDB_G0276955	DDB_G0276955	NA
chr2	7584569	7584690	-	DDB_G0295529	rnu4c	component of the spliceosome involved in pre-mRNA splicing
chr2	7585241	7585465	+	DDB_G0277123	hspG10	NA
chr2	7586125	7587242	-	DDB_G0276957	DDB_G0276957	NA
chr2	7588267	7588599	+	DDB_G0277125	hspG11	NA
chr2	7589219	7593090	-	DDB_G0276959	DDB_G0276959	NA
chr2	7593644	7598450	-	DDB_G0277127	DDB_G0277127_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276959%22%3EDDB_G0276959%3C%2Fa%3E 
chr2	7600198	7601889	+	DDB_G0277137	DDB_G0277137	conserved protein%2C ortholog of mouse adult male hypothalamus cDNA clone:A230106L22
chr2	7601973	7603585	-	DDB_G0277133	DDB_G0277133	NA
chr2	7604054	7604790	-	DDB_G0277135	trappc3	ortholog of the conserved trafficking protein particle complex subunit 3%2C part of the multisubunit TRAPP (transport protein particle) complex (BET3 in yeast)
chr2	7605969	7609442	+	DDB_G0277131	gxcBB	NA
chr2	7609682	7610338	-	DDB_G0277129	DDB_G0277129	NA
chr2	7615234	7617933	+	DDB_G0277147	stkA	transcription factor required for sporulation%3B expressed in prespore cells%3B has 18 amino acids between the two CX2C motifs
chr2	7618079	7618510	-	DDB_G0277207	DDB_G0277207	NA
chr2	7618748	7623136	-	DDB_G0277301	DDB_G0277301	NA
chr2	7623909	7626465	-	DDB_G0277303	phesB	catalyzes the reaction ATP %2B L-phenylalanine %2B tRNAPhe %3D AMP %2B diphosphate %2B L-phenylalanyl-tRNAPhe%3B in S. cerevisiae%2C acts as a tetramer composed of two alpha and two beta subunits
chr2	7627453	7627827	+	DDB_G0277209	DDB_G0277209	NA
chr2	7627913	7632171	-	DDB_G0277211	DDB_G0277211	ortholog of human SKIV2L (SuperKIller Viralicitic 2L) protein%2C and yeast SKI2%2C a helicase required for repressing propagation of dsRNA viruses
chr2	7632373	7633095	-	DDB_G0277305	DDB_G0277305	NA
chr2	7634314	7636910	-	DDB_G0277307	DDB_G0277307	highly similar to H. sapiens LONP1 and S. cerevisiae PIM1%3B Lon protease family members are often located in the mitochondria%3B there is a second Lon protease in Dictyostelium
chr2	7638955	7639970	+	DDB_G0277213	DDB_G0277213	weakly similar to mitochondrial F0 ATP synthase delta chain
chr2	7641137	7643212	+	DDB_G0277309	cnrJ	identified as a suppressor of smlA null mutant cnr10
chr2	7643321	7645619	-	DDB_G0277145	pkaD	NA
chr2	7649277	7651691	+	DDB_G0277311	DDB_G0277311	NA
chr2	7651928	7652000	+	DDB_G0294893	tRNA-Ile-AAU-7	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7652688	7653539	-	DDB_G0277215	iptA	similar to plant pathogenic bacteria Ipt proteins involved in cytokinin synthesis%3B IPP transferases modify both cytoplasmic and mitochondrial tRNAs at A(37) to give isopentenyl A(37)
chr2	7655048	7658539	-	DDB_G0277217	DDB_G0277217	NA
chr2	7659066	7661861	-	DDB_G0277313	DDB_G0277313	similar to TAPT1 (Transmembrane Anterior Posterior Transformation)%2C a conserved eukaryotic gene%3B when mutated in mouse%2C causes skeletal homeotic transformations
chr2	7662227	7664303	-	DDB_G0277219	vps13l	shares a very short region of similarity with VPS13
chr2	7664995	7665923	+	DDB_G0277315	DDB_G0277315	NA
chr2	7667169	7667970	+	DDB_G0277317	DDB_G0277317	NA
chr2	7668593	7670290	+	DDB_G0277167	DDB_G0277167	NA
chr2	7670938	7675094	-	DDB_G0277169	DDB_G0277169	NA
chr2	7675988	7676059	-	DDB_G0294917	tRNA-Asp-GUC-10	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr2	7676172	7676855	+	DDB_G0277299	DDB_G0277299_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	7677105	7677605	+	DDB_G0277297	DDB_G0277297_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	7678365	7679636	-	DDB_G0277171	DDB_G0277171	NA
chr2	7680323	7681410	+	DDB_G0277173	vamp7B	belongs to the v-SNARE family%3B interacts with AP180 (clmA)%2C which retrieves Vamp7B from the contractile vacuole
chr2	7681951	7682036	-	DDB_G0295531	sno6	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr2	7682673	7686024	-	DDB_G0277175	forG	contains an actin-binding FH2 (formin homology 2) domain
chr2	7686538	7688136	-	DDB_G0277177	DDB_G0277177	NA
chr2	7688578	7690161	+	DDB_G0277179	DDB_G0277179	NA
chr2	7690557	7691968	-	DDB_G0277319	atg3	Dictyostelium homolog of yeast atg3
chr2	7692473	7693780	-	DDB_G0277181	DDB_G0277181	NA
chr2	7694600	7696289	+	DDB_G0277321	crtp2	similar to Plasmodium falciparum CRT%2C which confers resistance to chloroquine%3B contains 10 predicted transmembrane domains
chr2	7696333	7697427	-	DDB_G0277323	DDB_G0277323	contains four FNIP repeats%3B similar to CigB and other conserved hypothetical Dictyostelium proteins
chr2	7697697	7698023	-	DDB_G0277183	H4a	one of two identical H4 proteins (other is %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276863%22%3E%3Ci%3EH4b%3C%2Fi%3E%3C%2Fa%3E)%3B component of the H2A-H2B-H3-H4 histone octamer%3B dimerizes with histone H3
chr2	7699060	7706086	+	DDB_G0277185	DDB_G0277185	NA
chr2	7707361	7708479	+	DDB_G0277187	DDB_G0277187	NA
chr2	7708598	7710257	-	DDB_G0305367	DDB_G0305367	NA
chr2	7711176	7714758	+	DDB_G0277325	DDB_G0277325	NA
chr2	7715120	7715191	-	DDB_G0294915	tRNA-Asp-GUC-9	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr2	7715722	7716318	+	DDB_G0277189	DDB_G0277189	NA
chr2	7717198	7722630	+	DDB_G0277221	chcA	clathrin is composed of three heavy chain subunits (ChcA) and three light chain subunits (Clc)
chr2	7723058	7723540	+	DDB_G0277191	DDB_G0277191	NA
chr2	7723793	7727267	-	DDB_G0277327	DDB_G0277327	NA
chr2	7727570	7730093	-	DDB_G0277329	DDB_G0277329	N-terminal region similar to ubiquitin%3B central region contains one von Willebrand factor (vWF) type A domain%3B C-terminal region similar to P-loop containing nucleoside triphosphate hydrolases
chr2	7730515	7731298	-	DDB_G0277193	DDB_G0277193_ps	putative pseudogene%3B similar to many other hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E proteins
chr2	7731826	7732209	-	DDB_G0277195	mrps17	protein component of the mitochondrial small ribosomal subunit
chr2	7732529	7733206	+	DDB_G0277197	DDB_G0277197	NA
chr2	7733653	7738100	+	DDB_G0277199	rpc1	component of the RNA polymerase III complex%3B ortholog of S. cerevisiae RPO31
chr2	7738676	7738757	-	DDB_G0294913	tRNA-Leu-AAG-1	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7738970	7739764	-	DDB_G0277201	DDB_G0277201	NA
chr2	7741603	7744353	+	DDB_G0277223	dgkA	dgkA corresponds to a previously reported myosin II heavy chain kinase designated myosin heavy chain-protein kinase C (MHC-PKC)%3B recent research shows the protein does not contain a protein kinase domain but a diacylglycerol kinase domain
chr2	7744744	7745848	+	DDB_G0277203	DDB_G0277203	members of the NAD-dependent epimerase%2Fdehydratase family use nucleotide-sugar substrates for a variety of chemical reactions
chr2	7746561	7747278	+	DDB_G0277205	DDB_G0277205	NA
chr2	7748048	7750051	+	DDB_G0277225	DDB_G0277225	NA
chr2	7750722	7751531	+	DDB_G0277227	DDB_G0277227	NA
chr2	7752528	7754672	+	DDB_G0277229	DDB_G0277229	NA
chr2	7754832	7755668	-	DDB_G0277231	ndufs8	core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)
chr2	7755927	7757898	+	DDB_G0277295	mcysS	catalyzes the reaction ATP %2B L-cysteine %2B tRNACys %3D AMP %2B diphosphate %2B L-cysteinyl-tRNACys
chr2	7758796	7759151	+	DDB_G0277233	DDB_G0277233	expressed in pstO cells%3B highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0286667%22%3E%3Ci%3EDDB_G0286667%3C%2Fi%3E%3C%2Fa%3E
chr2	7759588	7761384	-	DDB_G0277235	DDB_G0277235	NA
chr2	7761649	7762841	-	DDB_G0277237	fspA	contains 9 putative transmembrane domains%3B potential chemosensory G-protein coupled receptor which may play a role in intracellular signalling
chr2	7763036	7764910	+	DDB_G0277331	DDB_G0277331	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_GO277331 is similar (blasts both ways) to a widely conserved histone lysine methyl transferease called ASHR1 in plants%2C but known as the Set and MYnd Domain-containing protein SMYD3 in metazoans. In humans SMYD3 is upregulated in the majority of colorectal and hepatic cancers%3B it is thought to participate in transactivating genes involved in cell cycle regulation [see Hamamoto et al%2C Nature Cell Biology 6%2C 731-740 (2004)]. The protein binds to the motif %3Cb%3ECCCTCC%3C%2Fb%3E%2C which is found in the promoters of many such genes in humans.%3Cbr%3E DDB_G0277331 is fivefold overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al.%2C in preparation). The SMYD3 target %3Cb%3ECCCTCC%3C%2Fb%3E is rare in Dictyostelium promoters%2C but highly enriched in the promoters of genes which the rblA disruptant overexpresses. Most of these genes have functions in cell cycle progression%3B they include three kifs%2C two DNA polymerases%2C two centrosomal proteins and cdk1. It thus appears likely that DDB_G0277331 is part of a network controlling cell-cycle-specific gene expression in Dictyostelium. %3Ci%3EHarry MacWilliams%2C October 2009%3C%2Fi%3E
chr2	7764969	7770836	-	DDB_G0277239	DDB_G0277239	NA
chr2	7771869	7772912	+	DDB_G0277333	DDB_G0277333	NA
chr2	7773309	7774020	+	DDB_G0277335	DDB_G0277335	putative 22 kDa peroxisomal membrane protein that may be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane
chr2	7774136	7776793	-	DDB_G0277337	DDB_G0277337	NA
chr2	7777377	7778542	+	DDB_G0277149	DDB_G0277149	contains 3 TPR domains%3B homolog of human TTC35  (tetratricopeptide repeat protein 35) 
chr2	7779263	7782556	+	DDB_G0277341	DDB_G0277341	contains a plant homeodomain (PHD) finger%2C a C4HC3 zinc-finger-like motif found in nuclear proteins thought to be involved in chromatin-mediated transcriptional regulation
chr2	7783025	7784465	+	DDB_G0277243	DDB_G0277243	similar to mammalian TNF receptor-associated factors 5 and 6 (TRAF5%2C TRAF6)
chr2	7784936	7787721	+	DDB_G0277343	scfd2	involved in vesicle-mediated transport%3B weakly similar to H. sapiens SCFD2 
chr2	7788092	7789756	+	DDB_G0277139	apm2	NA
chr2	7790152	7794975	+	DDB_G0277291	DDB_G0277291	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr2	7795600	7797187	+	DDB_G0277345	rps3a	protein component of the small (40S) ribosomal subunit
chr2	7797355	7798755	-	DDB_G0277347	DDB_G0277347	NA
chr2	7799232	7802965	+	DDB_G0277245	DDB_G0277245	catalyzes the reaction L-threonine %3C%3D%3E 2-oxobutanoate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr2	7803232	7805043	-	DDB_G0277349	DDB_G0277349	NA
chr2	7806204	7808472	+	DDB_G0277273	phg1B	involved in phagocytosis and substrate adhesion%3B contains 9 transmembrane domains%3B also involved in the intracellular killing of bacteria by determining the stability and cellular amount of the sulfotransferase Kil1
chr2	7808700	7811174	-	DDB_G0277353	DDB_G0277353	NA
chr2	7812708	7814477	-	DDB_G0277143	gpbA	NA
chr2	7816486	7817535	+	DDB_G0277247	apnB	breaks the C-O-P bond 3%27 to an apurinic or apyrimidinic site in DNA
chr2	7817927	7818775	-	DDB_G0277249	DDB_G0277249	contains 5 ankyrin repeats
chr2	7821349	7823358	-	DDB_G0277251	DDB_G0277251	NA
chr2	7823709	7826321	-	DDB_G0277253	mscS	contains mechanosensitive (MS) channel domain which provides protection against hypo-osmotic shock%3B expressed in pstO cells
chr2	7827595	7831164	-	DDB_G0277255	DDB_G0277255	NA
chr2	7833225	7834846	-	DDB_G0277257	DDB_G0277257	NA
chr2	7835294	7835704	+	DDB_G0277259	DDB_G0277259	NA
chr2	7836022	7836432	-	DDB_G0277261	DDB_G0277261	NA
chr2	7837550	7837623	-	DDB_G0294911	tRNA-Arg-ACG-5	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7838828	7839940	-	DDB_G0277355	DDB_G0277355	NA
chr2	7842734	7843801	+	DDB_G0277263	DDB_G0277263	NA
chr2	7844509	7845326	-	DDB_G0277289	pigH	putative glycosyltransferase involved in GPI biosynthesis%3B subunit of the transferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-N-acetylglucosamine to phosphatidylinositol (PI)
chr2	7845634	7845707	+	DDB_G0294895	tRNA-Val-AAC-9	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7848602	7850071	+	DDB_G0277265	DDB_G0277265	NA
chr2	7850366	7853512	-	DDB_G0277357	DDB_G0277357	contains a putative cupin%2C RmlC-type domain found in RmlC%2C a dTDP-sugar isomerase
chr2	7854255	7855280	+	DDB_G0277267	ube2n	putative ortholog of H. sapiens UBE2N and S. cerevisiae UBC13
chr2	7855699	7856957	+	DDB_G0277359	DDB_G0277359	NA
chr2	7857099	7858927	-	DDB_G0277275	poxA	regulated by the MADS-box transcription factor SrfA during development%3B contains a predicted signal peptide
chr2	7860770	7861876	+	DDB_G0277361	DDB_G0277361	NA
chr2	7861958	7862905	-	DDB_G0348565	DDB_G0348565	NA
chr2	7864423	7868216	+	DDB_G0277269	ionA	expressed in pstAB cells and in pstA cells and upper cup during culmination%3B transports ions across membranes using ATP hydrolysis for energy%3B contains 8 transmembrane domains
chr2	7868434	7870935	-	DDB_G0277287	DDB_G0277287	NA
chr2	7871755	7871837	-	DDB_G0294909	tRNA-Leu-UAA-3	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7872301	7873635	+	DDB_G0277285	DDB_G0277285_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	7874573	7876471	-	DDB_G0277283	DDB_G0277283_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr2	7878701	7878782	-	DDB_G0294907	tRNA-Ser-AGA-5	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7879581	7880915	+	DDB_G0277281	DDB_G0277281_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	7882048	7883382	+	DDB_G0277363	DDB_G0277363_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	7883673	7886816	+	DDB_G0277365	DDB_G0277365_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr2	7889390	7889875	+	DDB_G0277367	DDB_G0277367	NA
chr2	7889956	7891526	-	DDB_G0277151	DDB_G0277151	NA
chr2	7892019	7892927	-	DDB_G0277369	DDB_G0277369	similar to SET%2FPhosphatase 2A inhibitor and other NAP domain-containing proteins
chr2	7893420	7896232	-	DDB_G0277165	DDB_G0277165	CAMKL family protein kinase%3B the protein kinase domain is similar to those of the CAMKL%2FBRSK subfamily%2C which are named based on brain-specific expression in human%2C and neuronal expression in worm
chr2	7899822	7900713	-	DDB_G0277371	pabpn1	similar to human PABPN1 (PAB2)%2C which is involved in the 3%27-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail%3B defects in PABPN1 may be the cause of an autosomal dominant oculopharyngeal muscular dystrophy
chr2	7901323	7902457	+	DDB_G0277373	DDB_G0277373	NA
chr2	7902745	7904138	-	DDB_G0277141	cotC	expressed in prespore cells
chr2	7905630	7909062	-	DDB_G0277375	DDB_G0277375	similar to human ARS2 (Arsenite-resistance protein 2)
chr2	7909800	7911113	+	DDB_G0277163	DDB_G0277163	NA
chr2	7911260	7911847	-	DDB_G0277279	DDB_G0277279	NA
chr2	7912606	7913487	+	DDB_G0277161	DDB_G0277161	NA
chr2	7913689	7914705	-	DDB_G0277159	DDB_G0277159	NA
chr2	7915485	7916629	-	DDB_G0277271	DDB_G0277271	NA
chr2	7917419	7918406	+	DDB_G0277157	nubp2	ortholog of the human nucleotide binding protein NUBP2%3B belongs to the highly conserved Mrp%2FNBP35 ATP-binding protein family%3B contains a Zinc finger%2C C4-type domain
chr2	7918767	7920405	+	DDB_G0277155	tom40	homologous to mitochondrial import protein 40 kDa subunit%3B contains a putative transmembrane beta-barrel
chr2	7920699	7922764	-	DDB_G0277377	srpR	mediates the delivery of nascent secretory proteins to the endoplasmic reticulum by the signal recognition particle (SRP)
chr2	7923209	7924171	-	DDB_G0277153	DDB_G0277153	NA
chr2	7927670	7930066	+	DDB_G0277391	DDB_G0277391	NA
chr2	7930691	7932265	-	DDB_G0277389	DDB_G0277389	NA
chr2	7932696	7934913	-	DDB_G0277379	pspD	prespore gene PL3 
chr2	7936345	7936416	+	DDB_G0294897	tRNA-Thr-AGU-14	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr2	7936707	7939143	-	DDB_G0277387	DDB_G0277387	NA
chr2	7940048	7941055	+	DDB_G0277385	DDB_G0277385	NA
chr2	7941454	7943103	-	DDB_G0277383	DDB_G0277383	NA
chr2	7945233	7946318	+	DDB_G0277395	DDB_G0277395	NA
chr2	7946446	7949072	-	DDB_G0277381	cpras1	contains a type A von Willebrand factor (VWFA) domain followed by circularly permuted GTPase domain with the conserved motifs G1-G2 lying downstream of the G3-G4-G5 motifs
chr2	7949669	7951198	+	DDB_G0307284	DDB_G0307284	similar to a D. purpureum protein
chr2	7953876	7955136	+	DDB_G0277481	DDB_G0277481	NA
chr2	7955427	7958282	-	DDB_G0277531	DDB_G0277531	conserved hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E protein%2C contains one EGF-like%2C type 3 domain
chr2	7960057	7962159	+	DDB_G0277413	mkcD	similar to %3Ci%3EDictyostelium mkcA%3C%2Fi%3E and %3Ci%3EmkcB%3C%2Fi%3E%2C and other mitogen-activated protein kinases (Ste20%2FPAK family)
chr2	7962538	7963218	-	DDB_G0277411	DDB_G0277411	NA
chr2	7964365	7965039	-	DDB_G0277409	DDB_G0277409	NA
chr2	7966182	7966559	+	DDB_G0277407	DDB_G0277407	NA
chr2	7966950	7968159	-	DDB_G0277405	DDB_G0277405	NA
chr2	7968732	7970662	-	DDB_G0277505	hbx6	NA
chr2	7970770	7972432	-	DDB_G0277507	DDB_G0277507	NA
chr2	7973999	7976657	+	DDB_G0277483	DDB_G0277483	NA
chr2	7976869	7980480	-	DDB_G0277533	DDB_G0277533	similar to human WDR48%2C a WD repeat endosomal protein
chr2	7981156	7984040	+	DDB_G0277485	dyrk1	similar to dual-specificity tyrosine-phosphorylation regulated kinases (DYRK)
chr2	7984797	7985785	+	DDB_G0277535	rgn	similar to regucalcin%2C a calcium binding protein that controls many cellular functions
chr2	7985968	7986733	+	DDB_G0277487	DDB_G0277487	NA
chr2	7988276	7988674	+	DDB_G0277489	DDB_G0277489	NA
chr2	7989159	7996777	+	DDB_G0277537	DDB_G0277537	subunit of PI4K%2C responsible for the  phosphorylation of phosphatidylinositol (PI) to PI4P (ATP %2B 1-phosphatidyl-1D-myo-inositol %3D ADP %2B 1-phosphatidyl-1D-myo-inositol 4-phosphate)%2C the first committed step in the generation of phosphatidylinositol 4%2C5-bisphosphate (PIP2)%2C a precursor of the second messenger inositol 1%2C4%2C5-trisphosphate (InsP3)
chr2	7996971	7997588	-	DDB_G0277491	hspG12	NA
chr2	7998660	8001018	+	DDB_G0277397	DG1122	NA
chr2	8001157	8003005	-	DDB_G0277493	cct6	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr2	8005050	8007029	+	DDB_G0277495	DDB_G0277495	NA
chr2	8008207	8010029	+	DDB_G0277401	vatB	ortholog of the B subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the B subunit is part of the V1 subunit
chr2	8010617	8013613	-	DDB_G0277539	DDB_G0277539	putative protein tyrosine kinase%3B similar to human wee1%2C inhibitor of mitosis through phosphorylation of cdc2
chr2	8015733	8018280	-	DDB_G0277541	DDB_G0277541	NA
chr2	8019782	8020888	+	DDB_G0277497	aco	%3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with acoA%2C the acyl-CoA oxidase%2C or aco1 and aco2%2C the aconitases
chr2	8021040	8026101	-	DDB_G0277543	DDB_G0277543	contains three CCCH-type zinc fingers and a putative Armadillo-like helical domain
chr2	8026900	8027055	-	DDB_G0277499	DDB_G0277499	NA
chr2	8027686	8031387	+	DDB_G0277399	piaA	required for receptor-mediated activation of adenylyl cyclase%3B  component of the TORC2 (Tor complex 2) with Tor%2C Lst8%2C and Rip3 that plays a role in regulation of adenylate cyclase (ACA) and protein kinase B (PKB) activation during aggregation
chr2	8032217	8033990	+	DDB_G0277511	hpd	catalyzes the reaction 4-hydroxyphenylpyruvate %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E homogentisate %2B CO%3Csub%3E2%3C%2Fsub%3E
chr2	8034298	8035225	-	DDB_G0277417	DDB_G0277417	conserved hypothetical 278 aa Dictyostelium protein
chr2	8036179	8037106	-	DDB_G0277415	DDB_G0277415	conserved hypothetical 278 aa Dictyostelium protein
chr2	8037641	8039242	-	DDB_G0277545	cyp518A1	NA
chr2	8039644	8042304	-	DDB_G0277429	DDB_G0277429	NA
chr2	8043662	8045683	+	DDB_G0277427	DDB_G0277427	NA
chr2	8045819	8047222	-	DDB_G0277547	DDB_G0277547	NA
chr2	8047664	8048590	+	DDB_G0277425	DDB_G0277425	conserved hypothetical 278 aa Dictyostelium protein
chr2	8049469	8050399	+	DDB_G0277423	DDB_G0277423	conserved hypothetical 278 aa Dictyostelium protein
chr2	8051193	8052121	+	DDB_G0277421	DDB_G0277421	conserved hypothetical 278 aa Dictyostelium protein
chr2	8052660	8060701	-	DDB_G0277419	DDB_G0277419	NA
chr2	8066558	8068733	+	DDB_G0277439	cycD	similar to metazoan and plant type-cyclins of the cell cycle group (G1 subgroup)%3B highest similarity to algal cyclin D%3B predicted to interact with the cyclin-dependent kinase CDK1%2F2 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272813%22%3E%3Ci%3Ecdk1%3C%2Fi%3E%3C%2Fa%3E) %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3EDicty cycD lacks the LxCxE %22retinoblastoma-interaction%22 motif found in most D cyclins  of animals and plants%2C although indirect evidence suggests that the LxCxE motif is  functional in Dicty. Dicty cycD transcription does not appear to be changed in the  %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA- mutant%3C%2Fa%3E. Since most Dicty cell cycle genes are strongly overexpressed in this strain  (Doquang et al%2C in preparation) this suggests that Dicty cycD is not involved in cell  cycle regulation. Dicty cycD is upregulated 45x in development  (9 hits in veg cells%2C 409 hits in early culminates in an RNA sequencing study)%3B  thus its main role may be in multicellular differentiation. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C July 2009 %3C%2Fi%3E 
chr2	8068928	8070071	-	DDB_G0277437	nubp1	ortholog of the human nucleotide binding protein NUBP1%3B belongs to the highly conserved Mrp%2FNBP35 ATP-binding protein family
chr2	8070416	8070878	+	DDB_G0277435	dpm3	highly conserved protein involved in GPI biosynthesis%3B stabilizer subunit of the dolichol-phosphate-mannose synthase complex with DPM1 and DPM2
chr2	8071368	8072778	-	DDB_G0277513	DDB_G0277513_ps	putative pseudogene%3B similar to parts of gene %3Ca href%3D%22%2Fgene%2FDDB_G0288459%22%3EDDB_G0288459%3C%2Fa%3E
chr2	8074596	8075565	+	DDB_G0349503	nat6	NA
chr2	8076554	8077553	+	DDB_G0349505	nat7	NA
chr2	8077667	8079208	-	DDB_G0277515	DDB_G0277515	NA
chr2	8079828	8083392	-	DDB_G0277431	DDB_G0277431	NA
chr2	8084436	8084506	-	DDB_G0294905	tRNA-His-GUG-3	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr2	8084696	8086809	+	DDB_G0277519	DDB_G0277519_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	8086854	8089802	+	DDB_G0277521	DDB_G0277521_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	8089978	8090286	+	DDB_G0277523	DDB_G0277523_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	8090925	8094791	-	DDB_G0277525	DDB_G0277525	NA
chr2	8096571	8097513	+	DDB_G0277501	capB	%3Cb%3ECommunity annotation:%3C%2Fb%3E I used an mRNAseq read fitter which is particular friendly to splice variants (in preparation) to determine the developmental time course of the two curated splice variants of capB%2C using the raw data of Dicty Express (courteously provided by G. Shaulsky and A Parikh). Both variants increase in mid to late development%3B splvarB shows%2C in addition%2C a strong peak in veg cells. The curves for the two variants should add up to the curve for the common sequences%2C and this is approximately true during development%2C suggesting that variants A and B account for most of the developmental transcription. In the growth phase%2C however%2C A and B add up to less than the total%2C suggesting that an additional variant exists which is expressed largely or entirely in the growth phase. %3Ci%3EHarry MacWilliams%2C October 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FcapB%22%3E There is a graph for better visualization on the wiki page%3C%2Fa%3E
chr2	8098024	8101621	+	DDB_G0305791	DDB_G0305791_ps	putative pseudogene%3B EGF-like domain-containing protein
chr2	8102198	8105994	+	DDB_G0277555	DDB_G0277555	NA
chr2	8106401	8109993	+	DDB_G0277557	DDB_G0277557	NA
chr2	8110957	8112037	+	DDB_G0277441	rabJ	NA
chr2	8112427	8113998	-	DDB_G0277503	amtA	involved in transporting ammonia out of the cell
chr2	8114815	8116806	+	DDB_G0277443	DDB_G0277443	NA
chr2	8116895	8117316	-	DDB_G0277445	DDB_G0277445	NA
chr2	8117419	8119332	+	DDB_G0277447	DDB_G0277447	NA
chr2	8121319	8122789	+	DDB_G0277449	DDB_G0277449	member of the AGC kinase group%3B similar to kinase domains of SGK (serum and glucocorticoid responsive kinase)%2C Akt%2FPKB and RSK (ribosomal S6 kinase) family members
chr2	8123072	8123762	-	DDB_G0277403	clc	clathrin is composed of three heavy chain subunits (ChcA) and three light chain subunits (Clc)%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with clcA encoding a conserved  chloride channel
chr2	8124262	8125395	+	DDB_G0277451	mgm101	conserved protein in fungi and Dictyostelium%3B in S. cerevisiae%2C required for the repair of oxidative mtDNA damage
chr2	8125465	8127574	-	DDB_G0277559	DDB_G0277559	contains a predicted signal peptide and a putative C-terminal transmembrane domain%3B similar to D. purpureum protein
chr2	8128317	8130866	-	DDB_G0277527	ddx20	ortholog of H. sapiens DDX20%2FGemin 3%2C a component of Cajal bodies (CBs) and Gems%2C nuclear organelles responsible for spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis
chr2	8131041	8131430	+	DDB_G0277453	DDB_G0277453	NA
chr2	8131744	8132569	-	DDB_G0277561	dynC	similar to dynactin 3
chr2	8132946	8134724	-	DDB_G0277455	plbE	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276767%22%3E%3Ci%3EplbA%3C%2Fi%3E%3C%2Fa%3E%2C which catalyzes the hydrolysis of phosphatidylcholine to glycerophosphocholine
chr2	8135123	8135753	-	DDB_G0277563	DDB_G0277563	NA
chr2	8136499	8136957	+	DDB_G0277457	DDB_G0277457	NA
chr2	8137150	8137365	-	DDB_G0277459	DDB_G0277459	NA
chr2	8138236	8138421	-	DDB_G0277461	DDB_G0277461	NA
chr2	8138567	8138776	+	DDB_G0277463	DDB_G0277463	NA
chr2	8139057	8139611	+	DDB_G0277465	DDB_G0277465	NA
chr2	8139803	8141816	+	DDB_G0277467	DDB_G0277467	NA
chr2	8141487	8141559	+	DDB_G0294899	tRNA-Ala-AGC-3	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	8142776	8143417	+	DDB_G0277469	DDB_G0277469	NA
chr2	8143567	8145072	-	DDB_G0277471	DDB_G0277471	homolog of human PAAF1 (proteasomal ATPase-associated factor 1) which inhibits proteasome 26S assembly and activity%3B contains 3 WD repeats 
chr2	8145872	8146735	+	DDB_G0277473	DDB_G0277473	NA
chr2	8147736	8149203	+	DDB_G0277475	DDB_G0277475	NA
chr2	8149300	8151585	-	DDB_G0277477	DDB_G0277477	catalyzes the reaction acyl-CoA %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E trans-2%2C3-dehydroacyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr2	8152464	8154059	+	DDB_G0277479	DDB_G0277479	NA
chr2	8154194	8155649	-	DDB_G0277565	syn5	similar to syntaxin 5%2C a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr2	8158069	8160501	+	DDB_G0277571	DDB_G0277571	NA
chr2	8161171	8162607	+	DDB_G0277569	DDB_G0277569	members of this family are membrane proteins involved in long chain fatty acid elongation systems that produce 26-carbon precursors for ceramide and sphingolipid synthesis%3B contains 7 putative transmembrane domains
chr2	8163219	8164979	-	DDB_G0277567	DDB_G0277567	NA
chr2	8169746	8170132	-	DDB_G0277575	DDB_G0277575	conserved hypothetical protein predicted to contain four transmembrane domains 
chr2	8170344	8171360	+	DDB_G0277573	DDB_G0277573	NA
chr2	8171700	8172988	+	DDB_G0277577	DDB_G0277577	NA
chr2	8175755	8177761	+	DDB_G0277589	gtaC	has 18 amino acids between the two CX2C motifs%3B expressed in the lower and upper cups and the basal disc%3B involved in DIF signaling leading to pstB cell sorting and basal disc formation%3B shuttles between nucleus and cytoplasm during oscillatory cAMP waves
chr2	8180376	8182370	+	DDB_G0277591	gtaH	has 18 amino acids between the two CX2C motifs
chr2	8183598	8183862	+	DDB_G0277593	DDB_G0277593	NA
chr2	8184492	8186149	-	DDB_G0277615	DDB_G0277615	proteins containing the actin depolymerisation factor (ADF)%2Fcofilin-like domain sever actin filaments and bind to actin monomers
chr2	8186997	8190749	-	DDB_G0277637	DDB_G0277637	NA
chr2	8191422	8195405	+	DDB_G0277639	DDB_G0277639	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8196187	8198614	+	DDB_G0277641	DDB_G0277641_ps	putative pseudogene%3B very similar to neighboring genes that belong  to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8198851	8202750	+	DDB_G0277643	DDB_G0277643	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8203285	8203521	-	DDB_G0277617	DDB_G0277617_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0280757%22%3EDDB_G0280757%3C%2Fa%3E 
chr2	8204055	8208116	+	DDB_G0277645	DDB_G0277645	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8209423	8209563	-	DDB_G0277595	DDB_G0277595	conserved hypothetical Dictyostelium protein%3B identical to %3Ca href%3D%22%2Fgene%2FDDB_G0294605%22%3EDDB_G0294605%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0269070%22%3EDDB_G0269070%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274459%22%3EDDB_G0274459%3C%2Fa%3E
chr2	8210587	8214398	+	DDB_G0277647	DDB_G0277647_ps	putative pseudogene%3B very similar to neighboring genes that belong  to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8214671	8218762	+	DDB_G0305520	DDB_G0305520	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8219196	8223353	+	DDB_G0277619	DDB_G0277619	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8224157	8226674	+	DDB_G0277651	DDB_G0277651_ps	putative pseudogene%3B very similar to neighboring genes that belong  to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8227373	8227802	-	DDB_G0277621	DDB_G0277621_ps	putative pseudogene%3B fragment%3B similar to D. discoideum genes  %3Ca href%3D%22%2Fgene%2FDDB_G0289399%22%3EDDB_G0289399%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0287667%22%3EDDB_G0287667%3C%2Fa%3E
chr2	8228651	8232523	+	DDB_G0277585	DDB_G0277585	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8233577	8233869	-	DDB_G0277587	colA_ps9	putative pseudogene%3B small fragment similar to the large colossin A gene  %3Ca href%3D%22%2Fgene%2FDDB_G0292696%22%3E%3Ci%3EcolA%3C%2Fi%3E%3C%2Fa%3E
chr2	8234081	8234612	+	DDB_G0277623	DDB_G0277623_ps	putative pseudogene%3B small fragment very similar to neighboring genes that belong  to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8235037	8238765	+	DDB_G0277653	DDB_G0277653	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8239430	8243618	+	DDB_G0305538	DDB_G0305538	very similar to neighboring genes that belong  to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8243854	8246908	+	DDB_G0277655	DDB_G0277655_ps	putative pseudogene%3B very similar to neighboring genes that belong  to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8247429	8251616	+	DDB_G0277657	DDB_G0277657	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8252136	8256299	+	DDB_G0277659	DDB_G0277659	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8257035	8261279	+	DDB_G0277661	DDB_G0277661	belongs to a large D. discoideum protein family of unknown function%2C many clustered on chr 2
chr2	8262203	8263749	+	DDB_G0277597	gpt3	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr2	8263837	8264397	-	DDB_G0277599	DDB_G0277599	NA
chr2	8264672	8265361	-	DDB_G0277583	DDB_G0277583	NA
chr2	8265860	8269194	-	DDB_G0277663	DDB_G0277663	NA
chr2	8269607	8270869	-	DDB_G0277625	DDB_G0277625	contains 3 predicted transmembrane domains
chr2	8271819	8272437	+	DDB_G0277665	DDB_G0277665	NA
chr2	8272981	8274558	-	DDB_G0277581	DDB_G0277581	NA
chr2	8277760	8280433	+	DDB_G0277627	tgrR2	NA
chr2	8280728	8282193	-	DDB_G0277629	rpl7a	protein component of the large (60S) ribosomal subunit%3B ribosomal protein L7a homolog
chr2	8282560	8283317	-	DDB_G0277631	DDB_G0277631	NA
chr2	8286817	8288311	+	DDB_G0277667	DDB_G0277667	uncharacterized conserved protein with cyclin domain
chr2	8289542	8289801	-	DDB_G0277633	DDB_G0277633_ps	putative pseudogene%3B small fragment%2C similar to prespore specific (psp) -  and spore coat (cot) protein encoding genes
chr2	8290826	8290896	+	DDB_G0294901	tRNA-His-GUG-2	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr2	8291535	8293100	+	DDB_G0277601	DDB_G0277601	NA
chr2	8293206	8294334	-	DDB_G0277669	DDB_G0277669	similar to aldose 1-epimerase (mutarotase)%2C the enzyme responsible for the anomeric interconversion of D-glucose and other aldoses between their alpha- and beta-form
chr2	8295204	8298020	+	DDB_G0277603	DDB_G0277603	NA
chr2	8298219	8298683	-	DDB_G0277605	DDB_G0277605	NA
chr2	8299059	8299852	-	DDB_G0277607	DDB_G0277607	NA
chr2	8301218	8302591	+	DDB_G0277671	rpc4	component of the RNA polymerase III complex%3B weakly similar to H. sapiens RPC4 and S. cerevisiae RPC53
chr2	8302904	8303591	+	DDB_G0295657	ndufs4	ortholog of H. sapiens NDUFS4%2C a component of the largest respiratory chain complex%3B defects in NDUFS4 are a cause of complex I mitochondrial respiratory chain deficiency
chr2	8303967	8304009	-	DDB_G0295533	r45	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr2	8304316	8304369	-	DDB_G0295535	r29	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr2	8305176	8306165	+	DDB_G0277635	rps27	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S27 homolog
chr2	8306699	8310321	+	DDB_G0277611	ptcK	NA
chr2	8310859	8311326	+	DDB_G0277613	DDB_G0277613	NA
chr2	8312031	8312444	+	DDB_G0277673	DDB_G0277673	NA
chr2	8312721	8313866	+	DDB_G0277697	DDB_G0277697	conserved protein%3B similar to DDB_G0278913
chr2	8316109	8321865	+	DDB_G0277687	DDB_G0277687	NA
chr2	8322084	8323474	+	DDB_G0277689	pcp2	NA
chr2	8323828	8328506	+	DDB_G0277691	cog1	similar to COG1%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits
chr2	8329000	8331264	+	DDB_G0277693	DDB_G0277693	NA
chr2	8331577	8333980	-	DDB_G0277675	DDB_G0277675	NA
chr2	8335817	8342473	+	DDB_G0277685	DDB_G0277685	NA
chr2	8344683	8345971	+	DDB_G0277695	DDB_G0277695	NA
chr2	8346240	8346807	-	DDB_G0277677	rpb11	component of the RNA polymerase II complex%3B ortholog of S. cerevisiae RPB11
chr2	8347286	8348386	+	DDB_G0277679	DDB_G0277679	NA
chr2	8349001	8350656	-	DDB_G0277681	bzpH	NA
chr2	8352571	8354094	-	DDB_G0277705	DDB_G0277705	NA
chr2	8354614	8357036	-	DDB_G0277707	DDB_G0277707	NA
chr2	8357628	8357933	+	DDB_G0277709	DDB_G0277709	NA
chr2	8359557	8362991	-	DDB_G0277711	DDB_G0277711_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	8363091	8364446	-	DDB_G0277713	DDB_G0277713_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr2	8364904	8364976	+	DDB_G0294903	tRNA-Ala-AGC-4	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr2	8365162	8365845	+	DDB_G0277715	DDB_G0277715_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr2	8366249	8367026	-	DDB_G0277699	DDB_G0277699	NA
chr2	8367690	8368775	+	DDB_G0277701	apeA	AP-endonuclease%2C catalyses the exonucleolytic cleavage of damaged double stranded DNA in the 3%27- to 5%27-direction to yield nucleoside 5%27-phosphates
chr2	8369439	8370133	+	DDB_G0277703	aplF	NA
chr2	8370232	8370653	-	DDB_G0277717	DDB_G0277717	NA
chr2	8370803	8372608	+	DDB_G0277787	DDB_G0277787	NA
chr2	8373298	8375811	-	DDB_G0277767	DDB_G0277767	NA
chr2	8375987	8377795	-	DDB_G0277723	lip5	similar to the human lipase family%3B catalyzes the reaction: Triacylglycerol %2B H%3Csub%3E2%3C%2Fsub%3EO %3D diacylglycerol %2B a carboxylate
chr2	8379878	8380941	-	DDB_G0277725	thfA	catalyzes the reaction 5%2C10-methylenetetrahydrofolate %2B NAD%3Csup%3E%2B%3C%2Fsup%3E %3D 5%2C10-methenyl-tetrahydrofolate %2B NADH %2B H%3Csup%3E%2B%3C%2Fsup%3E%3B enriched in prespore cells
chr2	8381890	8385404	+	DDB_G0277789	DDB_G0277789	similar to a conserved eukaryotic protein%3B contains two transmembrane domains
chr2	8385798	8387972	-	DDB_G0277727	uroc1	catalyzes the reaction 3-(5-oxo-4%2C5-dihydro-3H-imidazol-4-yl)propanoate %3C%3D%3E urocanate %2B H%3Csub%3E2%3C%2Fsub%3EO%2C the second step in the degradation of histidine
chr2	8389301	8390209	+	DDB_G0277729	DDB_G0277729	similar to cfaA
chr2	8390719	8395307	+	DDB_G0277719	DDB_G0277719	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B REMI mutant form aberrant fruiting bodies (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0277719%22%3Ecommunity annotation%3C%2Fa%3E) 
chr2	8396089	8400726	+	DDB_G0277731	DDB_G0277731	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr2	8401462	8402411	+	DDB_G0277791	racO	NA
chr2	8402743	8406060	+	DDB_G0277733	valS1	catalyzes the reaction ATP %2B L-valine %2B tRNAVal %3D AMP %2B diphosphate %2B L-valyl-tRNAVal
chr2	8406382	8407197	+	DDB_G0277735	DDB_G0277735	NA
chr2	8407484	8410406	+	DDB_G0277737	DDB_G0277737	NA
chr2	8410519	8410833	-	DDB_G0277739	DDB_G0277739	highly similar to neighboring gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277741%22%3E%3Ci%3EDDB_G0277741%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E%3B expression positively regulated by STATa
chr2	8411530	8411881	+	DDB_G0277741	DDB_G0277741	contains a predicted coiled-coil region found in a group of Dictyostelium proteins known to be regulated by cAMP%3B highly similar to neighboring gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277739%22%3E%3Ci%3EDDB_G0277739%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E%3B expression positively regulated by STATa
chr2	8412296	8413542	+	DDB_G0277793	DDB_G0277793	conserved hypothetical protein%3B contains a putative signal peptide
chr2	8413951	8414547	+	DDB_G0277769	DDB_G0277769	putative secreted protein%3B contains a signal sequence
chr2	8415694	8416035	+	DDB_G0277795	DDB_G0277795	NA
chr2	8416365	8417264	+	DDB_G0277771	DDB_G0277771	NA
chr2	8417392	8419068	+	DDB_G0277743	guaD	catalyzes the reaction guanine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E xanthine %2B NH%3Csub%3E3%3C%2Fsub%3E
chr2	8419128	8420009	-	DDB_G0277745	DDB_G0277745	similar to bacterial phosphatase YidA 
chr2	8420426	8421364	-	DDB_G0277747	DDB_G0277747	NA
chr2	8422539	8426036	+	DDB_G0277797	sec24l	component of COPII (coat protein complex II) involved in ER to Golgi transport%3B similar to SEC24C and SEC24D
chr2	8427032	8429425	+	DDB_G0277799	DDB_G0277799	NA
chr2	8429520	8431406	-	DDB_G0277801	gtpbp5	similar to human GTPBP5%2C GTP1%2FOBG family protein involved in the ribosome maturation process
chr2	8431684	8432899	+	DDB_G0277803	rpl4	protein component of the large (60S) ribosomal subunit%3B ribosomal protein L4 homolog
chr2	8433000	8433995	+	DDB_G0277805	DDB_G0277805	NA
chr2	8434187	8439320	+	DDB_G0277749	DDB_G0277749	NA
chr2	8439922	8441827	+	DDB_G0277807	DDB_G0277807	NA
chr2	8442320	8443193	+	DDB_G0277809	cfaA	NA
chr2	8443492	8444246	+	DDB_G0277811	cfaB	NA
chr2	8444919	8445766	+	DDB_G0277753	DDB_G0277753	similar to cfaA
chr2	8445920	8448331	+	DDB_G0277813	DDB_G0277813	NA
chr2	8448576	8450696	-	DDB_G0277815	acsA	catalyzes the reaction ATP %2B acetate %2B CoA %3D AMP %2B diphosphate %2B acetyl-CoA
chr2	8451915	8454935	+	DDB_G0277755	dclre1	DNA repair metal-beta-lactamase domain-containing protein%2C required for double-strand break repair%2C specifically for non-homologous end joining (NHEJ%3B related to the NHEJ DNA repair protein Artemis
chr2	8456100	8457227	+	DDB_G0277757	DDB_G0277757	NA
chr2	8457984	8459054	+	DDB_G0277759	phyA	catalyzes the hydroxylation of Proline 143 of the Skp1 protein (FpaA%2FFpaB)
chr2	8459161	8460978	-	DDB_G0277817	alg10	CAZy family GT59%3B catalyzes N-linked glucosylation
chr2	8461506	8463173	-	DDB_G0277773	DDB_G0277773	NA
chr2	8463906	8465540	+	DDB_G0277721	fszA	NA
chr2	8465643	8466380	-	DDB_G0277775	DDB_G0277775	homolog of human PIN4 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 4) 
chr2	8467444	8470296	+	DDB_G0277777	DDB_G0277777	NA
chr2	8470556	8471194	+	DDB_G0277761	DDB_G0277761	similar to bacterial endoribonucleases%3B similar to human HRSP12 (ribonuclease UK114)%2C an endoribonuclease which cleaves mRNA and inhibits protein synthesis 
chr2	8471398	8473197	-	DDB_G0277763	DDB_G0277763	NA
chr2	8476009	8476167	+	DDB_G0277765	DDB_G0277765_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2	8476605	8477119	+	DDB_G0277779	DDB_G0277779_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2	8478382	8479424	+	DDB_G0277781	DDB_G0277781_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2	8480176	8480847	+	DDB_G0277783	DDB_G0277783_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2	8480964	8481353	+	DDB_G0277785	DDB_G0277785_TE	ORF2 (contains 2 introns) encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2	8481872	8482919	-	DDB_G0277819	DDB_G0277819	NA
chr2	8483067	8483570	-	DDB_G0277821	DDB_G0277821_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chr2F	58575	59763	-	DDB_G0294144	DDB_G0294144_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	59839	60174	-	DDB_G0294146	DDB_G0294146_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	67862	68308	-	DDB_G0294164	DDB_G0294164_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	69298	69640	+	DDB_G0294168	DDB_G0294168_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	71150	71488	+	DDB_G0294170	DDB_G0294170	NA
chr2F	74762	75168	-	DDB_G0294176	DDB_G0294176_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	76375	77139	+	DDB_G0294178	DDB_G0294178	NA
chr2F	77984	79718	+	DDB_G0294180	DDB_G0294180_RTE	ORF1%2FORF3 protein fusion fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	84098	85966	+	DDB_G0294190	DDB_G0294190_TE	ORF2 (contains 2 introns) encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2F	86273	87659	+	DDB_G0294192	DDB_G0294192	NA
chr2F	88167	89185	-	DDB_G0294194	DDB_G0294194	NA
chr2F	89209	90797	-	DDB_G0294196	DDB_G0294196	NA
chr2F	92348	92812	+	DDB_G0294198	DDB_G0294198	NA
chr2F	92934	94442	+	DDB_G0294200	DDB_G0294200	NA
chr2F	94830	95277	+	DDB_G0294202	DDB_G0294202	NA
chr2F	95619	95986	+	DDB_G0294204	DDB_G0294204_RTE	partial ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	96213	96713	+	DDB_G0294206	DDB_G0294206_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	98771	99221	-	DDB_G0294210	DDB_G0294210_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	101571	101744	+	DDB_G0294212	DDB_G0294212_RTE	fragment of ORF1 encoding an amino-terminal domain of unknown function of long terminal repeat retrotransposon DGLT-B%3B refer to AF474004 for full-length consensus element
chr2F	101914	102213	+	DDB_G0294214	DDB_G0294214	NA
chr2F	102874	103272	+	DDB_G0294216	DDB_G0294216_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	103432	103770	-	DDB_G0294218	DDB_G0294218_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	104219	106571	+	DDB_G0294220	DDB_G0294220	NA
chr2F	107539	107880	+	DDB_G0294222	DDB_G0294222	NA
chr2F	107928	108848	+	DDB_G0294224	DDB_G0294224_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2F	109001	109953	+	DDB_G0294226	DDB_G0294226_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2F	110054	110728	-	DDB_G0294228	DDB_G0294228_RTE	fragment of long terminal repeatretrotransposon skipper ORF2%3B L%3B refer to GenBank AF049230 for full length consensus element
chr2F	111608	111847	-	DDB_G0294230	DDB_G0294230_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	112862	113167	-	DDB_G0294232	DDB_G0294232_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	114657	118818	+	DDB_G0294236	DDB_G0294236_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr2F	119553	120607	+	DDB_G0294238	DDB_G0294238	NA
chr2F	120754	121018	-	DDB_G0294240	DDB_G0294240_ps	putative pseudogene%3B similar to a D. discoideum gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0295813%22%3EDDB_G0295813%3C%2Fa%3E
chr2F	122350	122423	+	DDB_G0294663	tRNA-Phe-GAA-2	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr2F	122435	123171	+	DDB_G0294242	DDB_G0294242_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2F	123269	123469	+	DDB_G0294244	DDB_G0294244_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr2F	124274	125190	-	DDB_G0294246	DDB_G0294246_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr2F	126935	127471	+	DDB_G0294248	DDB_G0294248_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	127607	127774	+	DDB_G0294250	DDB_G0294250_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	127901	128080	+	DDB_G0294252	DDB_G0294252_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	128112	128807	+	DDB_G0294254	DDB_G0294254_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	128878	129423	+	DDB_G0294256	DDB_G0294256_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr2F	131900	133626	-	DDB_G0294262	DDB_G0294262_TE	ORF2 (contains 2 introns) encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2F	134067	135917	+	DDB_G0294264	DDB_G0294264_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2F	136078	136749	+	DDB_G0294266	DDB_G0294266_TE	ORF2 (contains 2 introns) encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2F	138531	139723	-	DDB_G0294268	DDB_G0294268_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon Tdd-5%3B refer to AF298206 for full-length consensus element
chr2F	139855	140475	+	DDB_G0294270	DDB_G0294270	NA
chr2F	140570	140983	+	DDB_G0294272	DDB_G0294272	NA
chr2F	141105	141338	+	DDB_G0294274	DDB_G0294274	NA
chr2F	141425	141631	+	DDB_G0294276	DDB_G0294276	NA
chr2F	141962	142360	+	DDB_G0294278	DDB_G0294278	NA
chr2F	142778	144258	-	DDB_G0294280	DDB_G0294280_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	145863	146363	+	DDB_G0294282	DDB_G0294282_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	148976	150951	+	DDB_G0294286	DDB_G0294286_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	151817	152232	-	DDB_G0294288	DDB_G0294288_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	154409	154670	-	DDB_G0294300	DDB_G0294300_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	154946	156194	+	DDB_G0294302	DDB_G0294302	NA
chr2F	156819	157277	+	DDB_G0294308	DDB_G0294308_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr2F	157595	158497	+	DDB_G0294310	DDB_G0294310_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr2F	159792	161731	+	DDB_G0294314	DDB_G0294314	NA
chr3	12156	14409	-	DDB_G0277925	pif1	very similar to the conserved DNA helicase PIF1%2C in S. cerevisiae involved in telomere formation and elongation
chr3	15087	16133	+	DDB_G0277923	empD	NA
chr3	16340	20087	-	DDB_G0277927	mybH	contains two Myb DNA-binding domains
chr3	22082	25453	+	DDB_G0295679	DDB_G0295679	NA
chr3	26113	29204	+	DDB_G0278585	DDB_G0278585	similar to other Dictyostelium proteins
chr3	29762	30529	-	DDB_G0277931	DDB_G0277931	NA
chr3	30749	31638	+	DDB_G0277933	DDB_G0277933_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0292334%22%3EDDB_G0292334%3C%2Fa%3E
chr3	32370	32788	+	DDB_G0295681	DDB_G0295681	NA
chr3	32996	35686	+	DDB_G0277937	DDB_G0277937	NA
chr3	36191	37385	+	DDB_G0278587	DDB_G0278587	NA
chr3	37703	39178	-	DDB_G0277939	DDB_G0277939	NA
chr3	39336	40956	+	DDB_G0277941	DDB_G0277941	similar to HIRA%2C histone cell cycle regulation defective homolog A
chr3	41608	42450	+	DDB_G0295839	DDB_G0295839	similar to a D. purpureum protein
chr3	42510	44486	-	DDB_G0277943	parG	degrades poly (ADP-ribose) polymers into monomeric subunits%3B important for intracellular levels of poly (ADP-ribose) 
chr3	44863	47023	+	DDB_G0277945	nol9	ortholog of H. sapiens NOL9%3B similar to S. cerevisiae GRC3 believed to be involved in rRNA processing
chr3	47291	48755	-	DDB_G0277947	shmt1	cytoplasmic serine hydroxymethyltransferase%3B catalyzes the reaction L-serine %2B tetrahydrofolate %3C%3D%3E L-glycine %2B 5%2C10-methylene-tetrahydrofolate %2B H%3Csub%3E2%3C%2Fsub%3EO
chr3	49404	54446	-	DDB_G0277949	pldC	catalyzes the reaction a phosphatidylcholine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E choline %2B a phosphatidate
chr3	55112	55969	-	DDB_G0277951	DDB_G0277951	conserved uncharacterized protein
chr3	56545	59868	+	DDB_G0277953	ints6	ortholog of integrator complex subunit 6%2C component of a multiprotein mediator of small nuclear RNA processing%2C a possible tumor suppressor
chr3	60115	61588	-	DDB_G0277955	nup43	component of the nuclear pore complex%3B contains four WD40 repeats
chr3	62453	64198	+	DDB_G0277957	DDB_G0277957	putative ras GTPase-activating protein-binding protein%3B similar to H. sapiens ras GTPase-activating protein-binding protein 1 (G3BP1)
chr3	64771	66738	+	DDB_G0277959	cupJ	similar to calcium up-regulated genes
chr3	66831	68282	-	DDB_G0277961	DDB_G0277961	NA
chr3	68797	70424	-	DDB_G0277963	DDB_G0277963	NA
chr3	70947	71412	-	DDB_G0277965	DDB_G0277965	NA
chr3	72018	75420	+	DDB_G0277967	DDB_G0277967	NA
chr3	76885	77611	+	DDB_G0277859	mlcE	component of actin-based molecular motor%3B myosin II (conventional myosin) component
chr3	78242	79471	+	DDB_G0277969	DDB_G0277969	NA
chr3	79952	80553	+	DDB_G0295697	rabif	NA
chr3	80768	81314	-	DDB_G0277971	vatG	ortholog of the G subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the G subunit is part of the V1 subunit
chr3	83008	83922	+	DDB_G0277973	DDB_G0277973	NA
chr3	84465	84632	-	DDB_G0277839	cxgS	NA
chr3	85494	85655	-	DDB_G0277837	cxgE	NA
chr3	87206	87758	+	DDB_G0277975	rpl14	protein component of the large (60S) ribosomal subunit
chr3	88368	91113	+	DDB_G0277977	xab2	highly similar to vertebrate XAB2 (although XPA is not present in Dictyostelium) involved in transcription-coupled repair and yeast SYF1 (SYnthetic lethal with cdcForty) involved in pre-mRNA splicing and regulation of cell cycle progression
chr3	91596	92285	-	DDB_G0277979	H3v2	NA
chr3	92490	92942	-	DDB_G0277981	DDB_G0277981_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0277941%22%3EDDB_G0277941%3C%2Fa%3E 
chr3	93233	93933	-	DDB_G0277897	racI	NA
chr3	94751	95592	+	DDB_G0277895	DDB_G0277895	C-terminal part contains PPQQPYGA repeats with similarity to Neurospora crassa annexin XIV and Dictyostelium annexin VII repeats
chr3	95820	96613	+	DDB_G0277893	tmem128	contains four transmembrane domains
chr3	96863	97960	-	DDB_G0277891	rimA	ortholog of S. cerevisiae RIM2 and mammalian SLC25a36%2C a mitochondrion carrier protein that imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates 
chr3	98599	99531	-	DDB_G0277983	tbcB	NA
chr3	99770	100324	-	DDB_G0277985	DDB_G0277985	NA
chr3	102264	108452	+	DDB_G0277883	dhkJ	NA
chr3	109696	112817	+	DDB_G0278581	psiF	forms a discoidin-inducing complex (DIC) with dicB%2C pdsA%2C and an unknown protein%3B contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 8 Dictyostelium (CTDC) repeats and a C-terminal transmembrane domain
chr3	113091	113951	-	DDB_G0277875	ssbA	NA
chr3	114291	118239	-	DDB_G0277987	gxcA	Rac guanyl-nucleotide exchange factor involved in chemotaxis and development%3B there are two transcripts for this gene that seem to be differentially expressed during development%2C with the shorter isoform expressed in vegetative cells and the longer isoform during development
chr3	119614	124962	+	DDB_G0277989	DDB_G0277989	contains two kinase domains
chr3	125579	126515	+	DDB_G0277991	etfb	electron transfer flavoprotein (ETF) serves as a specific electron acceptor for several dehydrogenases%3B transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0278849%22%3E%3Ci%3Eetfdh%3C%2Fi%3E%3C%2Fa%3E)%3B defects in human ETFB are a cause of multiple acyl-CoA dehydrogenase deficiency (MADD)
chr3	126886	128657	+	DDB_G0277993	DDB_G0277993	importins function in nuclear protein import%2C however%2C this protein does not contain the N-terminal importin beta binding domain (IBB domain)
chr3	130346	140572	+	DDB_G0277997	DDB_G0277997	NA
chr3	140895	142743	-	DDB_G0277879	ugpB	required for development and differentiation
chr3	144948	146199	-	DDB_G0277999	DDB_G0277999	sulfurates the molybdenum cofactor%2C which is essential for xanthine dehydrogenase and aldehyde oxidase
chr3	146554	146946	-	DDB_G0278001	DDB_G0278001	NA
chr3	147404	148477	-	DDB_G0278003	DDB_G0278003	NA
chr3	151993	153090	-	DDB_G0278005	DDB_G0278005	NA
chr3	153604	153810	-	DDB_G0278007	DDB_G0278007	NA
chr3	154173	155011	+	DDB_G0278009	racN	NA
chr3	155490	156262	+	DDB_G0278011	racQ	NA
chr3	156515	161593	+	DDB_G0294575	DDB_G0294575	NA
chr3	162120	162377	-	DDB_G0278013	DDB_G0278013	NA
chr3	164355	167062	-	DDB_G0278015	DDB_G0278015	NA
chr3	167304	167864	-	DDB_G0278017	DDB_G0278017	NA
chr3	168687	170015	+	DDB_G0304475	DDB_G0304475	NA
chr3	170689	172404	+	DDB_G0278021	DDB_G0278021	NA
chr3	172946	173351	-	DDB_G0278023	mrpl33	protein component of the mitochondrial large ribosomal subunit
chr3	174453	175235	+	DDB_G0278025	DDB_G0278025	NA
chr3	175913	176563	+	DDB_G0278027	snrpD1	NA
chr3	176737	178182	-	DDB_G0278029	DDB_G0278029	NA
chr3	178451	179303	-	DDB_G0278031	DDB_G0278031	NA
chr3	179912	182605	-	DDB_G0277909	cbpP	NA
chr3	183263	183872	-	DDB_G0295721	naa50	highly conserved protein%3B ortholog of human NAA50 and yeast Mak3
chr3	184302	185796	+	DDB_G0278037	sahA_ps	putative pseudogene%3B similar to S-adenosyl-L-homocysteine hydrolase sahA
chr3	186227	187053	+	DDB_G0278039	rpb8	subunit common to RNA polymerases I%2C II and III%3B ortholog of S. cerevisiae RPB8
chr3	187950	189871	-	DDB_G0277855	fimA	calcium-regulated actin bundling protein%3B binds F-actin%3B enriched in gametes
chr3	190215	191792	+	DDB_G0278045	DDB_G0278045	NA
chr3	191972	193220	-	DDB_G0278047	DDB_G0278047	similar to fungal CorA transporter proteins
chr3	193898	194222	+	DDB_G0278049	DDB_G0278049	NA
chr3	194635	197654	-	DDB_G0278051	elmoA	associates with myosin II and negatively regulates actin polymerization%2C thus involved in the coordination of phagocytosis and cell migration
chr3	198473	200536	-	DDB_G0278053	ilvB	catalyzes the reaction:  2 pyruvate %3C%3D%3E 2-acetolactate %2B CO%3Csub%3E2%3C%2Fsub%3E
chr3	200995	201929	-	DDB_G0294617	DDB_G0294617	weakly similar to estrogen receptor binding protein
chr3	202964	205644	+	DDB_G0277913	gefJ	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr3	206243	207086	+	DDB_G0278057	arrL	NA
chr3	207407	209554	-	DDB_G0278059	DDB_G0278059	similar to the human acetyl-coenzyme A transporter 1%3B contains 10 putative transmembrane domains
chr3	209901	211233	-	DDB_G0278061	tmem115	contains five transmembrane domains
chr3	211823	214784	+	DDB_G0278063	DDB_G0278063	highly similar to H. sapiens LONP1 and S. cerevisiae PIM1%3B Lon protease family members are often located in the mitochondria%3B there is a second Lon protease in Dictyostelium
chr3	214953	215198	-	DDB_G0278065	DDB_G0278065	contains no functional domains%3B weakly similar to Candida glabrata XP_449244
chr3	216614	217183	+	DDB_G0278067	DDB_G0278067	NA
chr3	221612	224223	+	DDB_G0278069	gacII	NA
chr3	225002	227095	+	DDB_G0278591	DDB_G0278591	NA
chr3	227597	228670	-	DDB_G0278071	DDB_G0278071	NA
chr3	229027	232659	-	DDB_G0278073	DDB_G0278073	NA
chr3	233703	234872	+	DDB_G0278075	DDB_G0278075	NA
chr3	235235	237989	-	DDB_G0278077	crtf	required for expression of aggregation genes
chr3	240471	242531	+	DDB_G0278593	exdl2B	very similar to mammalian exonuclease 3%27-5%27 domain-like-containing protein 2 (EXDL2)%3B the downstream %3Ci%3EDictyostelium%3C%2Fi%3E gene is very similar
chr3	242964	245120	+	DDB_G0278079	exdl2A	very similar to mammalian exonuclease 3%27-5%27 domain-like-containing protein 2 (EXDL2)%3B the upstream %3Ci%3EDictyostelium%3C%2Fi%3E gene is very similar
chr3	246720	247623	+	DDB_G0277863	pdiA	NA
chr3	248036	249141	-	DDB_G0278081	DDB_G0278081_ps	putative pseudogene%3B acetyl-CoA synthetase fragment
chr3	249687	252103	-	DDB_G0278083	DDB_G0278083	highly similar to acetyl-CoA synthetase%2C which condenses acetate and CoA to acetyl-coA  
chr3	252381	255025	-	DDB_G0277849	dymA	NA
chr3	256195	257992	-	DDB_G0278087	DDB_G0278087_ps	putative pseudogene%2C containing a partial protein kinase domain and a partial ankyrin repeat
chr3	258121	259280	-	DDB_G0278091	DDB_G0278091	NA
chr3	259686	262139	-	DDB_G0278093	DDB_G0278093	NA
chr3	262493	263754	-	DDB_G0278095	mecr	ortholog of the mammalian MECR and S. cerevisiae ETR1%2C a mitochondrial 2-enoyl thioester reductase that belongs to the zinc-containing alcohol dehydrogenase family
chr3	264255	270651	+	DDB_G0278097	DDB_G0278097	NA
chr3	270787	271068	-	DDB_G0278099	DDB_G0278099_ps	putative pseudogene%2C kinase motif-containing (KMC)
chr3	272535	273185	-	DDB_G0278101	cnrO	identified as a suppressor of smlA null mutant cnr15
chr3	273541	275022	-	DDB_G0277885	gnd	catalyzes the reaction 6-phospho-D-gluconate %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %3C%3D%3E D-ribulose 5-phosphate %2B CO%3Csub%3E2%3C%2Fsub%3E %2B NADPH
chr3	276805	278197	+	DDB_G0277889	amtB	similar to Arabidopsis AMT1%2C involved in transporting ammonia in the environment into the cell%3B contains 11 transmembrane domains
chr3	278742	279896	+	DDB_G0278103	DDB_G0278103	NA
chr3	280166	282713	-	DDB_G0278105	DDB_G0278105	highly similar to HNRNPL%2C a heterogeneous ribonucleoprotein that plays a role in pre-mRNA splicing
chr3	283161	283844	+	DDB_G0278107	DDB_G0278107	catalyzes the reaction pyridoxamine 5%27-phosphate %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3D pyridoxal 5%27-phosphate %2B NH%3Csub%3E3%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr3	283984	286396	-	DDB_G0295723	DDB_G0295723	NA
chr3	287423	288337	-	DDB_G0278597	DDB_G0278597	NA
chr3	288911	291499	-	DDB_G0278109	tgrA_ps5	putative pseudogene%3B immunoglobulin E-set family gene
chr3	292760	293617	-	DDB_G0277827	cafA	%3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with the subunits (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0287815%22%3EDDB_G0287815%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269800%22%3EDDB_G0269800%3C%2Fa%3E) of the chromatin assembly factor 1 (CAF1)
chr3	294308	294864	-	DDB_G0278111	DDB_G0278111	putative ortholog of programmed cell death protein 5 (TFAR19) that may function in apoptosis
chr3	295249	295926	-	DDB_G0278113	DDB_G0278113	similar to protein-tyrosine phosphatases%2C but probably not catalytically active due to lack of conservation of active site residues%3B similar to human PTPLA (protein-tyrosine phosphatase-like member A)%3B contains 4 putative transmembrane domains
chr3	296602	297542	+	DDB_G0278115	netD	conserved protein also known as Tmem53%3B contains 1 putative transmembrane domain
chr3	297893	302229	+	DDB_G0278601	DDB_G0278601	NA
chr3	302308	303514	-	DDB_G0277921	sigE	regulated by the MADS-box transcription factor SrfA during development%3B contains one transmembrane domain
chr3	304397	306034	-	DDB_G0277825	arcA	component of the Dictyostelium Arp2%2FArp3 complex
chr3	306850	307279	+	DDB_G0278117	sec61b	beta subunit of the SEC61 complex (composed of %3Ca href%3D%22%2Fgene%2FDDB_G0278885%22%3ESec61a%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0278117%22%3ESec61b%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0287777%22%3ESec61g%3C%2Fa%3E) involved in protein targeting to the membrane
chr3	307681	309046	-	DDB_G0278119	DDB_G0278119	NA
chr3	309381	310345	-	DDB_G0277881	limC	binds to F-actin%3B contributes to the maintenance of the cortical actin cytoskeleton
chr3	311161	311662	+	DDB_G0278603	DDB_G0278603	NA
chr3	312009	313085	-	DDB_G0295725	DDB_G0295725	conserved prokaryotic protein
chr3	313759	315215	+	DDB_G0278607	mvd	catalyzes the reaction ATP %2B (R)-5-diphosphomevalonate %3D ADP %2B phosphate %2B isopentenyl diphosphate %2B CO%3Csub%3E2%3C%2Fsub%3E in steroid biosynthesis
chr3	316046	317868	+	DDB_G0278609	DDB_G0278609	NA
chr3	318473	321112	+	DDB_G0278611	DDB_G0278611	NA
chr3	321235	325752	-	DDB_G0278121	DDB_G0278121	NA
chr3	326427	326761	-	DDB_G0278123	DDB_G0278123	NA
chr3	327348	329843	-	DDB_G0278125	DDB_G0278125	NA
chr3	330250	331290	+	DDB_G0277877	uglA	DNA repair enzyme that excises uracil residues from the DNA which can arise from misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
chr3	332007	334836	+	DDB_G0277915	gefI	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr3	335063	335396	-	DDB_G0278127	DDB_G0278127	NA
chr3	335988	337534	-	DDB_G0278131	DDB_G0278131_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0278133%22%3EDDB_G0278133%3C%2Fa%3E
chr3	338266	339830	-	DDB_G0278133	DDB_G0278133	NA
chr3	340292	341762	-	DDB_G0278137	DDB_G0278137_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0278133%22%3EDDB_G0278133%3C%2Fa%3E
chr3	342260	342760	-	DDB_G0278139	DDB_G0278139_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0278133%22%3EDDB_G0278133%3C%2Fa%3E
chr3	343671	346615	-	DDB_G0278141	vps11	NA
chr3	347205	353709	+	DDB_G0278143	DDB_G0278143	NA
chr3	354814	358184	+	DDB_G0278147	gxcW	NA
chr3	358498	361472	-	DDB_G0278613	DDB_G0278613	N-terminus similar to matrilin%2C a vertebrate extracellular matrix protein expressed in cartilage%3B C-terminus similar to other Dictyostelium EGF repeat-containing proteins%3B contains 11 EGF (epidermal growth factor) repeats
chr3	364618	368104	+	DDB_G0277861	patA	P-type ATPase that is up-regulated in calcium-adapted cells%3B contains 10 predicted transmembrane domains
chr3	369004	372051	+	DDB_G0278617	DDB_G0278617	NA
chr3	372488	373942	-	DDB_G0278151	DDB_G0278151	NA
chr3	374402	375450	-	DDB_G0278153	tmem111	conserved eukaryotic protein
chr3	376116	376878	+	DDB_G0278155	mai	catalyzes the reaction 4-maleylacetoacetate %3C%3D%3E 4-fumarylacetoacetate
chr3	377175	377835	+	DDB_G0278157	sdhD	catalyzes the reaction succinate %2B ubiquinone %3D fumarate %2B ubiquinol%3B cytochrome b small subunit%2C contains 3 transmembrane domains
chr3	378150	379977	-	DDB_G0278159	pssA	catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine%3B mammals have two similar phosphatidylserine synthases%2C PTDSS1 and PTDSS2%2C while Dictyostelium contains one%2C which is an ortholog of PTDSS2%3B contains 9 putative transmembrane domains
chr3	381607	383318	+	DDB_G0277865	ptpB	NA
chr3	385354	387534	+	DDB_G0278161	DDB_G0278161	members of the multi antimicrobial extrusion (MATE) family function as drug%2Fsodium antiporters and are found in bacteria%2C archaea and eukaryotes%3B these proteins are predicted to have 12 alpha-helical transmembrane regions
chr3	387740	388320	-	DDB_G0278163	DDB_G0278163	contains a conserved TM2 domain%2C a pair of transmembrane alpha helices connected by a short linker
chr3	389147	389628	-	DDB_G0349267	tgrA_ps8	putative pseudogene%3B fragment of immunoglobulin E-set family genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0291622%22%3E%3Ci%3EtgrA1%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0291666%22%3E%3Ci%3EtgrA2%3C%2Fi%3E%3C%2Fa%3E
chr3	389635	389859	+	DDB_G0349268	tgrA_ps9	putative pseudogene%3B fragment of immunoglobulin E-set family genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0291622%22%3E%3Ci%3EtgrA1%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0291666%22%3E%3Ci%3EtgrA2%3C%2Fi%3E%3C%2Fa%3E
chr3	391115	391267	+	DDB_G0278167	DDB_G0278167	highly similar to a part of DDB_G0291514%2C an immunoglobulin E-set domain-containing protein%3B however much shorter (other members of the family are between 850 and 100 amino acids in length)
chr3	391453	392277	-	DDB_G0278169	DDB_G0278169	NA
chr3	393144	395891	+	DDB_G0278171	DDB_G0278171	NA
chr3	395988	397646	-	DDB_G0278173	DDB_G0278173	NA
chr3	398692	400297	+	DDB_G0278177	DDB_G0278177	NA
chr3	400484	402497	-	DDB_G0278179	DDB_G0278179	contains two myb domains%3B similar to Arabidopsis thaliana DNAJ heat shock N-terminal domain-containing protein (NP_187752.1) and Mus musculus zuotin related factor 2 (NP_033610.1)
chr3	405756	408648	+	DDB_G0278181	DDB_G0278181	NA
chr3	408831	410742	-	DDB_G0278183	DDB_G0278183	NA
chr3	412650	414044	+	DDB_G0277903	cotE	contains cysteine-rich and mucin-like repeats%3B contains a signal peptide such that the first 17 amino acids are cleaved from the mature protein%3B expressed in late culmination
chr3	416548	422805	+	DDB_G0295727	DDB_G0295727	amino terminus is similar to spore coat proteins cotE%2FSP65 and cotD%2FSP75%3B serine and glycine rich%3B the central region contains repeats of the sequence GTSTT or GRSTT%3B contains a predicted signal peptide and at least 18 transmembrane domains
chr3	423737	426046	+	DDB_G0278189	ints11	ortholog of integrator complex subunit 1%2C component of a multiprotein mediator of small nuclear RNA processing
chr3	426271	427288	+	DDB_G0278191	dak	catalyzes the reaction ATP %2B deoxyadenosine %3D ADP %2B dAMP
chr3	427974	430638	+	DDB_G0278621	DDB_G0278621	NA
chr3	430729	431733	-	DDB_G0278623	DDB_G0278623	NA
chr3	432237	435322	+	DDB_G0278625	DDB_G0278625	NA
chr3	435839	439528	-	DDB_G0278627	DDB_G0278627	contains 2 coiled-coil domains%3B similar to D. purpureum protein
chr3	439645	440608	+	DDB_G0277899	DDB_G0277899	NA
chr3	441220	442067	-	DDB_G0277869	rac1A	NA
chr3	444626	446858	+	DDB_G0278193	DDB_G0278193	ortholog of the asparagine synthetase domain containing protein 1%2C conserved from yeast to human
chr3	447655	448305	+	DDB_G0278195	DDB_G0278195	NA
chr3	448708	454535	-	DDB_G0278197	DDB_G0278197	NA
chr3	459553	461950	+	DDB_G0278629	DDB_G0278629	NA
chr3	462648	464104	+	DDB_G0278631	DDB_G0278631	putative ortholog of H. sapiens SLC35D2%2C UDP-N-acetylglucosamine%2FUDP-glucose%2FGDP-mannose transporter%3B contains 10 putative transmembrane domains
chr3	464388	466406	+	DDB_G0278199	DDB_G0278199	NA
chr3	467909	470077	+	DDB_G0277873	sqpA	cAMP inducible Gene
chr3	470480	470827	-	DDB_G0278201	DDB_G0278201	NA
chr3	471533	473001	+	DDB_G0278203	xrcc4	putative ortholog of XRCC4%2C which is involved in double-strand break repair%2C including V(D)J recombination in T-cell receptor genes%3B forms a complex with DNA ligase IV
chr3	473374	473946	-	DDB_G0278205	eIF1a	EIF1AX (eukaryotic initiation factor 1A%2C X-linked) and EIF1AY (eukaryotic initiation factor 1A%2C Y-linked) homolog
chr3	475574	477682	+	DDB_G0278209	DDB_G0278209	NA
chr3	477809	479848	-	DDB_G0278211	DDB_G0278211	NA
chr3	481110	482678	+	DDB_G0278213	DDB_G0278213	NA
chr3	484147	490075	+	DDB_G0278215	DDB_G0278215	contains a predicted signal sequence and 7 putative transmembrane domains%3B conserved in Dictyostelium and Polysphondylium
chr3	491519	492327	+	DDB_G0278217	rsmK	NA
chr3	492709	494218	-	DDB_G0278219	DDB_G0278219	NA
chr3	495104	495607	+	DDB_G0278221	DDB_G0278221_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr3	498291	499717	+	DDB_G0277831	carD	low affinity cAMP receptor%3B belongs to the serpentine%2FG-protein coupled receptor family
chr3	499808	501412	-	DDB_G0278719	DDB_G0278719	NA
chr3	501817	502425	-	DDB_G0278717	rsmG	NA
chr3	504442	506079	+	DDB_G0277829	carC	high affinity cAMP receptor%3B belongs to the serpentine%2FG-protein coupled receptor family
chr3	506205	508541	+	DDB_G0278633	DDB_G0278633_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr3	506383	506465	+	DDB_G0295011	tRNA-Tyr-GUA-4	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr3	509241	509610	+	DDB_G0278225	hbx7	NA
chr3	509789	511581	-	DDB_G0278227	DDB_G0278227	NA
chr3	512537	515209	-	DDB_G0278229	DDB_G0278229	NA
chr3	515488	515895	-	DDB_G0278231	DDB_G0278231	NA
chr3	516517	517431	+	DDB_G0278233	DDB_G0278233	NA
chr3	517463	519124	-	DDB_G0294557	ctxC	similar to the cortexillins%2C actin-bundling proteins of the alpha-actinin%2Fspectrin superfamily
chr3	519532	521406	-	DDB_G0278635	DDB_G0278635	similar to mammalian ribonuclease%2Fangiogenesis inhibitor proteins
chr3	523540	525517	-	DDB_G0278235	DDB_G0278235	NA
chr3	525688	531677	-	DDB_G0277845	dhkB	NA
chr3	533251	534784	-	DDB_G0278239	DDB_G0278239	NA
chr3	535599	538688	-	DDB_G0278639	clcD	CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles%3B they assemble to form homo-dimers
chr3	539874	541072	+	DDB_G0278241	tcea1	general transcription elongation factor TFIIS%2C enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites
chr3	541492	545240	-	DDB_G0278243	rliB	 repressed after %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection%3B contains a signal peptide%3B similar to %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0273257%22%3E%3Ci%3EcomF%3C%2Fi%3E%3C%2Fa%3E
chr3	546702	548036	-	DDB_G0278641	DDB_G0278641_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	549066	549136	+	DDB_G0295013	tRNA-His-GUG-6	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr3	551038	551810	+	DDB_G0278643	trappc5	homolog of human TRAPPC5%2C a component of the multisubunit TRAPP (transport protein particle) complex which may play a role in vesicular transport from endoplasmic reticulum to Golgi
chr3	552139	554805	+	DDB_G0278247	DDB_G0278247	NA
chr3	554945	555789	+	DDB_G0278249	DDB_G0278249	NA
chr3	558488	563918	+	DDB_G0277853	ecmA	composed of approx. 70 copies of a 24-amino-acid cysteine-rich repeat
chr3	565585	566035	-	DDB_G0278251	DDB_G0278251_ps	putative pseudogene%3B fragment%2C similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0281839%22%3EDDB_G0281839%3C%2Fa%3E
chr3	566464	568173	-	DDB_G0278253	DDB_G0278253	NA
chr3	568794	570338	-	DDB_G0278255	DDB_G0278255	NA
chr3	571285	572943	-	DDB_G0278257	DDB_G0278257	similar to human BROX%3B contains one BRO1 domain 
chr3	573780	576993	+	DDB_G0278259	manB	NA
chr3	577308	579437	+	DDB_G0278261	DDB_G0278261	similar to the H. sapiens proton myo-inositol cotransporter SLC2A13%3B contains 10 putative transmembrane domains
chr3	579706	580766	-	DDB_G0278263	rpa12	component of the RNA polymerase I complex%3B ortholog of S. cerevisiae RPA12
chr3	581627	583695	+	DDB_G0278265	DDB_G0278265	NA
chr3	586381	589126	+	DDB_G0278267	DDB_G0278267	NA
chr3	589784	592434	+	DDB_G0277905	snfA	CAMKL family protein kinase%3B catalytic subunit of the AMP-activated protein kinase (AMPK) complex%3B similar to SNF1 kinases and AMPK%3B experiments in Dictyostelium show that AMPK signaling plays an important role in mitochondrial disease.
chr3	593095	594230	+	DDB_G0278269	DDB_G0278269	NA
chr3	594341	596822	-	DDB_G0278645	DDB_G0278645	similar to extracellular matrix proteins
chr3	598613	599289	-	DDB_G0349222	DDB_G0349222	NA
chr3	599596	601031	+	DDB_G0278271	DDB_G0278271	NA
chr3	601284	602879	-	DDB_G0278273	ptcF	NA
chr3	603034	603814	-	DDB_G0278275	rpe	catalyzes the reaction D-ribulose 5-phosphate %3C%3D%3E D-xylulose 5-phosphate
chr3	604573	605887	+	DDB_G0277835	cspA	NA
chr3	606213	607054	-	DDB_G0278277	mdm12	similar to yeast proteins of the MDM12 family (mitochondrial distribution and morphology protein 12)%3B S. cerevisiae MDM12 is a component of the endoplasmic reticulum-mitochondria encounter structure%2C which is essential for maintaining the structure of mitochondria
chr3	607477	608249	+	DDB_G0277917	mlcD	NA
chr3	608653	609434	-	DDB_G0277833	cofA	15 kDa protein with actin filament severing activity
chr3	610480	611752	-	DDB_G0278279	DDB_G0278279	NA
chr3	612467	613676	-	DDB_G0278647	DDB_G0278647	contains structural similarity to terpenoid synthase domain
chr3	614554	615842	-	DDB_G0278281	DDB_G0278281	NA
chr3	616133	618179	-	DDB_G0278283	fol1	multifunctional enzyme of the folic acid biosynthesis pathway%2C has dihydropteroate synthetase%2C dihydro-6-hydroxymethylpterin pyrophosphokinase%2C and dihydroneopterin aldolase domains
chr3	618891	622611	-	DDB_G0278285	copB2	contains six WD40 repeats%3B beta prime subunit of the coatomer complex essential for the secretory pathway
chr3	623186	623368	-	DDB_G0278287	iliE_ps	putative pseudogene%3B small fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0273157%22%3E%3Ci%3EiliE-1%3C%2Fi%3E%3C%2Fa%3E
chr3	625261	627925	+	DDB_G0278289	fslO	has similarity to G-protein-coupled receptors%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr3	628601	632830	+	DDB_G0278291	DDB_G0278291	NA
chr3	632971	636359	-	DDB_G0278293	ileS	catalyzes the reaction ATP %2B L-isoleucine %2B tRNAIle %3D AMP %2B diphosphate %2B L-isoleucyl-tRNAIle
chr3	636762	637763	+	DDB_G0278649	iliK	belongs to a superfamily of metalloenzymes%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr3	638585	639322	+	DDB_G0278295	DDB_G0278295	contains one ML (MD-2-related lipid recognition) domain%3B similar to fungal proteins of the NPC2 family%3B contains a predicted signal peptide
chr3	639451	640653	-	DDB_G0278297	DDB_G0278297	NA
chr3	644203	646306	+	DDB_G0278299	DDB_G0278299	NA
chr3	647938	651814	+	DDB_G0278301	DDB_G0278301	NA
chr3	652045	655289	-	DDB_G0278303	DDB_G0278303_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr3	655951	659720	-	DDB_G0278651	manE	NA
chr3	660402	664359	-	DDB_G0278653	manD	NA
chr3	665995	667855	+	DDB_G0278309	sslA2	there is an identical gene on chromosome 4%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284335%22%3E%3Ci%3EsslA1%3C%2Fi%3E%3C%2Fa%3E
chr3	668576	671801	-	DDB_G0278311	DDB_G0278311	similar to myotubularin%2C a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3%2C5)-bi-phosphate
chr3	672611	673477	+	DDB_G0278655	DDB_G0278655	NA
chr3	673736	675487	+	DDB_G0278313	DDB_G0278313	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr3	676729	682811	+	DDB_G0278657	DDB_G0278657_ps	putative pseudogene%2C similar to DDB_G0293286 and DDB_G0293288
chr3	683079	685187	+	DDB_G0278315	DDB_G0278315	contains 5 predicted transmembrane domains
chr3	686928	688622	+	DDB_G0278317	mybF	contains one Myb DNA-binding domain
chr3	689224	692344	+	DDB_G0278321	gtf3C3	NA
chr3	692443	695001	-	DDB_G0278659	DDB_G0278659	NA
chr3	695788	700246	-	DDB_G0278661	DDB_G0278661	contains a putative nitrous oxide reductase domain
chr3	701606	704101	-	DDB_G0278663	DDB_G0278663	contains two coiled-coil domains
chr3	704452	704660	+	DDB_G0278323	DDB_G0278323	NA
chr3	705714	707567	+	DDB_G0278325	DDB_G0278325	NA
chr3	707798	709539	+	DDB_G0278327	DDB_G0278327	NA
chr3	709648	710709	-	DDB_G0278329	DDB_G0278329	NA
chr3	711190	713754	+	DDB_G0278331	DDB_G0278331	NA
chr3	713907	716110	-	DDB_G0278333	DDB_G0278333	NA
chr3	716610	717246	-	DDB_G0278335	snrpC	a component of the U1 snRNP involved in the initiation and regulation of mRNA splicing
chr3	717847	718532	-	DDB_G0278337	DDB_G0278337	contains no functional domains and is not similar to any other protein
chr3	719660	721905	+	DDB_G0278339	DDB_G0278339	NA
chr3	722601	724035	-	DDB_G0278341	DDB_G0278341	highly similar to ACLY%2C which catalyzes the reaction ADP %2B phosphate %2B acetyl-CoA %2B oxaloacetate %3C%3D%3E ATP %2B citrate %2B CoA
chr3	726196	728064	+	DDB_G0278345	acly	catalyzes the reaction ADP %2B phosphate %2B acetyl-CoA %2B oxaloacetate %3C%3D%3E ATP %2B citrate %2B CoA
chr3	729623	730084	+	DDB_G0278347	DDB_G0278347	NA
chr3	731119	732534	+	DDB_G0278349	tra2	similar to the conserved Tra2 proteins (including human TRA2A%2C TRA2B and SFRS10) that have splicing regulatory function%3B involved in sex-determination in Drosophila
chr3	734436	737543	+	DDB_G0278351	DDB_G0278351	NA
chr3	737677	739535	-	DDB_G0278353	smu1	conserved protein that interacts with dynein and dynactin and may participate in targeting cytoplasmic dynein to the microtubule plus ends
chr3	739670	741739	+	DDB_G0278355	DDB_G0278355	NA
chr3	742074	742494	-	DDB_G0278357	DDB_G0278357	NA
chr3	743092	744234	-	DDB_G0277867	rab1B	similar to rab1
chr3	746082	749671	+	DDB_G0277841	ctr9	component of the conserved Paf1 complex%2C a multifunctional complex%2C involved in histone methylation and plays a role in RNA elongation and processing%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Fctr9%22%3Ecommunity annotation%3C%2Fa%3E
chr3	749797	752376	-	DDB_G0278359	DDB_G0278359	NA
chr3	753135	757040	-	DDB_G0278665	DDB_G0278665	member of the TKL (tyrosine kinase-like) group of protein kinases
chr3	758682	759224	+	DDB_G0278667	DDB_G0278667	NA
chr3	759575	760889	+	DDB_G0278361	DDB_G0278361_ps	putative pseudogene%2C very similar to DDB_G0278909%2C an ARMK family protein
chr3	761869	762570	+	DDB_G0278363	DDB_G0278363	NA
chr3	762818	762961	+	DDB_G0278365	DDB_G0278365	NA
chr3	766301	768775	-	DDB_G0278367	DDB_G0278367	similar to DNA polymerase epsilon subunit B in yeast and vertebrates%3B thought to be involved in DNA replication%2C DNA repair%2C and cell-cycle checkpoint control in eukaryotes
chr3	768975	770144	+	DDB_G0278369	DDB_G0278369	NA
chr3	770499	770858	-	DDB_G0278371	spc1	ortholog of the conserved microsomal signal peptidase 12 kDa subunit%3B the signal peptidase complex is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum%3B contains a putative signal peptide and one transmembrane domain
chr3	771365	773623	-	DDB_G0278373	DDB_G0278373	at the N-terminus very similar to human ATPBD4 (ATP binding domain 4)%2C also similar to plant and fungal endoribonuclease L-PSP family proteins
chr3	776296	778895	+	DDB_G0277857	helB2	conserved RNA helicase%3B  S. cerevisiae ortholog PRP28 is involved in RNA isomerization at the 5%27 splice site
chr3	779475	780824	+	DDB_G0278375	DDB_G0278375	NA
chr3	781169	782398	-	DDB_G0278669	DDB_G0278669	NA
chr3	782698	784629	-	DDB_G0278377	DDB_G0278377	NA
chr3	784969	786624	-	DDB_G0278671	DDB_G0278671	NA
chr3	788140	789126	-	DDB_G0278673	maf1	negative regulator of RNA polymerase III%2C homolog of H. sapiens and S. cerevisiae MAF1
chr3	789665	791723	-	DDB_G0278675	DDB_G0278675	NA
chr3	792608	794195	+	DDB_G0277901	apm3	similar to the human mu3A
chr3	795514	798263	+	DDB_G0278379	bzpD	NA
chr3	800738	802121	-	DDB_G0278381	gacA	NA
chr3	803175	803642	+	DDB_G0278383	DDB_G0278383	NA
chr3	803909	804802	-	DDB_G0278677	DDB_G0278677	NA
chr3	805261	806859	-	DDB_G0278679	cyp513F1	NA
chr3	810765	811001	+	DDB_G0278385	DDB_G0278385	NA
chr3	811383	812402	-	DDB_G0278387	bloc1s2	ortholog of human BLOC1S2%2C a component of the BLOC-1 complex that is required for normal biogenesis of lysosome-related organelles
chr3	814663	815380	+	DDB_G0278389	rsmF	NA
chr3	815812	816438	+	DDB_G0278391	DDB_G0278391	contains a predicted signal peptide
chr3	817359	818852	+	DDB_G0278393	DDB_G0278393	NA
chr3	819227	821289	-	DDB_G0278395	DDB_G0278395	NA
chr3	821871	822323	+	DDB_G0278399	DDB_G0278399	NA
chr3	822687	824101	+	DDB_G0278401	cprH	belongs to the peptidase family C1%2C sub-family C1A (papain family%2C clan CA)%3B repressed after %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr3	825274	826184	+	DDB_G0278403	rsmH	NA
chr3	827063	829140	+	DDB_G0278681	DDB_G0278681	NA
chr3	830272	832065	+	DDB_G0278405	DDB_G0278405	NA
chr3	833181	836091	+	DDB_G0278407	DDB_G0278407	NA
chr3	836437	838779	-	DDB_G0278409	shkC	member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily%3B contains a C-terminal SH2 (Src homology 2) domain
chr3	839543	840416	+	DDB_G0278683	DDB_G0278683	NA
chr3	845743	848931	+	DDB_G0277871	rsc12	NA
chr3	849816	851130	+	DDB_G0278411	DDB_G0278411	NA
chr3	851201	851894	-	DDB_G0278413	ppcdc	decarboxylates N-[(R)-4%27-phosphopantothenoyl]-L-cysteine to pantotheine 4%27-phosphate
chr3	852176	854714	-	DDB_G0278685	clmA	clathrin adaptor protein that regulates contractile vacuole size and involved in the response to osmotic stress%3B interacts with Vamp7B  and retrieves Vamp7B from the contractile vacuole%3B ortholog of H. sapiens SNAP91
chr3	855258	856931	-	DDB_G0277919	eRF3	NA
chr3	857716	858660	+	DDB_G0278415	DDB_G0278415	similar to human ABHD11 (abhydrolase domain-containing protein 11)
chr3	859128	863604	+	DDB_G0278417	xacB	NA
chr3	863855	864415	+	DDB_G0278419	ddiA_ps	putative pseudogene%3B similar to the ribonuclease T2 %3Ca href%3D%22%2Fgene%2FDDB_G0281293%22%3EddiA%3C%2Fa%3E
chr3	865177	865611	+	DDB_G0278421	DDB_G0278421	NA
chr3	866013	866453	+	DDB_G0278423	DDB_G0278423	NA
chr3	866714	870080	-	DDB_G0278425	DDB_G0278425	NA
chr3	870597	871423	+	DDB_G0278427	DDB_G0278427	similar to human METTL10 (methyltransferase-like protein 10)
chr3	871775	872149	-	DDB_G0278429	rps20	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S20 homolog
chr3	872674	874217	-	DDB_G0278431	DDB_G0278431	NA
chr3	875590	877535	+	DDB_G0278433	DDB_G0278433	contains an N-terminal RRM motif and a CCHC-type zinc finger domain in the C-terminal half
chr3	877848	880508	-	DDB_G0278435	DDB_G0278435	ortholog of H. sapiens SPATA5 (spermatogenesis associated 5) and S. cerevisiae AFG2 (ATPase family gene 2)
chr3	880882	881322	-	DDB_G0278437	DDB_G0278437	NA
chr3	881959	882399	-	DDB_G0278439	DDB_G0278439	NA
chr3	883102	884257	-	DDB_G0278441	DDB_G0278441	NA
chr3	885094	886826	+	DDB_G0278443	DDB_G0278443	NA
chr3	887014	890500	+	DDB_G0278687	pigO	putative transferase involved in GPI biosynthesis%3B functions with PigF to transfer ethanolamine phosphate to the third mannose of GPI (glycosylphosphatidylinositol)
chr3	890638	893525	-	DDB_G0278445	mpl3	NA
chr3	896854	897725	+	DDB_G0278449	rsmC	NA
chr3	898275	900389	+	DDB_G0278451	DDB_G0278451	NA
chr3	901380	904104	+	DDB_G0278453	DDB_G0278453	contains 5 coiled-coil domains%3B highly repetitive%2C glutamine and glutamic acid-rich protein
chr3	904324	905523	-	DDB_G0278455	DDB_G0278455	NA
chr3	907158	908849	+	DDB_G0278457	ndrA	member of the AGC kinases%2C NDR group%3B localizes to centrosomes and to the spindle during prometaphase and is involved in phagocytosis
chr3	909148	909474	-	DDB_G0278459	DDB_G0278459	similar to human C6orf57
chr3	910604	913450	+	DDB_G0278461	DDB_G0278461	NA
chr3	913723	915845	+	DDB_G0278463	DDB_G0278463	NA
chr3	916080	916256	-	DDB_G0278465	DDB_G0278465	NA
chr3	918286	918465	-	DDB_G0278467	DDB_G0278467	NA
chr3	919657	922497	-	DDB_G0277823	alaS	catalyzes the reaction ATP %2B L-alanine %2B tRNAAla %3D AMP %2B diphosphate %2B L-alanyl-tRNAAla
chr3	923436	923743	-	DDB_G0278689	DDB_G0278689	NA
chr3	924371	926602	+	DDB_G0278469	DDB_G0278469	NA
chr3	926878	928461	-	DDB_G0278471	DDB_G0278471	NA
chr3	929409	931627	-	DDB_G0278473	DDB_G0278473	NA
chr3	932374	934337	+	DDB_G0278475	DDB_G0278475	NA
chr3	934441	935515	-	DDB_G0278477	sarB	weakly similar to budding yeast Sar1%2C a 21 kDa GTP- binding protein involved in vesicular transport between the endoplasmic reticulum and the Golgi
chr3	936199	937743	+	DDB_G0278479	DDB_G0278479	NA
chr3	937883	939277	-	DDB_G0278691	DDB_G0278691	NA
chr3	939361	941535	-	DDB_G0278693	DDB_G0278693	NA
chr3	942210	945957	-	DDB_G0277887	dhkK	contains a response regulator receiver domain found in two-component signal transduction systems and six predicted transmembrane domains
chr3	950150	951676	+	DDB_G0278481	iliN	conserved protein%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr3	951936	954731	-	DDB_G0278483	ngap	NA
chr3	959760	962183	+	DDB_G0278487	DDB_G0278487	similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases%3B belongs to the CMGC group of protein kinases
chr3	962952	964582	-	DDB_G0278489	DDB_G0278489	NA
chr3	965453	966959	-	DDB_G0278491	DDB_G0278491	NA
chr3	967226	967869	+	DDB_G0278493	DDB_G0278493	similar to S. cerevisiae FAP1 and H. sapiens adrenal gland protein AD-004 (Swiss Prot Q9YD8)
chr3	968065	969744	-	DDB_G0278495	alp	catalyzes the reaction a phosphate monoester %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E an alcohol %2B phosphate%3B exhibits a punctate pattern in immunoflourescence that most likely represents vesicles%3B enzymatic activity is developmentally regulated in a cell type-specific manner
chr3	971318	975668	+	DDB_G0278499	DDB_G0278499	protein phosphatase 2C is a serine%2Fthreonine specific protein phosphatase with broad substrate specificity and dependent on divalent cations (mainly manganese and magnesium) for its activity%3B similar to P. pallidum protein
chr3	976180	978681	+	DDB_G0278501	DDB_G0278501	weakly similar to yeast transmembrane ubiquitin ligase E3 (TUL1) protein%2C involved in ubiquitinating and sorting certain membrane proteins%3B contains 6 predicted transmembrane domains and one additional signal sequence
chr3	979308	980073	+	DDB_G0278503	DDB_G0278503	NA
chr3	980321	981476	+	DDB_G0278505	DDB_G0278505	conserved in bacteria%3B similar to human HEMK1 (hemK methyltransferase family member 1) and S. cerevisiae MTQ1 (mitochondrial N(5)-glutamine methyltransferase MTQ1)
chr3	981524	983660	-	DDB_G0278507	DDB_G0278507	NA
chr3	984753	988653	+	DDB_G0278509	DDB_G0278509	member of the TKL (tyrosine kinase-like) group of protein kinases
chr3	988851	989331	-	DDB_G0278511	DDB_G0278511_ps	putative pseudogene%3B fragment%2C highly similar to neighboring %3Ca href%3D%22%2Fgene%2FDDB_G0278513%22%3EDDB_G0278513%3C%2Fa%3E
chr3	990043	992425	-	DDB_G0278513	DDB_G0278513	NA
chr3	993620	994969	-	DDB_G0278515	DDB_G0278515_ps	putative pseudogene%3B highly similar to neighboring %3Ca href%3D%22%2Fgene%2FDDB_G0278513%22%3EDDB_G0278513%3C%2Fa%3E
chr3	995255	996064	+	DDB_G0278517	DDB_G0278517	NA
chr3	996509	997473	+	DDB_G0277911	mfeB	NA
chr3	997978	998583	+	DDB_G0278519	DDB_G0278519	NA
chr3	999218	999415	+	DDB_G0278695	DDB_G0278695	putative secreted protein%3B contains a predicted signal sequence
chr3	1000143	1000757	+	DDB_G0278697	DDB_G0278697	NA
chr3	1000912	1003638	-	DDB_G0278521	DDB_G0278521	member of the TKL (tyrosine kinase-like) group%2C the MLK (mixed lineage kinase) family%2C and the HH498 subfamily%3B contains an ankyrin repeat
chr3	1004448	1006232	+	DDB_G0278699	DDB_G0278699	contains a weak tweety (tty) domain%2C which is of unknown function
chr3	1006468	1011515	-	DDB_G0277843	DG1105	NA
chr3	1012938	1018512	+	DDB_G0278701	ncapD3	component of the condensin II complex%2C which is involved in physical rigidity of the chromatid axis %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  The involvement of ncapD3 in mitosis in Dicty is supported by its 15-fold  overexpression in a Dicty strain lacking the Dicty retinoblastoma-liked gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E  (Doquang et al%2C in preparation).  Most genes whose products are involved in mitosis or DNA replication are overexpressed in this strain.  This includes all SMC subunits SMC1-SMC6%2C which are overexpressed with factors between 5 and 14-fold. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr3	1018779	1019363	-	DDB_G0278523	DDB_G0278523	NA
chr3	1019968	1021228	-	DDB_G0278525	plaA	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr3	1022106	1025121	+	DDB_G0278527	DDB_G0278527	NA
chr3	1025609	1026276	-	DDB_G0278529	DDB_G0278529	putative 22 kDa peroxisomal membrane protein that may be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane
chr3	1026839	1027765	+	DDB_G0277907	rplP1	NA
chr3	1028305	1033049	-	DDB_G0278531	DDB_G0278531	NA
chr3	1034770	1037737	+	DDB_G0278535	DDB_G0278535	member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family%3B contains an ankyrin repeat region and a SAM (Sterile alpha motif) domain
chr3	1038088	1038630	-	DDB_G0278537	DDB_G0278537	NA
chr3	1039561	1040650	-	DDB_G0278539	rpl5	protein component of the large (60S) ribosomal subunit%3B ribosomal protein L5 homolog
chr3	1041012	1042497	-	DDB_G0278541	DDB_G0278541	MBOAT family protein%2C membrane proteins that contains a variety of acyltransferase enzymes%3B most similar to S. cerevisiae ALE1 and mammalian MBOAT2%3B contains 9 predicted transmembrane domains
chr3	1043259	1044326	+	DDB_G0278543	srpRB	mediates the delivery of nascent secretory proteins to the endoplasmic reticulum by the signal recognition particle (SRP)
chr3	1045240	1045312	+	DDB_G0295015	tRNA-Asn-GUU-10	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr3	1046298	1052275	-	DDB_G0278545	fimC	contains 4 calponin homology (CH) domains%3B two CH domains constitute one actin binding domain
chr3	1052856	1055569	+	DDB_G0278703	gxcII	NA
chr3	1056077	1057365	-	DDB_G0278549	gacB	NA
chr3	1058155	1059582	-	DDB_G0278705	DDB_G0278705	NA
chr3	1060290	1062509	-	DDB_G0278551	DDB_G0278551	NA
chr3	1063899	1066276	+	DDB_G0277847	pdhC	catalyzes the reaction acetyl-CoA %2B dihydrolipoamide %3C%3D%3E CoA %2B S-acetyldihydrolipoamide%3B E2 component of pyruvate dehydrogenase complex which contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0292994%22%3E phdA%3C%2Fa%3E%2C %3Ca href%3D%22 %2Fgene%2FDDB_G0276417%22%3E phdB%3C%2Fa%3E)%2C dihydrolipoamide acetyltransferase (E2%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0277847%22%3E phdC%3C%2Fa%3E) and lipoamide dehydrogenase (E3%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0291648%22%3E lpd)%3C%2Fa%3E.
chr3	1066866	1067468	-	DDB_G0278553	DDB_G0278553	small amoebozoan gene family%3B absent in other organisms
chr3	1071153	1071701	-	DDB_G0278557	DDB_G0278557	small amoebozoan gene family%3B absent in other organisms%3B %3Ca href%3D%22%2Fgene%2FDDB_G0278707%22%3EDDB_G0278707%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0278565%22%3EDDB_G0278565%3C%2Fa%3E%2C and  %3Ca href%3D%22%2Fgene%2FDDB_G0278557%22%3EDDB_G0278557%3C%2Fa%3E encode identical proteins 
chr3	1073057	1073686	-	DDB_G0278559	DDB_G0278559	small amoebozoan gene family%3B absent in other organisms 
chr3	1075082	1075724	-	DDB_G0278561	DDB_G0278561	small amoebozoan gene family%3B absent in other organisms 
chr3	1076940	1077754	-	DDB_G0278563	DDB_G0278563	NA
chr3	1078278	1078829	-	DDB_G0278565	DDB_G0278565	small amoebozoan gene family%3B absent in other organisms%3B %3Ca href%3D%22%2Fgene%2FDDB_G0278707%22%3EDDB_G0278707%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0278565%22%3EDDB_G0278565%3C%2Fa%3E%2C and  %3Ca href%3D%22%2Fgene%2FDDB_G0278557%22%3EDDB_G0278557%3C%2Fa%3E encode identical proteins 
chr3	1079955	1080514	-	DDB_G0278707	DDB_G0278707	small amoebozoan gene family%3B absent in other organisms%3B %3Ca href%3D%22%2Fgene%2FDDB_G0278707%22%3EDDB_G0278707%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0278565%22%3EDDB_G0278565%3C%2Fa%3E%2C and  %3Ca href%3D%22%2Fgene%2FDDB_G0278557%22%3EDDB_G0278557%3C%2Fa%3E encode identical proteins
chr3	1081009	1083771	-	DDB_G0277851	dymB	NA
chr3	1084792	1086368	+	DDB_G0278709	DDB_G0278709	NA
chr3	1086802	1087339	-	DDB_G0278711	nedd8	conserved ubiquitin-like protein%2C which plays an important role in cell cycle control%2C and in embryogenesis in animals
chr3	1087624	1088616	-	DDB_G0278713	prosc	highly similar to mammalian PROSC%2C a homolog of a bacterial gene co-transcribed with proline synthetase
chr3	1089249	1090634	+	DDB_G0278567	DDB_G0278567	catalyzes the reaction NADH %2B 2 ferricytochrome b5 %3D NAD(%2B) %2B H(%2B) %2B 2 ferrocytochrome%3B involved in             desaturation and elongation of fatty acids%2C cholesterol             biosynthesis%2C and drug metabolism 
chr3	1091191	1092112	+	DDB_G0278569	DDB_G0278569	NA
chr3	1092876	1093321	-	DDB_G0278571	DDB_G0278571	conserved protein%3B contains two transmembrane domains
chr3	1094317	1095126	+	DDB_G0278573	DDB_G0278573	this domain is found in several enzymes of the class EC 2.4.2
chr3	1095238	1096776	-	DDB_G0278575	DDB_G0278575	NA
chr3	1097386	1097841	+	DDB_G0278577	DDB_G0278577	contains one putative transmembrane domain%3B contains a predicted signal sequence%3B similar to D. purpureum protein
chr3	1100393	1100445	-	DDB_G0295537	r46	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr3	1101057	1101113	-	DDB_G0295539	r25	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr3	1101587	1101647	-	DDB_G0295541	r47	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr3	1102831	1103518	+	DDB_G0278579	dynE	ortholog of dynactin 5
chr3	1109794	1110546	+	DDB_G0278743	DDB_G0278743	NA
chr3	1111389	1112144	+	DDB_G0278745	DDB_G0278745	NA
chr3	1112773	1112845	-	DDB_G0295167	tRNA-Lys-UUU-13	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr3	1113093	1114781	+	DDB_G0278747	DDB_G0278747	NA
chr3	1114992	1116827	-	DDB_G0278749	DDB_G0278749	NA
chr3	1117749	1118645	+	DDB_G0278751	DDB_G0278751	similar to S. cerevisiae UPF0399 protein YOR287C%2C which may be involved in rRNA-processing and ribosome biosynthesis%3B contains two putative coiled-coil domains
chr3	1118934	1119274	-	DDB_G0278753	cyb5C	cytochrome b5 proteins are membrane bound hemoproteins that function as an electron carrier for several membrane bound oxygenases%2C however%2C this protein seems truncated at the C-terminus and does not contain any transmembrane domain 
chr3	1120346	1122813	-	DDB_G0278755	gacR	NA
chr3	1123519	1127550	-	DDB_G0278757	DDB_G0278757	NA
chr3	1128110	1130593	+	DDB_G0278759	DDB_G0278759	NA
chr3	1131314	1136948	+	DDB_G0278761	DDB_G0278761	highly similar to H. sapiens ZNFX1
chr3	1137106	1137804	-	DDB_G0278763	DDB_G0278763	NA
chr3	1138348	1138995	-	DDB_G0278765	DDB_G0278765	NA
chr3	1139276	1141186	+	DDB_G0278767	DDB_G0278767	contains an N-terminal F-box domain
chr3	1141749	1143269	+	DDB_G0278769	cstf1	component of the CSTF complex%2C which in mammalian  is required for polyadenylation and 3%27-end cleavage of pre-mRNAs
chr3	1143468	1147597	-	DDB_G0278771	DDB_G0278771	NA
chr3	1149897	1151429	-	DDB_G0278773	DDB_G0278773	similar to human VAPA and VAPB%3B defects in VAPB cause amyotrophic lateral sclerosis 8 (ALS8)
chr3	1152307	1152877	+	DDB_G0278775	ube2c	putative ortholog of S. pombe ubc11 and H. sapiens UBE2C%2C involved in the destruction of cyclins during mitosis%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E A role of this gene in cell cycle progression is supported by its sevenfold overexpression in a Dicty strain lacking the Dicty retinoblastoma like gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E (Doquang et al%2C in preparation). This strain overexpresses most genes whose products are involved in mitosis and DNA replication.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr3	1154369	1159209	+	DDB_G0278727	pikA	NA
chr3	1160699	1161599	+	DDB_G0278777	DDB_G0278777_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0273573%22%3EDDB_G0273573%3C%2Fa%3E 
chr3	1161694	1167049	-	DDB_G0278723	gdt1	represses discoidin expression%3B member of the TKL (tyrosine kinase-like) group and the GDT family%3B unlikely to function as a kinase as it does not contain a catalytic aspartate%3B putative transmembrane protein
chr3	1168705	1171255	-	DDB_G0278779	aco2	catalyzes the reaction citrate %3C%3D%3E cis-aconitate %2B H%3Csub%3E2%3C%2Fsub%3EO%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with aco%2C the oxidoreductase%2C or acoA%2C the acyl-CoA oxidase
chr3	1172682	1174440	+	DDB_G0278781	pah	catalyzes the reaction L-phenylalanine %2B tetrahydrobiopterin %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E L-tyrosine %2B 4a-hydroxytetrahydrobiopterin
chr3	1174736	1176055	+	DDB_G0278783	elp4	similar to ELP4%2C subunit of the RNA polymerase II elongator complex
chr3	1176379	1177366	+	DDB_G0278785	DDB_G0278785	NA
chr3	1177436	1178418	-	DDB_G0278787	DDB_G0278787	NA
chr3	1179274	1181013	-	DDB_G0278721	cprD	NA
chr3	1182227	1183696	+	DDB_G0278789	DDB_G0278789	similar to DNAJA3%2C DnaJ homolog subfamily A member 3
chr3	1184009	1185447	-	DDB_G0278791	DDB_G0278791	NA
chr3	1186077	1187040	+	DDB_G0278793	rmd1	required for myosin II cleavage furrow accumulation
chr3	1187328	1189572	-	DDB_G0278739	I6KA	mediates chemotaxis via pleckstrin homology (PH)  domain-PtdIns(3%2C4%2C5)P3 interactions
chr3	1191521	1192327	+	DDB_G0278795	senp8	ortholog of SENP8%2C a conserved protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins
chr3	1192386	1193618	-	DDB_G0278797	DDB_G0278797	NA
chr3	1193824	1195937	+	DDB_G0278935	rad18	RAD18 ortholog%2C a E3 ubiquitin ligase required for postreplicational DNA repair%3B forms a heterodimer with RAD6
chr3	1197002	1203965	+	DDB_G0278731	pgtD	CAZy family GT2%2F4%3B expressed in prespore cells
chr3	1204493	1206040	-	DDB_G0278799	crop	putative RNA binding protein that plays a role in splice site recognition
chr3	1206396	1207886	-	DDB_G0278801	DDB_G0278801	NA
chr3	1208252	1209559	+	DDB_G0278803	dus1l	ortholog of S. cerevisiae DUS1 and the animal DUS1L%3B catalyzes the synthesis of dihydrouridine%2C a modified base found in the D-loop of tRNAs
chr3	1209711	1210757	+	DDB_G0278805	DDB_G0278805	NA
chr3	1213734	1214127	+	DDB_G0278807	DDB_G0278807	contains no functional domains and is not similar to any other protein
chr3	1214678	1217558	+	DDB_G0278937	DDB_G0278937	NA
chr3	1218919	1222296	+	DDB_G0278737	rckA	member of the TKL (tyrosine kinase-like) group%3B contains an RGS (Regulator of G protein Signaling) domain
chr3	1222621	1224150	-	DDB_G0278939	DDB_G0278939	NA
chr3	1224203	1224937	-	DDB_G0278941	DDB_G0278941	NA
chr3	1225451	1229450	+	DDB_G0278809	cepG	localizes to the centrosome
chr3	1230143	1230578	+	DDB_G0278811	DDB_G0278811	NA
chr3	1230925	1231362	+	DDB_G0278813	DDB_G0278813	NA
chr3	1232003	1235140	-	DDB_G0278815	eIF5b	EIF5B ortholog%2C the eukaryotic initiation factor 5B%3B promotes the binding of tRNA to the ribosome
chr3	1235984	1237920	+	DDB_G0278817	DDB_G0278817	NA
chr3	1238183	1240456	+	DDB_G0278819	DDB_G0278819	ortholog of human CRNKL1 (crooked neck-like) involved in pre-mRNA splicing%3B contains 11 HAT (Half A TPR) repeats
chr3	1240717	1242542	+	DDB_G0278943	DDB_G0278943	tRNA-specific adenosine deaminase%2C deaminates adenosine-37 to inosine in tRNA-Ala%3B ortholog of %3Ci%3ES. cerevisiae%3C%2Fi%3E TAD1 and %3Ci%3EH. sapiens%3C%2Fi%3E adat1
chr3	1243062	1243559	+	DDB_G0278821	snrpF	NA
chr3	1243679	1244853	-	DDB_G0278823	DDB_G0278823	similar to human FDPS (farnesyl pyrophosphate synthetase) which is a key enzyme in isoprenoid biosynthesis%3B may have both dimethylallyltranstransferase and geranyltranstransferase activities
chr3	1245549	1247206	-	DDB_G0278735	fps	target for bisphosphonate drugs%3B catalyzes the reaction geranyl diphosphate %2B isopentenyl diphosphate %3C%3D%3E diphosphate %2B trans%2Ctrans-farnesyl diphosphate
chr3	1248051	1250768	+	DDB_G0278825	DDB_G0278825	NA
chr3	1251221	1252764	+	DDB_G0278945	DDB_G0278945	NA
chr3	1252983	1258539	-	DDB_G0278827	DDB_G0278827	NA
chr3	1258942	1260744	-	DDB_G0278829	DDB_G0278829	NA
chr3	1261226	1261756	+	DDB_G0278831	DDB_G0278831	NA
chr3	1262058	1262283	-	DDB_G0278833	DDB_G0278833	NA
chr3	1262788	1262895	-	DDB_G0278835	DDB_G0278835	NA
chr3	1263275	1263495	-	DDB_G0278837	DDB_G0278837	NA
chr3	1264354	1265291	+	DDB_G0278839	DDB_G0278839	NA
chr3	1265394	1267160	-	DDB_G0278841	DDB_G0278841	NA
chr3	1267448	1268800	-	DDB_G0278843	taf11	ortholog of H. sapiens and S. cerevisiae TAF11
chr3	1269374	1273426	-	DDB_G0278845	DDB_G0278845	member of the AGC kinase group%3B similar to kinase domains of NDR (nuclear Dbf2-related) family members
chr3	1274786	1275953	+	DDB_G0278847	psmA6	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr3	1276262	1278082	-	DDB_G0278849	etfdh	reduced electron-transferring flavoprotein %2B ubiquinone %3D electron-transferring flavoprotein %2B ubiquinol%3B accepts electrons from ETF and reduces ubiquinone%3B defects in human ETFDH cause glutaric aciduria type IIc (GAIIC)
chr3	1278474	1281570	-	DDB_G0278851	DDB_G0278851	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0278851 is similar to the rik1-associated factor raf1 of S. pombe. Raf1 (as well as rik1) participates in the Clr4 methyltransferase complex (see Horn et al%2C Genes and Development 19%2C 1705-1714) which methylates H3K9%2C important in silencing centromeric and telomeric repeats. It has recently been shown that these repeats are transcribed for a limited period during S-phase (Chen et al%2C Nature 451%2C 734-737 (2008)%2C that this transcription is essential for RNA-interference mediated heterochromatin assembly%2C and that the repeats are transcriptionally repressed outside of S-phase.%3Cbr%3E DDB_G0278851 and a second member of the Clr4 complex%2C the methyl transferase clr4%2FsuvA%2C are both overexpressed about threefold (p%3C2e-63) in a Dicty strain in which the retinoblastoma-like protein rblA has been disrupted. Most genes associated with S-phase or mitosis are overexpressed in this strain. The activity of the clr4 complex is thus likely to be S-phase associated. All these observations are consistent with a model in which the silencing methylation is directly coordinated with replication. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E
chr3	1282301	1282690	+	DDB_G0278853	DDB_G0278853	NA
chr3	1283399	1285516	+	DDB_G0278733	aip1	conserved protein%2C containing WD40 repeats%3B involved in actin-dependent processes such as endocytosis%2C  cytokinesis and motility%3B interacts genetically with nhe1 and suppresses nhe1- mutant phenotypes
chr3	1285622	1288868	-	DDB_G0278855	ptcH	NA
chr3	1289087	1289795	+	DDB_G0278857	DDB_G0278857	NA
chr3	1290736	1292456	+	DDB_G0278947	captB	catalyzes the reaction CDP-choline %2B 1%2C2-diacylglycerol %3D CMP %2B a phosphatidylcholine%3B putative ortholog of human CHPT1 
chr3	1292767	1295484	-	DDB_G0278859	DDB_G0278859	NA
chr3	1295784	1297232	-	DDB_G0278861	DDB_G0278861	NA
chr3	1298188	1299912	-	DDB_G0278863	fray1	kinase domain similar to OSR1 (oxidative stress responsive 1) kinases and other STE20-like kinases%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  Fray1 and Fray2  represent the FRAY-subfamily of Ste20-like kinases in D. discoideum  (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FSvkA%22%3Esevkin%3C%2Fa%3E for more information on Ste20 kinases).  In humans this family is represented by OSR (oxidative stress responsive kinase%2C a name that is a bit misleading as nobody showed a link between OSR and oxidative stress) and STLK3%2FSPAK. The fruit fly contains only the kinase Fray in this subfamily.  The Schleicher group is currently characterizing the phenotype of knockout mutants.  %3Cbr%2F%3E %3Ci%3EMeino Rohlfs%2C August 2006 %3C%2Fi%3E
chr3	1303121	1303711	+	DDB_G0278865	DDB_G0278865	NA
chr3	1304620	1310875	-	DDB_G0278867	gefBB	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr3	1313132	1316635	+	DDB_G0278869	DDB_G0278869	NA
chr3	1316821	1317345	-	DDB_G0278725	p17	similar to DDB_G0291255%3B contains a predicted signal peptide
chr3	1318190	1318536	-	DDB_G0278951	DDB_G0278951	NA
chr3	1320697	1321245	+	DDB_G0278871	DDB_G0278871	NA
chr3	1321299	1322102	-	DDB_G0278873	gnpda1	short version of the glucosamine-6-phosphate isomerase similar to fungi and metazoans%3B catalyzes the reaction D-glucosamine 6-phosphate %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E D-fructose 6-phosphate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr3	1323127	1326147	-	DDB_G0278875	dduD	contains a signal peptide%3B member of a Dictyostelium protein family that includes DG1041%3B downregulated in the uninfected %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr3	1327589	1332654	+	DDB_G0278879	gdt9	member of the TKL (tyrosine kinase-like) group and the GDT family
chr3	1333528	1334891	+	DDB_G0278881	DDB_G0278881	weakly similar to mannose-6-phosphate%2Finsulin-like growth factor 2 receptor
chr3	1335145	1336477	-	DDB_G0278953	DDB_G0278953	contains four CBS domains%3B similar to protein kinase 5%27AMP activated gamma subunit%3B expressed in prespore cells
chr3	1337376	1338350	+	DDB_G0278883	DDB_G0278883	NA
chr3	1338636	1340376	-	DDB_G0278885	sec61a	alpha subunit of the SEC61 complex (composed of %3Ca href%3D%22%2Fgene%2FDDB_G0278885%22%3ESec61a%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0278117%22%3ESec61b%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0287777%22%3ESec61g%3C%2Fa%3E) involved in protein targeting to the membrane
chr3	1341335	1341480	+	DDB_G0295543	sno18	expressed non-coding RNA%3B H%2FACA box snoRNAs are involved in rRNA processing
chr3	1341617	1341721	+	DDB_G0295545	sno4	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr3	1342274	1342981	-	DDB_G0278887	prafA	belongs to a conserved family of multi-pass transmembrane proteins%3B contains 3 predicted transmembrane domains
chr3	1343635	1344413	+	DDB_G0278889	mrpl27	protein component of the mitochondrial large ribosomal subunit
chr3	1344963	1346111	+	DDB_G0278891	DDB_G0278891	NA
chr3	1346298	1347566	-	DDB_G0278893	suox	catalyzes the reaction sulfite %2B O%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %3D sulfate %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3Cbr%3E ortholog of H. sapiens SUOX%2C of which defects cause isolated sulfite oxidase deficiency (ISOD) characterized by neurological abnormalities%3B requires molybdopterin cofactor
chr3	1348299	1352374	-	DDB_G0278895	cldA	NA
chr3	1358187	1358840	+	DDB_G0278897	DDB_G0278897	NA
chr3	1359880	1361085	+	DDB_G0278899	DDB_G0278899	NA
chr3	1361340	1366175	-	DDB_G0278901	DDB_G0278901	NA
chr3	1366879	1368192	+	DDB_G0278955	DDB_G0278955	NA
chr3	1368428	1369840	+	DDB_G0278903	DDB_G0278903	NA
chr3	1370259	1373274	+	DDB_G0278905	DDB_G0278905	NA
chr3	1373685	1374560	-	DDB_G0278907	mobA	similar to the Mob1 family of proteins%2C which are of unknown function but interact with Mps1 and NDR kinases%3B %3Ci%3EDictyostelium%3C%2Fi%3E MobA has been shown to bind  NdrA
chr3	1376167	1382125	+	DDB_G0278909	DDB_G0278909	member of the TKL (tyrosine kinase-like) group and the ARMK (armadillo repeat-containing kinase) family%3B contains an N-terminal LRR and a C-terminal armadillo%2Fbeta-catenin repeat%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr3	1382986	1384020	+	DDB_G0278911	DDB_G0278911	NA
chr3	1384248	1385606	+	DDB_G0278913	DDB_G0278913	NA
chr3	1385676	1386714	-	DDB_G0278957	DDB_G0278957	NA
chr3	1387306	1388202	-	DDB_G0278959	rpl9	protein component of the large (60S) ribosomal subunit%3B ribosomal protein L9 homolog
chr3	1389108	1391685	+	DDB_G0278729	repB	ortholog of H. sapiens xeroderma pigmentosum group B (XPB)%2C M. musculus ERCC3%2C and S. cerevisiae RAD25%3B upregulated in the presence of DNA damaging agents
chr3	1392137	1394101	+	DDB_G0278915	DDB_G0278915	NA
chr3	1394183	1397588	-	DDB_G0278741	adprt1A	ortholog of PARP1%3B catalyzes ADP-ribosylation%2C a posttranslational protein modification in which the ADP-ribose moiety of NAD is transferred onto specific amino acid side chains of cell surface%2C secreted%2C cytosolic or nuclear proteins%3B involved in double-strand break repair via nonhomologous end joining (NHEJ) and regulates single strand repair (SSBR)
chr3	1397821	1399400	-	DDB_G0278917	DDB_G0278917	NA
chr3	1399877	1404312	+	DDB_G0278919	DDB_G0278919	NA
chr3	1404420	1407320	-	DDB_G0278921	DDB_G0278921	contains a weak kinase domain and a putative TPR (tetratricopeptide repeat) domain
chr3	1407772	1410150	+	DDB_G0278923	DDB_G0278923	NA
chr3	1410371	1412462	+	DDB_G0278925	DDB_G0278925	NA
chr3	1412506	1413599	-	DDB_G0278961	DDB_G0278961	belongs to the PhyH family%3B homolog of human PHYHD1
chr3	1414868	1416355	+	DDB_G0278927	DDB_G0278927	NA
chr3	1417023	1419179	+	DDB_G0278929	usp39	similar to Arabidopsis thaliana ubiquitin carboxyl-terminal hydrolase family protein%3B ortholog of yeast SAD1%2C which plays a role in pre-mRNA splicing
chr3	1421183	1421650	+	DDB_G0278933	DDB_G0278933	NA
chr3	1421922	1424296	+	DDB_G0280845	DDB_G0280845	NA
chr3	1424429	1425509	-	DDB_G0280843	dgk	catalyzes the reaction ATP %2B deoxyguanosine %3D ADP %2B dGMP
chr3	1425826	1427385	-	DDB_G0280841	DDB_G0280841	NA
chr3	1427744	1428346	-	DDB_G0280839	DDB_G0280839	NA
chr3	1428903	1429852	-	DDB_G0280837	DDB_G0280837	NA
chr3	1430323	1430901	-	DDB_G0280835	DDB_G0280835	conserved protein in %3Ci%3EDictyostelium%3C%2Fi%3E%2C fungi%2C and bacteria
chr3	1430947	1431513	+	DDB_G0280833	DDB_G0280833_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	1431187	1431259	-	DDB_G0295165	tRNA-Lys-UUU-12	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr3	1432985	1434625	-	DDB_G0280831	DDB_G0280831	NA
chr3	1435464	1437785	+	DDB_G0280829	DDB_G0280829	NA
chr3	1437954	1439078	-	DDB_G0280819	aoxA	NA
chr3	1440057	1440625	-	DDB_G0280827	trappc4	ortholog of the trafficking protein particle complex subunit 4%2C part of the multisubunit TRAPP (transport protein particle) complex
chr3	1441074	1441741	+	DDB_G0280825	DDB_G0280825	similar to bacterial acetyltransferases%3B homolog of E. coli maa (maltose O-acetyltransferase)%3B similar to D. purpureum protein
chr3	1442353	1443385	+	DDB_G0280823	rps6	protein component of the small (40S) ribosomal subunit
chr3	1448552	1450485	-	DDB_G0278973	DDB_G0278973	NA
chr3	1450854	1455684	-	DDB_G0278975	DDB_G0278975	similar to comF
chr3	1457351	1459600	+	DDB_G0278977	DDB_G0278977	NA
chr3	1459749	1463597	-	DDB_G0278971	dimA	required for response to DIF-1
chr3	1466872	1468184	-	DDB_G0278979	DDB_G0278979	NA
chr3	1468580	1470456	+	DDB_G0279065	DDB_G0279065	NA
chr3	1470681	1472622	-	DDB_G0278981	DDB_G0278981	ortholog of the E3 ubiquitin-protein ligase TRIAD1 (Two RING fingers And Double RING finger Linked)%2C which is involved in the proteasomal degradation pathway%3B contains a ubiqutin associalte (UBA) domain and 2 RING-type zinc fingers sourrounding a cysteine-rich domain (C6HC)
chr3	1473189	1474126	-	DDB_G0278969	empC	NA
chr3	1474915	1475519	+	DDB_G0278983	imp3	ortholog of the conserved eukaryotic IMP3%3B component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) required for pre-18S rRNA processing%3B forms a heterotrimeric complex containing IMP4 and MPP10
chr3	1475884	1476812	-	DDB_G0278985	DDB_G0278985	NA
chr3	1477419	1478405	-	DDB_G0278987	DDB_G0278987	NA
chr3	1479334	1479798	+	DDB_G0278989	DDB_G0278989	NA
chr3	1480041	1485179	+	DDB_G0278965	DG2033	NA
chr3	1485914	1488923	-	DDB_G0278991	culE	similar to mammalian cullin 1%2C 2 and 5 (CUL1%2C CUL2%2C CUL5)%3B acts as scaffold for ubiquitin ligases (E3)%3B involved in ubiquitin-mediated protein degradation
chr3	1489337	1490448	+	DDB_G0278993	DDB_G0278993	NA
chr3	1494607	1498054	+	DDB_G0278995	DDB_G0278995	NA
chr3	1499624	1500572	+	DDB_G0278997	DDB_G0278997	conserved in bacteria and plants%3B there is an almost identical gene%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0278999%22%3E DDB_G0278999%3C%2Fa%3E downstream
chr3	1501033	1501994	+	DDB_G0278999	DDB_G0278999	conserved in bacteria and plants%3B there is an almost identical gene%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0278997%22%3E DDB_G0278997%3C%2Fa%3E upstream
chr3	1502267	1503059	+	DDB_G0279001	gmkA	catalyzes the reaction GMP %2B ATP %3C%3D%3E GDP %2B ADP in the %3Ci%3Ede novo%3C%2Fi%3E and salvage pathways of purine and pyrimidine nucleotides
chr3	1503809	1506692	+	DDB_G0279003	DDB_G0279003	NA
chr3	1507522	1509663	+	DDB_G0279005	DDB_G0279005	conserved hypothetical protein 
chr3	1510645	1512700	+	DDB_G0279009	gacP	NA
chr3	1513004	1513501	-	DDB_G0279011	DDB_G0279011	NA
chr3	1514463	1515327	+	DDB_G0279013	nola1	component of the H%2FACA small nucleolar ribonucleoprotein (H%2FACA snoRNP) complex required for pre-mRNA processing and pseudouridylation
chr3	1515905	1517172	+	DDB_G0279015	DDB_G0279015	conserved in bacteria and fungi
chr3	1517215	1518129	-	DDB_G0279017	DDB_G0279017	NA
chr3	1519155	1520138	+	DDB_G0279019	DDB_G0279019	NA
chr3	1520762	1522195	+	DDB_G0279067	DDB_G0279067	NA
chr3	1522629	1525694	+	DDB_G0279021	DDB_G0279021	NA
chr3	1526543	1527969	+	DDB_G0279023	DDB_G0279023	contains a predicted signal peptide and a putative transmembrane domain%3B contains a serine-rich region similar to bacterial SASA repeat
chr3	1528089	1528781	-	DDB_G0279069	DDB_G0279069	contains three predicted transmembrane domains
chr3	1529248	1531167	-	DDB_G0278967	eif2s3	NA
chr3	1533206	1534917	+	DDB_G0279031	cyp519H1_ps	putative pseudogene%3B related to the cytochrome P450 family
chr3	1534984	1537005	-	DDB_G0279033	DDB_G0279033	NA
chr3	1538571	1539599	+	DDB_G0279035	DDB_G0279035	NA
chr3	1539737	1540795	-	DDB_G0279037	coq3	similar to S. cevevisiae and R. norvegicus coq3%2C which catalyze two O-methylation steps in ubiquinone biosynthesis
chr3	1541078	1544303	+	DDB_G0279039	DDB_G0279039	NA
chr3	1545614	1547527	+	DDB_G0279041	DDB_G0279041	NA
chr3	1548383	1548649	+	DDB_G0295473	DDB_G0295473	glycine-rich%2C 52 amino acid protein
chr3	1548959	1549561	+	DDB_G0279043	DDB_G0279043	contains four putative ankyrin repeats
chr3	1550621	1550956	+	DDB_G0279073	DDB_G0279073	NA
chr3	1551325	1553266	+	DDB_G0279045	DDB_G0279045	NA
chr3	1553555	1554260	-	DDB_G0279047	DDB_G0279047	conserved protein%3B contains a signal peptide
chr3	1554715	1557635	+	DDB_G0279049	DDB_G0279049	conserved in dictyostelids%3B contains a predicted peroxisomal targeting signal
chr3	1559805	1563341	+	DDB_G0279051	DDB_G0279051	NA
chr3	1563766	1566821	+	DDB_G0279053	DDB_G0279053	catalyzes the reaction a 5%27-ribonucleotide %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E a ribonucleoside %2B phosphate
chr3	1568998	1572177	-	DDB_G0279055	DDB_G0279055_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	1572702	1573781	-	DDB_G0279077	DDB_G0279077_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	1574082	1574153	-	DDB_G0295163	tRNA-Cys-GCA-6	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr3	1574903	1575170	-	DDB_G0279057	DDB_G0279057	NA
chr3	1576793	1577940	+	DDB_G0279059	DDB_G0279059	NA
chr3	1578225	1578923	-	DDB_G0279061	rpl31	protein component of the large (60S) ribosomal subunit
chr3	1583286	1592966	+	DDB_G0279083	utp20	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA%3B contains a DRIM domain (Down-Regulated In Metastasis)
chr3	1598641	1600602	+	DDB_G0279085	cycA	 weakly similar to cyclin A%3B predicted to interact with the cyclin-dependent kinase CDK1%2F2 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272813%22%3E%3Ci%3Ecdk1%3C%2Fi%3E%3C%2Fa%3E)%3B contains a KEN box destruction motif predicted to be targeted for degradation by APC%2FCdh1%3Cbr%2F%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse the cycA gene encoding a cyclin with the cycA locus associated with resistance to cycloheximide (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Freference%2Freference.pl?refNo%3D3055%22%3EKatz %26 Sussman 1972%3C%2Fa%3E)
chr3	1601131	1601668	-	DDB_G0279087	med22	ortholog of the mediator of RNA polymerase II transcription subunit 22%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr3	1601965	1606352	-	DDB_G0279089	DDB_G0279089	NA
chr3	1608785	1613036	-	DDB_G0279091	DDB_G0279091	NA
chr3	1613622	1617399	+	DDB_G0279123	gxcCC	contains two actin binding domains%2C a putative calmodulin binding domain%2C and a Dbl homology (DH) domain specific for Rho guanine nucleotide exchange factors (GEF)
chr3	1618503	1620851	+	DDB_G0279093	DDB_G0279093	similar to kelch proteins that contain the BTB%2FPOZ domain and are actin binding proteins such as mayven and actinfilin%3B the BTB%2FPOZ domain contains the K%2B channel tertramerization domain
chr3	1621394	1622514	-	DDB_G0279081	abpB	 Ca2%2B-regulated 34 kDa actin-bundling protein
chr3	1624152	1624711	+	DDB_G0279095	ptsA	catalyzes the reaction 6-(L-erythro-1%2C2-dihydroxypropyl 3-triphosphate)-7%2C8-dihydropterin %3C%3D%3E 6-(1%2C2-dioxopropyl)-5%2C6%2C7%2C8-tetrahydropterin %2B triphosphate
chr3	1625351	1625880	+	DDB_G0279097	DDB_G0279097_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0275789%22%3EDDB_G0275789%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0280429%22%3EDDB_G0280429%3C%2Fa%3E
chr3	1626037	1632840	-	DDB_G0279099	DDB_G0279099	ortholog of DEPDC5%2C a conserved eukaryotic protein that may be involved in intracellular signaling
chr3	1633445	1633768	-	DDB_G0279101	DDB_G0279101	NA
chr3	1634323	1634622	-	DDB_G0279103	DDB_G0279103	NA
chr3	1635440	1638700	+	DDB_G0279105	DDB_G0279105	NA
chr3	1638888	1642604	-	DDB_G0279107	DDB_G0279107	NA
chr3	1642949	1645898	-	DDB_G0279109	eif3C	EIF3C ortholog%2C the eukaryotic initiation factor p110 subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr3	1646736	1648046	+	DDB_G0279111	DDB_G0279111	similar to mammalian TRIP13 (thyroid hormone receptor interactor 13) and S. cerevisiae PCH2 (Pachytene CHeckpoint)
chr3	1648404	1650743	-	DDB_G0279113	metS	catalyzes the reaction ATP %2B L-methionine %2B tRNAMet %3D AMP %2B diphosphate %2B L-methionyl-tRNAMet
chr3	1651481	1654895	+	DDB_G0279115	DDB_G0279115	NA
chr3	1657313	1657582	+	DDB_G0279117	DDB_G0279117	NA
chr3	1658002	1658258	-	DDB_G0279125	DDB_G0279125	NA
chr3	1658914	1659552	-	DDB_G0279119	DDB_G0279119	NA
chr3	1660011	1660469	+	DDB_G0279121	DDB_G0279121	NA
chr3	1660925	1663940	-	DDB_G0279127	DDB_G0279127_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr3	1669827	1670903	-	DDB_G0279153	DDB_G0279153_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	1671338	1671409	-	DDB_G0295161	tRNA-Cys-GCA-5	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr3	1671588	1672139	-	DDB_G0279131	DDB_G0279131	GFA enzymes catalyze the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione%3B all known members of this family contain 5 strongly conserved cysteine residues
chr3	1672697	1673557	+	DDB_G0279133	syn7B	similar to vertebrate syntaxin 7 involved in vesicle fusion
chr3	1673721	1674671	-	DDB_G0279135	DDB_G0279135	NA
chr3	1675769	1677652	-	DDB_G0279137	DDB_G0279137	catalyzes the reaction 5-methyltetrahydrofolate %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %3D 5%2C10-methylenetetrahydrofolate %2B NADPH %2B H%3Csup%3E%2B%3C%2Fsup%3E in various biosynthetic pathways
chr3	1678974	1680116	+	DDB_G0279139	DDB_G0279139	homolog of human ANKRD29%3B contains 8 ankyrin repeats
chr3	1680228	1683328	-	DDB_G0279141	ap1b1	highly similar to AP-1 complex subunit beta-1 (AP1B1) and AP-2 complex subunit beta-1 (AP2B1)%2C which play a role in clathrin-dependent protein sorting
chr3	1684165	1686506	+	DDB_G0279143	DDB_G0279143	NA
chr3	1686583	1688169	-	DDB_G0279145	DDB_G0279145	NA
chr3	1689106	1697393	+	DDB_G0279149	pip5k3	ortholog of mammlian PIP5K3 and S. cerevisiae FAB1%3B contains%2C in addition to the C-terminal PIP kinase domain%2C an N-terminal FYVE-type zinc finger domain and a central chaperonin Cpn60%2FTCP-1 domain
chr3	1697579	1698154	-	DDB_G0279151	cenB	centrin required for nuclear and centrosome stability%3B localizes to the nucleus in interphase but not during mitosis and is involved in the centrosome cycle
chr3	1698727	1700268	+	DDB_G0279155	DDB_G0279155	NA
chr3	1701022	1705842	+	DDB_G0279157	med16	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 16%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA 
chr3	1706026	1708044	+	DDB_G0279165	DDB_G0279165	NA
chr3	1708174	1711261	-	DDB_G0279159	aco1	catalyzes the reaction citrate %3C%3D%3E cis-aconitate %2B H%3Csub%3E2%3C%2Fsub%3EO%3B highly similar to iron responsive element binding protein%3B expressed in pstAB cells and in upper cup and stalk during culmination%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with aco%2C the oxidoreductase%2C or acoA%2C the acyl-CoA oxidase
chr3	1711904	1712440	+	DDB_G0279161	DDB_G0279161	NA
chr3	1712573	1713439	-	DDB_G0279163	DDB_G0279163	similar to hypothetical Dictyostelium proteins%3B enriched in gametes
chr3	1715076	1717952	+	DDB_G0279179	DDB_G0279179	NA
chr3	1718126	1722079	-	DDB_G0279167	topbp1	contains 7 BRCT domains%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Cut genes were originally identified in fission yeast as mutants that lead to cytokinesis in the absense of nuclear division%3B the name is derived from %22cell untimely torn%22[1][2]. The genes appear to be a heterogeneous group%2C most of which have functions required for nuclear division%2C rather than specifically in the dependence of cytokinesis on successful karyokinesis. Various cut proteins regulate chromosome condensation%2C assembly of the anaphase promoting complex%2C sister chromatid decatenation%2C spindle formation%2C and%2C somewhat discordantly%2C fatty acid synthesis[3]. Two Dicty genes have been named after the original S. pombe cut genes%2C cut5 (discussed here) and the fatty acid condensing enzyme cutA. Cut5 is widely conserved%3B in budding yeast it is known as DBP11 and in humans%2C topoisomerase binding protein 1 (TopBP1). Modern research has identified two roles%2C one in the initiation of DNA replication%2C where it interacts with the GINS complex and the other in DNA damage signalling%2C where it crosslinks the PCNA-like 9-1-1 complex with the DNA damage sensing kinase ATR%2C resulting in the phosphorylation and activation of the DNA damage effector kinase CHK1. %3Ci%3EHarry MacWilliams%2C September 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Ftopbp1%22%3E There is more information on the wiki page%3C%2Fa%3E
chr3	1722504	1725233	-	DDB_G0279169	vps39	ortholog of VPS39
chr3	1725633	1726064	+	DDB_G0306378	ostc	subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of human OSTC%3B contains three transmembrane domains
chr3	1726391	1727571	+	DDB_G0305545	DDB_G0305545	similar to D. purpureum protein
chr3	1727720	1728000	-	DDB_G0279175	hspc300	NA
chr3	1728295	1730367	+	DDB_G0279181	DDB_G0279181	NA
chr3	1731085	1734690	+	DDB_G0279183	kil2	possible magnesium pump involved in maintaining the phagosomal magnesium concentration optimal for proteolysis and efficient killing of bacteria
chr3	1734898	1736319	+	DDB_G0279177	DDB_G0279177	NA
chr3	1736871	1737809	+	DDB_G0279385	DDB_G0279385	NA
chr3	1738130	1738315	+	DDB_G0279197	DDB_G0279197	NA
chr3	1740048	1741532	+	DDB_G0279187	cprG	NA
chr3	1741814	1743031	-	DDB_G0279203	DDB_G0279203	NA
chr3	1744004	1746597	-	DDB_G0279195	adprt1B	highly similar to adprt1A%3B catalyzes ADP-ribosylation%2C a posttranslational protein modification in which the ADP-ribose moiety of NAD is transferred onto specific amino acid side chains of cell surface%2C secreted%2C cytosolic or nuclear proteins%3B involved in single strand break repair (SSBR)
chr3	1747299	1751183	-	DDB_G0279205	DDB_G0279205	similar to the conserved CAATT binding factor%2C which is essential for growth and necessary for 60S ribosomal subunit biogenesis
chr3	1751733	1752215	-	DDB_G0279387	rpl21	protein component of the large (60S) ribosomal subunit
chr3	1753571	1756469	-	DDB_G0295811	DDB_G0295811	NA
chr3	1757140	1758579	-	DDB_G0279185	cprF	enriched in prespore cells
chr3	1760514	1760960	+	DDB_G0279207	rps19	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S19 homolog
chr3	1761272	1761904	-	DDB_G0279209	DDB_G0279209	NA
chr3	1762684	1765261	-	DDB_G0279211	DDB_G0279211	catalyzes the reaction homocysteine %2B 5-methyltetrahydropteroyltri-L-glutamate %3C%3D%3E L-methionine %2B tetrahydropteroyltri-L-glutamate
chr3	1766422	1767386	-	DDB_G0279189	rpl11	protein component of the large (60S) ribosomal subunit
chr3	1768231	1771080	+	DDB_G0279213	DDB_G0279213	NA
chr3	1771918	1772731	-	DDB_G0279215	DDB_G0279215	NA
chr3	1773594	1773667	-	DDB_G0295159	tRNA-Arg-UCG-1	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr3	1773941	1775872	-	DDB_G0279217	DDB_G0279217_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr3	1779089	1780968	+	DDB_G0279219	DDB_G0279219	similar to D. purpureum protein%3B contains a cysteine-rich repeat motif found in Dictyostelium proteins (PF00526)
chr3	1781444	1781813	+	DDB_G0279221	DDB_G0279221	NA
chr3	1783778	1789076	+	DDB_G0279193	rpb1	component of the RNA polymerase II complex%3B ortholog of S. cerevisiae RPO21
chr3	1790126	1790778	+	DDB_G0279223	DDB_G0279223	contains a nucleic acid binding domain%2C the oligonucleotide%2Foligosaccharide binding motif (OB fold)
chr3	1791010	1793454	-	DDB_G0279225	DDB_G0279225	NA
chr3	1794406	1795711	+	DDB_G0279227	DDB_G0279227	NA
chr3	1796021	1796873	-	DDB_G0279229	DDB_G0279229	NA
chr3	1797887	1798899	+	DDB_G0279231	nse1	NA
chr3	1799975	1803118	-	DDB_G0279389	DDB_G0279389_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	1803409	1804743	-	DDB_G0279391	DDB_G0279391_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	1806047	1807381	-	DDB_G0279233	DDB_G0279233_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	1807996	1808069	+	DDB_G0295017	tRNA-Val-UAC-2	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr3	1809065	1811995	+	DDB_G0279237	DDB_G0279237	NA
chr3	1813505	1814489	+	DDB_G0279239	gtaY	contains a GATA Zinc finger%2C but missing a cysteine residue
chr3	1814829	1818189	-	DDB_G0279241	DDB_G0279241	NA
chr3	1820687	1822408	-	DDB_G0279243	DDB_G0279243	NA
chr3	1824604	1827101	+	DDB_G0279245	mpp10	ortholog of H. sapiens MPHOSPH10 and S. cerevisiae MPP10 protein%3B component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) required for pre-18S rRNA processing%3B forms a heterotrimeric complex containing IMP3%2C IMP4
chr3	1830468	1831196	+	DDB_G0279247	DDB_G0279247	similar to D. purpureum protein
chr3	1832140	1833102	+	DDB_G0279249	DDB_G0279249	NA
chr3	1833200	1837979	-	DDB_G0279251	DDB_G0279251	weakly similar to ints5%2C component of a multiprotein mediator of small nuclear RNA processing
chr3	1838283	1839914	-	DDB_G0279253	DDB_G0279253	NA
chr3	1840170	1845388	-	DDB_G0279255	DDB_G0279255	NA
chr3	1846173	1847156	-	DDB_G0279257	hbx8	NA
chr3	1848643	1851168	+	DDB_G0279259	DDB_G0279259	similar to bacterial GTP-binding protein engA
chr3	1851382	1852704	-	DDB_G0279393	DDB_G0279393	NA
chr3	1853231	1854643	-	DDB_G0279395	DDB_G0279395	NA
chr3	1855053	1856963	+	DDB_G0279261	DDB_G0279261	NA
chr3	1857138	1859575	-	DDB_G0279263	DDB_G0279263	NA
chr3	1859879	1860764	-	DDB_G0279265	DDB_G0279265	conserved protein of unknown function
chr3	1861211	1865976	-	DDB_G0279267	hdaD	catalyzes the removal of an acetyl group from lysine
chr3	1870767	1872072	+	DDB_G0279271	DDB_G0279271	belongs to the band 7 proteins%2C integral membrane proteins that ares thought to regulate cation conductance%3B stomatin is an erythrocyte membrane protein%3B contains an N-terminal transmembrane domain that might be a signal sequence
chr3	1872529	1872856	-	DDB_G0279273	DDB_G0279273	NA
chr3	1874332	1876203	+	DDB_G0279275	DDB_G0279275	NA
chr3	1876664	1877879	+	DDB_G0279277	DDB_G0279277	NA
chr3	1878087	1879323	+	DDB_G0279279	DDB_G0279279	NA
chr3	1879453	1882071	-	DDB_G0279281	mybV	contains one Myb DNA-binding domain
chr3	1882454	1884596	+	DDB_G0279285	DDB_G0279285	NA
chr3	1884785	1891355	-	DDB_G0279397	DDB_G0279397	NA
chr3	1892317	1893775	+	DDB_G0279287	DDB_G0279287	catalyzes the reaction L-cysteine %2B [enzyme]-cysteine %3C%3D%3E L-alanine %2B [enzyme]-S-sulfanylcysteine
chr3	1893937	1895062	-	DDB_G0279289	pmmA	catalyzes the reaction alpha-D-mannose 1-phosphate %3C%3D%3E D-mannose 6-phosphate
chr3	1895354	1896877	+	DDB_G0279291	DDB_G0279291	zinc metallopeptidase conserved in prokaryotes and eukaryotes
chr3	1897152	1897492	-	DDB_G0279293	DDB_G0279293	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr3	1897976	1898229	+	DDB_G0279399	DDB_G0279399_ps	putative pseudogene%3B hssA%2F2C%2F7E family gene
chr3	1898671	1899010	-	DDB_G0279295	DDB_G0279295	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr3	1899385	1899734	+	DDB_G0279297	DDB_G0279297	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr3	1899915	1900325	+	DDB_G0279299	DDB_G0279299	NA
chr3	1901303	1903976	+	DDB_G0279301	cax1	contains 13 transmembrane domains%3B transports Ca2%2B or other cations using the gradient of H%2B or Na%2B generated by energy-coupled primary transporters 
chr3	1904584	1906514	+	DDB_G0279303	slob2	similar to D. melanogaster Slob (Slowpoke binding protein) and mammalian Pxk (PX domain-containing kinase)%3B does not contain the consensus sequences required for kinase function%2C however%2C the Slob family encodes highly conserved non-canonical kinases that are believed to function
chr3	1907472	1908182	+	DDB_G0279305	rsmJ	NA
chr3	1908644	1910404	+	DDB_G0279307	vacC	very similar to %3Ci%3EDictyostelium%3C%2Fi%3E vacuolin A and B
chr3	1911215	1912993	+	DDB_G0279191	vacB	marker of the post-lysosomal vacuole%2C plays a role late in the endocytic pathway%2C may target the vacuole for exocytosis
chr3	1913378	1917128	-	DDB_G0279309	DDB_G0279309	similar to D. purpureum protein
chr3	1918418	1921048	-	DDB_G0279311	cdc5l	contains two Myb DNA-binding domains%3B ortholog of human CDC5L and yeast CEF1%3B may play a role in transcriptional activation and in mRNA splicing
chr3	1921668	1925073	+	DDB_G0279313	pigN	highly conserved protein involved in GPI anchor biosynthesis%3B ortholog of yeast MCD4
chr3	1925209	1927715	-	DDB_G0279315	gacN	NA
chr3	1928580	1930763	-	DDB_G0279317	DDB_G0279317	conserved protein%2C similar to the human C19orf29%2C a putative splice factor%2C identified in the spliceosome C complex
chr3	1931110	1932313	+	DDB_G0279319	DDB_G0279319	NA
chr3	1932547	1934192	+	DDB_G0279321	DDB_G0279321	NA
chr3	1934535	1936274	+	DDB_G0279323	DDB_G0279323	has similarity to H. sapiens Selenocysteine insertion sequence-binding protein 2 (SECISBP2) that binds to the 3%27-UTR of some mRNAs encoding selenoproteins
chr3	1936679	1941278	+	DDB_G0279325	DDB_G0279325	NA
chr3	1941566	1944999	-	DDB_G0279327	cnrP	ortholog of importin 9%2C a nuclear transport receptor that is thought to mediate docking of the importin%2Fsubstrate complex to the nuclear pore complex%3B identified as a suppressor of smlA null mutant cnr16
chr3	1945987	1950187	+	DDB_G0279329	DDB_G0279329	NA
chr3	1950418	1951240	-	DDB_G0279331	gtaR	has 20 amino acids between the two CX2C motifs
chr3	1951807	1953986	+	DDB_G0279335	DDB_G0279335	NA
chr3	1954714	1955838	+	DDB_G0279337	DDB_G0279337	NA
chr3	1955944	1957080	-	DDB_G0279339	DDB_G0279339	NA
chr3	1957657	1959219	+	DDB_G0279341	DDB_G0279341	NA
chr3	1959552	1961164	-	DDB_G0279343	aurK	putative protein serine%2Fthreonine kinase%2C Aur family%3B associates with the mitotic spindle and plays a key role in mitosis%3B the single  %3Ci%3EDictyostelium%3C%2Fi%3E aurora kinase has properties of both aurora A and B kinases in other organisms
chr3	1961529	1964457	-	DDB_G0279345	amfr	ortholog of the long isoform (isoform 2) of the human autocrine motility factor receptor%2C a RING finger-dependent ubiquitin protein ligase (E3) of the endoplasmic reticulum that is involved in tumor invasion and metastasis%3B contains four putative transmembrane domains and an additional signal sequence
chr3	1965450	1969859	+	DDB_G0279347	DDB_G0279347	NA
chr3	1970490	1971995	+	DDB_G0279403	cyp51	E-class P450%2C group IV%3B catalyzes the first step following cyclization in sterol biosynthesis%3B most prevalent cytochrome P450 across species
chr3	1972184	1974605	+	DDB_G0279349	alg9	CAZy family GT22%3B catalyzes N-linked mannosylation
chr3	1974768	1975241	-	DDB_G0279351	DDB_G0279351	NA
chr3	1975813	1977989	+	DDB_G0279405	DDB_G0279405	CAMKL family protein kinase%3B the protein kinase domain has similarity to those of calcium%2Fcalmodulin-dependent protein kinase kinases (CAMKK) that belong to a proposed calcium-triggered signaling cascade involved in a number of cellular processes
chr3	1978760	1980528	+	DDB_G0279353	DDB_G0279353	NA
chr3	1981638	1982980	+	DDB_G0279355	DDB_G0279355	NA
chr3	1983573	1984613	-	DDB_G0279357	DDB_G0279357	very similar to E.coli ybiK%2C a putative L-asparaginase of the asparagine 2 family%2C with the likely catalytic activity L-asparagine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E L-aspartate %2B NH%3Csub%3E3%3C%2Fsub%3E%3B contains InterPro %27Peptidase T2%2C asparaginase 2%27 domain which includes L-asparaginases and glycosylasparaginases
chr3	1984933	1985585	+	DDB_G0279359	ap1s1	similar to clathrin coat assembly protein AP19
chr3	1986517	1987341	+	DDB_G0279361	DDB_G0279361	NA
chr3	1987447	1988114	-	DDB_G0279363	DDB_G0279363	NA
chr3	1988545	1992433	-	DDB_G0279365	DDB_G0279365	NA
chr3	1993529	1995220	-	DDB_G0279367	DDB_G0279367	NA
chr3	1995959	1998148	-	DDB_G0279369	DDB_G0279369	NA
chr3	2000722	2004171	-	DDB_G0279371	utp14	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr3	2004876	2006425	+	DDB_G0279373	snf5	SNF5 homolog%2C putative chromatin remodeling complex subunit
chr3	2006606	2007698	-	DDB_G0279375	DDB_G0279375	related to the Ovarian Tumour (OTU) gene of Drosophila%3B function is unknown but conserved cysteine and histidine%2C and possibly the aspartate%2C residues suggests that those not yet recognized as peptidases could possess cysteine protease activity
chr3	2008109	2009852	+	DDB_G0279377	gtf2f1	NA
chr3	2010240	2013683	-	DDB_G0302530	DDB_G0302530	NA
chr3	2014573	2016449	+	DDB_G0279381	DDB_G0279381	NA
chr3	2017692	2018908	+	DDB_G0279383	DDB_G0279383	NA
chr3	2020767	2022239	+	DDB_G0279419	nfyB	putative ortholog of the B subunit of the heterotrimeric transcription factor NFY%2C composed of NfyA%2C NfyB%2C and NfyC
chr3	2022765	2023750	-	DDB_G0279421	DDB_G0279421	NA
chr3	2025317	2030760	+	DDB_G0279425	DDB_G0279425	NA
chr3	2032053	2034159	-	DDB_G0279427	DDB_G0279427	highly similar to sestrin1%2C p53-regulated protein PA26 in human%2C a potential regulator of cellular growth
chr3	2037686	2039852	-	DDB_G0279429	DDB_G0279429	NA
chr3	2040372	2042087	-	DDB_G0279431	DDB_G0279431	NA
chr3	2043258	2045009	-	DDB_G0279433	metap1	catalyzes the release of N-terminal amino acids%2C preferentially methionine%2C from peptides and arylamides
chr3	2045716	2047346	-	DDB_G0279435	DDB_G0279435	NA
chr3	2047840	2049064	-	DDB_G0279437	DDB_G0279437	contains an N-terminal DOMON domain as it occurs in dopamine beta-monooxygenases%3B the %3Ci%3EDictyostelium%3C%2Fi%3E protein is followed by a cytochrome b561 domain%2C which contains 5 putative transmembrane regions%3B in addition%2C the protein contains a putative signal peptide
chr3	2050082	2052571	-	DDB_G0279439	bzpC	NA
chr3	2053494	2057010	-	DDB_G0279441	ipo13B	ortholog of importin 13%2C also known as Ran-binding protein 13%2C a nuclear transport receptor serves as receptor for nuclear localization signals (NLS) in cargo substrates and mediates docking of the importin%2Fsubstrate complex to the nuclear pore complex
chr3	2058202	2059086	+	DDB_G0279443	aqpB	belongs to the MIP (major intrinsic protein) family%3B contains 6 putative transmembrane domains
chr3	2059799	2060751	+	DDB_G0279445	ctns	ortholog of cytonisin (CTNS)%3B in human mutations in the gene causes cystinosis%2C a disease resulting from defective lysosomal transport of cystine%3B the classical nephropathic form is characterized by renal failure at age 10%3B contains 7 transmembrane domains
chr3	2061353	2061838	-	DDB_G0279447	hspJ	NA
chr3	2062975	2066277	+	DDB_G0279449	DDB_G0279449	NA
chr3	2066556	2067929	-	DDB_G0279451	drg2	ortholog of human DRG2%2C which may be involved in cell proliferation%2C differentiation and death%3B highly conserved in eukaryotes%3B belongs to the GTP1%2FOBG family
chr3	2068536	2071742	-	DDB_G0279453	DDB_G0279453	NA
chr3	2074339	2075435	+	DDB_G0279455	DDB_G0279455	NA
chr3	2076549	2076763	+	DDB_G0279457	DDB_G0279457_ps	putative pseudogene%3B small fragment%2C similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0288731%22%3EDDB_G0288731%3C%2Fa%3E
chr3	2077799	2081114	-	DDB_G0279459	DDB_G0279459	%3Cb%3ECommunity Annotation%3C%2Fb%3E DDB G0279459 contains a forkhead-associated domain which is similar to the corresponding domain in the KI-67 antigen%2C a very widely used clinical proliferation marker%2C and is the only hit when the KI-67 sequence is blasted against Dicty proteins. Direct comparison of the Dd sequence with KI-67 by Blast2Sequences identifies two regions of homology and gives an expected value of 4e-08%2C suggesting that the similarity may be real. The KI-67 antigen in humans is nuclear and present throughout the cell cycle in proliferating cells%2C but undetectable in cells in G0. Recent work suggests that the protein is involved in ribosomal RNA synthesis ((Bullwinkel et al%2C J Cell Physiology 206%2C 624-635 (2005)%3B Rahmanzadeh et al%2C Cell and Molecular Biology 40%2C 422-430 (2007). A role in chromatin compaction has also been ascribed to KI-67 (Kametaka et al%2C Genes Cells 7%2C 1231-42 (2002) but this appears to involve the C-terminus. The Dicty protein is significantly shorter than the human protein and the homologies appear confined to the N-terminus.%3Cbr%3E DDB G0279459 is 13-fold overexpressed in a Dicty strain missing the retinoblastoma-like gene rblA (the p-value for the null hypothesis is too small to calculate). Most of the genes overexpressed in this strain are associated with cell cycle progression. DDB G0279459 also shows a developmental trajectory (high between T8 and T16%2C low otherwise) typical for cell-cycle associated genes%2C see DictyExpress). DDB_G0279459 thus appears to be associated with proliferation in Dicty%2C as KI-67 is in metazoans. %3Ci%3EHarry MacWilliams%2C March 2010%3C%2Fi%3E
chr3	2082919	2086134	+	DDB_G0279461	DDB_G0279461	protein phosphatase 2C is a serine%2Fthreonine specific protein phosphatase with broad substrate specificity and dependent on divalent cations (mainly manganese and magnesium) for its activity
chr3	2087531	2089153	+	DDB_G0279463	DDB_G0279463	NA
chr3	2089639	2090237	+	DDB_G0279589	DDB_G0279589	NA
chr3	2090462	2092082	-	DDB_G0279465	tgds	similar to dTDP-D-glucose 4%2C6-dehydratase%2C which catalyzes the reaction dTDP-glucose %3C%3D%3E dTDP-4-dehydro-6-deoxy-D-glucose %2B H%3Csub%3E2%3C%2Fsub%3EO
chr3	2094570	2101013	+	DDB_G0279417	roco6	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains LRR%2C Roc%2C COR%2C WD40%2C PH%2C and protein kinase domains
chr3	2101459	2101584	-	DDB_G0279467	DDB_G0279467	contains one putative transmembrane domain
chr3	2102943	2103065	-	DDB_G0279469	DDB_G0279469_RTE	ORF2 protein short fragment of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	2103501	2103571	-	DDB_G0295157	tRNA-Gly-GCC-10	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	2104523	2105867	+	DDB_G0279411	ctsD	NA
chr3	2106661	2107082	+	DDB_G0279471	DDB_G0279471	NA
chr3	2107184	2108727	-	DDB_G0279473	DDB_G0279473	NA
chr3	2109355	2111562	-	DDB_G0279591	glnA3	catalyzes the reaction ATP %2B L-glutamate %2B ammonia %3D ADP %2B phosphate %2B L-glutamine
chr3	2113626	2114348	-	DDB_G0279475	gna1	gna %3D %3Cb%3EG%3C%2Fb%3Elucosami%3Cb%3EN%3C%2Fb%3Ee-6-phosphate %3Cb%3EA%3C%2Fb%3Ecetyltransferase
chr3	2114897	2119637	+	DDB_G0279477	DDB_G0279477	NA
chr3	2120059	2120364	+	DDB_G0279479	DDB_G0279479	similar to S. cerevisiae YOS1 which is required for protein transport between endoplasmic reticulum and Golgi apparatus.
chr3	2120888	2121862	+	DDB_G0279481	ccdc94	conserved hypothetical protein containing domain of unknown function DUF572%3B ortholog of human CCDC94 and yeast YJU2%2FCWF16 believed to be involved in mRNA splicing
chr3	2122585	2126750	+	DDB_G0279483	pldB	catalyzes the reaction a phosphatidylcholine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E choline %2B a phosphatidate%3B plays a role in quorum sensing during aggregation
chr3	2127093	2131698	-	DDB_G0279485	DDB_G0279485	NA
chr3	2132450	2140696	-	DDB_G0279487	DDB_G0279487	ortholog of yeast GCN1 and human GCN1L1
chr3	2141942	2144526	+	DDB_G0279593	DDB_G0279593	putative ortholog of human KIAA0082%3B RrmJ (FtsJ) is a well conserved heat shock protein%2C in prokaryotes responsible for methylating the 23 S rRNA at position U2552 in the aminoacyl (A)1-site of the ribosome
chr3	2144687	2147315	-	DDB_G0279489	DDB_G0279489	NA
chr3	2147617	2149527	-	DDB_G0279491	DDB_G0279491	NA
chr3	2150258	2152592	+	DDB_G0279493	DDB_G0279493	NA
chr3	2153440	2153814	+	DDB_G0279495	DDB_G0279495	NA
chr3	2155142	2156218	-	DDB_G0279595	DDB_G0279595_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	2156654	2156725	-	DDB_G0295155	tRNA-Glu-UUC-13	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr3	2157078	2158745	-	DDB_G0279497	DDB_G0279497	NA
chr3	2159836	2160539	-	DDB_G0279499	DDB_G0279499	NA
chr3	2160865	2165924	+	DDB_G0279501	DDB_G0279501	NA
chr3	2166622	2170410	+	DDB_G0279597	DDB_G0279597	similar to D. purpureum protein
chr3	2170637	2171942	+	DDB_G0279503	DDB_G0279503	NA
chr3	2172140	2172712	-	DDB_G0279505	DDB_G0279505	NA
chr3	2174875	2176510	+	DDB_G0279507	plrg1	conserved protein that seems necessary for spliceosome assembly and for pre-mRNA splicing
chr3	2176877	2180563	+	DDB_G0279509	DDB_G0279509	NA
chr3	2181977	2185666	+	DDB_G0279511	DDB_G0279511	NA
chr3	2186381	2188234	+	DDB_G0279513	DDB_G0279513	NA
chr3	2188620	2192094	-	DDB_G0279515	pigQ	putative glycosyltransferase involved in GPI biosynthesis%3B subunit of the transferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-N-acetylglucosamine to phosphatidylinositol (PI) 
chr3	2192375	2194027	+	DDB_G0279517	DDB_G0279517	NA
chr3	2194197	2194910	-	DDB_G0279519	mrpl22	protein component of the mitochondrial large ribosomal subunit
chr3	2195759	2196668	+	DDB_G0279415	limE	NA
chr3	2196884	2197596	-	DDB_G0279521	DDB_G0279521	NA
chr3	2198274	2200498	-	DDB_G0279523	DDB_G0279523	NA
chr3	2201116	2201861	+	DDB_G0279525	DDB_G0279525	NA
chr3	2202606	2206383	+	DDB_G0279527	DDB_G0279527	NA
chr3	2206682	2208577	-	DDB_G0279529	bzpF	NA
chr3	2212555	2214319	+	DDB_G0279599	crlG	similar to the G-protein coupled receptors%3B contains 7 putative transmembrane domains and a putative signal peptide
chr3	2214566	2216943	+	DDB_G0279601	utp6	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr3	2217133	2218055	-	DDB_G0279531	DDB_G0279531	NA
chr3	2218849	2220534	-	DDB_G0279533	DDB_G0279533	NA
chr3	2220986	2221876	+	DDB_G0279535	DDB_G0279535	putative ortholog to H. sapiens U4%2FU6.U5 tri-snRNP-associated protein 3%2C also known as nucleic acid-binding protein RY-1
chr3	2222668	2223895	-	DDB_G0279413	pkaR	NA
chr3	2224744	2228335	-	DDB_G0279537	ap3d1	NA
chr3	2228944	2231145	+	DDB_G0279539	DDB_G0279539	NA
chr3	2232590	2235046	+	DDB_G0294635	DDB_G0294635	contains a signal peptide and a transmembrane domain
chr3	2235559	2236280	+	DDB_G0279541	DDB_G0279541	NA
chr3	2236357	2236723	-	DDB_G0279543	DDB_G0279543	NA
chr3	2237325	2238381	-	DDB_G0279545	DDB_G0279545	similar to bacterial short-chain dehydrogenase%2Freductase family proteins
chr3	2239673	2240817	+	DDB_G0279547	DDB_G0279547	NA
chr3	2241015	2242522	-	DDB_G0279549	eif3G	EIF3G ortholog%2C the eukaryotic initiation factor delta subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr3	2242950	2243738	-	DDB_G0279551	DDB_G0279551	NA
chr3	2244074	2245039	-	DDB_G0279407	calA	calcium-dependent regulatory protein involved in cytokinesis%3B regulated by cytosolic Ca2%2B fluxes allowing differential binding to target CaM binding proteins (CaMBPs)%3B binds several proteins%2C among them nuclear NumA and Cdk5
chr3	2245750	2247159	-	DDB_G0279553	nuf2	ortholog of NUF2%2C a component of the evolutionarily conserved kinetochore-associated Ndc80 complex (in S. pombe%2C composed of: Ndc80-Nuf2-Spc24-Spc25)
chr3	2248374	2250101	+	DDB_G0279555	tmem184C	putative ortholog of the human transmembrane protein 184C%3B contains 6 predicted transmembrane domains
chr3	2250584	2253245	-	DDB_G0279557	DDB_G0279557	contains 8 PUF domains%3B D. melanogaster pumilio binds through a PUF domain to the 3%27 UTR of target mRNAs
chr3	2257247	2260974	-	DDB_G0279559	pcf11	similar to S. cerevisiae and human PCF11%2C which in yeast is involved in pre-mRNA 3%27-end processing
chr3	2261454	2263171	-	DDB_G0279561	DDB_G0279561	protein that contains a conserved domain shared by acyl-CoA synthetases%2C long chain fatty acid Co-A ligase and various other closely-related synthetases
chr3	2264498	2265670	+	DDB_G0279563	DDB_G0279563	NA
chr3	2265879	2269163	-	DDB_G0279565	DDB_G0279565	NA
chr3	2271017	2271847	+	DDB_G0279567	DDB_G0279567	NA
chr3	2272081	2277554	-	DDB_G0279569	gflD	contains RhoGAP and RasGEF domains and a GRAM domain%2C which is found in membrane-associated proteins
chr3	2278573	2280186	-	DDB_G0279571	DDB_G0279571	contains repeats found in several Chlamydia polymorphic membrane proteins
chr3	2280534	2286201	-	DDB_G0279573	DDB_G0279573	NA
chr3	2286922	2292826	-	DDB_G0279575	DDB_G0279575	contains a predicted signal peptide and 7 putative transmembrane domains
chr3	2293478	2299214	-	DDB_G0279577	DDB_G0279577	NA
chr3	2300516	2300577	-	DDB_G0295547	r36	small non-coding RNA (59-60 nt) containing 5%27 and 3%27 ends predicted to form a stem structure%3B localizes to the cytoplasm
chr3	2301120	2301583	-	DDB_G0279581	DDB_G0279581	NA
chr3	2302296	2305061	+	DDB_G0279583	DDB_G0279583	NA
chr3	2305662	2306846	+	DDB_G0279585	DDB_G0279585	NA
chr3	2307458	2308309	+	DDB_G0279587	DDB_G0279587	NA
chr3	2308619	2312032	-	DDB_G0279409	cbfA	nuclear DNA-binding protein%3B binds to C-module of retrotransposon DRE%3B general transcriptional regulator
chr3	2313265	2314626	-	DDB_G0279609	DDB_G0279609	similar to Physarum polycephalum actin-fragmin kinase%3B enriched in gametes
chr3	2316340	2317367	-	DDB_G0279611	DDB_G0279611	NA
chr3	2317988	2319847	+	DDB_G0279613	DDB_G0279613	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr3	2320738	2321070	+	DDB_G0279615	DDB_G0279615	NA
chr3	2321489	2322121	-	DDB_G0279617	DDB_G0279617	NA
chr3	2325510	2326037	-	DDB_G0279619	DDB_G0279619	NA
chr3	2327562	2328077	-	DDB_G0279621	DDB_G0279621	NA
chr3	2329430	2329918	-	DDB_G0279623	DDB_G0279623	NA
chr3	2330677	2330748	+	DDB_G0295019	tRNA-Cys-GCA-2	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2331609	2332754	+	DDB_G0279721	ubqH	NA
chr3	2333074	2333220	-	DDB_G0279625	DDB_G0279625	NA
chr3	2333694	2334224	-	DDB_G0279627	DDB_G0279627	NA
chr3	2335074	2337125	-	DDB_G0279629	lkb1	CAMK group%2C CAMKL family  kinase%3B protein kinase involved in regulating both development and the stress response
chr3	2338838	2342556	-	DDB_G0279631	cyp513G1_ps	putative pseudogene%3B related to the cytochrome P450 family
chr3	2343459	2344670	-	DDB_G0279633	psmD7	NA
chr3	2345293	2346834	+	DDB_G0279635	DDB_G0279635	NA
chr3	2347354	2348655	+	DDB_G0279637	DDB_G0279637	NA
chr3	2350407	2353794	-	DDB_G0279639	DDB_G0279639	NA
chr3	2354365	2355712	+	DDB_G0279641	sae1	conserved protein%2C forms a heterodimer with sae2 (uba2)%3B acts as a E1 ligase for sumo
chr3	2356584	2358923	+	DDB_G0279643	DDB_G0279643	NA
chr3	2359062	2360328	-	DDB_G0279645	DDB_G0279645	NA
chr3	2361407	2362691	+	DDB_G0279647	DDB_G0279647	NA
chr3	2363863	2368238	+	DDB_G0279649	acapA	plays a role in cytokinesis%2C lysosome maturation%2C cell migration and actin cytoskeleton dynamics%3B hydrolyzes GTP bound to ArfA in vitro
chr3	2369571	2369825	-	DDB_G0279651	DDB_G0279651	NA
chr3	2370154	2371319	-	DDB_G0279605	racB	NA
chr3	2372697	2374976	-	DDB_G0279653	DDB_G0279653	NA
chr3	2376263	2377906	-	DDB_G0279655	DDB_G0279655	similar to %3Ci%3EDictyostelium%3C%2Fi%3E and %3Ci%3EH. sapiens%3C%2Fi%3E ppp2r4 (PTPA)%2C the phosphatase 2A regulatory subunit B%27
chr3	2378488	2383621	-	DDB_G0279657	elmoE	NA
chr3	2384965	2387825	+	DDB_G0279723	med17	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 17%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr3	2388583	2393474	+	DDB_G0279607	forA	NA
chr3	2394194	2396335	-	DDB_G0279727	DDB_G0279727	NA
chr3	2397433	2400394	+	DDB_G0279659	snd1	similar to 100 kDa transcription coactivator
chr3	2401539	2402075	+	DDB_G0279661	DDB_G0279661	shares a short region of similarity with the SOX transcription factors%3B contains a single HMG1%2F2 box
chr3	2402323	2403099	-	DDB_G0279663	DDB_G0279663	NA
chr3	2405211	2409344	+	DDB_G0279665	DDB_G0279665	NA
chr3	2410613	2411077	+	DDB_G0279667	H2AX	component of the H2A-H2B-H3-H4 histone octamer%3B dimerizes with histone H2B
chr3	2411509	2414036	+	DDB_G0279669	fncE	putative ortholog of Fanconi anaemia complementation group E protein%2C involved DNA cross-link repair%3B  null mutant is sensitive to DNA damaging agents%3Cbr%2F%3E%3Cbr%2F%3E mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A%2C B%2C C%2C E%2C F%2C G%2C L and M%3B  the FA complex interacts with ube2t%2C a E2 ubiquitin-conjugating enzyme%2C to monoubiquitinate  FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the  FANCJ helicase as well as FANCN and FANCD1%3B in human%2C mutations in this gene cause Fanconi anaemia%2C an autosomal recessive disorder affecting all bone marrow elements%3B Dictyostelium has orthologs for %3Ca href%3D%22%2Fgene%2FDDB_G0268216%22%3EFANCD2%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0279669%22%3EFANCE%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0292744%22%3EFANCL%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0293476%22%3EFANCI%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0286621%22%3EFANCJ%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274841%22%3EFANCM%3C%2Fa%3E and   %3Ca href%3D%22%2Fgene%2FDDB_G0291199%22%3EUbe2t%3C%2Fa%3E.
chr3	2414162	2415887	-	DDB_G0279671	DDB_G0279671	NA
chr3	2416668	2418608	-	DDB_G0279673	DDB_G0279673	NA
chr3	2424448	2426258	+	DDB_G0295731	DDB_G0295731	NA
chr3	2426331	2428066	-	DDB_G0279675	DDB_G0279675	belongs to the carbon-nitrogen hydrolase family%3B similar to human VNN1 (pantetheine hydrolase)%3B contains a predicted signal anchor sequence
chr3	2428511	2429375	-	DDB_G0279677	denr	conserved protein%3B contains a translation initiation factor SUI1 domain
chr3	2429651	2430584	-	DDB_G0279679	DDB_G0279679	NA
chr3	2431375	2432326	+	DDB_G0279731	DDB_G0279731	NA
chr3	2433796	2439149	+	DDB_G0279733	gxcDD	multifunctional protein containing a Rac exchange factor domain%2C an Arf GTPase activating domain%2C a CH domain%2C two IQ motifs and three PH domains
chr3	2439525	2440220	+	DDB_G0294567	DDB_G0294567	NA
chr3	2440539	2441421	+	DDB_G0279681	DDB_G0279681	contains four EF-hands
chr3	2441695	2442513	+	DDB_G0279683	DDB_G0279683	NA
chr3	2442573	2443616	-	DDB_G0279685	DDB_G0279685	NA
chr3	2443914	2443986	+	DDB_G0295021	tRNA-Asn-GUU-11	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2445627	2445896	+	DDB_G0279687	DDB_G0279687	contains one proline-rich domain
chr3	2446020	2449616	-	DDB_G0279689	eftud1	highly conserved protein that is similar to elongation factor Tu
chr3	2450297	2450368	+	DDB_G0295023	tRNA-Cys-GCA-3	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2450743	2452695	+	DDB_G0279691	DDB_G0279691_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	2453262	2456643	-	DDB_G0279693	DDB_G0279693	contains 1 importin N-terminal domain%3B homolog of human IPO11 (importin-11) and S. cerevisiae KAP120 (importin beta-like protein)%2C both of which function in nuclear protein import as a nuclear transport receptor
chr3	2457402	2457891	+	DDB_G0279695	DDB_G0279695	similar D. melanogaster ORF CG8021%2C and the RRM domain is similar to that of human RBM3
chr3	2458047	2458484	-	DDB_G0279697	DDB_G0279697	NA
chr3	2459375	2461348	+	DDB_G0279699	DDB_G0279699	contains a MOZ%2FSAS-like domain (Monocytic leukemia Zinc finger and Something About Silencing) predicted to have histone acetyltransferase activity
chr3	2461693	2464150	+	DDB_G0294609	polD3	similarity to POLD3 and cdc27 is weak%2C but contains the PCNA-binding motif
chr3	2464297	2465421	-	DDB_G0279701	DDB_G0279701	NA
chr3	2466144	2468855	+	DDB_G0279703	prpf4B	protein serine%2Fthreonine kinase%2C DYRK family%3B member of the CMGC kinase group%3B similar to mammalian pre-mRNA processing factor PRP4 kinase and DYRK kinases
chr3	2469013	2469762	-	DDB_G0279705	aplE	NA
chr3	2470281	2470934	-	DDB_G0279707	iliP	contains a predicted signal peptide%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection%3B there are two similar genes in D. discoideum
chr3	2471727	2472482	-	DDB_G0279709	DDB_G0279709	member of a Dictyostelium protein family that includes %3Ca href%3D%22%2Fgene%2FDDB_G0287587%22%3E%3Ci%3EsmlA%3C%2Fi%3E%3C%2Fa%3E%2C which is expressed in vegetative and early developing cells and is involved in aggregate formation
chr3	2473335	2473844	+	DDB_G0279711	cmr	similar to comitin%2C a lectin and actin binding protein linking the actin cytoskeleton to the Golgi apparatus
chr3	2474053	2474909	-	DDB_G0279713	aplK	expressed in pstAO cells and in upper and lower cups during culmination
chr3	2475392	2476840	-	DDB_G0279715	mtyrS	catalyzes the reaction ATP %2B L-Tyrosine %2B tRNATyr %3D AMP %2B diphosphate %2B L-tyrosyl-tRNATyr%3B similar to bacterial tyrosine-tRNA ligases
chr3	2477453	2479054	-	DDB_G0279717	DDB_G0279717	contains a putative signal peptide
chr3	2480611	2483596	-	DDB_G0279719	DDB_G0279719	putative protein serine%2Fthreonine kinase%3B similar to vertebrate Nek kinases which are involved in regulation of mitosis
chr3	2486411	2488090	-	DDB_G0279739	trmt5	ortholog of the mammalian TRMT5 and the %3Ci%3ES. cerevisiae%3C%2Fi%3E TRM5  tRNAmethyltransferase that methylates guanosine-37 in various tRNAs
chr3	2491660	2494914	+	DDB_G0279741	DDB_G0279741	NA
chr3	2495088	2496449	-	DDB_G0279743	DDB_G0279743	NA
chr3	2496825	2498177	-	DDB_G0279745	DDB_G0279745	NA
chr3	2498789	2499747	+	DDB_G0279747	DDB_G0279747	NA
chr3	2499904	2500343	-	DDB_G0279749	DDB_G0279749	NA
chr3	2501638	2503774	+	DDB_G0279751	DDB_G0279751	unknown protein%3B the C-terminal part has been deleted in axenic strains together with the large partial deletion of the downstream %3Ci%3EaxeB%3C%2Fi%3E gene
chr3	2504484	2505374	+	DDB_G0350652	axeB	this locus has been identified by %3Ca href%3D%22%2Fpublication%2Fpubmed%2F25815683%22%3EBloomfield 2015 %3Ci%3Eet al.%3C%2Fi%3E%3C%2Fa%3E as the large deletion that allows axenic strains to grow by fluid uptake%3B the gene fragment represented here encodes the C-terminal 296 amino acids of the %3Ci%3EDictyostelium%3C%2Fi%3E RasGAP neurofibromin 1%2C the complete protein is  2605 amino acids long (%3Ca href%3D%22http:%2F%2Fwww.uniprot.org%2Funiprot%2FW6K4Y2%22 target%3D%22new%22%3EW6K4Y2%3C%2Fa%3E) in strain DdB%3B the deletion of %3Ci%3EaxeB%3C%2Fi%3E shows its function in macropinocytosis and phagocytosis
chr3	2506085	2509939	+	DDB_G0279753	DDB_G0279753	NA
chr3	2510417	2512172	+	DDB_G0279755	DDB_G0279755	contains a nucleic acid binding domain%2C the oligonucleotide%2Foligosaccharide binding motif (OB fold)%3B similar to conserved hypothetical fungal proteins
chr3	2512313	2516167	-	DDB_G0279737	top2mt	controls the topological state of DNA by transient double-strand breakage and subsequent rejoining of DNA strands%3B Top2mt has been shown to be localized to the  mitochondria
chr3	2516476	2517190	+	DDB_G0279787	DDB_G0279787	NA
chr3	2517567	2518259	+	DDB_G0279789	DDB_G0279789	NA
chr3	2518903	2520445	+	DDB_G0279791	plnA	similar to the perilipin family involved in the development and maintenance of adipose tissue
chr3	2520955	2521932	+	DDB_G0279757	DDB_G0279757	NA
chr3	2522049	2524167	-	DDB_G0279759	DDB_G0279759	NA
chr3	2524840	2526402	+	DDB_G0279793	lap	lap %3D %3Cb%3EL%3C%2Fb%3Eeucine %3Cb%3EA%3C%2Fb%3Emino %3Cb%3EP%3C%2Fb%3Eeptidase
chr3	2526528	2527832	-	DDB_G0279761	DDB_G0279761	atypical protein kinase%3B similar to human G11 serine threonine protein kinase (STK19%2C part of the major histocompatibility complex)
chr3	2528127	2529775	-	DDB_G0279763	cyp513D1	NA
chr3	2530587	2533361	-	DDB_G0279765	DDB_G0279765	NA
chr3	2533940	2535496	+	DDB_G0279767	DDB_G0279767	NA
chr3	2535702	2536946	-	DDB_G0279769	psmG1	conserved chaperone protein%2C which promotes assembly of the 20S proteasome%3B may form a dimer with psmG2 and act in concert with psmG3%2FpsmG4
chr3	2537528	2538343	-	DDB_G0279771	DDB_G0279771_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr3	2538990	2539634	-	DDB_G0279773	DDB_G0279773_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr3	2539790	2539871	-	DDB_G0295153	tRNA-Ser-AGA-8	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2540030	2543877	-	DDB_G0279775	DDB_G0279775	NA
chr3	2544557	2545545	-	DDB_G0279781	DDB_G0279781_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0279775%22%3EDDB_G0279775%3C%2Fa%3E 
chr3	2546062	2546949	-	DDB_G0279783	DDB_G0279783	similar to bacterial short-chain dehydrogenase%2Freductase family proteins
chr3	2547350	2548238	-	DDB_G0279785	cniB	similar to human CNIH4 and S. pombe erv14%3B contains 3 predicted transmembrane domains
chr3	2553750	2554145	-	DDB_G0279855	mrps10	protein component of the small ribosomal subunit
chr3	2554628	2556009	+	DDB_G0279801	pex7	ortholog of peroxin 7%3B binds the peroxisome targeting signal type 2 (PTS2)%3B contains 6 WD40 repeats%3B mutations in human homolog cause a variety of peroxisomal disorders
chr3	2556336	2558174	+	DDB_G0279803	DDB_G0279803	NA
chr3	2558407	2559776	+	DDB_G0279805	DDB_G0279805	NA
chr3	2560881	2563234	+	DDB_G0279795	adamts	NA
chr3	2563367	2565484	-	DDB_G0279807	DDB_G0279807	NA
chr3	2569081	2570624	-	DDB_G0279799	cprB	NA
chr3	2572023	2575055	+	DDB_G0279809	DDB_G0279809	NA
chr3	2575486	2575797	-	DDB_G0279811	DDB_G0279811	NA
chr3	2578911	2581892	+	DDB_G0279813	DDB_G0279813	NA
chr3	2582186	2582632	-	DDB_G0279815	DDB_G0279815	contains a putative signal peptide and a C-terminal transmembrane domain
chr3	2583923	2584699	-	DDB_G0279817	DDB_G0279817	NA
chr3	2585071	2586279	-	DDB_G0279819	DDB_G0279819	NA
chr3	2586560	2588427	-	DDB_G0279821	DDB_G0279821	NA
chr3	2588778	2591702	-	DDB_G0279823	DDB_G0279823	NA
chr3	2593261	2597278	+	DDB_G0279825	DDB_G0279825	NA
chr3	2597532	2598965	-	DDB_G0279827	ivdA	catalyzes the reaction 3-methylbutanoyl-CoA %2B acceptor %3D 3-methylbut-2-enoyl-CoA %2B reduced acceptor
chr3	2599428	2600334	-	DDB_G0279829	DDB_G0279829	contains six putative transmembrane domains and is similar to DUF1295%2C a protein family of unknown function
chr3	2602496	2605546	+	DDB_G0279831	DDB_G0279831	putative protein serine%2Fthreonine kinase CAMK group%3B the protein kinase domain is similar to those of mammalian CAM kinase I
chr3	2605850	2606067	+	DDB_G0279833	colA_ps3	putative pseudogene%3B very small fragment similar to the large colossin A gene %3Ca href%3D%22%2Fgene%2FDDB_G0292696%22%3EcolA%3C%2Fa%3E
chr3	2606276	2607998	+	DDB_G0279835	DDB_G0279835	NA
chr3	2608266	2608922	-	DDB_G0279837	lsm1	member of a heteromeric complex containing lsm1-7 involved in mRNA degradation
chr3	2609748	2613314	+	DDB_G0306976	DDB_G0306976	similar to D. purpureum protein
chr3	2613814	2618034	+	DDB_G0306979	DDB_G0306979	conserved Dictyostelium protein%3B contains 2 EGF-like domains%3B contains both a predicted N-terminal signal sequence and C-terminal transmembrane domain
chr3	2618546	2622792	+	DDB_G0279859	DDB_G0279859	conserved Dictyostelium protein%3B contains 2 EGF-like domains%3B contains both a predicted N-terminal signal sequence and C-terminal transmembrane domain
chr3	2623274	2623344	-	DDB_G0295151	tRNA-His-GUG-7	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2623695	2624706	-	DDB_G0279797	ctnB	similar to countin (CtnA)
chr3	2627370	2628376	+	DDB_G0279843	DDB_G0279843	NA
chr3	2628470	2630968	-	DDB_G0279845	DDB_G0279845	NA
chr3	2631222	2631909	-	DDB_G0279847	expl4_ps	putative pseudogene%2C expansin-like family protein%2C similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth
chr3	2632482	2632553	+	DDB_G0295025	tRNA-Cys-GCA-4	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2633026	2634105	+	DDB_G0279861	DDB_G0279861_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	2634953	2637808	+	DDB_G0349761	DDB_G0349761_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	2638120	2639986	+	DDB_G0295687	dph2	similar to the conserved DPH2%2C which in %3Ci%3ES. cerevisiae%3C%2Fi%3E is required for synthesis of diphthamide%2C a modified histidine residue of translation elongation factor 2
chr3	2640159	2640778	-	DDB_G0279851	DDB_G0279851	putative histone acetyltransferase%3B highly similar to bacterial GCN5-related N-acetyltransferase (GNAT)
chr3	2641846	2645801	-	DDB_G0279863	DDB_G0279863	NA
chr3	2646397	2646933	-	DDB_G0279895	DDB_G0279895_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr3	2648228	2648539	-	DDB_G0279893	DDB_G0279893	%3Cb%3ECommunity annotation:%3C%2Fb%3E This appears to be a gene fragment resulting from degeneration of a member of a large family of uncharacterised Dictyostelium genes%2C which encode proteins containing B-box zinc fingers and FNIP repeats. Although it seems unlikely to encode a functional protein%2C its mRNA as found to be expressed and responsive: it was significantly down-regulated six hours after Legionella pneumophila infection in AX4 cells (Li et al.%2C Cell Host Microbe. 2009 Sep 17%3B6(3):253-67). A closely related%2C apparently intact gene%2C DDB_G0279871%2C is similarly down-regulated%2C suggesting a connection with the response to infection. %3Ci%3EGareth Bloomfield%2C December 2010%3C%2Fi%3E%3Cbr%3E
chr3	2648955	2650296	-	DDB_G0279891	DDB_G0279891	NA
chr3	2651015	2652371	-	DDB_G0279897	DDB_G0279897	NA
chr3	2653100	2654925	-	DDB_G0279889	DDB_G0279889_ps	putative pseudogene%3B similar to a conserved family of zinc finger %2F FNIP domain-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0279897%22%3EDDB_G0279897%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0279899%22%3EDDB_G0279899%3C%2Fa%3E
chr3	2656014	2657370	-	DDB_G0279899	DDB_G0279899	NA
chr3	2658208	2659559	-	DDB_G0279885	DDB_G0279885_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0278909%22%3EDDB_G0278909%3C%2Fa%3E
chr3	2659791	2661494	-	DDB_G0279881	DDB_G0279881_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0279897%22%3EDDB_G0279897%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0279873%22%3EDDB_G0279873%3C%2Fa%3E
chr3	2661756	2663115	-	DDB_G0279879	DDB_G0279879	NA
chr3	2664394	2665872	-	DDB_G0279877	DDB_G0279877	NA
chr3	2668171	2669593	-	DDB_G0279901	DDB_G0279901	NA
chr3	2670350	2671723	-	DDB_G0279873	DDB_G0279873	similar to D. purpureum protein
chr3	2672370	2673666	-	DDB_G0279871	DDB_G0279871	member of a large D. discoideum gene family that seems to be more diverse and not so expanded in D. purpureum and P. pallidum%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Significantly down-regulated after infection with Legionella pneumophila and underexpressed in uninfected dupA mutants (Li et al. Cell Host Microbe. 2009 Sep 17%3B6(3):253-67). %3Ci%3EGareth Bloomfield%2C December 2010%3C%2Fi%3E%3Cbr%3E
chr3	2675536	2675607	-	DDB_G0295149	tRNA-Glu-UUC-12	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr3	2675830	2677164	+	DDB_G0279867	DDB_G0279867_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	2678219	2679731	+	DDB_G0279903	wdr12	ortholog of mammalian wdr12 and yeast YTM1
chr3	2680036	2680911	+	DDB_G0279905	DDB_G0279905	NA
chr3	2681663	2682741	+	DDB_G0279907	DDB_G0279907	shares a short region of similarity with a D. purpureum gene
chr3	2683915	2687604	-	DDB_G0305565	DDB_G0305565_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr3	2688175	2691897	+	DDB_G0305714	DDB_G0305714_RTE	ORF2 protein encoding reverse transcriptase (RT) and integrase (IN) of long terminal repeat retrotransposon Skipper%3B refer to Genbank AF049230 for full-length element
chr3	2692188	2696215	+	DDB_G0280011	DDB_G0280011_TE	complex cluster of transposon fragments%2C contains TRE3-A ORF2 and an ORF for DDT-A
chr3	2697801	2699162	+	DDB_G0279929	DDB_G0279929_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	2700535	2700607	-	DDB_G0295147	tRNA-Ile-AAU-9	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2701058	2702968	+	DDB_G0279931	DDB_G0279931_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr3	2703861	2705657	-	DDB_G0279933	DDB_G0279933	NA
chr3	2706627	2707106	+	DDB_G0280013	hspM	 
chr3	2707384	2708017	+	DDB_G0279935	DDB_G0279935	contains one C2 domain%2C which is is a Ca2%2B-dependent membrane-targeting module found in many cellular proteins involved in signal transduction or membrane trafficking%3B contains a predicted peroxisomal targeting signal
chr3	2708291	2711614	-	DDB_G0279937	DDB_G0279937	NA
chr3	2713196	2716121	+	DDB_G0279927	Dd5P1	NA
chr3	2716529	2716884	-	DDB_G0279939	DDB_G0279939	conserved in plants and fungi%3B contains one putative transmembrane domain
chr3	2718242	2721164	-	DDB_G0279941	DDB_G0279941	NA
chr3	2721717	2723556	-	DDB_G0279943	DDB_G0279943	belongs to the major facilitator superefamily%3B contains 12 putative transmembrane domains
chr3	2725463	2730232	+	DDB_G0279913	dhkH	NA
chr3	2734597	2736770	+	DDB_G0279909	lipA	similar to arachidonate 12-lipoxygenase%2C which catalyzes the reaction arachidonate %2B O%3Csub%3E2%3C%2Fsub%3E %3D (5Z%2C8Z%2C10E%2C14Z)-(12S)-12-hydroperoxyicosa-5%2C8%2C10%2C14-tetraenoate %3B enriched in gametes%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FLipA%22%3Ecommunity annotation%3C%2Fa%3E
chr3	2737032	2739323	-	DDB_G0279945	DDB_G0279945	NA
chr3	2739612	2739772	-	DDB_G0295549	rnu1b	component of the spliceosome involved in pre-mRNA splicing
chr3	2740248	2741470	+	DDB_G0279911	ndkM	catalyzes the phosphorylation of nucleoside or deoxynucleoside diphosphates into the corresponding triphosphates
chr3	2741741	2742387	-	DDB_G0279949	DDB_G0279949	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr3	2743413	2743976	-	DDB_G0279951	DDB_G0279951	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr3	2745400	2745473	+	DDB_G0295027	tRNA-Val-AAC-13	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2745921	2747384	-	DDB_G0279953	DDB_G0279953	NA
chr3	2748541	2749904	+	DDB_G0279955	DDB_G0279955	NA
chr3	2750436	2751954	-	DDB_G0279957	DDB_G0279957	NA
chr3	2752719	2754560	-	DDB_G0279925	mlkA	CAMK1 family protein kinase%2C phosphorylates the myosin II regulatory light chain at S13%3B is not regulated by Ca2%2B%2Fcalmodulin
chr3	2758242	2759567	+	DDB_G0279959	eco1	ortholog of S. cerevisiae ECO1%2C an acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation: %3C%2Fb%3E The involvement of DDB_G0279959 in Dicty cell cycle progression is supported by its 7-fold overexpression in a Dictyostelium %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA mutant%3C%2Fa%3E strain lacking the Dicty retinoblastoma-like gene (Doquang et al%2C in preparation). The rblA-knockout strain overexpresses most genes involved in mitosis and DNA replication%2C but relatively few other genes. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr3	2759596	2762072	-	DDB_G0279915	abcB4	half transporter%2C consisting of one ABC domain and one transmembrane domain%3B serves as an anchor for the calcium-dependent cell-cell adhesion protein CadA
chr3	2762286	2763560	+	DDB_G0279961	drpp40	protein subunit of both the RNase P complex involved in tRNA processing and the RNase MRP complex involved in rRNA processing
chr3	2763788	2763948	+	DDB_G0294411	rnu1a	component of the spliceosome involved in pre-mRNA splicing
chr3	2764702	2766927	+	DDB_G0280015	DDB_G0280015	NA
chr3	2767341	2767750	-	DDB_G0279963	DDB_G0279963	NA
chr3	2769281	2771836	-	DDB_G0279919	abcD3	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr3	2772102	2774570	-	DDB_G0279917	abcD1	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr3	2775437	2776753	-	DDB_G0279965	DDB_G0279965	members of the NAD-dependent epimerase%2Fdehydratase family use nucleotide-sugar substrates for a variety of chemical reactions%3B contains a putative signal peptide
chr3	2777162	2779633	-	DDB_G0279921	gp130	contains amino terminal membrane insertion signal and carboxy terminal sequences for addition of lipid anchor%3B involved in pinocytosis
chr3	2780826	2781737	+	DDB_G0279967	DDB_G0279967	conserved eukaryotic protein
chr3	2781830	2784109	-	DDB_G0279969	DDB_G0279969	NA
chr3	2784977	2786706	-	DDB_G0279923	apnA	breaks the C-O-P bond 5%27 to an apurinic or apyrimidinic site in DNA %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E ApnA has a canonical PCNA-interacting domain%2C also known as a PIP sequence%2C  in this case QtsItdFF. For a discussion of PIP domains%2C (see Supplementary table 1 in  %3Ca href%3D%22http:%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F17512402%22%3EMoldovan et al%2C 2007%3C%2Fa%3E). This suggests that apnA may be involved in a  base excision repair pathway which is immediately coupled to DNA replication (ibid).  Concordant with this is the fact that the gene is tenfold overexpressed in a  Dicty strain deficient in the Dicty retinoblastoma-like gene rblA (Doquang et al%2C  in preparation). Most genes whose products are involved in cell cycle progression  are overexpressed in this strain. The glycosylase MYH (6-fold overexpressed%2C  which also contains a possible PIP sequence) may likewise be part of the  replication-couple NER pathway. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E
chr3	2788130	2795336	+	DDB_G0280017	DDB_G0280017	NA
chr3	2796272	2796973	+	DDB_G0280019	DDB_G0280019	conserved in bacteria and fungi%3B similar to S. cerevisiae HSP31 (heat shock protein 31)%2C a putative protease
chr3	2797799	2798764	+	DDB_G0280021	mcfL	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane 
chr3	2799462	2800655	-	DDB_G0279971	DDB_G0279971	NA
chr3	2800822	2801370	-	DDB_G0279973	DDB_G0279973	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr3	2802732	2804726	-	DDB_G0279975	DDB_G0279975	NA
chr3	2805237	2806119	+	DDB_G0279977	bud32	belongs to the Bud32 family%3B highly similar in sequence and length to yeast BUD32 and mammalian PRPK (p53-related protein kinase)
chr3	2806294	2808540	-	DDB_G0279979	DDB_G0279979	contains no functional domains and is not similar to any other protein
chr3	2809171	2810082	+	DDB_G0279981	DDB_G0279981	NA
chr3	2810254	2810508	-	DDB_G0280023	DDB_G0280023	NA
chr3	2813758	2816058	+	DDB_G0279983	ctrB	similar to mammalian SLC7A1-4 (solute carrier family 7%2C members 1 to 4)%3B multi-pass membrane protein%2C contains 14 predicted transmembrane domains
chr3	2817297	2820496	+	DDB_G0279985	DDB_G0279985	conserved hypothetical protein%3B contains a signal peptide and two predicted transmembrane domains
chr3	2820923	2821597	+	DDB_G0279987	DDB_G0279987	NA
chr3	2821744	2823688	-	DDB_G0280025	DDB_G0280025	NA
chr3	2823865	2824446	+	DDB_G0279989	DDB_G0279989	NA
chr3	2824517	2827436	-	DDB_G0279991	exoc8	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr3	2827799	2829409	-	DDB_G0294619	DDB_G0294619	NA
chr3	2829765	2830413	-	DDB_G0302676	DDB_G0302676	NA
chr3	2832531	2832695	-	DDB_G0279993	DDB_G0279993	NA
chr3	2833406	2836050	-	DDB_G0279995	DDB_G0279995	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages
chr3	2837555	2838534	+	DDB_G0279997	rpl18	protein component of the large (60S) ribosomal subunit
chr3	2841134	2844877	+	DDB_G0279999	DDB_G0279999	contains 3 EGF-like domains%3B contains a predicted signal peptide and a C-terminal transmembrane domain
chr3	2845223	2848982	+	DDB_G0280001	DDB_G0280001	NA
chr3	2849525	2853250	+	DDB_G0280003	DDB_G0280003	NA
chr3	2854428	2858358	+	DDB_G0280029	DDB_G0280029_ps	putative pseudogene%3B similar to a large D. discoideum gene family%2C including%2C %3Ca href%3D%22%2Fgene%2FDDB_G0279999%22%3EDDB_G0279999%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0280001%22%3EDDB_G0280001%3C%2Fa%3E
chr3	2860281	2863067	+	DDB_G0280005	DDB_G0280005_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0279999%22%3EDDB_G0279999%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0280001%22%3EDDB_G0280001%3C%2Fa%3E
chr3	2864348	2867566	-	DDB_G0280007	DDB_G0280007	NA
chr3	2870918	2874097	-	DDB_G0280031	DDB_G0280031_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	2876124	2876197	-	DDB_G0295145	tRNA-Arg-ACG-7	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr3	2877474	2878034	+	DDB_G0280365	DDB_G0280365_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	2879114	2880324	+	DDB_G0280063	DDB_G0280063	NA
chr3	2880772	2885193	+	DDB_G0280065	DDB_G0280065	NA
chr3	2886853	2888403	+	DDB_G0280067	DDB_G0280067	similar to T-cell activation protein phosphatase 2C%3B the protein phosphatase 2C-related domain occurs in protein phosphatase 2C (PPC2) as well as in other proteins%2C such as pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase
chr3	2889026	2890227	-	DDB_G0280069	DDB_G0280069	NA
chr3	2891601	2894057	+	DDB_G0280071	DDB_G0280071	NA
chr3	2894240	2895662	-	DDB_G0280073	DDB_G0280073	NA
chr3	2895929	2897515	-	DDB_G0280075	DDB_G0280075	NA
chr3	2898485	2899062	+	DDB_G0280077	bloc1s1	ortholog of human BLOC1S1%3B component of the BLOC-1 complex that is required for normal biogenesis of lysosome-related organelles
chr3	2899122	2902089	-	DDB_G0280079	ada2	C-terminal half has similarity to the histone acetyltransferase complex component of Zea mays %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation%3C%2Fb%3E: DDB_G0280079 codes for a protein with significant homologies to the transcriptional ADAptor subunit ADA2 of budding yeast. Yeast ADA2 participates in several complexes together with the histone acetyl transferase GCN5%2C which also has an ortholog in Dicty. DDB_GO280079 appears likely to be cell-cycle regulated in Dicty%2C as it is threefold overexpressed in a strain in which the Dicty Rb ortholog rblA has been disrupted.In addition%2C DDB_G0280079 shows a developmental trajectory similar to those of most genes involved in cell cycle progression (see DictyExpress). Finally%2C the promoter contains an element (GCGCCCAAA) which is highly enriched in the promoters of Dictyostelium cell cycle genes. %3Ci%3EHarry MacWilliams%2C June 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Fada2%22%3E There is more information on the wiki page%3C%2Fa%3E
chr3	2902757	2906284	+	DDB_G0280081	exoc2	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr3	2907001	2908252	+	DDB_G0280083	mcfJ	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr3	2908403	2909200	-	DDB_G0280085	DDB_G0280085	expressed in prespore cells
chr3	2911297	2915408	+	DDB_G0280087	gxcS	NA
chr3	2915769	2917228	-	DDB_G0280089	DDB_G0280089	contains one C3HC4-type (RING finger) zinc-finger domain
chr3	2917996	2919019	+	DDB_G0280367	DDB_G0280367	similar to D. purpureum protein
chr3	2919337	2920234	-	DDB_G0280091	DDB_G0280091	homolog of human UBE2H (ubiquitin-conjugating enzyme E2 H) and S. pombe ubc8%3B catalyzes the covalent attachment of ubiquitin to other proteins
chr3	2921032	2922532	-	DDB_G0280053	osbA	interacts with STATc%3B enriched in pstO cells%3B inactivation leads to a slugger phenotype
chr3	2923710	2927475	-	DDB_G0280093	gacGG	NA
chr3	2928904	2929627	-	DDB_G0280095	DDB_G0280095	NA
chr3	2930052	2931684	-	DDB_G0280097	DDB_G0280097	contains a signal peptide%2C a weak PA14 domain%2C and 2 %3Ci%3EDictyostelium%3C%2Fi%3E-specific repeats
chr3	2932544	2934292	-	DDB_G0280099	DDB_G0280099_ps	putative pseudogene%2C similar to DDB_G0280097
chr3	2934621	2935922	-	DDB_G0280101	DDB_G0280101_ps	putative pseudogene%3B similar to Dictyostelium PA14 domain-containing proteins
chr3	2937406	2937942	+	DDB_G0280103	DDB_G0280103	similar to Polysphondylium pallidum hypothetical proteins
chr3	2938222	2940089	-	DDB_G0280105	DDB_G0280105	catalyzes the preferential release of a C-terminal arginine or lysine residue%3B expressed in pstAB cells and in upper cup during culmination
chr3	2940647	2940717	+	DDB_G0295029	tRNA-Gly-GCC-4	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	2941138	2941661	-	DDB_G0280107	DDB_G0280107	NA
chr3	2942956	2947600	-	DDB_G0280369	DDB_G0280369	NA
chr3	2948262	2948693	+	DDB_G0280109	med11	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 11%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr3	2948944	2952761	-	DDB_G0280111	DDB_G0280111	putative protein serine%2Fthreonine kinase%3B similar to the kinase domains of AAK1 (AP2 associated kinase) and BMP-inducible protein kinase (BIKe)
chr3	2954586	2955002	+	DDB_G0280061	sybA	regulated by the MADS-box transcription factor SrfA during development
chr3	2955422	2958552	-	DDB_G0280113	anapc5	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr3	2958706	2960307	-	DDB_G0280115	DDB_G0280115	contains 2 FNIP repeats
chr3	2961104	2965064	+	DDB_G0280117	DDB_G0280117	NA
chr3	2965418	2968512	-	DDB_G0280047	yelA	involved in the regulation of terminal differentiation
chr3	2971976	2976291	-	DDB_G0280119	DDB_G0280119	NA
chr3	2976788	2977787	-	DDB_G0280121	DDB_G0280121	similar to human ZMAT2%2C zinc finger matrin type 2 and yeast SNU23%2C a component of the U4%2FU6.U5 snRNP involved in mRNA splicing
chr3	2978017	2978724	+	DDB_G0280123	DDB_G0280123	NA
chr3	2979381	2983277	+	DDB_G0280125	DDB_G0280125	NA
chr3	2983397	2984706	-	DDB_G0280127	map1d	releases  N-terminal amino acids%2C preferentially methionine%2C from peptides and arylamides%3B ortholog of the human mitochondrial MAPD1
chr3	2984895	2985253	+	DDB_G0280129	DDB_G0280129	NA
chr3	2985578	2989509	-	DDB_G0280131	DDB_G0280131	member of the TKL (tyrosine kinase-like) group and the ARMK (armadillo repeat-containing kinase) family%3B contains armadillo%2Fbeta-catenin-like repeats%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr3	2991402	2996437	+	DDB_G0280133	DDB_G0280133	CAMK family protein kinase%3B protein kinase domain similar to those of mammalian SNF1 like kinases
chr3	2996500	2997587	-	DDB_G0280135	DDB_G0280135	NA
chr3	2997946	2999037	-	DDB_G0280137	DDB_G0280137	NA
chr3	2999177	2999542	+	DDB_G0280139	DDB_G0280139	NA
chr3	3002773	3004711	+	DDB_G0280141	DDB_G0280141	NA
chr3	3004846	3007140	-	DDB_G0280143	DDB_G0280143	accessory component of Rab geranylgeranyltransferase that is crucial for the membrane association and function of Rab proteins
chr3	3007522	3009141	-	DDB_G0280371	DDB_G0280371	homolog of human GK and S. cerevisiae GUT1 (glycerol utilization)%3B catalyzes the reaction ATP %2B glycerol %3D ADP %2B sn-glycerol 3-phosphate
chr3	3009655	3010347	-	DDB_G0280373	DDB_G0280373	conserved in fungi and plants
chr3	3010631	3012067	+	DDB_G0280041	pyr56	bifunctional enzyme that catalyzes the reactions PRPP %2B orotate %3C%3D%3E orotidine-5%27-phosphate %2B pyrophosphate and orotidine-5%27-phosphate %3C%3D%3E CO%3Csub%3E2%3C%2Fsub%3E %2B UMP in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine ribonucleotides
chr3	3012864	3015761	+	DDB_G0280145	DDB_G0280145	member of the glycosyl hydrolase family 63 that  catalyses the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2)
chr3	3015956	3017596	-	DDB_G0280147	ddx47	ortholog of H. sapiens DDX47 and S. cerevisiae RRP3 (Ribosomal RNA Processing 3)
chr3	3018896	3023239	-	DDB_G0280149	DDB_G0280149	NA
chr3	3024229	3024918	+	DDB_G0280153	DDB_G0280153	NA
chr3	3025070	3026700	-	DDB_G0280155	DDB_G0280155_ps	putative pseudogene%3B fragment%2C similar to the neighboring genes %3Ca href%3D%22%2Fgene%2FDDB_G0280149%22%3EDDB_G0280149%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0280157%22%3EDDB_G0280157%3C%2Fa%3E
chr3	3027046	3031543	-	DDB_G0280157	DDB_G0280157	NA
chr3	3031994	3034836	-	DDB_G0280159	DDB_G0280159	one of three paralogs in %3Ci%3EDictyostelium%3C%2Fi%3E (other genes: %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283989%22%3E%3Ci%3EDDB_G0283989%3C%2Fi%3E%3C%2Fa%3E) that are putative hydrolases
chr3	3035184	3036248	-	DDB_G0280161	mcfK	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr3	3036716	3038045	+	DDB_G0280163	DDB_G0280163	NA
chr3	3038985	3041507	+	DDB_G0280165	DDB_G0280165	NA
chr3	3041998	3044830	+	DDB_G0280167	psiO	contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 7 Dictyostelium (CTDC) repeats%2C and a carboxyl terminal transmembrane domain 
chr3	3046316	3049419	+	DDB_G0280171	psiP	contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 4 Dictyostelium (CTDC) repeats and a C-terminal transmembrane domain
chr3	3050099	3050794	+	DDB_G0280173	isca1	conserved protein involved in the assembly of mitochondrial iron-sulfur proteins
chr3	3050941	3052942	-	DDB_G0280175	dynD	ortholog of dynactin 4
chr3	3054033	3057877	+	DDB_G0280177	DDB_G0280177	NA
chr3	3058313	3059360	+	DDB_G0280179	elmoB	similar to H. sapiens ELMOD1 and ELMOD2
chr3	3060646	3060718	+	DDB_G0295031	tRNA-Asn-GUU-12	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr3	3061638	3066824	+	DDB_G0280375	DDB_G0280375	NA
chr3	3067276	3068277	-	DDB_G0280181	DDB_G0280181	contains three ankyrin repeats and an RA domain%2C which plays a role in RasGTP activation in mammals and mating in yeast%3B highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284079%22%3E%3Ci%3EDDB_G0284079%3C%2Fi%3E%3C%2Fa%3E
chr3	3069484	3071171	+	DDB_G0280183	sglB	catalyzes the reaction sphinganine 1-phosphate %3C%3D%3E phosphoethanolamine %2B palmitaldehyde
chr3	3071897	3074445	+	DDB_G0280377	DDB_G0280377	NA
chr3	3074704	3076362	+	DDB_G0280379	DDB_G0280379	NA
chr3	3076448	3077678	-	DDB_G0280185	DDB_G0280185	conserved hypothetical protein%3B contains a putative signal peptide
chr3	3078456	3080086	+	DDB_G0280187	DDB_G0280187	similar to cathepsin Z%2C a papain cysteine protease family protein
chr3	3081325	3082617	+	DDB_G0280189	DDB_G0280189	NA
chr3	3082696	3084110	-	DDB_G0280191	DDB_G0280191	NA
chr3	3084374	3086922	-	DDB_G0280193	DDB_G0280193	NA
chr3	3087742	3093065	-	DDB_G0280195	hdaC	catalyzes the removal of an acetyl group from lysine
chr3	3095673	3097226	+	DDB_G0280197	sepsecs	converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
chr3	3097322	3098826	-	DDB_G0280199	gadA	catalyzes the reaction L-glutamate %3C%3D%3E 4-aminobutanoate %2B CO%3Csub%3E2%3C%2Fsub%3E%3B expressed during development and enriched in prespore cells
chr3	3099615	3100367	-	DDB_G0280201	DDB_G0280201	conserved hypothetical protein%3B contains a putative signal peptide
chr3	3101331	3102263	+	DDB_G0280203	DDB_G0280203_ps	putative pseudogene%3B similar to pirin family proteins%2C especially to DDB_G0281115 and DDB_G0280725
chr3	3102884	3102956	-	DDB_G0295143	tRNA-Arg-UCU-10	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr3	3103912	3105333	-	DDB_G0280037	ddj1	DnaJ homolog with dual localization in the cytoplasm and cortex
chr3	3106631	3109388	-	DDB_G0280205	DDB_G0280205	NA
chr3	3109725	3114793	-	DDB_G0280209	DDB_G0280209	similar to RNA polymerase II associated proteins (yeast RPA50 and human RPAP1)
chr3	3115387	3116136	-	DDB_G0280211	DDB_G0280211	NA
chr3	3118643	3120514	+	DDB_G0280383	DDB_G0280383	NA
chr3	3121269	3122626	+	DDB_G0280215	DDB_G0280215	large molecular weight protein that contains a hsp20 domain
chr3	3122881	3123172	-	DDB_G0280217	DDB_G0280217	NA
chr3	3124645	3127046	-	DDB_G0280057	grp94	NA
chr3	3127670	3128628	-	DDB_G0280219	vps55	highly similar to yeast VPS55 (vacuolar protein sorting 55) and human LEPROTL1 (leptin receptor overlapping transcript-like 1)
chr3	3129179	3135878	-	DDB_G0280221	DDB_G0280221	NA
chr3	3136945	3137848	-	DDB_G0280223	iliF	induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr3	3138804	3139214	+	DDB_G0280225	DDB_G0280225	similar to conserved hypothetical proteins%3B expressed in pstO cells and upper cup during culmination
chr3	3139657	3141535	-	DDB_G0280227	DDB_G0280227	NA
chr3	3141943	3142654	+	DDB_G0280229	rpl24	protein component of the large (60S) ribosomal subunit
chr3	3143611	3143692	+	DDB_G0295033	tRNA-Ser-AGA-7	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	3143880	3144302	+	DDB_G0280231	DDB_G0280231_ps	putative pseudogene%3B fragment%2C similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0287389%22%3EDDB_G0287389%3C%2Fa%3E
chr3	3144889	3146310	+	DDB_G0280233	DDB_G0280233	NA
chr3	3146638	3148177	-	DDB_G0280235	DDB_G0280235	A. thaliana and S. pombe orthologs are found in the endoplasmic reticulum
chr3	3148507	3149553	+	DDB_G0280237	coq5	S-adenosyl-L-methionine (SAM)-dependent methyltransferase%3B methylates quinones: in E. coli: demethylmenaquinone and 2-octaprenyl-6-methoxy-1%2C4-benzoquinone%2C and in S. cerevisiae: 2-hexaprenyl-6-methoxy-1%2C4-benzoquinone%3B the substrates of this enzyme in Dictyostelium are not known.
chr3	3149782	3150495	+	DDB_G0280399	tmem93	conserved protein
chr3	3151038	3152966	+	DDB_G0280239	DDB_G0280239	has a short region of similarity with CARD4 (caspase recruitment domain family%2C member 4)
chr3	3153116	3153869	-	DDB_G0280241	DDB_G0280241	NA
chr3	3154238	3155321	-	DDB_G0280243	DDB_G0280243	NA
chr3	3156312	3157836	+	DDB_G0280385	DDB_G0280385	NA
chr3	3158659	3159132	-	DDB_G0280245	ecmL	NA
chr3	3159963	3161380	-	DDB_G0280247	DDB_G0280247	NA
chr3	3162671	3165464	-	DDB_G0280249	ase1A	member of the MAP65%2FASE1 family of microtubule associated proteins%3B ortholog of human PRC1 and yeast ASE1%3B loss of ase1A produces a disruption to the spindle midzone during division%2C and ase1A also appears to play a role during interphase to exclude or minimize interdigitating microtubules of opposite polarity %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E The provisional identification of this gene as Ase1 is supported by its threefold overexpression in a Dicty strain lacking the Dicty retinoblastoma-like gene rblA (Doquang et al%2C in preparation). Most genes whose products are involved in cell cycle progression are overexpressed in this strain. %3Cbr%2F%3E Ase1 is a microtubule associated protein%2C resident in the midbody of the mitotic spindle%3B it is phosphorylated by cdk1 during mitotic entry%2C dephosphorylated by the mitotic-exit specific phosphatase cdc14%2C and degraded by the anaphase promoting complex (see Khmelinskii and Schiebel%2C Cell Cycle 7%2C 283-6 (2008). In budding yeast%2C ase1 is required for spindle elongation and stabilization. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr3	3165971	3166945	-	DDB_G0280251	DDB_G0280251	similar to human EXOSC7%2C which is a component of the exosome%2C a 3%27-5%27 exoribonuclease complex involved in RNA processing
chr3	3167632	3171153	+	DDB_G0280253	DDB_G0280253	NA
chr3	3171359	3172577	-	DDB_G0280255	mdhC	catalyzes the reaction malate %2B NAD %3C%3D%3E oxaloacetate %2B NADH
chr3	3173383	3174731	+	DDB_G0280257	DDB_G0280257	NA
chr3	3175236	3176238	+	DDB_G0280045	thyA	catalyzes the reaction 5%2C10-methylenetetrahydrofolate %2B dUMP %2B FADH%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E dTMP %2B tetrahydrofolate %2B FAD in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine deoxyribonucleotides
chr3	3176428	3178260	-	DDB_G0280259	DDB_G0280259	NA
chr3	3178567	3180486	-	DDB_G0280261	DDB_G0280261	contains one LisH domain and 7 WD40 domains%3B similar to human TBL1X (F-box-like%2FWD repeat-containing protein) which plays a role in transcription activation mediated by nuclear receptors
chr3	3180987	3182048	-	DDB_G0280263	DDB_G0280263	NA
chr3	3182303	3182845	+	DDB_G0280265	DDB_G0280265	NA
chr3	3183979	3185311	+	DDB_G0280267	allC	catalyzes the reaction allantoate %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E (S)-ureidoglycolate %2B urea in allantoin degradation
chr3	3188254	3190056	+	DDB_G0280059	rhgB	contains 10 transmembrane domains
chr3	3190136	3192063	-	DDB_G0280269	DDB_G0280269	NA
chr3	3192876	3193504	+	DDB_G0280271	DDB_G0280271	conserved in amoeba%2C fungi and alveolates
chr3	3194120	3194593	+	DDB_G0294499	staB	expressed in prestalk cells and in the basal disc during culmination%3B highly similar to staA
chr3	3195244	3195458	+	DDB_G0280387	DDB_G0280387	NA
chr3	3196112	3196585	+	DDB_G0294473	staA	DIF-inducible%3B highly similar to staB
chr3	3197151	3197337	+	DDB_G0280389	DDB_G0280389	NA
chr3	3198023	3198496	+	DDB_G0280277	DDB_G0280277	NA
chr3	3199016	3199294	+	DDB_G0280279	DDB_G0280279	NA
chr3	3200265	3202279	+	DDB_G0280281	DDB_G0280281	NA
chr3	3203048	3206382	+	DDB_G0280283	DDB_G0280283	NA
chr3	3206520	3207210	+	DDB_G0280285	DDB_G0280285	weakly similar to ints8%2C component of a multiprotein mediator of small nuclear RNA processing
chr3	3207518	3208475	-	DDB_G0280287	DDB_G0280287	NA
chr3	3208817	3211777	-	DDB_G0280289	DDB_G0280289	NA
chr3	3212417	3214010	+	DDB_G0280291	DDB_G0280291	bifunctional enzyme that catalyzes the reactions methylene-tetrahydrofolate %2B NADP %3C%3D%3E NADPH %2B methenyl-H%3Csub%3E4%3C%2Fsub%3EF and NADPH %2B methenyl-H%3Csub%3E4%3C%2Fsub%3EF %3C%3D%3E methylene-tetrahydrofolate %2B NADP
chr3	3214568	3216167	+	DDB_G0280293	coq1	adds prenyl units to all-trans-polyprenyl diphosphate%3B similar to S. cerevisiae COQ1%2C which catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
chr3	3217053	3217685	+	DDB_G0280295	DDB_G0280295_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0273357%22%3EDDB_G0273357%3C%2Fa%3E 
chr3	3219540	3221021	+	DDB_G0280299	DDB_G0280299	NA
chr3	3222079	3223044	-	DDB_G0280303	DDB_G0280303_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0284189%22%3EDDB_G0284189%3C%2Fa%3E
chr3	3223200	3223352	-	DDB_G0280305	DDB_G0280305	NA
chr3	3224159	3227470	-	DDB_G0280039	myoA	actin-based motor%3B unconventional myosin heavy chain
chr3	3228229	3229981	-	DDB_G0280307	DDB_G0280307	contains a predicted signal peptide
chr3	3230743	3235078	-	DDB_G0280055	abcC2	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr3	3235987	3238812	-	DDB_G0280309	mcm3	similar to MCM3%2C a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
chr3	3240109	3240645	+	DDB_G0280391	DDB_G0280391	NA
chr3	3241213	3244547	+	DDB_G0280311	DDB_G0280311	NA
chr3	3245211	3246276	-	DDB_G0280313	ssr2	subunit of the TRAP complex aids in the translocation of nascent polypeptides into the lumen of the endoplasmic reticulum
chr3	3247016	3247990	-	DDB_G0280315	DDB_G0280315	NA
chr3	3248423	3249124	-	DDB_G0280317	DDB_G0280317	catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione
chr3	3249762	3253025	-	DDB_G0280319	glud2	highly similar to fungal glutamate dehydrogenases%3B catalyzes the reaction L-glutamate %2B H%3Csub%3E2%3C%2Fsub%3EO %2B NAD(P)%3Csup%3E%2B%3C%2Fsup%3E %3D 2-oxoglutarate %2B ammonia %2B NAD(P)H %2B H%3Csup%3E%2B%3C%2Fsup%3E%3B expressed in pstO cells and upper cup during culmination
chr3	3254509	3256772	+	DDB_G0280393	DDB_G0280393	NA
chr3	3257414	3260047	+	DDB_G0280321	fhkE	CAMK group%2C RAD53 family protein kinase%3B similar to mammalian cell cycle checkpoint kinases chk2%3B contains a forkhead-associated (FHA) domain%2C a phosphopeptide recognition domain found in many regulatory proteins
chr3	3260852	3261084	-	DDB_G0280323	DDB_G0280323	contains no functional domains and is not similar to any other protein
chr3	3261453	3261741	-	DDB_G0280325	DDB_G0280325	NA
chr3	3262207	3262533	-	DDB_G0280327	DDB_G0280327	NA
chr3	3262966	3264093	+	DDB_G0280329	DDB_G0280329	contains a DHHC type zinc finger believed to be involved in protein-protein or protein-DNA interactions
chr3	3265565	3265711	+	DDB_G0280331	DDB_G0280331	NA
chr3	3266503	3267523	+	DDB_G0280043	rab8A	regulates contractile vacuole discharging in response to osmotic stress%3B regulated by %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0280955%22%3Edisgorgin%3C%2Fa%3E
chr3	3268225	3270369	-	DDB_G0280395	DDB_G0280395_ps	putative pseudogene%3B similar to EGF-like domain-containing protein such as %3Ca href%3D%22%2Fgene%2FDDB_G0290285%22%3EDDB_G0290285%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0277603%22%3EDDB_G0277603%3C%2Fa%3E
chr3	3271724	3274972	+	DDB_G0280397	DDB_G0280397	NA
chr3	3275255	3275947	-	DDB_G0280333	DDB_G0280333	NA
chr3	3276492	3277024	-	DDB_G0280335	DDB_G0280335	NA
chr3	3277418	3277913	-	DDB_G0280337	DDB_G0280337	NA
chr3	3278339	3279326	-	DDB_G0280339	DDB_G0280339	NA
chr3	3280488	3280946	+	DDB_G0280049	rdiB	NA
chr3	3281113	3282389	-	DDB_G0280051	DDB_G0280051	NA
chr3	3283772	3284320	+	DDB_G0280341	DDB_G0280341	NA
chr3	3284706	3285911	+	DDB_G0280343	DDB_G0280343	NA
chr3	3286144	3287386	-	DDB_G0280345	sgtA	ortholog of a conserved protein of unknown function (sgtA in H. sapiens)
chr3	3287782	3288431	+	DDB_G0280347	DDB_G0280347	similar to ubiquitin-conjugating enzyme E2G 2
chr3	3288732	3289517	-	DDB_G0280349	DDB_G0280349	NA
chr3	3291770	3293372	+	DDB_G0280351	gpaL	NA
chr3	3293945	3296736	+	DDB_G0280353	odhA	catalyzes the reaction 2-oxoglutarate %2B [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine %3D [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine %2B CO%3Csub%3E2%3C%2Fsub%3E%3B E1 component of the multienzyme 2-oxoglutarate dehydrogenase complex
chr3	3299810	3300837	+	DDB_G0280357	DDB_G0280357	NA
chr3	3309264	3310324	+	DDB_G0280403	bloc1s4	ortholog of human BLOC1S4%2C a component of the BLOC-1 complex
chr3	3310609	3311235	-	DDB_G0280405	DDB_G0280405	NA
chr3	3312082	3314385	+	DDB_G0280407	ddx56	ortholog of H. sapiens DDX56 and S. cerevisiae DBP9 (Dead Box Protein 9)%3B involved in biogenesis of the 60S ribosomal subunit
chr3	3314622	3316241	-	DDB_G0280409	DDB_G0280409	NA
chr3	3316821	3317345	-	DDB_G0280401	cypD	NA
chr3	3317501	3318841	+	DDB_G0280411	DDB_G0280411	belongs to the anaerobic coproporphyrinogen-III oxidase family%3B similar to human RSAD1
chr3	3319399	3322888	+	DDB_G0280413	DDB_G0280413	NA
chr3	3323965	3324460	+	DDB_G0280415	DDB_G0280415	weak similarity to profilin%2Fallergen HMM%3B similar to D. purpureum protein
chr3	3324590	3325577	-	DDB_G0280417	DDB_G0280417	similar to D. purpureum protein
chr3	3326559	3329126	+	DDB_G0280419	DDB_G0280419	NA
chr3	3329289	3330048	-	DDB_G0280421	DDB_G0280421	NA
chr3	3330748	3332198	+	DDB_G0280423	DDB_G0280423	NA
chr3	3332494	3333718	-	DDB_G0280425	DDB_G0280425	NA
chr3	3335352	3338884	-	DDB_G0280427	ap4e1	NA
chr3	3339591	3343659	-	DDB_G0280429	DDB_G0280429	NA
chr3	3344181	3345988	-	DDB_G0280431	rio1	atypical%2C RIO family protein kinase%3B yeast serine%2Fthreonine kinase RIO1 plays a role in cell cycle progression
chr3	3347454	3347745	+	DDB_G0280433	DDB_G0280433	hypothetical protein%2C similar to the EST-supported %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284283%22%3E%3Ci%3EDDB_G0284283%3C%2Fi%3E%3C%2Fa%3E
chr3	3347902	3352629	-	DDB_G0280435	dynA	ortholog od dynactin 1
chr3	3353124	3354151	-	DDB_G0280437	DDB_G0280437	NA
chr3	3355162	3355449	-	DDB_G0280439	cpiB	similar to animal and plant cystatin A2%3B member of the stefin family of cysteine protease inhibitors
chr3	3356050	3356886	+	DDB_G0280441	DDB_G0280441	NA
chr3	3356914	3358497	-	DDB_G0280443	DDB_G0280443	contains 4 FNIP repeats%3B conserved in Dictyostelium
chr3	3359342	3363610	+	DDB_G0280521	DDB_G0280521_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr3	3364554	3365882	-	DDB_G0280523	DDB_G0280523_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	3366146	3366218	+	DDB_G0295035	tRNA-Gln-UUG-11	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr3	3367339	3367898	-	DDB_G0280445	DDB_G0280445	GFA enzymes catalyze the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione%3B all known members of this family contain 5 strongly conserved cysteine residues
chr3	3368362	3369914	-	DDB_G0280447	pelo	ortholog of the conserved %3Ci%3ED. melanogaster%3C%2Fi%3E protein pelota%2C which is required for spindle formation and nuclear envelope breakdown during spermatogenesis%2C and is proposed to act in protein translation.
chr3	3370546	3371762	-	DDB_G0280449	pitC	belongs to the phosphatidylinositol transfer protein family%2C similar to %3Ci%3EH. sapiens%3C%2Fi%3E membrane-associated phosphatidylinositol transfer proteins 1 and 2%2C but significantly smaller protein%3B very similar to %3Ci%3EDictyostelium%3C%2Fi%3E pitA and pitB
chr3	3372581	3373171	+	DDB_G0280451	DDB_G0280451	conserved protein%2C very similar to TR4 orphan receptor associated protein%3B containing a galactose-binding domain-like fold
chr3	3373444	3374418	-	DDB_G0280453	DDB_G0280453	conserved in Drosophila%3B predicted to have a structural domain found in several acyl-CoA acyltransferase enzymes
chr3	3375530	3378598	+	DDB_G0280455	ascc2	ortholog of human ASCC2%2C part of the TRIP4 complex  that enhances activation of NF-kappa-B%2C SRF%2C and AP1
chr3	3378782	3380059	-	DDB_G0280457	DDB_G0280457	NA
chr3	3381127	3386525	+	DDB_G0280525	DDB_G0280525	NA
chr3	3386881	3391295	+	DDB_G0280459	abcC15	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr3	3391535	3392987	-	DDB_G0280461	DDB_G0280461	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family
chr3	3394025	3396265	-	DDB_G0280463	DDB_G0280463	NA
chr3	3396577	3397708	+	DDB_G0280465	DDB_G0280465	similar to bacterial 3-hydroxybutyryl-CoA dehydrogenase%3B similar to human HADH (3-hydroxyacyl-CoA dehydrogenase)
chr3	3398652	3398986	-	DDB_G0280467	DDB_G0280467	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr3	3399574	3402079	-	DDB_G0280469	psrA	regulatory B56 subunit of protein phosphatase 2A involved in developmental cell fate decision
chr3	3403854	3409622	+	DDB_G0280471	DDB_G0280471	NA
chr3	3412476	3414653	+	DDB_G0280473	hbx9	NA
chr3	3414983	3415636	-	DDB_G0280475	coq7	ortholog of the conserved COQ7%2C a protein which in %3Ci%3ES. cerevisiae%3C%2Fi%3E is required for ubiquinone (coenzyme Q) biosynthesis
chr3	3416378	3425292	+	DDB_G0280527	DDB_G0280527	putative ortholog of TSC2%2C a GTPase activator involved in tuberous sclerosis%3B belongs to the tuberin family 
chr3	3425404	3426876	-	DDB_G0280477	DDB_G0280477	similar to H. sapiens C10orf11 and D. melanogaster MESK4 (MisExpression Suppressor of KSR 4)
chr3	3427999	3428747	-	DDB_G0280479	arrE	NA
chr3	3429343	3431710	-	DDB_G0280481	DDB_G0280481	conserved hypothetical protein
chr3	3432872	3433788	-	DDB_G0280483	fsjA	ortholog of the RrmJ%2FFtsJ ribosomal RNA methyltransferase%2C a well conserved heat shock protein present in prokaryotes%2C archaea%2C and eukaryotes%3B responsible for methylating 23 S rRNA
chr3	3434014	3435699	+	DDB_G0280485	jcdH	NA
chr3	3435776	3436690	-	DDB_G0280487	DDB_G0280487	NA
chr3	3437042	3438999	+	DDB_G0280489	wdr46	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr3	3445379	3448072	+	DDB_G0280491	DDB_G0280491	The RWP-RK domain is named after a conserved motif at its C-terminus%3B found in %3Ci%3EChlamydomonas%3C%2Fi%3E%2C plant proteins involved in nitrogen-controlled development%2C and in %3Ci%3EDictyostelium%3C%2Fi%3E
chr3	3448667	3450469	+	DDB_G0280493	DDB_G0280493	NA
chr3	3450744	3452416	+	DDB_G0280495	fumH	catalyzes the reaction (S)-malate %3C%3D%3E fumarate %2B H%3Csub%3E2%3C%2Fsub%3EO%3B hydrates fumarate into malate in the TCA
chr3	3452686	3453148	+	DDB_G0280497	DDB_G0280497	NA
chr3	3454488	3455138	+	DDB_G0280501	DDB_G0280501	NA
chr3	3455362	3457138	-	DDB_G0280503	DDB_G0280503	NA
chr3	3457915	3459485	+	DDB_G0280505	tmem144A	similar to human TMEM144%3B contains 10 predicted transmembrane domains
chr3	3459592	3460950	-	DDB_G0280507	DDB_G0280507	NA
chr3	3461453	3464060	+	DDB_G0280529	cstf2	component of the CSTF complex%2C which in mammalian  is required for polyadenylation and 3%27-end cleavage of pre-mRNAs
chr3	3464216	3466870	-	DDB_G0280509	DDB_G0280509	NA
chr3	3467320	3471121	+	DDB_G0280511	DDB_G0280511	NA
chr3	3471532	3474399	-	DDB_G0280513	DDB_G0280513	NA
chr3	3477222	3479301	-	DDB_G0280515	DDB_G0280515_ps	putative pseudogene%3B very similar to  %3Ca href%3D%22%2Fgene%2FDDB_G0280757%22%3EDDB_G0280757%3C%2Fa%3E
chr3	3480039	3480317	-	DDB_G0280517	DDB_G0280517	NA
chr3	3481319	3482516	+	DDB_G0280549	DDB_G0280549	NA
chr3	3483317	3484567	+	DDB_G0280551	DDB_G0280551	NA
chr3	3484694	3489068	-	DDB_G0280539	abcC13	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr3	3490523	3495125	+	DDB_G0280555	DDB_G0280555	NA
chr3	3496721	3498209	+	DDB_G0280557	DDB_G0280557	similar to erkA and erkB and other MAP kinases%3B does not contain the consensus sequences required for kinase function
chr3	3499719	3500485	+	DDB_G0280559	DDB_G0280559	similar to many different classes of kinases%2C including several MAPKs%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr3	3500769	3505118	-	DDB_G0280541	abcC1	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr3	3505318	3505698	-	DDB_G0280561	DDB_G0280561	NA
chr3	3506050	3506220	-	DDB_G0280563	DDB_G0280563	NA
chr3	3506773	3509429	-	DDB_G0280565	DDB_G0280565	shares a short region of similarity with beta spectrin at the amino terminus
chr3	3510967	3512917	-	DDB_G0280567	ctps	catalyzes the reaction L-glutamine %2B H%3Csub%3E2%3C%2Fsub%3EO %2B UTP %2B ATP -%3E CTP %2B phosphate %2B ADP %2B L-glutamate in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine ribonucleotides
chr3	3513680	3514010	+	DDB_G0280569	uqcrq	ortholog of mammalian UQCRQ%2C a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is part of the mitochondrial respiratory chain
chr3	3514430	3516337	+	DDB_G0280571	fut8	distant relative of CAZy family GT23%3B catalyzes N-linked glycosylation
chr3	3516876	3517759	+	DDB_G0280573	DDB_G0280573	NA
chr3	3519504	3522563	+	DDB_G0280575	DDB_G0280575	NA
chr3	3522934	3523548	+	DDB_G0280577	DDB_G0280577	NA
chr3	3523763	3524566	-	DDB_G0280579	DDB_G0280579	NA
chr3	3524824	3526893	-	DDB_G0280581	DDB_G0280581	NA
chr3	3528408	3532230	-	DDB_G0280583	DDB_G0280583	NA
chr3	3532604	3533548	+	DDB_G0280585	ubqK	NA
chr3	3534055	3534516	+	DDB_G0280587	ubqK_ps2	NA
chr3	3534995	3535938	+	DDB_G0280589	ubqK_ps1	putative pseudogene%3B ubiquitin family%2C very similar to the upstream %3Ca href%3D%22%2Fgene%2FDDB_G0280585%22%3EubqK%3C%2Fa%3E gene
chr3	3536455	3537354	+	DDB_G0280739	ubqK_ps3	putative pseudogene%3B ubiquitin family%2C very similar to the upstream %3Ca href%3D%22%2Fgene%2FDDB_G0280585%22%3EubqK%3C%2Fa%3E gene
chr3	3537587	3538930	-	DDB_G0280591	DDB_G0280591	NA
chr3	3540460	3543408	+	DDB_G0280593	DDB_G0280593	NA
chr3	3543819	3545699	+	DDB_G0280535	sdhA	catalyzes the reaction succinate %2B ubiquinone %3D fumarate %2B ubiquinol
chr3	3546088	3546563	-	DDB_G0280595	ndufb7	similar to human NDUFB7%2C which is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) 
chr3	3546928	3547282	-	DDB_G0280597	DDB_G0280597	NA
chr3	3548058	3551669	-	DDB_G0280599	fhkB	CAMK group%2C RAD53 family protein kinase%3B the protein kinase domain is similar to those of mammalian cell cycle checkpoint kinases chk2%3B contains a forkhead-associated (FHA) domain%2C a phosphopeptide recognition domain found in many regulatory proteins
chr3	3552325	3557379	-	DDB_G0294585	DDB_G0294585	contains a domain found in the family of Major Royal Jelly Proteins%2C constituting 82-90%25 of the protein in honeybee royal jelly 
chr3	3558531	3558908	+	DDB_G0280601	DDB_G0280601	NA
chr3	3559151	3562381	-	DDB_G0280603	rliD	repressed after %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr3	3563786	3564293	+	DDB_G0280605	DDB_G0280605	NA
chr3	3564619	3565542	+	DDB_G0280607	pfdn5	component of the prefoldin complex responsible for targeting proteins to cytosolic chaperonin CCT
chr3	3565940	3566062	-	DDB_G0280609	ost4	subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of S. cerevisiae OST4%3B contains one transmembrane domain
chr3	3567052	3567876	+	DDB_G0280537	wacA	member of the major intrinsic protein (MIP) family of membrane transporters%3B expressed starting at culmination stage in prespore cells
chr3	3568288	3569667	-	DDB_G0280613	DDB_G0280613	NA
chr3	3570182	3572203	+	DDB_G0280615	DDB_G0280615	NA
chr3	3573818	3574033	+	DDB_G0280617	cyp519C2_ps	putative pseudogene%3B related to the cytochrome P450 family
chr3	3574246	3574318	-	DDB_G0295141	tRNA-Lys-UUU-11	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr3	3575172	3576962	+	DDB_G0280619	DDB_G0280619	NA
chr3	3577717	3578283	+	DDB_G0280621	arrJ	NA
chr3	3578410	3581076	-	DDB_G0280623	tgrC3	NA
chr3	3582758	3583771	-	DDB_G0280627	gtaS	has 20 amino acids between the two CX2C motifs
chr3	3585207	3585534	+	DDB_G0280629	DDB_G0280629_ps	NA
chr3	3586248	3586814	+	DDB_G0280633	arrK	NA
chr3	3587080	3589805	-	DDB_G0280635	tgrC2	NA
chr3	3590686	3591824	+	DDB_G0280637	DDB_G0280637	NA
chr3	3591954	3594115	-	DDB_G0280741	DDB_G0280741	NA
chr3	3594965	3596077	+	DDB_G0280639	gtaT	has 20 amino acids between the two CX2C motifs %3Cbr%2F%3E %3Cbr%2F%3E%3Cb%3ECommunity annotation: %3C%2Fb%3E In a study of %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FrblA%22%3E retinoblastoma%3C%2Fa%3E-regulated gene expression by tag sequencing of cDNA  (Doquang et al.%2C in preparation) gtaT showed the strongest rb-dependence of all  detected genes. A major function of rblA seems to be the control of mitotic and DNA-replication genes%2C  and gtaT may control functions which must be turned off for Dictyostelium cell  cycle progression.  %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FGtaT%22%3E There is more information on the wiki page%3C%2Fa%3E.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr3	3597358	3597498	-	DDB_G0280641	DDB_G0280641	NA
chr3	3598294	3599733	-	DDB_G0280643	DDB_G0280643	similar to many CMGC family members%2C including several MAPKs
chr3	3604056	3604451	+	DDB_G0280547	comH	isolated in a screen for communication mutants%3B similar to %3Ci%3EEmericella nidulans NsdD%3C%2Fi%3E%3B has 20 amino acids between the two CX2C motifs
chr3	3605551	3606033	-	DDB_G0280533	lmcB	vegetative-specific gene repressed at the onset of development
chr3	3606827	3607108	+	DDB_G0349153	hdaC_ps5	putative pseudogene%3B small fragment%2C similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0280195%22%3E%3Ci%3EhdaC%3C%2Fi%3E%3C%2Fa%3E
chr3	3607110	3607270	+	DDB_G0349155	patA_ps	putative pseudogene%3B small fragment%2C similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0277861%22%3E%3Ci%3EpatA%3C%2Fi%3E%3C%2Fa%3E
chr3	3608634	3610770	-	DDB_G0280743	tgrC_ps1	putative pseudogene%3B immunoglobulin E-set family gene
chr3	3611170	3611925	+	DDB_G0280651	tgrB_ps	putative pseudogene%3B immunoglobulin E-set family gene
chr3	3614124	3614606	-	DDB_G0280543	lmcA	vegetative-specific gene repressed at the onset of development
chr3	3616454	3616642	+	DDB_G0280655	DDB_G0280655	NA
chr3	3616982	3617481	-	DDB_G0280659	DDB_G0280659	NA
chr3	3617623	3618225	-	DDB_G0280661	DDB_G0280661	NA
chr3	3618324	3618740	+	DDB_G0280663	DDB_G0280663	NA
chr3	3618907	3619353	+	DDB_G0280665	DDB_G0280665	NA
chr3	3620960	3621457	-	DDB_G0280673	DDB_G0280673	NA
chr3	3621809	3622246	-	DDB_G0280675	DDB_G0280675	NA
chr3	3623268	3623941	+	DDB_G0280677	DDB_G0280677_ps	putative pseudogene%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0280751%22%3EDDB_G0280751%3C%2Fa%3E
chr3	3624484	3624780	-	DDB_G0280679	act37_ps	putative pseudogene%3B contains a partial actin domain
chr3	3626750	3627247	+	DDB_G0280683	arrJ_ps	putative pseudogene%3B ADP-ribosylation factor family protein
chr3	3627702	3629015	-	DDB_G0280685	DDB_G0280685_ps	putative pseudogene%3B very similar to argonaut genes agnA and agnB as well as to portions of midasin (mdn1)%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0280685 is twentyfold overexpressed  in a Dictyostelium strain in which the retinoblastoma-like protein rblA has been disrupted (Doquang et al%2C in preparation). The promoter region of this gene contains an element (GCGCCAAA) which is highly enriched in rblA-repressed promoters. It appears likely that DDB_G0280685 is a highly mutated and no longer makes a functional protein. The mutations in the coding sequence are also present in Nc4b (G. Bloomfield%2C private communication). %3Ci%3EHarry MacWilliams%2C February 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0280685%22%3E There is more information on the wiki page%3C%2Fa%3E
chr3	3629662	3630491	+	DDB_G0280687	arrI_ps	putative pseudogene%3B ADP-ribosylation factor family protein
chr3	3630672	3633406	-	DDB_G0280531	tgrC1	contains a predicted signal peptide%2C IPT%2FTIG domain found in cell surface receptors%2C and a C-terminal transmembrane domain%3B plays a role in aggregation during development%2C in kin discrimination and is highly polymorphic between different isolates of %3Ci%3ED. discoideum%3C%2Fi%3E%3B forms a cell-cell adhesion complex with tgrB1
chr3	3633930	3636846	+	DDB_G0280689	tgrB1	contains a signal peptide%2C IPT%2FTIG domain found in cell surface receptors%2C and a C-terminal transmembrane domain%3B plays a role in kin discrimination and is highly polymorphic between different isolates of %3Ci%3ED. discoideum%3C%2Fi%3E%3B forms a cell-cell adhesion complex with tgrC1
chr3	3638436	3638828	+	DDB_G0280691	DDB_G0280691	contains no functional domains and is not similar to any other protein
chr3	3640963	3642068	+	DDB_G0280693	tgrB2	similar to tgr family proteins%3B contains a predicted signal peptide
chr3	3643332	3643893	+	DDB_G0280697	arrG_ps	putative pseudogene%3B ADP-ribosylation factor family protein
chr3	3644331	3645240	-	DDB_G0280745	tgrC_ps2	putative pseudogene%3B immunoglobulin E-set family gene
chr3	3646107	3647707	+	DDB_G0280699	mdn1_ps1	putative pseudogene%3B fragment%2C similar to midasin%2C gene %3Ca href%3D%22%2Fgene%2FDDB_G0295765%22%3Emdn1%3C%2Fa%3E
chr3	3648372	3648641	+	DDB_G0280703	DDB_G0280703	NA
chr3	3648861	3656137	-	DDB_G0280705	chdB	CHD gene family protein containing a chromodomain%2C a C terminal helicase domain%2C and a DNA-binding domain%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr3	3657513	3658445	-	DDB_G0280747	DDB_G0280747	NA
chr3	3660989	3661646	-	DDB_G0280707	DDB_G0280707	NA
chr3	3662714	3664865	+	DDB_G0280709	DDB_G0280709	NA
chr3	3666726	3669518	-	DDB_G0280711	DDB_G0280711_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDB_G0281141%22%3EDB_G0281141%3C%2Fa%3E
chr3	3670258	3671617	-	DDB_G0280717	DDB_G0280717	member of the AGC kinase group%3B similar to the kinase domains of PKC (protein kinase C) and MAST (microtubule-associated serine%2Fthreonine kinase)
chr3	3674980	3676300	+	DDB_G0280749	act35_ps	putative pseudogene%3B contains a partial actin domain
chr3	3676594	3677598	-	DDB_G0280721	DDB_G0280721	NA
chr3	3679412	3680350	-	DDB_G0280751	DDB_G0280751	NA
chr3	3684122	3685252	+	DDB_G0280545	act7	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)  
chr3	3686392	3686902	-	DDB_G0280723	DDB_G0280723_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0280707%22%3EDDB_G0280707%3C%2Fa%3E 
chr3	3688197	3689226	-	DDB_G0280725	DDB_G0280725	almost identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281115%22%3E%3Ci%3EDDB_G0281115%3C%2Fi%3E%3C%2Fa%3E
chr3	3690296	3691048	+	DDB_G0280727	DDB_G0280727	NA
chr3	3691400	3692400	-	DDB_G0280729	DDB_G0280729_ps	putative pseudogene%3B belongs to the pirin family
chr3	3693324	3694079	+	DDB_G0280733	DDB_G0280733	NA
chr3	3694386	3694643	+	DDB_G0294607	DDB_G0294607_ps	putative pseudogene%3B conserved hypothetical protein
chr3	3695606	3695746	-	DDB_G0294605	DDB_G0294605	conserved hypothetical Dictyostelium protein%3B identical to %3Ca href%3D%22%2Fgene%2FDDB_G0277595%22%3EDDB_G0277595%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0269070%22%3EDDB_G0269070%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274459%22%3EDDB_G0274459%3C%2Fa%3E
chr3	3696501	3696687	+	DDB_G0280735	DDB_G0280735_ps	putative pseudogene%3B predicted translation contains the C-terminal domain of pirin%2C a nuclear protein of unknown function
chr3	3696977	3697729	-	DDB_G0280737	DDB_G0280737_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0280727%22%3EDDB_G0280727%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0281117%22%3EDDB_G0281117%3C%2Fa%3E
chr3	3700406	3702924	+	DDB_G0280757	DDB_G0280757	NA
chr3	3703604	3705383	+	DDB_G0280759	DDB_G0280759	NA
chr3	3705496	3707344	-	DDB_G0280761	DDB_G0280761	belongs to the major facilitator superefamily%3B contains 12 putative transmembrane domains
chr3	3708667	3710631	-	DDB_G0280763	hemA	catalyzes the reaction succinyl-CoA %2B glycine %3D 5-aminolevulinate %2B CoA %2B CO%3Csub%3E2%3C%2Fsub%3E
chr3	3715566	3718006	+	DDB_G0280765	DDB_G0280765	contains three kelch repeats and a RING zinc finger
chr3	3718300	3719568	+	DDB_G0280767	DDB_G0280767	NA
chr3	3719733	3720516	-	DDB_G0280769	DDB_G0280769	NA
chr3	3721618	3722020	-	DDB_G0280771	DDB_G0280771	NA
chr3	3722395	3722781	-	DDB_G0280755	ubqB	highly conserved gene consisting a a fusion product between ubiquitin and the L40 ribosomal protein
chr3	3724009	3726993	+	DDB_G0280773	DDB_G0280773	NA
chr3	3727138	3728652	-	DDB_G0280775	rvb2	similar to S. cerevisiae RVB2%2C a component of chromatin remodeling complexes
chr3	3729649	3735545	+	DDB_G0280777	DDB_G0280777	NA
chr3	3735901	3736821	-	DDB_G0280779	DDB_G0280779	NA
chr3	3737208	3738375	-	DDB_G0280781	DDB_G0280781	NA
chr3	3739979	3740353	+	DDB_G0280783	DDB_G0280783	similar to human C15orf40
chr3	3740763	3743681	-	DDB_G0280785	DDB_G0280785	NA
chr3	3744078	3746888	-	DDB_G0280787	DDB_G0280787	NA
chr3	3747630	3750581	-	DDB_G0280809	DDB_G0280809	NA
chr3	3751748	3754420	-	DDB_G0280811	DDB_G0280811	NA
chr3	3754836	3756238	-	DDB_G0280791	DDB_G0280791_ps	putative pseudogene%3B similar to the family of SAP DNA-binding domain-containing proteins
chr3	3756319	3757251	-	DDB_G0280793	DDB_G0280793	NA
chr3	3757477	3759852	-	DDB_G0280795	DDB_G0280795	NA
chr3	3760317	3764888	-	DDB_G0280797	DDB_G0280797	similar to S. cerevisiae RRP12 (ribosomal RNA-processing protein 12)%3B contains one NUC173 domain and an armadillo repeat region
chr3	3765398	3765613	-	DDB_G0280799	DDB_G0280799	NA
chr3	3766917	3770724	+	DDB_G0280801	DDB_G0280801	NA
chr3	3771010	3774818	-	DDB_G0280813	DDB_G0280813	NA
chr3	3775563	3776632	-	DDB_G0280815	trrA	catalyzes the reaction thioredoxin %2B NADP%2B %3C%3D%3E thioredoxin disulfide %2B NADPH %2B H%2B
chr3	3777864	3779318	+	DDB_G0280803	DDB_G0280803	similar to D. purpureum protein
chr3	3779782	3781110	-	DDB_G0280805	DDB_G0280805	homolog of human and S. cerevisiae KRR1 (KRR-R motif-containing protein)%3B contains one RNA-binding KH domain%3B S. cerevisiae KRR1 is required for 40S ribosome biogenesis
chr3	3781925	3782955	-	DDB_G0280817	DDB_G0280817	NA
chr3	3783056	3783504	-	DDB_G0280957	DDB_G0280957	NA
chr3	3785488	3787288	-	DDB_G0280937	DDB_G0280937_ps	putative pseudogene%3B similar to D. discoideum gene  %3Ca href%3D%22%2Fgene%2FDDB_G0272769%22%3EDDB_G0272769%3C%2Fa%3E
chr3	3787769	3789204	-	DDB_G0280851	DDB_G0280851	similar to human PIPOX%2C which has both sarcosine oxidase and L-pipecolate oxidase activity
chr3	3790224	3791400	+	DDB_G0280853	gtaU	has 20 amino acids between the two CX2C motifs
chr3	3794487	3795739	+	DDB_G0280855	DDB_G0280855	similar to erkA and erkB and other MAP kinases%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr3	3797710	3798189	-	DDB_G0280939	DDB_G0280939	NA
chr3	3799596	3800895	+	DDB_G0280857	DDB_G0280857	NA
chr3	3801882	3802523	+	DDB_G0280859	DDB_G0280859	NA
chr3	3803076	3803599	-	DDB_G0280861	DDB_G0280861_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0283091%22%3EDDB_G0283091%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0291592%22%3EDDB_G0291592%3C%2Fa%3E
chr3	3805307	3806260	+	DDB_G0280863	DDB_G0280863	NA
chr3	3806833	3808264	-	DDB_G0280865	DDB_G0280865	NA
chr3	3808603	3809091	-	DDB_G0280941	DDB_G0280941	NA
chr3	3809804	3814700	+	DDB_G0280867	DDB_G0280867	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr3	3814959	3817323	-	DDB_G0280869	DDB_G0280869	NA
chr3	3818142	3818512	-	DDB_G0280871	DDB_G0280871	underexpressed in gskA-null strain
chr3	3820212	3820578	-	DDB_G0280847	2C	cyclic AMP-regulated gene%3B underexpressed in gskA-null strain
chr3	3822028	3822398	-	DDB_G0280873	DDB_G0280873	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3824495	3824971	-	DDB_G0280875	DDB_G0280875	NA
chr3	3825256	3827473	+	DDB_G0280877	DDB_G0280877	NA
chr3	3827972	3830000	-	DDB_G0280879	DDB_G0280879	similar to D. purpureum protein
chr3	3830874	3831824	-	DDB_G0280881	DDB_G0280881	catalyzes the reaction RX %2B glutathione %3D HX %2B R-S-glutathione
chr3	3832477	3832743	+	DDB_G0280883	act38_ps	putative pseudogene%2C contains a partial actin domain
chr3	3832886	3833098	-	DDB_G0280885	DDB_G0280885	contains one putative transmembrane domain
chr3	3833482	3835332	+	DDB_G0280887	arpD	ortholog of A. thaliana ARP4 and very similar to the mammalian actin-like protein 6A%2C which is involved in transcriptional activation and repression of select genes by chromatin remodelling 
chr3	3835530	3836519	-	DDB_G0280889	DDB_G0280889	NA
chr3	3836784	3838939	-	DDB_G0280891	pigV	NA
chr3	3840063	3841393	+	DDB_G0280893	rbsk	catalyzes the reaction D-ribose %2B ATP %3C%3D%3E D-ribose-5-phosphate %2B ADP
chr3	3841507	3846104	-	DDB_G0280895	DDB_G0280895	has the same domain composition as %3Ci%3EfbxA%3C%2Fi%3E and %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285445%22%3E%3Ci%3EDDB_G0285445%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E: contains an N-terminal START (StAR-related lipid-transfer) lipid binding domain%2C a central F-box domain%2C C-terminal WD40 repeats
chr3	3847722	3849533	+	DDB_G0280897	pgmB	ortholog of PGM2%2C which catalyzes the reaction alpha-D-glucose 1-phosphate %3C%3D%3E alpha-D-glucose 6-phosphate
chr3	3852474	3856792	+	DDB_G0280943	elmoD	NA
chr3	3856978	3859184	-	DDB_G0280849	dicA	NA
chr3	3859774	3860817	+	DDB_G0280903	DDB_G0280903	NA
chr3	3861062	3861547	-	DDB_G0280905	DDB_G0280905	NA
chr3	3862138	3865629	+	DDB_G0280907	xpo4	ortholog of H. sapiens XPO4 involved in protein export from nucleus
chr3	3865707	3866767	-	DDB_G0280909	tal	catalyzes the reaction sedoheptulose 7-phosphate %2B D-glyceraldehyde 3-phosphate %3C%3D%3E D-erythrose 4-phosphate %2B D-fructose 6-phosphate
chr3	3867097	3868776	-	DDB_G0280945	DDB_G0280945	NA
chr3	3870282	3873485	+	DDB_G0280911	DDB_G0280911	NA
chr3	3873660	3875525	-	DDB_G0280913	DDB_G0280913	NA
chr3	3875955	3876025	+	DDB_G0295037	tRNA-Gly-GCC-5	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	3876679	3876749	+	DDB_G0295039	tRNA-Gly-GCC-6	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	3877405	3878011	-	DDB_G0280915	DDB_G0280915	NA
chr3	3879930	3880291	-	DDB_G0280919	DDB_G0280919	similar to D. purpureum protein
chr3	3881788	3885032	+	DDB_G0280921	DDB_G0280921	contains a PX (phox) domain%2C which is found in various proteins involved in intracellular signaling
chr3	3885498	3885562	-	DDB_G0295551	sno14	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr3	3886092	3886599	+	DDB_G0280923	DDB_G0280923	contains one putative ankyrin repeat
chr3	3886790	3888946	-	DDB_G0280947	DDB_G0280947	conserved eukaryotic protein of unknown function
chr3	3889342	3889413	+	DDB_G0295041	tRNA-Glu-UUC-11	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr3	3889710	3890076	-	DDB_G0280925	DDB_G0280925	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3890823	3891195	-	DDB_G0280927	DDB_G0280927	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3892080	3892473	-	DDB_G0280929	DDB_G0280929	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3893288	3893652	-	DDB_G0280931	DDB_G0280931	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3894494	3894883	-	DDB_G0280933	DDB_G0280933	contains a predicted coiled-coil region found in a group of Dictyostelium proteins known to be regulated by cAMP
chr3	3898059	3900113	+	DDB_G0280935	DDB_G0280935	NA
chr3	3900382	3900776	-	DDB_G0280949	DDB_G0280949	contains a predicted coiled-coil region found in a group of Dictyostelium proteins known to be regulated by cAMP
chr3	3901597	3901980	-	DDB_G0280951	DDB_G0280951	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3902909	3903326	-	DDB_G0280953	DDB_G0280953	underexpressed in gskA-null strain
chr3	3904017	3906218	-	DDB_G0280955	DDB_G0280955	GTPase activator for rab8A%3B involved in the regulation of contractile vacuole function during hypoosmotic stress
chr3	3912677	3914050	+	DDB_G0280981	pkgE_ps	putative pseudogene%2C similar to AGC protein kinases of the AKT family
chr3	3914149	3915176	-	DDB_G0280985	udpB	catalyzes the reaction phosphate %2B uridine %3C%3D%3E ribose-1-phosphate %2B uracil in salvage pathways of pyrimidine ribonucleotides and deoxyribose phosphate degradation
chr3	3916236	3917206	+	DDB_G0280987	DDB_G0280987	NA
chr3	3917295	3918133	-	DDB_G0280989	hop2	conserved protein forms a complex with mnd1 and is required for pairing homologous chromosomes during meiosis
chr3	3918547	3920423	-	DDB_G0280991	DDB_G0280991	NA
chr3	3921693	3923045	+	DDB_G0280993	DDB_G0280993	similar to serologically defined breast cancer antigen 84 (sdbcag84%2FERGIC3)%3B putative transmembrane protein that may have a role transport between endoplasmic reticulum and Golgi
chr3	3923506	3926616	+	DDB_G0280995	mps1	putative protein threonine%2Ftyrosine kinase%3B similar to yeast and zebrafish mps1 (monopolar spindle) kinase%2C a threonine%2Ftyrosine kinase
chr3	3926681	3927709	-	DDB_G0280997	DDB_G0280997	NA
chr3	3928566	3928902	+	DDB_G0280999	DDB_G0280999	NA
chr3	3929799	3930159	+	DDB_G0281001	DDB_G0281001	similar to other Dictyostelium small coiled-coil proteins
chr3	3930956	3931315	+	DDB_G0281003	DDB_G0281003	underexpressed in gskA-null strain%3B highly similar to other Dictyostelium small coiled-coil proteins
chr3	3932248	3932628	+	DDB_G0281005	DDB_G0281005	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3933475	3933849	+	DDB_G0281007	DDB_G0281007	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3934450	3934822	+	DDB_G0281009	DDB_G0281009_ps	putative pseudogene%3B hssA%2F2C%2F7E family gene
chr3	3935487	3935880	+	DDB_G0281011	DDB_G0281011	NA
chr3	3936625	3936988	+	DDB_G0281013	DDB_G0281013	contains a predicted coiled-coil region found in a group of Dictyostelium proteins known to be regulated by cAMP%3B highly similar to %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281017%22%3E%3Ci%3EDDB_G0281017%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr3	3937648	3938030	+	DDB_G0281015	DDB_G0281015	NA
chr3	3938819	3939189	+	DDB_G0281017	DDB_G0281017	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3939911	3940261	+	DDB_G0281019	DDB_G0281019	underexpressed in gskA-null strain
chr3	3940485	3940922	-	DDB_G0281021	DDB_G0281021	similar to yeast ERG28%2C an endoplasmic reticulum protein involved in ergosterol biosynthesis 
chr3	3944292	3946934	+	DDB_G0281025	DDB_G0281025	NA
chr3	3947337	3947903	-	DDB_G0281027	DDB_G0281027	NA
chr3	3948101	3950782	+	DDB_G0281029	DDB_G0281029	NA
chr3	3951371	3955510	+	DDB_G0281031	pldA	catalyzes the reaction a phosphatidylcholine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E choline %2B a phosphatidate%3B expressed throughout growth and development
chr3	3956014	3956307	-	DDB_G0281033	DDB_G0281033	NA
chr3	3957131	3958162	+	DDB_G0281035	DDB_G0281035	NA
chr3	3958898	3959659	+	DDB_G0281037	DDB_G0281037	NA
chr3	3959819	3960946	-	DDB_G0281039	DDB_G0281039	NA
chr3	3961441	3961602	-	DDB_G0281041	DDB_G0281041	NA
chr3	3963633	3965636	+	DDB_G0281043	DDB_G0281043	NA
chr3	3967277	3973178	+	DDB_G0281045	DDB_G0281045	similar to Saccharomyces cerevisiae SIN3 gene
chr3	3973435	3975824	-	DDB_G0281047	gxcEE	NA
chr3	3977638	3978912	+	DDB_G0281049	DDB_G0281049	NA
chr3	3979792	3981586	+	DDB_G0281051	psmD12	NA
chr3	3982008	3982871	+	DDB_G0281053	DDB_G0281053	conserved hypothetical Dictyostelium protein%3B similar to bacterial ubiquinone%2Fmenaquinone biosynthesis methyltransferase ubiE
chr3	3983103	3983966	+	DDB_G0281055	DDB_G0281055	conserved hypothetical Dictyostelium protein%3B similar to bacterial ubiquinone%2Fmenaquinone biosynthesis methyltransferase ubiE
chr3	3984594	3986192	+	DDB_G0281057	DDB_G0281057	NA
chr3	3986737	3993698	+	DDB_G0280963	rrpC	RNA-directed RNA polymerase involved in RNA interference and the production of siRNA%3B involved in the metabolism of other miRNAs%2C posttranscriptionally regulates silences the centromeric retrotransposon DIRS1 and spreads the RNA silencing signals both in the 5%27 and 3%27 directions
chr3	3993886	3993958	-	DDB_G0295139	tRNA-Ala-AGC-7	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr3	3994227	3995458	+	DDB_G0281059	DDB_G0281059	NA
chr3	3996913	3997278	+	DDB_G0281295	DDB_G0281295	highly similar to other Dictyostelium small coiled-coil proteins
chr3	3999282	4000753	-	DDB_G0281061	wdr4	similar to H. sapiens WDR4%2C which is required for 7-methylguanosine modification of tRNA and forms a complex with METTL1
chr3	4001320	4001787	+	DDB_G0281065	DDB_G0281065	NA
chr3	4002363	4003396	-	DDB_G0281067	DDB_G0281067	contains a putative signal peptide and a C-terminal transmembrane domain
chr3	4003785	4006768	+	DDB_G0281069	DDB_G0281069	NA
chr3	4007757	4009455	+	DDB_G0281071	serA	catalyzes the reaction 3-phosphoglycerate %2B NAD %3C%3D%3E 3-phospho-hydroxypyruvate %2B NADH
chr3	4009657	4011765	-	DDB_G0281073	DDB_G0281073	NA
chr3	4013016	4014419	-	DDB_G0281075	DDB_G0281075	NA
chr3	4014778	4014850	+	DDB_G0295043	tRNA-Ala-AGC-5	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4014814	4018001	+	DDB_G0281297	DDB_G0281297_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr3	4018746	4019913	-	DDB_G0281299	DDB_G0281299_ps	putative pseudogene%3B similar to the 5%27 half of a small family of genes%2C including%2C %3Ca href%3D%22%2Fgene%2FDDB_G0281077%22%3EDDB_G0281077%3C%2Fa%3E
chr3	4020721	4022888	-	DDB_G0281077	DDB_G0281077	NA
chr3	4024099	4026272	-	DDB_G0281079	DDB_G0281079	NA
chr3	4027472	4029494	+	DDB_G0281081	DDB_G0281081	NA
chr3	4029591	4031531	-	DDB_G0281083	DDB_G0281083	NA
chr3	4032257	4033987	-	DDB_G0281085	tfiiiA	NA
chr3	4034404	4035320	-	DDB_G0281087	gtaV	has 20 amino acids between the two CX2C motifs
chr3	4037372	4038716	-	DDB_G0281089	prkab	non-catalytic subunit of the AMP-activated protein kinase (AMPK) complex
chr3	4039994	4042224	+	DDB_G0281091	DDB_G0281091	contains 3 leucine-rich repeat regions%3B similar to D. purpureum protein
chr3	4042692	4044602	-	DDB_G0280965	gbqA	related to guanine nucleotide-binding protein%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FGbqA%22%3Ecommunity annotation%3C%2Fa%3E
chr3	4045953	4046558	+	DDB_G0281093	rpl37A	protein component of the large (60S) ribosomal subunit
chr3	4046834	4050127	-	DDB_G0281095	DDB_G0281095	NA
chr3	4051226	4054087	-	DDB_G0281301	DDB_G0281301	NA
chr3	4054526	4057419	-	DDB_G0281303	DDB_G0281303_ps	putative pseudogene%3B similar to family of SAP DNA-binding domain-containing proteins in D. discoideum
chr3	4057793	4059529	-	DDB_G0281097	DDB_G0281097	ortholog of the mammalian RNA pseudouridylate synthase domain containing 2 protein (RPUSD2)
chr3	4060002	4061515	+	DDB_G0281099	DDB_G0281099	NA
chr3	4061672	4062828	-	DDB_G0281101	ldhA	ortholog of D-lactate dehydrogenase which converts pyruvate to D-lactate under anareobic conditions
chr3	4064325	4065641	+	DDB_G0281103	gpt10	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr3	4066214	4066923	+	DDB_G0281105	DDB_G0281105	NA
chr3	4067396	4067863	-	DDB_G0281107	DDB_G0281107_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr3	4067961	4068033	+	DDB_G0295045	tRNA-Ala-AGC-6	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4069177	4070741	-	DDB_G0281109	odc	catalyzes the reaction L-ornithine %3D putrescine %2B  CO%3Csub%3E2%3C%2Fsub%3E
chr3	4071325	4073379	-	DDB_G0281111	DDB_G0281111	NA
chr3	4073757	4074677	+	DDB_G0281307	arl2	NA
chr3	4074835	4077522	-	DDB_G0281113	DDB_G0281113	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr3	4078245	4079227	+	DDB_G0281115	DDB_G0281115	almost identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0280725%22%3E%3Ci%3EDDB_G0280725%3C%2Fi%3E%3C%2Fa%3E
chr3	4079565	4080314	-	DDB_G0281117	DDB_G0281117	NA
chr3	4081406	4081981	+	DDB_G0281119	DDB_G0281119_ps	putative pseudogene%3B similar to pirin family proteins%2C especially to parts of DDB_G0281115 and DDB_G0280725
chr3	4082329	4083078	-	DDB_G0281121	DDB_G0281121	NA
chr3	4083976	4084614	+	DDB_G0281123	DDB_G0281123_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0281115%22%3EDDB_G0281115%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0280725%22%3EDDB_G0280725%3C%2Fa%3E
chr3	4085395	4085731	+	DDB_G0281127	DDB_G0281127_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0281133%22%3EDDB_G0281133%3C%2Fa%3E 
chr3	4085896	4086645	-	DDB_G0281131	DDB_G0281131	NA
chr3	4087597	4088060	+	DDB_G0281133	DDB_G0281133	NA
chr3	4088225	4088974	-	DDB_G0281135	DDB_G0281135	NA
chr3	4090199	4090294	-	DDB_G0295137	tRNA-Ala-UGC-6	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4091325	4093522	+	DDB_G0281137	DDB_G0281137	NA
chr3	4093647	4094606	-	DDB_G0281139	DDB_G0281139	NA
chr3	4094898	4098451	-	DDB_G0281141	DDB_G0281141	NA
chr3	4098849	4099499	-	DDB_G0281143	DDB_G0281143	NA
chr3	4100184	4100399	-	DDB_G0281145	DDB_G0281145	NA
chr3	4100955	4101399	-	DDB_G0281147	DDB_G0281147	NA
chr3	4101872	4102553	-	DDB_G0281149	DDB_G0281149	NA
chr3	4103245	4106511	-	DDB_G0281151	DDB_G0281151	weakly similar to Aspergillus fumigatus posttranscriptional regulation nuclease Mkt1
chr3	4106976	4108033	+	DDB_G0281153	eif3H	EIF3H ortholog%2C the eukaryotic initiation factor gamma subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr3	4109358	4113107	+	DDB_G0280967	kif3	kinesin-1 family protein%2C involved in intracellular transport%3B belongs to the kinesin KHC subfamily
chr3	4113808	4115562	+	DDB_G0281155	DDB_G0281155	putative sugar transporter%3B contains 12 putative transmembrane domains
chr3	4116092	4117309	+	DDB_G0281157	DDB_G0281157	NA
chr3	4117529	4120886	+	DDB_G0281159	DDB_G0281159	NA
chr3	4120970	4121650	-	DDB_G0281309	DDB_G0281309	conserved in plants and fungi
chr3	4122141	4122650	-	DDB_G0281311	DDB_G0281311	NA
chr3	4123947	4124664	-	DDB_G0281161	DDB_G0281161	NA
chr3	4125474	4128500	+	DDB_G0281163	cog2	highly similar to COG2%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits
chr3	4129870	4132265	+	DDB_G0281165	DDB_G0281165	similar to Lycopersicon peruvianum HSF24 (SwissProt P22335)
chr3	4132807	4145996	+	DDB_G0281167	dnapkcs	atypical%2C PIKK family protein kinase%3B similar to human DNA-PKcs%2C required for the repair of DNA double-strand breaks%3B belongs to the PIKK family of protein kinases
chr3	4146807	4147062	+	DDB_G0281169	DDB_G0281169	NA
chr3	4147505	4148552	-	DDB_G0280969	psmA4	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr3	4148918	4150249	-	DDB_G0281171	oxaB	similar to OXA1%2C a conserved inner mitochondrial membrane protein that is required for the activity and assembly of cytochrome oxidase and for the insertion of integral membrane proteins into the mitochondrial inner membrane%3B there is a second putative oxidase assembly protein in %3Ci%3ED. discoideum%3Ci%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284883%22%3E%3Ci%3EoxaA%3C%2Fi%3E%3C%2Fa%3E
chr3	4150932	4152746	+	DDB_G0281313	DDB_G0281313	NA
chr3	4153223	4155157	+	DDB_G0281315	psmD11	contains tetratricopeptide-like helical binding domain
chr3	4155822	4157663	+	DDB_G0281317	DDB_G0281317	NA
chr3	4157794	4158635	-	DDB_G0349057	DDB_G0349057	NA
chr3	4159819	4160163	+	DDB_G0281173	DDB_G0281173	NA
chr3	4160503	4163008	-	DDB_G0281319	DDB_G0281319	NA
chr3	4163655	4165436	+	DDB_G0281175	trmt6	ortholog of the human TRM6 and yeast GCD10%2C which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA as a heterodimer with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0271512%22%3E%3Ci%3Etrmt61%3C%2Fi%3E%3C%2Fa%3E
chr3	4165613	4166323	-	DDB_G0281177	tmem208	conserved protein
chr3	4167312	4170856	+	DDB_G0281179	clkA	similar to cyclin-like kinases (CLK)%2C putative dual specifity kinase
chr3	4171126	4172256	-	DDB_G0281181	DDB_G0281181	NA
chr3	4173081	4174808	+	DDB_G0281183	DDB_G0281183	similar to topoisomerase 1-binding RING finger proteins%2C has similarity to the mammalian ubiquitin-protein E3 ligase TOPORS (topoisomerase I-binding arginine%2Fserine-rich protein)
chr3	4176225	4177722	+	DDB_G0281185	DDB_G0281185	NA
chr3	4178520	4179137	+	DDB_G0281321	DDB_G0281321	NA
chr3	4179327	4180254	-	DDB_G0281187	DDB_G0281187	conserved hypothetical 278 aa Dictyostelium protein
chr3	4180654	4180940	-	DDB_G0281189	DDB_G0281189	related to the hssA genes
chr3	4181682	4181955	+	DDB_G0281191	DDB_G0281191	NA
chr3	4182117	4183047	-	DDB_G0281193	DDB_G0281193	conserved hypothetical 278 aa Dictyostelium protein
chr3	4183476	4183732	-	DDB_G0281195	DDB_G0281195	related to the hssA genes
chr3	4184500	4184768	+	DDB_G0281197	DDB_G0281197	NA
chr3	4184950	4185867	-	DDB_G0281199	DDB_G0281199	conserved hypothetical 278 aa Dictyostelium protein%3B centrosomal component
chr3	4186363	4187263	+	DDB_G0281201	DDB_G0281201	conserved hypothetical 278 aa Dictyostelium protein%3B centrosomal component
chr3	4187406	4189973	-	DDB_G0281323	DDB_G0281323	NA
chr3	4191095	4192891	+	DDB_G0281325	DDB_G0281325	similar to prtein in D. purpureum an in the see anemone N. vectensis%3B contains an N-terminal signal sequence and a C-terminal transmembrane domain
chr3	4193116	4194082	+	DDB_G0281327	rexo4	similar to H. sapiens REXO4 and S. cerevisiae REX4
chr3	4194528	4194623	+	DDB_G0295047	tRNA-Ala-UGC-4	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4194901	4199620	-	DDB_G0281203	DDB_G0281203_ps	putative pseudogene%3B very similar to the large neighboring gene %3Ca href%3D%22%2Fgene%2FDDB_G0281207%22%3EDDB_G0281207%3C%2Fa%3E
chr3	4199950	4204779	-	DDB_G0281207	DDB_G0281207	contains a predicted signal peptide and a C-terminal transmembrane domain%3B conserved in Dictyostelium and Polysphondylium
chr3	4207203	4209040	+	DDB_G0281209	DDB_G0281209	NA
chr3	4210774	4213017	+	DDB_G0281211	grlL	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr3	4213401	4217074	-	DDB_G0280959	DG1113	NA
chr3	4220018	4226569	+	DDB_G0280961	dhkA	two-component histidine kinase%2C which first autophosphorylates a histidine%2C and then transfers the phosphate onto an aspartate before the signal is transduced%3B also known as histidyl-aspartyl phosphorelay
chr3	4226854	4228465	-	DDB_G0281213	pex3	ortholog of peroxin 3%2C required for peroxisome biogenesis%3B contains two transmembrane domains%3B mutations in human homolog cause a variety of peroxisomal disorders
chr3	4228761	4230881	-	DDB_G0281215	brf1	general transcription factor required for the initiation of transcription by RNA polymerase III%3B TFIIIB subunit%2C interacts with the non LTR retrotransposon TRE5-A
chr3	4231408	4233727	+	DDB_G0281217	DDB_G0281217	NA
chr3	4234799	4235929	-	DDB_G0281219	DDB_G0281219	NA
chr3	4236950	4238575	+	DDB_G0281221	tbccd	NA
chr3	4239018	4240493	+	DDB_G0281223	DDB_G0281223	NA
chr3	4240788	4240858	+	DDB_G0295049	tRNA-Gly-UCC-1	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	4242261	4243821	-	DDB_G0281225	DDB_G0281225	NA
chr3	4244319	4244805	+	DDB_G0281227	DDB_G0281227	NA
chr3	4245222	4246856	+	DDB_G0281229	pnkp	similar to PNKP%2C an enzyme with dual polynucleotide kinase and 3%27-phosphatase activities%2C involved in DNA repair
chr3	4247160	4247230	-	DDB_G0295135	tRNA-Gly-UCC-5	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	4247788	4252597	+	DDB_G0281231	DDB_G0281231	NA
chr3	4253054	4253503	+	DDB_G0281233	DDB_G0281233	NA
chr3	4253816	4255131	-	DDB_G0280983	crlA	involved in negative regulation of growth%3B belongs to the serpentine%2FG-protein coupled receptor family
chr3	4255795	4257140	-	DDB_G0281235	DDB_G0281235	NA
chr3	4257593	4260812	+	DDB_G0281237	DDB_G0281237	contains an N-terminal F-box domain and a putative ankyrin repeat region
chr3	4261304	4262400	+	DDB_G0281239	impa1	catalyzes the reaction myo-inositol phosphate %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E myo-inositol %2B phosphate%3B human IMPA1 is a pharmacological target for Li%2B in the treatment of manic depression
chr3	4263598	4265076	+	DDB_G0281241	coq2	catalyzes the reaction solanesyl diphosphate %2B 4-hydroxybenzoate %3C%3D%3E diphosphate %2B nonaprenyl-4-hydroxybenzoate in ubiquinone biosynthesis
chr3	4265275	4266052	-	DDB_G0281243	DDB_G0281243	NA
chr3	4266691	4266763	+	DDB_G0295051	tRNA-Lys-CUU-5	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4268093	4268165	-	DDB_G0295133	tRNA-Lys-UUU-10	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4268319	4268999	+	DDB_G0281245	DDB_G0281245_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr3	4269757	4269936	-	DDB_G0281247	DDB_G0281247_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr3	4270315	4270387	-	DDB_G0295131	tRNA-Lys-UUU-9	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4270661	4272089	+	DDB_G0281329	DDB_G0281329_ps	putative pseudogene%3B fragment%3B similar to D. discoideum FNIP repeat-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0282515%22%3EDDB_G0282515%3C%2Fa%3E 
chr3	4272791	4277032	-	DDB_G0281249	DDB_G0281249	NA
chr3	4278355	4280707	+	DDB_G0281331	DDB_G0281331	putative protein serine%2Fthreonine kinase%3B similar to vertebrate Nek kinases which are involved in regulation of mitosis%3B contains 7 predicted transmembrane domains
chr3	4282030	4286706	+	DDB_G0281251	DDB_G0281251	NA
chr3	4286715	4294937	+	DDB_G0280971	lvsC	similar to human LYST and mouse Beige proteins
chr3	4295825	4296729	+	DDB_G0281253	rsmB	NA
chr3	4297271	4297366	-	DDB_G0295129	tRNA-Ala-UGC-5	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4298212	4301618	+	DDB_G0281255	sec24	component of COPII (coat protein complex II) involved in ER to Golgi transport
chr3	4301960	4305349	+	DDB_G0281257	DDB_G0281257	NA
chr3	4305745	4307064	+	DDB_G0281259	DDB_G0281259	similar to the DREV (DORA reverse strand) protein found in other eukaryotes%3B believed to be a methyltransferase but is of unknown function
chr3	4307171	4310514	-	DDB_G0281261	DDB_G0281261	similar to human G-patch-containing 1 protein (GPATC1)
chr3	4310870	4311391	+	DDB_G0281263	DDB_G0281263	contains no functional domains
chr3	4311777	4313915	-	DDB_G0281265	DDB_G0281265	NA
chr3	4314924	4316454	+	DDB_G0281269	DDB_G0281269	NA
chr3	4316503	4317240	-	DDB_G0281271	DDB_G0281271	NA
chr3	4317752	4318070	-	DDB_G0281273	DDB_G0281273	NA
chr3	4318553	4321252	-	DDB_G0281333	DDB_G0281333	NA
chr3	4322092	4322352	-	DDB_G0281275	DDB_G0281275	NA
chr3	4322929	4331907	-	DDB_G0281277	med12	putative ortholog of the mediator of RNA polymerase II transcription subunit 12%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr3	4333375	4335700	+	DDB_G0281279	DDB_G0281279	NA
chr3	4335971	4336735	-	DDB_G0281281	DDB_G0281281	NA
chr3	4337681	4338432	+	DDB_G0281283	DDB_G0281283	NA
chr3	4338670	4339580	-	DDB_G0281285	DDB_G0281285	NA
chr3	4340141	4344573	-	DDB_G0280973	abcC12	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr3	4345792	4346996	+	DDB_G0281287	DDB_G0281287	NA
chr3	4347748	4352153	+	DDB_G0280977	abcC10	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr3	4352682	4352741	-	DDB_G0295553	r33	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr3	4353450	4353523	-	DDB_G0295127	tRNA-Phe-GAA-10	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4354163	4355462	-	DDB_G0280975	racE	interacts with gxcT%2C rgaA and darA%3B acts together with fttB (14-3-3) to regulate the cortical cytoskeleton and cleavage furrow progression during cytokinesis
chr3	4356442	4357481	+	DDB_G0280979	pcmA	similar to PIMT or PCMT (L-isoaspartyl%2FD-aspartyl protein carboxyl methyltransferase or protein-L-isoaspartate (D-aspartate) O-methyltransferase)
chr3	4358553	4360353	+	DDB_G0281289	DDB_G0281289	NA
chr3	4360504	4361689	-	DDB_G0281291	DDB_G0281291	putative ortholog of the transcription cofactor 30 kDa HIV-1 Tat interactive protein 2 (HTATIP2)
chr3	4362245	4363103	-	DDB_G0281293	ddiA	NA
chr3	4368638	4369552	+	DDB_G0281339	DDB_G0281339	NA
chr3	4370112	4370426	+	DDB_G0281341	DDB_G0281341	NA
chr3	4370772	4372312	-	DDB_G0281369	DDB_G0281369	NA
chr3	4372875	4374176	-	DDB_G0281371	DDB_G0281371	NA
chr3	4376038	4378565	+	DDB_G0281343	shkD	member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily%3B contains a C-terminal SH2 (Src homology 2) domain
chr3	4379229	4379825	+	DDB_G0281345	DDB_G0281345	NA
chr3	4380507	4382346	+	DDB_G0281349	DDB_G0281349_ps	fragment%2C very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0272765%22%3E DDB_G0272765 %3C%2Fa%3E
chr3	4383385	4384571	-	DDB_G0281337	rab14	similar to M. musculus rab14
chr3	4385822	4387835	-	DDB_G0281351	trappc12	conserved trafficking protein particle (TRAPP) complex subunit%3B
chr3	4388160	4394973	+	DDB_G0281353	DDB_G0281353	NA
chr3	4395483	4396600	-	DDB_G0281355	DDB_G0281355_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr3	4397502	4399358	-	DDB_G0281357	DDB_G0281357_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr3	4400356	4400426	-	DDB_G0295125	tRNA-Gly-GCC-9	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	4401226	4402349	+	DDB_G0281359	DDB_G0281359	NA
chr3	4403294	4405281	+	DDB_G0281361	DDB_G0281361	NA
chr3	4405679	4408201	+	DDB_G0281377	DDB_G0281377	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D
chr3	4409131	4409210	+	DDB_G0295555	sno9	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr3	4409414	4409477	+	DDB_G0294409	sno1	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr3	4410114	4413041	+	DDB_G0281363	DDB_G0281363	putative ortholog of H. sapiens CNOT10%3B contains several putative TPR repeats
chr3	4413139	4413285	-	DDB_G0281365	DDB_G0281365	NA
chr3	4413344	4413414	+	DDB_G0295053	tRNA-Gly-GCC-7	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	4413764	4414489	-	DDB_G0281367	DDB_G0281367	NA
chr3	4415599	4417045	+	DDB_G0281379	DDB_G0281379	NA
chr3	4417290	4419659	-	DDB_G0295713	DDB_G0295713	NA
chr3	4421049	4422099	+	DDB_G0281393	cxdA	NA
chr3	4422701	4423114	-	DDB_G0281395	DDB_G0281395	NA
chr3	4424611	4426259	-	DDB_G0281399	DDB_G0281399	NA
chr3	4429232	4433391	+	DDB_G0281401	DDB_G0281401	contains 10 transmembrane domains
chr3	4433625	4434218	+	DDB_G0281403	nacA	highly similar to the alpha subunit of the nascent polypeptide-associated complex (NAC)%2C which binds the nascent polypeptide after peptide bond formation
chr3	4435413	4438134	+	DDB_G0281407	tgrC5	NA
chr3	4439811	4440920	+	DDB_G0281409	drpp25	protein subunit of both the RNase P complex involved in tRNA processing and the RNase MRP complex involved in rRNA processing
chr3	4442749	4443108	+	DDB_G0281413	DDB_G0281413	NA
chr3	4443494	4446173	+	DDB_G0281415	DDB_G0281415	NA
chr3	4448074	4450633	+	DDB_G0281381	dstA	NA
chr3	4451020	4452035	-	DDB_G0281417	DDB_G0281417	unknown protein%2C contains 4 predicted transmembrane domains
chr3	4452796	4457645	-	DDB_G0281419	ncapGa	putative component of the condensin I complex%2C required for conversion of interphase chromatin into mitotic condensed chromosomes%3B There is another putative NCAPG gene in D. discoideum (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275129%22%3E%3Ci%3EncapGb%3C%2Fi%3E%3C%2Fa%3E)%3B two genes are also present in D. purpureum
chr3	4458032	4458114	+	DDB_G0295055	tRNA-Leu-UAA-7	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4458420	4461368	+	DDB_G0281421	DDB_G0281421	NA
chr3	4461687	4464665	+	DDB_G0281423	DDB_G0281423	NA
chr3	4464773	4467683	-	DDB_G0281519	lin54	putative ortholog of human tesmin (MTL5) and C. elegans lin-54%2C that may play a role in chromatin remodeling or transcriptional repression%3B has two copies of a cysteine rich motif as follows: C-X-C-X4-C-X3-YC-X-C-X6-C-X3-C-X-C-X2-C%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation: %3C%2Fb%3E Lin-54 was originally discovered in worms as a %22synthetic multivulva B gene%22 which partipates in generating a signal from hypodermal cells that represses vulva formation by the vulva precursors. The synthetic multivulva B group also includes the worm retinoblastoma homologue%2C as well as several other genes whose products are known to interact with retinoblastoma in other systems. Newer studies in insects and mammals suggest that the %22synmuv%22 gene products form several multiprotein complexes involved in mediating or moderating the effects of Rb on gene expression %3Ca target %3D%22new%22 href%3D%22http:%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F17671431%22%3E(Schmit et al 2007)%3C%2Fa%3E. Not all of the members of these complexes can be found in Dictyostelium. Unpublished results suggest%2C however%2C that those which can be found are upregulated in cells carrying a disrupted Dictyostelium retinoblastoma gene (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E ). Other strongly regulated putative members of such a complex include  %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2Flin9%22%3Elin9%3C%2Fa%3E%2C  %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2Ftfdp2%22%3Etfdp2%3C%2Fa%3E%2C and  %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FrbbD%22%3ErbbD%3C%2Fa%3E. %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Flin54%22%3E There is more information on the wiki page%3C%2Fa%3E.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E
chr3	4468486	4470184	-	DDB_G0281425	DDB_G0281425	NA
chr3	4470521	4474783	-	DDB_G0281427	DDB_G0281427	NA
chr3	4475058	4476479	+	DDB_G0281429	DDB_G0281429	NA
chr3	4477171	4480036	+	DDB_G0281431	DDB_G0281431	NA
chr3	4480305	4485819	-	DDB_G0281521	DDB_G0281521	member of the bromo-AAA%2BATPase (BRAT) class of chromatin assembly proteins
chr3	4486206	4487897	-	DDB_G0281523	DDB_G0281523	NA
chr3	4494019	4495275	+	DDB_G0281387	srfA	transcription factor expressed in prespore cells%3B required for expression of several genes involved terminal spore differentiation
chr3	4495953	4497167	+	DDB_G0281433	DDB_G0281433	NA
chr3	4497695	4498243	+	DDB_G0281435	mrpl17	protein component of the mitochondrial large ribosomal subunit
chr3	4498697	4500739	-	DDB_G0281437	lysS	catalyzes the reaction ATP %2B L-lysine %2B tRNALys %3D AMP %2B diphosphate %2B L-lysyl-tRNALys
chr3	4501721	4501950	+	DDB_G0281439	DDB_G0281439	NA
chr3	4502255	4507222	-	DDB_G0281441	ercc6	ortholog of %3Ci%3ES. cerevisiae%3C%2Fi%3E RAD26 and  %3Ci%3EH. sapiens%3C%2Fi%3E ERCC6 (CSB)%2C involved in Cockayne syndrome%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr3	4509300	4511664	+	DDB_G0281443	DDB_G0281443	belongs to the fatty acid hydroxylase superfamily%3B contains 8 putative transmembrane domains
chr3	4511889	4511971	-	DDB_G0295123	tRNA-Leu-UAA-10	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4513064	4515098	+	DDB_G0281445	fam63B	NA
chr3	4516135	4517301	+	DDB_G0281447	DDB_G0281447	NA
chr3	4519070	4520084	+	DDB_G0281385	rasC	Ras protein required for aggregation%3B  activated by rasGEF GefA%3B enriched in prestalk cells%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Gene expression is greatly perturbed in vegetative rasC-%2FrasG- double null mutants%2C and in early development a subset of important signalling genes are not induced adequately. Notable among these early genes are acaA%2C dagA%2C erkA%2C erkB%2C gpaB%2C and csbA. The discoidin I genes are also underexpresed. The expression of most of these genes (not the discoidins) is rescued when carA is overexpressed in the double null line.  Most remarkably%2C the overall profile of gene expression changes in vegetative double null mutants compared to the parent strain is highly similar to that of wild-type cells six hours after infection with Legionella pneumophila compared to uninfected cells (in terms of gene expression changes%3B correlation coefficient %3D 0.61) (Li et al%2C 2009)%2C making this strain phenocopy the Legionella-resistant dupA mutant to some extent (correlation coefficient %3D 0.49). Of 55 genes overexpressed at least 4-fold in the vegetative rasC-%2FrasG- double mutant%2C 53 are at least 2-fold induced six hours after Legionella infection in wild-type AX4 cells (including tirA)%3B 37 of these 55 are overexpressed in uninfected dupA mutants. Further%2C 44 of the 55 overexpressed genes are developmentally induced in parental cells%2C and 22 of the 55 show significantly reduced expression upon carA overexpression in vegetative cells. %3Ci%3EGareth Bloomfield%2C November 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FrasC%22%3E There is more information%2C including spatial expression data%2C on the wiki page%3C%2Fa%3E
chr3	4520387	4522336	+	DDB_G0281527	DDB_G0281527	NA
chr3	4522479	4523700	-	DDB_G0281449	DDB_G0281449_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr3	4523794	4523875	+	DDB_G0295057	tRNA-Leu-AAG-2	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4525070	4525402	+	DDB_G0281451	DDB_G0281451_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr3	4525480	4525941	+	DDB_G0281453	DDB_G0281453_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr3	4526091	4529384	+	DDB_G0281455	DDB_G0281455_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr3	4529784	4531056	+	DDB_G0281529	DDB_G0281529_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr3	4532369	4537117	+	DDB_G0281531	DDB_G0281531_ps	putative pseudogene%3B similar to EGF domain-containing proteins like %3Ca href%3D%22%2Fgene%2FDDB_G0270718%22%3EDDB_G0270718%3C%2Fa%3E
chr3	4537876	4538331	+	DDB_G0281461	sodF	superoxide dismutase of the SOD1 family
chr3	4539251	4540424	+	DDB_G0281463	DDB_G0281463	NA
chr3	4540912	4543611	-	DDB_G0281383	glpV	CAZy family GT35%3B 5%27-AMP-dependent glycogen phosphorylase expressed in early development%3B the combined activities of glpV and glpD results in constant glycogen phosphorylase activity throughout development 
chr3	4545446	4546801	+	DDB_G0281465	DDB_G0281465	NA
chr3	4547456	4548845	+	DDB_G0281467	DDB_G0281467	NA
chr3	4548958	4549339	-	DDB_G0281469	rpl29	protein component of the large (60S) ribosomal subunit
chr3	4550105	4552335	-	DDB_G0281471	pdkA	member of the AGC kinase group%3B similar to mammalian PDK (phosphoinositide-dependent protein kinase) known to phosphorylate Akt%2FPKB
chr3	4553203	4555374	+	DDB_G0281473	DDB_G0281473	NA
chr3	4556537	4565616	+	DDB_G0281475	pks18	putative type I iterative polyketide synthase
chr3	4565971	4566041	-	DDB_G0295121	tRNA-Gly-GCC-8	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	4567934	4568006	-	DDB_G0295119	tRNA-Arg-UCU-9	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4571394	4572542	+	DDB_G0281533	DDB_G0281533_RTE	ORF1 encoding GAG and protease (PRO) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr3	4572825	4576826	+	DDB_G0281535	DDB_G0281535_RTE	long terminal repeat -retrotransposon Skipper GAG-PRO-POL%3B refer to GenBank AF049230 for full length consensus element
chr3	4578097	4578735	+	DDB_G0281479	DDB_G0281479_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr3	4579212	4580831	-	DDB_G0281481	DDB_G0281481	NA
chr3	4581015	4583017	-	DDB_G0281537	DDB_G0281537	NA
chr3	4583388	4586436	-	DDB_G0281483	ppr1	regulatory subunit 1 of the protein serine%2Fthreonine phosphatase 4%2C PPC4 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0272116%22%3E%3Ci%3Eppp4C%3C%2Fi%3E%3C%2Fa%3E)
chr3	4586992	4591754	-	DDB_G0281391	abcG5	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr3	4592822	4597860	-	DDB_G0281389	abcG6	full transporter%2C consisting of two ABC domains and two transmembrane domains%3B expressed in prespore cells
chr3	4599041	4603561	+	DDB_G0281485	DDB_G0281485	NA
chr3	4603817	4604947	+	DDB_G0281487	DDB_G0281487	ortholog of the human NSDHL protein and the yeast ERG26 protein%3B belongs to the 3beta-HSD family
chr3	4605058	4605743	-	DDB_G0281489	DDB_G0281489	homolog of human TMCO1 (transmembrane and coiled-coil domain-containing protein 1)%3B contains 2 putative transmembrane domains%3B contains a putative coiled-coil region
chr3	4606291	4606373	+	DDB_G0295059	tRNA-Leu-UAA-8	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4606867	4607943	+	DDB_G0281539	DDB_G0281539_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	4608468	4611647	+	DDB_G0281491	DDB_G0281491_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr3	4612258	4612782	-	DDB_G0281493	sodD	superoxide dismutase of the SOD1 family
chr3	4613433	4613515	-	DDB_G0295117	tRNA-Leu-UAA-9	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4613870	4615132	+	DDB_G0281495	DDB_G0281495	NA
chr3	4615481	4617145	-	DDB_G0281497	DDB_G0281497	NA
chr3	4621318	4626772	+	DDB_G0281499	vinB	has weak similarity to vinculins involved in the attachment of the actin cytoskeleton to the plasma membrane through interactions with talin and alpha-actinin
chr3	4627625	4629265	-	DDB_G0281541	DDB_G0281541	NA
chr3	4629488	4633507	-	DDB_G0281543	DDB_G0281543	NA
chr3	4634453	4636939	+	DDB_G0281501	DDB_G0281501	contains 2 putative transmembrane domains%3B has weak similarity to the N-terminal domain of cytochrome b561
chr3	4637514	4640951	+	DDB_G0281503	DDB_G0281503	NA
chr3	4641293	4642444	-	DDB_G0281505	DDB_G0281505	NA
chr3	4643635	4646580	+	DDB_G0281507	colC	NA
chr3	4647716	4648014	+	DDB_G0281509	DDB_G0281509	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon 
chr3	4648103	4651602	-	DDB_G0281511	cog3	highly similar to COG3%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits
chr3	4652073	4653629	-	DDB_G0281513	DDB_G0281513	similar to solute carrier family 29 (SLC29)
chr3	4654406	4656214	-	DDB_G0281515	DDB_G0281515	similar to solute carrier family 29 (SLC29)
chr3	4657789	4658469	+	DDB_G0281575	DDB_G0281575	NA
chr3	4658517	4659686	+	DDB_G0281577	DDB_G0281577	NA
chr3	4660155	4660226	-	DDB_G0295115	tRNA-Met-CAU-12	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr3	4660486	4661604	+	DDB_G0281579	DDB_G0281579_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	4662931	4663827	+	DDB_G0281581	hsp_ps	putative pseudogene%3B similar to a gene family in Dictyostelium%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0269144%22%3EhspB%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0273249%22%3EhspE-1%3C%2Fa%3E
chr3	4664590	4664956	+	DDB_G0281583	DDB_G0281583	NA
chr3	4665204	4670752	-	DDB_G0281585	cpsf1	ortholog of the human CPSF1 and yeast YTH1%2C the 160 kDa subunit of the cleavage and polyadenylation specificity factor (CPSF) complex required for 3%27 processing of mRNAs%3B human CPSF1 involved in the RNA recognition step of the polyadenylation reaction
chr3	4671220	4673075	-	DDB_G0281547	amyA	similar to A. oryzae alpha-amylase 3 precursor
chr3	4674842	4676185	+	DDB_G0281587	yipf1	very similar to Yip1 domain family%2C member 1 (YIPF1)%3B in S. cerevisiae%2C YIPF1 localizes to the Golgi and interacts with GTPases%3B contains five putative transmembrane domains
chr3	4676319	4677638	-	DDB_G0281589	DDB_G0281589	very similar to mammalian CBWD1 and CBWD2%2C ubiquitiously expressed COBW domain-containing proteins%3B prokaryotic CobW involved in cobalamin (vitamin B12) biosynthesis
chr3	4677792	4683134	-	DDB_G0281571	comE	similar to CigB and COBW
chr3	4683631	4683916	+	DDB_G0281591	colA_ps4	putative pseudogene%3B very small fragment similar to the large colossin A gene %3Ca href%3D%22%2Fgene%2FDDB_G0279833%22%3EcolA%3C%2Fa%3E
chr3	4685430	4686634	+	DDB_G0281595	rchy	NA
chr3	4686750	4687178	-	DDB_G0281795	nacB	NA
chr3	4689130	4690767	+	DDB_G0281797	bkdC	multimeric enzyme (24-mer) transfers 2-methylpropanoyl%2C 3-methylbutanoyl%2C or S-2-methylbutanoyl groups to coenzyme A%3B E2 component of branched-chain keto acid dehydrogenase
chr3	4693112	4693231	+	DDB_G0281597	DDB_G0281597	similar to a D. purpureum protein
chr3	4693676	4696009	-	DDB_G0281799	abkB	atypical protein serine%2Fthreonine kinase%2C contains ABC1 kinase (protein kinase-like) domain%3B yeast ABC1 essential for the electron transfer in the BC(1) complex%3B E.coli homolog required for ubiquinone biosynthesis
chr3	4696808	4697785	+	DDB_G0281599	ccdc130	conserved protein of unknown function
chr3	4697870	4698426	-	DDB_G0281601	DDB_G0281601	NA
chr3	4698687	4700710	+	DDB_G0281603	DDB_G0281603	NA
chr3	4701100	4702904	-	DDB_G0281605	cfaD	autocrine secreted factor that slows cell proliferation acting as a chalone%3B generates two products%2C a 65 kDa and a 27 kDa peptide%3B involved also in cytokinesis and sporulation%3B is required for AprA%27s chalone and chemorepellent activity
chr3	4703616	4704607	-	DDB_G0281607	DDB_G0281607	NA
chr3	4706235	4707167	+	DDB_G0281609	DDB_G0281609	NA
chr3	4707985	4708341	+	DDB_G0281611	DDB_G0281611	NA
chr3	4709076	4711232	+	DDB_G0281551	guaA	catalyzes the reaction xanthosine-5-phosphate %2B H%3Csub%3E2%3C%2Fsub%3EO %2B L-glutamine %2B ATP %3C%3D%3E L-glutamate %2B GMP %2B pyrophosphate %2B AMP in GMP biosynthesis
chr3	4711308	4712233	-	DDB_G0281613	DDB_G0281613	conserved hypothetical 278 aa Dictyostelium protein%3B centrosomal component
chr3	4712751	4713032	-	DDB_G0281615	DDB_G0281615	NA
chr3	4713358	4714263	-	DDB_G0281617	DDB_G0281617	conserved hypothetical 278 aa Dictyostelium protein
chr3	4714928	4716442	+	DDB_G0281619	DDB_G0281619	NA
chr3	4716452	4718620	-	DDB_G0281621	DDB_G0281621	ortholog of the human SART1%2C identified in the spliceosome C complex%3B also similar to yeast SNU66%2C which plays a role in mRNA splicing
chr3	4719332	4723605	-	DDB_G0281623	upf2	up-frameshift suppressor 2 homolog
chr3	4723898	4724440	-	DDB_G0281625	DDB_G0281625	conserved hypothetical protein present in bacteria%2C nematodes%2C plants%2C and fungi
chr3	4725130	4727134	+	DDB_G0281627	DDB_G0281627	NA
chr3	4727952	4728540	+	DDB_G0281629	DDB_G0281629_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0281637%22%3EDDB_G0281637%3C%2Fa%3E 
chr3	4729446	4732858	+	DDB_G0281631	DDB_G0281631_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0281803%22%3EDDB_G0281803%3C%2Fa%3E
chr3	4733270	4736920	+	DDB_G0281803	sma	plays a role in cell migration and cell-cell adhesion
chr3	4737151	4738121	-	DDB_G0281805	DDB_G0281805	NA
chr3	4738827	4739152	+	DDB_G0281633	DDB_G0281633_ps	putative pseudogene%3B fragment%2C similar to pirin family proteins%2C especially to the C-terminal half of DDB_G0281115 and DDB_G0280725
chr3	4739504	4740253	-	DDB_G0281635	DDB_G0281635	NA
chr3	4741312	4741626	+	DDB_G0281807	DDB_G0281807_ps	putative pseudogene%3B fragment%2C similar to pirin family protein
chr3	4742882	4745746	+	DDB_G0281637	DDB_G0281637	NA
chr3	4746209	4748719	+	DDB_G0281639	DDB_G0281639	similar to the guanylate-binding proteins (GBPs) involved in the interferon-induced immune response
chr3	4748825	4750464	-	DDB_G0281641	polD2	the small 50 kD protein might have DNA polymerase delta regulatory function
chr3	4751182	4753968	+	DDB_G0281643	DDB_G0281643	NA
chr3	4754331	4756005	-	DDB_G0281645	DDB_G0281645	NA
chr3	4756428	4757101	-	DDB_G0281647	DDB_G0281647	putative pseudogene%3B fragment%2C similar to the neighboring gene %3Ca href%3D%22%2Fgene%2FDDB_G0281645%22%3EDDB_G0281645%3C%2Fa%3E
chr3	4757942	4760392	+	DDB_G0281649	mkcE	kinase domain similar to those of Dictyostelium mkcA and mkcB%2C and other mitogen-activated protein kinases (Ste20%2FPAK family)
chr3	4760769	4762128	+	DDB_G0281651	ppme1	similar to H. sapiens PPME1%2C which demethylates proteins that have been reversibly carboxymethylated
chr3	4766011	4767857	+	DDB_G0281563	mybC	contains three Myb DNA-binding domains near the C-terminus
chr3	4768142	4769409	-	DDB_G0281653	DDB_G0281653	NA
chr3	4769979	4770495	+	DDB_G0281655	DDB_G0281655	NA
chr3	4770616	4773886	-	DDB_G0281657	DDB_G0281657	NA
chr3	4774706	4775113	+	DDB_G0281659	aplQ	NA
chr3	4777368	4781526	+	DDB_G0281557	drkD	member of the TKL (tyrosine kinase-like) group and the DRK (Dictyostelium receptor-like kinase) subfamily%3B contains a leucine-rich repeat (LRR) region
chr3	4784467	4786077	+	DDB_G0281661	gtaI	has 18 amino acids between the two CX2C motifs 
chr3	4787137	4789219	+	DDB_G0281663	aprA	secreted protein that exists in a 150 kDa complex%3B repressor of cell proliferation and exhibits chemorepellant activity
chr3	4789355	4790776	-	DDB_G0281665	DDB_G0281665	NA
chr3	4791599	4794060	+	DDB_G0281669	lmbd2B	transmembrane protein%3B associated with endocytic cups and plays a role in cell migration
chr3	4794386	4798555	-	DDB_G0281671	DDB_G0281671	NA
chr3	4799865	4800848	+	DDB_G0281673	DDB_G0281673	NA
chr3	4800986	4801423	-	DDB_G0281675	DDB_G0281675	NA
chr3	4801949	4802463	-	DDB_G0281677	rps26	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S26 homolog
chr3	4804047	4805222	+	DDB_G0281679	DDB_G0281679	NA
chr3	4806161	4810447	+	DDB_G0281683	msh3	NA
chr3	4810538	4812581	-	DDB_G0281685	nol1	possible RNA methyltransferase%3B ortholog of H. sapiens NOL1 and S. cerevisiae NOP2
chr3	4813506	4816440	+	DDB_G0281687	DDB_G0281687	ortholog of the human U2-associated protein SR140 a putative regulator of pre-mRNA splicing
chr3	4816615	4817211	-	DDB_G0281689	DDB_G0281689	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281691%22%3E%3Ci%3EDDB_G0281691%3C%2Fi%3E%3C%2Fa%3E
chr3	4817955	4818596	+	DDB_G0281691	DDB_G0281691	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281689%22%3E%3Ci%3EDDB_G0281689%3C%2Fi%3E%3C%2Fa%3E
chr3	4819674	4823774	+	DDB_G0281555	kif7	NA
chr3	4825161	4825826	+	DDB_G0281565	rpl19	protein component of the large (60S) ribosomal subunit
chr3	4826796	4831443	-	DDB_G0281573	gefP	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr3	4833441	4834541	+	DDB_G0281693	trappc6	conserved trafficking protein particle (TRAPP) complex subunit%3B higher similarity to human TRAPP6B than to TRAPP6A
chr3	4835697	4836672	+	DDB_G0302418	imp4	ortholog of the conserved eukaryotic IMP4%3B component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) required for pre-18S rRNA processing%3B forms a heterotrimeric complex containing IMP3 and MPP10
chr3	4836494	4838094	-	DDB_G0281695	DDB_G0281695	NA
chr3	4838618	4838997	-	DDB_G0281697	DDB_G0281697	NA
chr3	4840109	4844968	-	DDB_G0281809	DDB_G0281809	conserved protein containing a Rap%2Fran-GAP (GTPase activating protein) domain
chr3	4845968	4848415	-	DDB_G0281561	tipA	involved in early development and tip formation%3B the protein phosphatase 2C-related domain occurs in protein phosphatase 2C (PPC2) as well as in other proteins%2C such as pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase
chr3	4849870	4851348	+	DDB_G0281699	DDB_G0281699	NA
chr3	4851537	4851880	-	DDB_G0281701	DDB_G0281701	NA
chr3	4852577	4852987	+	DDB_G0281703	nedd8l1	very similar to the conserved NEDD8 (neddylin) protein%2C however%2C the C-terminus is extended and lacks the conserved cleavage site
chr3	4853137	4854186	-	DDB_G0281705	DDB_G0281705	NA
chr3	4855046	4856017	-	DDB_G0281707	DDB_G0281707	contains a putative transmembrane domain at the C terminus
chr3	4856414	4857069	-	DDB_G0295825	mrpl34	protein component of the mitochondrial large ribosomal subunit
chr3	4857991	4858413	-	DDB_G0281811	DDB_G0281811	NA
chr3	4859387	4861954	-	DDB_G0281813	DDB_G0281813	NA
chr3	4862322	4866125	+	DDB_G0281709	DDB_G0281709	NA
chr3	4866495	4869027	+	DDB_G0281711	ddx27	ortholog of H. sapiens DDX27 and S. cerevisiae DRS1 (Deficiency of Ribosomal Subunits 1)
chr3	4869216	4869587	-	DDB_G0281713	DDB_G0281713	NA
chr3	4870020	4870371	-	DDB_G0281715	smlA_ps1	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0287587%22%3E%3Ci%3EsmlA%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0282815%22%3EDDB_G0282815%3C%2Fa%3E
chr3	4870585	4871074	+	DDB_G0281717	smlA_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0287587%22%3E%3Ci%3EsmlA%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0282815%22%3EDDB_G0282815%3C%2Fa%3E
chr3	4871788	4873878	+	DDB_G0281567	fhkC	CAMK group%2C RAD53 family protein kinase%3B similar to mammalian cell cycle checkpoint kinases chk2 and yeast RAD53%3B contains a forkhead-associated (FHA) domain%2C a phosphopeptide recognition domain found in many regulatory proteins
chr3	4874420	4877744	-	DDB_G0281719	DDB_G0281719	NA
chr3	4880176	4881555	-	DDB_G0281723	DDB_G0281723	contains an N-terminal actin-binding WH2 (Wiskott Aldrich syndrome homology region 2) domain
chr3	4883727	4884819	+	DDB_G0281725	ube2m	accepts NEDD8 from the UBE1C-APPBP1 E1 complex and catalyzes its covalent attachment to other proteins (second step in NEDD8 conjugation)
chr3	4885508	4886302	-	DDB_G0281727	DDB_G0281727	NA
chr3	4886865	4888149	-	DDB_G0281729	DDB_G0281729	NA
chr3	4889095	4892360	+	DDB_G0281733	DDB_G0281733	NA
chr3	4892895	4894703	-	DDB_G0281735	DDB_G0281735	contains 9 transmembrane domains as predicted by TMHMM2.0%3B enriched in gametes
chr3	4897459	4898536	-	DDB_G0281737	DDB_G0281737	NA
chr3	4898948	4901276	-	DDB_G0281739	gacY	NA
chr3	4903167	4904990	+	DDB_G0281741	cct3	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr3	4905122	4909573	-	DDB_G0281743	DDB_G0281743	NA
chr3	4910382	4912175	+	DDB_G0281745	DDB_G0281745	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family
chr3	4912687	4913451	+	DDB_G0281747	DDB_G0281747	conserved protein family similar to S. cerevisiae OPI10 (OverProducer of Inositol)%2C possibly involved in phospholipid biosynthesis
chr3	4913622	4914745	-	DDB_G0281815	DDB_G0281815	NA
chr3	4915108	4916323	+	DDB_G0281749	DDB_G0281749	NA
chr3	4916395	4917360	-	DDB_G0281751	DDB_G0281751	NA
chr3	4920824	4921042	+	DDB_G0281753	DDB_G0281753	NA
chr3	4923705	4923908	+	DDB_G0281757	DDB_G0281757	NA
chr3	4924793	4925983	-	DDB_G0281759	DDB_G0281759	NA
chr3	4926150	4927037	-	DDB_G0281761	DDB_G0281761	NA
chr3	4927454	4928627	-	DDB_G0281763	DDB_G0281763	RNA-binding protein%3B similar to human SSB  (Sjoegren Syndrome type B antigen) that plays a role in the transcription of RNA polymerase III%2C and yeast LHP1 protein%2C a molecular chaperone which is required for maturation of tRNA and snRNA precursors
chr3	4929179	4929300	+	DDB_G0295557	rnu4b	component of the spliceosome involved in pre-mRNA splicing
chr3	4929751	4929873	-	DDB_G0295559	rnu4a	component of the spliceosome involved in pre-mRNA splicing
chr3	4930354	4933471	+	DDB_G0281767	DDB_G0281767	NA
chr3	4934294	4934544	+	DDB_G0281769	DDB_G0281769	NA
chr3	4934791	4942180	-	DDB_G0281569	tor	atypical%2C PIKK family%2C FRAP subfamily protein kinase%3B ortholog of tor%2C a protein kinase that plays a central role in response to nutrients%2C stress and intracellular energy state%3B called mTOR in mammals in dTOR in Drosophila%3B  %09component of the TORC2 (Tor complex 2) with Rip3%2C Lst8%2C and PiaA that  plays a role in regulation of adenylate cyclase (ACA) and protein kinase B (PKB) activation during aggregation %3Cbr%2F%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with torA%2C encoding tortoise%2C required for chemotaxis
chr3	4943706	4944176	+	DDB_G0281771	DDB_G0281771	contains a predicted signal peptide%3B similar to D. purpureum protein
chr3	4945906	4947427	-	DDB_G0281773	mon1	ortholog of MON1 homologs in animals and MON1 in yeast%2C which functions in vacuolar fusion of autophagosomes and cvt-vesicles
chr3	4948067	4949528	+	DDB_G0281775	DDB_G0281775	NA
chr3	4949807	4951339	+	DDB_G0281553	helC	NA
chr3	4951421	4952644	-	DDB_G0281777	DDB_G0281777	NA
chr3	4953475	4954320	+	DDB_G0281779	lsm2	member of heteromeric complexes involved in mRNA splicing (lsm2-8) and mRNA degradation (lsm1-7)
chr3	4958602	4963128	+	DDB_G0281545	acaA	twelve transmembrane domain adenylyl cyclase expressed during aggregation%3B essential for streaming in early development
chr3	4963446	4965153	-	DDB_G0281817	DDB_G0281817	NA
chr3	4965873	4967936	-	DDB_G0281781	DDB_G0281781	NA
chr3	4968465	4970967	-	DDB_G0281783	DDB_G0281783	NA
chr3	4971939	4974761	-	DDB_G0281785	DDB_G0281785	NA
chr3	4975775	4976524	-	DDB_G0281819	DDB_G0281819	conserved in amoeba and alveolates
chr3	4977091	4978539	-	DDB_G0281549	coxA	ortholog of COX15%2C required for the hydroxylation of heme O to form heme A%2C a component of cytochrome c oxidase
chr3	4978870	4981935	-	DDB_G0281559	DDB_G0281559	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog%3B REMI mutant forms large sori%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0281559%22%3Ecommunity annotation%3C%2Fa%3E
chr3	4982225	4983345	+	DDB_G0281787	gpn2	conserved protein
chr3	4983430	4984948	-	DDB_G0281789	DDB_G0281789	NA
chr3	4985633	4986452	+	DDB_G0281793	DDB_G0281793	NA
chr3	4990977	4993121	+	DDB_G0281829	gtaJ	has 18 amino acids between the two CX2C motifs
chr3	4993575	4994081	-	DDB_G0281831	DDB_G0281831	conserved in bacteria%3B a member of the NK (nucleoside%2Fnucleotide kinase) superfamily%3B also belongs to the zeta toxin family%2C which in bacteria is a component of a postregulational killing system
chr3	4994441	4995199	-	DDB_G0281833	DDB_G0281833	NA
chr3	4995492	4996860	+	DDB_G0281835	DDB_G0281835	NA
chr3	4996941	4997559	-	DDB_G0281837	DDB_G0281837	conserved in eukaryotes
chr3	4997894	5000502	+	DDB_G0281839	DDB_G0281839	ortholog of H. sapiens BOP1 and S. cerevisiae ERB1 involved in maturation of the 25S and 5.8S rRNAs
chr3	5000989	5003811	+	DDB_G0281841	ddx24	ortholog of H. sapiens DDX24 and S. cerevisiae MAK5 (MAintenance of Killer 5)
chr3	5003890	5005484	-	DDB_G0281843	DDB_G0281843	similar to D. purpureum protein%3B also contains two EGF repeats
chr3	5006578	5010931	+	DDB_G0281845	DDB_G0281845	NA
chr3	5011508	5011826	+	DDB_G0281847	DDB_G0281847	NA
chr3	5012149	5014049	+	DDB_G0281849	cct5	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr3	5014229	5016793	-	DDB_G0281851	DDB_G0281851	NA
chr3	5017017	5022329	-	DDB_G0281853	iliL	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D%3B contains a predicted signal peptide%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr3	5023432	5025642	-	DDB_G0281823	v4-7	NA
chr3	5029047	5030143	-	DDB_G0281821	eloB	NA
chr3	5030913	5035144	-	DDB_G0281857	DDB_G0281857	NA
chr3	5036440	5037036	+	DDB_G0281859	bloc1s5	similar to human MUTED and mouse Muted%2C which is involved in the development of lysosome-related organelles%3B contains one putative coiled-coil domain 
chr3	5037215	5037808	+	DDB_G0281937	DDB_G0281937	highly similar to plant proteins of unknown function
chr3	5038245	5040197	+	DDB_G0281861	DDB_G0281861	NA
chr3	5040353	5042502	-	DDB_G0281863	slob1	similar to D. melanogaster Slob (Slowpoke binding protein) and mammalian Pxk (PX domain-containing kinase)%3B does not contain the consensus sequences required for kinase function%2C however%2C the Slob family encodes highly conserved non-canonical kinases that are believed to function
chr3	5043162	5044640	-	DDB_G0281865	adh5	ortholog of H. sapiens ADH5 and other mammalian ADHs %3B zinc-containing dimeric enzyme responsible for the oxidation of long-chain alcohols and omega-hydroxy fatty acids
chr3	5045020	5045250	-	DDB_G0281867	DDB_G0281867	NA
chr3	5047304	5050507	+	DDB_G0281939	DDB_G0281939	NA
chr3	5050887	5051127	-	DDB_G0281869	DDB_G0281869	NA
chr3	5051942	5054758	+	DDB_G0281871	DDB_G0281871	NA
chr3	5055049	5055612	-	DDB_G0281873	pfdn4	component of the prefoldin complex responsible for targeting proteins to cytosolic chaperonin CCT
chr3	5056031	5056821	+	DDB_G0281875	DDB_G0281875	NA
chr3	5057597	5059840	+	DDB_G0281877	nhe2	NA
chr3	5060032	5060301	-	DDB_G0281879	DDB_G0281879	NA
chr3	5062706	5064053	-	DDB_G0281883	DDB_G0281883	NA
chr3	5065537	5068680	-	DDB_G0281941	DDB_G0281941_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5068971	5070305	-	DDB_G0281943	DDB_G0281943_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5070744	5070829	+	DDB_G0295061	tRNA-Thr-CGU-1	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5071587	5072946	+	DDB_G0281945	DDB_G0281945	NA
chr3	5073921	5074207	+	DDB_G0281887	DDB_G0281887	NA
chr3	5074777	5076633	+	DDB_G0281889	tubA2	%3Cb%3ECommunity annotation%3C%2Fb%3E: As most other species%2C Dicty has two alpha-tubulin genes%2C and  only one of each beta- and gamma-tubulin. Dicty%27s two alpha tubulin genes are both moderately upregulated in the Dicty rblA disruptant%2C but tubA2 is substantially more so.  In development%2C tubA2 shows an expression trajectory approximating that of mitotic genes%2C while tubA does not. The promoter of tubA2 contains a likely E2F binding sequence (ATTGGCGCT). It is possible%2C but perhaps not compelling%2C that tubA2 has specific mitotic functions.   %3Ci%3EHarry MacWilliams%2C July 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FtubA2%22%3E There is more information on the wiki page%3C%2Fa%3E
chr3	5076786	5080139	-	DDB_G0281891	rbg3	NA
chr3	5083659	5086073	+	DDB_G0281895	mrkC	CAMKL family protein kinase%2C similar to MARK kinases%2C SNF1 kinases%2C and AMPK kinases%3B contains C-terminal kinase associated domain 1
chr3	5087099	5087704	+	DDB_G0281897	DDB_G0281897	NA
chr3	5088116	5090879	-	DDB_G0281899	drkC	tyrosine kinase%3B member of the TKL (tyrosine kinase-like) group and the DRK (Dictyostelium receptor-like kinase) subfamily%3B involved in phagocytosis and late phagosome%2Flysosome fusion%3B enriched in S cells in slugs
chr3	5091808	5093614	-	DDB_G0281901	slu7	conserved splicing factor participating in the second catalytic step of splicing
chr3	5094433	5095945	+	DDB_G0281903	DDB_G0281903	NA
chr3	5096179	5098987	+	DDB_G0281905	DDB_G0281905	NA
chr3	5099224	5103373	+	DDB_G0281907	DDB_G0281907	weakly similar to human ATPase family AAA domain-containing protein 5 (ATAD5) that is involved in DNA damage response%2C and to yeast ELG1 (Enhanced Level of Genomic instability)%2C which is required for S phase progression%2C telomere homeostasis%2C and homologous recombination-mediated DNA repair%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0281907 is weakly similar to elg1%2C a protein related to rfc1%2C which together with rfc2-5 participates in the loading and perhaps unloading of the %22sliding clamp%22 PCNA%2C a scaffold that recruits proteins involved in DNA replication and repair.%3Cbr%3E DDB_G0281907 is ninefold overexpressed (p%3C2e-27) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). Most genes with roles in cell cycle progression are overexpressed in this strain%2C and most overexpressed genes have identifiable roles in cell cycle progression. It thus seems likely that DDB_G0281907 plays a role in Dictyostelium cell cycle progression. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0281907%22%3E There is more information on the wiki page%3C%2Fa%3E
chr3	5103620	5105863	-	DDB_G0281909	DDB_G0281909	NA
chr3	5106919	5108104	+	DDB_G0281911	DDB_G0281911	6-transmembrane domain-containing protein conserved in Dictyostelids and similar to a protein in ciliates
chr3	5108423	5109952	-	DDB_G0281913	DDB_G0281913	conserved in plants%2C fungi and bacteria
chr3	5110614	5111690	-	DDB_G0281915	DDB_G0281915	unknown protein%2C contains 4 predicted transmembrane domains
chr3	5112758	5119385	-	DDB_G0281825	comB	NA
chr3	5121103	5122056	+	DDB_G0281917	DDB_G0281917	NA
chr3	5122667	5124147	+	DDB_G0281919	DDB_G0281919	NA
chr3	5124821	5125936	+	DDB_G0281921	DDB_G0281921	member of the ZIP (Zrt- and Irt-like Protein) family capable of transporting zinc and other metal ions%3B contains 6 transmembrane domains
chr3	5126146	5126218	-	DDB_G0295113	tRNA-Arg-UCU-8	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5126418	5131891	-	DDB_G0281923	mrhA	very conserved in Dictyosteliids%3B contains a motif related to the HAP2-GCS1 domain
chr3	5132437	5134280	-	DDB_G0281925	DDB_G0281925	similar to ddx5 and ddx17
chr3	5135547	5137365	+	DDB_G0281827	dwwA	homologous to human KIBRA protein%2C a Dendrin binding protein
chr3	5137846	5151854	+	DDB_G0281947	tra1	atypical protein kinase%2C belongs to the PIKK family of protein kinases%3B similar to transformation%2Ftranscription domain-associated protein (TRRAP)
chr3	5152552	5153667	+	DDB_G0281927	DDB_G0281927	NA
chr3	5153973	5156042	-	DDB_G0281929	DDB_G0281929	NA
chr3	5156500	5160486	-	DDB_G0281931	DDB_G0281931	NA
chr3	5161271	5163028	-	DDB_G0281933	nola4	ortholog of human DKC1 (DysKeratosis Congenita 1) and yeast CBF5 (Centromere Binding Factor 5)%3B component of the H%2FACA small nucleolar ribonucleoprotein (H%2FACA snoRNP) complex required for pre-mRNA processing and pseudouridylation
chr3	5163572	5165530	-	DDB_G0281935	DDB_G0281935	NA
chr3	5166543	5170692	+	DDB_G0281955	agnD	NA
chr3	5171485	5172095	+	DDB_G0281959	agnF	NA
chr3	5172400	5172787	+	DDB_G0281961	DDB_G0281961	contains a putative penicillin binding domain used in bacterial resistance mechanisms
chr3	5173395	5174956	+	DDB_G0281963	DDB_G0281963	NA
chr3	5175300	5175752	+	DDB_G0281965	DDB_G0281965	NA
chr3	5176361	5180936	+	DDB_G0282069	slrA	enriched expression in Sentinel cells in the slug%3B contains plant-specific leucine-rich repeats
chr3	5181089	5183302	-	DDB_G0281967	DDB_G0281967	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D
chr3	5184689	5184787	+	DDB_G0295769	DDB_G0295769	NA
chr3	5185447	5185545	+	DDB_G0295767	DDB_G0295767	NA
chr3	5185590	5186037	-	DDB_G0282071	DDB_G0282071	NA
chr3	5190182	5192638	+	DDB_G0281969	mybE	contains one Myb DNA-binding domain
chr3	5193203	5193814	-	DDB_G0281953	DDB_G0281953	NA
chr3	5194623	5197502	+	DDB_G0281957	ap1g1	associates with other subunits to form a bona fide AP-1 complex (clathrin adaptor complex 1)
chr3	5200691	5201407	+	DDB_G0281971	DDB_G0281971	NA
chr3	5202408	5203061	+	DDB_G0281973	DDB_G0281973	NA
chr3	5203577	5204248	-	DDB_G0281975	DDB_G0281975	NA
chr3	5205115	5207257	+	DDB_G0282073	gxcG	NA
chr3	5207662	5207832	-	DDB_G0281977	DDB_G0281977	NA
chr3	5208875	5210138	-	DDB_G0281979	DDB_G0281979	NA
chr3	5210687	5212544	-	DDB_G0281951	cyrA	contains three slime mold repeats%2C and 4 EGF-like domains%3B extracellular similar to prestalk protein precursor%3B protein cleaved into a 45 and 40 kDa fragments found in the slime sheath%3B interacts extracellularly with calmodulin%3B the cyrA EGFL1 peptide regulates chemotactic cell motility%3B TalB and PaxB are required for DdEGFL1 to enhance cell motility
chr3	5213481	5214734	+	DDB_G0281981	DDB_G0281981	NA
chr3	5214975	5215799	-	DDB_G0281983	tmem50	conserved hypothetical protein%3B contains a signal peptide and three transmembrane domains
chr3	5216752	5219266	+	DDB_G0281985	sec23	component of COPII (coat protein complex II) involved in ER to Golgi transport
chr3	5219597	5220032	-	DDB_G0281987	lyrm1	belongs to a family of short proteins that includes ndufa6 from the NADH-ubiquinone oxidoreductase complex I%3B named LYR after a highly conserved tripeptide motif
chr3	5221448	5221843	+	DDB_G0281989	ponM	structurally similar to ponticulins
chr3	5222837	5224029	+	DDB_G0281991	nse4	NA
chr3	5224852	5225898	+	DDB_G0281993	DDB_G0281993	NA
chr3	5226169	5226351	-	DDB_G0281995	DDB_G0281995	NA
chr3	5227597	5227892	-	DDB_G0281997	DDB_G0281997	NA
chr3	5230177	5230887	+	DDB_G0281999	DDB_G0281999	NA
chr3	5231139	5234051	+	DDB_G0282001	DDB_G0282001	NA
chr3	5234145	5234268	-	DDB_G0282003	hat_ps	putative pseudogene%3B small fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0282143%22%3E%3Ci%3EhatB%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0292136%22%3E%3Ci%3EhatC%3C%2Fi%3E%3C%2Fa%3E
chr3	5234911	5235930	+	DDB_G0282005	DDB_G0282005	similar to the mammalian lysophospholipase LYPLA2
chr3	5236311	5237319	+	DDB_G0282007	uch1	catalyzes the thiol-dependent hydrolysis of ester%2C thiolester%2C amide%2C peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin%3B most closely related to human UCHL1 aned UCHL3
chr3	5237565	5238371	-	DDB_G0282009	ahhA	highly similar to mammalian adducin 1%3B expressed in pstO cells and in pstAB%2C pstO%2C and stalk cells during culmination%3B underexpressed in dstA- cells
chr3	5239385	5240941	-	DDB_G0282075	xpnpep3	probable Xaa-Pro aminopeptidase 3%2C that releases any N-terminal amino acid%2C including proline%2C that is linked to proline%2C even from a dipeptide or tripeptide
chr3	5241503	5243356	+	DDB_G0282011	DDB_G0282011	very similar to the mammalian CDC91L1 and yeast GAB1 (CDC91)%2C a proteinGPI transamidase subunit%2C involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins
chr3	5243942	5244486	+	DDB_G0282013	DDB_G0282013	NA
chr3	5245292	5245462	+	DDB_G0282015	DDB_G0282015	NA
chr3	5245886	5247937	+	DDB_G0282017	DDB_G0282017	involved in vesicle-mediated transport%3B similar to VPS33 
chr3	5248124	5249332	-	DDB_G0282019	DDB_G0282019	NA
chr3	5249750	5250385	-	DDB_G0282021	DDB_G0282021	conserved in Polysphondylium pallidum
chr3	5253354	5255651	-	DDB_G0282025	DDB_G0282025	NA
chr3	5256784	5257884	+	DDB_G0282077	DDB_G0282077	NA
chr3	5258026	5266453	-	DDB_G0282027	pks19	putative type I iterative polyketide synthase
chr3	5268803	5277315	-	DDB_G0282079	pks20_ps	putative pseudogene%3B polyketide synthase family protein
chr3	5278421	5280345	+	DDB_G0282083	DDB_G0282083_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr3	5280749	5280979	+	DDB_G0282085	DDB_G0282085_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr3	5285533	5294049	-	DDB_G0282029	pks21	putative type I iterative polyketide synthase
chr3	5295248	5296587	+	DDB_G0282033	DDB_G0282033	very similar to major vault proteins%2C however%2C much smaller including %3Ci%3ED. discoideum%3C%2Fi%3E mvpA and mvpB%2C which are double the length
chr3	5297220	5298359	+	DDB_G0282087	DDB_G0282087	NA
chr3	5298628	5299779	-	DDB_G0282035	eif2s2	EIF2S2 ortholog%2C the eukaryotic initiation factor 2 beta subunit%3B in human%2C binds to the 40S ribosome and to the mRNA for form a preinitiation complex%3B complex composed of 3 subunits
chr3	5300180	5302549	+	DDB_G0295715	DDB_G0295715	ortholog of H. sapiens NSUN2 and S. cerevisiae NCL1
chr3	5303301	5309508	+	DDB_G0282089	DDB_G0282089_ps	similar to other uncharacterized Dictyostelium proteins
chr3	5309986	5314608	-	DDB_G0281949	helE	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr3	5314939	5317726	-	DDB_G0282093	DDB_G0282093	NA
chr3	5318807	5319082	+	DDB_G0282037	DDB_G0282037	NA
chr3	5319634	5319904	+	DDB_G0282039	DDB_G0282039	NA
chr3	5320048	5321192	-	DDB_G0282041	DDB_G0282041	NA
chr3	5321663	5321734	+	DDB_G0295063	tRNA-Glu-CUC-1	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr3	5325920	5325990	-	DDB_G0295111	tRNA-Gly-UCC-4	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	5326311	5328458	-	DDB_G0282045	vps36	component of the ELL complex%2C an RNA polymerase II transcription factor%2C and of the ESCRT-II complex (endosomal sorting complex required for transport)
chr3	5328852	5330706	+	DDB_G0282047	bzpM	NA
chr3	5331009	5333054	+	DDB_G0282049	bzpK	NA
chr3	5333581	5333661	-	DDB_G0295109	tRNA-Ser-GCU-9	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5335122	5335202	-	DDB_G0295107	tRNA-Ser-GCU-8	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5335654	5336709	+	DDB_G0282051	DDB_G0282051_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5339366	5339446	-	DDB_G0295105	tRNA-Ser-GCU-7	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5339807	5341565	-	DDB_G0282055	DDB_G0282055	NA
chr3	5342487	5347862	+	DDB_G0282057	DDB_G0282057	NA
chr3	5349087	5350668	+	DDB_G0295849	DDB_G0295849	NA
chr3	5351024	5353834	+	DDB_G0282095	DDB_G0282095	NA
chr3	5353948	5357409	-	DDB_G0282059	DDB_G0282059	NA
chr3	5358457	5359449	-	DDB_G0282061	DDB_G0282061	NA
chr3	5360341	5362074	-	DDB_G0282063	DDB_G0282063	similar to D. purpureum protein
chr3	5362723	5363052	+	DDB_G0282065	DDB_G0282065	NA
chr3	5363274	5364995	-	DDB_G0282067	DDB_G0282067	belongs to a family of zinc transporters that are integral membrane proteins%2C which are found to increase tolerance to divalent metal ions%3B contains 6 putative transmembrane domains
chr3	5366397	5368196	+	DDB_G0282099	rio2	atypical%2C RIO family protein kinase%3B contains winged helix DNA-binding domain in addition to RIO domain%3B yeast serine%2Fthreonine kinase RIO1 plays a role in cell cycle progression
chr3	5368452	5368825	-	DDB_G0282097	cxfA	NA
chr3	5369694	5372796	+	DDB_G0282101	DDB_G0282101	NA
chr3	5372934	5376503	-	DDB_G0282103	abcG24	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr3	5377643	5380519	+	DDB_G0282105	DDB_G0282105	protein phosphatase 2C is a serine%2Fthreonine specific protein phosphatase with broad substrate specificity and dependent on divalent cations (mainly manganese and magnesium) for its activity
chr3	5381150	5383925	+	DDB_G0282131	DDB_G0282131	contains a predicted signal sequence and a putative C-terminal transmembrane domain%3B similar to D. purpureum protein
chr3	5384175	5384618	-	DDB_G0282107	DDB_G0282107	similar to Aspergillus oryzae phosphatidylglycerol%2Fphosphatidylinositol transfer protein%3B expressed in pstO cells during culmination
chr3	5385033	5385461	-	DDB_G0282109	DDB_G0282109	contains one ML (MD-2-related lipid recognition) domain%3B similar to fungal proteins of the NPC2 family%3B contains a predicted signal peptide
chr3	5385904	5388939	-	DDB_G0282111	DDB_G0282111	NA
chr3	5389429	5398078	-	DDB_G0282133	DDB_G0282133	NA
chr3	5398887	5399607	+	DDB_G0282113	DDB_G0282113	NA
chr3	5399711	5404710	-	DDB_G0282115	DDB_G0282115	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr3	5405787	5407437	+	DDB_G0282135	DDB_G0282135	conserved hyphothetical protein%3B similar to AprA%2C an autocrine repressor of proliferation
chr3	5408423	5409244	-	DDB_G0282117	DDB_G0282117	NA
chr3	5409867	5412620	+	DDB_G0349203	DDB_G0349203	NA
chr3	5413178	5418634	+	DDB_G0349205	DDB_G0349205	NA
chr3	5419274	5420731	+	DDB_G0282121	DDB_G0282121	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr3	5421032	5422501	-	DDB_G0282123	DDB_G0282123	NA
chr3	5423413	5425035	+	DDB_G0282137	DDB_G0282137	related to sterol desaturase
chr3	5425596	5428416	+	DDB_G0282125	DDB_G0282125	similar to D. purpureum protein
chr3	5429045	5430156	+	DDB_G0282127	DDB_G0282127	NA
chr3	5430867	5433164	+	DDB_G0282129	DDB_G0282129	NA
chr3	5434030	5437017	+	DDB_G0282139	DDB_G0282139	NA
chr3	5439955	5443028	+	DDB_G0282145	ptpC	NA
chr3	5443128	5445837	-	DDB_G0282181	nvl	ortholog of H. sapiens NVL and S. cerevisiae RIX7 invovled in export of ribosomal subunits from the nucleus
chr3	5446691	5453488	+	DDB_G0282149	DDB_G0282149	NA
chr3	5453620	5455251	-	DDB_G0282183	cyp513A1	NA
chr3	5456198	5458674	+	DDB_G0282151	DDB_G0282151	NA
chr3	5458911	5460478	-	DDB_G0282147	fadB	contains the histidine box motif characteristic of fatty acid desaturases%3B expressed in pstO cells and upper cup during culmination
chr3	5460939	5461716	-	DDB_G0282153	aplH	NA
chr3	5462477	5463732	-	DDB_G0282155	DDB_G0282155	NA
chr3	5463972	5466440	-	DDB_G0282185	DDB_G0282185	NA
chr3	5467686	5469353	+	DDB_G0282157	DDB_G0282157	NA
chr3	5469433	5471067	-	DDB_G0282159	DDB_G0282159	NA
chr3	5471894	5473402	+	DDB_G0282161	DDB_G0282161	similar to small ubiquitin-related modifier (SUMO)%2C however%2C the encoded protein is much larger
chr3	5473812	5474718	+	DDB_G0347907	DDB_G0347907	NA
chr3	5474915	5476996	+	DDB_G0347908	DDB_G0347908	NA
chr3	5477142	5477912	+	DDB_G0282165	DDB_G0282165	NA
chr3	5478048	5479370	-	DDB_G0282167	DDB_G0282167	NA
chr3	5479724	5481160	-	DDB_G0282169	DDB_G0282169	NA
chr3	5481850	5482307	+	DDB_G0282141	hatA	histidine-rich%2C pH-dependent%2C actin binding protein%3B N-terminal myristoylation
chr3	5482925	5483386	+	DDB_G0282143	hatB	histidine-rich%2C pH-dependent%2C actin binding protein%3B N-terminal myristoylation
chr3	5485189	5486044	-	DDB_G0282171	DDB_G0282171	NA
chr3	5487367	5489804	+	DDB_G0282175	grlF	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr3	5490516	5491077	+	DDB_G0282177	DDB_G0282177	contains one ML (MD-2-related lipid recognition) domain%3B similar to fungal proteins of the NPC2 family%3B contains a predicted signal peptide
chr3	5491825	5492262	+	DDB_G0282179	DDB_G0282179	contains one ML (MD-2-related lipid recognition) domain%3B similar to fungal proteins of the NPC2 family%3B contains a predicted signal peptide
chr3	5492546	5495583	-	DDB_G0282187	DDB_G0282187	NA
chr3	5497711	5499541	+	DDB_G0282283	cyp515B1	enriched in prestalk cells
chr3	5500018	5504728	+	DDB_G0282191	polA1	ortholog of the catalytic subunit of the DNA polymerase alpha-primase complex%2C required for the initiation of DNA replication
chr3	5505181	5505851	+	DDB_G0282193	DDB_G0282193	NA
chr3	5506037	5506499	-	DDB_G0282195	timm16	conserved component of the mitochondrial presequence translocase-associated protein import motor (PAM) required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix
chr3	5507533	5509512	+	DDB_G0282197	DDB_G0282197	NA
chr3	5509670	5511227	-	DDB_G0295673	atg17	similar to yeast ATG17 (autophagy related 17) required for activation of ATG1 protein kinase
chr3	5511594	5513276	-	DDB_G0282285	DDB_G0282285	contains an N-terminal F-box domain and an ApaG domain which is found at the C-terminus of F-box proteins
chr3	5513834	5515875	+	DDB_G0282199	allB1	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B allantoin %3C%3D%3E allantoate
chr3	5515941	5517965	-	DDB_G0282201	DDB_G0282201	NA
chr3	5518229	5518299	+	DDB_G0295065	tRNA-Pro-UGG-11	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr3	5519054	5519124	-	DDB_G0295103	tRNA-Pro-UGG-12	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr3	5519409	5520119	-	DDB_G0282203	rabY	NA
chr3	5520305	5522013	-	DDB_G0282207	DDB_G0282207_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0292188%22%3EDDB_G0292188%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269482%22%3EDDB_G0269482%3C%2Fa%3E
chr3	5522317	5524513	-	DDB_G0282209	DDB_G0282209	weakly related to Sec23%2FSec24 involved in COPII-coated vesicles intracellular transport
chr3	5525043	5526594	+	DDB_G0282211	DDB_G0282211	similar to D. purpureum protein
chr3	5526720	5528464	-	DDB_G0282213	DDB_G0282213	NA
chr3	5528630	5530592	-	DDB_G0282215	DDB_G0282215	NA
chr3	5530765	5532147	-	DDB_G0282219	mfap1	ortholog of MFAP1%2C a component of elastin-associated microfibrils in the extracellular matrix in beef%3B no signal peptide detected in the Dictyostelium gene
chr3	5532383	5536679	+	DDB_G0282221	DDB_G0282221	NA
chr3	5536930	5539307	+	DDB_G0282223	DDB_G0282223	NA
chr3	5540643	5542909	+	DDB_G0282225	DDB_G0282225	NA
chr3	5543803	5546169	+	DDB_G0282227	DDB_G0282227	NA
chr3	5546265	5548140	-	DDB_G0282287	DDB_G0282287	NA
chr3	5549011	5550148	-	DDB_G0282229	DDB_G0282229	NA
chr3	5550968	5553004	+	DDB_G0282233	DDB_G0282233	NA
chr3	5553806	5555127	+	DDB_G0282235	rfc5	ortholog of %3Ci%3EH. sapiens%3C%2Fi%3E RFC5 (36 kDa subunit) and %3Ci%3ES. cerevisiae%3C%2Fi%3E RFC3
chr3	5556336	5559347	-	DDB_G0282237	DDB_G0282237	similar to Arabidopsis thaliana DDT domain-containing protein (GenBank NP_196480)
chr3	5559700	5561218	-	DDB_G0282239	DDB_G0282239	very similar to the uncharacterized %3Ci%3EH. sapiens %3C%2Fi%3E C9orf41
chr3	5561439	5563916	+	DDB_G0282241	DDB_G0282241	NA
chr3	5564223	5564709	+	DDB_G0282243	nhp2l1	ortholog of human NHP2L1%2C which is believed to play a role in spliceosome assembly%3B similar to ribosomal protein L7AE but is not likely to be a ribosomal protein
chr3	5565585	5569532	+	DDB_G0282245	forD	NA
chr3	5570015	5571588	-	DDB_G0282247	rapgapB	required for the correct sorting behavior of different cell types during development%3B defects in RapGAPB affect prestalk and prespore cell adhesion
chr3	5574241	5576373	+	DDB_G0282189	tupA	NA
chr3	5576769	5578232	-	DDB_G0282251	DDB_G0282251	NA
chr3	5579342	5579808	+	DDB_G0282253	DDB_G0282253	NA
chr3	5579876	5581670	-	DDB_G0282255	DDB_G0282255	NA
chr3	5583350	5583949	+	DDB_G0282257	DDB_G0282257	NA
chr3	5584485	5585237	+	DDB_G0282259	DDB_G0282259	NA
chr3	5585355	5586328	-	DDB_G0282261	ech1	very conserved among prokaryotes and eukaryotes%3B isomerizes 3-trans%2C5-cis-dienoyl-CoA to 2-trans%2C4-trans-dienoyl-CoA
chr3	5586895	5589681	+	DDB_G0282263	DDB_G0282263	NA
chr3	5590476	5592144	+	DDB_G0282265	sgmC	hydrolyze the phosphodiester bond in sphingomyelin to form ceramide
chr3	5592466	5593048	+	DDB_G0282267	DDB_G0282267	similar to FKBP-type peptidyl-prolyl isomerase%2C which functions as a receptor for immunosuppressants in vertebrates
chr3	5594139	5594948	+	DDB_G0282269	DDB_G0282269	NA
chr3	5595367	5597368	+	DDB_G0282271	gxcV	NA
chr3	5598918	5599878	+	DDB_G0282275	DDB_G0282275	NA
chr3	5600791	5601411	+	DDB_G0282279	DDB_G0282279	NA
chr3	5601674	5602159	-	DDB_G0282281	DDB_G0282281	NA
chr3	5602431	5603475	-	DDB_G0282351	DDB_G0282351	NA
chr3	5604394	5606049	-	DDB_G0282293	rnpA	regulated by the MADS-box transcription factor SrfA during development
chr3	5607244	5609831	-	DDB_G0282299	DDB_G0282299	highly similar to NAD-dependent DNA ligase found in bacteria
chr3	5610071	5610561	+	DDB_G0282301	DDB_G0282301	NA
chr3	5610805	5613253	-	DDB_G0282303	DDB_G0282303	NA
chr3	5613858	5616404	-	DDB_G0282305	DDB_G0282305	NA
chr3	5618181	5618719	-	DDB_G0282307	DDB_G0282307	NA
chr3	5621318	5624547	+	DDB_G0282311	DDB_G0282311	transporter protein with 12 putative transmembrane domains
chr3	5624970	5626340	-	DDB_G0282313	DDB_G0282313	putative molecular chaperone
chr3	5627326	5627680	+	DDB_G0282315	DDB_G0282315	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282317%22%3E%3Ci%3EDDB_G0282317%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282319%22%3E%3Ci%3EDDB_G0282319%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282321%22%3E%3Ci%3EDDB_G0282321%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282323%22%3E%3Ci%3EDDB_G0282323%3C%2Fi%3E%3C%2Fa%3E 
chr3	5628480	5628840	+	DDB_G0282317	DDB_G0282317	underexpressed in gskA-null strain%3B highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282315%22%3E%3Ci%3EDDB_G0282315%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282319%22%3E%3Ci%3EDDB_G0282319%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282321%22%3E%3Ci%3EDDB_G0282321%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282323%22%3E%3Ci%3EDDB_G0282323%3C%2Fi%3E%3C%2Fa%3E 
chr3	5629614	5629961	+	DDB_G0282319	DDB_G0282319	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282315%22%3E%3Ci%3EDDB_G0282315%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282323%22%3E%3Ci%3EDDB_G0282323%3C%2Fi%3E%3C%2Fa%3E 
chr3	5630697	5631035	+	DDB_G0282321	DDB_G0282321	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282315%22%3E%3Ci%3EDDB_G0282315%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282323%22%3E%3Ci%3EDDB_G0282323%3C%2Fi%3E%3C%2Fa%3E 
chr3	5631690	5632034	+	DDB_G0282323	DDB_G0282323	highly similar to neighboring genes%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282315%22%3E%3Ci%3EDDB_G0282315%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282321%22%3E%3Ci%3EDDB_G0282321%3C%2Fi%3E%3C%2Fa%3E 
chr3	5632424	5637271	-	DDB_G0282289	dhkD	NA
chr3	5639999	5641144	+	DDB_G0282295	ubqA	NA
chr3	5641699	5645174	+	DDB_G0282297	forB	NA
chr3	5645911	5646187	+	DDB_G0282325	DDB_G0282325	highly similar to neighboring gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282327%22%3E%3Ci%3EDDB_G0282327%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E%3B negatively regulated by STATa
chr3	5647342	5647588	+	DDB_G0282327	DDB_G0282327	highly similar to neighboring gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0282325%22%3E%3Ci%3EDDB_G0282325%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr3	5648019	5649047	-	DDB_G0282329	DDB_G0282329	NA
chr3	5649510	5649854	-	DDB_G0282331	DDB_G0282331	NA
chr3	5651269	5651940	-	DDB_G0282333	DDB_G0282333	NA
chr3	5652642	5653270	-	DDB_G0282335	DDB_G0282335_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr3	5652919	5652991	+	DDB_G0295067	tRNA-Lys-CUU-6	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5654004	5654076	-	DDB_G0295101	tRNA-Arg-UCU-7	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5654662	5656554	+	DDB_G0282337	DDB_G0282337	contains one C2 domain and one EF hand domain
chr3	5656917	5658092	+	DDB_G0282339	rpa5	subunit common to RNA polymerases I and III%3B ortholog of H. sapiens RPA5 S. cerevisiae RPC40
chr3	5658262	5659241	-	DDB_G0282341	DDB_G0282341	belongs to the crotonase superfamily%3B contains a predicted peroxisomal targeting signal
chr3	5660192	5663954	+	DDB_G0282291	potA	similar to calcium-activated potassium channel
chr3	5664216	5665836	-	DDB_G0282353	cyp513E1	NA
chr3	5666499	5666894	+	DDB_G0349537	DDB_G0349537	NA
chr3	5668014	5669666	-	DDB_G0282347	cyp513E2_ps	putative pseudogene%3B related to the cytochrome P450 family
chr3	5669895	5671717	-	DDB_G0282349	cyp513E3_ps	putative pseudogene%3B related to the cytochrome P450 family
chr3	5672383	5674703	+	DDB_G0282355	DDB_G0282355_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr3	5676395	5676793	+	DDB_G0282751	DDB_G0282751_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr3	5677651	5682185	-	DDB_G0282753	DDB_G0282753_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr3	5679957	5680052	-	DDB_G0295099	tRNA-Ser-CGA-1	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5684660	5685426	+	DDB_G0282359	ppiA	PPIases accelerate protein folding%3B expressed in prespore cells
chr3	5685837	5686087	-	DDB_G0282383	DDB_G0282383	NA
chr3	5686594	5689568	-	DDB_G0282385	DDB_G0282385	NA
chr3	5690073	5691388	+	DDB_G0282387	DDB_G0282387	has similarity to mammalian exonuclease 3%27-5%27 domain-like-containing protein 1 (EXDL1)
chr3	5691748	5692463	+	DDB_G0282389	DDB_G0282389	NA
chr3	5692688	5694949	-	DDB_G0282391	DDB_G0282391	NA
chr3	5695519	5696365	+	DDB_G0282393	DDB_G0282393	NA
chr3	5696610	5698400	-	DDB_G0282395	gacQ	NA
chr3	5699822	5703817	-	DDB_G0282397	mbtps1	ortholog of H. sapiens MBTPS1%2C which catalyzes the first step in the proteolytic activation of sterol regulatory element-binding proteins (SREBPs)
chr3	5704423	5704681	-	DDB_G0282399	DDB_G0282399	NA
chr3	5705279	5705529	+	DDB_G0282401	DDB_G0282401	NA
chr3	5705899	5706096	+	DDB_G0282403	DDB_G0282403	NA
chr3	5706517	5706587	-	DDB_G0295097	tRNA-Gly-UCC-3	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	5706954	5707024	-	DDB_G0295095	tRNA-Gly-UCC-2	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr3	5707254	5708273	+	DDB_G0282755	DDB_G0282755_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr3	5708573	5709691	+	DDB_G0282405	DDB_G0282405_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5710802	5713235	-	DDB_G0282407	DDB_G0282407	NA
chr3	5714264	5717976	+	DDB_G0282409	DDB_G0282409	weakly similar to M. musculus bromodomain-containing protein BP75 (SwissProt O88665)
chr3	5721347	5723844	+	DDB_G0282411	DDB_G0282411	NA
chr3	5724206	5724763	+	DDB_G0282413	DDB_G0282413	NA
chr3	5726442	5733682	+	DDB_G0282377	dhkM	required for vacuolization during autophagic cell death
chr3	5735049	5735769	+	DDB_G0282415	DDB_G0282415	NA
chr3	5736810	5738483	+	DDB_G0282417	DDB_G0282417	similar to Arabidopsis thaliana receptor-like protein kinase
chr3	5739737	5740729	-	DDB_G0282363	psmA1	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)%3B suppressor of tagB-stb10
chr3	5741356	5742554	+	DDB_G0282367	selD	contains a selenocysteine residue (U) at position 25%3B catalyzes the reaction ATP %2B selenide %2B H%3Csub%3E2%3C%2Fsub%3EO %3D AMP %2B selenophosphate %2B phosphate
chr3	5743012	5744627	-	DDB_G0282419	cyp508B1	NA
chr3	5745445	5749806	+	DDB_G0282421	DDB_G0282421	NA
chr3	5750022	5750468	-	DDB_G0282423	ponD	similar to ponticulins%2C especially ponB%3B ponA is a protein that anchors the actin cytoskeleton to the plasma membrane
chr3	5751386	5751467	+	DDB_G0295069	tRNA-Ser-UGA-6	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5752284	5755235	-	DDB_G0282425	DDB_G0282425	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0282425 may well be related the yeast transcriptional regulator ADA3%2C which is widely conserved in fungi and animals. The gene is the first and only BLAST hit in Dicty using the mouse%2C Ciona%2C and Nematostella sequences as bait. The homology with the yeast or Ustilago sequences is much lower%2C but DDB_G0282425 is still the first hit. When blasted out against the NCBI data base%2C DDB_G0282425 hits many putative ADA3 orthologs. Sequences recognizable as ADA3 do not appear to occur in plants. %3Ci%3EHarry MacWilliams%2C May 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0282425%22%3E There is more information on the wiki page%3C%2Fa%3E
chr3	5755702	5758268	+	DDB_G0282427	DDB_G0282427	shared a short region of similarity with histone-lysine N-methyltransferase%2C H3 lysine-4 specific MLL3%3B contains a single HMG1%2F2 box
chr3	5758659	5759806	-	DDB_G0282429	DDB_G0282429	protein serine%2Fthreonine kinase%2C CAMK group%2C CAMK1 family%3B similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases
chr3	5762312	5762476	+	DDB_G0282757	DDB_G0282757	NA
chr3	5763247	5764563	+	DDB_G0282431	DDB_G0282431	NA
chr3	5764726	5765343	-	DDB_G0282433	DDB_G0282433	NA
chr3	5765614	5766175	-	DDB_G0282435	DDB_G0282435	NA
chr3	5767462	5767949	-	DDB_G0282437	DDB_G0282437_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0282427%22%3EDDB_G0282427%3C%2Fa%3E 
chr3	5768407	5768865	-	DDB_G0282439	DDB_G0282439	NA
chr3	5769357	5769837	-	DDB_G0282441	DDB_G0282441	NA
chr3	5770557	5770946	-	DDB_G0282443	DDB_G0282443	NA
chr3	5771651	5772053	-	DDB_G0282445	DDB_G0282445	NA
chr3	5772493	5772774	-	DDB_G0282447	DDB_G0282447	NA
chr3	5773378	5774178	-	DDB_G0282449	DDB_G0282449	NA
chr3	5774365	5774968	+	DDB_G0282451	DDB_G0282451	NA
chr3	5775152	5777030	-	DDB_G0282759	DDB_G0282759	NA
chr3	5777523	5779929	+	DDB_G0282453	med1	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 1%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr3	5781008	5781208	+	DDB_G0282455	DDB_G0282455	NA
chr3	5781580	5781660	-	DDB_G0295093	tRNA-Ser-GCU-6	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5783278	5783871	-	DDB_G0282457	arrA	NA
chr3	5785479	5787871	+	DDB_G0282459	grlH	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr3	5789478	5791965	+	DDB_G0282461	grlC	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr3	5792759	5795247	+	DDB_G0282463	DDB_G0282463	contains a glycoside hydrolase carbohydrate-binding domain and a peptidase C19 ubiquitin carboxyl-terminal hydrolase domain
chr3	5795939	5800480	+	DDB_G0295771	DDB_G0295771	NA
chr3	5800686	5801114	+	DDB_G0282465	DDB_G0282465	NA
chr3	5801585	5804780	-	DDB_G0282761	DDB_G0282761	NA
chr3	5805820	5807271	+	DDB_G0282467	DDB_G0282467	catalyzes the reaction S-adenosyl-L-methionine %3C%3D%3E 1-aminocyclopropane-1-carboxylate %2B methylthioadenosine
chr3	5807533	5809539	-	DDB_G0282469	gnt13	CAZy family GT49%3B similar to vertebrate acetylglucosaminyltransferase-like protein
chr3	5811380	5815420	+	DDB_G0282471	DDB_G0282471	NA
chr3	5815575	5817857	-	DDB_G0282473	ints9	ortholog of integrator complex subunit 9%2C component of a multiprotein mediator of small nuclear RNA processing
chr3	5819048	5821924	+	DDB_G0282475	gxcF	NA
chr3	5822316	5822710	+	DDB_G0282477	DDB_G0282477	NA
chr3	5822824	5823706	-	DDB_G0282763	spf27	ortholog of the mammalian BCAS2 (breast carcinoma amplified sequence 2) protein%2C a spliceosome-associated protein
chr3	5825075	5826323	+	DDB_G0282361	prlA	NA
chr3	5826574	5827634	-	DDB_G0282479	DDB_G0282479	NA
chr3	5828096	5828706	-	DDB_G0282481	DDB_G0282481	NA
chr3	5829856	5831090	+	DDB_G0282483	DDB_G0282483	NA
chr3	5831395	5832513	-	DDB_G0282485	cepB	localizes to the centrosome
chr3	5832783	5833825	+	DDB_G0282765	DDB_G0282765	NA
chr3	5834821	5835877	+	DDB_G0282487	DDB_G0282487	NA
chr3	5835955	5838780	-	DDB_G0282489	mhkD	belongs to the Atypical Alpha protein kinases%2C highly similar to Dictyostelium mhkA%3B contains N-terminal predicted coiled-coil domain%3B contains C-terminal G-protein beta WD-40 repeats
chr3	5839851	5842502	-	DDB_G0282491	DDB_G0282491	contains two WD-40 repeat regions
chr3	5845721	5847037	-	DDB_G0282493	aatB	catalyzes the reaction oxaloacetate %2B L-glutamate %3C%3D%3E L-aspartate %2B %26alpha%3B-ketoglutarate%3B likely to be cytoplasmic
chr3	5848284	5849305	-	DDB_G0282495	DDB_G0282495	NA
chr3	5849588	5850358	-	DDB_G0282497	DDB_G0282497	NA
chr3	5850862	5853669	-	DDB_G0282499	DDB_G0282499	%3Cb%3ECommunity annotation:%3C%2Fb%3E Transcriptional modulators of the E2F family fall into two groups. Both groups have othologs in animals and plants and thus appear to be ancient. The better known group%2C represented by animal E2F1-3 and E2Fs a%2C b and c of Arabidopsis%2C consists of proteins which form heterodimers with the %22dimerization partner%22%2C DP. E2F and DP each contribute half of the DNA binding motif of the dimer. In animals%2C further members of this group are found which have lost the transactivation domain%2C and appear to function as transcriptional repressors%3B examples are E2F4-6. Proteins in the second group%2C which includes animal E2F7-8 and DEL1-3 of Arabidopsis%2C are thought to act as monomers. Proteins of this group were discovered relatively recently%3B their roles appear to include proliferation control but are not limited to this. %3Cbr%3E Blast searches in D. discoideum turn up one heterodimeric E2F protein (DDB_G0284129) but none in the second group. However%2C when the search universe is extended to include other cellular slime molds%2C good orthologs of monomeric E2Fs are recovered from Polysphondylium and D. fasciculatum. When these are blasted into Dd%2C they hit DDB_G0271994 and DDB_G0282499 with respectable e-values. The Dd proteins appear to be highly diverged%2C so that the E2F binding domains are barely recognizable%2C if at all. When they are blasted back to the human proteome%2C the first hits are nonetheless to E2F7%2C albeit at marginal e-value. Tree-building algorithms support the idea that these proteins belong in in the monomeric E2F group. %3Ci%3EHarry MacWilliams%2C February 2011%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0282499%22%3E There is more information and graphics on the wiki page%3C%2Fa%3E
chr3	5855098	5858238	+	DDB_G0282501	DDB_G0282501	NA
chr3	5858325	5859386	-	DDB_G0282767	DDB_G0282767	NA
chr3	5859831	5861526	-	DDB_G0282769	cyp522A1	NA
chr3	5861766	5862763	-	DDB_G0282771	DDB_G0282771_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0278909%22%3EDDB_G0278909%3C%2Fa%3E
chr3	5863004	5863633	+	DDB_G0282503	tmc_ps1	putative pseudogene%3B similar to a gene family in Dictyostelium%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289207%22%3EtmcB%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0289253%22%3EtmcC%3C%2Fa%3E
chr3	5866236	5867570	-	DDB_G0282507	DDB_G0282507_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5868008	5868081	+	DDB_G0295071	tRNA-Val-AAC-14	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5869400	5869903	-	DDB_G0282509	DDB_G0282509_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5870128	5870201	+	DDB_G0295073	tRNA-Val-AAC-15	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5870598	5871757	+	DDB_G0282511	DDB_G0282511	NA
chr3	5872000	5873811	-	DDB_G0282513	DDB_G0282513	NA
chr3	5873962	5876256	-	DDB_G0282515	DDB_G0282515	NA
chr3	5877016	5878111	-	DDB_G0282517	DDB_G0282517	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr3	5878544	5879689	-	DDB_G0282369	ubqG	NA
chr3	5880253	5880529	+	DDB_G0282519	DDB_G0282519	NA
chr3	5880742	5884093	-	DDB_G0282521	DDB_G0282521	NA
chr3	5884670	5884801	+	DDB_G0282773	DDB_G0282773	NA
chr3	5885598	5885872	+	DDB_G0282523	DDB_G0282523	NA
chr3	5886297	5887636	+	DDB_G0282525	DDB_G0282525	NA
chr3	5888056	5888814	+	DDB_G0282527	pemtA	homolog of mammalian PEMT and S. cerevisiae OPI3%2C which catalyzes the steps in phosphatidylcholine biosynthesis
chr3	5888997	5890360	-	DDB_G0282529	rbbD	similar to H. sapiens Retinoblastoma binding proteins RBBP4 and RBBP7 and S. cerevisiae HAT2%2C a subunit of the HAT1%2FHAT2 histone acetyltransferase complex
chr3	5890637	5891733	-	DDB_G0282531	DDB_G0282531	ortholog of human Tat DNase 1 (TATDN1)%3B belongs to a large superfamily of metalloenzymes
chr3	5893579	5894082	+	DDB_G0282533	DDB_G0282533	NA
chr3	5894376	5896223	-	DDB_G0282535	DDB_G0282535	NA
chr3	5897353	5898018	-	DDB_G0282537	rabS	NA
chr3	5898457	5898537	+	DDB_G0295075	tRNA-Ser-GCU-3	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5899632	5901257	-	DDB_G0282539	nagB	catalyses the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
chr3	5902227	5902706	-	DDB_G0282541	DDB_G0282541_RTE	Part of ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-C%3B refer to GenBank AF298210 for partially assembled consensus element
chr3	5902871	5902951	+	DDB_G0295077	tRNA-Ser-GCU-4	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5905421	5906545	-	DDB_G0282543	DDB_G0282543_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5906903	5906983	+	DDB_G0295079	tRNA-Ser-GCU-5	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5907328	5907956	+	DDB_G0282775	spt16_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0282677 %22%3E%3Ci%3Espt16%3C%2Fi%3E%3C%2Fa%3E
chr3	5908362	5910463	+	DDB_G0282777	DDB_G0282777	kinase domain similar to yeast cdc5%2C a serine%2Fthreonine kinase with multiple functions in mitosis and cytokinesis
chr3	5911017	5913816	-	DDB_G0282779	DDB_G0282779_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0292606%22%3EDDB_G0292606%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0282673%22%3EDDB_G0282673%3C%2Fa%3E
chr3	5913844	5916922	-	DDB_G0282781	DDB_G0282781_ps	putative pseudogene%3B similar to a family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0295771%22%3EDDB_G0295771%3C%2Fa%3E
chr3	5917328	5918251	-	DDB_G0282549	DDB_G0282549	NA
chr3	5918532	5918603	+	DDB_G0295081	tRNA-Thr-AGU-16	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5918974	5919270	-	DDB_G0282551	DDB_G0282551	weakly related to hssA%2F2C%2F7E family protein
chr3	5920217	5920290	-	DDB_G0282553	DDB_G0282553_ps	putative pseudogene%3B belongs to a family of small Dictyostelium-specific proteins
chr3	5921147	5930200	+	DDB_G0282783	DDB_G0282783	similar to a %3Ci%3ED. purpureum%3C%2Fi%3E protein
chr3	5930270	5932022	-	DDB_G0282555	DDB_G0282555	NA
chr3	5932394	5934183	-	DDB_G0282557	DDB_G0282557	NA
chr3	5934889	5936399	-	DDB_G0282559	dduA	downregulated in the uninfected %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr3	5936624	5937975	+	DDB_G0282785	DDB_G0282785_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5937248	5937329	-	DDB_G0295091	tRNA-Leu-AAG-3	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5938105	5938347	+	DDB_G0282561	DDB_G0282561_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	5938746	5940733	-	DDB_G0282787	DDB_G0282787_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr3	5940507	5940580	-	DDB_G0295089	tRNA-Val-AAC-17	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5941283	5943136	-	DDB_G0282563	DDB_G0282563	NA
chr3	5943856	5945484	+	DDB_G0282565	DDB_G0282565	NA
chr3	5945975	5947124	+	DDB_G0282567	DDB_G0282567	NA
chr3	5947254	5951124	-	DDB_G0282569	sf3b3	subunit of the splicing factor SF3B required for spliceosome assembly
chr3	5952908	5953252	+	DDB_G0282571	DDB_G0282571	NA
chr3	5953713	5955298	+	DDB_G0282573	DDB_G0282573	NA
chr3	5957238	5960822	+	DDB_G0282575	DDB_G0282575	NA
chr3	5960962	5965035	-	DDB_G0282577	DDB_G0282577	NA
chr3	5966744	5968161	+	DDB_G0282579	pldZ	highly similar to mammalian PLD3%2C which is of unknown function
chr3	5969861	5971133	+	DDB_G0282581	wdr45l	ortholog of the conserved WDR45 like protein that is up-regulated in a variety of human cancers%3B contains 3 WD-40 repeats
chr3	5972121	5972733	-	DDB_G0282583	DDB_G0282583	contains one RGS domain%3B similar to human RGS1 (regulator of G-protein signalling) which inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits
chr3	5975167	5975485	-	DDB_G0282585	DDB_G0282585	NA
chr3	5977758	5978628	+	DDB_G0282587	DDB_G0282587	NA
chr3	5978839	5979513	-	DDB_G0282589	DDB_G0282589	NA
chr3	5980059	5981149	-	DDB_G0282591	omt7	NA
chr3	5981778	5981849	+	DDB_G0295083	tRNA-Thr-AGU-17	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr3	5983138	5984226	-	DDB_G0282593	DDB_G0282593	ortholog of human FAM50A%2C a XAP5 protein found in the nucleus with potential DNA binding activity
chr3	5984604	5985197	-	DDB_G0282595	gmfA	glia maturation factor homolog%3B initially identified as a growth and differentiation factor in mammals
chr3	5985770	5989281	+	DDB_G0282597	DDB_G0282597	NA
chr3	5989441	5990577	-	DDB_G0282599	DDB_G0282599	NA
chr3	5991308	5992503	+	DDB_G0282601	rps11	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S11 homolog
chr3	5993046	5993891	+	DDB_G0282603	DDB_G0282603	similar to human NUDT5 (ADP-sugar pyrophosphatase) and S. cerevisiae YSA1 (ADP-ribose pyrophosphatase)
chr3	5993980	5995716	-	DDB_G0282605	DDB_G0282605	NA
chr3	5996864	5998409	-	DDB_G0282607	crsA	catalyzes the reaction acyl-CoA %2B sphingosine %3D CoA %2B N-acylsphingosine in ceramide synthesis%3B ortholog of %3Ci%3ES. cerevisiae%3C%2Fi%3E LAG1 and %3Ci%3EH. sapiens%3C%2Fi%3E TRH1
chr3	5999479	5999766	-	DDB_G0282609	DDB_G0282609	contains a predicted signal peptide
chr3	6001079	6002350	+	DDB_G0282611	DDB_G0282611	catalyzes the reactoin CTP %2B (R)-4%27-phosphopantothenate %2B L-cysteine %3D CMP %2B diphosphate %2B N-[(R)-4%27-phosphopantothenoyl]-L-cysteine
chr3	6002359	6002949	-	DDB_G0282613	DDB_G0282613	NA
chr3	6003476	6005010	+	DDB_G0282615	midA	conserved protein required for mitochondrial complex I assembly both in Dictyostelium and in human%3B interacts with the mitochondrial complex I protein %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2Fnad7%22%3E%3Ci%3Endufs2%3C%2Fa%3E 
chr3	6005174	6006260	-	DDB_G0282617	psmF1	inhibitor subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr3	6007141	6007848	+	DDB_G0282619	DDB_G0282619	NA
chr3	6009133	6009453	+	DDB_G0282621	DDB_G0282621	NA
chr3	6010118	6012946	+	DDB_G0282623	wdr3	ortholog of H. sapiens WDR3 and S. cerevisiae DIP2
chr3	6013022	6018337	-	DDB_G0282625	pikG	putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring%3B has the capacity to bind and be activated by the GTP-bound small GTPase ras
chr3	6019111	6025130	+	DDB_G0282627	vps15	putative protein serine%2Fthreonine kinase%3B similar to human PIK3R4 and yeast VPS15%2C which regulate the phosphatidylinositol 3 kinase VPS34 (hVps34)%3B yeast VPS15%2FVPS34 complex known to be involved in vacuolar protein sorting
chr3	6026305	6029004	+	DDB_G0282629	DDB_G0282629	NA
chr3	6029325	6030187	-	DDB_G0282631	DDB_G0282631	NA
chr3	6031309	6034199	+	DDB_G0282633	DDB_G0282633	conserved hypothetical multidomain protein
chr3	6034361	6035654	-	DDB_G0282635	DDB_G0282635	NA
chr3	6035957	6036376	+	DDB_G0282637	DDB_G0282637	NA
chr3	6037460	6044628	+	DDB_G0282639	DDB_G0282639	NA
chr3	6045140	6045859	-	DDB_G0282365	rac1C	NA
chr3	6046495	6046889	+	DDB_G0282791	DDB_G0282791_ps	putative pseudogene%3B small fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0282641%22%3EDDB_G0282641%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0277301%22%3EDDB_G0277301%3C%2Fa%3E
chr3	6047385	6051329	+	DDB_G0282641	DDB_G0282641	member of a Dictyostelium-specific gene family
chr3	6051875	6053154	+	DDB_G0282643	DDB_G0282643	conserved hypothetical protein%3B contains a putative signal peptide
chr3	6053393	6053908	-	DDB_G0282645	DDB_G0282645	NA
chr3	6054472	6055522	+	DDB_G0282647	DDB_G0282647	weakly similar to Rab small GTPases
chr3	6055905	6057036	+	DDB_G0294577	DDB_G0294577	NA
chr3	6057374	6058267	+	DDB_G0282649	DDB_G0282649_ps	putative pseudogene%3B Rab family protein
chr3	6058470	6059318	+	DDB_G0282651	rsmN	NA
chr3	6060135	6060989	+	DDB_G0282653	DDB_G0282653	NA
chr3	6061184	6061582	-	DDB_G0282379	rpl28	protein component of the large (60S) ribosomal subunit
chr3	6063029	6063729	-	DDB_G0282655	DDB_G0282655	conserved protein of unknown function
chr3	6064156	6065672	+	DDB_G0282793	wdr61	NA
chr3	6065769	6066293	-	DDB_G0282657	DDB_G0282657	NA
chr3	6067799	6071194	+	DDB_G0282795	DDB_G0282795	contains two coiled-coil domains
chr3	6072152	6072224	+	DDB_G0295085	tRNA-Ile-AAU-8	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr3	6073164	6076307	-	DDB_G0282797	DDB_G0282797_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	6076598	6077932	-	DDB_G0282799	DDB_G0282799_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr3	6078780	6078853	+	DDB_G0295087	tRNA-Val-AAC-16	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr3	6079285	6079926	+	DDB_G0282659	DDB_G0282659_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr3	6080613	6081766	+	DDB_G0282371	veg111	NA
chr3	6081891	6091580	-	DDB_G0282801	DDB_G0282801	conserved protein
chr3	6092418	6093399	+	DDB_G0282661	DDB_G0282661	NA
chr3	6093593	6094207	+	DDB_G0282665	DDB_G0282665_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0282661%22%3EDDB_G0282661%3C%2Fa%3E 
chr3	6096363	6098133	+	DDB_G0282667	DDB_G0282667	contains an N-terminal F-box domain and five Kelch repeats
chr3	6098622	6100010	+	DDB_G0282671	DDB_G0282671_ps	putative pseudogene%3B weakly similar to AGC protein kinases%3B does not contain the consensus sequences required for kinase function
chr3	6100946	6102478	+	DDB_G0282673	DDB_G0282673	NA
chr3	6103495	6105520	-	DDB_G0282675	DDB_G0282675_ps	putative pseudogene%3B very similar to %3Ci%3EDictyostelium%3C%2Fi%3E DDB_G0282777%2C a putative serine%2Fthreonine kinase
chr3	6105920	6109250	-	DDB_G0282677	spt16	similar to SPT16 of the FACT complex%2C a heterodimer of ssrp1 and spt16%3B the FACT complex is a general chromatin factor that acts to reorganize nucleosomes%2C involved in multiple processes that require DNA as a template such as mRNA elongation%2C DNA replication and DNA repair
chr3	6110131	6114510	+	DDB_G0282679	DDB_G0282679	NA
chr3	6115450	6116404	+	DDB_G0282681	DDB_G0282681_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0267600%22%3EDDB_G0267600%3Ca%2F%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0267598%22%3EDDB_G0267598%3Ca%2F%3E
chr3	6118341	6122724	+	DDB_G0282373	gbpD	guanine nucleotide exchange factor for Rap1%3B involved in cell-substrate adhesion
chr3	6123377	6123829	+	DDB_G0282683	DDB_G0282683	NA
chr3	6124057	6125277	-	DDB_G0282803	rcl1	NA
chr3	6125852	6127432	-	DDB_G0282685	DDB_G0282685	NA
chr3	6128420	6131150	-	DDB_G0282689	DDB_G0282689	NA
chr3	6131868	6132842	+	DDB_G0282357	pksB	ortholog of E. coli ydfG and S. cerevisiae TMA29%2C that have NADP%2B-dependent L-serine dehydrogenase activity%3B also acts on other amino acids such as D-threonine and L-%3Ci%3Eallo%3C%2Fi%3E-threonine%3B homotetramer  
chr3	6132903	6134747	-	DDB_G0349427	DDB_G0349427	NA
chr3	6135302	6135754	-	DDB_G0349426	DDB_G0349426	NA
chr3	6137089	6138534	-	DDB_G0282693	pex10	ortholog of peroxin 10%2C a RING finger peroxisomal membrane peroxin required for peroxisomal matrix protein import%3B in S. cerevisiae%2C interacts with peroxin 12%2C links ubiquitin-conjugating peroxin 4 to protein import machinery%3B mutations in human homolog cause a variety of peroxisomal disorders
chr3	6139156	6141114	+	DDB_G0282695	DDB_G0282695	C-terminal region similar to P-loop nucleotide triphosphate hydrolases
chr3	6144529	6146082	+	DDB_G0282697	nfyA	putative ortholog of the A subunit of the heterotrimeric transcription factor NFY%2C composed of NfyA%2C NfyB%2C and NfyC
chr3	6147705	6148849	-	DDB_G0282807	DDB_G0282807_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0290635%22%3EDDB_G0290635%3C%2Fa%3E 
chr3	6151208	6152251	-	DDB_G0282699	DDB_G0282699	NA
chr3	6152994	6154040	-	DDB_G0282701	DDB_G0282701	NA
chr3	6156398	6156934	-	DDB_G0282703	DDB_G0282703_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr3	6158594	6159045	-	DDB_G0282705	DDB_G0282705	NA
chr3	6160620	6164193	-	DDB_G0282707	DDB_G0282707	NA
chr3	6165937	6169517	-	DDB_G0282809	DDB_G0282809_ps	putative pseudogene%3B similar to EGF repeat-containg proteins such as %3Ca href%3D%22%2Fgene%2FDDB_G0290841%22%3EDDB_G0290841%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0293664%22%3EDDB_G0293664%3C%2Fa%3E
chr3	6170766	6179193	+	DDB_G0282375	amiB	novel protein required for aggregation%3B putative poorly conserved ortholog of the mediator of RNA polymerase II transcription subunit 13
chr3	6179495	6183789	-	DDB_G0282711	DDB_G0282711	contains a plant homeodomain (PHD) finger%2C a C4HC3 zinc-finger-like motif found in nuclear proteins thought to be involved in chromatin-mediated transcriptional regulation
chr3	6187048	6189000	+	DDB_G0282811	gtaK	has 18 amino acids between the two CX2C motifs
chr3	6189456	6191092	+	DDB_G0282713	DDB_G0282713	similar to D. purpureum protein
chr3	6191274	6194070	-	DDB_G0282715	DDB_G0282715	NA
chr3	6195317	6198952	+	DDB_G0282717	gxcAA	NA
chr3	6199706	6201021	+	DDB_G0282719	DDB_G0282719	NA
chr3	6201456	6202916	+	DDB_G0282721	DDB_G0282721	NA
chr3	6203669	6205412	+	DDB_G0282723	tmem104	integral membrane protein that is involved in the transport of amino acids into the cell%3B contains 10 putative transmembrane domains and an additional signal sequence
chr3	6207123	6212648	-	DDB_G0282725	vilD	belongs to the villin%2Fgelsolin family%3B contains 7 gelsolin-like repeats and one villin headpiece domain
chr3	6213878	6215173	-	DDB_G0282727	mcfU	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr3	6215725	6219713	+	DDB_G0282729	DDB_G0282729	NA
chr3	6220731	6222999	+	DDB_G0282731	polA2	ortholog of the B subunit of the DNA polymerase alpha-primase complex%2C required for the initiation of DNA replication
chr3	6225357	6226211	+	DDB_G0282737	DDB_G0282737	member of a Dictyostelium protein family that includes %3Ca href%3D%22%2Fgene%2FDDB_G0287587%22%3E%3Ci%3EsmlA%3C%2Fi%3E%3C%2Fa%3E%2C which is expressed in vegetative and early developing cells and is involved in aggregate formation
chr3	6226742	6227440	-	DDB_G0282739	rpb4	component of the RNA polymerase II complex%3B ortholog of S. cerevisiae RPB4
chr3	6230156	6232041	-	DDB_G0282741	ddx18	ortholog of H. sapiens DDX18 and S. cerevisiae HAS1 (Helicase Associated with Set1)
chr3	6232657	6233325	+	DDB_G0282743	haao	catalyzes the reaction 3-hydroxyanthranilate %2B O%3Csub%3E2%3C%2Fsub%3E %3D 2-amino-3-carboxymuconate semialdehyde
chr3	6234797	6237354	-	DDB_G0282745	DDB_G0282745	NA
chr3	6239552	6240857	+	DDB_G0282747	DDB_G0282747	similar to H. sapiens MAD2L2%2C a second protein in higher eukaryotes similar to S. cerevisiae MAD2
chr3	6241172	6242290	-	DDB_G0282749	bzpG	NA
chr3	6243320	6247805	-	DDB_G0282381	gefC	NA
chr3	6249781	6254932	+	DDB_G0282895	DDB_G0282895	member of the TKL (tyrosine kinase-like) group%3B contains three N-terminal MORN (Membrane Occupation and Recognition Nexus) repeats
chr3	6255151	6255351	-	DDB_G0282821	DDB_G0282821	NA
chr3	6256774	6256941	+	DDB_G0282897	tom7	homologous to mitochondrial import protein 7 kDa subunit%3B associates with TOM40 in yeast
chr3	6258530	6259384	-	DDB_G0282815	DDB_G0282815	similar to smlA
chr3	6262357	6265680	-	DDB_G0282823	DDB_G0282823	contains 6 TPR repeat regions
chr3	6266209	6267258	-	DDB_G0282825	yipf6	very similar to Yip1 domain family member 6 (YIPF6)%3B in yeast%2C YIP1 localizes to the Golgi and interacts with GTPases%3B contains five putative transmembrane domains
chr3	6268123	6269778	-	DDB_G0282827	DDB_G0282827	NA
chr3	6270236	6270887	-	DDB_G0282829	gxcAA_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0282717%22%3E%3Ci%3EgxcAA%3C%2Fi%3E%3C%2Fa%3E
chr3	6271490	6272740	+	DDB_G0282813	arcB	34 kDa component of the Dictyostelium Arp2%2FArp3 complex%3Cbr%2F%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with arpE (actin related protein 5) 
chr3	6273125	6273518	+	DDB_G0282831	pcbd	catalyzes the dehydration of 4a-hydroxytetrahydrobiopterins%3B might function in both as transcriptional coactivator and as pterin dehydratase%3B similar to H. sapiens PCBD1 and PCBD2
chr3	6273796	6274752	-	DDB_G0282833	DDB_G0282833	NA
chr3	6278818	6280318	+	DDB_G0282835	srfB	NA
chr3	6281058	6281939	+	DDB_G0282899	rabV	NA
chr3	6282388	6283681	+	DDB_G0282839	DDB_G0282839	NA
chr3	6284231	6285925	-	DDB_G0282841	DDB_G0282841	NA
chr3	6287418	6288822	+	DDB_G0282843	DDB_G0282843	NA
chr3	6289243	6290713	-	DDB_G0282845	DDB_G0282845	NA
chr3	6292039	6292775	+	DDB_G0282847	rab5B	similar to rab5%2C but has a long amino extension and is missing two conserved cysteine residues at the carboxyl terminus
chr3	6293427	6296760	-	DDB_G0282849	DDB_G0282849	NA
chr3	6297857	6302094	+	DDB_G0282851	cepL	ortholog of the human CDK5 regulatory subunit-associated protein 2 (CDK5RAP2)%3B in %3Ci%3EDictyostelium%3C%2Fi%3E%2C localizes to the centrosome and is involved in growth and development.
chr3	6303739	6304648	+	DDB_G0282853	DDB_G0282853	similar to mammalian translationally controlled tumour protein (TCTP) and to S. cerevisiae TMA19%2C a protein associated with ribosomes
chr3	6304937	6307397	+	DDB_G0282855	DDB_G0282855	NA
chr3	6309404	6312689	+	DDB_G0282817	patB	plasma membrane P-type H%3Csup%3E%2B%3C%2Fsup%3E-ATPase that is necessary for survival in acidic environments
chr3	6314029	6315501	-	DDB_G0282857	DDB_G0282857	NA
chr3	6316518	6318407	+	DDB_G0282859	DDB_G0282859	NA
chr3	6318668	6319252	-	DDB_G0282861	DDB_G0282861	similar to mammalian translationally controlled tumour protein (TCTP) and to S. cerevisiae TMA19%2C a protein associated with ribosomes
chr3	6319736	6320163	-	DDB_G0282863	snrpG	NA
chr3	6320360	6321049	-	DDB_G0282865	DDB_G0282865	NA
chr3	6322173	6323255	-	DDB_G0282867	DDB_G0282867	NA
chr3	6323600	6325343	-	DDB_G0282869	sslA_ps1	putative pseudogene%3B almost identical to sslA
chr3	6325570	6328516	-	DDB_G0282873	DDB_G0282873	similar to human cleavage and polyadenylation specific factor 6 (CPSF6)
chr3	6329217	6329945	+	DDB_G0282875	DDB_G0282875	NA
chr3	6330480	6331421	+	DDB_G0282877	DDB_G0282877	NA
chr3	6331837	6332697	-	DDB_G0282879	DDB_G0282879	NA
chr3	6333061	6334356	+	DDB_G0282881	DDB_G0282881	NA
chr3	6334464	6335236	-	DDB_G0282901	DDB_G0282901	NA
chr3	6335773	6337539	+	DDB_G0282819	sglA	null mutant is 25-fold more resistant to cisplatin compared to parent%3B catalyzes the reaction sphinganine 1-phosphate %3C%3D%3E phosphoethanolamine %2B palmitaldehyde
chr3	6337930	6339130	+	DDB_G0282883	DDB_G0282883	NA
chr3	6339466	6340840	+	DDB_G0282885	DDB_G0282885	NA
chr3	6341041	6341809	-	DDB_G0282887	trappc2	conserved trafficking protein particle (TRAPP) complex subunit
chr3	6342424	6344481	+	DDB_G0282903	DDB_G0282903	similar to a D. purpureum gene%3B contains 7 transmembrane domains
chr3	6346144	6349794	+	DDB_G0282891	pakG	putative protein serine%2Fthreonine kinase%3B belongs to the protein kinase PAKL subfamily%3B the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B stress-responsive kinase
chr3	6349872	6351423	+	DDB_G0282893	DDB_G0282893	contains two predicted transmembrane domains%2C the first may be a signal peptide%3B almost identical to the downstream gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0282905%22%3EDDB_G0282905%3C%2Fa%3E
chr3	6351923	6353597	+	DDB_G0282905	DDB_G0282905	contains one predicted transmembrane domain%3B almost identical to the upstream gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0282893%22%3EDDB_G0282893%3C%2Fa%3E
chr3	6356405	6356941	+	DDB_G0282907	DDB_G0282907_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr3F	1564	3538	+	DDB_G0294320	DDB_G0294320_RTE	long terminal repeat retrotransposon Skipper GAG-PRO-POL%3B refer to GenBank AF049230 for full length consensus element
chr3F	3594	3995	+	DDB_G0294322	DDB_G0294322_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr3F	4168	4887	-	DDB_G0294324	DDB_G0294324_RTE	ORF1 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr3F	5068	5738	-	DDB_G0294326	DDB_G0294326_TE	ORF2 (contains 2 introns) encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr3F	6019	6912	-	DDB_G0294328	DDB_G0294328_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr3F	7990	8707	-	DDB_G0294332	DDB_G0294332_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr3F	10123	11422	-	DDB_G0294336	DDB_G0294336_RTE	Partial ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr3F	11485	13805	-	DDB_G0294338	DDB_G0294338_RTE	Partial ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr3F	16145	16660	+	DDB_G0294340	DDB_G0294340_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr4	101	993	+	DDB_G0282919	DDB_G0282919_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr4	3257	3631	-	DDB_G0282917	DDB_G0282917	NA
chr4	9046	11927	-	DDB_G0282931	abcB6	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr4	12867	15427	+	DDB_G0282933	mcm7	similar to MCM7%2C a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
chr4	15565	16751	-	DDB_G0283053	fntA	catalyzes the transfer of a farnesyl group or a geranylgeranyl group via a thioether linkage (-C-S-C-) to a cysteine at or near the carboxyl terminus of the protein%3B forms a heterodimer with the %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270948%22%3E%3Ci%3Ebeta%3C%2Fi%3E%3C%2Fa%3E subunit
chr4	17607	19058	-	DDB_G0282935	DDB_G0282935	contains two putative transmembrane domains%3B partial high similarity to D. purpureum protein
chr4	19492	20019	-	DDB_G0282937	DDB_G0282937	contains a possible signal peptide
chr4	20488	22100	+	DDB_G0283055	DDB_G0283055	very similar to the mammalian TBC1 domain family member 20 protein%2C a potential multi-pass membrane protein
chr4	22195	23766	-	DDB_G0282939	DDB_G0282939	NA
chr4	24418	26871	+	DDB_G0282941	DDB_G0282941	NA
chr4	28010	31415	+	DDB_G0282943	DDB_G0282943	NA
chr4	31559	33775	-	DDB_G0282945	DDB_G0282945	NA
chr4	34226	37566	-	DDB_G0283057	DDB_G0283057	similar to H. sapiens Rap1GAP
chr4	38803	42072	-	DDB_G0282947	DDB_G0282947	NA
chr4	42516	44512	-	DDB_G0282949	elmoC	NA
chr4	45329	45825	+	DDB_G0282951	DDB_G0282951	contains a putative N-terminal signal peptide
chr4	45934	47981	-	DDB_G0282953	DDB_G0282953	family member of conserved eukaryotic proteins of unknown function%3B contains the conserved DUF1671 domain
chr4	49492	50609	+	DDB_G0282955	DDB_G0282955	NA
chr4	50957	51163	-	DDB_G0282957	DDB_G0282957	NA
chr4	52235	56945	+	DDB_G0282959	DDB_G0282959	contains 8 transmembrane domains
chr4	57054	58860	-	DDB_G0282961	DDB_G0282961	NA
chr4	59280	59392	+	DDB_G0295561	sno15	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr4	60445	65808	+	DDB_G0282963	DDB_G0282963	member of the TKL (tyrosine kinase-like) group%3B belongs to the ARK (ankyrin repeat-containing kinase) family%2C although it does not contain ankyrin repeats
chr4	67134	67898	+	DDB_G0282923	rdeA	component of a multistep phosphorelay modulating the rate of development
chr4	68065	69168	-	DDB_G0282965	DDB_G0282965	NA
chr4	69391	70422	-	DDB_G0283061	DDB_G0283061	similar to human PUSL1 which catalyzes the isomerization of tRNA uridine to tRNA pseudouridine
chr4	70875	72116	+	DDB_G0282967	acadsb	mammalian ACADSB has highest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA%2C isobutyryl-CoA%2C and 2-methylhexanoyl-CoA as well as toward short straight chain butyryl-CoA and hexanoyl-CoA%3B in human%2C defects in ACADSB cause short%2Fbranched-chain acyl-CoA dehydrogenase deficiency (SBCADD)%2C also called 2-methylbutyryl-CoA dehydrogenase deficiency or 2-methylbutyryl glycinuria
chr4	72206	73834	-	DDB_G0282969	masB	catalyzes the reaction acetyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO %2B glyoxylate %3C%3D%3E malate %2B coenzyme A
chr4	74287	76772	+	DDB_G0282971	DDB_G0282971	NA
chr4	77659	77701	-	DDB_G0295563	r48	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	78185	79172	+	DDB_G0282973	stpA	NA
chr4	80707	81807	+	DDB_G0282975	DDB_G0282975	NA
chr4	81934	85011	-	DDB_G0282977	DDB_G0282977	NA
chr4	86151	88130	+	DDB_G0294621	DDB_G0294621	contains three Sel1-like repeats%2C which are related to tetratricopeptide (TPR) repeats 
chr4	88701	90098	+	DDB_G0282979	efa1G	component of the eukaryotic translation elongation factor EF-1%2C which plays a role in attaching aminoacyl-tRNAs to the ribosome
chr4	90982	98705	+	DDB_G0282925	lvsE	similar to human LYST and mouse Beige proteins
chr4	98815	99650	-	DDB_G0282981	tgrI_ps2	putative pseudogene%3B immunoglobulin E-set family gene
chr4	99975	101720	+	DDB_G0282983	DDB_G0282983	contains an N-terminal F-box domain
chr4	102023	104770	-	DDB_G0282985	DDB_G0282985	NA
chr4	105576	106310	+	DDB_G0282987	hcpB	contains two Chromo domains%3B locates to the centromere and plays a role in growth%3B forms a homodimer or a heterodimer with hcpA
chr4	107175	108589	+	DDB_G0282989	fscB	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr4	109030	110049	+	DDB_G0282991	DDB_G0282991	NA
chr4	110200	111541	-	DDB_G0282993	sodC	GPI-anchored plasma membrane superoxide dismutase%3B  upregulated upon oxidative stress%3B mutants have defects in cytokinesis%2C chemotaxis%2C and localization of several protein during aggregation
chr4	113431	114507	+	DDB_G0282995	DDB_G0282995	NA
chr4	115315	116295	-	DDB_G0283063	DDB_G0283063	NA
chr4	118731	121607	+	DDB_G0282997	rad54	similar to RAD54 DNA repair protein%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr4	122741	124654	-	DDB_G0283065	DDB_G0283065	putative eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase%3B putative protein serine%2Fthreonine kinase%3B related to the GCN2 (general control non-derepressible) family of protein kinases that phosphorylate the alpha subunit of eIF2
chr4	127874	133086	+	DDB_G0282927	dhkL	NA
chr4	133295	135115	-	DDB_G0282999	maoD	catalyzes the reaction RCH%3Csub%3E2%3C%2Fsub%3ENH%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3D RCHO %2B ammonia %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3B acts on primary amines%2C as well as on some secondary and tertiary amines
chr4	138075	139277	+	DDB_G0283067	DDB_G0283067	NA
chr4	139924	140950	-	DDB_G0283001	bloc1s7	ortholog of human SNAPIN%2FBLOC1S7%2C a component of the BLOC-1 complex that is required for normal biogenesis of lysosome-related organelles
chr4	141272	141856	+	DDB_G0283003	DDB_G0283003	NA
chr4	142399	143635	+	DDB_G0283049	immp	in other organisms%2C there are two subunits for this enzyme%2C with relatively high sequence similarity to each other%3B Dictyostelium appear to have a single gene
chr4	143819	145984	-	DDB_G0283005	agtA	likely catalyzes the alpha addition of galactose to Fuc-Gal-GlcNAc-HyPro143-Skp1 (FpaA%2FFpaB)
chr4	147313	148900	+	DDB_G0283007	DDB_G0283007	NA
chr4	149067	151575	-	DDB_G0283009	mcm8	similar to H. sapiens MCM8
chr4	151994	152491	-	DDB_G0283011	DDB_G0283011	contains a weak t-SNARE coiled-coil region which corresponds to one putative transmembrane domain
chr4	153182	160521	+	DDB_G0283013	DDB_G0283013	NA
chr4	160759	161341	-	DDB_G0282929	atg12	Dictyostelium homolog of yeast atg12
chr4	161759	163598	-	DDB_G0283015	DDB_G0283015	contains 2 putative transmembrane domains%3B contains one putative coiled-coil domain
chr4	164286	166961	+	DDB_G0283017	DDB_G0283017	NA
chr4	167136	167543	-	DDB_G0283019	DDB_G0283019	contains two breast cancer type 2 repeats%3B BRCA2 is a breast tumor suppressor with a potential function in the cellular response to DNA damage
chr4	167774	169139	-	DDB_G0283021	sodB	upregulated upon oxidative stress
chr4	170065	170742	-	DDB_G0283023	hcpA	contains two Chromo domains%3B locates to the centromere and plays a role in growth and mitosis%3B forms a heterodimer with hcpB
chr4	171885	174319	-	DDB_G0283025	DDB_G0283025_ps	putative pseudogene%3B immunoglobulin E-set family gene
chr4	174707	174977	-	DDB_G0283027	tgrT_ps2	putative pseudogene%3B immunoglobulin E-set family gene
chr4	175065	175606	+	DDB_G0283069	DDB_G0283069	NA
chr4	175761	176462	-	DDB_G0283029	tgrT_ps1	putative pseudogene%3B immunoglobulin E-set family gene
chr4	177075	178241	+	DDB_G0283031	DDB_G0283031	NA
chr4	178285	180683	-	DDB_G0283033	DDB_G0283033	NA
chr4	181322	181939	+	DDB_G0283071	DDB_G0283071	NA
chr4	182130	184025	-	DDB_G0283073	orcA	DNA replication initiation is driven by a conserved six protein complex%2C the origin recognition complex (ORC)%3B has a role in both chromosomal replication and mating type transcriptional silencing
chr4	184491	186870	-	DDB_G0283035	osbG	NA
chr4	188331	190020	-	DDB_G0283075	DDB_G0283075	ortholog of mammalian MORF4 and S. cerevisiae EAF3%2C a nonessential component of the NuA4 acetyltransferase complex 
chr4	190346	191610	-	DDB_G0282921	ctu1	ortholog of S. pombe ctu1 (cytosolic thiouridylase subunit 1)%3B with ctu2%2C required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs
chr4	192516	193525	+	DDB_G0283037	esd	very similar to human ESD and to S. cerevisiae S-formylglutathione hydrolase (YJL068C)%2C which seems to be involved in formaldehyde detoxification
chr4	194597	196524	+	DDB_G0283077	DDB_G0283077	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages
chr4	196663	198359	-	DDB_G0283039	DDB_G0283039	NA
chr4	198610	199358	-	DDB_G0283041	DDB_G0283041	NA
chr4	199920	201972	-	DDB_G0283079	DDB_G0283079_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr4	203029	204917	+	DDB_G0283087	DDB_G0283087	similar to butyrylcholinesterase and acetylcholinesterase precursor proteins%3B contains a putative signal peptide
chr4	205098	206531	-	DDB_G0283089	DDB_G0283089	NA
chr4	206705	208093	-	DDB_G0283091	DDB_G0283091	NA
chr4	208398	209741	-	DDB_G0283093	DDB_G0283093	NA
chr4	210212	212062	-	DDB_G0283095	DD3-3	similar to tunicate proteins%3B involved in O-glycosylation as identified by mRNA differential display
chr4	214573	215986	+	DDB_G0283097	DDB_G0283097	NA
chr4	217095	223472	+	DDB_G0283099	DDB_G0283099	ortholog of the metazoan nipped-B protein%2C which contains the armadillo-like (ARM-like) helical domain and two HEAT repeats%3B the %3Ci%3EDrosophila%3C%2Fi%3E protein plays a structural role in chromatin and is involved in sister chromatid cohesion
chr4	223712	224049	-	DDB_G0283135	DDB_G0283135	NA
chr4	225309	226956	-	DDB_G0283137	enoA	catalyzes the reaction 2-phospho-D-glycerate %3C%3D%3E phosphoenolpyruvate %2B H%3Csub%3E2%3C%2Fsub%3EO%3B enriched in gametes
chr4	228583	231752	-	DDB_G0283139	DDB_G0283139	mannose-6-phosphate receptors are involved in the transport of lysosomal enzymes from the Golgi complex and the cell surface to lysosomes%3B contains a N-terminal predicted signal sequence and a C-terminal transmembrane domain
chr4	232444	234737	-	DDB_G0283133	DDB_G0283133_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr4	235690	236349	+	DDB_G0283101	DDB_G0283101	NA
chr4	237163	238605	-	DDB_G0283103	DDB_G0283103	NA
chr4	241054	242480	-	DDB_G0349073	DDB_G0349073_ps	putative pseudogene%3B fragment%2C similar to a D. discoideum gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290349%22%3EDDB_G0290349%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290285%22%3EDDB_G0290285%3C%2Fa%3E
chr4	243331	246513	-	DDB_G0283143	DDB_G0283143	NA
chr4	247398	252971	-	DDB_G0283081	pikB	NA
chr4	254487	255258	-	DDB_G0283145	DDB_G0283145	NA
chr4	255521	256804	-	DDB_G0283107	DDB_G0283107	NA
chr4	257953	261035	+	DDB_G0283109	iksA	similar to fungal kinases%3B contains an IQ calmodulin-binding region
chr4	261195	263277	-	DDB_G0283111	cepD	localizes to the centrosomal core structure  
chr4	263707	264369	+	DDB_G0283113	eriA	similar to %3Ci%3EC. elegans%3C%2Fi%3E eri-1%2C RNA exonuclease that acts as a negative regulator of RNA interference (RNAi)%3B contains one exonuclease domain%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E EriA codes for a multifunctional RNA exonuclease which has been identified with negative regulation of RNAi and in processing the 5.8s ribosomal RNA. The gene is nearly 8-fold overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA is disrupted. Other genes overexpressed in this strain include virtually all those with unique or major functions in S-phase or mitosis. Neither RNAi nor ribosomal processing obviously fits into this class. However%2C it has recently been shown in mammalian cells that eriA%2C under the pseudonym 3%27hExo%2C stably associates with histone pre-mRNAs%2C and participates in a complex that determines the site of their cleavage (see Yang et al%2C Mol Cell Biol 29%2C 4045-4056 (2009). Another protein in this complex is the histone stem-loop binding protein DDB_G0277383%2C which is threefold upregulated in the rblA mutant. The high overexpression factor of EriA%2C comparable to that of replication-specific DNA polymerases%2C suggests that this may be the main function of this gene in Dictyostelium. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E
chr4	264436	266640	-	DDB_G0283115	cnrB	identified as a suppressor of smlA null mutant cnr2%3B contains six predicted transmembrane domains
chr4	267048	268356	-	DDB_G0283117	DDB_G0283117	NA
chr4	269911	273800	-	DDB_G0283119	xpot	ortholog of H. sapiens XPOT involved in the export of aminoacylated tRNAs from the nucleus
chr4	275079	276215	+	DDB_G0283121	DDB_G0283121	bifunctional enzyme that catalyzes the reactions methylene-tetrahydrofolate %2B NADP %3C%3D%3E NADPH %2B methenyl-H%3Csub%3E4%3C%2Fsub%3EF and NADPH %2B methenyl-H%3Csub%3E4%3C%2Fsub%3EF %3C%3D%3E methylene-tetrahydrofolate %2B NADP
chr4	276713	278420	+	DDB_G0283085	D2	contains a predicted signal peptide
chr4	279175	279959	-	DDB_G0283083	cbpD2	contains four EF-hands%3B expressed in post-aggregation stage of development
chr4	281753	283546	+	DDB_G0283125	uduD2	upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant%3B almost identical to %3Ca href%3D%22%2Fgene%2FDDB_G0277083%22%3E%3Ci%3EuduD1%3C%2Fi%3E%3C%2Fa%3E
chr4	283814	285345	-	DDB_G0283127	DDB_G0283127	NA
chr4	286809	289740	+	DDB_G0283129	DDB_G0283129	NA
chr4	290287	290668	+	DDB_G0283131	cmbC_ps1	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0269116%22%3E%3Ci%3EcmbC%3C%2Fi%3E%3C%2Fa%3E 
chr4	291263	295035	-	DDB_G0283147	DDB_G0283147	NA
chr4	295136	296249	-	DDB_G0283259	DDB_G0283259	NA
chr4	297464	298660	+	DDB_G0283155	DDB_G0283155	NA
chr4	299093	300864	-	DDB_G0283157	ppp5C	NA
chr4	301718	303846	+	DDB_G0283159	DDB_G0283159	NA
chr4	303938	304342	-	DDB_G0283161	DDB_G0283161	NA
chr4	306164	307384	-	DDB_G0283151	gpaF	subunit of the heterotrimeric G protein that has GTPase activity
chr4	309059	310909	-	DDB_G0283213	DDB_G0283213	NA
chr4	311593	313110	+	DDB_G0283215	DDB_G0283215	NA
chr4	313913	315895	+	DDB_G0283217	DDB_G0283217_ps	putative pseudogene%3B similar to a family of Dictyostelium putative mannose-6-phosphate receptors%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0283139%22%3EDDB_G0283139 %3C%2Fa%3E
chr4	316554	316930	-	DDB_G0283219	DDB_G0283219_ps	putative pseudogene%3B fusion fragment similar to parts of %3Ca href%3D%22%2Fgene%2FDDB_G0295757%22%3EDDB_G0295757%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0280195%22%3EhdaC%3C%2Fa%3E
chr4	317030	317365	-	DDB_G0283221	DDB_G0283221_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0293070%22%3EDDB_G0293070%3C%2Fa%3E
chr4	318683	319227	+	DDB_G0283223	DDB_G0283223_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0293070%22%3EDDB_G0293070%3C%2Fa%3E
chr4	319419	322601	-	DDB_G0283227	DDB_G0283227	NA
chr4	324812	327990	-	DDB_G0283229	DDB_G0283229	NA
chr4	329911	330651	-	DDB_G0283231	DDB_G0283231	NA
chr4	331060	334220	+	DDB_G0283233	DDB_G0283233_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0283227%22%3EDDB_G0283227%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283243%22%3EDDB_G0283243%3C%2Fa%3E
chr4	335133	335680	-	DDB_G0283235	DDB_G0283235_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0283241%22%3EDDB_G0283241%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283101%22%3EDDB_G0283101%3C%2Fa%3E
chr4	336082	338328	+	DDB_G0283237	DDB_G0283237_ps	putative pseudogene%3B similar to a family of Dictyostelium genes including %3Ca href%3D%22%2Fgene%2FDDB_G0283227%22%3EDDB_G0283227%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283243%22%3EDDB_G0283243%3C%2Fa%3E
chr4	338450	339091	-	DDB_G0283241	DDB_G0283241	NA
chr4	339770	342966	+	DDB_G0283243	DDB_G0283243	NA
chr4	343211	343819	-	DDB_G0283245	DDB_G0283245	contains a putative N-terminal signal sequence and a C-terminal transmembrane domain
chr4	344914	346711	-	DDB_G0283247	pyk	catalyzes the reaction ATP %2B pyruvate %3C%3D%3E ADP %2B phosphoenolpyruvate
chr4	347658	348447	-	DDB_G0283153	cbpD1	contains four EF-hands%3B expressed in post-aggregation stage of development
chr4	349612	351949	-	DDB_G0283163	eif2b5	EIF2B5 ortholog%2C the eukaryotic initiation factor 2B epsilon subunit%3B guanyl nucleotide exchange factor for eIF2%3B defects are linked to leukoencephalopathy with vanishing white matter
chr4	352482	354212	-	DDB_G0283165	samkE_ps1	putative pseudogene%3B SAMK (SAM domain-containing kinase) family
chr4	356370	357076	+	DDB_G0283169	DDB_G0283169	NA
chr4	358763	359168	+	DDB_G0283171	DDB_G0283171	NA
chr4	359274	360656	-	DDB_G0283173	kmo	catalyzes the reaction L-kynurenine %2B NADPH %2B H%2B %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E 3-hydroxy-L-kynurenine %2B NADP%2B %2B H%3Csub%3E2%3C%2Fsub%3EO during nicotinic acid biosynthesis
chr4	360952	362348	+	DDB_G0283175	prfA	required for the termination of protein biosynthesis%3B class I release factors bind to ribosomes that have encountered a stop codon at their decoding site and induce release of the nascent polypeptide%3B mediates UAA and UAG-dependent termination in prokaryotes
chr4	362729	364548	+	DDB_G0283177	DDB_G0283177	NA
chr4	364837	365001	-	DDB_G0283209	DDB_G0283209	NA
chr4	366668	366883	-	DDB_G0283179	DDB_G0283179	NA
chr4	368141	369137	-	DDB_G0283211	DDB_G0283211_ps	putative pseudogene%2C belongs to the large D. discoideum zinc-containing alcohol dehydrogenase (ADH) family
chr4	370291	372918	-	DDB_G0283249	tgrI3	NA
chr4	373477	375261	+	DDB_G0283183	tgrH_ps2	putative pseudogene%3B immunoglobulin E-set family gene
chr4	376419	377762	+	DDB_G0283185	DDB_G0283185	NA
chr4	377937	380372	-	DDB_G0283251	DDB_G0283251	NA
chr4	381819	383085	+	DDB_G0283187	DDB_G0283187	catalyzes the reaction: A phosphoprotein %2B H%3Csub%3E2%3C%2Fsub%3EO %3D a protein %2B phosphate%3B conserved serine%2Fthreonine protein phosphatase family protein
chr4	383852	384293	-	DDB_G0283253	DDB_G0283253	NA
chr4	385928	393596	-	DDB_G0283189	DDB_G0283189	similar to DNA polymerase epsilon subunit A in yeast and vertebrates%3B thought to be involved in DNA replication%2C DNA repair%2C and cell-cycle checkpoint control in eukaryotes
chr4	394762	396456	+	DDB_G0283191	DDB_G0283191	NA
chr4	396519	397589	-	DDB_G0283193	DDB_G0283193	NA
chr4	398240	399952	+	DDB_G0283255	DDB_G0283255	NA
chr4	400645	403732	+	DDB_G0283195	DDB_G0283195	NA
chr4	404751	405456	+	DDB_G0283257	samkE_ps2	putative pseudogene%3B SAMK (SAM domain-containing kinase) family%3B does not contain the consensus sequences required for kinase function
chr4	407180	409147	+	DDB_G0283197	DDB_G0283197	NA
chr4	409273	410244	-	DDB_G0283199	DDB_G0283199	NA
chr4	411746	413523	+	DDB_G0283149	cotD	NA
chr4	413865	414903	+	DDB_G0283201	DDB_G0283201	contains two tandem C2H2-type zinc finger domains
chr4	415279	416235	+	DDB_G0283203	vps22	component of the ELL complex%2C an RNA polymerase II transcription factor%2C and of the ESCRT-II complex (endosomal sorting complex required for transport)
chr4	416900	419809	+	DDB_G0283205	top1	ortholog of TOP1%2C a nuclear topoisomerase responsible for relaxing single-stranded supercoiled DNA
chr4	424767	428726	+	DDB_G0283325	DDB_G0283325	NA
chr4	428924	430693	-	DDB_G0283269	DDB_G0283269	has similarity to mammalian threonine aspartase 1%2C which belongs to the asparaginase 2 family
chr4	431083	432443	+	DDB_G0283327	eppA	putative substrate for erkB%3B highly repetitive protein%3B contains a possible eggshell domain%2C first identified in the human parasite Schistosome mansoni
chr4	432962	435476	-	DDB_G0283329	mcfO	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3B very similar to the calcium-dependent mitochondrial aspartate and glutamate carrier aralar1 (slc25A12)%3B the human protein may have a function in the urea cycle%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr4	436406	437655	-	DDB_G0283271	DDB_G0283271	contains an N-terminal DOMON domain as it occurs in dopamine beta-monooxygenases%3B the %3Ci%3EDictyostelium%3C%2Fi%3E protein is followed by a cytochrome b561 domain%2C which contains 5 putative transmembrane regions%3B in addition%2C the protein contains a putative signal peptide
chr4	438511	441126	+	DDB_G0283267	shkA	member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily%3B contains a C-terminal SH2 (Src homology 2) domain%3B negative regulator of phosphoinositol signaling
chr4	441777	442542	-	DDB_G0283273	mrpl51	homolog of S. cerevisiae MRPL51%3B protein component of the mitochondrial large ribosomal subunit
chr4	442808	443794	+	DDB_G0283275	DDB_G0283275	similar to bacterial 50S ribosomal L4%2FL1e proteins
chr4	443932	445571	-	DDB_G0283277	DDB_G0283277_ps	putative pseudogene%3B similar to CAZy family GH9%2C which catalyzes the hydrolysis of glucosidic linkages
chr4	446640	447716	-	DDB_G0283279	cdk11	very similar to human CDL1 (PITSLRE serine%2Fthreonine-protein kinase CDC2L1)%2C which appears to play multiple roles in cell cycle progression%2C cytokinesis and apoptosis%3B predicted to interact with %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2F%2Fgene_page.pl?gene_name%3DcycL%22%3Ecyclin L%3C%2Fa%3E
chr4	447879	449138	-	DDB_G0283281	DDB_G0283281	catalyzes the reaction tryptamine %2B secologanin %3D 3-alpha(S)-strictosidine %2B H%3Csub%3E2%3C%2Fsub%3EO in alkaloid biosynthesis
chr4	449907	452098	+	DDB_G0283261	acoA	catalyzes the reaction acyl-CoA %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E trans-2%2C3-dehydroacyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with aco%2C the oxidoreductase%2C or aco1 and aco2%2C the aconitases
chr4	453096	455785	+	DDB_G0283263	migA	NA
chr4	456147	457641	+	DDB_G0283283	atp5O	NA
chr4	458537	462904	+	DDB_G0283285	DDB_G0283285	NA
chr4	463265	464749	+	DDB_G0283287	fut7	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr4	465144	467321	+	DDB_G0283289	DDB_G0283289	NA
chr4	467526	468617	-	DDB_G0283291	DDB_G0283291	NA
chr4	469001	470093	-	DDB_G0283333	ucpB	ortholog of slc25a30%2C that belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane 
chr4	470714	471337	-	DDB_G0294593	DDB_G0294593	NA
chr4	472326	474925	+	DDB_G0283293	DDB_G0283293	catalyzes the reduction of glutamate to delta-1-pyrroline-5-carboxylate%2C a critical step in the de novo biosynthesis of proline and ornithine%3B expressed in pstO cells and in pstO cells and upper cup during culmination
chr4	476937	477164	+	DDB_G0283295	DDB_G0283295	NA
chr4	477747	478089	-	DDB_G0283299	tgrI_ps3	putative pseudogene%3B immunoglobulin E-set family gene
chr4	480042	482423	+	DDB_G0283301	DDB_G0283301	similar to many different classes of kinases
chr4	482981	486413	-	DDB_G0283323	tgrH1	NA
chr4	487136	489776	+	DDB_G0283335	tgrI1	NA
chr4	491931	495564	-	DDB_G0283337	DDB_G0283337	similar to mammalian FAK (focal adhesion kinase)
chr4	497204	498607	+	DDB_G0283303	DDB_G0283303	NA
chr4	498765	500435	-	DDB_G0283305	DDB_G0283305	contains a predicted signal sequence and a C-terminal transmembrane domain
chr4	501258	507721	-	DDB_G0283339	DDB_G0283339	NA
chr4	508620	510972	-	DDB_G0283307	prpf39	contains a putative HAT (Half A TPR) repeat%3B PRP39 in yeast is involved in mRNA splicing
chr4	511242	512282	-	DDB_G0283309	DDB_G0283309	similar to the eIF-2B alpha%2Fbeta%2Fdelta subunits family
chr4	512897	513361	+	DDB_G0283311	DDB_G0283311	NA
chr4	513450	514991	-	DDB_G0283313	DDB_G0283313	NA
chr4	515744	517800	+	DDB_G0283315	dcp2	ortholog of the conserved mRNA-decapping enzyme 2%2C necessary for the degradation of mRNAs
chr4	518010	521263	-	DDB_G0283341	tgrH_ps1	putative pseudogene%3B immunoglobulin E-set family gene
chr4	522108	524733	+	DDB_G0283317	tgrI2	NA
chr4	525048	527810	+	DDB_G0283319	ap4b1	putative ortholog of H. sapiens AP4B1%2C member of a complex that mediates protein sorting
chr4	527883	529745	-	DDB_G0283321	DDB_G0283321	NA
chr4	530684	534789	+	DDB_G0283265	mkkA	developmentally regulated MEKK%26alpha%3B kinase involved in cell-type differentiation and spatial patterning%3B contains an F-box followed by WD40 repeats
chr4	539820	543347	+	DDB_G0283345	comD	similar to drug resistance transporters%3B contains 14 transmembrane domains
chr4	543684	545458	-	DDB_G0283347	DDB_G0283347	NA
chr4	547836	549106	+	DDB_G0283349	gpaA	subunit of the heterotrimeric G protein that has GTPase activity
chr4	550541	555352	+	DDB_G0283351	DDB_G0283351	NA
chr4	556576	558318	+	DDB_G0283373	DDB_G0283373	contains a predicted signal peptide%3B contains one ERV%2FALR sulphydryl oxidase domain%3B similar to D. purpureum protein
chr4	558631	558804	+	DDB_G0283353	DDB_G0283353	NA
chr4	559359	563272	-	DDB_G0283355	swip	similar to human WASH complex subunit 7
chr4	564906	568727	+	DDB_G0283357	DDB_G0283357	NA
chr4	569125	572263	-	DDB_G0283359	eftud2	highly conserved U5 small nuclear ribonucleoprotein subunit that is similar to elongation factor Tu%3B ortholog of yeast SNU114 and human EFTUD2
chr4	572566	574122	+	DDB_G0283361	DDB_G0283361	NA
chr4	574408	576993	+	DDB_G0283375	coyA	similar to yeast COY1%2C human CCAAT displacement protein
chr4	578428	579892	+	DDB_G0283377	DDB_G0283377	NA
chr4	579956	583549	-	DDB_G0283379	DDB_G0283379	NA
chr4	584359	585348	+	DDB_G0283363	vti1B	similar to SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr4	585874	586210	+	DDB_G0283365	rpb12	subunit common to RNA polymerases I%2C II and III%3B ortholog of S. cerevisiae RPC10
chr4	586631	587125	-	DDB_G0283367	cofE	similar to cofA%2C a 15 kDa protein with actin filament severing activity%3B contains an actin-binding%2C cofilin%2Ftropomyosin type domain
chr4	587429	594000	-	DDB_G0283369	DDB_G0283369	NA
chr4	594665	600480	+	DDB_G0283381	DDB_G0283381	contains a weak Spc7 kinetochore protein domain%3B similar to %3Ci%3ED. purpureum%3C%2Fi%3E protein%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0283381 appears to be the ortholog of spc7 of Saccharomyces pombe and spc105 of Saccharomyces cerevesiae. Spc105 is a kinetochore component (see Pagliuca et al%2C Plos One 28%2C e7640m (2009)). Like the conserved kinetochore components spc25%2C nuf2 and ndc80%2C DDB_G0283381 is very strongly overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (spc25%2C 30-fold%3B nuf2%2C 18-fold%3B ndc80%2C 16-fold%3B DDB_G0283381%2C 29-fold) (Doquang et al%2C in preparation). This presumably reflects a cell cycle function%2C as most cell cycle genes are overexpressed in this strain%2C and most of the genes strongly overexpressed in the strain have identifiable cell cycle functions. Spc105 forms a complex with kre28%2C but I could not identify a corresponding gene in Dicty%2C even by using Ashbya as an intermediate. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0283381%22%3E There is more information on the wiki page%3C%2Fa%3E
chr4	600577	602174	-	DDB_G0283371	udkC	contains a N-terminal uridine kinase domaine domain and a C-terminal adenylate cyclase domain%2C like the UdkD protein and other plant proteins
chr4	603790	603964	-	DDB_G0283383	DDB_G0283383	NA
chr4	605068	605358	-	DDB_G0283493	DDB_G0283493	almost identical to neighboring gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283395%22%3E%3Ci%3EDDB_G0283395%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E 
chr4	606034	606316	-	DDB_G0283395	DDB_G0283395	almost identical to neighboring gene%2C %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283493%22%3E%3Ci%3EDDB_G0283493%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr4	606939	609695	-	DDB_G0283397	DDB_G0283397	member of the TKL (tyrosine kinase-like) group and the CZAK (C-terminal domain of ZakA) family
chr4	609993	610496	-	DDB_G0283399	DDB_G0283399	NA
chr4	611003	613564	+	DDB_G0283495	DDB_G0283495	NA
chr4	613897	615290	+	DDB_G0283401	ctsZ	member of the papain cysteine protease family%2C which has a wide range of specificities
chr4	615804	618044	+	DDB_G0283403	DDB_G0283403	NA
chr4	618312	619784	-	DDB_G0283405	bdp1	TFIIIB subunit%3B interacts with the non LTR retrotransposon TRE5-A%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Bdp1 is a subunit of TFIIIB%2C a factor necessary for the initiation of transcription by RNA polIII%2C and thus for the production of tRNA and several other small RNAs. TFIIIB is overexpressed in a wide variety of cancers%2C see White%2C Oncogene 23%2C 3208-3216 (2004). In healthy cells%2C TFIIIB interacts with and is inhibited by the tumor-suppressor Rb. Interestingly%2C bdp1 is overexpressed (threefold%3B p%3C6e-10) in a Dicty strain in which the rb-like gene rblA has been disrupted. The TFIIIB-Rb antagonism thus predates the development of organisms that have tumors. The function of this interaction remains to be explained. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E
chr4	620087	622845	+	DDB_G0283387	abcA10	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr4	623097	631896	+	DDB_G0283385	splA	dual-specificity protein kinase involved in spore coat formation and morphogenesis%3B member of the TKL (tyrosine kinase-like) group and the CZAK (C-terminal domain of ZakA) family
chr4	632298	633665	-	DDB_G0283407	DDB_G0283407	NA
chr4	634252	635927	-	DDB_G0283389	rhgA	similar to human Rh50 protein%2C a glycoprotein present on the surface of red blood cells%3B contains 10 transmembrane domains
chr4	637844	638400	-	DDB_G0283409	DDB_G0283409	NA
chr4	638800	640250	-	DDB_G0283411	gcdh	catalyzes the reaction glutaryl-CoA %2B acceptor %3C%3D%3E crotonoyl-CoA %2B CO%3Csub%3E2%3C%2Fsub%3E %2B reduced acceptor%3B belongs to the acyl-CoA dehydrogenase family
chr4	641115	643406	-	DDB_G0283485	DDB_G0283485	NA
chr4	648667	650194	-	DDB_G0283497	ssr1	subunit of the TRAP complex aids in the translocation of nascent polypeptides into the lumen of the endoplasmic reticulum
chr4	651190	652101	+	DDB_G0283413	DDB_G0283413	NA
chr4	652443	653317	-	DDB_G0283415	DDB_G0283415	NA
chr4	654013	654705	-	DDB_G0283417	DDB_G0283417	dual specificity phosphatases remove phosphate groups from tyrosine and serine%2Fthreonine residues 
chr4	656137	657400	-	DDB_G0283419	gpaI	NA
chr4	660137	660898	-	DDB_G0283499	DDB_G0283499	similar to a D. purpureum protein
chr4	661727	662322	-	DDB_G0283393	rplP2	NA
chr4	663424	663692	+	DDB_G0283421	DDB_G0283421	NA
chr4	665243	665515	+	DDB_G0283501	DDB_G0283501	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstAO cells
chr4	666044	666324	+	DDB_G0283503	DDB_G0283503	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstAO cells
chr4	666961	667221	+	DDB_G0283505	DDB_G0283505	contains one putative transmembrane domain%3B belongs to a family of small%2C highly conserved genes unique to Dictyostelium discoideum
chr4	667839	668095	+	DDB_G0283507	DDB_G0283507	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstAO cells
chr4	668710	668966	+	DDB_G0283509	DDB_G0283509	belongs to a family of small%2C highly conserved genes unique to Dictyostelium discoideum
chr4	669589	669845	+	DDB_G0283511	DDB_G0283511	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstAO cells and in upper and lower cups during culmination
chr4	670441	670695	+	DDB_G0283513	DDB_G0283513	belongs to a family of small%2C highly conserved genes unique to Dictyostelium discoideum
chr4	671329	671581	+	DDB_G0283515	DDB_G0283515	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstAO cells
chr4	672171	672430	+	DDB_G0283517	DDB_G0283517	NA
chr4	673055	673316	+	DDB_G0283519	DDB_G0283519	NA
chr4	673782	678359	+	DDB_G0283423	DDB_G0283423	NA
chr4	678402	682191	-	DDB_G0283521	DDB_G0283521	NA
chr4	683015	686483	-	DDB_G0283425	DDB_G0283425	NA
chr4	687466	687980	+	DDB_G0283427	DDB_G0283427	NA
chr4	688705	691281	+	DDB_G0283487	DDB_G0283487	NA
chr4	691392	692231	-	DDB_G0283429	DDB_G0283429	similar to proteins in bacteria and protozoa%3B COG4271%2C predicted nucleotide-binding protein containing TIR -like domain (Transcription)
chr4	692545	693098	-	DDB_G0283431	DDB_G0283431	NA
chr4	694005	695490	+	DDB_G0283433	DDB_G0283433_ps	putative pseudogene%3B similar to a large family of D. discoideum proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271418%22%3EDDB_G0271418%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271202%22%3EDDB_G0271202%3C%2Fa%3E
chr4	696044	696790	+	DDB_G0283435	DDB_G0283435	NA
chr4	697659	698518	+	DDB_G0283437	DDB_G0283437	similar to the Arabidopsis thaliana AMMECR1 family protein At2g38710
chr4	699253	700845	+	DDB_G0283439	DDB_G0283439	similar to H. sapiens solute carrier family 29%2C member 1 (SLC29A2)%3B putative ortholog of S. cerevisiae FUN2
chr4	701281	702009	+	DDB_G0283523	DDB_G0283523	conserved eukaryotic protein of unknown function
chr4	702819	705881	+	DDB_G0283441	abpG	contains an N-terminal calponin homology domain and two coiled-coil domains
chr4	706025	707206	-	DDB_G0283443	DDB_G0283443	NA
chr4	707432	708938	+	DDB_G0283445	DDB_G0283445	NA
chr4	709169	711416	+	DDB_G0283447	DDB_G0283447	NA
chr4	711483	711818	-	DDB_G0283449	DDB_G0283449	NA
chr4	712043	713824	-	DDB_G0283451	DDB_G0283451	NA
chr4	715640	717205	-	DDB_G0283453	dgcA	Dictyostelium diguanylate cyclase%2C synthesizes cyclic-di-GMP from 2 molecules of GTP%2C expressed at the slug and fruiting body tip%2C responsible for stalk differentiation
chr4	724620	725186	-	DDB_G0283455	DDB_G0283455	NA
chr4	726060	726872	-	DDB_G0283457	DDB_G0283457	NA
chr4	727119	728357	-	DDB_G0283459	gcn5	ortholog of S. cereviciae GCN5
chr4	729167	730191	+	DDB_G0283525	arl8	NA
chr4	731858	732052	+	DDB_G0283461	DDB_G0283461	NA
chr4	732951	733124	-	DDB_G0283527	DDB_G0283527	NA
chr4	733335	733606	+	DDB_G0283463	DDB_G0283463	NA
chr4	734816	735193	+	DDB_G0283465	DDB_G0283465	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstAO cells
chr4	735396	735856	-	DDB_G0283467	DDB_G0283467	NA
chr4	737091	737534	+	DDB_G0283469	DDB_G0283469	NA
chr4	738038	744476	-	DDB_G0283471	DDB_G0283471	NA
chr4	746464	748248	+	DDB_G0283473	treh	homolog of human TREH%3B catalyzes the reaction alpha%2Calpha-trehalose %2B H2O %3D 2 D-glucose%3B contains a predicted signal peptide
chr4	749416	752964	+	DDB_G0283391	kinX	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family%3B similar to LIM kinases which regulate actin dynamics
chr4	753547	760773	+	DDB_G0283475	DDB_G0283475	NA
chr4	760908	763256	-	DDB_G0283529	DDB_G0283529	NA
chr4	763555	766074	-	DDB_G0283477	DDB_G0283477	NA
chr4	766653	767474	+	DDB_G0283531	DDB_G0283531	NA
chr4	768532	771657	-	DDB_G0283479	abcH4	consists of one ABC domain and lacks a transmembrane domain
chr4	772790	774855	-	DDB_G0283481	DDB_G0283481	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and cfrA%2C B%2C C%2C and D (GP138A-D)
chr4	775937	777399	-	DDB_G0283483	srfD	NA
chr4	783267	784202	+	DDB_G0283591	DDB_G0283591	NA
chr4	785263	790130	+	DDB_G0283585	DDB_G0283585	NA
chr4	791068	791911	+	DDB_G0283541	yipf5	very similar to Yip1 domain family member 5 (YIPF5)%3B in yeast%2C YIP1 localizes to the Golgi and interacts with GTPases%3B contains four putative transmembrane domains
chr4	792074	794312	-	DDB_G0283543	prp40	ortholog of prp40%2C which in yeast is a U1 snRNP protein involved in splicing
chr4	794803	797775	+	DDB_G0283545	DDB_G0283545	NA
chr4	800136	800795	+	DDB_G0283547	rsmA	NA
chr4	800982	802155	-	DDB_G0283593	DDB_G0283593	NA
chr4	803052	803468	+	DDB_G0283549	DDB_G0283549	contains one C2 domain%2C which is is a Ca2%2B-dependent membrane-targeting module found in many cellular proteins involved in signal transduction or membrane trafficking
chr4	805455	809494	-	DDB_G0283595	DDB_G0283595	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr4	810010	815141	-	DDB_G0283551	DDB_G0283551	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity%3B highly similar to neighboring gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283553%22%3E%3Ci%3EDDB_G0283553%3C%2Fi%3E%3C%2Fa%3E
chr4	815506	820235	-	DDB_G0283553	DDB_G0283553	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity%3B highly similar to neighboring gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283551%22%3E%3Ci%3EDDB_G0283551%3C%2Fi%3E%3C%2Fa%3E
chr4	820858	822240	-	DDB_G0283539	crtA	Ca2%2B-binding protein with chaperone activity in the endoplasmic reticulum%3B plays a role in phagocytosis
chr4	822737	824361	-	DDB_G0283587	csn1	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8)
chr4	824798	826280	-	DDB_G0283555	DDB_G0283555	contains Dictyostelium spore coat protein N-terminal domain and 7 follistatin-like domains%3B similar to spore coat proteins CotA%2C CotB%2C and CotD%3B expressed in prespore cells
chr4	827565	829532	+	DDB_G0283557	DDB_G0283557	NA
chr4	829856	830504	+	DDB_G0283533	cbpB	enriched in prespore cells
chr4	830931	831128	-	DDB_G0283559	DDB_G0283559	NA
chr4	831598	831810	+	DDB_G0283561	DDB_G0283561	NA
chr4	833347	836465	-	DDB_G0283565	DDB_G0283565	NA
chr4	836774	837473	+	DDB_G0283567	DDB_G0283567	conserved protein with similarity to hepatitis B virus X interacting protein 
chr4	837650	846384	-	DDB_G0283535	DDB_G0283535	similar to H. sapiens DMXL1 and DMXL2 and D. melanogaster DmX%3B REMI mutant fails to aggregate%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0283535%22%3Ecommunity annotation%3C%2Fa%3E
chr4	847464	849687	+	DDB_G0283597	eif3B	EIF3B ortholog%2C the eukaryotic initiation factor eta subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr4	849934	850518	-	DDB_G0283537	rasS	regulates cell motility and endocytosis
chr4	851425	851742	-	DDB_G0283571	DDB_G0283571	NA
chr4	854108	854499	+	DDB_G0283573	DDB_G0283573	NA
chr4	855359	856264	+	DDB_G0283575	DDB_G0283575	catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione%3B enriched in prespore cells
chr4	856410	859921	-	DDB_G0283577	DDB_G0283577	NA
chr4	861957	863369	+	DDB_G0283579	crlD	similar to serpentine%2FG-protein coupled receptors%3B contains 7 putative transmembrane domains
chr4	863530	865415	-	DDB_G0283581	utp15	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr4	868454	873263	+	DDB_G0283605	yakA	belongs to the CMGC group of protein kinases%3B putative protein serine%2Fthreonine kinase
chr4	873651	877453	+	DDB_G0283623	DDB_G0283623	NA
chr4	877706	881475	-	DDB_G0283745	DDB_G0283745	similar to transportin 3%2C which in human seems to function in nuclear protein import as nuclear transport receptor
chr4	882607	883473	+	DDB_G0283625	DDB_G0283625	contains a Mob1 motif%2C however%2C it does not cluster with Mob1 proteins
chr4	883884	885363	-	DDB_G0283627	prsC	highly similar to PRS%2C involved in nucleotide%2C histidine%2C and tryptophan biosynthesis
chr4	885727	887358	-	DDB_G0283629	DDB_G0283629	belongs to a family of zinc transporters that are integral membrane proteins%2C which are found to increase tolerance to divalent metal ions%3B contains 6 putative transmembrane domains
chr4	888563	889499	+	DDB_G0283631	arfrp1	NA
chr4	889575	891258	-	DDB_G0283633	DDB_G0283633	NA
chr4	891645	892935	+	DDB_G0283635	wdr89	NA
chr4	893273	894967	+	DDB_G0283637	xrcc3	putative ortholog of XRCC3%2C which is involved in double-strand break repair%3B interacts with RAD51
chr4	895310	895535	+	DDB_G0283639	DDB_G0283639	NA
chr4	896653	896884	+	DDB_G0283643	DDB_G0283643	NA
chr4	897818	898626	-	DDB_G0283645	DDB_G0283645	very similar to %3Ci%3EDictyostelium%3C%2Fi%3E %3Ci%3EcbpF%3C%2Fi%3E%2C %3Ci%3EcbpG%3C%2Fi%3E%2C and %3Ci%3EcbpC%3C%2Fi%3E%3B contains two EF-hands
chr4	899345	900163	-	DDB_G0283611	cbpF	NA
chr4	901731	902526	-	DDB_G0283609	cbpG	NA
chr4	904975	905779	-	DDB_G0283613	cbpC	actin and calcium binding-protein located in the cell cortex
chr4	907070	907457	-	DDB_G0283647	DDB_G0283647	NA
chr4	908845	910395	+	DDB_G0283621	cutA	regulated by the MADS-box transcription factor SrfA during development
chr4	910617	911334	-	DDB_G0283649	DDB_G0283649	similar to the %3Ci%3ES. cerevisiae%3C%2Fi%3E LOT6%2C a FMN-dependent NAD(P)H:quinone reductase that may be involved in quinone detoxification
chr4	912876	914543	+	DDB_G0283607	eb1	member of EB1 family of proteins found at the tips of growing astral microtubules
chr4	915081	918076	+	DDB_G0283747	DDB_G0283747	NA
chr4	918296	920852	-	DDB_G0283651	DDB_G0283651	tyrosinases are copper monooxygenases that catalyzes the hydroxylation of monophenols and the oxidation of o-diphenols to o-quinols%3B binds two copper ions by 3 conserved His residues%3B there is an almost identical %3Ca href%3D%22%2Fgene%2FDDB_G0283653%22%3E downstream gene %3C%2Fa%3E
chr4	921967	924542	-	DDB_G0283653	DDB_G0283653	tyrosinases are copper monooxygenases that catalyzes the hydroxylation of monophenols and the oxidation of o-diphenols to o-quinols%3B binds two copper ions by 3 conserved His residues%3B there is an almost identical %3Ca href%3D%22%2Fgene%2FDDB_G0283653%22%3E upstream gene %3C%2Fa%3E
chr4	925419	926942	-	DDB_G0283655	DDB_G0283655	NA
chr4	927333	928611	-	DDB_G0283619	crlC	belongs to the serpentine%2FG-protein coupled receptor family
chr4	929556	934081	+	DDB_G0283749	DDB_G0283749	NA
chr4	934848	937361	+	DDB_G0283743	DDB_G0283743	NA
chr4	937904	938256	+	DDB_G0283657	ddx3_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0283661%22%3E%3Ci%3Eddx3%3C%2Fi%3E%3C%2Fa%3E
chr4	938852	939074	-	DDB_G0283659	DDB_G0283659_ps	putative pseudogene%3B fragment%3B similar to D. discoideum patatin gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0283553%22%3EDDB_G0283553%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283551%22%3EDDB_G0283551%3C%2Fa%3E
chr4	939305	941576	-	DDB_G0283661	ddx3	conserved RNA helicase%3B very similar to mammalian DDX3X and DDX3Y%2C and yeast DBP1
chr4	943186	944382	+	DDB_G0283663	ppiD	ortholog of the mammalian PPID%3B peptidyl-prolyl cis-trans isomerase (PPIase) accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr4	944514	944756	+	DDB_G0295481	DDB_G0295481_ps	putative pseudogene%3B fragment very similar to %3Ci%3EDictyostelium%3C%2Fi%3E ppiD
chr4	945236	945694	+	DDB_G0283665	DDB_G0283665_ps	putative pseudogene%3B similar to %3Ci%3EDictyostelium%3C%2Fi%3E calcium binding proteins
chr4	946222	948830	+	DDB_G0283667	DDB_G0283667	conserved protein
chr4	949430	952310	-	DDB_G0283601	pppA	scaffold subunit of the serine%2Fthreonine protein phosphatase 2A%2C  composed of a catalytic subunit (pho2A)%2C a regulatory subunit (phr2AB) and a scaffold subunit (pppA)%3B an additional regulatory B56 (psrA) subunit has been identified
chr4	953002	953325	+	DDB_G0283669	DDB_G0283669	conserved ubiquinol-cytochrome c oxidoreductase subunit%2C a component of the mitochondrial inner membrane electron transport chain
chr4	953712	954208	-	DDB_G0283671	grn	very similar to H. sapiens granulins1-7%2C which are products of the precurser gene GRN%3B defects in GRN cause the ubiquitin-positive frontotemporal dementia (UP-FTD) 
chr4	954966	956651	+	DDB_G0283673	gpi	catalyzes the reaction D-glucose 6-phosphate %3C%3D%3E D-fructose 6-phosphate
chr4	956823	956877	-	DDB_G0294415	r21	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	958244	958301	-	DDB_G0295565	r49	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	959090	959146	-	DDB_G0295567	r50	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	959587	959644	-	DDB_G0295569	r51	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	960281	960338	-	DDB_G0295571	r22	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	961592	961649	+	DDB_G0295573	r52	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	961972	963150	-	DDB_G0283675	DDB_G0283675	NA
chr4	963963	964844	+	DDB_G0283677	DDB_G0283677	NA
chr4	965063	966191	-	DDB_G0283603	rab32A	similar to rab32 and rab38
chr4	967091	968259	-	DDB_G0283679	psmB7	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr4	968949	972603	-	DDB_G0283599	limA	NA
chr4	973798	978136	-	DDB_G0283681	DDB_G0283681	similar to STAG (stromal antigen) proteins%2C which are subunits of a protein complex required for sister chromatid cohesion in eukaryotes
chr4	978468	980033	-	DDB_G0283683	DDB_G0283683	has similarity to proteins of the Ribonuclease Inhibitor (RNI) family
chr4	980287	981874	+	DDB_G0283685	utp23	putative U3 snoRNP protein%3B ortholog of H. sapiens C8orf53 and S. cerevisiae UTP23
chr4	982205	984735	+	DDB_G0283687	DDB_G0283687	similar to CC1-like splicing factors%2C characterized by an N-terminal arginine-rich low complexity domain followed by three RNA recognition domains%3B similar to human RBM23 and RBM39
chr4	985671	986213	-	DDB_G0283689	DDB_G0283689	NA
chr4	986987	988734	+	DDB_G0283691	DDB_G0283691	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D%3B contains a predicted signal peptide
chr4	989598	989852	+	DDB_G0347783	DDB_G0347783	NA
chr4	990291	990579	+	DDB_G0283693	DDB_G0283693	NA
chr4	990708	992008	-	DDB_G0283695	DDB_G0283695	NA
chr4	992255	995015	+	DDB_G0283697	DDB_G0283697	NA
chr4	995559	999815	-	DDB_G0283699	phg2	serine%2Fthreonine kinase regulating cell substrate adhesion%2C phagocytosis%2C motility%2C and actin organization%3B member of the TKL (tyrosine kinase-like) group%3B belongs to the ARK (ankyrin repeat-containing kinase) family%2C although it does not contain ankyrin repeats
chr4	1000722	1002269	-	DDB_G0283701	guaB	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B NAD %2B IMP %3C%3D%3E xanthosine-5-phosphate %2B NADH%2C the first step of GMP biosynthesis
chr4	1003190	1003627	-	DDB_G0283703	DDB_G0283703	NA
chr4	1004930	1005106	+	DDB_G0283705	DDB_G0283705	NA
chr4	1005690	1007306	-	DDB_G0283707	DDB_G0283707	conserved protein in ciliates and plants%3B contains 9 predicted transmembrane domains%2C including one signal peptide%3B there is an almost identical D. discoideum protein%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293610%22%3E%3Ci%3EDDB_G0293610 %3C%2Fi%3E%3C%2Fa%3E
chr4	1009391	1010770	+	DDB_G0283709	osbH	ortholog of H. sapiens OSBPL6 and S. cerevisiae OSH2 involved in sterol metabolism
chr4	1011158	1011491	-	DDB_G0283711	DDB_G0283711	highly similar to other hssA%2F2C%2F7E family proteins
chr4	1012257	1012584	+	DDB_G0283713	DDB_G0283713	highly similar to other Dictyostelium small coiled-coil proteins
chr4	1012994	1016773	-	DDB_G0283715	DDB_G0283715	NA
chr4	1018005	1019789	-	DDB_G0283717	pigX	NA
chr4	1020192	1022856	-	DDB_G0283615	rpkA	seven transmembrane G-protein coupled receptor (GPCR) that bears a C-terminal phosphatidylinositol-4-phosphate 5-kinase (PIP5K) domain
chr4	1023936	1028052	-	DDB_G0283719	DDB_G0283719	NA
chr4	1029584	1031872	+	DDB_G0283721	DDB_G0283721	almost identical to the upstream gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283723%22%3E%3Ci%3EDDB_G0283723%3C%2Fi%3E%3C%2Fa%3E
chr4	1033128	1035392	+	DDB_G0283723	DDB_G0283723	almost identical to the downstream gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283721%22%3E%3Ci%3EDDB_G0283721%3C%2Fi%3E%3C%2Fa%3E
chr4	1035645	1037944	+	DDB_G0283725	DDB_G0283725_ps	putative pseudogene%2C very similar to pyridoxal phosphate-dependent decarboxylase family genes
chr4	1038776	1039531	+	DDB_G0283727	DDB_G0283727	NA
chr4	1039785	1041314	-	DDB_G0283729	DDB_G0283729	NA
chr4	1041764	1042491	-	DDB_G0283731	DDB_G0283731	similar to D. purpureum protein%3B contains a histidine rich region
chr4	1042995	1044131	+	DDB_G0283733	DDB_G0283733	NA
chr4	1044239	1045646	-	DDB_G0283751	mcfM	ortholog of SLC25A32%2C involved in transport of folate across the mitochondrial membrane  %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr4	1046052	1046527	+	DDB_G0283735	dnajc19	putative component of the PAM complex%2C required for the ATP-dependent translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix%3B defects in DNAJC19 in human cause dilated cardiomyopathy with ataxia (DCMA)%3B contains one putative N-terminal signal sequence
chr4	1046828	1047289	-	DDB_G0283737	urm1	homolog of human and S. cerevisiae URM1%3B yeast URM1 is involved in tRNA modification and is alsoindirectly involved in oxidative stress response and regulation of budding and haploid invasive growth
chr4	1048980	1049683	+	DDB_G0283741	rpl26	protein component of the large (60S) ribosomal subunit
chr4	1050017	1052135	-	DDB_G0283753	DDB_G0283753	NA
chr4	1053164	1056325	-	DDB_G0283617	cdc25	similar to mammalian dual specificity protein phosphatases cdc25B and cdc25C%2C involved in the G2%2FM transition through dephosphorylation of cdc2 at Tyr15 and Thr14
chr4	1060450	1062283	+	DDB_G0283855	gpr89	localizes to the ER and Golgi%2C regulates developmental gene expression and is involved predominantly in late development
chr4	1062604	1066349	+	DDB_G0283857	lig3	ATP-dependent DNA ligase%3B contains the BRCT domain%2C which is also found in BRCA1%3B interacts with XRCC1
chr4	1066871	1072160	+	DDB_G0283859	DDB_G0283859	similar to human peregrin (BR140) protein
chr4	1072483	1073637	+	DDB_G0283861	DDB_G0283861	NA
chr4	1074074	1076128	-	DDB_G0283863	DDB_G0283863	NA
chr4	1077530	1078425	-	DDB_G0283865	timm22	mediates the membrane insertion of multi-spanning inner-membrane proteins that have internal targeting signals
chr4	1079549	1081769	+	DDB_G0283771	DDB_G0283771	%3Cb%3ECommunity annotation: %3C%2Fb%3EDDB_G0283771 shows weak similarities to several kinesin family proteins. The gene is overexpressed sixfold in a Dictyostelium %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA mutant%3C%2Fa%3E lacking the Dicty retinoblastoma homolog rblA (Doquang et al%2C in preparation). 8 of the known Dicty kifs are overexpressed at least threefold in this strain%2C which presumably relates to a general overexpression of genes involved in DNA synthesis and mitosis. This supports the assignment of DDB_G0283771 as a kif%2C and suggests a role in cell cycle progression. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E
chr4	1081883	1083350	-	DDB_G0283773	DDB_G0283773	putative GTPase%2C very conserved in protozoa and fungi
chr4	1083586	1087242	+	DDB_G0283775	DDB_G0283775	NA
chr4	1087508	1087756	-	DDB_G0283777	DDB_G0283777	NA
chr4	1089062	1090168	+	DDB_G0283781	DDB_G0283781	NA
chr4	1091245	1091694	+	DDB_G0283783	DDB_G0283783	NA
chr4	1092858	1094270	+	DDB_G0283867	cprC	NA
chr4	1094707	1098702	+	DDB_G0283869	DDB_G0283869	contains 3 EGF-like domains%2C a predicted signal sequence and one N-terminal transmembrane domain%3B very similar to it%27s two downstream neighbors%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283785%22%3E DDB_G0283785%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283787%22%3E DDB_G0283787 %3C%2Fa%3E%2C and also a conserved family in D. purpureum
chr4	1099059	1102810	+	DDB_G0283785	DDB_G0283785	contains 2 EGF-like domains%2C a predicted signal sequence and one N-terminal transmembrane domain%3B very similar to it%27s upstream and downstream neighbors%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283787%22%3E DDB_G0283787%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283869%22%3E DDB_G0283869 %3C%2Fa%3E%2C and also a conserved family in D. purpureum
chr4	1103072	1106881	+	DDB_G0283787	DDB_G0283787	contains 2 EGF-like domains%2C a predicted signal sequence and one N-terminal transmembrane domain%3B very similar to it%27s two upstream neighbors%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283785%22%3E DDB_G0283785%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283869%22%3E DDB_G0283869 %3C%2Fa%3E%2C and also a conserved family in D. purpureum
chr4	1107655	1109115	+	DDB_G0283789	dimt1l	essential protein that dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3%27-end of 18S rRNA in the 40S particle in %3Ci%3ES. cerevisiae%3C%2Fi%3E
chr4	1109469	1110788	-	DDB_G0283791	DDB_G0283791	NA
chr4	1114386	1116616	-	DDB_G0283793	DDB_G0283793	NA
chr4	1117216	1118052	-	DDB_G0283795	commd3	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr4	1118346	1119815	-	DDB_G0283797	DDB_G0283797	contains a putative signal peptide
chr4	1120333	1121659	-	DDB_G0283799	DDB_G0283799	NA
chr4	1121919	1122538	+	DDB_G0283801	fam96B	NA
chr4	1122911	1123829	+	DDB_G0283803	DDB_G0283803	NA
chr4	1124176	1125432	-	DDB_G0283805	adkA	catalyzes the reaction AMP %2B ATP %3C%3D%3E ADP %2B ADP in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis
chr4	1126533	1127306	+	DDB_G0283871	DDB_G0283871	expressed in pstO cells
chr4	1128255	1128698	+	DDB_G0283807	DDB_G0283807	NA
chr4	1129091	1129664	-	DDB_G0283873	tgrI_ps1	putative pseudogene%3B immunoglobulin E-set family gene
chr4	1130346	1131152	-	DDB_G0283809	dcp2_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0283315%22%3E%3Ci%3Edcp2%3C%2Fi%3E%3C%2Fa%3E 
chr4	1132285	1133349	+	DDB_G0283767	dct	actin filament bundling protein
chr4	1134008	1135291	+	DDB_G0283877	dus2l	ortholog of S. cerevisiae SMM1 and the animal DUS2L%3B catalyzes the synthesis of dihydrouridine%2C a modified base found in the D-loop of tRNAs
chr4	1135639	1137330	-	DDB_G0283755	arpC	component of the Dictyostelium Arp2%2FArp3 complex
chr4	1138835	1141696	+	DDB_G0283769	hbs1	NA
chr4	1142351	1142941	-	DDB_G0283879	DDB_G0283879	NA
chr4	1144131	1145221	+	DDB_G0283811	mcfR	similar to Grave disease carrier protein (slc25a16)%2C belongs to the substrate carrier proteins that are involved in transport of molecules across the mitochondrial membrane%3B may transport coenzyme A %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr4	1145359	1146736	-	DDB_G0283813	hmgL	catalyzes the reaction 3-hydroxy-3-methyl-glutaryl-CoA %3D acetoacetate %2B acetyl-CoA
chr4	1148242	1149573	-	DDB_G0283815	DDB_G0283815	NA
chr4	1149949	1150830	+	DDB_G0283817	DDB_G0283817	NA
chr4	1151090	1152640	-	DDB_G0283765	hgd	reduction of homogentisic acid reductase results in  accumulation of an intermediate in the tyrosine degradative pathway%2C homogentisic acid%2C which is spontaneously oxidized%2C resulting in a brown phenotype%3B catalyzes the reaction homogentisate %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E 4-maleylacetoacetate
chr4	1153703	1155501	+	DDB_G0283819	DDB_G0283819	NA
chr4	1155677	1158750	-	DDB_G0283821	DDB_G0283821	kinase domain similar to %3Ci%3ES. pombe%3C%2Fi%3E cdc7%2C cell division control protein 7 which plays a role in cytokinesis
chr4	1160700	1165945	+	DDB_G0283883	mlh3	MLH3 ortholog%3B required for DNA mismatch repair
chr4	1166070	1167758	-	DDB_G0283885	DDB_G0283885	member of a gene family comprising %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283887%22%3E%3Ci%3EDDB_G0283887%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283885%22%3E%3Ci%3EDDB_G0283885%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275891%22%3E%3Ci%3EDDB_G0275891_ps%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275279%22%3E%3Ci%3EDDB_G0275279%3C%2Fi%3E%3C%2Fa%3E%2C similar to hypothetical protein MT3488 from Mycobacterium tuberculosis
chr4	1170844	1172651	-	DDB_G0283887	DDB_G0283887	member of a gene family comprising %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283887%22%3E%3Ci%3EDDB_G0283887%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283885%22%3E%3Ci%3EDDB_G0283885%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275891%22%3E%3Ci%3EDDB_G0275891_ps%3C%2Fi%3E%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0275279%22%3E%3Ci%3EDDB_G0275279%3C%2Fi%3E%3C%2Fa%3E%2C similar to hypothetical protein MT3488 from Mycobacterium tuberculosis
chr4	1174977	1176878	-	DDB_G0283889	DDB_G0283889	NA
chr4	1177277	1177982	+	DDB_G0283823	DDB_G0283823	NA
chr4	1178221	1179642	-	DDB_G0283825	DDB_G0283825	NA
chr4	1180565	1183282	+	DDB_G0283827	DDB_G0283827	NA
chr4	1183400	1184878	-	DDB_G0283829	DDB_G0283829	similar to human ODR4 (odorant response abnormal protein 4)%3B contains one putative transmembrane domain
chr4	1185329	1186424	-	DDB_G0283831	DDB_G0283831	NA
chr4	1187328	1190669	-	DDB_G0283833	DDB_G0283833	NA
chr4	1191439	1192760	+	DDB_G0283835	rae1	ortholog of RNA export protein rae1
chr4	1193106	1194623	-	DDB_G0283891	ube1c	conserved catalytic subunit of the dimeric UBE1C-APPBP1 E1 enzyme%2C which activates NEDD8%3B necessary for cell cycle progression through the S-M checkpoint
chr4	1195917	1198139	+	DDB_G0283837	DDB_G0283837	proteins containing the actin depolymerisation factor (ADF)%2Fcofilin-like domain sever actin filaments and bind to actin monomers
chr4	1198222	1201082	-	DDB_G0283839	grlN	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr4	1202486	1204316	+	DDB_G0283841	alg6	CAZy family GT57%3B catalyzes N-linked glucosylation
chr4	1204398	1222939	-	DDB_G0283893	DDB_G0283893	similar to H. sapiens 600 kDa retinoblastoma-associated factor and A. thaliana auxin transport protein (BIG)
chr4	1223477	1224134	-	DDB_G0283843	DDB_G0283843	NA
chr4	1227055	1227727	+	DDB_G0283845	DDB_G0283845	carboxyl terminal portion of the gene belongs to the SAP30 family
chr4	1228686	1230545	+	DDB_G0283847	DDB_G0283847	catalyzes the reaction: S-adenosyl-L-methionine %2B phospholipid olefinic fatty acid %3D S-adenosyl-L-homocysteine %2B phospholipid cyclopropane fatty acid%3B underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr4	1232305	1235646	+	DDB_G0283759	DDB_G0283759	NA
chr4	1235916	1238225	+	DDB_G0283761	pgtA	catalyzes the beta1%2C3 addition of galactose to GlcNAc-Skp1 and the alpha1%2C2 addition of fucose to GalBeta1%2C3GlcNAc-Skp1 (FpaA%2FFpaB)
chr4	1238328	1239107	-	DDB_G0283763	grpE	similar to S. cerevisiae MGE1%2C and H. sapiens GrpE%2C involved in protein import into mitochondria
chr4	1239874	1240653	-	DDB_G0283849	DDB_G0283849	NA
chr4	1241175	1242406	-	DDB_G0283757	rab1A	similar to rab1B
chr4	1243225	1246032	+	DDB_G0283897	DDB_G0283897	NA
chr4	1248575	1251382	+	DDB_G0283899	mgp4	NA
chr4	1253142	1254007	-	DDB_G0283851	DDB_G0283851	NA
chr4	1254332	1256100	-	DDB_G0283901	DDB_G0283901	NA
chr4	1259472	1262994	+	DDB_G0283983	hfnA	contains an N-terminal filamin%2FABP280 repeat%2C and a C-terminal HECT (Homologous to the E6-AP Carboxyl Terminus) domain%2C the latter common in ubiquitin ligases
chr4	1263489	1265251	+	DDB_G0283985	DDB_G0283985	NA
chr4	1265347	1267125	-	DDB_G0283911	DDB_G0283911	highly similar to neighboring gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283913%22%3E%3Ci%3EDDB_G0283913%3C%2Fi%3E%3C%2Fa%3E
chr4	1267681	1269684	-	DDB_G0283913	DDB_G0283913	large molecular weight protein that contains a hsp20 domain%3B highly similar to neighboring gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283911%22%3E%3Ci%3EDDB_G0283911%3C%2Fi%3E%3C%2Fa%3E 
chr4	1270973	1271674	+	DDB_G0283915	DDB_G0283915	NA
chr4	1272110	1273864	+	DDB_G0283917	sir2A	NAD-dependent deacetylase Sirutin 2 family protein%2C that regulates various biological processes by deacetylating histones and other target proteins%3B expressed more highly during vegetative growth 
chr4	1275553	1278795	+	DDB_G0283919	DDB_G0283919	the protein phosphatase 2C-related domain occurs in protein phosphatase 2C (PPC2) as well as in other proteins%2C such as pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase
chr4	1280148	1283703	+	DDB_G0283987	purC%2FE	bifunctional enzyme composed of SAICAR synthase and AIR carboxylase%2C that catalyze steps in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis
chr4	1284281	1287103	+	DDB_G0283989	DDB_G0283989	one of three paralogs in %3Ci%3EDictyostelium%3C%2Fi%3E (other genes: %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293204%22%3E%3Ci%3EDDB_G0293204%3C%2Fi%3E%3C%2Fa%3E) that are putative hydrolases
chr4	1287653	1288744	+	DDB_G0283991	DDB_G0283991	NA
chr4	1289307	1292881	+	DDB_G0283993	DDB_G0283993	contains an immunoglobulin E-set domain
chr4	1293218	1296843	+	DDB_G0283995	DDB_G0283995	NA
chr4	1297288	1298315	+	DDB_G0283921	ctsB	member of the papain cysteine protease family%2C which has a wide range of specificities
chr4	1298443	1301612	+	DDB_G0283997	DDB_G0283997_ps	putative pseudogene%3B similar to a family of D. discoideum protein family of unknown function%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0277653%22%3EDDB_G0277653%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0305538%22%3EDDB_G0305538%3C%2Fa%3E
chr4	1301821	1306170	-	DDB_G0283923	DDB_G0283923	NA
chr4	1306681	1307437	-	DDB_G0283925	DDB_G0283925	NA
chr4	1307685	1309325	-	DDB_G0283927	DDB_G0283927	putative protein serine%2Fthreonine kinase%3B similar to vertebrate Nek kinases which are involved in regulation of mitosis
chr4	1309513	1311425	-	DDB_G0283999	DDB_G0283999	NA
chr4	1312340	1320136	-	DDB_G0284001	pks22	putative type I iterative polyketide synthase
chr4	1320998	1322607	+	DDB_G0283929	cyp517A1	enriched in prestalk cells
chr4	1322762	1330597	-	DDB_G0283931	pks23	putative type I iterative polyketide synthase
chr4	1331360	1332963	+	DDB_G0283933	cyp517A4	NA
chr4	1333704	1334645	+	DDB_G0283935	DDB_G0283935	similar to bacterial short-chain dehydrogenase%2Freductase family proteins
chr4	1335851	1337901	+	DDB_G0283937	sec1	highly similar to mammalian Sec1 (also known as syntaxin binding protein 1)%2C which plays a role in vesicle transport by binding to t-SNAREs%3B expressed in prespore cells%2C involved in osmoregulation and hence cell motility
chr4	1338263	1341418	+	DDB_G0283939	DDB_G0283939	NA
chr4	1341707	1342150	-	DDB_G0283941	DDB_G0283941	NA
chr4	1342529	1344406	-	DDB_G0283943	DDB_G0283943	catalyzes the reaction aldehyde %2B NAD%3Csup%3E%2B%3C%2Fsup%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%3Csup%3E%2B%3C%2Fsup%3E
chr4	1345149	1348226	+	DDB_G0283945	DDB_G0283945	NA
chr4	1349351	1350451	+	DDB_G0283947	DDB_G0283947	NA
chr4	1350512	1351909	-	DDB_G0283949	DDB_G0283949	NA
chr4	1352908	1354941	+	DDB_G0283951	DDB_G0283951	contains a predicted signal peptide%3B catalyzes the reaction sn-glycerol 3-phosphate %2B a quinone %3D glycerone phosphate %2B a quinol
chr4	1355165	1362603	-	DDB_G0283953	mybU	contains one Myb DNA-binding domain
chr4	1364111	1368153	-	DDB_G0283955	gacG	NA
chr4	1370478	1373603	-	DDB_G0283957	msh4	MSH4 ortholog
chr4	1374141	1375052	+	DDB_G0283959	DDB_G0283959	NA
chr4	1375647	1376558	+	DDB_G0283961	DDB_G0283961	NA
chr4	1376667	1379177	-	DDB_G0283909	spc98	centrosomal protein involved in microtubule nucleation
chr4	1379527	1382094	+	DDB_G0284003	ndc80	ortholog of NDC80 (also known as HEC1 and TID3)%2C a subunit of the kinetochore complex involved in microtubule binding and the spindle assembly checkpoint %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation: %3C%2Fb%3Endc80 is overexpressed 16-fold in a Dictyostelium %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA mutant%3C%2Fa%3E strain lacking the retinoblastoma-like gene(Doquang et al%2C in preparation). The majority of genes involved in mitosis and DNA replication are overexpressed in this strain%3B this suggests a role for ndc80 in Dictyostelium cell cycle progression. %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E
chr4	1382400	1382738	-	DDB_G0283963	fam32	conserved protein
chr4	1382938	1384703	+	DDB_G0283965	pigA	CAZy family GT4%3B subunit of the transferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-N-acetylglucosamine to phosphatidylinositol (PI)
chr4	1385123	1386548	-	DDB_G0283903	erkB	NA
chr4	1387840	1393254	+	DDB_G0283967	DDB_G0283967	NA
chr4	1394958	1397005	+	DDB_G0283907	pkaC	AGC group%2C PKA family protein kinase%3B protein serine%2Fthreonine kinase%3B regulates spore cell differentiation
chr4	1397618	1397902	-	DDB_G0284005	DDB_G0284005	NA
chr4	1398686	1399744	-	DDB_G0284007	DDB_G0284007	NA
chr4	1400103	1401870	+	DDB_G0283969	trmt11	required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs
chr4	1401996	1405050	-	DDB_G0283971	DDB_G0283971	contains an N-terminal ubiquitin domain%3B very similar to D. purpureum protein
chr4	1405614	1407920	+	DDB_G0283973	DDB_G0283973	NA
chr4	1408395	1409228	+	DDB_G0283975	DDB_G0283975	NA
chr4	1409294	1411915	-	DDB_G0283977	DDB_G0283977	NA
chr4	1413537	1417136	+	DDB_G0283979	DDB_G0283979	NA
chr4	1418066	1421134	-	DDB_G0283981	pms1	ortholog of H. sapiens PMS2 and S. cerevisiae PMS1%3B required for DNA mismatch repair
chr4	1421546	1422592	-	DDB_G0294559	DDB_G0294559	NA
chr4	1423354	1425584	-	DDB_G0283905	phr2aB	regulatory subunit of protein phosphatase 2A%2C  composed of a catalytic subunit (pho2A)%2C a regulatory subunit (phr2AB) and a scaffold subunit (pppA)%3B an additional regulatory B56 (psrA) subunit has been identified
chr4	1428069	1429134	+	DDB_G0284009	ubcC	NA
chr4	1429547	1430576	-	DDB_G0284011	DDB_G0284011	NA
chr4	1432537	1433609	+	DDB_G0284013	spc25	ortholog of Spc25 which interacts with Ndc80 in the attachment of microtubules to kinetochores %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation: %3C%2Fb%3E spc25 is overexpressed 16-fold in a %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA mutant%3C%2Fa%3E strain lacking the Dicty retinoblastoma like gene. This strain overexpresses most genes known to be involved in DNA replication and mitosis%2C but few other genes (Doquang et al%2C in preparation). This suggests that spc25 is involved in Dictyostelium cell cycle progression.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E 
chr4	1433731	1436234	-	DDB_G0284015	DDB_G0284015	NA
chr4	1436851	1439670	+	DDB_G0284017	ddx10	ortholog of H. sapiens DDX10 and S. cerevisiae HCA4 (Helicase CA)
chr4	1440123	1442348	-	DDB_G0284025	DDB_G0284025	NA
chr4	1444241	1446775	-	DDB_G0284019	DDB_G0284019	NA
chr4	1447496	1448281	-	DDB_G0284021	DDB_G0284021	NA
chr4	1449089	1450807	-	DDB_G0284023	bzpL	NA
chr4	1458434	1459279	+	DDB_G0284031	DDB_G0284031	NA
chr4	1459718	1462937	-	DDB_G0284029	pkgD	AGC group protein serine%2Fthreonine kinase%3B similar to cAMP-activated protein kinase catalytic subunits
chr4	1467489	1471225	+	DDB_G0284049	DDB_G0284049	the amino terminal portion is similar to a D. purpureum protein
chr4	1471982	1473605	+	DDB_G0284051	DDB_G0284051	NA
chr4	1473938	1474783	+	DDB_G0284053	DDB_G0284053	NA
chr4	1474815	1476375	-	DDB_G0284055	DDB_G0284055	NA
chr4	1478033	1478404	+	DDB_G0284057	DDB_G0284057	NA
chr4	1478818	1482847	+	DDB_G0284059	DDB_G0284059	has similarity to the H. sapiens SET and MYND domain-containing protein 4 (SMYD4)
chr4	1483793	1484774	+	DDB_G0284061	DDB_G0284061	NA
chr4	1485717	1486784	+	DDB_G0284063	DDB_G0284063	NA
chr4	1486936	1490134	-	DDB_G0284141	atp7a	P-type ATPase known to play a role in Menkes syndrome
chr4	1490360	1492566	+	DDB_G0284143	DDB_G0284143	NA
chr4	1493285	1494732	-	DDB_G0284065	rapgap9	similar to H. sapiens Rap1GAP%3B involved in morphogenesis%2C development%2C and cell adhesion
chr4	1497378	1498460	+	DDB_G0284067	clybl	conserved eukaryotic protein
chr4	1498595	1499943	-	DDB_G0284069	DDB_G0284069	NA
chr4	1500251	1502171	-	DDB_G0284041	rcdII	NA
chr4	1503516	1506219	+	DDB_G0284071	rnrA	catalyzes the reaction 2%27-deoxyribonucleoside diphosphate %2B thioredoxin disulfide %2B H%3Csub%3E2%3C%2Fsub%3EO %3D ribonucleoside diphosphate %2B reduced thioredoxin
chr4	1506777	1509678	+	DDB_G0284073	DDB_G0284073	similar to %3Ci%3EDictystelium%3C%2Fi%3E cell surface glycoproteins gp130%2C and GP138A%2C B%2C C%2C and D
chr4	1509861	1520159	-	DDB_G0284045	dhkG	NA
chr4	1521553	1523257	+	DDB_G0284043	aplA	similar to human proactivator polypeptide precursor saposin A region
chr4	1523365	1525118	-	DDB_G0284145	DDB_G0284145	NA
chr4	1525708	1529993	+	DDB_G0284075	elp1	similar to S. cerevisiae IKI3%2C subunit of the RNA polymerase II elongator complex%2C and mammalian IKAP proteins
chr4	1530962	1532422	+	DDB_G0284077	DDB_G0284077	NA
chr4	1532512	1533541	-	DDB_G0284147	DDB_G0284147	NA
chr4	1533705	1535576	-	DDB_G0284149	DDB_G0284149	ortholog of yeast VID24%2C a peripheral membrane protein located at Vid (vacuole import and degradation) vesicles
chr4	1535647	1536451	+	DDB_G0284035	efa1B	NA
chr4	1536747	1537854	+	DDB_G0284151	DDB_G0284151	NA
chr4	1538387	1539423	+	DDB_G0284079	DDB_G0284079	contains two ankyrin repeats and an RA domain%2C which plays a role in RasGTP activation in mammals and mating in yeast%3B highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0280181%22%3E%3Ci%3EDDB_G0280181%3C%2Fi%3E%3C%2Fa%3E
chr4	1542455	1544698	-	DDB_G0284047	abcF2	consists of two ABC domains and lacks a transmembrane domain
chr4	1545923	1547930	-	DDB_G0284153	DDB_G0284153	NA
chr4	1548205	1549203	+	DDB_G0284083	DDB_G0284083	NA
chr4	1549462	1550559	+	DDB_G0284085	DDB_G0284085	NA
chr4	1550807	1554172	+	DDB_G0284087	DDB_G0284087	NA
chr4	1554448	1556063	-	DDB_G0284089	cyp519B1	NA
chr4	1556685	1557407	-	DDB_G0284091	DDB_G0284091	NA
chr4	1558362	1559293	+	DDB_G0284093	rps16	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S16 homolog
chr4	1559578	1560556	-	DDB_G0284095	DDB_G0284095	NA
chr4	1561847	1565439	+	DDB_G0284155	DDB_G0284155	contains two PLDc domains%3B has similarity to mammalian phospholipase D2
chr4	1565830	1568043	-	DDB_G0284097	DDB_G0284097	NA
chr4	1569018	1570493	-	DDB_G0284099	DDB_G0284099	NA
chr4	1571395	1572487	+	DDB_G0284101	snrpA1	ortholog of human SNRPA1%2C a component of the U2 snRNP involved in mRNA splicing
chr4	1573183	1575363	-	DDB_G0284103	mybZ	contains one Myb DNA-binding domain
chr4	1580531	1582704	-	DDB_G0284105	DDB_G0284105	similar to Homo sapiens nuclear receptor-interacting factor NRIF4
chr4	1583322	1586939	+	DDB_G0284157	DDB_G0284157	NA
chr4	1589109	1589190	-	DDB_G0295231	tRNA-Ser-UGA-8	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr4	1589376	1592573	-	DDB_G0284107	pgtC	CAZy family GT2%2F4%3B contains two glycosyltransferase domains
chr4	1593040	1595399	+	DDB_G0284037	DDB_G0284037	weakly similar to 26S proteasome regulatory subunit RPN11 (MPR1 protein)%3B REMI mutant forms aberrant fruiting bodies (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0284037%22%3Ecommunity annotation%3C%2Fa%3E) 
chr4	1595576	1596770	-	DDB_G0284039	pprA	similar to protein phosphatase PP1 regulatory subunit SDS22 from Schizosaccharomyces pombe
chr4	1597279	1597774	+	DDB_G0284161	DDB_G0284161	NA
chr4	1598186	1598452	+	DDB_G0284163	DDB_G0284163	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon%2C but the second exon is shorter  
chr4	1599639	1600013	+	DDB_G0284109	DDB_G0284109	NA
chr4	1601233	1601607	+	DDB_G0284111	DDB_G0284111	NA
chr4	1602101	1602932	-	DDB_G0349532	tgrA_ps10	putative pseudogene%3B fragment of immunoglobulin E-set family genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0291622%22%3E%3Ci%3EtgrA1%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0291666%22%3E%3Ci%3EtgrA2%3C%2Fi%3E%3C%2Fa%3E
chr4	1603328	1605870	-	DDB_G0349530	DDB_G0349530	NA
chr4	1606151	1606472	-	DDB_G0284165	DDB_G0284165	NA
chr4	1607949	1608528	+	DDB_G0284115	DDB_G0284115	NA
chr4	1608856	1609984	+	DDB_G0284117	phbB	ortholog of the yeast Phb2p and other prohibitins that are inner mitochondrial membrane chaperones that stabilize newly synthesized proteins%3B also suggested to play a role in cell senescence
chr4	1610129	1611458	-	DDB_G0284167	DDB_G0284167	NA
chr4	1612603	1613308	-	DDB_G0284169	DDB_G0284169	contains 3 predicted transmembrane domains and an additional putative signal sequence%3B part of a larger gene family in D. discoideum%2C also present in other dictyostelids
chr4	1614014	1614774	-	DDB_G0284119	DDB_G0284119	contains 3 predicted transmembrane domains and an additional putative signal sequence%3B member of a larger gene family in D. discoideum%2C also present in other dictyostelids
chr4	1615547	1617128	-	DDB_G0284121	DDB_G0284121	contains two predicted transmembrane domains
chr4	1617796	1618926	-	DDB_G0284125	DDB_G0284125	NA
chr4	1619168	1620657	+	DDB_G0284127	DDB_G0284127	NA
chr4	1622284	1624946	+	DDB_G0284129	e2f	%3Cb%3ECommunity annotation: %3C%2Fb%3E Dicty%27s single E2F is likely to be an %22activator E2F%22  rather than an %22inhibitor E2F%22 (see  %3Ca target %3D%22new%22 href%3D%22http:%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F11823794%22%3E Trimarchi and Lees%2C 2001%3C%2Fa%3E)  as it has both a perfect-match 9-amino acid transactivation signal  (GVLDLKVAS) and a strong nuclear localization signal (TRKRRS).  %3Ci%3EHarry MacWilliams%2C November 2008 %3C%2Fi%3E%3Cbr%3E There appear to be %3Ca target %3D%22new%22 href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0282499%22%3Efurther%3C%2Fa%3E E2F family members in Dicty.  %3Ci%3EHarry MacWilliams%2C February 2011%3C%2Fi%3E 
chr4	1625572	1627560	+	DDB_G0284131	DDB_G0284131	NA
chr4	1629570	1632993	+	DDB_G0284133	DDB_G0284133	similar to P. pallidum protein%3B weak similarity to PB1 domain in amino terminal region
chr4	1634829	1637741	+	DDB_G0284135	DDB_G0284135	NA
chr4	1638105	1639565	-	DDB_G0284137	DDB_G0284137	NA
chr4	1640056	1641798	-	DDB_G0284139	DDB_G0284139	NA
chr4	1643184	1645262	-	DDB_G0284179	DDB_G0284179	NA
chr4	1645755	1651739	-	DDB_G0284171	chdA	CHD gene family protein containing a chromodomain%2C a helicase domain%2C and a DNA-binding domain%3B similar to H. sapiens chromodomain-helicase-DNA-binding protein 2 (CHD-2) (SwissProt: O14647)%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr4	1652572	1653456	-	DDB_G0284173	DDB_G0284173	NA
chr4	1653717	1656680	+	DDB_G0284175	DDB_G0284175	similar to S. pombe mus81 in the 3%27 region%3B also contains DNA polymerase B-like domain%2C SAM domain and SWIM-type zinc finger domains
chr4	1658818	1662279	+	DDB_G0284177	DDB_G0284177	NA
chr4	1662690	1662746	-	DDB_G0295575	r23C	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	1663884	1663941	+	DDB_G0295577	r24A	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	1664505	1666097	+	DDB_G0284305	DDB_G0284305_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	1666945	1667001	-	DDB_G0295579	r23B	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	1667874	1667905	+	DDB_G0295581	r53	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	1668202	1668259	+	DDB_G0295583	r26	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	1668807	1668863	-	DDB_G0295585	r23A	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	1669261	1670304	+	DDB_G0284189	DDB_G0284189	NA
chr4	1670895	1673099	+	DDB_G0284191	DDB_G0284191	NA
chr4	1673200	1674670	+	DDB_G0284193	DDB_G0284193	NA
chr4	1675652	1675709	-	DDB_G0295587	r24B	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	1675966	1676021	+	DDB_G0295589	r54	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	1676837	1679614	-	DDB_G0284195	DDB_G0284195	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0284195 is highly similar in the upstream half to cofactor of BRAC1%2C also known as COBRA1%2C which in mammals participates in a four-protein complex called NELF (negative elongation factor). NELF negatively regulates steroid-hormone induced gene regulation. Candidates for other components of the NELF complex are found in Dicty%3B DDB_G0268678 is a clear NELF C%2FD subunit%3B DDB_G0286295 is a possible NELF A subunit%3B DDB_G0276985 is a possible NELF RDBP subunit. Recent work shows that NELF participates in 3%27 end processing of histone mRNAs in association with the SLBP%3B see Narita et al%2C Mol. Cell 26%2C 349-365 (2007).%3Cbr%3E DDB G0284195 is strongly (12-fold)overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). Most genes with known roles in S-phase or mitosis are overexpressed in this strain. Several other proteins involved in histone mRNA processing are upregulated in the rblA disruptant%3B these include DDB_G0288225 (histone stem loop binding protein)%2C DDB_G0277383 (similar to histone stem-loop binding protein) and eriA. It is thus plausible that DDB_G0284195%2FCOBRA1 is involved in histone mRNA processing in Dictyostelium. %3Ci%3EHarry MacWilliams%2C November 2009%3C%2Fi%3E
chr4	1680128	1681774	+	DDB_G0284197	proS	catalyzes the reaction ATP %2B L-proline %2B tRNAPro %3D AMP %2B diphosphate %2B L-prolyl-tRNAPro
chr4	1682534	1683645	-	DDB_G0284199	DDB_G0284199	contains a predicted signal sequence%3B similar to D. purpureum protein
chr4	1684869	1685329	+	DDB_G0284201	DDB_G0284201	very similar to RNA polymerase II transcription factor SIII subunit C%2C elongin C%2C or transcription elongation factor B polypeptide 1 (TCEB1)
chr4	1685557	1686979	-	DDB_G0284203	kynu	catalyzes the reaction L-kynurenine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E anthranilate %2B L-alanine during nicotinic acid biosynthesis
chr4	1687407	1687951	-	DDB_G0284205	ubl5	ortholog of human UBL5 and yeast HUB1%3B human UBL5 interacts with cyclin-dependent kinase CLK4
chr4	1688943	1690025	+	DDB_G0284207	DDB_G0284207	NA
chr4	1690478	1691446	-	DDB_G0284209	DDB_G0284209	NA
chr4	1692886	1693841	+	DDB_G0284211	DDB_G0284211_ps	putative pseudogene belonging to the short-chain dehydrogenase%2Freductase (SDR) family%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E probably a recent pseudogene of the short-chain dehydrogenase family including DDB0185894. The coding sequence share high level of homology with DDB0185894 before and after the stop codon%2C resulting in a truncated and probably non functional protein if that gene is still transcribed. %3Ci%3EChristophe Anjard May 2007%3C%2Fi%3E
chr4	1693957	1696537	-	DDB_G0284213	DDB_G0284213	NA
chr4	1697612	1699450	-	DDB_G0284181	krsA	putative protein serine%2Fthreonine kinase%3B belongs to the protein kinase MST subfamily%3B similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B stress-responsive kinase%3B involved in signal transduction and hyperosmotic response
chr4	1700271	1701885	-	DDB_G0284217	DDB_G0284217	similar to H. sapiens CNOT7 and CNOT8 and S. cerevisiae POP2%2C which are components of the CCR4-NOT transcription complex
chr4	1702610	1704995	-	DDB_G0284219	ase1B	member of the MAP65%2FASE1 family of microtubule associated proteins%3B ortholog of human PRC1 and yeast ASE1
chr4	1705613	1706032	-	DDB_G0284221	atox1	ortholog of the conserved copper chaperone ATOX1 (Mammals) and ATX1 (yeast)
chr4	1707062	1708958	+	DDB_G0284307	DDB_G0284307	conserved ortholog mammalian CAB39 (calcium-binding protein 39) and S. pombe Mo25%2C involved in cytokinesis 
chr4	1711370	1712269	+	DDB_G0284311	DDB_G0284311	NA
chr4	1712491	1714131	-	DDB_G0284223	DDB_G0284223	NA
chr4	1714783	1716647	+	DDB_G0284225	ucpC	ortholog of slc25a11%3B catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids%3B plays a role in several metabolic processes%2C such as the malate-aspartate shuttle%2C the oxoglutarate%2Fisocitrate shuttle%2C in gluconeogenesis from lactate%2C and in nitrogen metabolism
chr4	1717119	1721366	+	DDB_G0284227	DDB_G0284227	NA
chr4	1721453	1721674	-	DDB_G0284229	DDB_G0284229	NA
chr4	1721739	1722697	-	DDB_G0284231	DDB_G0284231	NA
chr4	1723068	1723329	+	DDB_G0284233	DDB_G0284233	NA
chr4	1723675	1725068	-	DDB_G0284235	DDB_G0284235	NA
chr4	1725990	1727775	-	DDB_G0284313	tbcC	NA
chr4	1728697	1729626	+	DDB_G0284315	DDB_G0284315	contains 6 putative transmembrane domains%3B similar to D. purpureum protein
chr4	1729814	1730224	-	DDB_G0284237	rps12	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S12 homolog
chr4	1731488	1733684	+	DDB_G0284239	DDB_G0284239	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages
chr4	1733961	1735439	+	DDB_G0284241	DDB_G0284241	ortholog of mammalian pcid2 and yeast CSN12
chr4	1735866	1737435	-	DDB_G0284243	DDB_G0284243	similar to yeast PTC1%2C type 2C protein phosphatase (PP2C)%2C which is involved in mitochondrial inheritance%2C tRNA splicing%2C sporulation%2C and cell separation
chr4	1740402	1740908	+	DDB_G0284317	sigD_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0267474%22%3E%3Ci%3EsigD%3C%2Fi%3E%3C%2Fa%3E
chr4	1741477	1746822	+	DDB_G0284319	sympk	in mammals%2C symplekin is a component of the tight junction plaque%2C but has also been detected in a wide range of cell types that do not form tight junctions%3B may be required for pre-mRNA polyadenylation
chr4	1747466	1748910	-	DDB_G0284245	DDB_G0284245	contains a single%2C N-terminal RRM domain%2C which is similar to those in human splicing factors%2C arginine%2Fserine-rich%2C such as SFRS4 and SFRS6%2C however%2C these proteins contain two N-terminal RRM domains
chr4	1749570	1751523	+	DDB_G0284247	DDB_G0284247	NA
chr4	1751734	1754028	-	DDB_G0284249	DDB_G0284249	putative metalloprotease of the peptidase M41 family%2C which belong to a larger family of zinc metalloproteases%3B includes the cell division protein FtsH%2C and the yeast mitochondrial respiratory chain complexes assembly protein
chr4	1754346	1756247	-	DDB_G0284251	DDB_G0284251	kinase domain similar to those of mitogen-activated protein kinases%3B similar to the STE20 family
chr4	1758153	1759359	-	DDB_G0284253	DDB_G0284253	similar to human EI24 (etoposide-induced protein 2.4 homolog) which may play a role in the cellular response to DNA damage and%2For p53-mediated apoptosis%3B contains 6 putative transmembrane domains
chr4	1760065	1764027	+	DDB_G0284321	DDB_G0284321	similar to PTBP1%2C PTB2%2C and ROD1%2C heterogeneous ribonucleoproteins that play a role in pre-mRNA splicing
chr4	1777902	1780775	+	DDB_G0284255	DDB_G0284255	NA
chr4	1781348	1782846	-	DDB_G0284257	dph1	ortholog to the conserved DPH1%2C which in %3Ci%3ES. cerevisiae%3C%2Fi%3E is required for synthesis of diphthamide%2C a modified histidine residue of translation elongation factor 2
chr4	1783122	1785177	+	DDB_G0284323	ppil2	peptidyl-prolyl cis-trans isomerase (PPIase) accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr4	1785353	1787081	+	DDB_G0294595	DDB_G0294595	multi-domain protein%3B the TPR superhelical structures present a surface that is well suited to binding large substrates such as proteins and nucleic acids
chr4	1787150	1790086	-	DDB_G0284259	DDB_G0284259	NA
chr4	1791019	1791714	+	DDB_G0284185	syn6	similar to syntaxin%2C a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr4	1792427	1792983	+	DDB_G0284303	DDB_G0284303	NA
chr4	1793617	1795080	+	DDB_G0284261	nxnB	type I annexins inhibit phospholipase A2 following dephosphorylation by protein kinases involved in the signal transduction pathway%3B may also associate with the cell cytoskeleton by binding to F-actin
chr4	1795281	1797504	-	DDB_G0284263	DDB_G0284263	conserved protein%2C ortholog of human DNAJC11
chr4	1798190	1799209	+	DDB_G0284265	ppa1	inorganic pyrophosphatase 1 (PPAse)%3B cytoplasmic enzyme in yeast IPP1%2C catalyzes the rapid exchange of oxygens from Pi with water
chr4	1799493	1801319	-	DDB_G0284267	eIF2a	EIF2A ortholog%2C the eukaryotic initiation factor 2A that binds Met-tRNA
chr4	1802373	1802445	-	DDB_G0295229	tRNA-Lys-UUU-15	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr4	1803929	1804443	+	DDB_G0284269	DDB_G0284269	NA
chr4	1804849	1806154	+	DDB_G0284271	DDB_G0284271_ps	putative pseudogene%3B fragment%2C similar to EGF repeat-containing proteins %3Ca href%3D%22%2Fgene%2FDDB_G0277431%22%3EDDB_G0277431%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0277525%22%3EDDB_G0277525%3C%2Fa%3E
chr4	1806777	1808384	+	DDB_G0284273	DDB_G0284273	NA
chr4	1809449	1811827	+	DDB_G0284325	DDB_G0284325	NA
chr4	1812405	1813706	+	DDB_G0284327	tmem184F	TMEM184 family protein%3B the long splice variant contains 6 putative transmembrane domains and an additional signal sequence%2C the short splice variant contains 4 putative transmembrane domains
chr4	1813905	1819443	-	DDB_G0284187	Dd5P2	NA
chr4	1820423	1821487	+	DDB_G0284275	DDB_G0284275	NA
chr4	1821556	1822490	-	DDB_G0284277	DDB_G0284277	similar to bacterial short-chain dehydrogenase%2Freductase family proteins
chr4	1822941	1826285	-	DDB_G0284279	DDB_G0284279_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0276559%22%3EDDB_G0276559%3C%2Fa%3E
chr4	1827185	1830211	-	DDB_G0284281	DDB_G0284281	NA
chr4	1832487	1832739	+	DDB_G0284283	DDB_G0284283	NA
chr4	1833130	1833907	+	DDB_G0284285	DDB_G0284285	NA
chr4	1834114	1834675	-	DDB_G0284287	DDB_G0284287	NA
chr4	1835474	1837830	-	DDB_G0284289	DDB_G0284289	NA
chr4	1839037	1839336	-	DDB_G0284291	gatC	catalyzes the reaction ATP %2B L-glutamyl-tRNA(Gln) %2B L-glutamine %3D ADP %2B phosphate %2B L-glutaminyl-tRNA(Gln) %2B L-glutamate
chr4	1841189	1843317	+	DDB_G0284293	hbx10	NA
chr4	1844275	1845881	+	DDB_G0284295	iliG	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr4	1846274	1849299	-	DDB_G0284183	mrfA	regulates gene expression in pstA cells%3B ortholog of mouse myelin-gene transcription factor
chr4	1851676	1855620	+	DDB_G0284337	cynA	localizes to the cell lagging edge%3B contributes to the establishment of the cell axis
chr4	1855900	1856883	+	DDB_G0284339	aplN	contains three saposin B domains
chr4	1857300	1858168	+	DDB_G0284341	lyrm5	belongs to a family of short proteins that includes ndufa6 from the NADH-ubiquinone oxidoreductase complex I%3B named LYR after a highly conserved tripeptide motif
chr4	1858931	1860087	+	DDB_G0284443	DDB_G0284443	NA
chr4	1860277	1861465	-	DDB_G0284343	DDB_G0284343	NA
chr4	1862286	1864421	+	DDB_G0284345	cyp556A1	NA
chr4	1865073	1866634	+	DDB_G0284347	vps4	putative ESCRT-associated protein (endosomal sorting complex required for transport)
chr4	1866926	1868766	-	DDB_G0284349	gdap2	ortholog of the human GDAP2 protein%3B contains an Appr-1-p processing domain and a C-terminal cellular retinaldehyde-binding%2Ftriple function domain
chr4	1869385	1870278	+	DDB_G0284351	DDB_G0284351	NA
chr4	1870805	1872192	-	DDB_G0284353	osbI	NA
chr4	1873789	1875934	+	DDB_G0284355	DDB_G0284355	NA
chr4	1876303	1878098	+	DDB_G0284449	plbD	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276767%22%3E%3Ci%3EplbA%3C%2Fi%3E%3C%2Fa%3E%2C which catalyzes the hydrolysis of phosphatidylcholine to glycerophosphocholine
chr4	1878838	1879515	-	DDB_G0284445	DDB_G0284445_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr4	1879566	1879638	+	DDB_G0295169	tRNA-Ile-AAU-10	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr4	1880019	1881063	+	DDB_G0284451	DDB_G0284451_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0268494%22%3EDDB_G0268494%3C%2Fa%3E 
chr4	1881383	1883622	-	DDB_G0284357	dduE	underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants%3B downregulated in the uninfected %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr4	1884053	1885252	-	DDB_G0284359	phaZ	similar to PHB depolymerase%2C which catalyzes the reaction: H2O %2B poly[(R)-3-hydroxybutanoate](n) %3D poly[(R)-3-hydroxybutanoate](x) %2B poly[(R)-3-hydroxybutanoate](n-x)%3B where x is between 1 and 5 units%3B polyhydroxyalkanoates (PHAs) are typical storage compounds of carbon and energy and are widely found in prokaryotes %3B the most common PHA is poly(3-hydroxybutyrate) (PHB)
chr4	1885441	1887301	-	DDB_G0284335	sslA1	mutation in the sslA1 gene increases the fruiting body size of smlA mutants%3B positively regulates group size%3B there is an identical gene on chromosome 3%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0278309%22%3E%3Ci%3EsslA2%3C%2Fi%3E%3C%2Fa%3E
chr4	1888546	1892124	-	DDB_G0284361	DDB_G0284361	NA
chr4	1892663	1894210	-	DDB_G0284363	cf60	regulates aggregate size and number%3B component of the counting factor complex%2C which includes CF60%2C CF50%2C CF45-1%2C and CtnA (countin)%3B similar to histidine acid phosphatase but does not possess phosphatase activity
chr4	1895020	1895769	+	DDB_G0284365	DDB_G0284365	NA
chr4	1896160	1897120	-	DDB_G0284367	DDB_G0284367	NA
chr4	1898347	1899583	-	DDB_G0284369	DDB_G0284369	NA
chr4	1900513	1901488	+	DDB_G0284371	DDB_G0284371	NA
chr4	1901736	1902909	-	DDB_G0284373	DDB_G0284373	NA
chr4	1903726	1904903	-	DDB_G0284453	DDB_G0284453	NA
chr4	1905434	1906586	-	DDB_G0284375	DDB_G0284375	NA
chr4	1906991	1909198	-	DDB_G0284455	DDB_G0284455	NA
chr4	1910380	1912062	+	DDB_G0284377	DDB_G0284377	contains 12 putative transmembrane domains
chr4	1912156	1915705	-	DDB_G0284379	xpo5	ortholog of H. sapiens XPO5 and S. cerevisiae MSN5 (Multicopy Suppressor of SNF1 mutation) involved in protein export from nucleus
chr4	1916862	1920131	+	DDB_G0284381	DDB_G0284381	similar to mammalian USP4
chr4	1920700	1923303	+	DDB_G0284383	DDB_G0284383	NA
chr4	1923544	1924484	-	DDB_G0284385	syn10	similar to syntaxin%2C a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr4	1926792	1928739	+	DDB_G0284329	gefA	guanine nucleotide exchange factor for RasC%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form%3B  required for adenylyl cyclase activation
chr4	1929000	1932341	+	DDB_G0284387	DDB_G0284387	NA
chr4	1932445	1935469	-	DDB_G0284389	fia	composed of a DUF292 domain at the amino terminus%2C two filamin%2FABP280 repeats and an actin domain at the carboxyl terminus
chr4	1935986	1938051	-	DDB_G0284391	DDB_G0284391	catalyzes the hydrolysis of the terminal 1%2C2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2%3B some members of this family are responsible for protein N-linked glycosylation%2C while other participate in the degradation of misfolded glycoproteins in the endoplasmic reticulum
chr4	1939162	1940857	-	DDB_G0284393	DDB_G0284393	catalyzes the hydrolysis of the terminal 1%2C2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2%3B some members of this family are responsible for protein N-linked glycosylation%2C while other participate in the degradation of misfolded glycoproteins in the endoplasmic reticulum
chr4	1942017	1943832	-	DDB_G0284395	DDB_G0284395	catalyzes the hydrolysis of the terminal 1%2C2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2%3B some members of this family are responsible for protein N-linked glycosylation%2C while other participate in the degradation of misfolded glycoproteins in the endoplasmic reticulum
chr4	1944417	1945923	-	DDB_G0284397	DDB_G0284397	NA
chr4	1946519	1950085	-	DDB_G0284333	lvsF	similar to mammalian FAN%2C human LYST%2C and mouse Beige proteins
chr4	1950553	1952517	+	DDB_G0284399	mybY	contains one Myb DNA-binding domain
chr4	1952708	1953586	-	DDB_G0284401	DDB_G0284401	conserved hypothetical Dictyostelium protein%3B similar to bacterial ubiquinone%2Fmenaquinone biosynthesis methyltransferase ubiE
chr4	1954324	1955003	-	DDB_G0284403	phf5a	subunit of the splicing factor SF3B required for spliceosome assembly
chr4	1955406	1956629	+	DDB_G0284405	mrpl15	protein component of the mitochondrial large ribosomal subunit
chr4	1956975	1959735	-	DDB_G0284331	regA	contains a 3%275%27-cyclic nucleotide phosphodiesterase and a response regulator receiver domain found in two-component signal transduction systems
chr4	1962362	1963750	+	DDB_G0284407	erg24	catalyzes the reaction 4%2C4-dimethyl-5-alpha-cholesta-8%2C24-dien-3-beta-ol %2B NADP(%2B) %3D 4%2C4-dimethyl-5-alpha-cholesta-8%2C14%2C24-trien-3-beta-ol %2B NADPH
chr4	1964242	1964945	+	DDB_G0284409	iliB	induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr4	1965235	1966608	+	DDB_G0284411	dng1	similar to inhibitor of growth family (ING) proteins
chr4	1967001	1967573	+	DDB_G0284413	DDB_G0284413	NA
chr4	1968066	1969603	+	DDB_G0284415	psmC3	ATPase subunit of the regulatory subcomplex of the 26S proteasome
chr4	1971161	1974139	+	DDB_G0284419	xpf	ortholog of H. sapiens ERCC4 and S. cerevisiae RAD1 nucleotide excision repair genes%3B involved in DNA double-strand repair by homologous recombination
chr4	1974366	1975576	+	DDB_G0284457	DDB_G0284457	NA
chr4	1975693	1976671	-	DDB_G0284421	med6	ortholog of the mediator of RNA polymerase II transcription subunit 6%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr4	1976888	1978185	+	DDB_G0284423	DDB_G0284423	NA
chr4	1978561	1978800	+	DDB_G0284425	DDB_G0284425	NA
chr4	1979111	1980534	-	DDB_G0284427	DDB_G0284427	contains a predicted signal peptide and a putative C-terminal transmembrane domain
chr4	1981059	1981922	-	DDB_G0284429	DDB_G0284429	NA
chr4	1983105	1983854	-	DDB_G0284431	udpA	catalyzes the reaction phosphate %2B uridine %3C%3D%3E ribose-1-phosphate %2B uracil in salvage pathways of pyrimidine ribonucleotides and deoxyribose phosphate degradation
chr4	1985042	1986076	+	DDB_G0284433	DDB_G0284433	NA
chr4	1986677	1990587	+	DDB_G0284459	DDB_G0284459	NA
chr4	1990910	1992815	+	DDB_G0284435	pigB	CAZy family GT22%3B catalyzes the addition of the third mannose to GPI (glycosylphosphatidylinositol)
chr4	1993267	1994253	+	DDB_G0284437	DDB_G0284437	NA
chr4	1994656	1997578	+	DDB_G0284439	DDB_G0284439	NA
chr4	1997677	2000181	-	DDB_G0284441	DDB_G0284441	NA
chr4	2003252	2005552	-	DDB_G0284461	DDB_G0284461	contains a C2 domain believed to be involved in calcium-dependent phospholipid binding and eight LRRs
chr4	2005913	2007284	-	DDB_G0284463	maea	ortholog of the mammalian MAEA protein that mediates the attachment of erythroblasts to macrophages
chr4	2008237	2008455	+	DDB_G0284547	DDB_G0284547	NA
chr4	2010250	2017993	-	DDB_G0284475	DDB_G0284475	NA
chr4	2018714	2021851	+	DDB_G0284477	DDB_G0284477	NA
chr4	2022587	2023366	+	DDB_G0284479	DDB_G0284479	NA
chr4	2024271	2025047	+	DDB_G0284549	dduF	contains a predicted signal peptide (cleavage site not optimal)%3B downregulated in the uninfected %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr4	2025823	2026718	+	DDB_G0284541	DDB_G0284541	NA
chr4	2027462	2030822	+	DDB_G0284481	DDB_G0284481	NA
chr4	2030962	2034452	-	DDB_G0284483	ints7	ortholog of integrator complex subunit 7%2C component of a multiprotein mediator of small nuclear RNA processing
chr4	2034779	2035915	-	DDB_G0284485	DDB_G0284485	NA
chr4	2036413	2037999	+	DDB_G0284487	DDB_G0284487	NA
chr4	2038480	2041297	+	DDB_G0284489	pdkB	member of the AGC kinase group%3B similar to mammalian PDK (phosphoinositide-dependent protein kinase) known to phosphorylate Akt%2FPKB
chr4	2041403	2045127	-	DDB_G0284491	DDB_G0284491	NA
chr4	2045896	2047208	+	DDB_G0284493	DDB_G0284493	NA
chr4	2047442	2049155	-	DDB_G0284495	ragC	ortholog of S. cerevisiae GTR2 and H. sapiens RagC%2C a cytoplasmic GTP binding protein
chr4	2050510	2051124	+	DDB_G0284497	DDB_G0284497	NA
chr4	2051268	2054927	-	DDB_G0284499	smc2	functions in chromosome dynamics%3B heterodimerizes with smc4
chr4	2055453	2056850	-	DDB_G0284551	fut4	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr4	2058245	2061757	+	DDB_G0284501	gxcQ	NA
chr4	2061934	2063304	-	DDB_G0284553	gmd	catalyzes the reaction GDP-mannose %3C%3D%3E GDP-4-dehydro-6-deoxy-D-mannose %2B H%3Csub%3E2%3C%2Fsub%3EO
chr4	2064096	2065487	+	DDB_G0284503	fut6	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr4	2066316	2067704	+	DDB_G0284505	fut5	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr4	2068357	2070234	+	DDB_G0284555	sf3b2	subunit of the splicing factor SF3B required for spliceosome assembly
chr4	2070281	2071515	-	DDB_G0284507	DDB_G0284507	putative ortholog of Rad51C%2C which is involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks%3B interacts with XRCC3
chr4	2071986	2072320	-	DDB_G0348374	DDB_G0348374	NA
chr4	2073118	2073330	-	DDB_G0348373	DDB_G0348373	NA
chr4	2077506	2078422	+	DDB_G0284511	DDB_G0284511	NA
chr4	2079840	2084303	+	DDB_G0284513	DDB_G0284513	NA
chr4	2085226	2086826	+	DDB_G0284515	DDB_G0284515	NA
chr4	2087340	2089701	+	DDB_G0284545	sgkB	homolog of human Sphk2%3B phosphorylates sphinganine to sphinganine 1-phosphate
chr4	2090141	2091556	+	DDB_G0284517	psmC6	ATPase subunit and regulatory subcomplex of the 26S proteasome
chr4	2091815	2094223	-	DDB_G0284465	cudA	required for culmination%3B expressed in prespore and pstA cells%3B exists as a homodimer
chr4	2097497	2100503	+	DDB_G0284519	forI	contains an actin-binding FH2 (formin homology 2) domain
chr4	2100599	2101369	-	DDB_G0284521	DDB_G0284521	NA
chr4	2102761	2103650	+	DDB_G0284523	DDB_G0284523	NA
chr4	2103969	2109805	-	DDB_G0284471	kif8	contains 7 WD40 repeats
chr4	2110678	2111280	+	DDB_G0284557	DDB_G0284557	catalyzes the reaction ATP %2B D-gluconate %3C%3D%3E ADP %2B 6-phospho-D-gluconate
chr4	2111778	2113587	-	DDB_G0284525	tmem184A	similar to H. sapiens TMEM184A and B%3B contains 7 predicted transmembrane domains
chr4	2115024	2116681	-	DDB_G0284527	DDB_G0284527	NA
chr4	2118136	2119774	-	DDB_G0284529	DDB_G0284529	NA
chr4	2120826	2121437	-	DDB_G0284531	DDB_G0284531	NA
chr4	2123220	2124500	+	DDB_G0284559	DDB_G0284559	NA
chr4	2125012	2126419	+	DDB_G0284467	fut1	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr4	2127182	2127908	-	DDB_G0284533	rps13	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S13 homolog
chr4	2128349	2129813	-	DDB_G0284469	gpaH	subunit of the heterotrimeric G protein that has GTPase activity
chr4	2131768	2134716	+	DDB_G0284561	DDB_G0284561	NA
chr4	2134830	2136505	-	DDB_G0284563	cwc2	similar to %3Ci%3ES. pombe%3C%2Fi%3E and %3Ci%3E S. cerevisiae%3C%2Fi%3E CWC2%2C which are involved in pre-mRNA splicing
chr4	2137636	2139414	+	DDB_G0284535	cyp508A4	NA
chr4	2139831	2140908	-	DDB_G0284537	DDB_G0284537	NA
chr4	2142583	2147590	-	DDB_G0284565	DDB_G0284565	NA
chr4	2149008	2151203	-	DDB_G0284473	vatC	ortholog of the C subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the C subunit is part of the V1 subunit
chr4	2152696	2155778	-	DDB_G0284539	DDB_G0284539	NA
chr4	2159197	2161333	+	DDB_G0284567	gnt14	CAZy family GT49%3B similar to vertebrate acetylglucosaminyltransferase-like protein
chr4	2163129	2166028	+	DDB_G0284579	DDB_G0284579	contains 12 putative transmembrane domains
chr4	2167100	2169809	+	DDB_G0284569	DDB_G0284569	NA
chr4	2170033	2171619	-	DDB_G0284571	gacC	NA
chr4	2172315	2173545	+	DDB_G0284573	syf2	%3Ci%3ED. discoideum%3C%2Fi%3E SYF2 homolog%3B SYF2 proteins are involved in cell cycle progression and pre-mRNA splicing
chr4	2173651	2175465	-	DDB_G0284575	DDB_G0284575	NA
chr4	2176004	2178172	-	DDB_G0284577	DDB_G0284577	putative ortholog of H. sapiens CNOT2 and S. cerevisiae CDC36%3B component of the CCR4-NOT transcription complex
chr4	2178851	2179736	+	DDB_G0284589	dlcA	dynein is a multisubunit microtubule-dependent motor enzyme that acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules%3B belongs to the T-complex testis-specific protein 1 family
chr4	2180042	2181240	+	DDB_G0284581	DDB_G0284581	NA
chr4	2181616	2183756	+	DDB_G0284583	glyS	catalyzes the reaction ATP %2B glycine %2B tRNAGly %3D AMP %2B diphosphate %2B glycyl-tRNAGly
chr4	2184288	2186464	+	DDB_G0284585	fslL	similar to the G-protein coupled receptors%3B contains 7 putative transmembrane domains and a potential signal sequence
chr4	2187151	2188593	+	DDB_G0284587	DDB_G0284587	NA
chr4	2189321	2193096	-	DDB_G0284591	DDB_G0284591	NA
chr4	2205667	2207051	-	DDB_G0284597	csn5	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8) 
chr4	2207693	2209243	+	DDB_G0284599	DDB_G0284599	similar to human RNF38 (RING finger protein 38)
chr4	2209637	2210617	-	DDB_G0284601	csnk2b	ortholog of the CK2 beta chain%2C the regulatory subunit of the ubiquitious serine%2Fthreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to casein
chr4	2211789	2213620	+	DDB_G0284603	DDB_G0284603	NA
chr4	2214347	2217243	+	DDB_G0284605	DDB_G0284605	conserved plasma membrane calcium ATPases (PMCA)%2C similar to %3Ci%3EDictyostelium%3C%2Fi%3E PAT1%3B contains 10 predicted transmembrane domains
chr4	2220197	2220277	-	DDB_G0295227	tRNA-Ser-GCU-11	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr4	2220278	2221002	+	DDB_G0284609	DDB_G0284609_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr4	2227631	2227711	+	DDB_G0295171	tRNA-Ser-GCU-10	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr4	2228341	2233365	+	DDB_G0284615	DDB_G0284615	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr4	2233409	2235120	-	DDB_G0284617	DDB_G0284617	contains a weak RimK-like ATP-grasp domain%2C which is found in the ribosomal S6 modification enzyme RimK
chr4	2237635	2238396	-	DDB_G0284619	DDB_G0284619	NA
chr4	2240813	2244334	-	DDB_G0284621	pwp2	ortholog of H. sapiens and S. cerevisiae PWP2 involved in the endonucleolytic cleavage of the 35 S rRNA precursor
chr4	2245895	2247689	+	DDB_G0284719	med29	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 29 (metazoa) or 2 (fungi)%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr4	2252387	2254660	+	DDB_G0284721	DDB_G0284721	NA
chr4	2255880	2256178	-	DDB_G0284623	DDB_G0284623	NA
chr4	2257074	2259740	-	DDB_G0284625	DDB_G0284625	conserved hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E protein%2C contains one EGF-like%2C type 3 domain
chr4	2260399	2261655	-	DDB_G0284627	DDB_G0284627	belongs to the band 7 proteins%2C integral membrane proteins that ares thought to regulate cation conductance%3B stomatin is an erythrocyte membrane protein%3B contains an N-terminal transmembrane domain that might be a signal sequence
chr4	2262832	2263274	+	DDB_G0284629	DDB_G0284629	conserved in Dictyostelids%3B predicted to have structural similarity to the NFT2-like superfamily (nuclear transport factor)%3B there is a highly similar gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0284631%22%3E%3Ci%3EDDB_G0284631%3C%2Fi%3E%3C%2Fa%3E%2C downstream
chr4	2263474	2263921	-	DDB_G0284631	DDB_G0284631	conserved in Dictyostelids%3B predicted to have structural similarity to the NFT2-like superfamily (nuclear transport factor)%3B there is a highly similar gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0284629%22%3E%3Ci%3EDDB_G0284629%3C%2Fi%3E%3C%2Fa%3E%2C upstream
chr4	2264683	2266959	+	DDB_G0284633	DDB_G0284633	NA
chr4	2267233	2267532	-	DDB_G0284635	DDB_G0284635	NA
chr4	2269967	2271619	+	DDB_G0284637	DDB_G0284637	NA
chr4	2272052	2273707	+	DDB_G0284639	DDB_G0284639_ps	putative pseudogene%3B nearly identical to the upstream %3Ca href%3D%22%2Fgene%2FDDB_G0284637%22%3EDDB_G0284637%3C%2Fa%3E
chr4	2274398	2274878	+	DDB_G0284641	DDB_G0284641	NA
chr4	2275277	2278014	-	DDB_G0284613	D7	NA
chr4	2279720	2280877	+	DDB_G0284643	DDB_G0284643	NA
chr4	2281332	2282094	-	DDB_G0284645	DDB_G0284645	NA
chr4	2282608	2285067	-	DDB_G0294563	DDB_G0294563	EGF domain similar to the EGF-like repeats found in subtilisin-like serine peptidase%2C tenascin X%2C and WIF (Wnt inhibitory factor)
chr4	2285672	2287360	-	DDB_G0284647	cyp517A2	NA
chr4	2287653	2289871	-	DDB_G0284649	DDB_G0284649	similar to D. purpureum protein
chr4	2291954	2294131	+	DDB_G0284651	gcsA	catalyzes the reaction ATP %2B L-glutamate %2B L-cysteine %3D ADP %2B phosphate %2B gamma-L-glutamyl-L-cysteine%2C the first and limiting step in glutathione (GSH) biosynthesis
chr4	2294408	2295991	-	DDB_G0284655	DDB_G0284655_ps	putative pseudogene%3B similar to the large D. discoideum family of FNIP repeat-containing proteins
chr4	2297325	2303099	+	DDB_G0284725	docD	belongs to the Dock180 family%3B contains an SH3 domain
chr4	2303787	2306087	+	DDB_G0284657	DDB_G0284657	NA
chr4	2306298	2308594	-	DDB_G0284659	tgrL1	contains a predicted signal peptide
chr4	2309177	2310808	-	DDB_G0284661	DDB_G0284661	putative protein serine%2Fthreonine kinase CAMK group%3B kinase domain similar to mammalian CAM kinase I
chr4	2313169	2315723	+	DDB_G0284727	DDB_G0284727	NA
chr4	2315842	2318657	-	DDB_G0284663	mrd1	ortholog of yeast MRD1 and mammalian RBM19%3B yeast MRD1 binds to the 35S pre-rRNA and the U3 snoRNA and is involved in pre-rRNA processing%3B contains 5 RRM domains
chr4	2318999	2319516	-	DDB_G0284665	DDB_G0284665	NA
chr4	2319957	2320799	+	DDB_G0284667	pigF	involved in GPI biosynthesis%3B functions with PigO to transfer ethanolamine phosphate to the third mannose of GPI (glycosylphosphatidylinositol)
chr4	2322296	2323334	+	DDB_G0284669	prsA	ortholog of PRS%2C involved in nucleotide%2C histidine%2C and tryptophan biosynthesis
chr4	2323961	2325047	+	DDB_G0284671	DDB_G0284671	serine-rich protein with no conserved functional domains
chr4	2325423	2325716	-	DDB_G0284673	DDB_G0284673_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0284675%22%3EDDB_G0284675%3C%2Fa%3E 
chr4	2326080	2327024	-	DDB_G0284675	DDB_G0284675	contains a predicted signal peptide
chr4	2327899	2330183	+	DDB_G0284729	fslK	similar to G-protein-coupled receptors%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr4	2331829	2333137	+	DDB_G0284677	expl2	similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B contains a predicted signal peptide 
chr4	2333236	2334456	-	DDB_G0284679	nse3	NA
chr4	2334842	2335972	+	DDB_G0284681	DDB_G0284681	contains 2 SCP2 (sterol carrier protein) domains%3B contains a predicted peroxisomal targeting signal
chr4	2336209	2339112	-	DDB_G0284683	DDB_G0284683	NA
chr4	2341606	2343049	-	DDB_G0284685	mpi	catalyzes the reaction D-Mannose 6-phosphate %3C%3D%3E D-fructose 6-phosphate
chr4	2343826	2345747	+	DDB_G0284687	DDB_G0284687	similar to protozoan and bacterial cardiolipin synthetases%3B contains two PLDc domains
chr4	2346926	2349655	+	DDB_G0284611	ripA	component of the TORC2 (Tor complex 2) with Tor%2C Lst8%2C and PiaA that plays a role in regulation of adenylate cyclase (ACA) and protein kinase B (PKB) activation during aggregation
chr4	2350414	2355543	+	DDB_G0284689	DDB_G0284689	NA
chr4	2357079	2358174	+	DDB_G0284691	DDB_G0284691	NA
chr4	2358649	2359022	-	DDB_G0284693	DDB_G0284693	homolog of human COX6B1 and S. cerevisiae COX12%3B this protein is one of the polypeptide chains of cytochrome c oxidase%2C the terminal oxidase in mitochondrial electron transport
chr4	2359622	2360974	-	DDB_G0284695	DDB_G0284695	NA
chr4	2361299	2362276	+	DDB_G0284697	hemC	catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane in heme biosynthesis
chr4	2362420	2366575	-	DDB_G0284699	mtr	multifunctional folate synthesis enzyme%3B catlayzes the reaction 5-methyltetrahydrofolate %2B L-homocysteine %3D tetrahydrofolate %2B L-methionine.
chr4	2369310	2371160	+	DDB_G0295719	DDB_G0295719	contains a putative signal sequence
chr4	2371416	2372808	-	DDB_G0284701	DDB_G0284701	mandelate racemase (EC:5.1.2.2) and muconate lactonizing enzyme (EC:5.5.1.1) are two bacterial enzymes involved in aromatic acid catabolism.
chr4	2373104	2375772	-	DDB_G0295717	DDB_G0295717	similar to TBC1 domain family member GTPase-activating proteins
chr4	2376164	2378598	-	DDB_G0284713	polB	similar to yeast Pol4 and mammalian DNA polymerase beta%3B involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ)
chr4	2378839	2380249	-	DDB_G0284705	DDB_G0284705	NA
chr4	2380797	2383385	+	DDB_G0284731	DDB_G0284731	NA
chr4	2388566	2389651	+	DDB_G0284707	DDB_G0284707	belongs to a gene family conserved in amoeba%3B similar to bacterial pentalenene synthase%3B contains a putative metal-binding domain
chr4	2390943	2391173	-	DDB_G0284733	DDB_G0284733_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr4	2392075	2393759	-	DDB_G0284829	DDB_G0284829_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr4	2394561	2397811	+	DDB_G0284735	copB	beta subunit of the coatomer complex essential for the secretory pathway%3B colocalizes with comitin at the Golgi
chr4	2397942	2398964	-	DDB_G0284737	DDB_G0284737	belongs to the haloacid dehalogenase (HAD) hydrolase IIA family%3B similar to human PGP (phosphoglycolate phosphatase) and S. cerevisiae PHO13 (4-nitrophenylphosphatase)
chr4	2399480	2401787	-	DDB_G0284739	gxcFF	NA
chr4	2402392	2406579	-	DDB_G0284741	DDB_G0284741	NA
chr4	2409764	2411508	-	DDB_G0284743	4cl3	catalyzes the reaction ATP %2B 4-coumarate %2B CoA %3D AMP %2B diphosphate %2B 4-coumaroyl-CoA
chr4	2413291	2415024	-	DDB_G0284745	4cl2	catalyzes the reaction ATP %2B 4-coumarate %2B CoA %3D AMP %2B diphosphate %2B 4-coumaroyl-CoA
chr4	2416042	2417784	-	DDB_G0284831	4cl1	catalyzes the reaction ATP %2B 4-coumarate %2B CoA %3D AMP %2B diphosphate %2B 4-coumaroyl-CoA
chr4	2418843	2422835	-	DDB_G0284833	exoc4	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr4	2423376	2426473	-	DDB_G0284747	msh5	NA
chr4	2426750	2430729	-	DDB_G0284749	DDB_G0284749	NA
chr4	2431735	2432895	+	DDB_G0284751	DDB_G0284751	NA
chr4	2432933	2434591	-	DDB_G0284753	DDB_G0284753	NA
chr4	2435039	2436644	-	DDB_G0284755	DDB_G0284755	NA
chr4	2437158	2439674	-	DDB_G0284757	DDB_G0284757	related to the Ovarian Tumour (OTU) gene of Drosophila%3B function is unknown but conserved cysteine and histidine%2C and possibly the aspartate%2C residues suggests that those not yet recognized as peptidases could possess cysteine protease activity
chr4	2442205	2444922	+	DDB_G0284759	psiM	contains a signal peptide%2C a PA14 domain%2C and 4 Dictyostelium (slime mold) repeats%3B enriched in gametes
chr4	2445394	2447839	-	DDB_G0284761	fslA	similar to G-protein-coupled receptors%3B contains 7 putative transmembrane domains and a potential signal sequence
chr4	2448744	2450010	-	DDB_G0284763	DDB_G0284763	NA
chr4	2450678	2451292	-	DDB_G0284765	DDB_G0284765	contains a predicted signal peptide%3B there are two similar genes in D. discoideum
chr4	2452498	2454955	+	DDB_G0284767	DDB_G0284767	weakly related to ABC transporters%3B does not have transmembrane domains
chr4	2456087	2459084	+	DDB_G0284835	aass	bifunctional enzyme: lysine-ketoglutarate reductase (lysine %2B alpha-ketoglutarate %2B NADPH %3D%3E saccharopine)  and saccharopine dehydrogenase (catalyzes the reaction saccharopine %3C%3D%3E L-glutamate %2B 2-aminoadipate 6-semialdehyde %2B NADH %2B H%3Csup%3E%2B%3C%2Fsup%3E)%3B there is a related monofunctional saccharopine reductase %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285267%22%3E%3Ci%3Esdh%3C%2Fi%3E%3C%2Fa%3E
chr4	2459478	2460314	-	DDB_G0284769	vps24	component of the ESCRT-III complex (endosomal sorting complex required for transport)
chr4	2460990	2462924	+	DDB_G0284771	orcF	DNA replication initiation is driven by a conserved six protein complex%2C the origin recognition complex (ORC)%3B has a role in both chromosomal replication and mating type transcriptional silencing
chr4	2467019	2468599	+	DDB_G0284773	DDB_G0284773	contains 10 putative transmembrane domains
chr4	2469559	2471892	+	DDB_G0284775	fut2	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr4	2472579	2473541	+	DDB_G0284777	DDB_G0284777	conserved protein
chr4	2473632	2474831	-	DDB_G0284837	tsnax	ortholog of human TSNAX%3B interacts with translin (TSN)%3B may be involved in RNA metabolism
chr4	2475153	2475233	+	DDB_G0302695	tRNA-Sec-UGA	transfers an selenocysteine residue to a growing polypeptide chain during protein synthesis opposite some TGA codons%3B there are several selenoproteins in Dictyostelium
chr4	2475500	2477179	-	DDB_G0284779	DDB_G0284779	NA
chr4	2477533	2477895	-	DDB_G0284781	DDB_G0284781	NA
chr4	2479165	2480976	+	DDB_G0284783	DDB_G0284783	contains a glutamine-rich region%3B similar to D. purpureum protein
chr4	2481017	2482785	-	DDB_G0284785	nhej1	XLF (also called cernunnos and Nej1 in yeast) interacts with the XRCC4-DNA ligase IV complex to promote DNA non-homologous end-joining
chr4	2483195	2483455	-	DDB_G0284787	DDB_G0284787	NA
chr4	2483989	2486128	+	DDB_G0284789	DDB_G0284789_ps	putative pseudogene%3B similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0276437%22%3EDDB_G0276437%3C%2Fa%3E
chr4	2486260	2488180	-	DDB_G0284791	cpnC	Ca(2%2B)-dependent phospholipid-binding protein%3B contains two C2 domains and a VWFA domain.
chr4	2488840	2489259	-	DDB_G0284793	DDB_G0284793	belongs to the PLAC8 family (placenta-specific gene 8 protein)%2C a family of cysteine-rich proteins with highly divergent%2C low complexity amino terminal regions
chr4	2489743	2491196	-	DDB_G0284795	sir2C	NAD-dependent deacetylase Sirutin 2 family protein%2C that regulates various biological processes by deacetylating histones and other target proteins%3B expressed more highly during vegetative growth 
chr4	2492140	2492451	+	DDB_G0284797	DDB_G0284797_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268836%22%3EDDB_G0268836%3C%2Fa%3E
chr4	2493584	2498100	+	DDB_G0284839	ndrC	member of the AGC kinase group%2C NDR family%3B related to mammalian LATS1 and LATS2 (LArge Tumor Suppressor homolog) kinases 
chr4	2498543	2499047	-	DDB_G0284799	ndufa8	accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)%2C that is believed to be not involved in catalysis
chr4	2499782	2500479	+	DDB_G0284801	DDB_G0284801	NA
chr4	2500893	2501669	-	DDB_G0284805	DDB_G0284805	NA
chr4	2501891	2505360	-	DDB_G0284807	DDB_G0284807	potential extracellular protein that contains a putative signal peptide and one C-terminal transmembrane domain 
chr4	2506040	2506788	-	DDB_G0284809	isca2	conserved protein involved in the assembly of mitochondrial iron-sulfur proteins
chr4	2507767	2508648	+	DDB_G0284811	DDB_G0284811	NA
chr4	2508788	2509215	-	DDB_G0284813	DDB_G0284813	NA
chr4	2510140	2513041	+	DDB_G0284841	DDB_G0284841	NA
chr4	2515068	2515796	+	DDB_G0284843	DDB_G0284843	contains one putative transmembrane domain
chr4	2517388	2518403	+	DDB_G0284815	DDB_G0284815	NA
chr4	2518687	2520706	-	DDB_G0284817	DDB_G0284817	NA
chr4	2520967	2522046	-	DDB_G0284819	DDB_G0284819	NA
chr4	2523362	2524794	+	DDB_G0284821	DDB_G0284821	NA
chr4	2525345	2525738	+	DDB_G0284823	DDB_G0284823	contains one putative transmembrane domain
chr4	2526025	2531286	-	DDB_G0284825	DDB_G0284825	weakly similar to H. sapiens GARNL1%2C a RanGAP
chr4	2532768	2545422	+	DDB_G0284853	DDB_G0284853	large protein that has similarity to mammalian MYC binding protein 2 (MYCBP2)%2C a putative E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.
chr4	2546123	2547106	+	DDB_G0284855	DDB_G0284855	NA
chr4	2547724	2548458	+	DDB_G0284857	cdipt	similar to human CDIPT and S. cerevisiae PIS1 (phosphatidylinositol synthase)%3B catalyzes the reaction CDP-diacylglycerol %2B myo-inositol %3D CMP %2B phosphatidyl-1D-myo-inositol%3B contains 4 putative transmembrane domains
chr4	2549067	2550923	+	DDB_G0284859	samkB	putative protein kinase containing a SAM (sterile alpha motif) homology domain%2C a putative protein interaction module
chr4	2551418	2551697	+	DDB_G0284851	samkB_ps2	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0284859%22%3E%3Ci%3EsamkB%3C%2Fi%3E%3C%2Fa%3E
chr4	2552011	2555903	+	DDB_G0284845	gxcC	plays a role in the regulation of development%3B contains N-terminal armadillo repeats%2C a RhoGEF domain%2C and a C-terminal pleckstrin homology (PH) domain
chr4	2556090	2557087	-	DDB_G0284847	DDB_G0284847	homolog of human SDF2 (stromal cell-derived factor 2)%3B contains 3 MIR domains
chr4	2557758	2561551	+	DDB_G0284849	DDB_G0284849	NA
chr4	2562666	2563088	-	DDB_G0284873	DDB_G0284873_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr4	2563537	2563610	+	DDB_G0295173	tRNA-Phe-GAA-11	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr4	2563672	2564007	+	DDB_G0284875	DDB_G0284875	NA
chr4	2566569	2566856	-	DDB_G0285037	DDB_G0285037	NA
chr4	2568202	2571159	-	DDB_G0285093	DDB_G0285093	NA
chr4	2571519	2572240	-	DDB_G0284865	ubcB	high similarity to E2%2Fubiquitin-conjugating enzymes from yeast%2C metazoans%2C and plants%3B ubiquitin-conjugating enzymes (EC: 6.3.2.19) (UBC or E2 enzymes) catalyze the covalent attachment of ubiquitin to target proteins
chr4	2573154	2577699	-	DDB_G0285045	DDB_G0285045	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr4	2578442	2579226	-	DDB_G0284879	commd2	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr4	2579815	2584663	-	DDB_G0284867	abcC8	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr4	2585806	2586592	+	DDB_G0284881	DDB_G0284881	NA
chr4	2586982	2588331	+	DDB_G0284883	oxaA	similar to OXA1%2C a conserved inner mitochondrial membrane protein that is required for the activity and assembly of cytochrome oxidase and for the insertion of integral membrane proteins into the mitochondrial inner membrane%3B there is a second putative oxidase assembly protein in %3Ci%3ED. discoideum%3Ci%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281171%22%3E%3Ci%3EoxaB%3C%2Fi%3E%3C%2Fa%3E
chr4	2588526	2590107	-	DDB_G0284885	DDB_G0284885	NA
chr4	2593257	2594635	-	DDB_G0285047	DDB_G0285047	NA
chr4	2595117	2596316	-	DDB_G0285049	DDB_G0285049	NA
chr4	2597422	2598751	+	DDB_G0285051	rab32D	weakly similar to rab32 and rab38
chr4	2599094	2600545	-	DDB_G0284887	DDB_G0284887	NA
chr4	2600817	2602140	-	DDB_G0284889	DDB_G0284889	NA
chr4	2602996	2604032	+	DDB_G0284891	rpb7	component of the RNA polymerase II complex%3B ortholog of S. cerevisiae RPB7
chr4	2604439	2605819	-	DDB_G0284893	DDB_G0284893	NA
chr4	2608632	2610914	+	DDB_G0284895	DDB_G0284895	contains an N-terminal SCP domain that occurs in prokaryotic and eukaryotic proteins proposed to be Ca%2B%2B chelating serine proteases%3B also contains two C-terminal WSC domains which are putative carbohydrate binding domains
chr4	2611033	2613269	-	DDB_G0284897	abkD	atypical protein serine%2Fthreonine kinase%2C contains ABC1 kinase (protein kinase-like) domain%3B yeast ABC1 essential for the electron transfer in the BC(1) complex%3B E.coli homolog required for ubiquinone biosynthesis
chr4	2613921	2617056	+	DDB_G0284899	DDB_G0284899	NA
chr4	2617131	2618104	-	DDB_G0284901	DDB_G0284901	similar to human ISOC2 (isochorismatase domain-containing protein 2%2C mitochondrial)%3B contains a predicted peroxisomal targeting signal
chr4	2618768	2619789	-	DDB_G0285053	alrB	member of aldo-keto reductase family%2C which reduces C%3DO to C-OH in aldehydes and ketones
chr4	2620294	2621189	-	DDB_G0285041	DDB_G0285041	similar to human ISOC2 (isochorismatase domain-containing protein 2%2C mitochondrial)%3B contains a predicted peroxisomal targeting signal
chr4	2621558	2624319	-	DDB_G0284903	culC	very similar to mammalian cullin 3 (CUL3)%3B acts as scaffold for ubiquitin ligases (E3)%3B involved in ubiquitin-mediated protein degradation
chr4	2625777	2626566	-	DDB_G0284905	ap4s1	similar to clathrin coat assembly protein AP17
chr4	2626851	2627138	-	DDB_G0284907	DDB_G0284907	expressed in pstO cells and upper cup during culmination
chr4	2628238	2629380	+	DDB_G0284909	DDB_G0284909	NA
chr4	2629450	2630669	-	DDB_G0284869	memo1	ortholog of the H. sapiens MEMO1%2C a mediator of ErbB2-driven cell motility
chr4	2631200	2631555	-	DDB_G0284911	timm10	conserved component of the mitochondrial intermembrane space%2C forms a complex with Timm9%2C which mediates insertion of hydrophobic proteins at the inner membrane.
chr4	2631798	2637863	-	DDB_G0285055	DDB_G0285055	NA
chr4	2638616	2643148	+	DDB_G0284913	DDB_G0284913	NA
chr4	2643291	2644175	-	DDB_G0284915	DDB_G0284915	ortholog of the mammalian MMRP19 (monocyte macrophage 19) protein
chr4	2644494	2646026	-	DDB_G0284917	DDB_G0284917	NA
chr4	2646442	2647519	-	DDB_G0284919	DDB_G0284919	similar to human DHRSX (dehydrogenase%2Freductase SDR family member on chromosome X) and retinol dehydrogenase
chr4	2648206	2649720	+	DDB_G0284921	DDB_G0284921	NA
chr4	2649920	2651674	-	DDB_G0284923	cyp554A1	NA
chr4	2652917	2653325	-	DDB_G0284927	DDB_G0284927	this is one of four almost identical genes on C4 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284931%22%3E%3Ci%3EDDB_G0284931%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285043%22%3E%3Ci%3EDDB_G0285043%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284925%22%3E%3Ci%3EDDB_G0284925%3C%2Fi%3E%3C%2Fa%3E)%2C and there is an additional very similar gene (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0271770%22%3E%3Ci%3EDDB_G0271770%3C%2Fi%3E%3C%2Fa%3E) on C2
chr4	2654790	2655186	-	DDB_G0284925	DDB_G0284925	this is one of four almost identical genes on C4 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284931%22%3E%3Ci%3EDDB_G0284931%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284927%22%3E%3Ci%3EDDB_G0284927%3C%2Fi%3E%3C%2Fa%3E) on C2
chr4	2656766	2657147	+	DDB_G0285043	DDB_G0285043	this is one of four almost identical genes on C4 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284931%22%3E%3Ci%3EDDB_G0284931%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284927%22%3E%3Ci%3EDDB_G0284927%3C%2Fi%3E%3C%2Fa%3E%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284925%22%3E%3Ci%3EDDB_G0284925%3C%2Fi%3E%3C%2Fa%3E)%2C and there is an additional very similar gene (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0271770%22%3E%3Ci%3EDDB_G0271770%3C%2Fi%3E%3C%2Fa%3E) on C2
chr4	2657638	2657886	+	DDB_G0284929	DDB_G0284929	NA
chr4	2659079	2659474	+	DDB_G0284931	DDB_G0284931	this is one of four almost identical genes on C4 (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284927%22%3E%3Ci%3EDDB_G0284927%3C%2Fi%3E%3C%2Fa%3E)%2C and there is an additional very similar gene (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0271770%22%3E%3Ci%3EDDB_G0271770%3C%2Fi%3E%3C%2Fa%3E) on C2
chr4	2659670	2663221	-	DDB_G0284933	DDB_G0284933	NA
chr4	2664011	2665078	+	DDB_G0284935	DDB_G0284935	NA
chr4	2665360	2666735	+	DDB_G0284937	DDB_G0284937	belongs to the integral membrane proteins that are related to Drosophila rhomboid protein that promotes the cleavage of a membrane-anchored TGF-alpha-like growth factor
chr4	2666993	2667577	-	DDB_G0285057	DDB_G0285057	NA
chr4	2667885	2668401	+	DDB_G0284939	DDB_G0284939	NA
chr4	2668956	2669455	+	DDB_G0284941	DDB_G0284941	similar to mammalian thioredoxin 2
chr4	2669585	2671865	-	DDB_G0284943	DDB_G0284943	NA
chr4	2672551	2675180	-	DDB_G0284945	fsjC	RrmJ%2FFtsJ ribosomal RNA methyltransferase family member%3B well conserved heat shock proteins present in prokaryotes%2C archaea%2C and eukaryotes%3B this is the ortholog of H. sapiens FTSJ3%3B involved in rRNA processing and 60S ribosomal subunit maturation (yeast)
chr4	2675998	2677138	+	DDB_G0284947	ucr	conserved ubiquinol-cytochrome c oxidoreductase subunit%2C a component of the mitochondrial inner membrane electron transport chain
chr4	2677540	2677816	-	DDB_G0284949	DDB_G0284949	NA
chr4	2678890	2680008	+	DDB_G0284951	vamp7A	member of the SNARE family (Soluble NSF Attachment Protein REceptor)%3B localizes to endosome and interacts with syn7A
chr4	2680203	2684167	-	DDB_G0284953	oplah	catalyzes the reaction ATP %2B 5-oxo-L-proline %2B 2 H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E ADP %2B phosphate %2B L-glutamate
chr4	2684549	2689245	-	DDB_G0284955	DDB_G0284955	NA
chr4	2691906	2693567	+	DDB_G0284863	limB	NA
chr4	2694222	2696687	+	DDB_G0284957	DDB_G0284957	NA
chr4	2696768	2698214	-	DDB_G0285059	DDB_G0285059	NA
chr4	2698477	2699183	+	DDB_G0284959	DDB_G0284959	ortholog of the conserved OPA3%3B in H. sapiens%2C defects in OPA3 cause type III 3-methylglutaconic aciduria (MGA type III)%2C also known as optic atrophy plus syndrome
chr4	2699345	2699985	-	DDB_G0284961	DDB_G0284961	similar to human ZNHIT1
chr4	2700406	2702424	+	DDB_G0284963	DDB_G0284963	similar to bacterial and eukaryotic acyl-CoA synthetases
chr4	2702978	2703894	-	DDB_G0284965	DDB_G0284965	NA
chr4	2704245	2706791	-	DDB_G0284967	DDB_G0284967	NA
chr4	2707152	2718912	-	DDB_G0285063	DDB_G0285063	similar to the H. sapiens HUWE1%2C an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.
chr4	2719814	2721577	+	DDB_G0284969	DDB_G0284969	NA
chr4	2722034	2723623	-	DDB_G0285065	DDB_G0285065	NA
chr4	2726690	2727950	+	DDB_G0284971	DDB_G0284971	contains three putative transmembrane domains
chr4	2728155	2731002	-	DDB_G0285067	exoc1	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr4	2731379	2735364	+	DDB_G0284973	DDB_G0284973	NA
chr4	2735507	2737979	-	DDB_G0284975	tpsB	CAZy family GT20%3B contains an N-terminal glycosyltransferase domain and a C-terminal trehalose-phosphatase domain
chr4	2738670	2742984	-	DDB_G0284977	DDB_G0284977	NA
chr4	2743512	2744492	-	DDB_G0284979	DDB_G0284979	conserved in amoeba
chr4	2745658	2747307	+	DDB_G0284981	DDB_G0284981	NA
chr4	2748189	2749460	+	DDB_G0285069	btg	interacts with RblA to control cell fate commitment during development%3B homolog of mammalian BTG2
chr4	2750152	2751628	+	DDB_G0285071	echs1	conserved protein%3B catalyzes the reaction (3S)-3-hydroxyacyl-CoA %3C%3D%3E trans-2(or 3)-enoyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO
chr4	2752867	2755644	+	DDB_G0284983	colD	NA
chr4	2756032	2757408	-	DDB_G0284985	rab1D	similar to rab1B
chr4	2757052	2757145	+	DDB_G0295591	r55	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	2758636	2761135	+	DDB_G0285073	DDB_G0285073	putative VPS9 ortholog%2C a guanine nucleotide exchange factor involved in vesicle-mediated  vacuolar protein transport
chr4	2762877	2764154	-	DDB_G0284987	repG	similar to H. sapiens xeroderma pigmentosum group G (XPG)%2C M. musculus ERCC5 and S. pombe RAD2%3B cleaves 5%27 overhang flap structure generated when DNA polymerase encounters the 5%27end of a downstream Okazaki fragment 
chr4	2766075	2766554	+	DDB_G0284861	eif5a	NA
chr4	2767691	2767968	+	DDB_G0294413	srpA	signal recognition particle (SRP) RNA%3B forms the SRP complex with the SRP 72%2C 68%2C 54%2C 19%2C 14%2C and 9 proteins
chr4	2772764	2774260	-	DDB_G0284871	DDB_G0284871	HMG-I and HMG-Y proteins bind specifically to the minor groove of AT-rich sequences via an 11-residue domain known as an AT-hook
chr4	2775844	2776212	-	DDB_G0295593	pRNA	RNA component of ribonuclease P (RNase P) involved in generating mature 5%27 ends of tRNA
chr4	2776760	2778139	+	DDB_G0285075	DDB_G0285075_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0285087%22%3EDDB_G0285087%3C%2Fa%3E
chr4	2778336	2781617	+	DDB_G0284991	DDB_G0284991	NA
chr4	2782082	2782210	-	DDB_G0284993	DDB_G0284993	NA
chr4	2782622	2783781	+	DDB_G0284995	DDB_G0284995	NA
chr4	2784039	2785261	-	DDB_G0284997	DDB_G0284997	NA
chr4	2786060	2786976	-	DDB_G0284999	DDB_G0284999	conserved hypothetical 277 aa Dictyostelium protein
chr4	2788466	2790220	+	DDB_G0285001	DDB_G0285001	NA
chr4	2790283	2791622	-	DDB_G0285003	aifC	similar to H. sapiens AIFM2%2C a caspase-independent mitochondrial effector of apoptotic cell death
chr4	2792181	2792238	-	DDB_G0295595	r56	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	2793529	2793577	+	DDB_G0295597	r57	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr4	2793917	2793971	+	DDB_G0295599	r32	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	2794340	2795503	-	DDB_G0285005	aifB	similar to H. sapiens AIFM2%2C a caspase-independent mitochondrial effector of apoptotic cell death
chr4	2796145	2796786	-	DDB_G0285007	prafB	belongs to a conserved family of multi-pass transmembrane proteins%3B contains 4 predicted transmembrane domains
chr4	2797226	2798837	+	DDB_G0304561	DDB_G0304561	similar to solute carrier family 35 member E4 (SLC35E4) proteins%3B contains 10 predicted transmembrane domains
chr4	2799520	2801698	+	DDB_G0285077	u2af1	small subunit of the U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) which is a splicing factor that forms a heterodimer with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0286395%22%3E%3Ci%3Eu2af2%3C%2Fi%3E%3C%2Fa%3E
chr4	2802048	2802865	+	DDB_G0285079	DDB_G0285079	NA
chr4	2803238	2804472	-	DDB_G0285009	hemD	catalyzes the reaction hydroxymethylbilane %3C%3D%3E uroporphyrinogen III %2B H%3Csub%3E2%3C%2Fsub%3EO in heme biosynthesis
chr4	2804851	2805754	-	DDB_G0285095	DDB_G0285095	NA
chr4	2808780	2813839	+	DDB_G0285081	DDB_G0285081	NA
chr4	2814046	2815374	-	DDB_G0285011	DDB_G0285011	similar to the fungi mitochondrial transferase caf17%2C a mitochondrial matrix protein involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins
chr4	2815942	2819113	+	DDB_G0285083	DDB_G0285083	NA
chr4	2820125	2820517	+	DDB_G0285085	DDB_G0285085_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0276527%22%3EDDB_G0276527%3C%2Fa%3E
chr4	2820652	2821932	+	DDB_G0285013	DDB_G0285013	NA
chr4	2822210	2823458	-	DDB_G0285015	DDB_G0285015_ps	putative pseudogene%3B similar to a Dictyostelium family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0285019%22%3E DDB_G0285019%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0292578%22%3EDDB_G0292578%3C%2Fa%3E
chr4	2823631	2827116	-	DDB_G0285019	DDB_G0285019	NA
chr4	2827341	2829545	-	DDB_G0285087	DDB_G0285087	NA
chr4	2830332	2830877	-	DDB_G0285021	DDB_G0285021	belongs to the complex I LYR family%3B similar to human NDUFB9 (NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9)
chr4	2831142	2832170	-	DDB_G0285023	alrF	member of aldo-keto reductase family%2C which reduces C%3DO to C-OH in aldehydes and ketones
chr4	2832495	2833482	-	DDB_G0285025	alrE	member of aldo-keto reductase family%2C which reduces C%3DO to C-OH in aldehydes and ketones
chr4	2833891	2834847	-	DDB_G0285027	alrD	member of aldo-keto reductase family%2C which reduces C%3DO to C-OH in aldehydes and ketones
chr4	2834988	2836314	-	DDB_G0285029	sfxn	very similar to mammalian sideroflexins%2C especially SFXN 5 and SFXN3%2C and to %3Ci%3ES. cerevisieae%3C%2Fi%3E FSF1%3B contains five putative transmembrane domains
chr4	2836987	2839374	-	DDB_G0285031	DDB_G0285031	NA
chr4	2839925	2840710	+	DDB_G0285033	DDB_G0285033	belongs to the short-chain dehydrogenase%2Freductase family
chr4	2841024	2841095	+	DDB_G0295175	tRNA-Asp-GUC-12	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr4	2841164	2841490	+	DDB_G0285035	DDB_G0285035_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr4	2841636	2844830	+	DDB_G0285089	DDB_G0285089_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr4	2845703	2845774	-	DDB_G0295225	tRNA-Asp-GUC-18	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr4	2847730	2847945	-	DDB_G0285091	DDB_G0285091_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr4	2848300	2849418	+	DDB_G0285097	DDB_G0285097_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr4	2851187	2852364	+	DDB_G0285103	DDB_G0285103	NA
chr4	2852779	2854360	+	DDB_G0285105	psmD13	NA
chr4	2855138	2855823	+	DDB_G0285107	DDB_G0285107	NA
chr4	2856191	2862064	+	DDB_G0285101	kif4	belongs to the CENP-E subfamily%2C predicted to play a role in mitosis%3B has a putative nuclear localization signal C-terminal to its motor domain
chr4	2862240	2863214	-	DDB_G0285109	DDB_G0285109	NA
chr4	2863727	2864850	-	DDB_G0285111	snpA	NA
chr4	2865898	2867728	+	DDB_G0285113	DDB_G0285113	similar to human MUDENG (MHD domain-containing death-inducing protein) which induces cell death in cytotoxic T-cells%3B contains one MHD domain (mu homology domain)
chr4	2868305	2869036	+	DDB_G0285151	DDB_G0285151	NA
chr4	2869433	2870475	+	DDB_G0285153	DDB_G0285153	NA
chr4	2872325	2872963	+	DDB_G0285115	DDB_G0285115	NA
chr4	2873116	2876085	-	DDB_G0285117	rad54b	similar to RAD54b DNA repair protein%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr4	2877924	2879489	+	DDB_G0285119	DDB_G0285119	NA
chr4	2880074	2881142	+	DDB_G0285099	psmE3	PA28 activator subunit of the 20S proteasome%3B animals contain 3 different subunits: alpha%2C beta%2C and gamma%3B the alpha and beta subunits are only present in animals possessing an adaptive immune system%3B %3Ci%3EDictyostelium%3C%2Fi%3E has the gamma ortholog only%3B PsmE3 is localized to the nucleus%2C similar to the gamma class of REG proteasome activator in metazoans
chr4	2881701	2881997	+	DDB_G0285121	DDB_G0285121	NA
chr4	2882150	2884484	+	DDB_G0285123	DDB_G0285123	NA
chr4	2884598	2886443	-	DDB_G0285125	DDB_G0285125	NA
chr4	2886739	2887924	-	DDB_G0285127	DDB_G0285127	NA
chr4	2888446	2890076	-	DDB_G0285149	DDB_G0285149	similar to mammalian TNF receptor-associated factors 5 and 6 (TRAF5%2C TRAF6)
chr4	2891853	2894373	-	DDB_G0285155	DDB_G0285155	NA
chr4	2894961	2895998	+	DDB_G0285129	DDB_G0285129	NA
chr4	2896240	2897333	-	DDB_G0285131	derl2	component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins%3B contains 5 putative transmembrane domains
chr4	2898787	2899379	+	DDB_G0285157	DDB_G0285157	NA
chr4	2899851	2902292	+	DDB_G0285159	stt3	CAZy family GT66%3B subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of S. cerevisiae OST1%3B contains 13 transmembrane domains
chr4	2902514	2902867	-	DDB_G0285133	mocs2s	NA
chr4	2903243	2903902	-	DDB_G0285135	DDB_G0285135	NA
chr4	2905081	2907503	+	DDB_G0285137	mocs1	NA
chr4	2908294	2910216	+	DDB_G0285139	gtaL	has 18 amino acids between the two CX2C motifs 
chr4	2910487	2911895	-	DDB_G0285141	osbJ	NA
chr4	2913006	2914361	-	DDB_G0285143	DDB_G0285143	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0295693%22%3E%3Ci%3EDDB_G0295693%3C%2Fi%3E%3C%2Fa%3E
chr4	2915991	2917295	+	DDB_G0285145	DDB_G0285145	NA
chr4	2919389	2920363	+	DDB_G0285167	DDB_G0285167	NA
chr4	2921996	2926921	+	DDB_G0285205	snf2a	SNF2 family protein%2C similar to human SMARCA4%3B putative regulator of chromatin
chr4	2927541	2928266	+	DDB_G0285207	DDB_G0285207_ps	putative pseudogene%3B highly similar to %3Ca href%3D%22%2Fgene%2FDDB_G0292844%22%3EDDB_G0292844%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0292962%22%3EDDB_G0292962%3C%2Fa%3E
chr4	2928529	2931348	-	DDB_G0285169	DDB_G0285169	NA
chr4	2932277	2933000	+	DDB_G0285171	DDB_G0285171_ps	putative pseudogene%3B highly similar to %3Ca href%3D%22%2Fgene%2FDDB_G0292844%22%3EDDB_G0292844%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0292962%22%3EDDB_G0292962%3C%2Fa%3E
chr4	2933402	2936143	-	DDB_G0285173	DDB_G0285173	NA
chr4	2937306	2938857	+	DDB_G0285175	vmp1	conserved protein required for biogenesis of the contractile vacuole in response to osmotic stress%3B contains 8 predicted transmembrane domains
chr4	2939040	2940434	-	DDB_G0285177	DDB_G0285177	NA
chr4	2941521	2941979	+	DDB_G0285203	DDB_G0285203	NA
chr4	2942482	2946715	+	DDB_G0285165	abcC9	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr4	2946825	2949854	-	DDB_G0285163	gacT	weakly similar to similar to RalA binding protein 1%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FGacT%22%3Ecommunity annotation%3C%2Fa%3E
chr4	2951533	2952479	+	DDB_G0285209	DDB_G0285209	NA
chr4	2952647	2953733	+	DDB_G0285197	gpn3	conserved protein
chr4	2954586	2955503	+	DDB_G0285179	DDB_G0285179	NA
chr4	2955670	2956181	-	DDB_G0285181	DDB_G0285181	contains a predicted peroxisomal targeting signal
chr4	2957139	2960755	+	DDB_G0285183	DDB_G0285183	NA
chr4	2960975	2962133	+	DDB_G0285185	DDB_G0285185	NA
chr4	2962656	2962943	-	DDB_G0285187	DDB_G0285187	NA
chr4	2964201	2964662	-	DDB_G0285189	DDB_G0285189	NA
chr4	2965339	2967249	-	DDB_G0285191	DDB_G0285191	contains a protein tyrosine phosphatase catalytic region and two transmembrane domains
chr4	2968644	2971150	-	DDB_G0285201	DDB_G0285201	NA
chr4	2972049	2972780	+	DDB_G0285193	hprT	catalyzes the reaction PRPP %2B hypoxanthine %3D pyrophosphate %2B IMP in the salvage pathways of purine nucleosides%3B %3Cbr%2F%3E overexpressed in dstB (STATb) null mutants
chr4	2973018	2975319	-	DDB_G0285161	dagA	pleckstrin homology (PH) domain protein required for receptor-mediated activation of adenylyl cyclase
chr4	2979542	2980601	+	DDB_G0294515	dutA	untranslatable RNA%3B overexpression of dutA segments suppresses the culmination mutant phenotype of STATa (dstA)%2C revealing an inhibitory role of dutA in culmination%3B accordingly%2C dutA expression ceases with the onset of culmination%3B dutA segment overexpression is also correlated with increased tyrosine phosphorylation of STATa
chr4	2981196	2983477	-	DDB_G0285233	DDB_G0285233	ortholog of mammalian CWF19l1 and S. pombe mug161
chr4	2984261	2986444	+	DDB_G0285213	dhx15	conserved pre-mRNA processing factor involved in the disassembly of spliceosomes after the release of mature mRNA
chr4	2987082	2988608	-	DDB_G0285215	DDB_G0285215	domain similarity to domains in bacterial hypothetical proteins
chr4	2989226	2989556	-	DDB_G0285217	tgrE_ps	putative pseudogene%3B immunoglobulin E-set family gene
chr4	2989642	2990096	+	DDB_G0285235	DDB_G0285235	NA
chr4	2990906	2991704	+	DDB_G0285237	DDB_G0285237	NA
chr4	2992421	2993347	+	DDB_G0285219	DDB_G0285219	contains a predicted signal peptide
chr4	2993554	2995278	-	DDB_G0285211	fadA	contains the histidine box motif characteristic of fatty acid desaturases
chr4	2996613	2997218	-	DDB_G0285221	med31	ortholog of the mediator of RNA polymerase II transcription subunit 31%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr4	2997614	2998150	-	DDB_G0285239	ndufs7	accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)
chr4	2998910	3005650	+	DDB_G0285243	DDB_G0285243	has partial similarity to the S. cerevisiae SEN1%2C a putative helicase required for RNA polymerase II transcription termination and processing of RNAs
chr4	3006660	3009599	-	DDB_G0285245	DDB_G0285245	NA
chr4	3010019	3013263	+	DDB_G0285223	anapc4	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr4	3013770	3015638	+	DDB_G0285225	DDB_G0285225	NA
chr4	3016456	3017436	-	DDB_G0285249	DDB_G0285249	NA
chr4	3018261	3018983	-	DDB_G0285229	DDB_G0285229	NA
chr4	3019660	3020199	-	DDB_G0285301	DDB_G0285301	NA
chr4	3020871	3022010	+	DDB_G0285255	DDB_G0285255	NA
chr4	3022479	3024536	+	DDB_G0285257	fpgt	ortholog of the fucose-1-phosphate guanylyltransferase%2C conserved among higher eukaryotes and in %3Ci%3EDictyostelium%3C%2Fi%3E%3B catalyzes the reaction: GTP %2B beta-L-fucose 1-phosphate %3D diphosphate %2B GDP-L-fucose
chr4	3024689	3026832	-	DDB_G0285259	DDB_G0285259	NA
chr4	3027528	3028793	+	DDB_G0285261	DDB_G0285261	NA
chr4	3029253	3029324	-	DDB_G0295223	tRNA-Asp-GUC-17	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr4	3029506	3032100	-	DDB_G0285263	spyA	CAZy family GT41%3B contains 7 TPRs (Tetratrico Peptide Repeats)
chr4	3032493	3032998	-	DDB_G0285265	DDB_G0285265	contains one EF hand%3B similar to calmodulin
chr4	3034209	3035835	+	DDB_G0285267	sdh	catalyzes the reaction saccharopine %2B NAD%3Csup%3E%2B%3C%2Fsup%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E L-glutamate %2B 2-aminoadipate 6-semialdehyde %2B NADH %2B H%3Csup%3E%2B%3C%2Fsup%3E%3B there is also a bifunctional enzyme (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0284835%22%3E%3Ci%3Eaass%3C%2Fi%3E%3C%2Fa%3E) which additionally has lysine-ketoglutarate reductase activity
chr4	3035959	3036729	-	DDB_G0285251	rsc43	NA
chr4	3037532	3038673	+	DDB_G0285269	DDB_G0285269	similar to H. sapiens CNOT7 and CNOT8 and S. cerevisiae POP2
chr4	3039035	3042432	+	DDB_G0285297	DDB_G0285297	NA
chr4	3042778	3046100	+	DDB_G0285271	DDB_G0285271	NA
chr4	3047069	3047766	+	DDB_G0285273	DDB_G0285273	highly conserved protein containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr4	3047966	3048910	-	DDB_G0285275	DDB_G0285275	NA
chr4	3049805	3050587	+	DDB_G0285277	rpl17	protein component of the large (60S) ribosomal subunit
chr4	3050725	3051108	-	DDB_G0285279	DDB_G0285279	NA
chr4	3051378	3053132	-	DDB_G0285303	gxcR	NA
chr4	3053971	3054847	+	DDB_G0285281	DDB_G0285281	NA
chr4	3055336	3056667	+	DDB_G0285253	scrA	adaptor protein that couples Rho GTPases and the Arp2%2F3 complex to stimulate actin polymerization
chr4	3057091	3057162	-	DDB_G0295221	tRNA-Asp-GUC-16	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr4	3058106	3060463	-	DDB_G0285283	DDB_G0285283	NA
chr4	3060850	3062356	-	DDB_G0285285	DDB_G0285285	NA
chr4	3062767	3063831	-	DDB_G0285287	DDB_G0285287	putative ortholog of Rad51D%2C which is involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks
chr4	3064118	3065099	-	DDB_G0285289	DDB_G0285289	NA
chr4	3065810	3067048	-	DDB_G0285291	DDB_G0285291	NA
chr4	3068070	3068424	+	DDB_G0285293	spt4	ortholog of the human SUPT4H1 and S. cerevisiae SPT4 (suppressor of Ty 4)%2C a transcription-elongation factor that is tightly associated in a complex with SPT5
chr4	3068985	3070104	-	DDB_G0285295	vps28	component of the ESCRT-I complex (endosomal sorting complex required for transport)
chr4	3070354	3071988	-	DDB_G0285299	DDB_G0285299	NA
chr4	3073029	3073100	+	DDB_G0295177	tRNA-Asp-GUC-13	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr4	3073434	3075593	+	DDB_G0285305	DDB_G0285305_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3075949	3077009	+	DDB_G0285307	DDB_G0285307_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr4	3077952	3080801	+	DDB_G0285309	DDB_G0285309	NA
chr4	3080971	3081817	-	DDB_G0285311	gpmA	catalyzes the reaction 3-phosphoglycerate %3C%3D%3E 2-phosphoglycerate
chr4	3082073	3088037	-	DDB_G0285313	cepH	NA
chr4	3088593	3089954	-	DDB_G0285315	DDB_G0285315_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3090138	3090545	-	DDB_G0285317	DDB_G0285317_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3091037	3092989	+	DDB_G0285325	DDB_G0285325_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3094412	3095908	-	DDB_G0285329	DDB_G0285329	C-terminal half very similar to nucleotide binding protein 1%3B belongs to the highly conserved Mrp%2FNBP35 ATP-binding protein family
chr4	3096169	3097483	+	DDB_G0285331	DDB_G0285331	NA
chr4	3097865	3099004	-	DDB_G0285333	DDB_G0285333	NA
chr4	3099238	3101004	-	DDB_G0285335	DDB_G0285335	NA
chr4	3101144	3102259	-	DDB_G0285337	DDB_G0285337	NA
chr4	3103340	3105247	+	DDB_G0285339	mipp1	enzyme that hydrolyzes 2%2C3 bisphosphoglycerate to yield 2-phosphoglycerate
chr4	3105820	3107493	+	DDB_G0285341	DDB_G0285341	NA
chr4	3107718	3108433	-	DDB_G0285389	DDB_G0285389	putative ortholog of H. sapiens UXT (ubiquitously-expressed transcript)%3B related to prefoldin alpha
chr4	3109098	3113348	-	DDB_G0285391	xacC	NA
chr4	3114831	3115617	+	DDB_G0285343	gtf2a2	important but not essential for transcriptional activation%2C functioning as either an antirepressor or a coactivator
chr4	3116252	3116615	-	DDB_G0285345	DDB_G0285345	contains a predicted signal peptide
chr4	3118848	3119438	-	DDB_G0285347	DDB_G0285347	NA
chr4	3120198	3127799	-	DDB_G0285393	ints1	ortholog of integrator complex subunit 1%2C component of a multiprotein mediator of small nuclear RNA processing
chr4	3131349	3134816	+	DDB_G0285321	splB	member of the TKL (tyrosine kinase-like) group%3B activates the transcriptional regulator STATc
chr4	3135215	3142138	-	DDB_G0285349	anapc1	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr4	3142648	3143310	-	DDB_G0285395	snrpD2	NA
chr4	3145643	3146185	+	DDB_G0285319	H1	linker histone H1%2FH5 family protein%3B plays a role in formation of 30 nm chromatin fiber
chr4	3146811	3148175	-	DDB_G0285351	DDB_G0285351	NA
chr4	3149443	3150879	-	DDB_G0285397	DDB_G0285397	NA
chr4	3151723	3152583	+	DDB_G0285399	cyb5r1	catalyzes the reaction NADH %2B 2 ferricytochrome b5 %3D NAD(%2B) %2B H(%2B) %2B 2 ferrocytochrome%3B involved in             desaturation and elongation of fatty acids%2C cholesterol             biosynthesis%2C and drug metabolism 
chr4	3152730	3153630	-	DDB_G0285353	hus1	similar to Hus1%2C a component of a heterotrimeric clamp (the 9-1-1 complex) that recognizes damaged DNA and initiates signal transduction for repair
chr4	3154785	3157637	+	DDB_G0285401	DDB_G0285401	NA
chr4	3157812	3161532	-	DDB_G0285403	DDB_G0285403	NA
chr4	3164414	3165004	+	DDB_G0285355	DDB_G0285355	NA
chr4	3165268	3166362	-	DDB_G0285357	DDB_G0285357	similar to FKBP-type peptidyl-prolyl isomerase%2C which functions as a receptor for immunosuppressants in vertebrates
chr4	3166879	3167823	-	DDB_G0285359	DDB_G0285359	NA
chr4	3169327	3170469	-	DDB_G0285361	DDB_G0285361	similar to human THO complex 4 (THOC4)
chr4	3170836	3171882	-	DDB_G0285363	DDB_G0285363	NA
chr4	3173380	3174146	+	DDB_G0285365	DDB_G0285365	NA
chr4	3174564	3175377	+	DDB_G0285369	DDB_G0285369_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0285365%22%3E DDB_G0285365 %3C%2Fa%3E
chr4	3175505	3178374	-	DDB_G0285405	DDB_G0285405	NA
chr4	3179167	3181707	-	DDB_G0285371	gnl1	similar to the conserved guanine nucleotide-binding protein-like 1 
chr4	3182160	3184727	+	DDB_G0285373	mybL	contains four Myb DNA-binding domains near the C-terminus of the predicted protein
chr4	3184814	3188598	-	DDB_G0285409	DDB_G0285409	NA
chr4	3189133	3193729	+	DDB_G0285411	DDB_G0285411	contains a putative TRAF-type zinc finger
chr4	3194807	3197134	+	DDB_G0285323	atg9	Dictyostelium homolog of yeast atg9%3B involved in phagocytosis%2C growth%2C development%2C and the response to pathogen bacteria%3B contains 6 predicted transmembrane domains
chr4	3197399	3198752	-	DDB_G0285375	atg18	ortholog of the conserved fungi ATG18 and very similar to the mammalian WIPI2 and WIPI1 proteins%3B contains 2 WD-40 repeats
chr4	3199348	3200252	+	DDB_G0285413	DDB_G0285413	NA
chr4	3200903	3204038	+	DDB_G0285415	nup85	similar to the conserved Nup85%2C component of the nuclear pore complex
chr4	3204171	3204931	-	DDB_G0285377	DDB_G0285377	NA
chr4	3205403	3205717	-	DDB_G0285379	DDB_G0285379	NA
chr4	3206066	3209653	-	DDB_G0285381	polD1	required for chromomsomal DNA replication%3B contains a polymerase and a 3%27-%3E5%27 exonuclease domain
chr4	3210654	3210791	-	DDB_G0285383	DDB_G0285383	NA
chr4	3211353	3212490	-	DDB_G0285385	DDB_G0285385	NA
chr4	3213388	3213867	-	DDB_G0295789	DDB_G0295789	shares a short region of similarity with GRP1 (general receptor for phosphoinositides 1)-associated scaffold  protein%3B contains one transmembrane domain
chr4	3214213	3216378	+	DDB_G0285735	DDB_G0285735	NA
chr4	3216790	3223018	-	DDB_G0285435	DDB_G0285435	NA
chr4	3223269	3224237	+	DDB_G0285437	DDB_G0285437	NA
chr4	3224754	3227388	+	DDB_G0285439	DDB_G0285439	NA
chr4	3227919	3228219	+	DDB_G0285441	DDB_G0285441	related to the hssA genes
chr4	3228708	3228993	-	DDB_G0285737	DDB_G0285737	related to hssA genes
chr4	3229422	3229891	+	DDB_G0285443	DDB_G0285443	related to the hssA genes
chr4	3230059	3233762	-	DDB_G0285445	DDB_G0285445	has the same domain composition as %3Ci%3EfbxA%3C%2Fi%3E and %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0280895%22%3E%3Ci%3EDDB_G0280895%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E: contains an N-terminal START (StAR-related lipid-transfer) lipid binding domain%2C a central F-box domain%2C and five C-terminal WD40 repeats
chr4	3236291	3237462	-	DDB_G0285447	DDB_G0285447	conserved protein%3B contains 2 putative transmembrane domains
chr4	3237973	3240213	-	DDB_G0285449	DDB_G0285449	dual specificity phosphatases remove phosphate groups from tyrosine and serine%2Fthreonine residues 
chr4	3240792	3244287	+	DDB_G0285451	leuS	catalyzes the reaction ATP %2B L-leucine %2B tRNALeu %3D AMP %2B diphosphate %2B L-leucyl-tRNALeu
chr4	3245052	3246717	+	DDB_G0285453	racP	NA
chr4	3246902	3248617	-	DDB_G0285431	dia1	specifically expressed during the transition from growth to development%3B serine-rich protein%2C possibly anchored to the plasma membrane%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with forF often called Ddia1 encoding a diaphanous formin
chr4	3249271	3249957	+	DDB_G0285455	impA	highly similar to FKBP-type peptidyl-prolyl isomerase%2C which functions as a receptor for immunosuppressants in vertebrates%3B the impA promoter is shared with and inversely regulated with dia1 during the growth-development transition
chr4	3250615	3250916	+	DDB_G0285457	impA_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0285455%22%3E%3Ci%3EimpA%3C%2Fi%3E%3C%2Fa%3E
chr4	3251052	3252050	-	DDB_G0285739	DDB_G0285739	NA
chr4	3253005	3253818	+	DDB_G0285433	phlp2	NA
chr4	3255042	3256116	+	DDB_G0285741	prdx5	ortholog of peroxiredoxin 5
chr4	3256332	3257228	+	DDB_G0285459	DDB_G0285459	dual specificity phosphatases remove phosphate groups from tyrosine and serine%2Fthreonine residues 
chr4	3257355	3258935	-	DDB_G0285461	pigK	NA
chr4	3259648	3261800	-	DDB_G0285463	DDB_G0285463	member of the TKL (tyrosine kinase-like) group and the CZAK (C-terminal domain of ZakA) family%3B contains 7 putative transmembrane domains
chr4	3263032	3265230	-	DDB_G0285465	nog1	very similar to NOG1%2FGTPBP4 GTPases%2C which in %3Ci%3ES. cerevisiae%3C%2Fi%3E associates with free 60S ribosomal subunits in the nucleolus and is involved in their biogenesis
chr4	3266519	3268010	+	DDB_G0285467	DDB_G0285467	very similar to bacterial N-ethylammeline chlorohydrolases
chr4	3270785	3271141	+	DDB_G0285469	DDB_G0285469	NA
chr4	3271863	3274196	-	DDB_G0285743	DDB_G0285743	NA
chr4	3274352	3274782	+	DDB_G0285471	DDB_G0285471	belongs to the DUF836 family%3B similar to S. cerevisiae glutaredoxin-like protein YDR286C
chr4	3274945	3275601	-	DDB_G0285473	DDB_G0285473	NA
chr4	3277201	3277834	-	DDB_G0285475	cbpD3_ps	putative pseudogene%3B very similar to %3Ci%3EDicyostelium%3C%2Fi%3E cbpD1 and cbpD2 but missing their conserved N-terminal 15 amino acids
chr4	3279052	3279333	-	DDB_G0285477	DDB_G0285477	NA
chr4	3279817	3282948	-	DDB_G0285745	DDB_G0285745_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271042%22%3EDDB_G0271042%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0285585%22%3EDDB_G0285585%3C%2Fa%3E
chr4	3284415	3289240	+	DDB_G0348834	DDB_G0348834	NA
chr4	3289563	3294374	+	DDB_G0348835	DDB_G0348835	NA
chr4	3294537	3296140	-	DDB_G0285481	DDB_G0285481	NA
chr4	3297334	3302185	+	DDB_G0285483	DDB_G0285483	NA
chr4	3302460	3304636	-	DDB_G0285485	DDB_G0285485	protein family conserved in protozoans%2C fungi%2C and invertebrate animals
chr4	3305672	3307876	-	DDB_G0285487	DDB_G0285487	protein family conserved in protozoans%2C fungi%2C and invertebrate animals
chr4	3308405	3308952	+	DDB_G0285489	DDB_G0285489	similar to human TRMT112%2C S. cerevisiae TRM112 (multifunctional methyltransferase subunit TRM112) 
chr4	3308999	3309805	-	DDB_G0285491	DDB_G0285491	NA
chr4	3310297	3311653	+	DDB_G0285493	DDB_G0285493	NA
chr4	3311819	3313306	-	DDB_G0285495	DDB_G0285495	NA
chr4	3313914	3314438	+	DDB_G0285497	DDB_G0285497	NA
chr4	3314745	3319892	+	DDB_G0285499	DDB_G0285499	NA
chr4	3320060	3320130	-	DDB_G0295219	tRNA-Gly-GCC-11	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr4	3320206	3320278	-	DDB_G0295217	tRNA-Asn-GUU-13	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3320640	3321608	-	DDB_G0285501	DDB_G0285501	NA
chr4	3322100	3323816	+	DDB_G0285503	dynB	ortholog of dynactin 2
chr4	3324153	3325825	-	DDB_G0285505	ino1	catalyzes the reaction D-glucose 6-phosphate %3C%3D%3E 1D-myo-inositol 3-phosphate%3B enzyme activity is reduced by valproate
chr4	3327387	3328942	-	DDB_G0285507	clp1	ortholog of the conserved CLP1 protein%3B S. cerevisiae CLP1 is involved in both the endonucleolytic cleavage and polyadenylation steps of mRNA 3%27-end maturation%3B   Mammalian CLP1 is a subunit of cleavage complex IIA%2C which is required for cleavage%2C but not for polyadenylation of pre-mRNA
chr4	3329709	3330998	+	DDB_G0285509	bcaA	catalyzes the reaction 2-keto-3-methyl-valerate %2B L-glutamate %3D L-iso-leucine %2B %26alpha%3B-ketoglutarate
chr4	3331170	3332852	-	DDB_G0285511	DDB_G0285511	contains 12 putative transmembrane domains
chr4	3334165	3335058	-	DDB_G0285513	asf1	conserved nucleosome assembly factor and histone chaperone protein
chr4	3335964	3337568	+	DDB_G0285515	ppan	ortholog of the Drosophila Peter Pan gene%2C that when mutated%2C results in larvae that do not grow and show minimal DNA replication
chr4	3338968	3339690	+	DDB_G0285517	DDB_G0285517	similar to D. purpureum protein
chr4	3339980	3340927	-	DDB_G0285519	DDB_G0285519	NA
chr4	3341295	3342382	+	DDB_G0285521	isy1	ortholog of human and yeast ISY1%2C which plays a role in mRNA splicing
chr4	3342493	3344145	-	DDB_G0285523	pex12	ortholog of peroxin 12%2C a RING-finger peroxisomal membrane peroxin that plays an essential role in peroxisome biogenesis and peroxisomal matrix protein import%2C forms translocation subcomplex with peroxin 2 and peroxin 10%3B mutations in human homolog cause a variety of peroxisomal disorders
chr4	3344366	3344989	-	DDB_G0285525	DDB_G0285525	phosphorylates dephospho-CoA to CoA%3B in other organisms%2C this activity is part of a bifunctional enzyme that also has pantetheine-phosphate adenylyltransferase activity %3B in Dictyostelium%2C the latter activity is encoded by %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0288465%22%3E%3Ci%3EDDB_G0288465%3C%2Fi%3E%3C%2Fa%3E
chr4	3345269	3346553	+	DDB_G0285527	uch2	catalyzes the thiol-dependent hydrolysis of ester%2C thiolester%2C amide%2C peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin%3B most closely related to human BAP1 and UCHL5 genes
chr4	3346712	3347860	+	DDB_G0285529	DDB_G0285529	NA
chr4	3348010	3349209	+	DDB_G0285531	DDB_G0285531	NA
chr4	3349371	3350478	-	DDB_G0285533	ppt1	ortholog of the human PPT1%2C an enzyme which catalyzes the reaction: palmitoyl-protein %2B H%3Csub%3E2%3C%2Fsub%3EO %3D palmitate %2B protein%3B defects in PPT1 are the cause of infantile neuronal ceroid lipofuscinosis 1%2C a progressive neurodegenerative disease
chr4	3350719	3352212	-	DDB_G0285535	DDB_G0285535	NA
chr4	3352785	3354349	-	DDB_G0285537	ost3	subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of S. cerevisiae OST3 and human N33 (tumor suppressor candidate 3)%3B contains four C-terminal transmembrane domain and an N-terminal signal peptide
chr4	3354945	3356519	+	DDB_G0285539	DDB_G0285539	NA
chr4	3356593	3357897	-	DDB_G0285541	DDB_G0285541	putative family member of integral membrane proteins that are found to increase tolerance to divalent metal ions such as cadmium%2C zinc%2C and cobalt%3B contains 5 predicted transmembrane domains
chr4	3358729	3360093	+	DDB_G0285429	purA	catalyzes the reaction L-aspartate %2B IMP %2B GTP %3C%3D%3E adenylo-succinate %2B phosphate %2B GDP in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis
chr4	3360351	3361857	+	DDB_G0285749	DDB_G0285749	NA
chr4	3362096	3364252	+	DDB_G0285543	DDB_G0285543	NA
chr4	3364611	3365173	-	DDB_G0285545	DDB_G0285545	similar to  H. sapiens solute carrier family 31 member 1 (SLC31A1) or high affinity copper uptake protein 1%3B contains 3 predicted transmembrane domains
chr4	3366227	3366309	+	DDB_G0295179	tRNA-Tyr-GUA-5	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3366450	3367341	+	DDB_G0285547	DDB_G0285547_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3367805	3370093	+	DDB_G0285751	DDB_G0285751	NA
chr4	3370790	3371040	+	DDB_G0285549	DDB_G0285549	NA
chr4	3371635	3371898	+	DDB_G0285551	DDB_G0285551	NA
chr4	3372094	3373198	-	DDB_G0285553	cycL	similar to metazoan and higher plants cyclin L%2Fania-6%3B predicted to interact with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283279%22%3E%3Ci%3Ecdk11%3C%2Fi%3E%3C%2Fa%3E
chr4	3373704	3375482	+	DDB_G0285555	DDB_G0285555	highly similar to neighboring gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285419%22%3E%3Ci%3EcryS%3C%2Fi%3E%3C%2Fa%3E%3B contains a predicted signal peptide
chr4	3375645	3377390	-	DDB_G0285419	cryS	NA
chr4	3378778	3379617	+	DDB_G0285557	DDB_G0285557	NA
chr4	3380070	3384039	+	DDB_G0285559	DDB_G0285559	NA
chr4	3385002	3385755	+	DDB_G0285561	rps15	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S15 homolog
chr4	3385916	3386767	-	DDB_G0285563	DDB_G0285563	NA
chr4	3388026	3388566	+	DDB_G0285753	DDB_G0285753_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0286861%22%3EDDB_G0286861%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0294589%22%3EDDB_G0294589%3C%2Fa%3E
chr4	3389420	3391713	+	DDB_G0285565	DDB_G0285565_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271042%22%3EDDB_G0271042%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0275659%22%3EDDB_G0275659%3C%2Fa%3E
chr4	3392571	3392862	-	DDB_G0285567	DDB_G0285567	related to the hssA genes
chr4	3393304	3393774	+	DDB_G0285569	DDB_G0285569	NA
chr4	3393941	3394702	-	DDB_G0285755	DDB_G0285755_ps	putative pseudogene%3B similar to cyclin-like F-box containing proteins
chr4	3394833	3395356	+	DDB_G0285573	DDB_G0285573_ps	putative pseudogene%3B similar to short-chain dehydrogenase%2Freductase (SDR) family proteins
chr4	3395637	3396818	+	DDB_G0285575	alkB	ortholog of the conserved AlkB protein that repairs alkylation damage to DNA
chr4	3396934	3398208	-	DDB_G0285577	DDB_G0285577	NA
chr4	3398560	3401875	-	DDB_G0285579	nup107	component of the nuclear pore complex%2C which plays a role in RNA export
chr4	3402388	3406627	-	DDB_G0285581	DDB_G0285581	NA
chr4	3406976	3407301	+	DDB_G0285757	DDB_G0285757_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene  %3Ca href%3D%22%2Fgene%2FDDB_G0285837%22%3EDDB_G0285837%3C%2Fa%3E
chr4	3409194	3409475	-	DDB_G0285583	DDB_G0285583	NA
chr4	3409926	3413089	-	DDB_G0285585	DDB_G0285585	NA
chr4	3413814	3414983	-	DDB_G0285587	DDB_G0285587	NA
chr4	3415704	3419613	+	DDB_G0285589	forH	required for filopodia formation and maintenance through removal of capping protein and actin polymerization%3B also important for spherical cell morphology and resulting pseudopod orientation towards a cAMP gradient 
chr4	3421735	3422583	-	DDB_G0285591	cmbl	NA
chr4	3423740	3425574	+	DDB_G0285759	mmetS	catalyzes the reaction ATP %2B L-methionine %2B tRNAMet %3D AMP %2B diphosphate %2B L-methionyl-tRNAMet
chr4	3425659	3426687	-	DDB_G0285593	nfu1	ortholog of S. cerevisiae NFU1%2C involved in iron metabolism in mitochondria
chr4	3427765	3428337	+	DDB_G0285595	DDB_G0285595	weakly similar to E. coli yecM
chr4	3428530	3429424	-	DDB_G0285597	rps28	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S28 homolog
chr4	3430845	3432486	+	DDB_G0285599	mcfB	similar to the %3Ci%3EH. sapiens%3C%2Fi%3E calcium-dependent mitochondrial aspartate and glutamate carriers SLC25A24 and SLC25A25%3B contains two EF-hands%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr4	3433247	3434746	+	DDB_G0285601	cdc20	ortholog of CDC20%3B a cell-cycle regulated activator of anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C which is required for metaphase%2Fanaphase transition%3B directs ubiquitination of mitotic cyclins
chr4	3435392	3435559	+	DDB_G0285603	DDB_G0285603	NA
chr4	3436262	3437972	-	DDB_G0285761	DDB_G0285761	contains a growth factor receptor domain%3B contains a predicted signal peptide and a putative C-terminal transmembrane domain
chr4	3439404	3440564	+	DDB_G0285763	DDB_G0285763	NA
chr4	3440715	3443406	-	DDB_G0285427	mkcA	similar to MAP cascade kinases belonging to the PAK sub-family of the STE20 serine%2Fthreonine kinases%3B partial suppressor of tagB mutation
chr4	3445107	3447452	-	DDB_G0285765	DDB_G0285765	NA
chr4	3448354	3453192	+	DDB_G0285767	DDB_G0285767	NA
chr4	3453352	3454713	-	DDB_G0285605	DDB_G0285605	NA
chr4	3454900	3455985	-	DDB_G0285607	DDB_G0285607	NA
chr4	3456501	3458534	-	DDB_G0285609	DDB_G0285609	NA
chr4	3459087	3460253	+	DDB_G0285611	DDB_G0285611	NA
chr4	3460993	3462417	-	DDB_G0285769	DDB_G0285769	highly similar to agglutinin domain-containing protein %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285617%22%3E%3Ci%3EDDB_G0285617%3C%2Fi%3E%3C%2Fa%3E (80%25 identity)%3B contains a signal peptide
chr4	3463966	3465387	+	DDB_G0285613	DDB_G0285613	contains an N-terminal heat shock domain and 3 putative transmembrane domains in the C-terminal half
chr4	3466396	3468270	+	DDB_G0285729	DDB_G0285729	contains a putative signal peptide
chr4	3469352	3470119	+	DDB_G0285615	iliA	contains a putative N-terminal signal sequence%3B regulated by %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0272110%22%3EgskA%3C%2Fa%3E and %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0285615%22%3EzakA%3C%2Fa%3E%2C and induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr4	3471998	3473428	+	DDB_G0285617	DDB_G0285617	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285769%22%3E%3Ci%3EDDB_G0285769%3C%2Fi%3E%3C%2Fa%3E (80%25 identity)%3B contains a signal peptide
chr4	3474787	3475530	+	DDB_G0285619	DDB_G0285619	NA
chr4	3475963	3477627	+	DDB_G0285621	DDB_G0285621	conserved Dictyostelium protein%3B contains a putative signal sequence and one C-terminal transmembrane domain
chr4	3478635	3480047	+	DDB_G0285771	DDB_G0285771	NA
chr4	3480410	3481210	-	DDB_G0285623	DDB_G0285623	NA
chr4	3482506	3484356	-	DDB_G0285773	DDB_G0285773	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%3B contains one putative transmembrane domain
chr4	3485870	3486019	+	DDB_G0285625	hdaC_ps2	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0280195%22%3E%3Ci%3EhdaC%3C%2Fi%3E%3C%2Fa%3E
chr4	3486954	3488375	+	DDB_G0285627	DDB_G0285627	NA
chr4	3488592	3489392	-	DDB_G0285629	DDB_G0285629	NA
chr4	3490502	3492259	-	DDB_G0285775	DDB_G0285775	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%3B contains one putative transmembrane domain
chr4	3493674	3495545	-	DDB_G0285631	DDB_G0285631	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%3B contains one putative transmembrane domain and an additional putative signal sequence
chr4	3496907	3497686	+	DDB_G0285633	DDB_G0285633	NA
chr4	3498174	3501384	-	DDB_G0285635	DDB_G0285635	NA
chr4	3503514	3504284	+	DDB_G0285791	DDB_G0285791	NA
chr4	3504616	3506448	+	DDB_G0285423	DG2044	NA
chr4	3507070	3507243	-	DDB_G0285779	DDB_G0285779	NA
chr4	3508114	3508581	+	DDB_G0285781	DDB_G0285781	contains putative N-terminal signal peptide
chr4	3508802	3509885	+	DDB_G0285783	ndufa12	accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)
chr4	3510010	3512490	-	DDB_G0285637	glb2	belongs to glycoside hydrolase family 35%3B hydrolyzes terminal non-reducing beta-D-galactose residues in beta-D-galactoside%3B has a signal peptide
chr4	3514189	3517814	+	DDB_G0285421	DDB_G0285421	has a signal peptide followed by a transmembrane domain%3B conserved in D. purpureum and P. pallidum
chr4	3518236	3518697	+	DDB_G0285639	DDB_G0285639	contains one ML (MD-2-related lipid recognition) domain%3B similar to fungal proteins of the NPC2 family%3B contains a predicted signal peptide
chr4	3519879	3522690	+	DDB_G0285641	gacJ	NA
chr4	3523048	3525270	-	DDB_G0285643	mrkB	CAMKL family protein kinase%2C similar to SNF1 kinases%2C MARK kinases%2C and AMPK kinases
chr4	3526607	3526907	-	DDB_G0285787	DDB_G0285787	NA
chr4	3531932	3533242	-	DDB_G0285645	DDB_G0285645	NA
chr4	3533871	3535958	+	DDB_G0285647	nagE	similar to beta-hexosaminidase%2C but shorter on the amino terminus
chr4	3536200	3537509	-	DDB_G0285649	DDB_G0285649	the protein phosphatase 2C-related domain occurs in protein phosphatase 2C (PPC2) as well as in other proteins%2C such as pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase
chr4	3541732	3542967	+	DDB_G0285425	gpaD	subunit of the heterotrimeric G protein that has GTPase activity%3B involved in the chemotactic response to folate
chr4	3544377	3544642	-	DDB_G0285651	DDB_G0285651	NA
chr4	3545567	3547171	+	DDB_G0285653	DDB_G0285653	NA
chr4	3547353	3550847	-	DDB_G0285655	DDB_G0285655	NA
chr4	3551340	3552992	+	DDB_G0285657	DDB_G0285657	NA
chr4	3553333	3554032	+	DDB_G0285659	DDB_G0285659	NA
chr4	3554545	3558120	-	DDB_G0285663	DDB_G0285663	conserved protozoa protein that are putative permeases involved in the transport of lipids%3B contains 10 putative transmembrane domains
chr4	3559137	3559350	+	DDB_G0295823	DDB_G0295823	NA
chr4	3559921	3563643	-	DDB_G0285665	DDB_G0285665	NA
chr4	3564751	3568344	-	DDB_G0285667	DDB_G0285667	NA
chr4	3569277	3573032	-	DDB_G0285669	DDB_G0285669	NA
chr4	3574096	3574724	-	DDB_G0285671	DDB_G0285671	NA
chr4	3575039	3575088	+	DDB_G0295601	r34	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr4	3575375	3575629	-	DDB_G0285673	DDB_G0285673	contains two C2H2 type Zn-fingers
chr4	3576296	3577069	+	DDB_G0285675	DDB_G0285675	NA
chr4	3577440	3581748	+	DDB_G0285677	DDB_G0285677	NA
chr4	3582121	3583854	+	DDB_G0285679	nol5a	ortholog of H. sapiens NOL5A and S. cerevisiae SIK1%3B SIK1 is a component of the box C%2FD snoRNP complex involved in rRNA processing
chr4	3584332	3585281	-	DDB_G0285681	DDB_G0285681	NA
chr4	3586013	3588128	-	DDB_G0285683	eif3I	EIF3I ortholog%2C the eukaryotic initiation factor beta subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr4	3590065	3591549	+	DDB_G0285685	DDB_G0285685	NA
chr4	3591605	3592945	-	DDB_G0285687	DDB_G0285687	NA
chr4	3593584	3595491	-	DDB_G0285689	DDB_G0285689	NA
chr4	3596207	3597379	+	DDB_G0285691	DDB_G0285691	NA
chr4	3597715	3600552	+	DDB_G0285693	DDB_G0285693	NA
chr4	3600764	3602423	-	DDB_G0285695	DDB_G0285695	conserved in Dictyostelium%3B contains weak match to FNIP repeat regions
chr4	3603409	3604797	+	DDB_G0285697	DDB_G0285697	NA
chr4	3605127	3606965	+	DDB_G0285699	DDB_G0285699	NA
chr4	3607268	3609916	+	DDB_G0285701	DDB_G0285701	NA
chr4	3610989	3614073	+	DDB_G0285703	hipA	clathrin-associated protein involved in spore coat formation and regulated by epsin%3B contains an Epsin N-terminal homology domain (ENTH)%2C and a C-terminal I%2FLWEQ domain that has been shown to bind to F-actin
chr4	3615364	3619240	+	DDB_G0285705	DDB_G0285705	contains a RING-finger that is a specialised type of Zn-finger domain%2C which in some cases has been shown to be involved in ubiquitin E3 ligase activity%3B contains 14 putative transmembrane domains
chr4	3619487	3622099	+	DDB_G0285707	DDB_G0285707	NA
chr4	3622848	3624630	+	DDB_G0285709	DDB_G0285709	NA
chr4	3625722	3626918	+	DDB_G0285711	DDB_G0285711	the phox domain has been associated with diverse functions such as cell signalling%2C vesicular trafficking%2C protein sorting and lipid modification%2C and the C2 domain is a Ca2%2B-dependent membrane-targeting module found in many cellular proteins involved in signal transduction or membrane trafficking%3B similar to D. purpureum protein
chr4	3627427	3628762	+	DDB_G0285417	cdk7	putative ortholog of CDK7 and CTK1%2C which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit%3B predicted to be activated by %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2F%2Fgene_page.pl?gene_name%3DcycH%22%3Ecyclin H%3C%2Fa%3E
chr4	3629117	3630074	+	DDB_G0285713	med18	ortholog of the mediator of RNA polymerase II transcription subunit 18%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr4	3630133	3631005	-	DDB_G0285715	DDB_G0285715	NA
chr4	3631211	3632094	-	DDB_G0285717	gloB1	catalyzes the reaction S-lactoyl-glutathione %2B H2O %3C%3D%3E reduced glutathione %2B D-lactate
chr4	3632780	3632992	+	DDB_G0285721	DDB_G0285721	NA
chr4	3633398	3635701	-	DDB_G0285723	DDB_G0285723	NA
chr4	3636502	3637632	+	DDB_G0285725	dhps	catalyzes the first step in the formation of deoxyhypusine: [eIF5A]-lysine %2B spermidine %3D [eIF5A]-deoxyhypusine %2B propane-1%2C3-diamine%2C an essential post-translational modification only found in mature eIF5A factor%3B the second reaction is catalyzed by Dohh 
chr4	3638134	3655523	+	DDB_G0285797	DDB_G0285797	NA
chr4	3656149	3656978	+	DDB_G0285793	cadA	calcium-dependent cell-cell adhesion protein%3B lacks a signal sequence and is transported through the contractile vacuole to the plasma membrane for either secretion or cell surface presentation%3B abcb4 has been identified as the anchor on the membrane%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse the cadA gene encoding a calcium-dependent cell adhesion molecule with the cadA locus associated with resistance to cadmium (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Freference%2Freference.pl?refNo%3D6757%22%3EWelker and Deering 1978%3C%2Fa%3E)
chr4	3658459	3658541	+	DDB_G0295181	tRNA-Tyr-GUA-6	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3658983	3659882	+	DDB_G0285795	DDB_G0285795_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3661035	3662987	+	DDB_G0285835	DDB_G0285835_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3663997	3665463	+	DDB_G0285799	DDB_G0285799	NA
chr4	3665650	3666684	+	DDB_G0285801	DDB_G0285801	contains a predicted signal peptide an a carboxy-terminal transmembrane domain
chr4	3666930	3672240	-	DDB_G0295485	DDB_G0295485	NA
chr4	3673056	3673826	+	DDB_G0285803	DDB_G0285803	belongs to the GNAT family%3B homolog of S. cerevisiae MAK3 (maintenance of killer protein 3)
chr4	3674059	3680821	-	DDB_G0285837	DDB_G0285837	member of the bromo-WD repeat (BRWD) class of chromatin assembly proteins
chr4	3681493	3684021	+	DDB_G0285805	DDB_G0285805	NA
chr4	3684831	3685211	+	DDB_G0285833	DDB_G0285833	NA
chr4	3686003	3686739	+	DDB_G0285807	DDB_G0285807	contains a putative signal peptide
chr4	3686858	3687620	-	DDB_G0285811	DDB_G0285811	NA
chr4	3688403	3690416	+	DDB_G0285813	DDB_G0285813	belongs to the DUF812 family%3B homolog of human CCDC22 (coiled-coil domain-containing protein 22)%3B contains at least two coiled-coil domains
chr4	3691117	3695040	+	DDB_G0285815	gpt1	very similar to the mammalian N-acetylglucosamine-1-phosphotransferase alpha%2Fbeta subunit (GNPTAB) precursor%3B a central part of the Dictyostelium protein is not conserved%3B in humans%2C the precursor is cleaved and contributes to a %26alpha%3B2%26beta%3B2%26gamma%3B2 hexamer%3B the %26gamma%3B subunits%2C which are not required for catalytic activity%2C are encoded by a separate human gene not found in the D. discoideum and D. purpureum genomes
chr4	3695620	3696444	-	DDB_G0285817	cad3	very similar to cadA (cad1)%2C a calcium-binding cell-cell adhesion molecule
chr4	3698143	3699668	+	DDB_G0285839	DDB_G0285839	NA
chr4	3700169	3700595	+	DDB_G0285819	DDB_G0285819_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0295485%22%3EDDB_G0295485%3C%2Fa%3E 
chr4	3701203	3703163	+	DDB_G0285821	srp68	component of the signal recognition particle (SRP)%2C which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulum
chr4	3703536	3705269	+	DDB_G0285823	DDB_G0285823	NA
chr4	3705430	3706121	-	DDB_G0285825	DDB_G0285825	NA
chr4	3706474	3707930	+	DDB_G0285827	DDB_G0285827	NA
chr4	3708077	3709133	-	DDB_G0285829	bxdc5	ortholog of S. cerevisiae RPF1 and H. sapiens BXDC5%2C a nucleolar protein involved in the assembly of the large ribosomal subunit
chr4	3709396	3709917	+	DDB_G0285831	DDB_G0285831	NA
chr4	3710357	3710446	+	DDB_G0295183	tRNA-Thr-UGU-3	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3710715	3711253	+	DDB_G0285841	DDB_G0285841_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3715691	3716770	-	DDB_G0285951	DDB_G0285951_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3717164	3717253	-	DDB_G0295215	tRNA-Thr-UGU-4	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3717914	3718712	+	DDB_G0285851	DDB_G0285851	NA
chr4	3719511	3723808	+	DDB_G0285849	spc97	centrosomal protein involved in microtubule nucleation
chr4	3724070	3725418	-	DDB_G0285853	polA4	ortholog of the DNA primase small subunit of the DNA polymerase alpha-primase complex%2C required for the initiation of DNA replication
chr4	3725623	3726100	+	DDB_G0285855	dlcC	dynein is a multisubunit microtubule-dependent motor enzyme that acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules%3B belongs to the roadblock%2FLC7 family
chr4	3726406	3728660	-	DDB_G0285943	DDB_G0285943	ortholg of mammalian transmembrane protein 87A (TMEM87A)%3B contains seven transmembrane domains 
chr4	3730680	3733595	+	DDB_G0285859	gxcP	NA
chr4	3733661	3734953	-	DDB_G0285861	DDB_G0285861	NA
chr4	3736082	3736395	+	DDB_G0285863	DDB_G0285863	expressed in prespore cells
chr4	3737676	3740354	+	DDB_G0285865	DDB_G0285865	NA
chr4	3740816	3741082	-	DDB_G0285867	DDB_G0285867	expressed in pstO cells
chr4	3741819	3743117	-	DDB_G0285869	DDB_G0285869	NA
chr4	3743951	3745591	+	DDB_G0285953	DDB_G0285953	NA
chr4	3745815	3746620	-	DDB_G0285871	DDB_G0285871	ortholog of the conserved RAN guanine nucleotide release factor and S. cerevisiae MOG1 involved in nuclear protein import and nucleotide release
chr4	3747167	3747718	+	DDB_G0285873	DDB_G0285873	NA
chr4	3748302	3755437	+	DDB_G0285875	DDB_G0285875	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr4	3755842	3756930	-	DDB_G0285845	phdA	similar to Dictyostelium discoideum protein CRAC encoded by dagA gene
chr4	3759550	3759675	+	DDB_G0285945	DDB_G0285945	NA
chr4	3760460	3762734	+	DDB_G0285877	nadsyn1	catalyzes the reaction ATP %2B deamido-NAD%2B %2B L-glutamine %2B H%3Csub%3E2%3C%2Fsub%3EO %3D AMP %2B diphosphate %2B NAD%2B %2B L-glutamate
chr4	3762999	3764826	-	DDB_G0285879	DDB_G0285879	contains a predicted peroxisomal targeting signal
chr4	3767530	3773887	+	DDB_G0285955	DDB_G0285955	NA
chr4	3775456	3776276	+	DDB_G0285881	rpl18a	protein component of the large (60S) ribosomal subunit
chr4	3776481	3777896	-	DDB_G0285885	DDB_G0285885_ps	putative pseudogene%2C very similar to large%2C conserved family of Dictyostelium EGF-like domain-containing proteins
chr4	3778774	3779696	+	DDB_G0285887	DDB_G0285887	NA
chr4	3780014	3780967	+	DDB_G0285889	DDB_G0285889	NA
chr4	3781232	3787680	-	DDB_G0285891	gdt3_ps	putative pseudogene%3B member of the TKL (tyrosine kinase-like) group and the GDT family%3B belongs to the MLK protein kinase family
chr4	3788417	3789603	+	DDB_G0285893	DDB_G0285893	similar to other Dictyostelium hypothetical proteins%3B contains a putative signal peptide
chr4	3790076	3793854	-	DDB_G0285895	gdt5	highly similar to other Dictyostelium GDT proteins%2C however%2C it does not contain a protein kinase domain
chr4	3794131	3797177	-	DDB_G0285957	xpr1	ortholog of XPR1%2C which in mammals confers susceptibility to infection with murine leukaemia viruses%3B also similar to yeast SYG1%2C a G-protein associated signal transduction protein%2C and plant PHO1%2C that may be involved in phosphate transport
chr4	3798877	3800675	+	DDB_G0285897	DDB_G0285897	NA
chr4	3800826	3802564	-	DDB_G0285899	DDB_G0285899	catalyzes the reaction L-alanine %2B 2-oxoglutarate %3C%3D%3E pyruvate %2B L-glutamate
chr4	3805604	3808315	+	DDB_G0285901	DDB_G0285901	contains a Vps53-like%2C N-terminal domain%3B Vps53 complexes with Vps52 and Vps54 to form a multi-subunit complex which might be involved in regulating membrane trafficking events
chr4	3808445	3809360	-	DDB_G0285903	DDB_G0285903	NA
chr4	3809647	3810575	-	DDB_G0285905	DDB_G0285905	NA
chr4	3810828	3812441	-	DDB_G0285907	DDB_G0285907	related to the Ovarian Tumour (OTU) gene of Drosophila%3B function is unknown but conserved cysteine and histidine%2C and possibly the aspartate%2C residues suggests that those not yet recognized as peptidases could possess cysteine protease activity
chr4	3812938	3813739	+	DDB_G0285909	DDB_G0285909	catalyzes the removal of a phosphate group attached to a tyrosine residue%3B ortholog of S. cerevisiae SIW14 that plays a role in actin filament organization and endocytosis
chr4	3814964	3818222	+	DDB_G0285911	DDB_G0285911	NA
chr4	3818293	3821817	-	DDB_G0285913	DDB_G0285913	NA
chr4	3822394	3825306	-	DDB_G0285915	gacK	NA
chr4	3827611	3828228	-	DDB_G0285917	DDB_G0285917	NA
chr4	3828991	3830143	-	DDB_G0285919	DDB_G0285919	homolog of human TIPRL and S. cerevisiae TIP41 (TAP42-interacting protein 1)%3B TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway%3B TIPRL is a putative MAPK-activating protein
chr4	3830484	3831749	+	DDB_G0285921	mmm1	similar to S. cerevisiae MMM1 (maintenance of mitochondrial morphology protein 1)%3B MMM1 is a component of the endoplasmic reticulum-mitochondria encounter structure which is essential for maintaining the structure of mitochondria%3B contains one putative transmembrane domain
chr4	3831998	3834469	-	DDB_G0285923	DDB_G0285923	NA
chr4	3835569	3839405	+	DDB_G0285925	sunB	SUN-like protein with a centrally located domain%3B contains a predicted N-terminal signal sequence
chr4	3839546	3840504	-	DDB_G0285927	DDB_G0285927	similar to Bacillus subtilis sfp%3B transfers the 4%27-phosphopantetheine moiety from coenzyme A to a serine residue of acyl carrier proteins specific to Type I multifunctional PKS%2Ffatty acid synthase proteins   
chr4	3842242	3844554	+	DDB_G0285959	DDB_G0285959	NA
chr4	3845153	3845398	-	DDB_G0285929	DDB_G0285929	NA
chr4	3845828	3850119	+	DDB_G0285961	rfc1	ortholog of %3Ci%3EH. sapiens%3C%2Fi%3E RFC 140 kDa subunit
chr4	3850259	3852868	-	DDB_G0285931	dlpB	NA
chr4	3854532	3857501	+	DDB_G0285933	DDB_G0285933	NA
chr4	3858078	3859821	+	DDB_G0285847	rbbE	similar to H. sapiens Retinoblastoma binding protein RBBP5
chr4	3859998	3860462	-	DDB_G0285935	DDB_G0285935	NA
chr4	3861549	3865824	-	DDB_G0285843	helD	conserved RNA helicase%3B S. cerevisiae prp16 involved in the second catalytic step of splicing%2C exhibits ATP-dependent RNA unwinding activity
chr4	3866187	3869507	+	DDB_G0285937	dhx16	DEAD%2FDEAH box helicases are involved in various aspects of RNA metabolism including nuclear pre-mRNA splicing
chr4	3870921	3873575	+	DDB_G0285939	ctnnA	catenin%2Fvinculin family protein%3B binds to aardvark%2C the Dictyostelium beta-catenin related protein%3B required for the formation of a polarized epithelium at the culminant tip and thus for stalk formation during culmination
chr4	3873726	3875188	-	DDB_G0285941	DDB_G0285941	NA
chr4	3876403	3878652	-	DDB_G0285963	fhkD	CAMK group%2C RAD53 family protein kinase%3B similar to mammalian cell cycle checkpoint kinases chk2%3B contains a forkhead-associated (FHA) domain%2C a phosphopeptide recognition domain found in many regulatory proteins
chr4	3879686	3880541	-	DDB_G0285965	DDB_G0285965	contains a AWS domain (Associated With SET)%3B but not SET domain%3B contains a signal peptide and a C-terminal transmembrane domain
chr4	3881074	3884386	-	DDB_G0285967	lpten	tensin family protein (related to the tumor suppressor PTEN)%3B contains a lipid phosphatase domain%2C a C2-like domain%2C and 5 C-terminal LIM domains (absent from PTEN)
chr4	3885433	3886050	-	DDB_G0285969	DDB_G0285969	putative cysteine protease%3B member of the DJ-1%2FThiJ%2FPfpI family%2C which includes human PARK7 associated with Parkinson%27s disease
chr4	3886590	3887209	+	DDB_G0285971	rpl37	protein component of the large ribosomal subunit
chr4	3894503	3895906	+	DDB_G0285973	DDB_G0285973	NA
chr4	3896573	3899326	+	DDB_G0285975	DDB_G0285975	NA
chr4	3899815	3900842	+	DDB_G0285979	DDB_G0285979_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0285975%22%3EDDB_G0285975%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0285981%22%3EDDB_G0285981%3C%2Fa%3E
chr4	3901446	3903941	+	DDB_G0285981	DDB_G0285981	similar to the vertebrate loss of heterozygosity 11%2C chromosomal region 2%2C gene A
chr4	3904475	3905183	-	DDB_G0285983	DDB_G0285983	NA
chr4	3906524	3907663	-	DDB_G0285985	DDB_G0285985	contains 7 predicted transmembrane domains%3B very similar to D. purpureum protein
chr4	3908514	3909947	-	DDB_G0285987	DDB_G0285987	NA
chr4	3911476	3915180	+	DDB_G0285989	DDB_G0285989	NA
chr4	3915272	3916373	-	DDB_G0285991	DDB_G0285991	NA
chr4	3918232	3919175	+	DDB_G0285999	cnbB	contains 3 EF-hands%2C similar to calcineurin B (cnbA)%2C the regulatory subunit of the Ca2%2B%2Fcalmodulin-dependent serine%2Fthreonine protein phosphatase
chr4	3919822	3919893	-	DDB_G0295213	tRNA-Asp-GUC-15	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr4	3920731	3921727	+	DDB_G0286001	DDB_G0286001	NA
chr4	3922084	3924210	-	DDB_G0285997	abcF1	consists of two ABC domains and lacks a transmembrane domain
chr4	3925023	3929117	+	DDB_G0286003	DDB_G0286003	similar to many uncharacterized Dictyostelium leucine-rich repeat-containing proteins
chr4	3929775	3931286	-	DDB_G0285995	pdsA	NA
chr4	3939784	3940347	-	DDB_G0286007	rbm8A	conserved protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance%3B the human ortholog has been shown to interact with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270866%22%3E%3Ci%3Emagoh%3C%2Fi%3E%3C%2Fa%3E
chr4	3940845	3941717	+	DDB_G0286009	tmem33	NA
chr4	3942404	3942475	+	DDB_G0295185	tRNA-Asp-GUC-14	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr4	3944436	3945295	-	DDB_G0286101	DDB_G0286101_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	3945723	3945804	-	DDB_G0295211	tRNA-Ser-UGA-7	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3946482	3947271	-	DDB_G0286017	DDB_G0286017_ps	putative pseudogene%3B similar to ubiquitin domain-containing proteins%2C especially %3Ca href%3D%22%2Fgene%2FDDB_G0286031%22%3EubqP%3C%2Fa%3E
chr4	3947721	3947793	-	DDB_G0295209	tRNA-Ala-AGC-8	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3948218	3949552	+	DDB_G0286097	DDB_G0286097_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr4	3951359	3952914	-	DDB_G0286015	gmsA	homologous to the Chlamydomonas reinhardtii a2gene%3B enriched in gametes
chr4	3953660	3954522	+	DDB_G0286021	DDB_G0286021	NA
chr4	3954952	3955322	-	DDB_G0286023	DDB_G0286023	NA
chr4	3955941	3959710	-	DDB_G0286013	repE	ortholog of H. sapiens %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0286013%22%3E%3Ci%3ErepE%3C%2Fi%3E%3C%2Fa%3E%2FXPE%3B mutated in patients with xeroderma pigmentosum%3B interacts with detA
chr4	3960039	3961587	+	DDB_G0286011	alg1	CAZy family GT33%3B catalyzes N-linked mannosylation
chr4	3961629	3962211	-	DDB_G0286103	DDB_G0286103	NA
chr4	3964324	3965976	+	DDB_G0286025	DDB_G0286025	similar to bacterial cellulase celA%3B expressed in pstAB%2C pstA%2C and pstO cells
chr4	3966261	3967572	+	DDB_G0286027	rfc4	ortholog of %3Ci%3EH. sapiens%3C%2Fi%3E RFC4 (37 kDa subunit) and %3Ci%3ES. cerevisiae%3C%2Fi%3E RFC2
chr4	3967753	3968240	-	DDB_G0286029	DDB_G0286029_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene  %3Ca href%3D%22%2Fgene%2FDDB_G0288499%22%3EDDB_G0288499%3C%2Fa%3E
chr4	3970863	3970935	+	DDB_G0295187	tRNA-Lys-UUU-14	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr4	3971817	3972755	-	DDB_G0286031	ubqP	NA
chr4	3973237	3975427	-	DDB_G0286033	pex5	ortholog of peroxin 5%2C peroxisomal membrane signal receptor for C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins%2C required for peroxisomal matrix protein import%3Bmutations in human homolog cause a variety of peroxisomal disorders
chr4	3976133	3980036	+	DDB_G0286035	mcm9	similar to H. sapiens MCM9
chr4	3980260	3981591	-	DDB_G0286105	DDB_G0286105	similar to D. purpureum protein
chr4	3983688	3984515	+	DDB_G0286109	DDB_G0286109	similar to latrophilin-like receptor lrlA%2C a G-protein-coupled receptor (GPCR) family protein%3B contains four predicted transmembrane domains and is significantly shorter than lrlA
chr4	3985122	3986208	+	DDB_G0286037	lrlA	similar to latrophilins that are a family of secretin-like G-protein-coupled receptors (GPCRs)%3B contains 7 putative transmembrane domains
chr4	3986273	3987355	-	DDB_G0286039	DDB_G0286039	NA
chr4	3987715	3989124	-	DDB_G0286041	iliJ	contains a central%2C large T4 RNA ligase%2C RnlA-like domain%2C a property shared by a related gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0289211%22%3EDDB_G0289211%3C%2Fa%3E%3B similar to D. purpureum protein%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr4	3989629	3991515	+	DDB_G0286043	DDB_G0286043	NA
chr4	3992727	3994952	+	DDB_G0286045	DDB_G0286045	one of many putative Dictyostelium potassium channels%3B contains 3 pentapeptide repeats
chr4	3995156	3995527	+	DDB_G0286047	DDB_G0286047	NA
chr4	3995640	3997332	-	DDB_G0286111	pigW	NA
chr4	3998261	3999466	+	DDB_G0286049	zntC	ZIP family zinc transporter%2C LZT subfamily member%3B contains 7 transmembrane domains%3B expressed in pstAB cells
chr4	3999753	4001300	-	DDB_G0286051	leo1	component of the conserved Paf1 complex%2C a multifunctional complex%2C involved in histone methylation and plays a role in RNA elongation and processing
chr4	4001619	4002456	-	DDB_G0286053	DDB_G0286053	NA
chr4	4003428	4004991	+	DDB_G0286055	DDB_G0286055	conserved in Dictyostelids%2C contains also a SCP-like extracellular domain
chr4	4005558	4006839	+	DDB_G0286057	adk	catalyzes the reaction ATP %2B adenosine %3C%3D%3E ADP %2B AMP
chr4	4007481	4009238	-	DDB_G0286059	asns	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B L-glutamine %2B L-aspartate %2B ATP -%3E L-glutamate %2B L-asparagine %2B pyrophosphate %2B AMP
chr4	4010233	4011861	-	DDB_G0286061	DDB_G0286061	has similarity to bacterial cellulase celA
chr4	4014322	4015437	-	DDB_G0286063	DDB_G0286063	contains 7 predicted transmembrane domains
chr4	4016707	4018260	+	DDB_G0286065	DDB_G0286065	NA
chr4	4019113	4022817	+	DDB_G0286067	DDB_G0286067	NA
chr4	4023180	4025992	+	DDB_G0286069	ku70	part of the heterodimer ku70%2Fku80 complex%2C which binds to DNA double-strand break ends%3B  involved in double-strand break repair via nonhomologous end joining (NHEJ)
chr4	4026106	4026533	-	DDB_G0286071	DDB_G0286071	similar to D. purpureum protein
chr4	4028900	4030537	+	DDB_G0286073	DDB_G0286073	similar to D. purpureum protein
chr4	4031568	4032398	+	DDB_G0286075	rps5	protein component of the small (40S) ribosomal subunit
chr4	4032914	4033347	+	DDB_G0286077	commd6	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr4	4034365	4036020	-	DDB_G0286079	DDB_G0286079	NA
chr4	4036084	4037314	-	DDB_G0286081	DDB_G0286081	NA
chr4	4038588	4039073	+	DDB_G0286083	DDB_G0286083	the SWIM domain is found in variety of prokaryotic and eukaryotic proteins%3B it is predicted to have DNA-binding and protein-protein interaction functions in different contexts%3B similar to D. purpureum protein
chr4	4039412	4040767	-	DDB_G0286085	DDB_G0286085	NA
chr4	4041102	4041290	+	DDB_G0286087	DDB_G0286087	NA
chr4	4041536	4043038	-	DDB_G0286089	DDB_G0286089	similar to D. purpureum protein
chr4	4044149	4045164	+	DDB_G0286113	DDB_G0286113_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0269802%22%3EDDB_G0269802%3C%2Fa%3E
chr4	4045722	4050106	+	DDB_G0286091	DDB_G0286091	NA
chr4	4051045	4055036	+	DDB_G0286115	DDB_G0286115	PIP5K catalyze the formation of phosphoinositol-4%2C5-bisphosphate via the phosphorylation of phosphatidylinositol-4-phosphate%2C a precursor in the phosphinositide signaling pathway
chr4	4055353	4055829	-	DDB_G0286093	DDB_G0286093	NA
chr4	4056446	4058583	+	DDB_G0286095	plbC	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0276767%22%3E%3Ci%3EplbA%3C%2Fi%3E%3C%2Fa%3E%2C which catalyzes the hydrolysis of phosphatidylcholine to glycerophosphocholine
chr4	4060377	4062677	+	DDB_G0286129	DDB_G0286129	similar to mammalian F-box%2FWD repeat-containing protein 7%2C which is part to the E3 ubiquitin-protein ligase complex
chr4	4062977	4064214	-	DDB_G0286169	rabZ	NA
chr4	4064803	4067352	-	DDB_G0286131	sec63	similar to the widely conserved SEC63%2C which seems to be required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane
chr4	4067973	4070792	-	DDB_G0286125	pkgC	serine%2Fthreonine protein kinase of the AGC group%2C similar to mammalian ribosomal  protein S6 kinase
chr4	4072416	4073194	-	DDB_G0286117	rps10	protein component of the small (40S) ribosomal subunit%3B highly expressed in vegetative cells and in early development
chr4	4074134	4075129	+	DDB_G0286133	DDB_G0286133	NA
chr4	4075230	4076550	-	DDB_G0286135	DDB_G0286135	similar to Homo sapiens ZZZ3 protein
chr4	4077065	4077451	+	DDB_G0286181	romo1	conserved mitochondrial protein%2C ROMO1 in H. sapiens and MGR2 (Mitochondrial Genome Required) in S. cerevisiae%2C involved in reactive oxygen species production%3B contains 2 predicted transmembrane domains
chr4	4078435	4083912	+	DDB_G0286123	tagD	amino terminus has a serine protease domain%2C carboxy terminus consists of a half-transporter of the ABCB family
chr4	4085057	4090282	+	DDB_G0286121	tagC	amino terminus has a serine protease domain%2C carboxy terminus consists of a half-transporter of the ABCB family
chr4	4091463	4097183	+	DDB_G0286119	tagB	protease%2C processes the SDF-1 precursor to generate the active SDF-1 peptide
chr4	4097397	4098012	-	DDB_G0286171	uqcrb	ortholog of mammalian UQCRB%2C a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is part of the mitochondrial respiratory chain
chr4	4103161	4104872	+	DDB_G0286173	DDB_G0286173	NA
chr4	4105304	4107075	+	DDB_G0286165	DDB_G0286165	NA
chr4	4107413	4110603	+	DDB_G0286137	DDB_G0286137	ortholog of human HPS1%3B mutations in human HPS1 have been linked to Hermansky-Pudlak syndrome 1
chr4	4110771	4111445	-	DDB_G0286139	DDB_G0286139	NA
chr4	4112361	4118101	-	DDB_G0286127	roco8	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains DEP%2C LRR%2C Roc%2C COR%2C and protein kinase domains
chr4	4119612	4121103	-	DDB_G0286167	DDB_G0286167	NA
chr4	4121354	4121800	-	DDB_G0286141	DDB_G0286141	NA
chr4	4122107	4123371	-	DDB_G0286175	DDB_G0286175	NA
chr4	4126891	4128029	+	DDB_G0286143	DDB_G0286143	NA
chr4	4130109	4131316	+	DDB_G0286145	DDB_G0286145	NA
chr4	4132037	4132766	+	DDB_G0286147	pfdn6	component of the prefoldin complex responsible for targeting proteins to cytosolic chaperonin CCT
chr4	4132917	4134488	-	DDB_G0286149	dnpep	NA
chr4	4135325	4137154	+	DDB_G0286151	DDB_G0286151	similar to H. sapiens solute carrier family 2%2C facilitated glucose transporter member 1 (SLC2A1)
chr4	4137733	4140501	+	DDB_G0286153	DDB_G0286153	NA
chr4	4140756	4144792	+	DDB_G0286155	DDB_G0286155_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0286947%22%3EDDB_G0286947%3C%2Fa%3E
chr4	4145918	4147268	+	DDB_G0286157	DDB_G0286157	NA
chr4	4147632	4150879	+	DDB_G0286177	DDB_G0286177_ps	putative pseudogene%3B similar to %3Ci%3ED. discoideum%3C%2Fi%3E gene %3Ca href%3D%22%2Fgene%2FDDB_G0286673%22%3E DDB_G0286673%3C%2Fa%3E
chr4	4151188	4151864	-	DDB_G0286159	nudc	conserved protein required for nuclear movement
chr4	4152139	4153407	+	DDB_G0286161	DDB_G0286161	NA
chr4	4153623	4155652	-	DDB_G0286163	DDB_G0286163	NA
chr4	4157569	4158198	-	DDB_G0295733	DDB_G0295733	NA
chr4	4158602	4159795	-	DDB_G0294631	DDB_G0294631	similar to Entamoeba histolytica XP_650568%3B contains no conserved functional domains
chr4	4160391	4160692	-	DDB_G0286193	DDB_G0286193	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstAO cells
chr4	4161180	4163443	-	DDB_G0286195	nagB1	long version of the glucosamine-6-phosphate isomerase similar to Entamoeba and ciliates%3B catalyzes the reaction D-glucosamine 6-phosphate %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E D-fructose 6-phosphate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr4	4164497	4166135	+	DDB_G0286197	DDB_G0286197	contains an N-terminal signal sequence
chr4	4166229	4167686	-	DDB_G0286199	tfb1m	putative rRNA adenosine dimethyltransferase
chr4	4168246	4169290	+	DDB_G0286201	DDB_G0286201_ps	putative pseudogene%3B similar to a Dictyostelid family of oxidoreductases%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0277497%22%3Eaco%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0286203%22%3EDDB_G0286203%3C%2Fa%3E%2C and %3Ca href%3D%22%2Fgene%2FDDB_G0283291%22%3E DDB_G0283291%3C%2Fa%3E
chr4	4169821	4170846	+	DDB_G0286203	DDB_G0286203	NA
chr4	4171531	4172378	+	DDB_G0286325	DDB_G0286325_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0286203%22%3EDDB_G0286203%3C%2Fa%3E
chr4	4173358	4175148	+	DDB_G0286205	DDB_G0286205	NA
chr4	4175501	4176466	+	DDB_G0286327	DDB_G0286327	NA
chr4	4176726	4178160	+	DDB_G0286207	DDB_G0286207	NA
chr4	4178618	4181976	+	DDB_G0286209	DDB_G0286209	NA
chr4	4182511	4185732	+	DDB_G0286329	DDB_G0286329	NA
chr4	4186251	4189457	+	DDB_G0286317	DDB_G0286317	NA
chr4	4189884	4193172	+	DDB_G0286211	DDB_G0286211	NA
chr4	4193633	4194541	+	DDB_G0286213	DDB_G0286213_ps	putative pseudogene%3B similar to a family of %3Ci%3ED. discoideum%3C%2Fi%3E genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0286211%22%3EDDB_G0286211%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0286317%22%3EDDB_G0286317%3C%2Fa%3E
chr4	4194622	4195104	-	DDB_G0286215	DDB_G0286215_ps	putative pseudogene%3B fragment%2C very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0279093%22%3E DDB_G0279093%3C%2Fa%3E%2C a kelch protein that contains also the BTB%2FPOZ domain
chr4	4195341	4197221	+	DDB_G0286217	DDB_G0286217_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0286211%22%3EDDB_G0286211%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0286317%22%3EDDB_G0286317%3C%2Fa%3E
chr4	4198019	4204183	+	DDB_G0286219	DDB_G0286219	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog%3B highly similar to mammalian TBP-associated factor 172 (TAF-172%2FBTAF1) and yeast MOT1
chr4	4205671	4208439	+	DDB_G0286331	DDB_G0286331	NA
chr4	4208827	4210129	-	DDB_G0286221	pigC	putative glycosyltransferase involved in GPI biosynthesis%3B subunit of the transferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-N-acetylglucosamine to phosphatidylinositol (PI)
chr4	4210540	4213036	+	DDB_G0286223	DDB_G0286223	contains up to 13 WD40 repeats%3B very similar to D. purpureum protein
chr4	4213306	4213698	-	DDB_G0286225	DDB_G0286225	similar to D. purpureum protein%3B contains an N-terminal signal sequence
chr4	4214477	4215805	-	DDB_G0286227	DDB_G0286227	similar to D. purpureum protein
chr4	4217038	4217552	+	DDB_G0286189	sumo	sumoylates the MAP kinase kinase Mek1 (mekA)%3B sumoylation is involved in cellular translocation after cAMP stimulation and activation of the kinase
chr4	4218365	4220358	+	DDB_G0286229	alyL	amoeba lysozyme family protein (aly)%2C but divergent compared to %3Ci%3EalyA-D%3C%2Fi%3E
chr4	4221429	4221852	+	DDB_G0286231	DDB_G0286231	NA
chr4	4222260	4225138	-	DDB_G0286233	anapc6	putative ortholog of cdc16%2C a conserved protein containing several TPRs (tetratrico peptide repeats)
chr4	4227524	4229064	+	DDB_G0286185	gpaE	subunit of the heterotrimeric G protein that has GTPase activity%3B involved in the chemotactic response to folate
chr4	4229393	4230570	-	DDB_G0286235	DDB_G0286235	NA
chr4	4231345	4233615	+	DDB_G0286237	DDB_G0286237	NA
chr4	4234344	4235648	+	DDB_G0286239	DDB_G0286239	NA
chr4	4236868	4238190	+	DDB_G0286241	aifD	similar to H. sapiens AIFM2%2C a caspase-independent mitochondrial effector of apoptotic cell death
chr4	4239634	4242645	+	DDB_G0286243	DDB_G0286243	NA
chr4	4243076	4244413	+	DDB_G0286245	DDB_G0286245	NA
chr4	4244481	4244918	-	DDB_G0286247	ponB	protein structurally similar to ponticulin (ponA)%2C a protein that anchors the actin cytoskeleton to the plasma membrane%3B expressed in bacterially grown vegetative and fusion-competent cells
chr4	4245484	4246608	-	DDB_G0286249	DDB_G0286249	NA
chr4	4247436	4249500	+	DDB_G0286333	DDB_G0286333	NA
chr4	4250107	4251736	+	DDB_G0286335	bkdA	catalyzes the reaction 3-methyl-2-oxobutanoate %2B lipoamide %3D S-(2-methylpropanoyl)-dihydrolipoamide %2B CO%3Csub%3E2%3C%2Fsub%3E%3B E1 component of branched-chain keto acid dehydrogenase
chr4	4252375	4254133	+	DDB_G0286251	dnajc3	DnaJ (Hsp40) homolog%2C subfamily C%2C member 3%2C which in H. sapiens is a interferon-induced%2C double-stranded RNA-activated protein kinase inhibitor
chr4	4254280	4255550	-	DDB_G0286253	ttc4	NA
chr4	4255797	4256119	-	DDB_G0286255	DDB_G0286255_ps	putative pseudogene%3B very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268836%22%3EDDB_G0268836%3C%2Fa%3E
chr4	4256396	4258939	-	DDB_G0286257	argC	contains both N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutamate kinase activities%3B catalyzes the reactions N-acetyl-L-glutamate 5-semialdehyde %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %2B phosphate %3D N-acetyl-L-glutamyl 5-phosphate %2B NADPH %2B H%3Csup%3E%2B%3C%2Fsup%3E %3Cb%3Eand%3C%2Fb%3E ATP %2B N-acetyl-L-glutamate %3D ADP %2B N-acetyl-L-glutamate 5-phosphate
chr4	4259863	4260514	+	DDB_G0286259	DDB_G0286259	protein conserved in bacteria and plants%3B D. discoideum contains a second highly similar protein (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0291261%22%3EDDB_G0291261%3C%2Fa%3E)
chr4	4260842	4262107	+	DDB_G0286261	DDB_G0286261	NA
chr4	4262351	4264126	+	DDB_G0286263	DDB_G0286263	NA
chr4	4264645	4265378	+	DDB_G0286265	DDB_G0286265	NA
chr4	4265901	4266640	+	DDB_G0286267	DDB_G0286267	NA
chr4	4267268	4270757	-	DDB_G0286269	DDB_G0286269	contains a putative signal peptide and a C-terminal transmembrane domain
chr4	4271583	4273892	+	DDB_G0286271	DDB_G0286271	NA
chr4	4278216	4278708	-	DDB_G0286187	proB	G-actin binding protein%2C very similar to proA%3B involved in F-actin regulation%2C cytokinesis and development
chr4	4282916	4284908	+	DDB_G0286277	DDB_G0286277	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages
chr4	4285901	4287138	+	DDB_G0286341	DDB_G0286341	highly similar to bacterial glutathione S-transferase%3B catalyzes the reaction RX %2B glutathione %3C%3D%3E HX %2B R-S-glutathione
chr4	4287649	4292809	-	DDB_G0286279	DDB_G0286279	NA
chr4	4293465	4294775	-	DDB_G0286281	DDB_G0286281	NA
chr4	4294974	4296647	-	DDB_G0286321	DDB_G0286321	CAZy family GH9%3B catalyzes the hydrolysis of glucosidic linkages
chr4	4297454	4298377	+	DDB_G0286283	DDB_G0286283	NA
chr4	4298472	4298702	-	DDB_G0286285	DDB_G0286285	NA
chr4	4298931	4300223	-	DDB_G0286287	DDB_G0286287	NA
chr4	4300974	4303039	+	DDB_G0286289	DDB_G0286289	NA
chr4	4303510	4305817	+	DDB_G0286183	agps	catalyses the reaction: 1-acyl-glycerone 3-phosphate %2B a long-chain alcohol %3D 1-alkyl-glycerone 3-phosphate %2B a long-chain acid anion in ether lipid biosynthesis%3B mutations in the human ortholog%2C AGPS%2C causes peroxisomal disorders
chr4	4305951	4306598	-	DDB_G0286291	DDB_G0286291	NA
chr4	4307439	4315737	-	DDB_G0286293	dnajc13	very similar to the mammalian DnaJ homolog subfamily C member 13%2C required in D. melanogaster (Rme-8) for receptor-mediated endocytosis 8
chr4	4316449	4316924	+	DDB_G0286343	DDB_G0286343	NA
chr4	4317522	4320818	+	DDB_G0286295	DDB_G0286295	NA
chr4	4321108	4321704	-	DDB_G0286191	atg8	Dictyostelium homolog of yeast atg8
chr4	4322636	4323120	-	DDB_G0286297	DDB_G0286297	ortholog of human splicing factor 3B 14 kDa subunit (SF3B14) involved in pre-mRNA branch site binding
chr4	4324089	4325444	+	DDB_G0286299	DDB_G0286299	lysin-rich%2C threonine-rich%2C repetitive protein sequence
chr4	4326009	4327169	+	DDB_G0286301	crlE	similar to serpentine%2FG-protein coupled receptors%3B contains 7 putative transmembrane domains
chr4	4327628	4329068	+	DDB_G0286345	zntB	ZIP family zinc transporter%2C LZT subfamily member%3B contains 7 transmembrane domains%3B expressed in pstAB cells
chr4	4329334	4331844	+	DDB_G0286303	ku80	part of the heterodimer ku70%2Fku80 complex%2C which binds to DNA double-strand break ends%3B  involved in double-strand break repair via nonhomologous end joining (NHEJ)
chr4	4332234	4333250	-	DDB_G0286305	DDB_G0286305	expressed in prespore cells
chr4	4334492	4335187	+	DDB_G0286307	DDB_G0286307	contains a putative signal sequence
chr4	4335795	4336934	+	DDB_G0286309	DDB_G0286309	NA
chr4	4337464	4342099	+	DDB_G0286311	DDB_G0286311	similar to comF
chr4	4342189	4343063	-	DDB_G0286313	DDB_G0286313	NA
chr4	4343761	4345981	+	DDB_G0286315	DDB_G0286315	conserved protein%3B contains a signal peptide and 11 transmembrane domains
chr4	4346922	4348214	+	DDB_G0286347	DDB_G0286347	NA
chr4	4348548	4352984	+	DDB_G0286323	DDB_G0286323	NA
chr4	4355028	4356796	+	DDB_G0286353	erkA	NA
chr4	4357070	4358722	-	DDB_G0286361	DDB_G0286361	NA
chr4	4359667	4361014	+	DDB_G0286363	DDB_G0286363	NA
chr4	4361252	4364053	+	DDB_G0286365	DDB_G0286365	NA
chr4	4364169	4365770	-	DDB_G0286367	DDB_G0286367	NA
chr4	4366711	4369185	-	DDB_G0286369	DDB_G0286369	NA
chr4	4370399	4371121	-	DDB_G0286371	cbpM	putative Ca2%2B-binding protein with 4 putative EF-hands%3B belongs to the frequenins%2C a family of myristoyl-switch calcium-binding proteins
chr4	4372108	4373203	+	DDB_G0286373	DDB_G0286373	NA
chr4	4373322	4378505	-	DDB_G0286459	DDB_G0286459	contains one C1 domain (protein kinase C conserved region 1) which is involved in phorbol ester%2Fdiacylglycerol binding%3B contains one coiled-coil domain
chr4	4380273	4380590	+	DDB_G0286463	DDB_G0286463	NA
chr4	4381593	4383490	+	DDB_G0286375	DDB_G0286375	NA
chr4	4383620	4385776	-	DDB_G0286377	DDB_G0286377	NA
chr4	4386579	4387703	+	DDB_G0286379	DDB_G0286379	NA
chr4	4388115	4389608	-	DDB_G0286381	DDB_G0286381	NA
chr4	4391636	4392590	+	DDB_G0286383	DDB_G0286383	NA
chr4	4393013	4394179	+	DDB_G0286385	padA	involved in development and cell differentiation%3B modulates the expression of extracellular cAMP relay genes during aggregation
chr4	4394653	4396384	-	DDB_G0286387	DDB_G0286387	NA
chr4	4400738	4401424	-	DDB_G0286389	rpl34	protein component of the large (60S) ribosomal subunit
chr4	4401925	4403287	+	DDB_G0286391	jcdC	NA
chr4	4403606	4404448	-	DDB_G0286393	DDB_G0286393	the C-terminal half is similar to a D. purpureum protein
chr4	4405482	4407497	+	DDB_G0286395	u2af2	large subunit of the U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) which is a splicing factor that forms a heterodimer with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285077%22%3E%3Ci%3Eu2af1%3C%2Fi%3E%3C%2Fa%3E
chr4	4407676	4409032	-	DDB_G0286397	DDB_G0286397	NA
chr4	4409316	4410466	+	DDB_G0286399	tsfm	NA
chr4	4410583	4412008	-	DDB_G0286401	DDB_G0286401	contains 4 transmembrane proteins
chr4	4412389	4414128	+	DDB_G0286357	rcbA	NA
chr4	4414331	4418910	-	DDB_G0286403	smc4	functions in chromosome dynamics%3B heterodimerizes with smc2
chr4	4419066	4420031	-	DDB_G0286405	DDB_G0286405	NA
chr4	4420447	4424112	+	DDB_G0286465	DDB_G0286465	NA
chr4	4424245	4425105	+	DDB_G0286407	DDB_G0286407_ps	putative pseudogene%3B similar to family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0286437%22%3EDDB_G0286437%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0307042%22%3EDDB_G0307042%3C%2Fa%3E
chr4	4425235	4426170	+	DDB_G0286409	DDB_G0286409	NA
chr4	4426368	4429367	-	DDB_G0286411	bzpN	NA
chr4	4434479	4438712	+	DDB_G0286467	DDB_G0286467	NA
chr4	4443400	4444466	+	DDB_G0286413	DDB_G0286413	NA
chr4	4444849	4444936	-	DDB_G0295603	sno8	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr4	4446182	4449348	+	DDB_G0286455	nxf	nxf %3D %3Cb%3EN%3C%2Fb%3Euclear RNA e%3Cb%3EX%3C%2Fb%3Eport %3Cb%3EF%3C%2Fb%3Eactor
chr4	4451077	4457427	+	DDB_G0286355	mhcA	myosin II heavy chain%2C component of the actin-based molecular motor (conventional myosin)%3B has actin-activated ATPase activity%3B myosin II consists of two heavy chains and one essential (mlcE) and one regulatory light chain (mlcR)%2C respectively
chr4	4458209	4461981	-	DDB_G0286417	DDB_G0286417	NA
chr4	4462466	4463679	-	DDB_G0286457	strap	ortholog of the serine-threonine kinase receptor-associated protein STRAP%2C an inhibitor of TGF-beta signaling%3B contains 7 WD40 repeats
chr4	4464134	4465960	-	DDB_G0286419	cyp519E1	NA
chr4	4466916	4468184	-	DDB_G0286469	DDB_G0286469	NA
chr4	4468376	4468722	+	DDB_G0286421	DDB_G0286421	NA
chr4	4468953	4470715	-	DDB_G0286423	DDB_G0286423	NA
chr4	4471381	4473498	+	DDB_G0286425	srrm1	very similar to the mammalian serine%2Farginine repetitive matrix protein 1 (SRRM1)%2C which is part of pre- and post-splicing multiprotein mRNP complexes involved in numerous pre-mRNA processing events
chr4	4473628	4474491	-	DDB_G0286427	uox	catalyzes the reaction urate %2B O%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E 5-hydroxyisourate %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr4	4476218	4478255	+	DDB_G0286359	svkA	similar ST25 kinase (SOK1) and other STE20-like kinases%3B belongs to the hippo related kinases%3B stress-responsive kinase%3B phosphorylates severin%3B essential for cell separation during cytokinesis
chr4	4478853	4479988	+	DDB_G0286429	DDB_G0286429	NA
chr4	4480269	4482353	-	DDB_G0286431	DDB_G0286431	contains a predicted signal peptide%3B conserved in Dictyostelium
chr4	4482591	4486110	-	DDB_G0286435	DDB_G0286435_ps	putative pseudogene%3B similar to upstream EGF-like domain-containing proteins
chr4	4487639	4491348	-	DDB_G0307043	DDB_G0307043	NA
chr4	4491401	4494850	-	DDB_G0307042	DDB_G0307042	NA
chr4	4495367	4498779	-	DDB_G0286437	DDB_G0286437	NA
chr4	4502152	4502438	+	DDB_G0286439	DDB_G0286439	NA
chr4	4502996	4503699	-	DDB_G0286473	pfdn3	component of the prefoldin complex responsible for targeting proteins to cytosolic chaperonin CCT
chr4	4504352	4504591	-	DDB_G0286475	DDB_G0286475	NA
chr4	4505969	4506214	+	DDB_G0286477	DDB_G0286477	NA
chr4	4506469	4510076	-	DDB_G0286479	DDB_G0286479	NA
chr4	4511137	4512885	-	DDB_G0286441	DDB_G0286441	NA
chr4	4513273	4513947	-	DDB_G0286443	DDB_G0286443	NA
chr4	4514745	4516770	-	DDB_G0286481	DDB_G0286481	putative protein serine%2Fthreonine kinase%3B similar to casein kinase II%2C the alpha chain of a ubiquitious serine%2Fthreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to casein
chr4	4518430	4519368	+	DDB_G0286445	DDB_G0286445	NA
chr4	4520436	4522001	-	DDB_G0286447	DDB_G0286447	similar to the cudA transcriptional regulator
chr4	4523376	4526125	-	DDB_G0286449	DDB_G0286449	NA
chr4	4526380	4528203	-	DDB_G0286351	DDB_G0286351	similar to the cudA transcriptional regulator%3B  REMI mutant forms aberrant fruiting bodies (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0286351%22%3Ecommunity annotation%3C%2Fa%3E) 
chr4	4536016	4537272	+	DDB_G0295785	DDB_G0295785	NA
chr4	4538199	4538839	-	DDB_G0295783	DDB_G0295783	NA
chr4	4542261	4543476	-	DDB_G0295781	DDB_G0295781	weakly similar to S. cerevisiae DUG3%2C involved in degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase
chr4	4544537	4545405	-	DDB_G0295787	hbx11	NA
chr4	4549634	4549789	-	DDB_G0286493	DDB_G0286493	NA
chr4	4551311	4552764	+	DDB_G0286485	DDB_G0286485	NA
chr4	4553269	4555238	-	DDB_G0286487	DDB_G0286487	conserved protein%3B ortholog of mammalian GPR108%3B contains a signal peptide and 7 transmembrane domains
chr4	4555858	4556528	-	DDB_G0286495	itpa	ortholog of human ITPA and S. cerevisiae HAM1%3B hydrolyzes ITP and dITP to their respective monophosphate derivatives%3B defects in human ITPA cause inosine triphosphate pyrophosphohydrolase deficiency characterized by an abnormal accumulation of inosine triphosphate in erythrocytes%2C however pathological symptoms are not known
chr4	4557644	4559815	+	DDB_G0286489	DDB_G0286489	NA
chr4	4560350	4563334	+	DDB_G0286491	clcE	CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles%3B they assemble to form homo-dimers
chr4	4563823	4564182	-	DDB_G0286497	DDB_G0286497_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	4566580	4568219	+	DDB_G0286503	DDB_G0286503_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr4	4569135	4569875	-	DDB_G0286499	pspG	NA
chr4	4570772	4572175	+	DDB_G0286505	DDB_G0286505	conserved protein
chr4	4572284	4574182	-	DDB_G0286507	DDB_G0286507	contains an RNA recognition motif (RRM)%2C a putative RNA binding domain%2C and a thioesterase domain
chr4	4575107	4575571	+	DDB_G0286509	H2Bv3	NA
chr4	4575968	4576885	-	DDB_G0286511	DDB_G0286511	similar to human ubiquitin-conjugating enzyme E2%2C J2 (UBE2J2) and yeast ubiquitin-conjugating 6 (UBC6)
chr4	4577203	4578885	+	DDB_G0286513	DDB_G0286513	NA
chr4	4579041	4582076	-	DDB_G0286515	DDB_G0286515	contains one B-box zinc finger domain and one beta-propeller domain
chr4	4584316	4586258	+	DDB_G0286517	mlysS	catalyzes the reaction ATP %2B L-lysine %2B tRNALys %3D AMP %2B diphosphate %2B L-lysyl-tRNALys
chr4	4586343	4587173	-	DDB_G0286519	dgtB	CAZy family GT2%3B catalytic subunit%2C forms a complex with DPM1 and DPM2%3B catalyzes the reaction GDP-mannose %2B dolichyl phosphate %3C%3D%3E GDP %2B dolichyl D-mannosyl phosphate
chr4	4587626	4588190	-	DDB_G0286521	rpc9	component of the RNA polymerase III complex
chr4	4588407	4590411	+	DDB_G0286523	DDB_G0286523	NA
chr4	4590677	4591594	-	DDB_G0286501	rplP0	NA
chr4	4592587	4593761	+	DDB_G0286525	acmsd	catalyzes the reaction: 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate %3D 2-aminomuconate semialdehyde %2B CO2
chr4	4594246	4595140	-	DDB_G0286527	DDB_G0286527_ps	putative pseudogene%3B similar to a Dictyostelid family of putative SAM-dependent methyltransferases%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0284401%22%3E DDB_G0284401%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0281055%22%3E DDB_G0281055 %3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0281053%22%3E DDB_G0281053%3C%2Fa%3E
chr4	4596405	4597722	-	DDB_G0286531	DDB_G0286531_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr4	4598294	4598367	+	DDB_G0295189	tRNA-Phe-GAA-12	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr4	4603487	4604368	+	DDB_G0294589	DDB_G0294589	NA
chr4	4607142	4609511	+	DDB_G0286533	DDB_G0286533	NA
chr4	4609676	4610629	-	DDB_G0286535	gghA	catalyses the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates
chr4	4611232	4615491	+	DDB_G0286543	DDB_G0286543	contains a RUN domain%2C which is predicted to play a role in Ras-like GTPase signaling pathways
chr4	4616198	4630066	-	DDB_G0286545	vps13D	weakly similar to S. cerevisiae VPS13%2C involved in vacuolar protein sorting and protein-Golgi retention
chr4	4631120	4632211	-	DDB_G0286537	DDB_G0286537	NA
chr4	4632777	4635500	+	DDB_G0286539	DDB_G0286539	has limited similarity to mammalian p53 binding protein 1 (e.g. human TP53BP1)%2C which plays a role in the response to DNA damage%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0286539 is similar (first blast hit%2C both ways) to metazoan p53 binding protein. The homology is mostly within the BRCT domain%2C but several additional small islands of homology are recognized by Blast2Sequences%2C scattered along most of the length of the molecules. p53 binding protein%2C aka 53BP1%2C is thought to mediate between sensors of double strand breaks and effectors of repair processes%2C cell cycle arrest and apoptosis (see Fitzgerald et al%2C Biochemical Society Transactions 37%2C 897-904 (2009).%3Cbr%3E The Dicty gene is overexpressed fourfold (p%3C2e-17)in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted. Most genes whose products have roles in cell cycle progression are overexpressed in this strain%3B this includes a number of genes for replication-coupled DNA repair (Doquang et al%2C in preparation)%2C and more specifically five other genes with putative functions in double-strand break repair (mre11%2C xrcc4%2C lig4%2C PNKP%2C DDB_G0293866%2C DDB_G0286539). The overexpression factors all lie between 3 and 7. The developmental time course of DDB_G0286539 expression (courtesy of dictyExpress-mRNA seq) is similar to that of many DNA repair genes. This suggests that DDB_G0286539 has functions similar to those of 53BP1 in metazoans.%3Cbr%3E No p53 gene has been identified in Dicty. It appears%2C however%2C that at least some aspects of p53-downstream pathways are conserved in amebae. There are a number of rblA-regulated genes without recognizable homology%2C but with %22repair%22-type developmental time courses%2C so the existence of a diverged p53-like molecule is not excluded. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E
chr4	4635713	4636207	-	DDB_G0286541	timm23	mediates the transport of presequence-containing proteins across and into the inner membrane
chr4	4637483	4639599	-	DDB_G0286547	DDB_G0286547_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	4639700	4641171	-	DDB_G0286823	DDB_G0286823_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr4	4641695	4642354	+	DDB_G0286565	DDB_G0286565	NA
chr4	4642679	4644526	+	DDB_G0286567	DDB_G0286567	NA
chr4	4644643	4644987	-	DDB_G0286569	DDB_G0286569	NA
chr4	4645438	4645722	+	DDB_G0286571	DDB_G0286571	NA
chr4	4646321	4647014	+	DDB_G0286573	ponH	structurally similar to ponticulins%3B contains a putative signal peptide
chr4	4647468	4648340	+	DDB_G0286575	DDB_G0286575	similar to retinol dehydrogenase and eukaryotic proteins of the short chain dehydrogenases%2Freductases family
chr4	4648951	4649433	+	DDB_G0286577	DDB_G0286577	NA
chr4	4649529	4651430	-	DDB_G0286579	dnaja5	conserved eukaryotic protein of unknown function%3B contains DNAJ domain and two  C2H2-like Zinc finger domains
chr4	4651768	4652761	+	DDB_G0286581	DDB_G0286581	NA
chr4	4653100	4655469	+	DDB_G0286583	DDB_G0286583	NA
chr4	4655553	4656861	-	DDB_G0286787	DDB_G0286787	NA
chr4	4657116	4657529	+	DDB_G0286585	DDB_G0286585	NA
chr4	4659532	4659945	+	DDB_G0286587	DDB_G0286587	NA
chr4	4660931	4661358	+	DDB_G0286775	DDB_G0286775_ps	putative pseudogene%3B fragment%2C similar to gene %3Ca href%3D%22%2Fgene%2FDDB_G0286791%22%3EDDB_G0286791%3C%2Fa%3E
chr4	4662033	4667190	+	DDB_G0286789	DDB_G0286789	NA
chr4	4668476	4669993	+	DDB_G0286791	DDB_G0286791	NA
chr4	4670086	4670910	-	DDB_G0286589	DDB_G0286589	NA
chr4	4671665	4672491	+	DDB_G0286793	DDB_G0286793	contains 4 putative transmembrane domains
chr4	4672737	4675106	-	DDB_G0286591	DDB_G0286591	NA
chr4	4675755	4677179	+	DDB_G0286593	DDB_G0286593	has similarity to some bacterial and protozoan proteins
chr4	4677268	4679169	-	DDB_G0286595	DDB_G0286595	NA
chr4	4679470	4680028	+	DDB_G0286597	DDB_G0286597	NA
chr4	4682789	4682884	-	DDB_G0295207	tRNA-Ala-UGC-7	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr4	4684750	4686825	-	DDB_G0286795	DDB_G0286795	conserved Dictyostelium protein
chr4	4687512	4688323	-	DDB_G0286601	DDB_G0286601	NA
chr4	4689118	4691291	-	DDB_G0286603	DDB_G0286603	catalyzes the reaction L-glutamine %2B D-fructose 6-phosphate %3C%3D%3E L-glutamate %2B D-glucosamine 6-phosphate
chr4	4692759	4695030	-	DDB_G0286555	racA	RhoBTB subfamily protein%2C which have a unique domain architecture%2C composed of a N-terminal GTPase domain%2C two bric a brac domains (BTB%2C and a conserved C-terminal domain%3B there are orthoolgs in several eukaryotes including mammals%2C but are absent from fungi and plants%3B in Dictyostelium%2C appears to be involved in the regulation of the actin cytoskeleton
chr4	4695789	4696839	-	DDB_G0286605	DDB_G0286605	belongs to the NADP_Rossman superfamily%3B similar to human NMRAL1%3B A. nidulans nmrA is a transcriptional regulator involved in nitrogen metabolite repression
chr4	4697072	4699136	-	DDB_G0286607	fslP	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%3B predicted to have 7 transmembrane domains
chr4	4699815	4701833	-	DDB_G0286609	fslQ	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%3B predicted to have 7 transmembrane domains
chr4	4703129	4704275	-	DDB_G0295671	DDB_G0295671	NA
chr4	4704484	4708242	-	DDB_G0286611	DDB_G0286611	contains at least 9 transmembrane domains
chr4	4708744	4716594	-	DDB_G0286613	DDB_G0286613	NA
chr4	4717096	4718707	-	DDB_G0286797	tsg101	component of the ESCRT-I complex (endosomal sorting complex required for transport)
chr4	4720383	4720657	-	DDB_G0286799	DDB_G0286799	NA
chr4	4721350	4721912	-	DDB_G0286615	DDB_G0286615	NA
chr4	4722525	4724281	-	DDB_G0286617	cycK	similar to metazoan cyclin K%3B predicted to interact with the cyclin-dependent kinase %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0273207%22%3E%3Ci%3Ecdk9%3C%2Fi%3E%3C%2Fa%3E to stimulate CTD (RNA pol II C-Terminal Domain) kinase activity
chr4	4725803	4727293	+	DDB_G0286563	sigM	regulated by the MADS-box transcription factor SrfA during development%3B contains two EGF domains
chr4	4727396	4728781	-	DDB_G0286619	DDB_G0286619	NA
chr4	4729555	4732791	+	DDB_G0286621	fncJ	ortholog of Fanconi anaemia complementation group protein%2C involved DNA cross-link repair%3B also known as BRIP1 (BRCA1 Interacting Protein 1)%2C however the Dicty gene appears to be missing the region that interacts with BRCA1 in the human protein%3B unlike other members of the complex%2C null mutant is not sensitive to DNA damaging agents %3Cbr%2F%3E%3Cbr%2F%3E  mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A%2C B%2C C%2C E%2C F%2C G%2C L and M%3B  the FA complex interacts with ube2t%2C a E2 ubiquitin-conjugating enzyme%2C to monoubiquitinate  FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the  FANCJ helicase as well as FANCN and FANCD1%3B in human%2C mutations in this gene cause Fanconi anaemia%2C an autosomal recessive disorder affecting all bone marrow elements%3B Dictyostelium has orthologs for %3Ca href%3D%22%2Fgene%2FDDB_G0268216%22%3EFANCD2%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0279669%22%3EFANCE%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0292744%22%3EFANCL%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0293476%22%3EFANCI%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0286621%22%3EFANCJ%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274841%22%3EFANCM%3C%2Fa%3E and   %3Ca href%3D%22%2Fgene%2FDDB_G0291199%22%3EUbe2t%3C%2Fa%3E.   
chr4	4733206	4733487	+	DDB_G0286801	DDB_G0286801	NA
chr4	4733890	4735609	-	DDB_G0286557	pten	NA
chr4	4738365	4741726	-	DDB_G0286803	vps41	putative ortholog of VPS41
chr4	4742371	4745221	-	DDB_G0286805	DDB_G0286805	NA
chr4	4745862	4748971	+	DDB_G0286623	mcm2	similar to MCM2%2C a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
chr4	4749168	4750834	-	DDB_G0286625	DDB_G0286625	conserved hyphothetical protein%3B similar to AprA%2C an autocrine repressor of proliferation
chr4	4751624	4753690	-	DDB_G0286807	DDB_G0286807	NA
chr4	4754201	4755574	-	DDB_G0286551	gerE	contains numerous TETP repeats%3B expressed specifically in spores
chr4	4756048	4758163	-	DDB_G0286627	DDB_G0286627	putative protein serine%2Fthreonine kinase%3B belongs to the STE group%3B the kinase domain is similar to yeast BCK1%2C a mitogen-activated protein (MAP) kinase kinase kinase
chr4	4758841	4759279	+	DDB_G0286629	DDB_G0286629	NA
chr4	4759468	4759983	-	DDB_G0286631	ponF	structurally similar to ponticulins%3B contains a putative signal peptide
chr4	4760652	4764568	+	DDB_G0286633	ints4	ortholog of integrator complex subunit 4%2C component of a multiprotein mediator of small nuclear RNA processing
chr4	4764695	4764950	-	DDB_G0286635	DDB_G0286635	NA
chr4	4765267	4767768	-	DDB_G0286637	DDB_G0286637	bifunctional enzyme%3B catalyzes the reactions 5%2C10-methylenetetrahydrofolate %2B 3-methyl-2-oxobutanoate %3C%3D%3E tetrahydrofolate %2B 2-dehydropantoate and (R)-pantoate %2B NADP%2B %3C%3D%3E 2-dehydropantoate %2B NADPH %2B H%2B
chr4	4768925	4770804	-	DDB_G0286809	DDB_G0286809	NA
chr4	4771485	4772787	-	DDB_G0286639	DDB_G0286639	NA
chr4	4773313	4774503	-	DDB_G0286811	DDB_G0286811	NA
chr4	4774707	4775979	+	DDB_G0286641	DDB_G0286641	putative GTPase that has high similarity to NOG1%2FGTPBP4 GTPases%2C which in %3Ci%3ES. cerevisiae%3Ci%3E associates with free 60S ribosomal subunits in the nucleolus%3B this %3Ci%3ED. discoideum%3C%2Fi%3Eprotein is only about half the length and lacks the NOG1 C-terminal domain
chr4	4778203	4780576	+	DDB_G0286643	grlM	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr4	4781245	4784575	+	DDB_G0286645	cstf3	component of the CSTF complex%2C which in mammalian is required for polyadenylation and 3%27-end cleavage of pre-mRNAs
chr4	4784977	4787338	+	DDB_G0286549	flpA	accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr4	4787507	4788407	-	DDB_G0286647	ecmD	forms a 68 kDa heterodimer with ecmB%2C sheathin 55%2C and a homodimer%2C sheathin 53
chr4	4789671	4790625	-	DDB_G0286649	DDB_G0286649	NA
chr4	4791776	4792931	+	DDB_G0286651	aplB	contains three saposin B domains and a putative signal peptide
chr4	4793559	4794032	+	DDB_G0286561	aplC	NA
chr4	4794405	4794959	+	DDB_G0286653	aplO	NA
chr4	4795283	4799675	-	DDB_G0286655	DDB_G0286655	NA
chr4	4800131	4800509	-	DDB_G0286657	DDB_G0286657	contains a predicted signal peptide and two transmembrane domains%3B highly similar to the neighboring gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0286659%22%3E%3Ci%3EDDB_G0286659%3C%2Fi%3E%3C%2Fa%3E
chr4	4800814	4801228	-	DDB_G0286659	DDB_G0286659	contains a predicted signal peptide and two transmembrane domains%3B highly similar to the neighboring gene%2C %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0286657%22%3E%3Ci%3EDDB_G0286657%3C%2Fi%3E%3C%2Fa%3E
chr4	4801886	4803571	+	DDB_G0286661	DDB_G0286661	%3Cb%3ECommunity annotation:%3C%2Fb%3E  DDB G0286661 is weakly similar to the histone chaperone%2C chromatin-assembly factor caf1. DDB G0286661 and another caf1-related gene%2C DDB_G0269800%2C are overexpressed in the Dicty rblA-null (fourfold and sevenfold respectively). Most genes associated with cell cycle progression are overexpressed in this strain. In addition%2C DDB_G0269800 has a PIP (PCNA_interacting) domain (QKKLTSFF)%2C as does human caf1.  These observations support the idea that DDB_G0269800 is actually involved in replication-coupled chromatin assembly.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C September 2009 %3C%2Fi%3E%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ENote:%3C%2Fb%3E Do not confuse this gene with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277827%22%3E%3Ci%3EcafA%3C%2Fi%3E%3C%2Fa%3E%2C calfumirin 1
chr4	4804109	4805424	+	DDB_G0286553	rab21	similar to rab21
chr4	4806034	4806948	-	DDB_G0286663	ecmC	forms a heterodimer%2C sheathin 62%3B also forms a heterotrimer%2C sheathin 68%2C with ecmB and ecmE
chr4	4807662	4811421	-	DDB_G0286665	lin9	putative ortholog of the %3Ci%3EC. elegans%3C%2Fi%3E abnormal cell lineage protein Lin-9%3B the %3Ci%3EDrosophila%3C%2Fi%3E ortholog aly is a member of a multiprotein complex containing retinoblastoma and RbAp48 (the ortholog of Dicty RbbD) which localizes to and stabilizes heterochromatin
chr4	4811831	4812217	+	DDB_G0286813	DDB_G0286813_ps	putative pseudogene%3B fragment%2C similar to large EGF domain-containing proteins%2C such as %3Ca href%3D%22%2Fgene%2FDDB_G0280149%22%3EDDB_G0280149%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0280157%22%3EDDB_G0280157%3C%2Fa%3E
chr4	4812413	4812787	-	DDB_G0286667	DDB_G0286667	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277233%22%3E%3Ci%3EDDB_G0277233%3C%2Fi%3E%3C%2Fa%3E
chr4	4814848	4817084	-	DDB_G0286669	DDB_G0286669	catalyzes the reaction acyl-CoA %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E trans-2%2C3-dehydroacyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr4	4818681	4821260	+	DDB_G0286671	sir2B	N-terminus has several ankyrin repeats%3B C-terminus has a Sirutin (Sir2) domain%2C a NAD-dependent deacetylase that regulates various biological processes by deacetylating histones and other target proteins%3B expressed more highly during development%3B localized to prestalk and rearguard region of the slug%2C and to the apical disc%2C and upper and lower cups in the culminant (similar expression pattern as sir2E) 
chr4	4821852	4825148	+	DDB_G0286673	DDB_G0286673	NA
chr4	4825895	4826186	-	DDB_G0286675	DDB_G0286675	related to the hssA genes
chr4	4826644	4826818	+	DDB_G0286815	DDB_G0286815_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0286673%22%3EDDB_G0286673%3C%2Fa%3E 
chr4	4828905	4833706	-	DDB_G0286559	abcC5	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr4	4835533	4840527	+	DDB_G0286677	DDB_G0286677	NA
chr4	4840734	4841072	-	DDB_G0286679	DDB_G0286679	acyl carrier protein (ACP) is an essential cofactor in the synthesis of fatty acids in bacteria and plants%3B in addition%2C ACP is involved in many other reactions that require acyl transfer steps%2C such as the synthesis of polyketide antibiotics%3B phosphopantetheine is the prosthetic group of ACPs in some multienzyme complexes where it serves as a %27swinging arm%27 for the attachment of activated fatty acid and amino-acid groups
chr4	4841268	4843802	-	DDB_G0286681	DDB_G0286681	NA
chr4	4844157	4844240	+	DDB_G0295191	tRNA-Tyr-GUA-7	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr4	4844701	4845410	+	DDB_G0286683	DDB_G0286683	NA
chr4	4845533	4845826	-	DDB_G0286685	DDB_G0286685	NA
chr4	4846920	4847186	-	DDB_G0286779	DDB_G0286779	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon
chr4	4848740	4848960	-	DDB_G0286687	DDB_G0286687	NA
chr4	4849724	4849992	-	DDB_G0286781	DDB_G0286781	NA
chr4	4852457	4852748	+	DDB_G0286689	DDB_G0286689	 %09related to the hssA genes
chr4	4852997	4853404	+	DDB_G0286691	DDB_G0286691	NA
chr4	4853622	4856076	-	DDB_G0286693	adcD	NA
chr4	4856852	4857664	-	DDB_G0286695	DDB_G0286695	NA
chr4	4858448	4861861	-	DDB_G0286697	DDB_G0286697	NA
chr4	4862450	4863567	+	DDB_G0286699	DDB_G0286699	NA
chr4	4863743	4867280	-	DDB_G0286817	DDB_G0286817	contains 3 RGS (regulator of G protein signalling) domains
chr4	4868445	4870193	+	DDB_G0286701	DDB_G0286701	NA
chr4	4870527	4871540	+	DDB_G0286703	fam18B	similar to a conserved protein of unknown function found associated with the v-SNARE Tlg2p in the membrane of late Golgi vesicles in S. cerevisiae
chr4	4871672	4874662	-	DDB_G0286705	cog7	highly similar to COG7%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits%3B Defects in human COG7 are the cause of congenital disorder of glycosylation type 2E (CDG2E) 
chr4	4875042	4878196	+	DDB_G0286707	DDB_G0286707	NA
chr4	4878583	4879851	-	DDB_G0286709	gpt9	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr4	4880623	4881944	-	DDB_G0286711	gpt8	contains a catalytic domain similar to the lysosomal enzyme GlcNAc-alpha-1-phosphotransferase
chr4	4882439	4883209	-	DDB_G0286713	DDB_G0286713	NA
chr4	4883827	4884270	-	DDB_G0286715	ponC2	similar to ponticulin (ponA)%2C a protein that anchors the actin cytoskeleton to the plasma membrane%3B almost identical to the 4 upstream genes
chr4	4885049	4885492	-	DDB_G0286717	ponC1	similar to ponticulin (ponA)%2C a protein that anchors the actin cytoskeleton to the plasma membrane%3B almost identical to 1 downstream and 3 upstream genes
chr4	4886230	4886673	-	DDB_G0286719	ponC4	similar to ponticulin (ponA)%2C a protein that anchors the actin cytoskeleton to the plasma membrane%3B almost identical to 3 downstream and 1 upstream gene
chr4	4887442	4887885	-	DDB_G0286721	ponC3	similar to ponticulin (ponA)%2C a protein that anchors the actin cytoskeleton to the plasma membrane%3B almost identical to 2 downstream and 2 upstream genes
chr4	4888589	4889032	-	DDB_G0286723	ponC5	similar to ponticulin (ponA)%2C a protein that anchors the actin cytoskeleton to the plasma membrane%3B almost identical to the 4 downstream genes
chr4	4889609	4899939	-	DDB_G0286725	vps13A	putative ortholog of S. cerevisiae VPS13%2C involved in vacuolar protein sorting and protein-Golgi retention
chr4	4900621	4901710	-	DDB_G0286727	DDB_G0286727	similar to ChaC proteins%2C thought to be associated with the putative ChaA calcium%2Fhydrogen cation transport protein in E. coli%2C but with a PUA RNA binding domain fused at the carboxyl terminus
chr4	4902848	4903802	+	DDB_G0286729	DDB_G0286729	NA
chr4	4904757	4905377	+	DDB_G0286731	DDB_G0286731	NA
chr4	4905654	4908357	-	DDB_G0286733	hbx12	NA
chr4	4909097	4911357	+	DDB_G0286735	DDB_G0286735	contains one C3HC4-type (RING) zinc finger and 7 WD40 repeats
chr4	4911744	4913372	+	DDB_G0286737	DDB_G0286737	NA
chr4	4913488	4914188	-	DDB_G0286739	DDB_G0286739	NA
chr4	4914735	4915994	+	DDB_G0286741	DDB_G0286741	NA
chr4	4916138	4917744	-	DDB_G0286743	cyp555A1	NA
chr4	4918278	4920365	+	DDB_G0286821	DDB_G0286821	NA
chr4	4920445	4921982	-	DDB_G0286745	DDB_G0286745	NA
chr4	4922308	4922992	-	DDB_G0286747	H2AZ	component of the H2A-H2B-H3-H4 histone octamer%3B dimerizes with histone H2B
chr4	4924314	4927076	+	DDB_G0286749	DDB_G0286749	NA
chr4	4927372	4927911	-	DDB_G0286751	DDB_G0286751	NA
chr4	4929423	4929718	-	DDB_G0286783	DDB_G0286783	NA
chr4	4930004	4931298	+	DDB_G0286753	eIF5	EIF5 ortholog%2C the eukaryotic initiation factor 5%3B catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex
chr4	4931449	4932181	-	DDB_G0286755	DDB_G0286755	catalyzes the reaction NADPH %2B 7%2C8-dihydrofolate %3C%3D%3E NADP %2B tetrahydrofolate in folate biosynthesis and formylTHF biosynthesis
chr4	4933318	4934654	+	DDB_G0286757	DDB_G0286757	NA
chr4	4935044	4935605	-	DDB_G0286759	DDB_G0286759	similar to the mammalian KRTCAP2 (keratinocytes-associated protein 2)%3B contains 4 putative transmembrane domains
chr4	4936897	4937811	+	DDB_G0286761	DDB_G0286761	NA
chr4	4937865	4939844	-	DDB_G0286763	DDB_G0286763	NA
chr4	4940455	4942254	+	DDB_G0286765	DDB_G0286765	similar to BCS1%2C a mitochondrial chaperone required for assembly of cytochrome BC(1) complex%3B expressed in pstA and pstO cells and in the upper and lower cups during culmination
chr4	4943773	4944222	+	DDB_G0286767	DDB_G0286767	NA
chr4	4945147	4945882	-	DDB_G0286769	DDB_G0286769	NA
chr4	4946624	4951538	-	DDB_G0286773	gflB	similar to son of sevenless%3B contains RhoGAP and RasGEF domains
chr4	4953029	4953725	-	DDB_G0286827	DDB_G0286827_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0280997%22%3EDDB_G0280997%3C%2Fa%3E
chr4	4954349	4955072	+	DDB_G0286829	DDB_G0286829	NA
chr4	4955377	4955700	-	DDB_G0286831	DDB_G0286831	NA
chr4	4956036	4957022	-	DDB_G0286833	DDB_G0286833	NA
chr4	4957742	4959343	+	DDB_G0286835	DDB_G0286835	NA
chr4	4960352	4961950	+	DDB_G0286837	gtaM	has 18 amino acids between the two CX2C motifs
chr4	4963061	4964091	+	DDB_G0286839	gtaW	has 20 amino acids between the two CX2C motifs
chr4	4966020	4967675	-	DDB_G0286841	DDB_G0286841	member of the AGC kinase group%3B similar to the kinase domains of MAST kinases (Microtubule-Associated Serine%2FThreonine kinase)
chr4	4968885	4970116	-	DDB_G0286843	gtaQ	has 19 amino acids between the two CX2C motifs
chr4	4972112	4972996	+	DDB_G0286845	DDB_G0286845	NA
chr4	4973256	4975793	-	DDB_G0286847	DDB_G0286847	NA
chr4	4977120	4977989	-	DDB_G0286849	DDB_G0286849	similar to bacterial short-chain dehydrogenase%2Freductase family proteins%2C and human RDH8 (retinol dehydrogenase 8)
chr4	4978558	4979442	+	DDB_G0286861	DDB_G0286861	NA
chr4	4982216	4985142	-	DDB_G0286851	tgrE1	conserved hypothetical protein%3B contains an IPT%2FTIG domain found in cell surface receptors
chr4	4985657	4988428	+	DDB_G0286825	tgrD1	contains three immunolubulin-like folds (IPT%2FTIG domains)
chr4	4990193	4990906	+	DDB_G0286853	DDB_G0286853	NA
chr4	4992545	4994267	-	DDB_G0286855	gtaD	has 17 amino acids between the two CX2C motifs
chr4	4996053	4996442	-	DDB_G0286857	glod5	conserved protein%2C ortholog of human GLOD5
chr4	4996972	4999916	+	DDB_G0286863	DDB_G0286863_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr4	4999193	4999266	+	DDB_G0295193	tRNA-Phe-GAA-13	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr4	5001179	5001412	-	DDB_G0286865	DDB_G0286865	NA
chr4	5001922	5006849	-	DDB_G0286867	DDB_G0286867	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr4	5007468	5008733	+	DDB_G0286869	DDB_G0286869	NA
chr4	5008976	5009655	+	DDB_G0286871	DDB_G0286871	similar to bacterial and fungal proteins of the GNAT family
chr4	5009906	5011103	+	DDB_G0286873	DDB_G0286873	NA
chr4	5011319	5012971	+	DDB_G0286875	gatA	catalyzes the reaction ATP %2B L-glutamyl-tRNA(Gln) %2B L-glutamine %3D ADP %2B phosphate %2B L-glutaminyl-tRNA(Gln) %2B L-glutamate
chr4	5013005	5017830	-	DDB_G0286877	DDB_G0286877	NA
chr4	5018337	5018897	-	DDB_G0286879	DDB_G0286879	NA
chr4	5019240	5022826	+	DDB_G0286881	DDB_G0286881	NA
chr4	5022922	5023576	-	DDB_G0286883	DDB_G0286883	putative ortholog of E. coli rppH
chr4	5024349	5026256	+	DDB_G0286885	DDB_G0286885	NA
chr4	5026472	5026974	-	DDB_G0286887	DDB_G0286887	NA
chr4	5027996	5030071	-	DDB_G0286889	fut10	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr4	5031762	5035686	+	DDB_G0286891	DDB_G0286891	contains 8 transmembrane domains
chr4	5035700	5036863	-	DDB_G0286893	act29	has 56%25 identity with human beta-actin (SwissProt P60709)
chr4	5037852	5040315	+	DDB_G0286895	grlD	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr4	5040461	5045138	-	DDB_G0286897	DDB_G0286897	similar to comF
chr4	5047177	5047250	-	DDB_G0295205	tRNA-Val-AAC-18	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr4	5047649	5050777	+	DDB_G0286899	DDB_G0286899	NA
chr4	5050966	5053146	-	DDB_G0286901	DDB_G0286901	NA
chr4	5053310	5058130	-	DDB_G0286967	med25	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 25%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr4	5059870	5060410	-	DDB_G0286909	anapc11	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr4	5061049	5062551	+	DDB_G0286911	DDB_G0286911	NA
chr4	5063512	5069942	+	DDB_G0286969	DDB_G0286969	NA
chr4	5070335	5073388	+	DDB_G0286913	DDB_G0286913	NA
chr4	5073666	5073999	-	DDB_G0286915	DDB_G0286915	NA
chr4	5074484	5076486	+	DDB_G0286917	DDB_G0286917	NA
chr4	5076581	5077048	-	DDB_G0286905	pspE	expressed in prespore cells
chr4	5077667	5079750	-	DDB_G0286919	uba2	conserved protein%2C forms a heterodimer with sae1%3B acts as a E1 ligase for sumo
chr4	5081040	5082644	-	DDB_G0286921	DDB_G0286921	NA
chr4	5083931	5084620	-	DDB_G0286907	ubqD	NA
chr4	5085448	5086911	-	DDB_G0286923	DDB_G0286923	NA
chr4	5087989	5089064	+	DDB_G0286925	DDB_G0286925	enriched in prespore cells
chr4	5089206	5089448	-	DDB_G0286927	nedd8l2	similar to the conserved NEDD8 (neddylin) protein%2C however%2C this is the most divergent member of the family in %3Ci%3EDictyostelium%3C%2Fi%3E
chr4	5090123	5090773	+	DDB_G0286929	DDB_G0286929	NA
chr4	5091515	5107567	+	DDB_G0286931	DDB_G0286931	NA
chr4	5107749	5110311	+	DDB_G0286933	DDB_G0286933	NA
chr4	5110525	5113395	+	DDB_G0286963	DDB_G0286963	NA
chr4	5114045	5115649	+	DDB_G0286935	DDB_G0286935	NA
chr4	5117185	5117484	+	DDB_G0286965	DDB_G0286965	NA
chr4	5117554	5117679	+	DDB_G0286937	DDB_G0286937	NA
chr4	5118438	5119358	+	DDB_G0286939	DDB_G0286939	NA
chr4	5119924	5122501	+	DDB_G0286941	DDB_G0286941	NA
chr4	5123987	5124142	+	DDB_G0286943	DDB_G0286943	NA
chr4	5125247	5126362	+	DDB_G0286945	gtr3	distant relative of CAZy family GT8%3B similar to glycogenin and galactinol synthase
chr4	5126978	5131999	+	DDB_G0286947	DDB_G0286947	NA
chr4	5132153	5132583	+	DDB_G0286949	DDB_G0286949	NA
chr4	5132945	5134730	-	DDB_G0286961	rbrA	required for cell type proportioning%3B contains two IBR (In Between Ring fingers) domains
chr4	5136274	5139707	+	DDB_G0286951	DDB_G0286951	NA
chr4	5140537	5141493	+	DDB_G0286953	uduG	upregulated in the uninfected %3Ca href%3D%22%2Fgene%2FDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr4	5142082	5143794	-	DDB_G0286973	DDB_G0286973	NA
chr4	5144135	5145250	-	DDB_G0286975	DDB_G0286975_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0287215%22%3EDDB_G0287215%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0286955%22%3EDDB_G0286955%3C%2Fa%3E
chr4	5145533	5146657	-	DDB_G0286955	DDB_G0286955	NA
chr4	5147352	5147778	-	DDB_G0286957	DDB_G0286957	NA
chr4	5148727	5149869	-	DDB_G0286977	DDB_G0286977	NA
chr4	5150412	5152907	-	DDB_G0286979	DDB_G0286979	NA
chr4	5154310	5156466	-	DDB_G0286959	DDB_G0286959	similar to D. purpureum protein
chr4	5158045	5163167	+	DDB_G0286981	DDB_G0286981	NA
chr4	5163425	5164927	-	DDB_G0286983	DDB_G0286983	NA
chr4	5166703	5168037	-	DDB_G0286987	DDB_G0286987_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr4	5168273	5168355	+	DDB_G0295195	tRNA-Leu-UAA-11	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr4	5169198	5170721	-	DDB_G0286993	DDB_G0286993	NA
chr4	5171363	5174437	-	DDB_G0286985	zipA	NA
chr4	5175729	5176130	+	DDB_G0286989	DDB_G0286989	NA
chr4	5177493	5178949	+	DDB_G0286991	DDB_G0286991	NA
chr4	5179444	5181688	+	DDB_G0286995	DDB_G0286995	NA
chr4	5181860	5183581	+	DDB_G0286999	DDB_G0286999	NA
chr4	5188585	5190825	-	DDB_G0287001	DDB_G0287001	member of the TKL (tyrosine kinase-like) group%3B contains zinc-binding LIM domain
chr4	5191304	5192557	-	DDB_G0287003	DDB_G0287003	contains 10 putative transmembrane domains
chr4	5193960	5195815	+	DDB_G0287005	DDB_G0287005	similar to the H. sapiens eukaryotic translation initiation factor 3%2C subunit M (EIF3M)
chr4	5196102	5197767	+	DDB_G0287007	arpF	ortholog of the conserved actin related protein ARP6%2C in mammalian called ACTR6%2C a putative component of a chromatin-remodeling complex
chr4	5197882	5199603	-	DDB_G0287009	mcfC	putative orthlolog of H. sapiens SLC25A24 calcium-dependent mitochondrial ATP-Mg%2FPi carrier%3B contains four N-terminal EF-hands%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr4	5201277	5202252	-	DDB_G0287021	vps20	component of the ESCRT-III complex (endosomal sorting complex required for transport)%3B putative ortholog of human CHMP6 (Chromatin Modifying Protein 6) and yeast VPS20
chr4	5202818	5203577	+	DDB_G0287023	DDB_G0287023	NA
chr4	5203841	5204952	+	DDB_G0287025	DDB_G0287025	NA
chr4	5205106	5206420	-	DDB_G0287013	DDB_G0287013	NA
chr4	5207077	5207679	+	DDB_G0287015	DDB_G0287015	contains two transmembrane domains
chr4	5207898	5208884	-	DDB_G0287017	DDB_G0287017	belongs to the HAD-like hydrolase superfamily%3B similar to human HDHD3 (haloacid dehalogenase-like hydrolase domain-containing protein 3)
chr4	5209121	5209808	+	DDB_G0287019	med9	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 9%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr4	5209927	5213040	-	DDB_G0287027	DDB_G0287027	NA
chr4	5213175	5214560	-	DDB_G0287105	DDB_G0287105	NA
chr4	5215181	5216371	+	DDB_G0287037	DDB_G0287037	NA
chr4	5216605	5218805	-	DDB_G0287101	noxB	homolog of the mammalian flavocytochrome b large subunit gp91phox%2C essential for spore formation
chr4	5219424	5221022	-	DDB_G0287039	DDB_G0287039	NA
chr4	5221229	5223369	+	DDB_G0287041	DDB_G0287041	NA
chr4	5223614	5224928	-	DDB_G0287107	DDB_G0287107	NA
chr4	5225371	5226538	+	DDB_G0287043	DDB_G0287043	NA
chr4	5226859	5226941	-	DDB_G0295203	tRNA-Leu-UAA-12	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr4	5227447	5227876	-	DDB_G0287047	DDB_G0287047	NA
chr4	5231470	5232536	+	DDB_G0287051	DDB_G0287051	NA
chr4	5232785	5235479	-	DDB_G0287109	athl1	conserved glycoside hydrolase family 65 protein
chr4	5235945	5236851	-	DDB_G0287053	lsm4	member of heteromeric complexes involved in mRNA splicing (lsm2-8) and mRNA degradation (lsm1-7)
chr4	5237174	5250239	-	DDB_G0287055	vps13F	weakly similar to S. cerevisiae VPS13%2C involved in vacuolar protein sorting and protein-Golgi retention
chr4	5251113	5252898	+	DDB_G0287033	nagA	catalyses the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
chr4	5254629	5257005	+	DDB_G0287035	lmpB	NA
chr4	5258336	5261281	-	DDB_G0287057	gtaN	has 18 amino acids between the two CX2C motifs
chr4	5266193	5267157	+	DDB_G0287111	DDB_G0287111	conserved protein
chr4	5267330	5267886	+	DDB_G0304886	DDB_G0304886	NA
chr4	5268402	5272596	+	DDB_G0287103	DDB_G0287103	similar to timeless%2C which in Drosophila forms a complex at replication forks that plays a role in the DNA damage response%2C and is phosphorylated by cyclin-dependent kinases %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation: %3C%2Fb%3EDDB G0287103 is induced 11-fold in a %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-deficient%3C%2Fa%3E strain. Since the vast majority of mitotic and DNA replication genes are overexpressed in these cells%2C this supports a role of DDB G0287103 in Dictyostelium cell cycle progression.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C April 2009 %3C%2Fi%3E  
chr4	5272697	5275219	-	DDB_G0287059	DDB_G0287059	NA
chr4	5275365	5277665	-	DDB_G0287113	DDB_G0287113	NA
chr4	5278698	5284733	+	DDB_G0287061	DDB_G0287061	contains a Rab GTPase domain%2C but due to its predicted molecular weight (1%2C836 amino acids)%2C it is not a small GTPase
chr4	5285069	5286549	+	DDB_G0287063	DDB_G0287063	weakly similar to Polysphondylium pallidum 64 kDa cell surface glycoprotein
chr4	5286829	5287431	+	DDB_G0287065	DDB_G0287065	NA
chr4	5287659	5288891	-	DDB_G0287115	DDB_G0287115	NA
chr4	5289082	5289474	-	DDB_G0287067	DDB_G0287067	NA
chr4	5289970	5291240	+	DDB_G0287069	DDB_G0287069	NA
chr4	5291519	5292739	+	DDB_G0287071	DDB_G0287071	NA
chr4	5293321	5294530	+	DDB_G0287073	DDB_G0287073	contains a single HMG1%2F2 box
chr4	5294660	5296282	-	DDB_G0287075	DDB_G0287075	NA
chr4	5297647	5299535	+	DDB_G0287031	gpaC	subunit of the heterotrimeric G protein that has GTPase activity%3B has N-terminal pleckstrin homology (PH) domain
chr4	5299968	5301629	+	DDB_G0287077	DDB_G0287077	NA
chr4	5302047	5303965	+	DDB_G0287079	DDB_G0287079	ortholog of mammalian cdk5rap1 and bacterial miaB involved in the the thiolation and methylation of tRNA
chr4	5304055	5305096	-	DDB_G0287081	DDB_G0287081	NA
chr4	5305570	5307430	+	DDB_G0287083	DDB_G0287083	NA
chr4	5307684	5308631	-	DDB_G0287085	DDB_G0287085	there is a paralog of this gene%2C %3Ca href%3D%22%2Fgene%2FDDB_G0267610%22%3E
chr4	5309664	5311235	-	DDB_G0287087	cyp513B1	NA
chr4	5311879	5312367	-	DDB_G0287089	DDB_G0287089	NA
chr4	5312947	5313029	+	DDB_G0295197	tRNA-Tyr-GUA-8	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr4	5313189	5313680	-	DDB_G0287091	DDB_G0287091	NA
chr4	5314330	5314800	-	DDB_G0287093	DDB_G0287093	NA
chr4	5315241	5319287	-	DDB_G0287117	DDB_G0287117_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr4	5319738	5327230	-	DDB_G0287119	pks24	putative type I iterative polyketide synthase
chr4	5328050	5328886	-	DDB_G0287121	nat4	NA
chr4	5330551	5337779	+	DDB_G0287095	pks25	putative type I iterative polyketide synthase
chr4	5338338	5339834	+	DDB_G0287097	DDB_G0287097	contains 4 FNIP repeats%3B conserved in Dictyostelium
chr4	5339911	5340579	-	DDB_G0287099	DDB_G0287099	NA
chr4	5341430	5346451	+	DDB_G0287123	DDB_G0287123	NA
chr4	5352426	5353073	-	DDB_G0287129	DDB_G0287129	contains a putative signal peptide
chr4	5353824	5354760	-	DDB_G0287131	gtf2f2	transcription initiation factor TFIIF beta subunit
chr4	5355378	5357627	-	DDB_G0287133	DDB_G0287133	NA
chr4	5359561	5361351	+	DDB_G0287187	DDB_G0287187	NA
chr4	5361475	5362787	-	DDB_G0287135	DDB_G0287135	NA
chr4	5363024	5363750	-	DDB_G0287189	DDB_G0287189	NA
chr4	5366531	5366749	+	DDB_G0287191	DDB_G0287191	NA
chr4	5367030	5367244	-	DDB_G0287137	vatA_ps	putative pseudogene%3B small fragment%2C almost identical with parts of %3Ca href%3D%22%2Fgene%2FDDB_G0287127%22%3EvatA%3C%2Fa%3E%2C the vacuolar ATPase subunit A
chr4	5368411	5370078	+	DDB_G0287139	DDB_G0287139	NA
chr4	5370324	5372643	-	DDB_G0287127	vatA	ortholog of the A subunit of vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B the A subunit is part of the V1 subunit
chr4	5374001	5375464	+	DDB_G0287141	phesA	catalyzes the reaction ATP %2B L-phenylalanine %2B tRNAPhe %3D AMP %2B diphosphate %2B L-phenylalanyl-tRNAPhe%3B in S. cerevisiae%2C acts as a tetramer composed of two alpha and two beta subunits
chr4	5376601	5377009	+	DDB_G0287175	DDB_G0287175_ps	putative pseudogene%3B similar to a D. discoideum gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0295813%22%3EDDB_G0295813%3C%2Fa%3E
chr4	5377683	5378043	-	DDB_G0287145	DDB_G0287145	NA
chr4	5379967	5381914	-	DDB_G0287147	gnl3	similar to the conserved guanine nucleotide-binding protein-like 3%3B also called nucleostemin in mammals%2C a protein in the nucleolus of most stem cells and many tumor cells%3B involved in cell-cycle progression
chr4	5382189	5383827	-	DDB_G0287149	DDB_G0287149	similar to mammalian DNA polymerase kappa (POLK)%2C and E. coli dinB%2C a translesion DNA repair polymerase
chr4	5388100	5391276	+	DDB_G0287193	DDB_G0287193	NA
chr4	5391671	5393263	+	DDB_G0287195	DDB_G0287195	NA
chr4	5393798	5394727	-	DDB_G0287151	DDB_G0287151	similar to retinol dehydrogenase and eukaryotic short chain dehydrogenases%2Freductases family proteins
chr4	5395993	5396806	+	DDB_G0287197	ncbp2	ortholog of mammalian NCPB2 and yeast CBP2%3B small subunit of the heterodimeric cap binding complex involved in mediating U snRNA export from the nucleus
chr4	5397049	5398785	-	DDB_G0287199	5NT	catalyzes the reaction a 5%27-ribonucleotide %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E a ribonucleoside %2B phosphate%3B enriched in prestalk cells
chr4	5400400	5401252	+	DDB_G0287153	DDB_G0287153	similar to H. sapiens UBE2I and S. cerevisiae UBC9
chr4	5401496	5403973	-	DDB_G0287201	DDB_G0287201	NA
chr4	5404659	5405023	-	DDB_G0287203	elof1	ortholog of the conserved elongation factor 1%2C a transcription elongation factor that contains a conserved zinc finger domain%3B implicated in chromatin structure maintenance in actively transcribed regions in S. cerevisiae
chr4	5405589	5405838	-	DDB_G0287205	DDB_G0287205	NA
chr4	5407048	5407542	+	DDB_G0287155	DDB_G0287155	NA
chr4	5407710	5412538	-	DDB_G0287157	trappc11	conserved trafficking protein particle (TRAPP) complex subunit%3B mutations in human TRAPPC11 cause limb-girdle muscular dystrophy 2S
chr4	5412959	5415025	-	DDB_G0287159	cysS	catalyzes the reaction ATP %2B L-cysteine %2B tRNACys %3D AMP %2B diphosphate %2B L-cysteinyl-tRNACys
chr4	5415608	5416731	-	DDB_G0287161	DDB_G0287161	NA
chr4	5417279	5417901	-	DDB_G0287125	proA	G-actin binding protein%2C very similar to proB%3B involved in F-actin regulation%2C cytokinesis and development
chr4	5419077	5419983	-	DDB_G0287163	DDB_G0287163	NA
chr4	5420537	5422504	+	DDB_G0287165	DDB_G0287165	similar to spastin (spastic paraplegia 4 protein)%2C a mammalian ATP-dependent microtubule severing protein
chr4	5422690	5427611	-	DDB_G0287167	DDB_G0287167	NA
chr4	5428138	5429052	-	DDB_G0287169	DDB_G0287169	NA
chr4	5429343	5435050	+	DDB_G0287171	DDB_G0287171	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr4	5435309	5435390	+	DDB_G0295199	tRNA-Leu-AAG-4	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr4	5435936	5436017	+	DDB_G0295201	tRNA-Leu-AAG-5	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr4	5437470	5442645	+	DDB_G0287207	DDB_G0287207	large protein (1%2C685 amino acids) containing a Rab domain%3B Rab small GTPases are usually around 200 amino acids in length
chr4	5444697	5445773	-	DDB_G0287173	DDB_G0287173_ps	putative pseudogene%3B similar to protein kinases but does not contain the consensus sequences required for kinase function
chr4	5445848	5446186	-	DDB_G0287177	DDB_G0287177	NA
chr4	5446279	5446572	-	DDB_G0287179	DDB_G0287179	NA
chr4	5446818	5448043	+	DDB_G0287183	DDB_G0287183_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0272592%22%3EDDB_G0272592%3C%2Fa%3E  and %3Ca href%3D%22%2Fgene%2FDDB_G0293664%22%3EDDB_G0293664%3C%2Fa%3E 
chr4	5448496	5448951	-	DDB_G0287185	DDB_G0287185	contains one ML (MD-2-related lipid recognition) domain%3B similar to fungal proteins of the NPC2 family%3B contains a predicted signal peptide
chr5	101	1635	-	DDB_G0287249	DDB_G0287249_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr5	3070	4182	-	DDB_G0287215	DDB_G0287215	NA
chr5	5282	8716	+	DDB_G0287217	DDB_G0287217	NA
chr5	8994	9773	-	DDB_G0287219	DDB_G0287219	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein similar to bacterial proteins%3B contains a predicted signal peptide
chr5	10149	17304	-	DDB_G0287221	DDB_G0287221	similar to TRIP12 (thyroid hormone receptor interactor 12)%2C a component of PA700%2C an ATP-dependent multisubunit protein that activates the proteolytic activities of the 20S proteasome
chr5	19093	19836	-	DDB_G0287251	DDB_G0287251	NA
chr5	21182	23287	+	DDB_G0287225	DDB_G0287225	NA
chr5	23737	24143	+	DDB_G0287227	trxE	small disulphide-containing redox protein that serves as a general protein disulphide oxidoreductase
chr5	24322	26298	-	DDB_G0287229	chdh	catalyzes the reaction: choline %2B acceptor %3D betaine aldehyde %2B reduced acceptor%3B ortholog of the mammalian CHDH%3B contains a putative signal  sequence
chr5	28270	31440	-	DDB_G0287231	manF	expressed in prespore cells
chr5	32102	32728	-	DDB_G0287233	spoT	NA
chr5	33457	34452	+	DDB_G0287253	gemin2	ortholog of Gemin 2%2FSIP1 (Survival of motor neuron protein-interacting protein 1)%2C a component of Cajal bodies (CBs) and Gems%2C nuclear organelles responsible for spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis
chr5	34540	35400	-	DDB_G0287213	rcdJJ	NA
chr5	35600	38856	-	DDB_G0287235	DDB_G0287235_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289689%22%3EDDB_G0289689%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283787%22%3EDDB_G0283787%3C%2Fa%3E
chr5	40886	40958	+	DDB_G0295233	tRNA-Lys-UUU-16	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr5	41773	42591	+	DDB_G0287211	rab11B	NA
chr5	42818	43808	-	DDB_G0287237	DDB_G0287237_ps	putative pseudogene%2C contains a kinase domain that lacks a RD signature
chr5	44049	47251	-	DDB_G0287255	gcvP	catalyzes the reaction glycine %2B H-protein-lipoyllysine %3C%3D%3E H-protein-S-aminomethyldihydrolipoyllysine %2B CO%3Csub%3E2%3C%2Fsub%3E
chr5	47854	49326	-	DDB_G0287269	ccbl	catalyzes the reaction L-kynurenine %2B 2-oxoglutarate %3C%3D%3E 4-(2-aminophenyl)-2%2C4-dioxobutanoate %2B L-glutamate
chr5	49910	51750	-	DDB_G0287257	DDB_G0287257	NA
chr5	52532	53749	-	DDB_G0287239	DDB_G0287239	NA
chr5	54882	57146	-	DDB_G0287259	cdh1	ortholog of FZR1%2FCDH1%2C that regulates the ubiquitin ligase activity of the anaphase promoting complex%2Fcyclosome (APC%2FC)%2C which directs ubiquitination of cyclins resulting in mitotic exit%3B related to cdc20 
chr5	58745	59872	+	DDB_G0287241	DDB_G0287241	NA
chr5	60363	61526	+	DDB_G0287243	DDB_G0287243	NA
chr5	61689	63845	-	DDB_G0287261	gphn	conserved microtubule-associated protein involved in membrane protein-cytoskeleton interactions%3B implicated in molybdenum cofactor biosynthesis
chr5	64505	64829	+	DDB_G0287263	DDB_G0287263	NA
chr5	65084	67106	-	DDB_G0287265	DDB_G0287265	NA
chr5	67613	69799	-	DDB_G0287267	DDB_G0287267	NA
chr5	72820	74155	+	DDB_G0287273	wdr5	highly similar to WDR5 protein%2C involved in histone H3 K4 methylation
chr5	74321	76791	-	DDB_G0287287	DDB_G0287287	NA
chr5	77605	82107	+	DDB_G0287275	DDB_G0287275	NA
chr5	82214	83227	-	DDB_G0287277	DDB_G0287277	members of the NAD-dependent epimerase%2Fdehydratase family use nucleotide-sugar substrates for a variety of chemical reactions
chr5	83567	83895	-	DDB_G0287279	DDB_G0287279	belongs to the UPF0203 family%3B similar to human TRIAP1 (TP53-regulated inhibitor of apoptosis 1)
chr5	84160	85529	-	DDB_G0287281	DDB_G0287281	catalyzes the condensation of acetyl-CoA and oxaloacetate to citrate
chr5	86247	90903	+	DDB_G0287289	DDB_G0287289	NA
chr5	91412	91564	-	DDB_G0287283	DDB_G0287283	NA
chr5	91906	93854	-	DDB_G0287271	gol	golgi and vesicle associated protein%3B predominantly targeted to the endosomal pathway
chr5	94597	95862	+	DDB_G0287299	DDB_G0287299	NA
chr5	96074	97686	-	DDB_G0287423	DDB_G0287423	contains 12 putative transmembrane domains
chr5	98175	99777	-	DDB_G0287425	DDB_G0287425	NA
chr5	100675	102275	-	DDB_G0346924	DDB_G0346924	NA
chr5	102942	104539	-	DDB_G0346922	DDB_G0346922	NA
chr5	104846	106843	-	DDB_G0287303	DDB_G0287303	amino acid permeases are integral membrane proteins involved in the transport of amino acids into the cell%3B contains 12 putative transmembrane domains
chr5	107640	108752	+	DDB_G0287427	DDB_G0287427	NA
chr5	109242	110242	+	DDB_G0287429	DDB_G0287429	NA
chr5	110292	110834	-	DDB_G0287305	DDB_G0287305	NA
chr5	111192	112022	-	DDB_G0287307	gtf2e2	general transcription factor required for the initiation of transcription by RNA polymerase II
chr5	112586	113185	+	DDB_G0287309	DDB_G0287309	NA
chr5	113384	113869	-	DDB_G0287311	DDB_G0287311_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0283145%22%3EDDB_G0283145%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269484%22%3EDDB_G0269484%3C%2Fa%3E
chr5	114376	116400	+	DDB_G0287313	DDB_G0287313	NA
chr5	117395	118571	-	DDB_G0287431	DDB_G0287431_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0281645%22%3EDDB_G0281645%3C%2Fa%3E
chr5	118782	119003	-	DDB_G0287433	DDB_G0287433	NA
chr5	120470	125232	+	DDB_G0287315	DDB_G0287315	NA
chr5	125370	127208	-	DDB_G0287317	DDB_G0287317	similar to the cudA transcriptional regulator
chr5	129877	130923	+	DDB_G0287319	DDB_G0287319	similar to human SLC35E2 (solute carrier family 35 member E2)%3B contains 10 putative transmembrane domains
chr5	131270	131668	-	DDB_G0287321	DDB_G0287321	NA
chr5	131874	132648	-	DDB_G0287437	DDB_G0287437	NA
chr5	133013	134305	+	DDB_G0287323	DDB_G0287323	contains an N-terminal oxidoreductase domain and a partial C-terminal oxidoreductase domain%3B the Gfo%2FIdh%2FMocA family proteins utilize NADP or NAD
chr5	134806	136581	-	DDB_G0287297	p80	endosome %2F phagosome membrane protein%3B contains a putative signal peptide
chr5	137312	141128	+	DDB_G0287325	DDB_G0287325	similar to mammalian EPS15%2C a clathrin adaptor that binds to the AP2 alpha subunit in mammalian cells
chr5	141257	143280	-	DDB_G0287327	prmt5	Skb1 (Shk1 kinase-binding protein 1) family protein%3B ortholog of S. cerevisiae HSL7 and H. sapiens PRMT5 involved in methylation of small nuclear ribonucleoproteins
chr5	143681	144010	-	DDB_G0287329	DDB_G0287329	NA
chr5	144715	146939	+	DDB_G0287331	DDB_G0287331	contains one putative transmembrane domain
chr5	147100	148019	-	DDB_G0287333	eif3J	EIF3J ortholog%2C the eukaryotic initiation factor alpha subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%3B  is composed of at least 12 different subunits
chr5	148219	148494	+	DDB_G0287335	DDB_G0287335	has similarity to human cold inducible RNA binding protein (CIRBP)%2C however%2C it is considreably shorter
chr5	148729	149720	-	DDB_G0287439	DDB_G0287439	NA
chr5	150447	153588	+	DDB_G0287337	taf5	subunit of TFIID and SAGA complexes%2C involved in RNA polymerase II transcription initiation and in chromatin modification
chr5	154225	156434	+	DDB_G0287339	DDB_G0287339	NA
chr5	157067	158037	+	DDB_G0287341	DDB_G0287341	contains 4 putative transmembrane domains
chr5	158259	159262	-	DDB_G0287343	DDB_G0287343	NA
chr5	159445	160052	-	DDB_G0287345	ankrd39	NA
chr5	160889	162182	+	DDB_G0287441	DDB_G0287441	contains six predicted transmembrane domains%3B similar to a D. purpureum protein 
chr5	162247	164858	-	DDB_G0287347	DDB_G0287347	NA
chr5	165026	169507	-	DDB_G0287351	dhx37	ortholog of H. sapiens DHX37 and S. cerevisiae ECM16%2C an RNA helicase involved in ribosomal biosynthesis
chr5	169845	171686	-	DDB_G0287353	fdxr	catlyzes the reaction: reduced ferredoxin %2B NADP%2B %3D oxidized ferredoxin %2B NADPH %2B H%2B
chr5	172169	172294	-	DDB_G0287355	DDB_G0287355	NA
chr5	172540	174823	-	DDB_G0287357	DDB_G0287357	NA
chr5	175065	176646	-	DDB_G0287359	DDB_G0287359	NA
chr5	177577	180699	+	DDB_G0287445	DDB_G0287445	conserved protein%3B ortholog of the human C11orf2 (Chromosome 11 Open Reading Frame 2) protein%3B contains a putative Dor1 domain%2C which in yeast is involved in vesicle targeting to the Golgi apparatus and complexes with a number of other trafficking proteins
chr5	181547	183381	+	DDB_G0287417	DDB_G0287417	NA
chr5	183547	185657	-	DDB_G0287361	ddx41	conserved RNA helicase%3B ortholog of D. melanogaster DEAD box protein abstrakt%2C which is required during post-transcriptional gene expression
chr5	185922	187515	+	DDB_G0287447	DDB_G0287447	ortholog of the bacterial epsilon subunit of DNA polymerase III%2C a multisubunit enzyme responsible for most of the replicative synthesis in bacteria%3B the  contain the editing function and is a proofreading 3%27-5%27 exonuclease%3B the Dictyostelium gene is missing  approximately 100 amino acids at the carboxyl terminus
chr5	188514	189365	+	DDB_G0295689	DDB_G0295689	contains a predicted signal peptide and two transmembrane domains%3B has no known homologs
chr5	189973	191154	+	DDB_G0287449	DDB_G0287449	NA
chr5	191929	192312	+	DDB_G0287293	gerA	NA
chr5	192610	198990	-	DDB_G0287363	sibA	similar to the integrin beta family%3B cytosolic domain binds talin%3B involved in substrate adhesion and phagocytosis%3B%3Cbr%3E %3Cb%3Enote%3C%2Fb%3E%2C the sequence in dictyBase has mismatches and does not contain a clear signal sequence%2C whereas the published sequence available from the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FSibA%22%3Ecommunity annotation%3C%2Fa%3E page%3C%2Fb%3E contains a clear signal sequence
chr5	199757	203056	-	DDB_G0287365	DDB_G0287365	contains a putative signal peptide
chr5	204023	205085	+	DDB_G0287367	DDB_G0287367	conserved hypothetical protein
chr5	205200	206160	-	DDB_G0287369	DDB_G0287369	NA
chr5	206705	209270	+	DDB_G0287371	ada	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B adenosine %3C%3D%3E NH%3Csub%3E3%3C%2Fsub%3E %2B inosine in salvage pathways of nucleosides%3B contains two tandem repeats of the adenosine deaminase domain
chr5	209576	211979	-	DDB_G0287457	DDB_G0287457	NA
chr5	212611	216183	-	DDB_G0287295	forC	formin that contains an N-terminal GBD domain as well as FH2 and FH3 domains%2C but lacks the FH1 domain 
chr5	217435	218716	-	DDB_G0287373	DDB_G0287373	NA
chr5	219071	222043	+	DDB_G0287375	DDB_G0287375	NA
chr5	222824	228533	+	DDB_G0287291	abpD	actin binding protein that is developmentally and cAMP-regulated%3B associates with intracellular membranes
chr5	229012	229501	-	DDB_G0287451	DDB_G0287451_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0272881%22%3EDDB_G0272881%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0274039%22%3EDDB_G0274039%3C%2Fa%3E 
chr5	230145	232443	+	DDB_G0287377	mccA	catalyzes the reaction ATP %2B 3-methylcrotonoyl-CoA %2B HCO%3Csub%3E3%3C%2Fsub%3E%3Csup%3E-%3C%2Fsup%3E %3C%3D%3E ADP %2B phosphate %2B 3-methylglutaconyl-CoA
chr5	233763	237245	+	DDB_G0287379	DDB_G0287379	NA
chr5	237838	238680	+	DDB_G0287381	DDB_G0287381	NA
chr5	239046	239555	+	DDB_G0287383	DDB_G0287383	NA
chr5	239982	241528	+	DDB_G0287385	DDB_G0287385	contains 2 putative transmembrane domains
chr5	241597	242555	-	DDB_G0287387	DDB_G0287387	NA
chr5	243540	245846	+	DDB_G0287389	DDB_G0287389	NA
chr5	246455	247332	+	DDB_G0287391	ranbp1	ortholog of RanBP1
chr5	247623	250277	-	DDB_G0287393	mlh1	MLH1 ortholog%3B required for DNA mismatch repair
chr5	250770	251747	+	DDB_G0287395	DDB_G0287395	NA
chr5	251848	253973	-	DDB_G0287397	DDB_G0287397	belongs to a large superfamily of metalloenzymes
chr5	254727	254799	-	DDB_G0295297	tRNA-Ala-AGC-10	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr5	255717	257558	-	DDB_G0287399	DDB_G0287399	NA
chr5	257909	259024	-	DDB_G0287401	tmem164	conserved transmembrane protein%3B contains 7 putative transmembrane domains
chr5	259377	259921	-	DDB_G0287403	DDB_G0287403	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293208%22%3E%3Ci%3EDDB_G0293208%3C%2Fi%3E%3C%2Fa%3E
chr5	260619	262444	-	DDB_G0287405	DDB_G0287405	conserved protein of unknown function%3B contains 9 putative transmembrane domains
chr5	263392	268500	+	DDB_G0287407	DDB_G0287407	similar to nephrocystin 3%2C Grp94 neighboring nucleotidase%2C and other TPR repeat-containing proteins
chr5	268971	269043	-	DDB_G0295295	tRNA-Met-CAU-15	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr5	269267	270601	+	DDB_G0287409	DDB_G0287409_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr5	271707	274215	-	DDB_G0287411	DDB_G0287411	NA
chr5	274270	274935	+	DDB_G0287413	DDB_G0287413	NA
chr5	275303	278445	+	DDB_G0287415	DDB_G0287415	NA
chr5	278611	278683	-	DDB_G0295293	tRNA-Ile-AAU-11	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr5	278825	279385	+	DDB_G0287421	DDB_G0287421_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr5	280003	280852	-	DDB_G0287453	DDB_G0287453_ps	putative pseudogene%3B fragment%2C similar to EGF repeat-containing proteins %3Ca href%3D%22%2Fgene%2FDDB_G0286437%22%3EDDB_G0286437%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0307042%22%3EDDB_G0307042%3C%2Fa%3E
chr5	282346	284011	-	DDB_G0287455	DDB_G0287455_RTE	ORF of tRNA-specific long terminal repeat retrotransposon DGLT-A%3B refer to AF298204 for full-length element
chr5	284121	284191	+	DDB_G0295235	tRNA-Gly-GCC-12	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr5	284599	288928	-	DDB_G0287461	abcG3	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr5	290618	291886	-	DDB_G0287463	DDB_G0287463	NA
chr5	292797	294152	+	DDB_G0287465	DDB_G0287465	NA
chr5	294648	295029	-	DDB_G0287489	DDB_G0287489	NA
chr5	295392	297778	-	DDB_G0287467	gluS	catalyzes the reaction ATP %2B L-glutamate %2B tRNAGlu %3D AMP %2B diphosphate %2B L-glutamyl-tRNAGlu
chr5	298748	300499	+	DDB_G0287469	glud1	catalyzes the reaction L-glutamate %2B H%3Csub%3E2%3C%2Fsub%3EO %2B NAD(P)%3Csup%3E%2B%3C%2Fsup%3E %3D 2-oxoglutarate %2B ammonia %2B NAD(P)H %2B H%3Csup%3E%2B%3C%2Fsup%3E%3B acting on the CH-NH%3Csub%3E2%3C%2Fsub%3E group of donors with NAD%3Csup%3E%2B%3C%2Fsup%3E or NADP%3Csup%3E%2B%3C%2Fsup%3E as acceptor
chr5	300793	302173	-	DDB_G0287471	DDB_G0287471	contains a predicted signal peptide%3B %3B similar to Polysphondylium pallidum 64 kDa cell surface glycoprotein
chr5	302500	303974	-	DDB_G0287473	DDB_G0287473_ps	putative pseudogene%3B paramecium surface antigen repeat-containing protein family gene
chr5	304647	305960	-	DDB_G0295701	DDB_G0295701	contains a predicted signal peptide%3B contains a predicted signal peptide%3B similar to Polysphondylium pallidum 64 kDa cell surface glycoprotein
chr5	306749	308057	-	DDB_G0287483	cnrG	identified as a suppressor of smlA null mutant cnr6%3B contains a predicted signal peptide%3B similar to Polysphondylium pallidum 64 kDa cell surface glycoprotein 
chr5	308656	310036	-	DDB_G0287491	DDB_G0287491	contains a predicted signal peptide%3B similar to Polysphondylium pallidum 64 kDa cell surface glycoprotein
chr5	310846	311518	-	DDB_G0287493	DDB_G0287493_ps	putative pseudogene%3B paramecium surface antigen repeat-containing family  protein
chr5	312971	313780	-	DDB_G0287475	DDB_G0287475	NA
chr5	314532	316475	-	DDB_G0287477	DDB_G0287477	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%3B contains one putative transmembrane domain and an additional putative signal sequence
chr5	318028	320988	-	DDB_G0287459	secG	Arf-guanyl-nucleotide exchange factor of the cytohesin family%3B involved in chemotaxis to cAMP during development and substrate adhesion
chr5	323189	325069	-	DDB_G0287479	DDB_G0287479	NA
chr5	327483	329575	+	DDB_G0287503	DDB_G0287503	NA
chr5	329850	333647	+	DDB_G0287497	nup133	component of the nuclear pore complex%2C which plays a role in RNA export
chr5	334067	334735	+	DDB_G0287495	pyrK	phosphorylates dCMP and dUMP to dCDP and dUDP%2C respectively
chr5	334918	336042	-	DDB_G0287499	DDB_G0287499	NA
chr5	336533	340327	-	DDB_G0287501	DDB_G0287501	similar to polyketide synthases%2C but missing more than half of the amino terminus
chr5	341417	342545	-	DDB_G0287509	DDB_G0287509	similar to bacterial 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase%2C which catalyzes the reaction 1%2C4-dihydroxy-2-naphthoate %2B polyprenylpyrophosphate %3C%3D%3E demethylmenaquinone-8 %2B pyrophosphate %2B CO%3Csub%3E2%3C%2Fsub%3E%2C and similar to mammalian transitional epithelia response protein%2C of unknown function
chr5	343078	347016	-	DDB_G0287511	DDB_G0287511	belongs to a large D. discoideum protein family of unknown function
chr5	347764	349166	+	DDB_G0287565	DDB_G0287565_ps	putative pseudogene%3B similar to a family of Zinc finger%2C N-recognin domain-containing Dictyostelium proteins
chr5	349945	351613	-	DDB_G0287513	jcdG	conserved protein%3B similar to H. sapiens C14orf169
chr5	352517	354132	+	DDB_G0287515	tat	catalyzes the reaction L-tyrosine %2B 2-oxoglutarate %3C%3D%3E 4-hydroxyphenylpyruvate %2B L-glutamate
chr5	354336	359323	-	DDB_G0287569	agl	multifunctional protein that plays a role in glycogen catabolism
chr5	360366	360944	-	DDB_G0287517	DDB_G0287517	NA
chr5	361279	361988	+	DDB_G0287507	limD1	binds to F-actin%3B contributes to the maintenance of the cortical actin cytoskeleton
chr5	362168	363766	-	DDB_G0287519	DDB_G0287519	catalyzes the reaction acetoacetyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO %3D CoA %2B acetoacetate
chr5	364712	366226	-	DDB_G0287521	DDB_G0287521	ortholog of the conserved signal peptide peptidase-like 3 (SPPL3)%3B contains 8 predicted transmembrane domains and an additional N-terminal signal sequence
chr5	366594	366936	-	DDB_G0287525	DDB_G0287525	NA
chr5	367089	367767	+	DDB_G0287527	DDB_G0287527	NA
chr5	367808	369553	+	DDB_G0287571	DDB_G0287571	NA
chr5	369718	371186	-	DDB_G0287529	DDB_G0287529	NA
chr5	373625	374880	+	DDB_G0287533	DDB_G0287533	NA
chr5	376738	384911	+	DDB_G0287505	talB	talin with an unusual villin headpiece-like domain%3B involved in multicellular development and in autophagic cell death
chr5	385388	387235	+	DDB_G0287535	DDB_G0287535	NA
chr5	388563	391608	-	DDB_G0287537	nop14	ortholog of S. cerevisiae NOP14 involved in rRNA processing
chr5	391871	393563	-	DDB_G0287573	DDB_G0287573	NA
chr5	393959	396079	+	DDB_G0287575	DDB_G0287575	NA
chr5	396188	397030	-	DDB_G0287539	cutc	copper homeostasis protein conserved from bacteria to human
chr5	397759	399876	+	DDB_G0287541	DDB_G0287541	NA
chr5	400560	401147	+	DDB_G0287543	DDB_G0287543	very similar to H. sapiens B-cell receptor-associated protein 29 and 31 (BCAP29%2F31) and S. cerevisiae endoplasmic reticulum transmembrane protein 1 and 3 (YET1%2F3)%3B contains a putative signal peptide and two transmembrane domains
chr5	401763	403091	+	DDB_G0287545	DDB_G0287545	NA
chr5	403298	404706	-	DDB_G0287547	DDB_G0287547	NA
chr5	405148	405534	-	DDB_G0287549	DDB_G0287549	NA
chr5	406658	408025	+	DDB_G0287551	DDB_G0287551	NA
chr5	408133	408812	-	DDB_G0287553	rab7B	there is another rab7 homolog%2C %3Ci%3Erab7A%3C%2Fi%3E
chr5	409584	409654	-	DDB_G0295291	tRNA-Gly-GCC-13	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr5	412142	413043	+	DDB_G0287555	DDB_G0287555	catalyzes the reaction L-cysteine %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E 3-sulfinoalanine
chr5	413359	416933	-	DDB_G0287577	manG	NA
chr5	417964	419093	+	DDB_G0287557	pno1	conserved protein%3B in S. cerevisiae%2C a nucleolar protein required for pre-18S rRNA processing
chr5	419276	419854	-	DDB_G0287559	DDB_G0287559	NA
chr5	420291	421842	-	DDB_G0287561	DDB_G0287561	NA
chr5	422254	423174	-	DDB_G0287563	mut	catalyzes the reaction (R)-methylmalonyl-CoA %3D succinyl-CoA%3B vitamin B12 dependent%3B based on similarity with other MUT enzymes%2C this protein is truncated at the N-terminus and might not be catalytically active%3B the fragment contains the B12 binding site
chr5	424020	425292	-	DDB_G0287579	DDB_G0287579_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr5	428287	429322	-	DDB_G0295777	DDB_G0295777	NA
chr5	432078	432159	-	DDB_G0295289	tRNA-Leu-AAG-7	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr5	433923	434939	+	DDB_G0287581	DDB_G0287581	putative extracellular protein%2C contains a predicted N-terminal signal sequence
chr5	436285	440337	+	DDB_G0287651	DDB_G0287651	belongs to a large D. discoideum protein family of unknown function%3B this protein is a putative guanylate cyclase family protein
chr5	441079	442796	+	DDB_G0287653	thoc6	ortholog of THOC6%2C which exists in the THO complex required for transcriptional elongation
chr5	443153	444172	+	DDB_G0287655	DDB_G0287655	NA
chr5	444388	446676	-	DDB_G0287657	tpsA	CAZy family GT20%3B contains an N-terminal glycosyltransferase domain and a C-terminal trehalose-phosphatase domain%3B enriched in prestalk cells 
chr5	447833	449624	+	DDB_G0287659	nagD	catalyses the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
chr5	449924	451697	+	DDB_G0287597	nagC	catalyses the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
chr5	452628	453071	+	DDB_G0287599	DDB_G0287599	NA
chr5	453256	453654	-	DDB_G0287601	DDB_G0287601	NA
chr5	453942	454447	-	DDB_G0287603	DDB_G0287603	NA
chr5	454900	456713	-	DDB_G0287605	tgrP1	contains a predicted signal peptide
chr5	458523	459957	-	DDB_G0287649	pldY	highly similar to mammalian PLD3%2C which is of unknown function
chr5	460750	461133	+	DDB_G0287583	gerC	NA
chr5	461888	462739	+	DDB_G0287587	smlA	cytosolic protein present in vegetative and developing cells
chr5	463300	464157	-	DDB_G0287607	pcna	subunit of DNA polymerase holoenzyme that clamps the replicating polymerase to DNA
chr5	464998	466011	+	DDB_G0287609	DDB_G0287609	highly similar to cinB (94%25 identity)
chr5	466151	467057	-	DDB_G0287611	DDB_G0287611	NA
chr5	467594	468956	-	DDB_G0287613	DDB_G0287613	NA
chr5	470940	473288	+	DDB_G0287615	DDB_G0287615	NA
chr5	473577	477073	-	DDB_G0287661	spt5	ortholog of the human SUPT5H and S. cerevisiae SPT5 (suppressor of Ty 5)%2C a transcription-elongation factor that is tightly associated in a complex with SPT4
chr5	477935	478456	-	DDB_G0287663	DDB_G0287663	NA
chr5	479630	480509	+	DDB_G0287617	DDB_G0287617	similar to Bax inhibitor 1%2C that may have a role in inhibition of apoptosis%3B contains 7 transmembrane domains
chr5	482074	483315	+	DDB_G0287619	gmppB	catalyzes the reaction GTP %2B alpha-D-mannose 1-phosphate %3C%3D%3E diphosphate %2B GDP-mannose
chr5	483890	486632	+	DDB_G0287621	DDB_G0287621	NA
chr5	486671	488637	-	DDB_G0287623	DDB_G0287623	NA
chr5	489912	492994	-	DDB_G0287625	DDB_G0287625	NA
chr5	494298	494849	+	DDB_G0287627	timm17	conserved component of the mitochondrial presequence translocase-associated protein import motor (PAM) required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix
chr5	494968	496392	-	DDB_G0287595	pgkA	catalyzes the reaction 3-phosphoglycerate %2B ATP %3C%3D%3E 3-phospho-D-glyceroyl-phosphate %2B ADP%3B binds and is regulated by calmodulin
chr5	496993	497681	+	DDB_G0287629	rbx1	highly similar to mammalian RBX1
chr5	498740	501372	+	DDB_G0287585	rgaA	NA
chr5	501928	505784	+	DDB_G0287665	DDB_G0287665	NA
chr5	506343	508648	+	DDB_G0287667	DDB_G0287667	NA
chr5	510322	510750	+	DDB_G0287669	hdaC_ps1	putative pseudogene%3B small fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0280195%22%3E%3Ci%3EhdaC%3C%2Fi%3E%3C%2Fa%3E 
chr5	512195	512985	+	DDB_G0287671	DDB_G0287671	NA
chr5	513198	513521	+	DDB_G0287673	DDB_G0287673	NA
chr5	514890	515059	+	DDB_G0348143	DDB_G0348143	NA
chr5	515703	517132	+	DDB_G0287675	DDB_G0287675	NA
chr5	517253	519814	-	DDB_G0287591	DDB_G0287591	NA
chr5	520445	524477	-	DDB_G0287589	abcC14	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr5	525231	529373	-	DDB_G0287593	abcC6	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr5	530347	532137	-	DDB_G0287631	glk	catalyzes the reaction ATP %2B D-glucose %3C%3D%3E ADP %2B D-glucose 6-phosphate
chr5	532724	533193	+	DDB_G0287633	DDB_G0287633	weakly similar to S. cerevisiae SEM1%2C a short acidic protein which regulates exocyst function and pseudohyphal differentiation
chr5	533367	535169	-	DDB_G0287635	prpf4	ortholog of the prp4 splicing factor%2C component of the U4%2FU6-U5 snRNP complex%3B contains 7 WD repeats and a splicing factor motif
chr5	536098	537885	+	DDB_G0287637	mybD	contains one Myb DNA-binding domain
chr5	538405	540646	+	DDB_G0287639	DDB_G0287639	NA
chr5	540812	541420	-	DDB_G0287641	DDB_G0287641	NA
chr5	541940	543075	-	DDB_G0287677	DDB_G0287677	similar to NAD-dependent epimerase%2Fdehydratase family proteins that use nucleotide-sugar substrates for a variety of chemical reactions%3B contains a partial NmrA-like domain near the N-terminus
chr5	543713	544712	-	DDB_G0287643	DDB_G0287643	contains a putative N-terminal signal peptide
chr5	545368	549255	-	DDB_G0287679	DDB_G0287679	NA
chr5	550085	552643	+	DDB_G0287645	DDB_G0287645	similar to the human transmembrane protein 112%3B contains 5 putative transmembrane domains
chr5	552795	554153	-	DDB_G0287647	DDB_G0287647	NA
chr5	554899	559973	-	DDB_G0287681	grlR	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr5	566252	568397	+	DDB_G0287695	DDB_G0287695	NA
chr5	569375	572151	+	DDB_G0287697	DDB_G0287697	NA
chr5	573108	575336	+	DDB_G0287699	DDB_G0287699	NA
chr5	575637	576617	+	DDB_G0287701	DDB_G0287701	contains a predicted signal peptide
chr5	576895	582238	-	DDB_G0287703	DDB_G0287703	NA
chr5	582459	583580	-	DDB_G0287705	DDB_G0287705	NA
chr5	584047	584459	+	DDB_G0287707	rpc11	component of the RNA polymerase III complex%3B ortholog of H. sapiens RPC10 and S. cerevisiae RPC11
chr5	584610	587416	-	DDB_G0287709	DDB_G0287709	NA
chr5	588099	589683	-	DDB_G0287711	DDB_G0287711	belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B homolog of human AADAT (kynurenine%2Falpha-aminoadipate aminotransferase) and S. cerevisiae ARO8 (aromatic amino acid aminotransferase)
chr5	591245	592192	-	DDB_G0287869	DDB_G0287869	NA
chr5	594468	596120	+	DDB_G0287713	DDB_G0287713	NA
chr5	596372	596655	-	DDB_G0287715	DDB_G0287715	NA
chr5	597404	598609	+	DDB_G0287717	iliD	similar to hypothetical fungi proteins%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr5	598885	599170	-	DDB_G0287719	DDB_G0287719	NA
chr5	600318	601358	+	DDB_G0287721	DDB_G0287721	NA
chr5	601565	604462	-	DDB_G0287723	DDB_G0287723	NA
chr5	605033	606859	+	DDB_G0287725	DDB_G0287725	NA
chr5	607163	608312	-	DDB_G0287871	DDB_G0287871	NA
chr5	609137	612530	+	DDB_G0287727	DDB_G0287727	NA
chr5	613467	615948	+	DDB_G0287729	DDB_G0287729	NA
chr5	616064	616713	-	DDB_G0287731	DDB_G0287731	belongs to the PLAC8 family (placenta-specific gene 8 protein)%2C a family of cysteine-rich proteins with highly divergent%2C low complexity amino terminal regions
chr5	617723	619024	+	DDB_G0287733	syn7A	member of the SNARE family (Soluble NSF Attachment Protein REceptor)%3B plays a role in endosomal fusion
chr5	620499	621987	+	DDB_G0287735	DDB_G0287735	catalyzes the reaction a 5%27-ribonucleotide %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E a ribonucleoside %2B phosphate
chr5	622124	629068	-	DDB_G0287873	DDB_G0287873	NA
chr5	630862	634614	+	DDB_G0287875	dydA	required for cell polarization and directional movement during chemotaxis%3B contains a calponin-like actin binding domain%2C a pleckstrin homology domain%2C and two ras association domains
chr5	635143	635948	-	DDB_G0287737	DDB_G0287737	contains five transmembrane domains
chr5	636584	638270	-	DDB_G0287739	arpH	similar to mammalian and yeast actin related protein 10%2C part of the dynactin complex
chr5	638654	640059	-	DDB_G0287741	DDB_G0287741	might be involved in fatty acid metabolism
chr5	640479	641078	+	DDB_G0287743	DDB_G0287743	NA
chr5	641447	644230	+	DDB_G0287877	DDB_G0287877	NA
chr5	644291	646451	-	DDB_G0287745	DDB_G0287745	putative ortholog of human cdk5rap3%2FLZAP%2C an ARF binding protein involved in cell cycle regulation
chr5	647248	648026	-	DDB_G0287749	DDB_G0287749	NA
chr5	648202	649991	+	DDB_G0287751	DDB_G0287751	contains a putative RUN domain
chr5	650440	651721	+	DDB_G0287879	DDB_G0287879	NA
chr5	652393	655565	-	DDB_G0287881	exoc5	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr5	656012	656982	+	DDB_G0287753	DDB_G0287753	NA
chr5	657459	657908	-	DDB_G0302511	rpl39	protein component of the large (60S) ribosomal subunit
chr5	658379	661019	-	DDB_G0287755	mad1	conserved component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate%3B localized to centromeres during mitosis
chr5	661336	662528	+	DDB_G0287757	DDB_G0287757	ortholog of the conserved IMPACT (Imprinted and ancient) protein%2C a translational regulator that ensures constant high levels of translation under amino acid starvation
chr5	662849	664132	-	DDB_G0287759	DDB_G0287759	NA
chr5	664647	666355	-	DDB_G0287761	DDB_G0287761	NA
chr5	667105	668784	-	DDB_G0287857	DDB_G0287857	NA
chr5	669499	670273	+	DDB_G0287763	DDB_G0287763	similar to D. melanogaster slv (saliva) and human RAG1AP1%3B RAG1AP1 facilitates gene activation of recombination activating gene 1%3B contains 2 MtN3_slv domains%3B contains 7 putative transmembrane domains
chr5	670518	671507	+	DDB_G0287885	DDB_G0287885	NA
chr5	671692	673096	-	DDB_G0287765	DDB_G0287765	overexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr5	675515	675708	+	DDB_G0287767	DDB_G0287767_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0287763%22%3EDDB_G0287763%3C%2Fa%3E 
chr5	675763	677136	-	DDB_G0287769	ndufaf5	conserved mitochondrial complex I (CI) assembly factor%2C which when mutated in human leads to mitochondrial disease%3B in %3Ci%3EDictyostelium%3C%2Fi%3E%2C mutations in the ndufaf5 gene cause defects in growth and development%2C and autophagy is increased.
chr5	677716	678399	+	DDB_G0287771	DDB_G0287771	NA
chr5	678742	679484	+	DDB_G0287773	gcvH1	lipoylprotein that is reduced as it shuttles the methylamine group of glycine from the P-protein to the T-protein
chr5	679687	681762	-	DDB_G0287775	ptcC	NA
chr5	682723	683036	+	DDB_G0287777	sec61g	gamma subunit of the SEC61 complex (composed of %3Ca href%3D%22%2Fgene%2FDDB_G0278885%22%3ESec61a%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0278117%22%3ESec61b%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0287777%22%3ESec61g%3C%2Fa%3E) involved in protein targeting to the membrane
chr5	683410	686250	-	DDB_G0287779	arpG	similar to the actin related protein ARP8%2C in mammalian called ACTR8%2C a putative component of a chromatin-remodeling complex
chr5	687490	687987	+	DDB_G0287783	DDB_G0287783	has similarity to the mammalian ubiquitin-associated domain-containing protein 2 (UBAC2)
chr5	688286	689217	-	DDB_G0287693	ubc9	NA
chr5	689907	692602	-	DDB_G0287685	cinC	translocates peptidyl-tRNA from the aminoacyl site to the peptidyl site on the ribosome during protein synthesis%3B induced by cycloheximide%3B knockdown has significantly reduced ability for protein synthesis
chr5	694189	699162	+	DDB_G0287859	DDB_G0287859	contains a putative N-end rule-based degradation signal%2C which targets a protein for ubiquitin-dependent proteolysis
chr5	699242	700199	-	DDB_G0287785	abcG_ps1	putative pseudogene%3B similar to abcG family proteins
chr5	701445	703319	-	DDB_G0287787	DDB_G0287787_ps	putative pseudogene%3B similar to many different classes of protein kinases
chr5	703769	704535	-	DDB_G0287789	DDB_G0287789_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0281501%22%3EDDB_G0281501%3C%2Fa%3E
chr5	706104	706487	-	DDB_G0287687	gerB	expressed specifically during spore germination
chr5	707217	708704	-	DDB_G0287689	tubA	monomeric subunit of microtubules%3B as most other species%2C Dicty has two alpha-tubulin genes%2C and  only one of each beta- and gamma-tubulin%3B the other alpha tubulin gene is %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FtubA2%22%3EtubA2%3C%2Fa%3E
chr5	709302	709832	+	DDB_G0287791	gcvH3	lipoylprotein that is reduced as it shuttles the methylamine group of glycine from the P-protein to the T-protein
chr5	710171	710938	+	DDB_G0287793	DDB_G0287793	similar to human GSTT2 (glutathione S-transferase theta-2)%3B glutathione transferases participate in the detoxification of reactive electrophilic compounds by catalysing their conjugation to glutathione%3B contains a predicted peroxisomal targeting signal
chr5	711021	711650	-	DDB_G0287795	gcvH4	lipoylprotein that is reduced as it shuttles the methylamine group of glycine from the P-protein to the T-protein
chr5	711961	712452	-	DDB_G0287861	gcvH5	lipoylprotein that is reduced as it shuttles the methylamine group of glycine from the P-protein to the T-protein
chr5	712716	712805	-	DDB_G0295287	tRNA-Thr-UGU-6	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr5	713390	715477	-	DDB_G0287797	DDB_G0287797	NA
chr5	715755	721476	+	DDB_G0287799	DDB_G0287799	contains a putative N-end rule-based degradation signal%2C which targets a protein for ubiquitin-dependent proteolysis
chr5	721592	724251	-	DDB_G0287801	ncstn	component of the gamma-secretase complex%2C which executes the intramembrane proteolysis of type I integral membrane proteins
chr5	724797	727092	+	DDB_G0287803	argS2	catalyzes the reaction ATP %2B L-arginine %2B tRNAArg %3D AMP %2B diphosphate %2B L-arginyl-tRNAArg
chr5	727908	732112	+	DDB_G0287855	pirA	Rac-binding component of SCAR regulatory complex
chr5	733543	739332	+	DDB_G0287863	DDB_G0287863	developmental expression pattern altered in GBF null cells%3B highly repetitive protein%2C serine and glycine rich%3B contains a predicted signal peptide
chr5	739515	744435	-	DDB_G0287805	DDB_G0287805	contains a putative N-terminal signal sequence and one predicted C-terminal transmembrane domain
chr5	744839	746432	-	DDB_G0287807	DDB_G0287807	contains a putative N-terminal signal sequence and one predicted C-terminal transmembrane domain
chr5	746961	747812	-	DDB_G0287809	DDB_G0287809	NA
chr5	748966	749441	+	DDB_G0287811	DDB_G0287811	similar to mitochondrial chaperonin 10 proteins
chr5	749668	750615	-	DDB_G0287889	DDB_G0287889	NA
chr5	751626	755503	+	DDB_G0287891	bms1l	nucleolar protein involved in the biosynthesis of the 40S ribosomal subunit
chr5	756116	757297	+	DDB_G0287813	DDB_G0287813	NA
chr5	758176	760474	+	DDB_G0287815	DDB_G0287815	weak ortholog of the conserved chromatin assembly factor 1 (CAF1) subunit A%3Cbr%3E %3Cb%3ENote:%3C%2Fb%3E Do not confuse this gene with %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277827%22%3E%3Ci%3EcafA%3C%2Fi%3E%3C%2Fa%3E%2C calfumirin 1%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Although the homology of DDB_G0287815 to CAF1%2C subunit A is weak%2C the assignment is supported  by the fact that this gene is overexpressed sevenfold in a Dicty strain in which  the retinoblastoma-like gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E%2C is disrupted (Doquang et al%2C in preparation).  Most genes with roles in S-phase or mitosis are overexpressed in this strain.  Chromatin assembly is of course a part of normal DNA replication%2C and %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269800%22%3EDDB_G0269800%3C%2Fa%3E%2C provisionally assigned as CAF1%2C subunit A%2C is similarly overexpressed in the rblA null.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C September 2009 %3C%2Fi%3E
chr5	760582	764012	-	DDB_G0287817	wdr24	NA
chr5	764642	765139	-	DDB_G0287819	ecmK	NA
chr5	765881	766378	-	DDB_G0287821	DDB_G0287821	NA
chr5	766914	770093	-	DDB_G0287823	lrrB	contains an SH2 domain%3B regulates growing cell and developmental gene expression
chr5	771339	772816	+	DDB_G0287825	DDB_G0287825	NA
chr5	772980	773415	-	DDB_G0287827	pfdn1	component of the prefoldin complex responsible for targeting proteins to cytosolic chaperonin CCT
chr5	773675	776221	-	DDB_G0287829	ecd	ortholog of the eukaryotic SGT1 or ECD%2C a putative transcription coactivator
chr5	776635	778358	+	DDB_G0287831	DDB_G0287831	NA
chr5	779158	783577	+	DDB_G0287833	DDB_G0287833	NA
chr5	783822	784223	-	DDB_G0287835	DDB_G0287835	NA
chr5	784589	785242	-	DDB_G0287893	DDB_G0287893	NA
chr5	787959	788696	+	DDB_G0287837	DDB_G0287837	NA
chr5	789237	790688	+	DDB_G0287839	DDB_G0287839	NA
chr5	792495	797051	+	DDB_G0287691	abcC3	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr5	797545	798867	-	DDB_G0287841	DDB_G0287841	NA
chr5	800059	802971	+	DDB_G0287895	gacM	NA
chr5	803720	805540	-	DDB_G0287897	DDB_G0287897	NA
chr5	806278	808319	-	DDB_G0287843	DDB_G0287843	NA
chr5	809663	812425	-	DDB_G0287845	DDB_G0287845	NA
chr5	813389	816054	+	DDB_G0287847	DDB_G0287847	NA
chr5	816399	820519	+	DDB_G0287899	rif1	ortholog of RIF1%2C associated with the telomeres and in human%2C required for checkpoint mediated arrest of cell cycle progression in response to DNA damage during S-phase %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  In budding yeast%2C RIF1 is a telomere-associated protein which has been shown to  suppress the recruitment of the ATM DNA-damage signalling complex to the telomere ends%2C  and play a role in telomere length regulation  (see %3Ca href%3D%22http:%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F19217405%22%3EHirano et al 2009%3C%2Fa%3E).  rif1 is overexpressed fifteenfold in the Dictyostelium %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E%2C a strain in  which most genes associated with cell cycle progression are overexpressed  (Doquang et al%2C in preparation).  This suggests an active role of rif1 in telomere replication.   %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C September 2009 %3C%2Fi%3E   %3Cbr%2F%3E%3Cbr%2F%3E The mode of action of RIF1 seems different in fungi compared to other eukaryotes%2C at least with respect to RAP1 interaction:  First%2C there does not seem to be orthologs of the S. cerevisiae RAP1 (Repressor Activator Protein) outside the fungi.  Secondly%2C the S. pombe ortholog does not interact with rap1%3B see %3Ca href%3D%22http:%2F%2Fwww.genedb.org%2Fgenedb%2FSearch?organism%3Dpombe%26name%3DSPAC6F6.17%22%3ESPAC6F6.17%3C%2Fa%3E %3Cbr%2F%3E %3Ci%3EPascale Gaudet November 2009  %3C%2Fi%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Frif1%22%3E There is more information on the wiki page%3C%2Fa%3E. 
chr5	820586	821272	-	DDB_G0287849	trxD	small disulphide-containing redox protein that serves as a general protein disulphide oxidoreductase
chr5	822730	825733	+	DDB_G0287851	DDB_G0287851	homolog of human IDE (insulin-degrading enzyme) and S. pombe zinc protease mug138
chr5	826726	829401	+	DDB_G0287853	mkcC	kinase domain very similar to those of Dictyostelium mkcA and mkcB%2C and other mitogen-activated protein kinases (Ste20%2FPAK family)
chr5	829648	829923	-	DDB_G0287865	DDB_G0287865	NA
chr5	830599	830875	-	DDB_G0287903	DDB_G0287903	NA
chr5	833038	833884	+	DDB_G0287907	DDB_G0287907	NA
chr5	833953	837758	-	DDB_G0287909	DDB_G0287909	NA
chr5	838039	839591	-	DDB_G0287911	DDB_G0287911	NA
chr5	841784	843034	+	DDB_G0287913	oatA	catalyzes the reaction L-ornithine %2B a 2-oxo acid %3D L-glutamate 5-semialdehyde %2B an L-amino acid
chr5	852371	855943	-	DDB_G0287943	DDB_G0287943	NA
chr5	857146	859073	+	DDB_G0287925	DG1037	NA
chr5	859603	861202	+	DDB_G0287927	DDB_G0287927	NA
chr5	861720	863096	+	DDB_G0287929	DDB_G0287929	NA
chr5	863622	864128	+	DDB_G0287931	DDB_G0287931	NA
chr5	864291	866314	-	DDB_G0287933	DDB_G0287933	caspases (Cysteine-dependent ASPartyl-specific proteASE) are cysteine peptidases that belong to the peptidase family C14
chr5	867361	869571	-	DDB_G0287935	DDB_G0287935	NA
chr5	871082	872062	-	DDB_G0287937	bxdc2	ortholog of the H. sapiens BXDC2 and S. cerevisiae BRX1%2C a nucleolar protein involved in the assembly of the large ribosomal subunit
chr5	872348	873521	-	DDB_G0287939	nit2	similar to mammalian NIT2 and to S. pombe SPAC26A3.11 amidohydrolase
chr5	874209	874841	-	DDB_G0287947	DDB_G0287947	NA
chr5	875204	876358	+	DDB_G0287949	DDB_G0287949	NA
chr5	876413	880841	-	DDB_G0287951	DDB_G0287951	carboxyl terminus is highly similar to Ataxin-7-like protein 3%3B the rest of the protein is extremely repetitive
chr5	881632	884917	-	DDB_G0287953	psmD1	contains armadillo-like helical binding domain
chr5	885768	887095	+	DDB_G0287955	DDB_G0287955	NA
chr5	887341	889297	+	DDB_G0287965	nae1	conserved regulatory subunit of the dimeric UBA3-NEA1 E1 enzyme%2C which activates NEDD8%3B necessary for cell cycle progression through the S-M checkpoint
chr5	889459	891081	-	DDB_G0287957	DDB_G0287957	NA
chr5	892450	892718	-	DDB_G0287963	DDB_G0287963	NA
chr5	893285	894013	+	DDB_G0287959	DDB_G0287959	putative copper transporter%2C contains 3 predicted transmembrane domains
chr5	894476	900405	-	DDB_G0287961	DDB_G0287961	DENN domains are present in proteins involved in Rab signaling
chr5	902212	904687	+	DDB_G0287967	DDB_G0287967	NA
chr5	912043	914306	+	DDB_G0287969	cnrN	phosphatase%2C identified as a suppressor of smlA null mutant cnr14%3B  involved in late-aggregation events including the regulation of fruiting body size%2C as well as cAMP and PI3K signaling%3B necessary for the proliferation inhibitory effects of AprA and CfaD%2C also required for chemorepulsion by AprA
chr5	914990	916793	-	DDB_G0287971	DDB_G0287971	NA
chr5	917728	918759	+	DDB_G0287973	DDB_G0287973	NA
chr5	919012	919619	-	DDB_G0287975	DDB_G0287975	NA
chr5	919913	921703	-	DDB_G0287977	ftcd	folate-dependent enzyme displaying both transferase and deaminase activity%3B defects of FTCD in human  cause glutamate formiminotransferase deficiency also known as formiminoglutamicaciduria (FIGLU-uria)
chr5	922041	925295	-	DDB_G0287979	DDB_G0287979	NA
chr5	925837	927081	-	DDB_G0287981	act33	similar to macronuclear actin 1 of ciliates%3B also similar to A. thaliana ACT11
chr5	927535	929520	+	DDB_G0287983	redC	similar to the %3Ci%3EH. sapiens%3C%2Fi%3E NDOR1%2C an oxidoreductase that catalyzes the NADP-dependent reduction of cytochrome c and one-electron acceptors
chr5	929613	931763	-	DDB_G0288055	DDB_G0288055	belongs to a family of conserved potassium transporters in bacteria%2C yeast%2C and plants%3B overexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants%3B contains 12 putative transmembrane domain
chr5	933669	934580	+	DDB_G0287985	DDB_G0287985	NA
chr5	934832	937482	+	DDB_G0287987	elp	similar to elongation factor 2 (EF-2) but lacks the EF-Tu binding domain 2 and EF-G domain%3B EF-2 translocates peptidyl-tRNA from the aminoacyl site to the peptidyl site on the ribosome during protein synthesis
chr5	937712	938860	-	DDB_G0287989	DDB_G0287989	NA
chr5	939192	940113	-	DDB_G0287991	DDB_G0287991	NA
chr5	940480	941265	-	DDB_G0287993	vps60	ortholog of yeast VPS60 and human CHMP5 (CHromatin Modifying Protein 5)%2C which associates with the ESCRT-III complex (endosomal sorting complex required for transport)
chr5	942400	942965	+	DDB_G0287995	rplp1B	NA
chr5	944155	948475	+	DDB_G0287997	ptcD	NA
chr5	948929	952644	+	DDB_G0287999	DDB_G0287999	NA
chr5	953191	957006	+	DDB_G0288001	DDB_G0288001	related to fatty acyl-CoA synthetase%3B catalyzes the reaction ATP %2B a long-chain carboxylic acid %2B CoA %3D AMP %2B diphosphate %2B an acyl-CoA%3B mediates the retrieval of fatty acids from endosomes to the cytoplasm
chr5	957063	961683	-	DDB_G0288003	DDB_G0288003	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr5	962125	963302	-	DDB_G0288005	DDB_G0288005	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr5	963824	969573	-	DDB_G0288007	DDB_G0288007	NA
chr5	970396	973445	+	DDB_G0288009	DDB_G0288009	putative ortholog of human UPF0663%2C downregulated in multiple cancers
chr5	974125	975231	+	DDB_G0288011	DDB_G0288011	NA
chr5	975395	976150	-	DDB_G0288013	DDB_G0288013	NA
chr5	977719	978288	+	DDB_G0288015	arrH	%3Cb%3ECommunity annotations: %3C%2Fb%3E The arrH%2C arrJ and arrK genes%2C and no others of the arrX group%2C are strongly (6 to 30-fold) overexpressed in a Dictyostelium strain in which the retinoblastoma-like gene rblA has been disrupted. Most of the genes overexpressed in this strain are associated with cell cycle progression%2C and this suggests that the main role of the corresponding proteins is in S-phase or mitosis. Human Arf1 has been reported to be essential for Golgi complex fragmentation during mitosis (Tang et al%2C JBC 283%2C 6085-94 (2008)%3B Xiang et al%2C JBC 282%2C 21829-37 (2007). It thus seems possible that ArrH%2C ArrJ and ArrK are involved in this process in Dicty. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E%3Cbr%2F%3E%3Cbr%2F%3E We have found very similar results including human%2C C. elegans and D. melanogaster sequences in the set of proteins used for the tree. See Weeks G%2C Gaudet P%2C and Insall RH. (2005) The small GTPase superfamily. in Dictyostelium Genomics. Horizon Bioscience. %3Ci%3E Pascale Gaudet%2C October 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FArrH%22%3E There are phylogenetic trees and more information on the wiki page%3C%2Fa%3E
chr5	978356	979732	-	DDB_G0288017	DDB_G0288017	NA
chr5	981451	982302	-	DDB_G0288019	DDB_G0288019	NA
chr5	983015	983954	-	DDB_G0288057	DDB_G0288057	NA
chr5	985635	988399	+	DDB_G0288021	atg6B	homolog of S. cerevisiae ATG6 and H. sapiens beclin (BECN1)%2C involved in autophagy and apoptosis
chr5	988438	989793	-	DDB_G0288023	DDB_G0288023	NA
chr5	990248	991999	-	DDB_G0288025	hal	catalyzes the reaction L-histidine %3D urocanate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr5	992896	994678	-	DDB_G0288027	ptcB	antisense inhibition of ptcB expression leads to slower growth%3B localizes to the mitochondria
chr5	994876	995849	-	DDB_G0288029	DDB_G0288029	member of the aspartate%2Fglutamate%2Furidylate kinase family%3B similar to glutamate 5-kinase
chr5	996657	1003385	+	DDB_G0288031	DDB_G0288031	large protein with cysteine-containing leucine-rich repeats and a C-terminal villin headpiece%3B contains an unknown domain (residues 300-620) found in different species and in several %3Ci%3EDictyostelium%3C%2Fi%3E proteins%2C represented in Pfam-B domains PB008617 and PB046085
chr5	1003620	1004488	-	DDB_G0288033	DDB_G0288033	NA
chr5	1006610	1007131	+	DDB_G0288035	DDB_G0288035	NA
chr5	1008144	1008590	-	DDB_G0288037	DDB_G0288037	NA
chr5	1009340	1010199	+	DDB_G0288039	DDB_G0288039	NA
chr5	1011026	1020812	+	DDB_G0288041	DDB_G0288041	NA
chr5	1021151	1022191	-	DDB_G0288043	DDB_G0288043	NA
chr5	1024941	1026749	+	DDB_G0288045	DDB_G0288045	NA
chr5	1026957	1028573	-	DDB_G0288047	dnmA	methylates cytosines in DNA%3B belongs to the dnmt2 subfamily%2C which has weak methylase activity
chr5	1029614	1030307	+	DDB_G0288059	DDB_G0288059	NA
chr5	1030842	1032427	+	DDB_G0288061	p2xE	member of the Dictyostelium P2X receptor family%3B membrane ion channel activated by ATP%3B may be involved in intracellular calcium signaling
chr5	1032772	1034031	+	DDB_G0288049	DDB_G0288049_ps	putative pseudogene%3B fragment of group of large D. discoideum proteins including %3Ca href%3D%22%2Fgene%2FDDB_G0277659%22%3EDDB_G0277659%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0277619%22%3EDDB_G0277619%3C%2Fa%3E
chr5	1034769	1035879	-	DDB_G0288051	DDB_G0288051	NA
chr5	1036458	1037347	-	DDB_G0288053	empA	NA
chr5	1037957	1038759	-	DDB_G0288063	pspD_ps	putative pseudogene%3B simlar to prespore-specific protein pspD
chr5	1042048	1044305	+	DDB_G0288109	DDB_G0288109	NA
chr5	1045172	1048420	+	DDB_G0288069	DDB_G0288069	NA
chr5	1048762	1050608	-	DDB_G0288071	dst4	putative protein serine%2Fthreonine kinase%3B similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B stress-responsive kinase
chr5	1051212	1057648	-	DDB_G0288073	DDB_G0288073	NA
chr5	1058090	1059280	+	DDB_G0288111	DDB_G0288111	NA
chr5	1059598	1061493	-	DDB_G0288075	DDB_G0288075	NA
chr5	1061950	1062494	+	DDB_G0288113	DDB_G0288113_ps	similar to  a large family of %3Ci%3ED. discoideum%3C%2Fi%3E genes
chr5	1063204	1063374	-	DDB_G0288077	DDB_G0288077_ps	almost identical to a small portion of scy1%2C a protein kinase
chr5	1063770	1065000	-	DDB_G0288079	DDB_G0288079_ps	similar to DDB_G0277993%2C a protein of the importin family
chr5	1065579	1068212	-	DDB_G0288117	wimA_ps1	putative pseudogene%3B similar to the wimA gene%3B contains also a short region of similarity with the forC gene
chr5	1068215	1068657	-	DDB_G0288119	cyp514A1_ps	similar to parts of CYP514A1%2C a cytochrome P450 family protein
chr5	1069064	1073905	+	DDB_G0288121	DDB_G0288121	NA
chr5	1076323	1079112	+	DDB_G0288123	DDB_G0288123	NA
chr5	1079984	1080499	+	DDB_G0288081	DDB_G0288081	NA
chr5	1082632	1083264	-	DDB_G0288087	DDB_G0288087	NA
chr5	1084262	1087093	+	DDB_G0288089	DDB_G0288089	possible homolog of human GCFC (C21orf66)%2C a putative transcription factor
chr5	1087651	1088597	+	DDB_G0288091	DDB_G0288091	conserved hypothetical 277 aa Dictyostelium protein
chr5	1089133	1094480	+	DDB_G0288093	DDB_G0288093	contains a putative N-end rule-based degradation signal%2C which targets a protein for ubiquitin-dependent proteolysis
chr5	1094749	1096458	+	DDB_G0288095	DDB_G0288095	conserved in Dictyostelium and Polysphondylium%3B contains a predicted signal peptide
chr5	1097291	1099021	+	DDB_G0288097	DDB_G0288097	contains a predicted signal peptide
chr5	1099194	1100129	-	DDB_G0288125	DDB_G0288125	NA
chr5	1100340	1101531	-	DDB_G0288099	DDB_G0288099	NA
chr5	1102242	1105954	+	DDB_G0288127	ogdh	component of the 2-oxoglutarate dehydrogenase complex%2C which catalyzes the conversion of 2-oxoglutarate to succinyl-CoA and CO%3Csub%3E2%3C%2Fsub%3E
chr5	1106395	1107007	-	DDB_G0288101	rpl22	protein component of the large (60S) ribosomal subunit
chr5	1107652	1110390	+	DDB_G0288129	DDB_G0288129	NA
chr5	1110992	1116985	+	DDB_G0288103	sibB	integrin beta family protein%3B cytosolic domain binds talin
chr5	1118593	1121222	+	DDB_G0288065	cdcD	CDC48 family AAA ATPase%3B similar to human transitional endoplasmic reticulum ATPase (VCP%2Fp97) and yeast CDC48%3B together with ufd1 and npl4%2C involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation 
chr5	1121891	1123618	+	DDB_G0288105	oxct	catalyzes the reaction succinyl-CoA %2B a 3-oxo acid %3C%3D%3E succinate %2B a 3-oxoacyl-CoA%3B defects in human OXCT1 are a cause of ketoacidosis
chr5	1124020	1125397	+	DDB_G0288107	DDB_G0288107	the protein phosphatase 2C-related domain occurs in protein phosphatase 2C (PPC2) as well as in other proteins%2C such as pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase
chr5	1125741	1130550	+	DDB_G0288067	mf12	similar to a D. purpureum protein
chr5	1130852	1132297	-	DDB_G0288133	DDB_G0288133	mostly similar to proteins in fungi and plants
chr5	1132899	1134443	-	DDB_G0288135	DDB_G0288135	NA
chr5	1134744	1135224	-	DDB_G0304543	psmG4	conserved chaperone protein%2C which promotes assembly of the 20S proteasome%3B may form a dimer with psmG3 and act in concert with psmG1%2FpsmG2
chr5	1135535	1136500	+	DDB_G0288137	DDB_G0288137	NA
chr5	1136855	1137735	+	DDB_G0288139	DDB_G0288139	NA
chr5	1137934	1138329	-	DDB_G0288141	DDB_G0288141	NA
chr5	1139463	1140026	-	DDB_G0288143	DDB_G0288143	similar to lysozyme C proteins from insects%3B contains an additional serine-rich C-terminal region
chr5	1141268	1145420	+	DDB_G0288145	purL	catayzes the reaction ATP %2B 5%27-phosphoribosyl-N-formylglycineamide %2B L-glutamine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E ADP %2B phosphate %2B 5-phosphoribosyl-n-formylglycineamidine %2B L-glutamate in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis
chr5	1147360	1151873	+	DDB_G0288147	pkcA	member of the tyrosine kinase-like (TKL) group%3B similar to plant serine%2Fthreonine kinases%3B contains a phorbol ester%2Fdiacylglycerol (PE%2FDAG)-binding domain
chr5	1152280	1152354	-	DDB_G0295605	sno12	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr5	1152736	1153615	+	DDB_G0288149	DDB_G0288149	has similarity to MADS box transcription enhance factor 2 protein b (MEF2B)
chr5	1154137	1156802	+	DDB_G0288175	DDB_G0288175	NA
chr5	1156915	1158618	-	DDB_G0288151	DDB_G0288151	NA
chr5	1158956	1159536	-	DDB_G0288153	DDB_G0288153	belongs to the thioredoxin family%3B lacks redox-active cysteines compared with many homologs%2C so may be catalytically inactive
chr5	1159975	1160987	-	DDB_G0288155	DDB_G0288155	NA
chr5	1161244	1161975	-	DDB_G0288157	DDB_G0288157	NA
chr5	1162843	1164430	-	DDB_G0288131	cmbB	calmodulin-binding protein comprised of tandem repeats of newly identified IP22 motifs%2C which occur in mimivirus and %3Ci%3EDictyostelium%3C%2Fi%3E%3B IP22 motifs may play a role in cell motility and chemotaxis
chr5	1166139	1166413	+	DDB_G0288159	DDB_G0288159	NA
chr5	1166708	1169551	-	DDB_G0288161	DDB_G0288161	NA
chr5	1170444	1171348	-	DDB_G0288163	arl1	NA
chr5	1172053	1173475	-	DDB_G0288165	DDB_G0288165	sulfurates the molybdenum cofactor%2C which is essential for xanthine dehydrogenase and aldehyde oxidase
chr5	1174416	1174719	+	DDB_G0288167	DDB_G0288167	related to hssA genes
chr5	1175200	1176549	-	DDB_G0288169	cox10	ortholog of COX10%2C which catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity%3B contains seven transmembrane domains
chr5	1177513	1178520	+	DDB_G0288235	DDB_G0288235	NA
chr5	1178682	1179033	-	DDB_G0288185	DDB_G0288185	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon  
chr5	1180046	1181767	-	DDB_G0288187	ddi1	conserved protein that in %3Ci%3ES. cerevisiae%3C%2Fi%3E is a DNA damage-inducible v-SNARE binding protein
chr5	1182370	1183668	+	DDB_G0288189	DDB_G0288189	NA
chr5	1183802	1186027	-	DDB_G0288191	DDB_G0288191	NA
chr5	1186484	1188021	+	DDB_G0288193	DDB_G0288193	NA
chr5	1188181	1193059	-	DDB_G0288237	DDB_G0288237	NA
chr5	1194946	1200961	-	DDB_G0288195	sibC	integrin beta family protein%3B cytosolic domain binds talin%3B expression increases when cells are under conditions that promote adhesiveness
chr5	1202242	1208299	-	DDB_G0288197	sibD	integrin beta family protein%3B cytosolic domain binds talin
chr5	1209765	1215999	-	DDB_G0288239	sibE	integrin beta family protein%3B cytosolic domain binds talin
chr5	1217412	1219101	+	DDB_G0288199	DDB_G0288199_ps	putative pseudogene%3B xpr1 family gene
chr5	1219231	1229553	-	DDB_G0288183	roco9	member of the TKL (tyrosine kinase-like) group and ROCO family of protein kinases%3B contains RhoGAP%2C LRR%2C Roc%2C Cor%2C and protein kinase domains
chr5	1230521	1231854	-	DDB_G0288201	DDB_G0288201	NA
chr5	1233063	1234875	+	DDB_G0288203	DDB_G0288203	amino terminal region is similar to the interferon-related developmental regulator family%3B contains one HEAT repeat%3B similar to D. purpureum protein
chr5	1235608	1237602	+	DDB_G0288205	gacX	NA
chr5	1238068	1240089	+	DDB_G0288181	hspA	involved in phototaxis%2C growth and morphogenesis and implicated in mitochondrial disease
chr5	1240397	1245197	+	DDB_G0288241	DDB_G0288241	NA
chr5	1245352	1245924	-	DDB_G0288207	DDB_G0288207	NA
chr5	1246731	1249049	+	DDB_G0288209	DDB_G0288209	ortholog of mitochondrial twinkle protein%3B involved in mitochondrial DNA (mtDNA) metabolism%3B defects in this gene cause progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 3
chr5	1249148	1250717	-	DDB_G0288211	DDB_G0288211	contains a predicted peroxisomal targeting signal
chr5	1252723	1253950	+	DDB_G0288179	carB	low affinity cAMP receptor%3B belongs to the serpentine%2FG-protein coupled receptor family
chr5	1254786	1255073	-	DDB_G0288213	DDB_G0288213	NA
chr5	1256711	1259715	-	DDB_G0288215	DDB_G0288215	NA
chr5	1259948	1263877	+	DDB_G0288217	mms19	conserved protein that in S. cerevisiae is required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription
chr5	1264761	1267796	+	DDB_G0288231	DDB_G0288231	NA
chr5	1267913	1269691	-	DDB_G0288219	DDB_G0288219	NA
chr5	1270786	1271836	-	DDB_G0288233	DDB_G0288233	NA
chr5	1272181	1273632	+	DDB_G0288221	DDB_G0288221	NA
chr5	1273822	1276819	-	DDB_G0288223	anapc3	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr5	1277134	1278219	+	DDB_G0288225	slbp	binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to histone mRNA 3%27 end processing
chr5	1278382	1279590	-	DDB_G0288243	DDB_G0288243	NA
chr5	1280700	1282179	+	DDB_G0288227	DDB_G0288227	similar to the mammalian SET domain-containing protein 7 (SETD7)%2C a histone methyltransferase that specifically monomethylates Lys-4 of histone H3
chr5	1284583	1289862	+	DDB_G0288251	roco4	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains LRR%2C Roc%2C COR%2C and protein kinase domains
chr5	1290029	1292253	-	DDB_G0288269	fslE	similar to G-protein-coupled receptors%3B weak frizzled cystein-rich domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr5	1292298	1294154	-	DDB_G0288253	fslF	similar to G-protein-coupled receptors%3B weak frizzled cystein-rich domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr5	1294679	1295902	-	DDB_G0288255	DDB_G0288255	very similar to bacterial ribosomal RNA large subunit methyltransferase N%2Calso known as radical SAM protein or Cfr family protein
chr5	1296275	1300079	-	DDB_G0288257	rpb2	component of the RNA polymerase II complex%3B ortholog of S. cerevisiae RPB2
chr5	1300715	1302137	-	DDB_G0288271	DDB_G0288271	methylates the carboxyl group of leucine residues to form alpha-leucine ester residues
chr5	1302980	1305635	+	DDB_G0288259	papA	RNA polymerase that specifically incorporates ATP at the 3%27 end of mRNA
chr5	1306170	1307857	-	DDB_G0288247	aif	involved in caspase-independent mitochondrial cell death%3B similar to H. sapiens AIFM1%2C the mitochondrial Apoptosis-Inducing Factor 1
chr5	1308843	1310648	+	DDB_G0288261	fslG	similar to the G-protein coupled receptors%3B contains 7 putative transmembrane domains and a putative signal peptide
chr5	1310716	1312160	-	DDB_G0288263	DDB_G0288263	NA
chr5	1312496	1313528	-	DDB_G0288273	rpl10	protein component of the large (60S) ribosomal subunit
chr5	1314543	1315018	+	DDB_G0288265	DDB_G0288265	very similar to S. cerevisiae HSP10%2C A. thaliana CPN10%2C and human HSPE1 (HSP10)mitochondrial chaperonins
chr5	1315343	1315783	-	DDB_G0302414	snrpE	conserved SM%2FLSM core protein%2C also known as SME1%3B associates with U1%2C U2%2C U4%2FU6 and U5 snRNP 
chr5	1317088	1319928	+	DDB_G0288245	cigA	induced by cAMP
chr5	1320046	1322570	-	DDB_G0288267	thrS1	catalyzes the reaction ATP %2B L-threonine %2B tRNAThr %3D AMP %2B diphosphate %2B L-threonyl-tRNAThr
chr5	1323200	1327954	-	DDB_G0288249	mkpA	contains a dual specificity protein phosphatase domain and a weak gelsolin domain%3B dual specificity protein phosphatases regulate mitogenic signal transduction and control the cell cycle%3B REMI mutant fails to aggregate%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FmkpA%22%3Ecommunity annotation%3C%2Fa%3E
chr5	1329697	1332090	-	DDB_G0288277	DDB_G0288277	NA
chr5	1332303	1333255	+	DDB_G0288279	DDB_G0288279	NA
chr5	1333499	1334171	-	DDB_G0288309	DDB_G0288309	NA
chr5	1334323	1336548	+	DDB_G0288311	DDB_G0288311	NA
chr5	1336627	1338692	-	DDB_G0349043	DDB_G0349043	NA
chr5	1339549	1340598	-	DDB_G0349042	DDB_G0349042	NA
chr5	1341246	1341541	+	DDB_G0288281	DDB_G0288281	similar to metallothioneins that are involved in the cellular sequestration of toxic metal ions
chr5	1343263	1345372	+	DDB_G0288315	DDB_G0288315	conserved protein%2C contains 8 predicted transmembrane domains and is similar to transmembrane proteins of unknown function in other species
chr5	1345783	1346848	+	DDB_G0288283	DDB_G0288283	NA
chr5	1347341	1352203	-	DDB_G0288285	mybX	contains one Myb DNA-binding domain
chr5	1352566	1353367	-	DDB_G0288287	atg101	similar to human atg101 (autophagy-related protein 101)
chr5	1354074	1355882	+	DDB_G0288289	rliF	very similar to bacterial beta-xylosidases and also but less similar to mammalian alpha-L-iduronidase%3B repressed after %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr5	1356313	1356891	+	DDB_G0288291	DDB_G0288291	contains 1 RRM (RNA recognition motif) domain%3B similar to the RRM domain of eukaryotic peptidyl-prolyl cis-trans isomerase E 
chr5	1357343	1358188	+	DDB_G0288293	DDB_G0288293	conserved protein%2C contains 5 predicted transmembrane domains
chr5	1359447	1360234	+	DDB_G0288295	rpl12	protein component of the large (60S) ribosomal subunit
chr5	1360320	1361741	-	DDB_G0288297	DDB_G0288297	NA
chr5	1361910	1362748	-	DDB_G0288305	pdx2	member of the SNO glutamine amidotransferase family predicted to be involved in the pyridoxine (vitamin B6) biosynthetic pathway%3B catalyzes the deamidation of glutamine as part of the synthesis of pyridoxal 5%27-phosphate%3B the resulting ammonia molecule is channeled to pdxS
chr5	1363519	1364436	+	DDB_G0288299	pdx1	ortholog of S. cerevisiae SNZ1 involved in the pyridoxine (vitamin B6) biosynthetic pathway
chr5	1364968	1369698	+	DDB_G0288301	DDB_G0288301	NA
chr5	1370056	1374931	+	DDB_G0288317	DDB_G0288317	NA
chr5	1375029	1375807	-	DDB_G0288303	DDB_G0288303	NA
chr5	1376942	1381956	-	DDB_G0288307	cnrM	identified as a suppressor of smlA null mutant cnr13
chr5	1385100	1386562	+	DDB_G0288321	dgtA	CAZy family GT2%3B catalyzes the reaction UDP-glucose %2B dolichyl phosphate %3C%3D%3E UDP %2B dolichyl beta-D-glucosyl phosphate
chr5	1387850	1388822	+	DDB_G0288359	dcd3A	catalyzes the reaction N-acylsphingoside %2B H%3Csub%3E2%3C%2Fsub%3EO %3D a carboxylate %2B sphingosine%3B regulated by the MADS-box transcription factor SrfA during development%3Cbr%2F%3E %3Cb%3ENomenclature conflict%3C%2Fb%3E: Do not confuse dcd3A (alkaline dihydroceramidase%2C adcA) with adcA (arrestin domain-containing protein) 
chr5	1389621	1390649	+	DDB_G0288323	strM	conserved in other Dictyostelia%3Cbr%3E %3Cb%3ENomenclature note:%3C%2Fb%3E named by colleagues of M. Satre as the protein sequence starts with MSATRE
chr5	1391586	1393622	+	DDB_G0288363	DDB_G0288363	belongs to the peptidase S8 family%3B contains a predicted signal peptide%3B contains one EGF-like domain
chr5	1394062	1394473	-	DDB_G0288325	DDB_G0288325	conserved uncharacterized transmembrane protein%3B contains 2 predicted transmembrane domains
chr5	1395012	1397601	+	DDB_G0288327	strn	homolog of mammalians striatins%2C calmodulin-binding proteins expressed in the central nervous system%2C and Drosophila Cka%2C involved in the Jun kinase pathway
chr5	1397987	1398640	+	DDB_G0288329	DDB_G0288329	NA
chr5	1399818	1401479	+	DDB_G0288331	expl7	expressed in pstAB cells and in pstAB and stalk cells during the Mexican hat stage and culmination%3B similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B but with a divergent carboxyl terminus%3B contains a predicted signal peptide
chr5	1402047	1403447	+	DDB_G0288333	purB	catalyzes two reactions in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis: 5%27-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole %3C%3D%3E fumarate %2B AICAR and adenylo-succinate %3C%3D%3E fumarate %2B AMP
chr5	1403868	1405272	+	DDB_G0288335	p2xD	member of the Dictyostelium P2X receptor family but ATP-gated ion channel activity could not be demonstrated
chr5	1405893	1408616	-	DDB_G0288339	DDB_G0288339	NA
chr5	1409331	1410610	+	DDB_G0288341	DDB_G0288341	NA
chr5	1410951	1411626	-	DDB_G0288319	arcE	component of the Dictyostelium Arp2%2FArp3 complex
chr5	1412629	1413414	+	DDB_G0288343	DDB_G0288343	NA
chr5	1413915	1415658	+	DDB_G0288345	DDB_G0288345	NA
chr5	1416040	1416327	+	DDB_G0288347	nola3	component of the H%2FACA small nucleolar ribonucleoprotein (H%2FACA snoRNP) complex required for pre-mRNA processing and pseudouridylation
chr5	1416573	1418218	-	DDB_G0288369	DDB_G0288369	NA
chr5	1418812	1419513	-	DDB_G0288349	rpl35	protein component of the large (60S) ribosomal subunit
chr5	1420134	1421792	+	DDB_G0288351	DDB_G0288351	NA
chr5	1422250	1426430	+	DDB_G0288361	kif13	belongs to the BimC%2FEg5 subfamily%2C predicted to play a role in mitosis 
chr5	1426752	1427722	-	DDB_G0288371	DDB_G0288371	weakly similar to S. cerevisiae VPS74%2C a protein of unknown function involved in vacuolar protein sorting
chr5	1428760	1429420	-	DDB_G0288353	DDB_G0288353	NA
chr5	1430508	1433197	+	DDB_G0288355	DDB_G0288355	possible ortholog of THOC5%2C which exists in the THO complex required for transcriptional elongation
chr5	1434151	1434462	+	DDB_G0288357	DDB_G0288357	NA
chr5	1434816	1438681	-	DDB_G0288367	DDB_G0288367	NA
chr5	1439427	1448036	-	DDB_G0294533	roco5	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains RhoGEF%2C PH%2C LRR%2C Roc%2C COR%2C and protein kinase domains
chr5	1450193	1450722	-	DDB_G0295779	DDB_G0295779	NA
chr5	1452516	1453990	+	DDB_G0288375	lis1	dynein regulator associated with centrosomes and microtubules%3B functionally interacts with dcx in cAMP signalling
chr5	1454380	1457655	-	DDB_G0288377	gxcH	NA
chr5	1459573	1460213	-	DDB_G0288379	DDB_G0288379	small cortactin protein%2C a putative actin binding protein%3B conserved in Dictyostelids
chr5	1460823	1462575	-	DDB_G0288381	DDB_G0288381	NA
chr5	1463358	1466756	-	DDB_G0288383	gxcI	NA
chr5	1467682	1468913	-	DDB_G0288385	DDB_G0288385	NA
chr5	1470619	1473138	+	DDB_G0288373	efbA	translocates peptidyl-tRNA from the aminoacyl site to the peptidyl site on the ribosome during protein synthesis%3B null mutants still synthesis protein%2C suggesting that EF-2b (cinC) is the real translation elongation gector
chr5	1473461	1473521	+	DDB_G0295607	r31	small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends%3B localizes to the cytoplasm
chr5	1474122	1480970	-	DDB_G0288387	accA	catalizes the reactions BCCP-biotin-CO%3Csub%3E2%3C%2Fsub%3E %2B acetyl-CoA %2B ATP %3C%3D%3E malonyl-CoA %2B BCCP-biotin %2B phosphate %2B ADP %3Cb%3Eand%3C%2Fb%3E BCCP-biotin %2B CO%3Csub%3E2%3C%2Fsub%3E %2B ATP %3C%3D%3E phosphate %2B ADP %2B BCCP-biotin-CO%3Csub%3E2%3C%2Fsub%3E
chr5	1482942	1484969	-	DDB_G0288447	DDB_G0288447	NA
chr5	1486099	1486735	+	DDB_G0288389	DDB_G0288389	NA
chr5	1486880	1487969	-	DDB_G0288391	snrpB2	ortholog of human SNRPB2%2C a component of the U2 snRNP involved in mRNA splicing%3B also similar to human SNRPA
chr5	1488951	1489589	+	DDB_G0288393	DDB_G0288393	NA
chr5	1489692	1490102	-	DDB_G0288395	DDB_G0288395	NA
chr5	1490397	1490663	-	DDB_G0288397	DDB_G0288397	NA
chr5	1491224	1491445	-	DDB_G0288399	DDB_G0288399	NA
chr5	1492016	1493496	-	DDB_G0288401	prpf38b	contains a conserved PRP38 domain involved in mRNA splicing in yeast
chr5	1494028	1499084	+	DDB_G0288449	rpc2	component of the RNA polymerase III complex%3B ortholog of S. cerevisiae RPC2
chr5	1499232	1500686	-	DDB_G0288403	DDB_G0288403	NA
chr5	1502693	1505171	+	DDB_G0288405	DDB_G0288405	NA
chr5	1505496	1506295	-	DDB_G0288407	DDB_G0288407	NA
chr5	1506576	1509463	+	DDB_G0288411	DDB_G0288411_ps	putative pseudogene%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0288499%22%3EDDB_G0288499%3C%2Fa%3E
chr5	1511045	1511428	-	DDB_G0288417	DDB_G0288417	NA
chr5	1511818	1513272	+	DDB_G0288419	DDB_G0288419	expressed in prespore cells
chr5	1513586	1514830	+	DDB_G0288451	DDB_G0288451_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene  %3Ca href%3D%22%2Fgene%2FDDB_G0288499%22%3EDDB_G0288499%3C%2Fa%3E
chr5	1517413	1517466	-	DDB_G0295609	r58	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr5	1517710	1521638	+	DDB_G0288425	gemin5	ortholog of Gemin 5%2C a component of Cajal bodies (CBs) and Gems%2C nuclear organelles responsible for spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis
chr5	1521809	1525011	-	DDB_G0288453	DDB_G0288453	NA
chr5	1525659	1526462	+	DDB_G0288427	cenA	similar to human Centrin 2 EF-hand protein%3B localizes to the centromer from which it dissociates during mitosis
chr5	1527197	1528361	+	DDB_G0288429	DDB_G0288429	belongs to the short-chain dehydrogenases%2Freductases (SDR) family
chr5	1528754	1529692	+	DDB_G0288433	DDB_G0288433	NA
chr5	1530778	1532414	+	DDB_G0288435	DDB_G0288435	contains 12 putative transmembrane regions
chr5	1532524	1534820	+	DDB_G0288455	DDB_G0288455_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0288437%22%3EDDB_G0288437%3C%2Fa%3E
chr5	1535366	1539274	+	DDB_G0288437	DDB_G0288437	NA
chr5	1539443	1540566	-	DDB_G0288439	syn8B	similar to plant and vertebrate syntaxin 8 involved in vesicle fusion
chr5	1540991	1541919	+	DDB_G0288441	DDB_G0288441	NA
chr5	1542340	1543314	+	DDB_G0288443	DDB_G0288443	NA
chr5	1543867	1551579	+	DDB_G0288457	pks26	putative type I iterative polyketide synthase
chr5	1551650	1556542	-	DDB_G0288459	DDB_G0288459	NA
chr5	1556680	1558176	+	DDB_G0288463	gnt3	CAZy family GT13%3B catalyzes the reaction UDP-N-acetyl-D-glucosamine %2B 3-(a-D-mannosyl)-b-D-mannosyl-R %3C%3D%3E UDP %2B 3-(2-[N-acetyl-b-D-glucosaminyl]-a-D-mannosyl)-b-D-mannosyl-R
chr5	1558211	1559553	-	DDB_G0288465	DDB_G0288465	converts pantetheine 4%27-phosphate to 3%27-dephospho-CoA%3B in other organisms%2C this activity is part of a bifunctional enzyme that also has dephospho-CoA kinase activity%3B in Dictyostelium%2C the latter activity is encoded by %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285525%22%3E%3Ci%3EDDB_G0285525%3C%2Fi%3E%3C%2Fa%3E
chr5	1559882	1560412	-	DDB_G0288467	DDB_G0288467	NA
chr5	1563184	1566066	+	DDB_G0288469	DDB_G0288469	NA
chr5	1566143	1567864	-	DDB_G0288471	taf6	similar to S. cerevisiae TAF6%2C subunit of TFIID and SAGA complexes%2C involved in transcription initiation of RNA polymerase II and in chromatin modification
chr5	1569035	1575345	+	DDB_G0288473	DDB_G0288473	NA
chr5	1575886	1579329	+	DDB_G0288475	DDB_G0288475	similar to comF
chr5	1580012	1581925	-	DDB_G0288477	DDB_G0288477	NA
chr5	1582464	1584009	-	DDB_G0288461	hgsA	catalyzes the reaction acetyl-CoA %2B H2O %2B acetoacetyl-CoA %3D (S)-3-hydroxy-3-methylglutaryl-CoA %2B CoA
chr5	1585841	1586699	-	DDB_G0288479	lsm8	member of a heteromeric complex containing lsm2-8 involved in mRNA splicing
chr5	1587124	1588567	+	DDB_G0294591	DDB_G0294591	contains three putative transmembrane domains%3B not similar to any other protein
chr5	1590688	1591595	-	DDB_G0288505	DDB_G0288505_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr5	1592074	1592146	-	DDB_G0295285	tRNA-Asn-GUU-15	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr5	1594285	1597321	+	DDB_G0288499	DDB_G0288499	NA
chr5	1599423	1600265	+	DDB_G0288489	DDB_G0288489	NA
chr5	1600467	1602368	-	DDB_G0288491	rft1	ortholog of yeast RFT1%2C an essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase 
chr5	1602765	1603564	-	DDB_G0288481	gchA	catalyzes the reaction GTP %2B 2 H%3Csub%3E2%3C%2Fsub%3EO %3D formate %2B 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)-dihydropteridine triphosphate%2C the first step in the biosynthesis of tetrahydropteridines%2C which have been shown to regulate G-protein coupled signalling%3B the gchA gene is expressed and the enzyme is active during the onset of %3Ci%3EDictyostelium%3C%2Fi%3E development
chr5	1604662	1605141	-	DDB_G0288493	DDB_G0288493	NA
chr5	1605485	1607192	+	DDB_G0288495	smdA	similar to human SMYD1%3B putative methyltransferase%3B involved in regulating prespore patterning
chr5	1607944	1611404	+	DDB_G0288501	ddx42	conserved putative RNA helicase%3B very similar to mammalian DDX42
chr5	1611473	1615213	-	DDB_G0288497	DDB_G0288497	NA
chr5	1616073	1619881	+	DDB_G0288485	pikD	subunit of PI4K%2C responsible for the  phosphorylation of phosphatidylinositol (PI) to PI4P (ATP %2B 1-phosphatidyl-1D-myo-inositol %3D ADP %2B 1-phosphatidyl-1D-myo-inositol 4-phosphate)%2C the first committed step in the generation of phosphatidylinositol 4%2C5-bisphosphate (PIP2)%2C a precursor of the second messenger inositol 1%2C4%2C5-trisphosphate (InsP3)
chr5	1620141	1621859	-	DDB_G0288483	pgmA	catalyzes the reaction alpha-D-glucose 1-phosphate %3C%3D%3E alpha-D-glucose 6-phosphate
chr5	1622564	1623654	+	DDB_G0288503	nat2	NA
chr5	1624317	1625307	+	DDB_G0288507	nat3	NA
chr5	1625652	1626671	+	DDB_G0288509	nat1	NA
chr5	1628807	1630997	+	DDB_G0288529	DDB_G0288529	NA
chr5	1631607	1632851	+	DDB_G0288513	DDB_G0288513	NA
chr5	1633091	1633876	+	DDB_G0288515	DDB_G0288515	NA
chr5	1633993	1634951	+	DDB_G0288517	DDB_G0288517	NA
chr5	1635029	1636351	-	DDB_G0288519	DDB_G0288519	NA
chr5	1636790	1638483	+	DDB_G0288521	DDB_G0288521	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr5	1638800	1641837	-	DDB_G0288511	sadA	EGF repeat-containing 9 transmembrane molecule involved in substrate adhesion
chr5	1643762	1644799	+	DDB_G0288523	agpB	belongs to the acyltransferase superfamily
chr5	1644947	1646620	-	DDB_G0288525	DDB_G0288525	NA
chr5	1648133	1649045	-	DDB_G0288539	DDB_G0288539	NA
chr5	1649759	1652129	+	DDB_G0288531	DDB_G0288531	NA
chr5	1652258	1658617	-	DDB_G0288533	macA	NA
chr5	1658897	1660374	-	DDB_G0288541	maoA	catalyzes the reaction RCH%3Csub%3E2%3C%2Fsub%3ENH%3Csub%3E2%3C%2Fsub%3E %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3D RCHO %2B ammonia %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E%3B acts on primary amines%2C as well as on some secondary and tertiary amines
chr5	1660756	1662346	-	DDB_G0288535	DDB_G0288535	NA
chr5	1662584	1665349	-	DDB_G0288537	DDB_G0288537	NA
chr5	1668067	1669008	-	DDB_G0288543	pop4	protein subunit of both the RNase P complex involved in tRNA processing and the RNase MRP complex involved in rRNA processing
chr5	1669968	1676010	+	DDB_G0288545	nup210	similar to nuclear pore membrane glycoprotein 210%3B human NUP210 is essential for nuclear pore assembly%3B contains one putative transmembrane domain and a signal sequence
chr5	1676407	1677541	-	DDB_G0288547	DDB_G0288547	NA
chr5	1677926	1678747	-	DDB_G0288549	DDB_G0288549	conserved protein
chr5	1679413	1681553	+	DDB_G0288551	DDB_G0288551	conserved protein%2C contains 5 PUF domains%3B D. melanogaster pumilio binds through a PUF domain to the 3%27 UTR of target mRNAs
chr5	1681661	1683842	-	DDB_G0288555	DDB_G0288555	NA
chr5	1685010	1686866	+	DDB_G0288559	DDB_G0288559	NA
chr5	1686921	1689320	-	DDB_G0288561	DDB_G0288561_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0278513%22%3EDDB_G0278513%3C%2Fa%3E
chr5	1689437	1690684	-	DDB_G0288563	DDB_G0288563	NA
chr5	1691217	1692747	-	DDB_G0288565	bysl	conserved protein%3B in H. sapiens required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits and possibly for trophinin-dependent regulation of cell adhesion
chr5	1693029	1693641	+	DDB_G0288567	DDB_G0288567	NA
chr5	1693802	1697605	-	DDB_G0288569	DDB_G0288569	NA
chr5	1698545	1699904	+	DDB_G0288571	DDB_G0288571	NA
chr5	1700402	1701204	+	DDB_G0288573	DDB_G0288573	NA
chr5	1706213	1706703	+	DDB_G0288575	DDB_G0288575	NA
chr5	1708038	1708308	+	DDB_G0288605	apl_ps	putative pseudogene%3B fragment%2C similar to the family of saposin domain-containing amoebapore-like proteins
chr5	1709022	1714213	-	DDB_G0288557	vilA	contains seven WD-repeats%2C three PH domains%2C and a villin headpiece%3B is expressed during development and involved in chemotaxis and phototaxis
chr5	1717040	1717198	+	DDB_G0288577	DDB_G0288577	NA
chr5	1717737	1718105	+	DDB_G0288579	DDB_G0288579	NA
chr5	1718254	1719225	-	DDB_G0288581	DDB_G0288581	NA
chr5	1719547	1720254	-	DDB_G0288583	DDB_G0288583	NA
chr5	1720817	1721575	+	DDB_G0288585	DDB_G0288585	NA
chr5	1721620	1722333	-	DDB_G0288587	DDB_G0288587	NA
chr5	1722609	1724610	-	DDB_G0288589	DDB_G0288589	NA
chr5	1725951	1726170	+	DDB_G0288601	DDB_G0288601_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0289787%22%3EDDB_G0289787%3C%2Fa%3E 
chr5	1726934	1728028	+	DDB_G0288591	DDB_G0288591	NA
chr5	1728286	1730370	-	DDB_G0288593	DDB_G0288593	NA
chr5	1730911	1732232	+	DDB_G0288595	DDB_G0288595	NA
chr5	1732418	1734343	-	DDB_G0288597	DDB_G0288597	NA
chr5	1734624	1736547	+	DDB_G0288599	DDB_G0288599	MBOAT family protein%2C membrane proteins that contains a variety of acyltransferase enzymes%3B most similar to S. cerevisiae glycerol uptake protein 1 (GUP1)%3B contains 11 predicted transmembrane domains
chr5	1740020	1741216	-	DDB_G0288609	eral1	NA
chr5	1744822	1745106	+	DDB_G0288615	DDB_G0288615	almost identical to D. purpureum protein
chr5	1745652	1747854	-	DDB_G0288617	shkB	member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily%3B contains a C-terminal SH2 (Src homology 2) domain
chr5	1748711	1749538	-	DDB_G0288619	DDB_G0288619	NA
chr5	1750413	1752480	+	DDB_G0288621	psmD3	contains tetratricopeptide-like helical binding domain
chr5	1753244	1754781	-	DDB_G0288613	erf1	class I release factor of the translation termination machinery%3B in eukaryotes with the universal genetic code%2C predicted to recognizes all stop codons (UAA%2C UAG and UGA)
chr5	1756684	1758646	+	DDB_G0288639	DDB_G0288639	conserved protein%2C DnaJ homolog subfamily C member 7 (DNAJC7)
chr5	1759110	1759748	+	DDB_G0288641	DDB_G0288641	NA
chr5	1759888	1762324	-	DDB_G0288625	DDB_G0288625	NA
chr5	1763068	1764412	+	DDB_G0288627	DDB_G0288627	NA
chr5	1764970	1765761	+	DDB_G0288629	DDB_G0288629	NA
chr5	1766588	1767868	+	DDB_G0288643	DDB_G0288643	NA
chr5	1767936	1770136	-	DDB_G0288631	DDB_G0288631	belongs to the prolyl oligopeptidase family
chr5	1770590	1771346	-	DDB_G0288623	cbpH	NA
chr5	1772020	1773449	+	DDB_G0288637	DDB_G0288637_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0291658%22%3E%3Ci%3EDDB_G0291658%3C%2Fi%3E%3C%2Fa%3E
chr5	1774014	1774917	-	DDB_G0288635	DDB_G0288635	contains a signal peptide and three transmembrane domains
chr5	1776536	1778990	-	DDB_G0288645	DDB_G0288645	NA
chr5	1779747	1781186	-	DDB_G0288647	acad8	ortholog of the %3Ci%3EH. sapiens%3C%2Fi%3E ACAD8 that has very high activity toward isobutyryl-CoA and  might be an isobutyryl-CoA dehydrogenase that functions in valine catabolism
chr5	1782283	1782717	+	DDB_G0288649	ponL	structurally similar to ponticulins%3B contains a putative signal peptide
chr5	1782938	1784507	-	DDB_G0288651	DDB_G0288651	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr5	1786499	1786951	-	DDB_G0288653	DDB_G0288653	NA
chr5	1789768	1790016	-	DDB_G0288657	DDB_G0288657	NA
chr5	1790292	1792082	+	DDB_G0288659	wdr18	ortholog of WDR18
chr5	1792404	1793327	+	DDB_G0288661	DDB_G0288661	NA
chr5	1793780	1794624	+	DDB_G0288663	DDB_G0288663	NA
chr5	1795019	1795722	+	DDB_G0288665	DDB_G0288665	NA
chr5	1796243	1796683	-	DDB_G0288667	DDB_G0288667	NA
chr5	1797088	1798101	-	DDB_G0288669	DDB_G0288669	NA
chr5	1798454	1800291	-	DDB_G0288671	DDB_G0288671	catalyzes the reaction L-proline %2B NAD(P)%3Csup%3E%2B%3C%2Fsup%3E %3C%3D%3E 1-pyrroline-5-carboxylate %2B NAD(P)H %2B H%3Csup%3E%2B%3C%2Fsup%3E
chr5	1800597	1801794	-	DDB_G0288673	DDB_G0288673	NA
chr5	1802347	1808194	-	DDB_G0288655	ugt52	CAZy family GT1%3B catalyzes the reaction UDP-glucose %2B a sterol %3C%3D%3E UDP %2B a glucosylsterol
chr5	1808800	1809275	-	DDB_G0288675	DDB_G0288675	NA
chr5	1810485	1813046	+	DDB_G0288683	DDB_G0288683	NA
chr5	1813615	1816948	+	DDB_G0288685	fam40	NA
chr5	1817419	1819164	+	DDB_G0288687	DDB_G0288687	NA
chr5	1819614	1821695	-	DDB_G0288689	DDB_G0288689	NA
chr5	1822874	1825749	+	DDB_G0288691	hook	similar to C. elegans ZYG-12 and mammalian HOOK proteins%2C which mediates the attachment between the centrosome and the nucleus
chr5	1826054	1827595	-	DDB_G0288739	DDB_G0288739	NA
chr5	1829072	1832587	-	DDB_G0288679	myoE	(unconventional) class I myosin%3B fast motor molecule involved in phagocytosis
chr5	1834141	1836204	+	DDB_G0288693	DDB_G0288693	NA
chr5	1836785	1839502	-	DDB_G0288695	DDB_G0288695	NA
chr5	1839851	1841692	-	DDB_G0288697	DDB_G0288697	NA
chr5	1842289	1843500	-	DDB_G0288699	tmem120	conserved transmembrane protein%3B contains 4 putative transmembrane domains
chr5	1844809	1846008	+	DDB_G0288701	ragA	ortholog of S. cerevisiae GTR1 and H. sapiens RagA and RagB%2C a cytoplasmic GTP binding protein 
chr5	1846430	1846592	+	DDB_G0295611	rnu1c	component of the spliceosome involved in pre-mRNA splicing
chr5	1846726	1848153	-	DDB_G0288703	bud13	ortholog of BUD13%2C which is involved in mRNA splicing in yeast
chr5	1849253	1852183	+	DDB_G0288705	bzpQ	NA
chr5	1852460	1855507	-	DDB_G0288707	DDB_G0288707	NA
chr5	1856022	1858775	-	DDB_G0288709	tgrM2	NA
chr5	1859437	1862153	-	DDB_G0288711	tgrM1	contains a predicted signal peptide
chr5	1863605	1864336	+	DDB_G0288713	DDB_G0288713	NA
chr5	1864937	1865623	+	DDB_G0288737	DDB_G0288737	NA
chr5	1865900	1867387	+	DDB_G0288715	gadB	catalyzes the reaction L-glutamate %3D 4-aminobutanoate %2B CO%3Csub%3E2%3C%2Fsub%3E%3B expressed in vegetative cells
chr5	1867636	1869387	-	DDB_G0288717	DDB_G0288717	NA
chr5	1870152	1870314	-	DDB_G0295613	rnu1d	component of the spliceosome involved in pre-mRNA splicing
chr5	1870694	1873130	-	DDB_G0288719	scfd1	ortholog of H. sapiens SCFD1 and S. cerevisiae SLY1
chr5	1873609	1875087	+	DDB_G0288681	prpD	similar to Salmonella typhimurium PrpD protein
chr5	1876627	1876797	+	DDB_G0288721	prpD_ps	putative pseudogene%3B small fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0288681%22%3E%3Ci%3EprpD%3C%2Fi%3E%3C%2Fa%3E 
chr5	1876927	1878113	-	DDB_G0288723	DDB_G0288723	highly conserved protein
chr5	1879264	1882869	-	DDB_G0288725	DDB_G0288725	NA
chr5	1883551	1884195	+	DDB_G0288727	DDB_G0288727	NA
chr5	1885785	1886770	+	DDB_G0288677	cdk5	CMGC group protein kinase%2C highly similar to mammalian cdk5%3B localizes to the nucleus and shuttles to the cytoplasm during late mitosis%3B binds calmodulin%2C PsaA
chr5	1887042	1888100	-	DDB_G0288729	DDB_G0288729	ortholog of the mammalian reticulon-4-interacting protein 1%2C a zinc-containing alcohol dehydrogenase
chr5	1888714	1892397	+	DDB_G0288731	DDB_G0288731	highly similar to mammalian myotubularin-related protein 2 in sequence and in domain architecture%2C a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3%2C5)-bi-phosphate
chr5	1892916	1893557	+	DDB_G0288745	DDB_G0288745	expressed in prespore cells
chr5	1894171	1894596	+	DDB_G0288733	DDB_G0288733_ps	putative pseudogene%3B similar to a family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0268734%22%3EDDB_G0268734%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0277457%22%3EDDB_G0277457%3C%2Fa%3E
chr5	1895573	1897531	+	DDB_G0288735	DDB_G0288735	very similar to acyl-coenzyme A oxidases%2C but lacks the full domain
chr5	1903969	1908946	+	DDB_G0288751	DDB_G0288751	NA
chr5	1909293	1911862	-	DDB_G0288753	ndrB	member of the AGC kinase group%3B similar to NDR protein kinases%2C including yeast morphogenesis proteins ORB6 and CBK1
chr5	1912921	1916049	+	DDB_G0288747	DDB_G0288747	contains one Myb DNA-binding domain%3B similar to D. rerio DNA methyltransferase 1 associated protein 1
chr5	1916080	1917777	-	DDB_G0288749	abkA	atypical protein serine%2Fthreonine kinase%2C contains ABC1 kinase (protein kinase-like) domain%3B yeast ABC1 essential for the electron transfer in the BC(1) complex%3B E.coli homolog required for ubiquinone biosynthesis
chr5	1923643	1925769	+	DDB_G0288755	gbfA	transcription factor required for expression of post-aggregation genes
chr5	1926304	1926959	-	DDB_G0288757	DDB_G0288757	catalyzes the reaction ATP %2B nicotinamide ribonucleotide %3D diphosphate %2B NAD%2B
chr5	1927278	1927406	-	DDB_G0288761	DDB_G0288761	NA
chr5	1928245	1930320	+	DDB_G0295735	DDB_G0295735	contains four predicted transmembrane domains
chr5	1930552	1931149	-	DDB_G0288759	tmem14A	one of two Dictyostelium proteins in the eukaryotic transmembrane protein 14 (TMEM14) family%3B contains four putative transmembrane domains
chr5	1933766	1934884	+	DDB_G0288763	DDB_G0288763	NA
chr5	1935972	1936502	+	DDB_G0288765	DDB_G0288765	NA
chr5	1936647	1937305	+	DDB_G0288767	DDB_G0288767	NA
chr5	1938769	1939117	-	DDB_G0288775	mppB_ps	putative pseudogene%3B fragment%2C very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0288777%22%3EmppB%3C%2Fa%3E
chr5	1942737	1944721	-	DDB_G0288777	mppB	removes the transit peptide from the precursor form of proteins imported from the cytoplasm across the mitochondrial inner membrane%3B consists of an alpha (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274809%22%3E%3Ci%3EmppA%3C%2Fi%3E%3C%2Fa%3E) and a beta subunit
chr5	1946096	1947490	+	DDB_G0288769	cap	component of the endo-lysosomal system%2C links with actin cytoskeleton %3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with capA%2C the cAMP-binding protein
chr5	1950277	1951758	+	DDB_G0288779	DDB_G0288779	NA
chr5	1951922	1953292	-	DDB_G0288781	DDB_G0288781	NA
chr5	1954614	1956782	+	DDB_G0288861	DDB_G0288861	large molecular weight protein that contains a hsp20 domain 
chr5	1956943	1958527	-	DDB_G0288863	agpC	belongs to the acyltransferase superfamily
chr5	1959111	1959596	-	DDB_G0288865	DDB_G0288865	NA
chr5	1962158	1963568	+	DDB_G0288783	mybG	contains one Myb DNA-binding domain
chr5	1964055	1964845	+	DDB_G0288785	cbpL	putative Ca2%2B-binding protein with 4 putative EF-hands%3B belongs to the frequenins%2C a family of myristoyl-switch calcium-binding proteins
chr5	1965193	1966338	-	DDB_G0288787	vps29	ortholog of VPS29%2C a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport
chr5	1967179	1968306	+	DDB_G0288789	hlcs2	functions in post-translational modification of various carboxylases by attachment of biotin%3B similar to human HLCS%2C which when defect causes a neonatal form of multiple carboxylase deficiency%3B %3Ci%3EDictytostelium%3C%2Fi%3E contains three similar enzymes%2C %3Ca href%3D%22%2Fgene%2FDDB_G0288791%22%3Ehlcs1%3Ca%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0288789%22%3Ehlcs2%3Ca%3E%2C and %3Ca href%3D%22%2Fgene%2FDDB_G0289035%22%3Ehlcs3%3Ca%3E
chr5	1968883	1970010	+	DDB_G0288791	hlcs1	functions in post-translational modification of various carboxylases by attachment of biotin%3B similar to human HLCS%2C which when defect causes a neonatal form of multiple carboxylase deficiency%3B %3Ci%3EDictytostelium%3C%2Fi%3E contains three similar enzymes%2C %3Ca href%3D%22%2Fgene%2FDDB_G0288791%22%3Ehlcs1%3Ca%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0288789%22%3Ehlcs2%3Ca%3E%2C and %3Ca href%3D%22%2Fgene%2FDDB_G0289035%22%3Ehlcs3%3Ca%3E
chr5	1970396	1973239	-	DDB_G0288867	DDB_G0288867	NA
chr5	1973649	1975169	-	DDB_G0288793	DDB_G0288793	NA
chr5	1975761	1977992	-	DDB_G0288795	DDB_G0288795	putative protein serine%2Fthreonine kinase%2C AGC group%3B similar to the kinase domains of mammalian AKT%2FPKB%3B similar to yeast protein kinases GAD8 and SCH9
chr5	1979163	1980936	+	DDB_G0288797	fip1l1	ortholog of yeast FIP1 and mmamalian FIP1L%2C  component of the cleavage and polyadenylation specificity factor (CPSF) complex required for 3%27 processing of mRNAs%3B directly interacts with poly(A) polymerase
chr5	1981150	1981668	-	DDB_G0288799	mrpl21	protein component of the mitochondrial large ribosomal subunit
chr5	1982434	1984703	-	DDB_G0288801	scdA	contains a cytochrome b5 domain%3B introduces a double bond at the delta position of fatty acids during the biosynthesis of monounsaturated fatty acids
chr5	1985593	1989745	+	DDB_G0288803	irlE	putative protein serine%2Fthreonine kinase%3B the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy
chr5	1989890	1989962	+	DDB_G0295237	tRNA-Gln-UUG-12	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr5	1990254	1994153	+	DDB_G0288805	DDB_G0288805	NA
chr5	1994269	1997019	-	DDB_G0288771	darA	putative ortholog of the mammalian guanine nucleotide exchange factor smgGDS%2C a GEF that acts on a broad spectrum of small GTPases (rap1%2C rac1%2C cdc42)%3B in Dictyostelium%2C darlin contains 11 armadillo-like repeats%3B it binds to racE and racC%2C but the GEF activity could not be detected using racE as a substrate%3B the darA null mutant is aggregation defective when developed in buffer%2C but the development is normal in the presence of bacteria
chr5	1997456	1998557	-	DDB_G0288807	ppt2	very similar to human PPT2%2C an enzyme which catalyzes the reaction: palmitoyl-protein %2B H%3Csub%3E2%3C%2Fsub%3EO %3D palmitate %2B protein
chr5	2000009	2003459	+	DDB_G0288859	jcdJ	NA
chr5	2003648	2005462	-	DDB_G0288773	ncfA	homolog of the essential mammalian neutrophil cytosolic factor p67 that functions as an NADPH oxidase activator%3B contains N-terminal TPR repeats and a C-terminal WW domain
chr5	2006806	2009608	+	DDB_G0288811	DDB_G0288811	very similar to TBC1 domain family member 15 proteins and yeast GYP7%3B TBC domain-containing proteins in yeast are GTPase activator proteins
chr5	2010767	2015650	+	DDB_G0288813	DDB_G0288813	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr5	2016292	2021047	+	DDB_G0288815	DDB_G0288815	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr5	2021392	2025051	+	DDB_G0288869	DDB_G0288869	contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one extracellular EGF-2 domain
chr5	2025270	2027079	-	DDB_G0288817	osbK	NA
chr5	2028467	2033022	-	DDB_G0288819	ncapG2	component of the condensin II complex%2C which is involved in physical rigidity of the chromatid axis
chr5	2033361	2034446	-	DDB_G0288821	DDB_G0288821	NA
chr5	2035104	2035785	+	DDB_G0288823	lzic	conserved protein
chr5	2036092	2039207	-	DDB_G0288825	DDB_G0288825	NA
chr5	2040745	2043732	+	DDB_G0288827	DDB_G0288827	NA
chr5	2043960	2044475	-	DDB_G0288829	DDB_G0288829	NA
chr5	2045007	2045189	-	DDB_G0288831	cox17	NA
chr5	2045678	2046507	-	DDB_G0288833	derl1	component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins%3B contains 5 putative transmembrane domains
chr5	2047432	2048948	+	DDB_G0288835	prfB	required for the termination of protein biosynthesis%3B class I release factors bind to ribosomes that have encountered a stop codon at their decoding site and induce release of the nascent polypeptide%3B mediates UAA and UGA-dependent termination in prokaryotes
chr5	2049688	2052061	+	DDB_G0288839	tmc_ps2	putative pseudogene%3B similar to a gene family in Dictyostelium%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289207%22%3EtmcB%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0289253%22%3EtmcC%3C%2Fa%3E
chr5	2053563	2053863	+	DDB_G0288841	DDB_G0288841	related to the hssA genes
chr5	2054056	2055509	+	DDB_G0288843	tmc_ps3	putative pseudogene%3B similar to a gene family in Dictyostelium%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289207%22%3EtmcB%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0289253%22%3EtmcC%3C%2Fa%3E
chr5	2055893	2056960	-	DDB_G0288847	DDB_G0288847	NA
chr5	2057527	2059502	-	DDB_G0288849	DDB_G0288849	contains a predicted signal peptide and a putative C-terminal transmembrane domain%3B similar to S. cerevisiae ERO1 (endoplasmic oxidoreductin-1) which is required for the formation of disulfide bonds in the proteins in the endoplasmic reticulum
chr5	2060041	2060472	+	DDB_G0288851	DDB_G0288851	NA
chr5	2060725	2060964	-	DDB_G0288871	DDB_G0288871	NA
chr5	2063858	2065333	+	DDB_G0288853	DDB_G0288853	NA
chr5	2065550	2070113	-	DDB_G0288873	pich	ortholog of human DNA excision repair protein ERCC-6-like (ERCC6L)%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0288873%2C but not ercc6%2C is strongly overexpressed (6x) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted.  Most cells involved in S-phase or mitosis are overexpressed in this strain. Ercc6-like is an essential component of the spindle checkpoint%2C which localizes to the kinetochore%3B in prometaphase it is found on thin threads that stretch between sister kinetochores.  It is thought to function as part of the tension sensor%2C the functional core of the spindle checkpoint [see Baumann et al%2C Cell 128%2C 101-114 (2007)]. Other spindle checkpoint components are strongly overexpressed in the rblA null. This suggests that DDB_G0288873 may actually code for the spindle tension sensor in Dicty. %3Ci%3EHarry MacWilliams%2C May 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Fpich%22%3E There is more information on the wiki page%3C%2Fa%3E
chr5	2077569	2080523	+	DDB_G0288951	DDB_G0288951	NA
chr5	2080789	2082234	-	DDB_G0288953	DDB_G0288953	NA
chr5	2082521	2083101	+	DDB_G0288881	nmd3_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271306%22%3E%3Ci%3Enmd3%3C%2Fi%3E%3C%2Fa%3E
chr5	2083221	2083670	-	DDB_G0288883	DDB_G0288883	NA
chr5	2083996	2085193	+	DDB_G0288885	DDB_G0288885	NA
chr5	2086198	2086420	-	DDB_G0288887	DDB_G0288887	NA
chr5	2086808	2088244	-	DDB_G0288889	DDB_G0288889	NA
chr5	2088484	2089755	-	DDB_G0288891	hemH	catalyzes the reaction protoporphyrin %2B Fe%3Csup%3E2%2B%3C%2Fsup%3E %3D protoheme %2B 2 H%3Csup%3E%2B%3C%2Fsup%3E in heme biosynthesis
chr5	2090427	2091425	+	DDB_G0288893	hemF	catalyzes the reaction coproporphyrinogen-III %2B O%3Csub%3E2%3C%2Fsub%3E %2B 2 H%2B %3D protoporphyrinogen-IX %2B 2 CO%3Csub%3E2%3C%2Fsub%3E %2B 2 H%3Csub%3E2%3C%2Fsub%3EO
chr5	2091691	2093291	-	DDB_G0288895	DDB_G0288895	contains one BAR (BIN%2FAmphiphysin%2FRvs) domain and SH3 domain
chr5	2093655	2094704	-	DDB_G0288897	DDB_G0288897	NA
chr5	2094858	2096650	+	DDB_G0288899	pigM	CAZy family GT50%3B catalyzes the addition of the first mannose to GPI (glycosylphosphatidylinositol)
chr5	2096747	2100450	-	DDB_G0288955	DDB_G0288955	contains multiple EGF-like domains%3B contains contains a predicted signal sequece%2C and a putative transmembrane domain
chr5	2101452	2103285	-	DDB_G0288949	DDB_G0288949	NA
chr5	2103495	2105057	+	DDB_G0288901	DDB_G0288901	NA
chr5	2105412	2105816	+	DDB_G0288903	cox19	NA
chr5	2106066	2107862	-	DDB_G0288905	DDB_G0288905	NA
chr5	2108749	2109813	+	DDB_G0288907	smtA	NA
chr5	2110038	2111898	+	DDB_G0288909	pus3	similar to S. cerevisiae pus3%2C which introduces pseudouridines at position 38 or 39 in tRNA
chr5	2112807	2113412	+	DDB_G0288911	DDB_G0288911	contains a predicted signal sequence%3B similar to a D. purpureum protein
chr5	2113860	2114407	+	DDB_G0288913	DDB_G0288913	NA
chr5	2114788	2118427	-	DDB_G0288915	DDB_G0288915	NA
chr5	2119308	2120353	+	DDB_G0288917	DDB_G0288917	similar to retinol dehydrogenase and eukaryotic proteins of the short chain dehydrogenases%2Freductases family
chr5	2120577	2123203	-	DDB_G0288919	psiI	contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 6 Dictyostelium (CTDC) repeats and a C-terminal transmembrane domain
chr5	2124478	2125149	-	DDB_G0288921	hspI	NA
chr5	2127210	2129497	+	DDB_G0288875	ndufv1	ortholog of the mammalian NDUFV1 (NADH dehydrogenase ubiquinone flavoprotein 1) that transfers electrons from NADH to the respiratory chain
chr5	2130048	2134208	+	DDB_G0288923	upf1	ortholog of yeast NAM7 and the mammalian UPF1 (up-frameshift suppressor 1) or RENT1 protein%2C part of a post-splicing multiprotein complex and involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons
chr5	2134650	2135356	-	DDB_G0288925	DDB_G0288925	NA
chr5	2135701	2137186	+	DDB_G0288929	DDB_G0288929	NA
chr5	2137477	2138366	+	DDB_G0288931	DDB_G0288931	NA
chr5	2140408	2142715	+	DDB_G0288957	DDB_G0288957	NA
chr5	2143283	2144539	-	DDB_G0288959	DDB_G0288959	NA
chr5	2144804	2145603	-	DDB_G0288933	cda	catalyzes the reactions cytidine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E uridine %2B NH%3Csub%3E3%3C%2Fsub%3E and H%3Csub%3E2%3C%2Fsub%3EO %2B deoxycytidine %3C%3D%3E NH%3Csub%3E3%3C%2Fsub%3E %2B deoxyuridine
chr5	2146739	2148344	+	DDB_G0288961	eif2b1	NA
chr5	2148704	2149606	+	DDB_G0288935	panC	catalyzes the reaction ATP %2B (R)-pantoate %2B beta-alanine %3D AMP %2B diphosphate %2B (R)-pantothenate
chr5	2149735	2151215	-	DDB_G0288937	arpA	centrosome-associated actin homolog%2C contributes to the dynactin complex%3B contributes to DdPPK2 activity%2C also described as member of the polyphosphate kinase PPK3 family
chr5	2152189	2155430	+	DDB_G0288939	valS2	catalyzes the reaction ATP %2B L-valine %2B tRNAVal %3D AMP %2B diphosphate %2B L-valyl-tRNAVal
chr5	2155528	2158010	-	DDB_G0288963	DDB_G0288963	similar to the conserved metallocarboxypeptidase D (CPD)%2C a membrane bound protein%3B the %3Ci%3EDictyostelium%3C%2Fi%3E protein is shorter and has only one M14 peptidase domain versus three such domains in the animal proteins%2C and also does not seem to contain a transmembrane domain
chr5	2158460	2159002	+	DDB_G0288941	DDB_G0288941	NA
chr5	2159616	2160638	+	DDB_G0288943	DDB_G0288943	NA
chr5	2161054	2161432	-	DDB_G0288945	DDB_G0288945	NA
chr5	2162285	2166798	+	DDB_G0288947	DDB_G0288947	similar to Entamoeba histolytica viral A-type inclusion repeat-containing protein
chr5	2167534	2168664	+	DDB_G0288879	act11	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr5	2168858	2171217	-	DDB_G0288877	aarA	component of actin-associated intercellular junctions and involved in cell-cell adhesion%2C signal transduction%2C and stalk formation during development%3B binds to Ctnna%2C the Dictyostelium alpha-catenin related protein
chr5	2174329	2176481	-	DDB_G0288965	DDB_G0288965	NA
chr5	2179762	2182568	+	DDB_G0288967	DDB_G0288967	NA
chr5	2182982	2186089	+	DDB_G0288969	DDB_G0288969	NA
chr5	2186215	2186653	-	DDB_G0288971	DDB_G0288971	NA
chr5	2186905	2188408	+	DDB_G0288973	DDB_G0288973	NA
chr5	2192060	2197136	+	DDB_G0288975	hbx13	NA
chr5	2198403	2201058	+	DDB_G0288977	iqgC	contains a rasGAP domain%3B similar to mammalian IQGAP proteins but lacking the calponin domain and the IQ-calmodulin binding region
chr5	2201638	2203235	+	DDB_G0288979	trmu	catalyzes the reaction: S-adenosyl-L-methionine %2B tRNA %3D S-adenosyl-L-homocysteine %2B tRNA containing 5-methylaminomethyl-2-thiouridylate
chr5	2203346	2203786	-	DDB_G0288981	DDB_G0288981	NA
chr5	2204231	2205372	-	DDB_G0288983	mrpl3	protein component of the mitochondrial large ribosomal subunit
chr5	2206145	2206765	+	DDB_G0288985	purN	catalyzes the reaction N10-formyl-H%3Csub%3E4%3C%2Fsub%3EF %2B 5-phospho-ribosyl-glycineamide %3C%3D%3E tetrahydrofolate %2B 5%27-phosphoribosyl-N-formylglycineamide in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis
chr5	2206848	2208977	-	DDB_G0288987	DDB_G0288987	NA
chr5	2209540	2210312	+	DDB_G0288989	nipsnap	conserved protein that may have a role in vesicle transport
chr5	2210519	2211097	-	DDB_G0288991	DDB_G0288991	NA
chr5	2211609	2215371	-	DDB_G0288993	smc6	functions in chromosome dynamics%3B heterodimerizes with smc5
chr5	2215599	2216529	+	DDB_G0288997	DDB_G0288997	NA
chr5	2216611	2217089	-	DDB_G0288999	DDB_G0288999_ps	putative pseudogene%3B highly conserved family containing an alkyl hydroperoxide reductase%2Fthiol specific antioxidant%2Fmal allergen domain
chr5	2223594	2224986	+	DDB_G0289007	DDB_G0289007	NA
chr5	2225715	2226422	-	DDB_G0289009	DDB_G0289009	NA
chr5	2226660	2227191	-	DDB_G0289011	DDB_G0289011	similar to human C20orf24 (Rab5-interacting protein)%3B contains 2 putative transmembrane domains
chr5	2227887	2229274	+	DDB_G0289003	psmC4	ATPase subunit and regulatory subcomplex of the 26S proteasome%3B developmentally regulated TAT binding protein homolog
chr5	2230553	2232648	+	DDB_G0289013	slc44a2	NA
chr5	2232832	2233857	-	DDB_G0289015	DDB_G0289015	NA
chr5	2234318	2235448	-	DDB_G0289005	act4	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)   
chr5	2236776	2240954	-	DDB_G0289017	DDB_G0289017	NA
chr5	2243747	2246494	-	DDB_G0289019	DDB_G0289019	NA
chr5	2249624	2249721	-	DDB_G0295615	sno7	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr5	2250572	2251309	+	DDB_G0289021	ube2s	NA
chr5	2251614	2252834	+	DDB_G0289023	DDB_G0289023	NA
chr5	2252902	2253483	-	DDB_G0289025	rps7	protein component of the small (40S) ribosomal subunit
chr5	2254543	2255591	-	DDB_G0289027	DDB_G0289027	NA
chr5	2256321	2257763	-	DDB_G0289029	DDB_G0289029	conserved protein%2C similar to  S. cerevisiae IST1 (Increased Sodium Tolerance) that plays a role in the endosome to vacuole transport via the multivesicular body sorting pathway%3B contains an N-terminal DUF292 domain
chr5	2258354	2259643	-	DDB_G0289031	DDB_G0289031	ortholog of the conserved spastic paraplegia 21 (SPG21) also known as Maspardin%3B defects in human SPG21 are the cause of the neurodegenerative disorder spastic paraplegia also known as Mast syndrome
chr5	2260286	2266127	+	DDB_G0289049	DDB_G0289049_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr5	2265374	2265446	+	DDB_G0295239	tRNA-Ala-AGC-9	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr5	2269413	2273543	-	DDB_G0289001	pyk3	member of the TKL (tyrosine kinase-like) group and the DPYK (Dictyostelium protein tyrosine kinase) family of protein kinases%3B contains two kinase domains%2C one of which is predicted to be inactive%3B the C-terminal kinase domain has tyrosine kinase activity%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Pyk3 appears to be involved in differentiation pathway choice%2C as the KO shows reduced pstO differentiation and compensatory expansion of the prespore region. Pyk3 has been proposed to act in a pathway involving ptpC and statC effectively potentiating the action of DIF-1. One of the factors that influences pathway choice is cell cycle position%3B classic experiments show that cold-synchronized cells which enter development shortly after warming prefer the stalk pathway. This is due to an increased DIF sensitivity. New results (Strasser%2C Tsang and MacWilliams%2C in preparation) now show that the pyk3 transcript is upregulated roughly fivefold after cold synchronization%2C at a time when cells show strong stalk preference (p for the null hypothesis%3CE-292). Pyk3 and interactors may thus be part of a pathway responsible for the cell-cycle dependence of differentiation pathway choice.  %3Ci%3EHarry MacWilliams%2C  August 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2Fpyk3%22%3E There is more information on the wiki page%3C%2Fa%3E
chr5	2275554	2277122	+	DDB_G0289051	DDB_G0289051	NA
chr5	2277325	2282094	-	DDB_G0289033	DDB_G0289033	contains a GAS2 (growth-arrest-specific protein 2) domain which is often found associated with the CH (calponin homology) domain%3B putative actin binding protein
chr5	2283370	2284584	+	DDB_G0289035	hlcs3	functions in post-translational modification of various carboxylases by attachment of biotin%3B similar to human HLCS%2C which when defect causes a neonatal form of multiple carboxylase deficiency%3B %3Ci%3EDictytostelium%3C%2Fi%3E contains three similar enzymes%2C %3Ca href%3D%22%2Fgene%2FDDB_G0288791%22%3Ehlcs1%3Ca%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0288789%22%3Ehlcs2%3Ca%3E%2C and %3Ca href%3D%22%2Fgene%2FDDB_G0289035%22%3Ehlcs3%3Ca%3E
chr5	2284637	2285502	-	DDB_G0289037	ufc1	NA
chr5	2286110	2287552	+	DDB_G0289039	DDB_G0289039	NA
chr5	2287957	2290485	+	DDB_G0289041	DDB_G0289041	NA
chr5	2291494	2297048	+	DDB_G0289043	DDB_G0289043	NA
chr5	2297386	2298311	-	DDB_G0289045	DDB_G0289045	NA
chr5	2299492	2302095	-	DDB_G0289047	DDB_G0289047	highly similar to bacterial ClpB%3B expressed in prespore cells
chr5	2302813	2304352	-	DDB_G0289053	DDB_G0289053	similar to mammalian RNPS1 (RNA-binding protein with serine-rich domain 1)%2C part of pre- and post-splicing multiprotein mRNP complexes
chr5	2306273	2307050	+	DDB_G0289069	arrD	NA
chr5	2307545	2308570	+	DDB_G0289057	DDB_G0289057	NA
chr5	2308883	2310046	+	DDB_G0289059	DDB_G0289059	NA
chr5	2310384	2311522	+	DDB_G0289061	DDB_G0289061	NA
chr5	2312279	2313391	+	DDB_G0289063	DDB_G0289063	NA
chr5	2314833	2315321	+	DDB_G0289065	DDB_G0289065	similar to yeast ERG28%2C an endoplasmic reticulum protein involved in ergosterol biosynthesis%3B contains 4 putative transmembrane domains
chr5	2315722	2319653	-	DDB_G0289067	smkA	suppressor of %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269152%22%3E%3Ci%3EmekA%3C%2Fi%3E%3C%2Fa%3E (mek1) nulll mutant%3B translocates from cell cortex to the nucleus during starvation
chr5	2321011	2321083	+	DDB_G0295241	tRNA-Asn-GUU-14	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr5	2321624	2322081	+	DDB_G0289071	DDB_G0289071_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr5	2322480	2324270	+	DDB_G0289107	DDB_G0289107_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr5	2325208	2326112	-	DDB_G0289109	DDB_G0289109	NA
chr5	2326670	2330018	-	DDB_G0289077	DDB_G0289077	NA
chr5	2330339	2331579	+	DDB_G0289079	mnat1	conserved RING finger protein that stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex
chr5	2331738	2335669	-	DDB_G0289081	DDB_G0289081	contains a NAD(P)-binding domain%3B contains a predicted peroxisomal targeting signal
chr5	2336464	2336850	-	DDB_G0289083	drpp20_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0289139%22%3E%3Ci%3Edrpp20%3C%2Fi%3E%3C%2Fa%3E 
chr5	2337171	2339014	+	DDB_G0289085	mmsdh	catalyzes the reaction 2-methyl-3-oxopropanoate %2B CoA %2B NAD%2B %3C%3D%3E propanoyl-CoA %2B CO%3Csub%3E2%3C%2Fsub%3E %2B NADH %2B H%3Csup%3E%2B%3C%2Fsup%3E
chr5	2339443	2339664	-	DDB_G0289089	DDB_G0289089	NA
chr5	2340065	2342458	-	DDB_G0289091	DDB_G0289091	NA
chr5	2342795	2344339	-	DDB_G0289073	csaA	an EDTA stable cell-cell adhesion protein%2C a fast-acting adhesion that is important in aggregation and development under natural conditions (soil)
chr5	2345850	2347224	+	DDB_G0289093	DDB_G0289093	NA
chr5	2348039	2349715	+	DDB_G0289095	DDB_G0289095	NA
chr5	2349881	2351452	-	DDB_G0289097	DDB_G0289097	NA
chr5	2352021	2352950	-	DDB_G0289075	spiA	regulated by the MADS-box transcription factor SrfA during development%3B expressed in prespore cells
chr5	2353928	2354869	+	DDB_G0289111	DDB_G0289111	NA
chr5	2356325	2358751	+	DDB_G0289099	DDB_G0289099	contains an N-terminal F-box domain
chr5	2361177	2361437	+	DDB_G0289101	DDB_G0289101	NA
chr5	2361958	2368217	+	DDB_G0289105	tpc2	similar to human TPC2%2C a two-pore calcium channel%3B contains Ca2%2B-binding EF-hands and 2 x 5 (10 total) putative transmembrane domains
chr5	2368291	2369018	-	DDB_G0289103	racM	NA
chr5	2369676	2373767	+	DDB_G0289113	DDB_G0289113	NA
chr5	2375954	2378600	+	DDB_G0289115	mhkB	myosin heavy chain kinase%2C an atypical protein serine%2Fthreonine kinase in the Alpha kinase group%3B participates in the regulation of myosin II assembly into the cytoskeleton
chr5	2378873	2383894	-	DDB_G0289123	DDB_G0289123	NA
chr5	2384391	2385238	+	DDB_G0289125	DDB_G0289125	NA
chr5	2385358	2386395	-	DDB_G0289127	DDB_G0289127	NA
chr5	2386701	2387669	-	DDB_G0289129	DDB_G0289129	NA
chr5	2388498	2389598	+	DDB_G0289131	DDB_G0289131	NA
chr5	2389784	2391124	-	DDB_G0289133	DDB_G0289133	NA
chr5	2391473	2392738	+	DDB_G0289135	bcs1lA	conserved mitochondrial chaperone necessary for the assembly of mitochondrial respiratory chain complex III%3B %3Ci%3E Dictyostelium%3C%2Fi%3E has a second BCS1-like protein%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0291910%22%3E%3Ci%3Ebcs1lB%3C%2Fi%3E%3C%2Fa%3E
chr5	2392822	2393223	-	DDB_G0289137	DDB_G0289137	NA
chr5	2393417	2394447	+	DDB_G0289139	drpp20	protein subunit of both the RNase P complex involved in tRNA processing and the RNase MRP complex involved in rRNA processing
chr5	2395095	2400678	+	DDB_G0289141	DDB_G0289141	NA
chr5	2402421	2406561	+	DDB_G0289121	pde4	a membrane bound cAMP phosphodiesterase with an extracellular catalytic domain regulating cAMP catabolism during development
chr5	2407681	2409472	+	DDB_G0289143	DDB_G0289143	contains 11 putative transmembrane domains%3B similar to D. purpureum protein
chr5	2410248	2413925	+	DDB_G0289117	myoB	long tailed class-1 myosin%2C a molecular motor protein that localizes to actin-rich structures at the leading edge of migrating cells
chr5	2414259	2415536	-	DDB_G0289145	pde7	NA
chr5	2417343	2418146	-	DDB_G0289147	DDB_G0289147	belongs to the crotonase superfamily
chr5	2419396	2420128	+	DDB_G0289149	litaf	%3Ci%3ED. dicoideum%3C%2Fi%3E ortholog of the conserved lipopolysaccharide-induced tumor necrosis factor alpha factor (LITAF)%2C induced in mamalian cells following treatment with lipopolysaccharide%2C a small integral membrane protein of lysosome%2Flate endosome%3B contains one predicted transmembrane domain
chr5	2420542	2422700	-	DDB_G0289119	pXi	CAMK group protein serine%2Fthreonine kinase
chr5	2425624	2428557	-	DDB_G0289151	mybI	contains one myb DNA-binding domain
chr5	2432359	2434043	+	DDB_G0289157	cmfB	putative receptor mediating cell-density sensing
chr5	2435887	2436407	+	DDB_G0289159	DDB_G0289159	NA
chr5	2436601	2437281	-	DDB_G0289161	DDB_G0289161	NA
chr5	2437452	2437748	-	DDB_G0289163	DDB_G0289163	NA
chr5	2438822	2439145	-	DDB_G0289165	matA	NA
chr5	2439587	2440889	-	DDB_G0289171	DDB_G0289171	conserved hypothetical Dictyostelium protein
chr5	2441551	2442522	-	DDB_G0289167	DDB_G0289167	similar to bacterial short-chain dehydrogenase%2Freductase family proteins%2C and human RDH8 (retinol dehydrogenase 8)
chr5	2444140	2445479	+	DDB_G0289181	gnb1l	ortholog of the mammalian GNB1L%3B contains several WD-40 repeats
chr5	2445521	2447857	-	DDB_G0289183	DDB_G0289183	NA
chr5	2448283	2451363	+	DDB_G0289185	DDB_G0289185	NA
chr5	2451919	2452870	+	DDB_G0289187	H2Av1	NA
chr5	2453090	2453879	-	DDB_G0289189	psmD10	NA
chr5	2454071	2455111	+	DDB_G0289191	DDB_G0289191	NA
chr5	2455467	2456419	+	DDB_G0289193	H2Av2	NA
chr5	2456763	2457653	+	DDB_G0289195	DDB_G0289195	highly similar to bacterial proteins electronically annotated as arginine deaminases
chr5	2457890	2458267	+	DDB_G0289197	H2Av3	NA
chr5	2458510	2460913	-	DDB_G0289199	DDB_G0289199	NA
chr5	2461603	2463570	-	DDB_G0289201	mfsd1	ortholog of the human MSFD1%2C also knon as SMAP-4 (Smooth Muscle cell-Associated Protein 4)%3B contains 10 putative transmembrane domains and an additional potential signal peptide
chr5	2464468	2465096	+	DDB_G0289203	DDB_G0289203	NA
chr5	2467250	2472115	+	DDB_G0289205	DDB_G0289205	NA
chr5	2473231	2477932	+	DDB_G0289207	tmcB	contains two HAT (half a TPR) repeats and 13 predicted transmembrane domains%3B involved in macrocyst formation
chr5	2478124	2479050	-	DDB_G0289209	DDB_G0289209	NA
chr5	2479410	2485114	-	DDB_G0289175	DG1091	NA
chr5	2485943	2487524	+	DDB_G0289211	DDB_G0289211	contains a central%2C large T4 RNA ligase%2C RnlA-like domain%2C a property shared by a related gene %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3D%22DDB_G0286041%22%3EDDB_G0286041%3C%2Fa%3E%3B similar to D. purpureum protein
chr5	2487904	2489496	+	DDB_G0289213	DDB_G0289213	NA
chr5	2489574	2491100	-	DDB_G0289215	DDB_G0289215	NA
chr5	2491401	2493112	+	DDB_G0289217	DDB_G0289217	contains one predicted coiled-coil domain
chr5	2493243	2493993	-	DDB_G0289219	DDB_G0289219_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0289227%22%3EDDB_G0289227%3C%2Fa%3E 
chr5	2494619	2497264	+	DDB_G0289221	DDB_G0289221	NA
chr5	2497743	2499857	-	DDB_G0289225	DDB_G0289225_ps	putative pseudogene%3B partial%2C similar to IPT%2FTIG domain-containing proteins%2C e.g %3Ca href%3D%22%2Fgene%2FDDB_G0295757%22%3E DDB_G0295757 %3C%2Fa%3E
chr5	2500724	2503156	-	DDB_G0289227	DDB_G0289227	NA
chr5	2504135	2507598	-	DDB_G0289243	DDB_G0289243	%3Cb%3ECommunity annotation:%3C%2Fb%3E The computer has already noticed that this gene is similar to the widely-conserved folliculin interacting protein FNIP. Dicty in fact has a homolog of folliculin (DDB_G0281111)%2C which the computer has also identified. In mammals%2C folliculin is a tumor suppressor protein%2C mutation of which in the Birt-Hogg-Dube syndrome leads to renal and pulmonary cysts%2C renal cancer%2C and noncancerous tumors of the hair follicles. Folliculin participates in a complex with FNIP1 and FNIP2 which %22binds to AMPK and might therefore interact with energy and nutrient sensing pathways%22 (see Linehan et al (Nature Reviews Urology 7%2C 277-85 (2010)). %3Ci%3EHarry MacWilliams%2C July 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0289243%22%3E There is more information on the wiki page%3C%2Fa%3E 
chr5	2508266	2509160	-	DDB_G0289179	thyB	calmodulin-binding thymidine kinase 1 that is very similar to human TK1%3B catalyzes the reaction ATP %2B thymidine %3D ADP %2B thymidine 5%27-phosphate
chr5	2510064	2513156	-	DDB_G0289229	adcF	NA
chr5	2516577	2517682	+	DDB_G0289173	arfA	NA
chr5	2518176	2518340	-	DDB_G0289245	DDB_G0289245	NA
chr5	2519340	2520881	+	DDB_G0289231	DDB_G0289231	member of the peptidase S28 family of serine proteases%2C a group containing lysosomal Pro-X carboxypeptidase%2C dipeptidyl-peptidase II%2C and thymus-specific serine peptidase
chr5	2521042	2523874	-	DDB_G0289233	DDB_G0289233	similar to human and S. cerevisiae VAC14 (vacuole morphology and inheritance protein 14)%3B contains 3 HEAT repeats
chr5	2524160	2526858	+	DDB_G0289235	DDB_G0289235	NA
chr5	2526970	2531181	-	DDB_G0289237	tirA	enriched expression in sentinel cells and involved in sustained growth on bacteria and in pathogen response to virulent bacteria
chr5	2531958	2535264	-	DDB_G0289177	myoF	NA
chr5	2536641	2538194	+	DDB_G0289247	apm1	shares 69%25 identity with the mouse mu1A
chr5	2538517	2540596	-	DDB_G0289261	DDB_G0289261_ps	putative pseudogene%3B similar to family of Endotoxin_N-terminal domain-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0293578%22%3EDDB_G0293578%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0289249%22%3EDDB_G0289249%3C%2Fa%3E
chr5	2541277	2543356	+	DDB_G0289249	DDB_G0289249	NA
chr5	2543934	2544350	+	DDB_G0289251	DDB_G0289251	belongs to the PLAC8 family (placenta-specific gene 8 protein)%2C a family of cysteine-rich proteins with highly divergent%2C low complexity amino terminal regions%3B similar to D. purpureum protein
chr5	2544506	2549019	-	DDB_G0289253	tmcC	contains two HAT (half a TPR) repeats and 13 predicted transmembrane domains%3B null mutant has an increased number of peripheral cells in macrocyst formation
chr5	2550132	2550213	-	DDB_G0295283	tRNA-Leu-AAG-6	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr5	2550795	2550926	+	DDB_G0289255	DDB_G0289255	NA
chr5	2551579	2556233	+	DDB_G0289257	set1	NA
chr5	2556391	2557506	-	DDB_G0289259	DDB_G0289259	similar to bacterial%2C fungal and plant proteins from the short-chain dehydrogenase%2Freductase family
chr5	2557966	2561225	-	DDB_G0289263	DDB_G0289263	NA
chr5	2561379	2563106	-	DDB_G0289277	nek4	similar to vertebrate Nek kinases%2C serine-threonine kinases that are involved in regulation of mitosis%3B most similar to Nek4
chr5	2564981	2566834	-	DDB_G0289265	DDB_G0289265	has similarity to flavin containing monoamine oxidases%3B contains one amino oxidase domain
chr5	2568808	2569158	+	DDB_G0289267	DDB_G0289267	NA
chr5	2569964	2570826	+	DDB_G0289269	DDB_G0289269	NA
chr5	2571168	2571946	+	DDB_G0289271	gins1	subunit 1 of the conserved replication complex GINS%2C which is essential for initiation of DNA replication in X. laevis
chr5	2572028	2575321	-	DDB_G0289273	DDB_G0289273	NA
chr5	2576362	2577437	-	DDB_G0289275	DDB_G0289275	NA
chr5	2578513	2579446	+	DDB_G0289279	DDB_G0289279_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr5	2579548	2581619	-	DDB_G0295749	DDB_G0295749	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0289407%22%3E%3Ci%3EDDB_G0289407%3C%2Fi%3E%3C%2Fa%3E
chr5	2582433	2584022	-	DDB_G0295747	DDB_G0295747	NA
chr5	2584317	2584595	-	DDB_G0295745	DDB_G0295745	NA
chr5	2585363	2585443	-	DDB_G0295617	sno5	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr5	2586031	2586108	-	DDB_G0295631	sno16	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr5	2586654	2589420	-	DDB_G0295743	DDB_G0295743	NA
chr5	2590095	2590994	+	DDB_G0295753	DDB_G0295753	very similar to %3Ci%3EDictyostelium mcfN%3C%2Fi%3E and to human SLC25A3 and %3Ci%3ES. cerevisiae MIR1%3C%2Fi%3E%2C which transports inorganic phosphate from the cytosol to the mitochondrion matrix
chr5	2591112	2592677	-	DDB_G0295755	glnA2	catalyzes the reaction ATP %2B L-glutamate %2B ammonia %3D ADP %2B phosphate %2B L-glutamine
chr5	2593624	2593696	-	DDB_G0295281	tRNA-Arg-UCU-12	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr5	2598434	2599534	+	DDB_G0289285	DDB_G0289285	putative secreted protein%3B contains a predicted signal sequence%3B similar to D. purpureum protein
chr5	2599917	2599999	-	DDB_G0295619	sno2	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr5	2600252	2600331	-	DDB_G0295621	sno13	expressed non-coding RNA%3B C%2FD box snoRNAs are involved in rRNA processing and methylation
chr5	2600762	2604589	+	DDB_G0289287	DDB_G0289287	NA
chr5	2604715	2606297	-	DDB_G0289303	DDB_G0289303	NA
chr5	2606597	2606863	-	DDB_G0295759	DDB_G0295759	NA
chr5	2607143	2607541	+	DDB_G0289293	DDB_G0289293	NA
chr5	2607639	2607824	+	DDB_G0289295	DDB_G0289295	NA
chr5	2607950	2608345	-	DDB_G0295813	DDB_G0295813	NA
chr5	2608554	2608757	-	DDB_G0295815	DDB_G0295815_ps	putative pseudogene%2C very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268732%22%3EDDB_G0268732%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0275483%22%3EDDB_G0275483%3C%2Fa%3E
chr5	2609390	2610786	-	DDB_G0289307	DDB_G0289307_ps	putative pseudogene%3B highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0288419%22%3E%3Ci%3EDDB_G0288419%3C%2Fi%3E%3C%2Fa%3E
chr5	2612450	2614759	-	DDB_G0289283	cupC	highly conserved protein family up-regulated by Ca2%2B%3B expressed throughout vegetative cells and in the cortex of aggregating cells
chr5	2616286	2619684	-	DDB_G0289309	DDB_G0289309	carboxyl terminus is highly similar to that of cup (calcium up-regulated) genes%2C but the rest of the protein shares little similarity
chr5	2619812	2620714	-	DDB_G0289315	DDB_G0289315	NA
chr5	2622270	2624476	-	DDB_G0289311	DDB_G0289311	contains 7 putative transmembrane domains
chr5	2634493	2636111	-	DDB_G0289317	drg1	ortholog of human DRG1%2C which may be involved in cell proliferation%2C differentiation and death%3B highly conserved in eukaryotes%3B belongs to the GTP1%2FOBG family
chr5	2637678	2640602	+	DDB_G0289321	DDB_G0289321	NA
chr5	2641022	2643751	-	DDB_G0289319	mybQ	contains two Myb DNA-binding domains
chr5	2645520	2645708	-	DDB_G0289377	DDB_G0289377	NA
chr5	2646115	2648078	-	DDB_G0289333	DDB_G0289333	NA
chr5	2648590	2648706	-	DDB_G0348868	DDB_G0348868	NA
chr5	2650999	2652299	-	DDB_G0289325	scsA	catalyzes the reaction GTP %2B succinate %2B CoA %3D GDP %2B phosphate %2B succinyl-CoA
chr5	2652694	2654757	-	DDB_G0289335	DDB_G0289335	NA
chr5	2656525	2661111	+	DDB_G0289337	DDB_G0289337	NA
chr5	2661517	2662195	+	DDB_G0289339	med21	ortholog of the mediator of RNA polymerase II transcription subunit 21%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr5	2662531	2663623	+	DDB_G0289341	DDB_G0289341	C-terminal half has similarity to yeast E3 SUMO-protein ligase MMS21 (NSE2)%2C which acts in a DNA repair pathway for removal of UV-induced DNA damage%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  DDB_G0289341 is similar (best Blast hit%2C both ways) to nse2%2C an E3 sumo protein ligase which acts  in a complex with SMC5 and SMC6 in homologous recombination and telomere maintenance  (see Murray and Carr%2C Nature Reviews Molecular Cell Biology 9%2C 177-182 (2008)).  Both of these processes are associated with chromosomal replication. DDB_G0289341  is overexpressed threefold in a Dicty strain in which the retinoblastoma-like gene rblA  is disrupted (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E) (Doquang et al%2C in preparation). Most genes associated with S-phase or mitosis  are overexpressed in this strain%2C including other genes probably involved in homologous  recombination%2C such as rfaA1%2C recA%2C rad51%2C rad51c%2C rad52 and rad54%2C and telomere maintenance%2C  including %3Ca href%3D%22%2Fgene%2FDDB_G0287899%22%3EDDB_G0287899%3C%2Fa%3E (rif1)%2C %3Ca href%3D%22%2Fgene%2FDDB_G0293070%22%3EDDB_G0293070%3C%2Fa%3E (TEP1)%2C %3Ca href%3D%22%2Fgene%2FDDB_G0268660%22%3EDDB_G0268660%3C%2Fa%3E (NAM7).  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C September 2009 %3C%2Fi%3E
chr5	2664172	2666540	+	DDB_G0289343	sgkD	weakly similar to sphingosine kinase
chr5	2666970	2668322	+	DDB_G0289345	DDB_G0289345	NA
chr5	2668661	2669588	-	DDB_G0289347	DDB_G0289347	NA
chr5	2670443	2671921	+	DDB_G0289349	DDB_G0289349	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity%3B also contains an N-terminal transmembrane domain
chr5	2672362	2676833	+	DDB_G0289351	DDB_G0289351	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and 4 extracellular EGF domains
chr5	2677137	2678075	+	DDB_G0289353	cox11	ortholog of COX11%2C the mitochondrial inner membrane protein required for delivering copper to subunit 1 of cytochrome c oxidase.
chr5	2678322	2679738	-	DDB_G0289379	syn1A	similar to syntaxin 1%2C a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusion
chr5	2681578	2683470	+	DDB_G0289355	DDB_G0289355	NA
chr5	2683596	2684940	-	DDB_G0289327	sevA	Ca2%2B-dependent F-actin fragmenting protein
chr5	2685876	2687546	+	DDB_G0289357	DDB_G0289357	NA
chr5	2687826	2687990	-	DDB_G0289359	DDB_G0289359	NA
chr5	2688872	2693458	+	DDB_G0289331	abcG16	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr5	2694067	2695260	-	DDB_G0289329	dmtA	catalyzes the last step in DIF-1 synthesis
chr5	2697784	2700677	+	DDB_G0289381	DDB_G0289381	NA
chr5	2700736	2704435	+	DDB_G0295675	DDB_G0295675	contains a putative signal peptide and a C-terminal transmembrane domain
chr5	2705143	2706968	+	DDB_G0289361	csn2	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8)
chr5	2707148	2707519	-	DDB_G0289363	DDB_G0289363	NA
chr5	2708637	2709680	-	DDB_G0289365	gghB	catalyses the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates
chr5	2710003	2713807	-	DDB_G0289367	agnE	NA
chr5	2714901	2721923	+	DDB_G0289385	DDB_G0289385	NA
chr5	2722171	2723710	+	DDB_G0289369	DDB_G0289369	contains an AN1-type at the amino terminus and a UBX domain%2C found in ubiquitin-regulatory proteins%2C at the carboxyl terminus
chr5	2724036	2727148	+	DDB_G0289371	copG	gamma subunit of the coatomer complex essential for the secretory pathway
chr5	2727390	2727462	+	DDB_G0295243	tRNA-Lys-UUU-17	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr5	2728188	2728259	-	DDB_G0295279	tRNA-Asp-GUC-20	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr5	2728693	2729786	+	DDB_G0289387	DDB_G0289387_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr5	2730874	2731084	+	DDB_G0289441	DDB_G0289441_RTE	ORF2 protein fragment of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr5	2732174	2736382	-	DDB_G0289389	dtfA	NA
chr5	2737271	2738674	+	DDB_G0289395	crlB	belongs to the serpentine%2FG-protein coupled receptor family
chr5	2739034	2740700	-	DDB_G0289397	DDB_G0289397	NA
chr5	2741182	2743346	+	DDB_G0289433	DDB_G0289433_ps	putative pseudogene%3B almost identical to %3Ca href%3D%22%2Fgene%2FDDB_G0287665%22%3EDDB_G0287665%3C%2Fa%3E%2C although significantly shorter  at 5%27end
chr5	2743899	2746002	+	DDB_G0289399	DDB_G0289399	contains 3 laminin-type EGF-like domains%3B contains one IPT%2FTIG domain that has an immunoglobulin-like fold%3B contains one predicted C-terminal transmembrane domain
chr5	2746763	2747556	+	DDB_G0289435	arrF	NA
chr5	2747783	2748026	-	DDB_G0295623	rnu2d	component of the spliceosome involved in pre-mRNA splicing
chr5	2748299	2749078	-	DDB_G0289401	DDB_G0289401	NA
chr5	2749137	2750290	-	DDB_G0289403	DDB_G0289403	NA
chr5	2750374	2750968	-	DDB_G0289437	DDB_G0289437	NA
chr5	2751258	2752007	+	DDB_G0289405	DDB_G0289405_ps	putative pseudogene%3B very similar to parts of DDB_G0289409
chr5	2752168	2755046	-	DDB_G0289407	DDB_G0289407	almost identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0295749%22%3E%3Ci%3EDDB_G0295749%3C%2Fi%3E%3C%2Fa%3E
chr5	2755696	2767924	+	DDB_G0289409	DDB_G0289409	NA
chr5	2768640	2768712	+	DDB_G0295245	tRNA-Lys-UUU-18	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr5	2771756	2772199	-	DDB_G0289411	DDB_G0289411	NA
chr5	2773421	2774944	+	DDB_G0289413	DDB_G0289413	NA
chr5	2775105	2777239	-	DDB_G0289415	DDB_G0289415	NA
chr5	2778983	2779470	+	DDB_G0289439	DDB_G0289439	member of the HIT superfamily involved in nucleotide binding
chr5	2779634	2779903	-	DDB_G0289427	DDB_G0289427	NA
chr5	2780778	2781871	-	DDB_G0289419	DDB_G0289419_ps	putative pseudogene%3B fragment%2C very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0289421%22%3E DDB_G0289421 %3C%2Fa%3E that has Mis18-alpha and beta similarity
chr5	2783089	2783551	+	DDB_G0289391	pkiA	similar to protein kinase C inhibitor
chr5	2784742	2786502	-	DDB_G0289421	DDB_G0289421	has limited similarity to mammalian Mis18-alpha and beta (MIS18A%2C MIS18B) that are required for normal chromosome segregation during mitosis%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0289421 is weakly similar (first Blast hit%2C both ways) to Mis18-alpha and Mis18-beta. In mammals these two closely related proteins are necessary for loading histone H3 variant CENP-A onto centromeric chromatin at the telophase%2FG1 boundary%2C (see Fujita et al%2C Developmental Cell 12%2C 17-30 (2007). Knockdown of Mis18-alpha%2C Mis18-beta%2C or the third component of this complex (M18BP1) leads to misalignment of mitotic chromosomes%2C presumably at the following mitosis%2C and apparently without activation of the spindle checkpoint.%3Cbr%3E In Dicty there appears to be only one Mis18%2C and neither M18BP1 nor CENP-A itself is identifiable. DDB_G0289421 nonetheless appears to be a cell cycle gene: it is overexpressed threefold (p%3C5e-11) in a strain in which the retinoblastoma-like gene rblA has been disrupted. Most genes with known functions in S-phase or mitosis are overexpressed in this strain%2C and most overexpressed genes have cell cycle functions. DDB_G0289421 also shows the developmental time course (low at T0 and T4%2C high at T8%2C T12%2C and T16%2C then low again at T20 and T24) shown by most cell cycle genes in Dictyostelium. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E
chr5	2787284	2789636	+	DDB_G0289429	lmnB	similar to mammalian lamin B1%3B localizes to the inner membrane of the nuclear envelope%2C involved in chromatin and centrosome organization and stabilization
chr5	2790892	2793454	+	DDB_G0289393	psiH	contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 4 Dictyostelium (CTDC) repeats and a C-terminal transmembrane domain
chr5	2794822	2798067	+	DDB_G0289423	DDB_G0289423	similar to mammalian XPR1%2C which may confer susceptibility to infection with murine leukaemia viruses%3B also similar to yeast SYG1%2C a G-protein associated signal transduction protein%2C and plant PHO1%2C that may be involved in phosphate transport 
chr5	2802474	2802784	-	DDB_G0289443	DDB_G0289443	small Dictyostelium protein family%3B expressed in pstO cells and in upper cup during culmination
chr5	2803733	2805584	-	DDB_G0289445	prmt2	ortholog of H. sapiens PRMT2
chr5	2806080	2806391	+	DDB_G0289451	tmem167	conserved protein containing a signal peptide and a transmembrane domain
chr5	2807299	2808072	-	DDB_G0289453	DDB_G0289453	possible homolog of human LSM11%2C a U7 snRNA-associated Sm-like protein
chr5	2808377	2809546	+	DDB_G0289455	DDB_G0289455	NA
chr5	2809612	2810612	-	DDB_G0289457	DDB_G0289457	NA
chr5	2811202	2812803	+	DDB_G0289449	ubqF	NA
chr5	2812938	2813519	-	DDB_G0289459	DDB_G0289459	NA
chr5	2814027	2816075	-	DDB_G0289461	DDB_G0289461	putative ortholog of H. sapiens CNOT6 and S. cerevisiae CCR4%3B component of the CCR4-NOT transcription complex
chr5	2816488	2817662	+	DDB_G0289463	srr	converts L-serine into D-serine%2C activated in vitro by Mg as well as Na%3B pyridoxal 5%27-phosphate (PLP)-dependent enzyme that catalyzes racemization and dehydration of both isomers of serine
chr5	2818342	2820952	+	DDB_G0289465	DDB_G0289465	NA
chr5	2821081	2823256	-	DDB_G0289467	DD8-14	involved in O-glycosylation as identified by mRNA differential display
chr5	2823825	2826023	-	DDB_G0289479	swp1	subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of S. cerevisiae SWP1 and human ribophorin II%3B contains three putative C-terminal transmembrane domains and an N-terminal signal peptide
chr5	2826905	2829058	+	DDB_G0289469	DDB_G0289469	similar to D. purpureum and P. pallidum protein%3B C-terminal region similar to ribosomal protein S15P family
chr5	2829282	2830299	-	DDB_G0289471	auh	catalyzes the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA %3D trans-3-methylglutaconyl-CoA %2BH2O%3B ortholog of the human AUH protein that was identified as an RNA-binding protein that binds to clustered 5%27-AUUUA-3%27 motifs (EC 4.2.1.18)
chr5	2830601	2833935	-	DDB_G0289473	DDB_G0289473	ortholog of the conserved plasma membrane calcium ATPases (PMCA) such as %3Ci%3EDictyostelium%3C%2Fi%3E PAT1%3B contains at least 8 predicted transmembrane domains
chr5	2834711	2834986	-	DDB_G0289475	sdhaf1A	NA
chr5	2835235	2836934	+	DDB_G0289477	rmp	similar to the human unconventional prefoldin RPB5 interactor a putative scaffolding protein with roles in transcription and ubiquitination
chr5	2837078	2839594	-	DDB_G0294611	DDB_G0294611	NA
chr5	2840200	2846157	-	DDB_G0289447	myoH	NA
chr5	2847194	2848641	-	DDB_G0289483	ctxA	member of the alpha-actinin%2Fspectrin superfamily%2C dimerizes with cortexillin II%3B involved in cytokinesis and development and associates with the actin cytoskeleton
chr5	2849682	2849855	-	DDB_G0289491	DDB_G0289491	NA
chr5	2850667	2851044	-	DDB_G0289493	DDB_G0289493	NA
chr5	2851858	2855530	+	DDB_G0289495	DDB_G0289495	NA
chr5	2856146	2856481	+	DDB_G0289497	DDB_G0289497	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0289497 has been alleged to be a member of the dickkopf family (Guder et al%2C 2006%2C Development 133%2C 901-911 ). Mammals have four dickkopf genes (Dkk1%2C Dkk2%2C Dkk3 and Dkk4)%2C of which Dkk1%2C 2 and 4 have been shown to be secreted antagonists of wingless signalling. Heterologous expression of any of these in vertebrate embryos leads to a reduction of posterior structures with accompanying enhancement of the head%3B hence the name dickkopf%2C which literally means fathead in German (Glinka et al%2C 1998%2C Nature 391%2C 357-362). The Dictyostelium gene is most similar to Dkk3%2C which is somewhat divergent from the others (see Niehrs%2C 2006%2C Oncogene 25%2C 7469-7481). Members of the Dkk3 subfamily have signal peptides (as does DDB_G0289497) and are probably secreted proteins.  %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0289497%22%3E There is more information on the wiki page%3C%2Fa%3E %3Cbr%2F%3E%3Ci%3EJune 9%2C 2008 Harry K. MacWilliams  %3C%2Fi%3E
chr5	2857147	2859666	+	DDB_G0289481	glnS	induced by cycloheximide%3B catalyzes the reaction ATP %2B L-glutamine %2B tRNAGln %3D AMP %2B diphosphate %2B L-glutaminyl-tRNAGln
chr5	2859869	2860286	-	DDB_G0289499	lsm7	member of heteromeric complexes involved in mRNA splicing (lsm2-8) and mRNA degradation (lsm1-7)
chr5	2860682	2862469	+	DDB_G0289501	cdc40	conserved splicing factor%3B S. cerevisiae cdc40 is important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression
chr5	2862639	2867839	-	DDB_G0289529	DDB_G0289529	NA
chr5	2868325	2873664	-	DDB_G0289503	DDB_G0289503_ps	putative pseudogene%3B almost identical to neighboring gene %3Ca href%3D%22%2Fgene%2FDDB_G0289529%22%3EDDB_G0289529%3C%2Fa%3E
chr5	2874594	2875725	+	DDB_G0289525	act30_ps	putative pseudogene%2C contains an actin domain
chr5	2876728	2877861	+	DDB_G0289505	act24	has 80%25 identity with human beta-actin (SwissProt P60709)
chr5	2878511	2879668	+	DDB_G0289507	act25	has 74%25 identity with human beta-actin (SwissProt P60709)
chr5	2880348	2881466	+	DDB_G0289533	act27	has 61%25 identity with human beta-actin (SwissProt P60709)
chr5	2881811	2882459	+	DDB_G0289509	act36_ps	putative pseudogene%3B contains a partial actin domain
chr5	2883081	2884142	+	DDB_G0289511	act28	contributes to DdPPK2 activity%2C also described as member of the polyphosphate kinase PPK3 family
chr5	2884652	2885782	+	DDB_G0289487	act3	has 92%25 identity with human beta-actin (SwissProt P60709) and 11 amino acid differences compared to the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)
chr5	2886806	2887948	+	DDB_G0289489	act18	has 83%25 identity with human beta-actin (SwissProt P60709)
chr5	2888908	2890870	+	DDB_G0289485	vacA	expressed in post-lysosomal vacuole
chr5	2891660	2893699	+	DDB_G0289513	rfa1	putative ortholog of heterotrimeric RPA (RF-A) single-stranded DNA binding protein 69 kDa subunit
chr5	2893954	2895241	-	DDB_G0289541	vasP	VASP family member involved in filopodium formation and in controlling the actin cytoskeleton during chemotaxis
chr5	2896095	2897664	-	DDB_G0289515	pigS	NA
chr5	2897974	2900900	+	DDB_G0289535	cog5	highly similar to COG5%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits
chr5	2901066	2903382	-	DDB_G0289517	DDB_G0289517	expressed in pstAO cells and in upper cup during culmination
chr5	2904697	2906667	-	DDB_G0289519	DDB_G0289519	NA
chr5	2908181	2910485	+	DDB_G0289537	DDB_G0289537	NA
chr5	2911167	2911622	+	DDB_G0289521	srsA	immidiate-early gene%2C expressed immidiately after nutrition removal%2C involved in starvation response%2C development and spore differentiation%3B there are two transcripts of this gene%3B both contain a putative transmembrane domain
chr5	2912060	2912532	+	DDB_G0289527	DDB_G0289527	NA
chr5	2913451	2914259	-	DDB_G0289523	copZa	zeta subunit of the coatomer complex essential for the secretory pathway%3B there is another gene encoding a zeta subunit%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0293086%22%3E %3Ci%3EcopZb%3C%2Fi%3E%3C%2Fa%3E
chr5	2914742	2916626	+	DDB_G0289539	DDB_G0289539	NA
chr5	2920470	2926808	+	DDB_G0289543	ndrD	member of the AGC kinase group%2C NDR family%3B related to mammalian LATS1 and LATS2 (LArge Tumor Suppressor homolog) kinases
chr5	2926893	2930675	-	DDB_G0289545	DDB_G0289545	NA
chr5	2930859	2932103	+	DDB_G0289547	DDB_G0289547	ortholog of yeast CUS2 (Cold sensitive U2 snRNA Suppressor) and human HTATSF1 (HIV TAT specific factor 1)
chr5	2932427	2932696	+	DDB_G0289549	DDB_G0289549	NA
chr5	2933097	2935349	-	DDB_G0289551	DDB_G0289551	NA
chr5	2938326	2939456	-	DDB_G0289553	act1	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E) 
chr5	2941850	2946232	+	DDB_G0289555	arkA	suppressor of spalten (spnA) mutant%3B member of the TKL (tyrosine kinase-like) group and ARK (ankyrin repeat-containing kinase) family
chr5	2946489	2949226	-	DDB_G0289557	DDB_G0289557	NA
chr5	2951390	2954166	+	DDB_G0289561	DDB_G0289561	NA
chr5	2954406	2954943	-	DDB_G0289563	mlcC	light chain that binds to the neck region of myoC%3B contains two calcium-binding EF-hand motifs%2C but does not bind calcium
chr5	2956680	2956750	+	DDB_G0295247	tRNA-Pro-UGG-13	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr5	2957193	2957796	+	DDB_G0289567	DDB_G0289567_ps	putative pseudogene%3B fragment%2C similar to FNIP repeat containing proteins
chr5	2958707	2962052	+	DDB_G0289571	DDB_G0289571	NA
chr5	2964470	2966659	+	DDB_G0289577	DDB_G0289577	contains an N-terminal F-box domain and C-terminal leucine-rich repeats
chr5	2967354	2967919	+	DDB_G0289579	DDB_G0289579	NA
chr5	2970447	2970517	-	DDB_G0295277	tRNA-Pro-UGG-14	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr5	2971496	2972644	+	DDB_G0289575	DDB_G0289575	NA
chr5	2973076	2973749	-	DDB_G0289573	DDB_G0289573	ortholog of the conserved protein ENY2 that in D. melanogaster is involved in the regulation of transcription
chr5	2974797	2977217	+	DDB_G0289591	DDB_G0289591	NA
chr5	2977521	2978795	-	DDB_G0289593	tufM	mitochondrial translation elongation factor Tu%3B highly similar to bacterial elongation factor Tu
chr5	2981034	2983254	+	DDB_G0289587	DDB_G0289587	belongs to the RRN3 family%3B similar to human and S. cerevisiae RRN3 (RNA polymerase I-specific transcription initiation factor RRN3)
chr5	2984110	2985612	-	DDB_G0289595	prpf31	component of the U4%2FU6-U5 snRNP complex%3B defects in human PRPF31 are the cause of retinitis pigmentosa 11 (RP11)
chr5	2986116	2988091	-	DDB_G0304961	tmem184E	TMEM184 family protein%3B contains 7 predicted transmembrane domains
chr5	2989530	2991117	-	DDB_G0289585	DDB_G0289585	leucine-rich repeat protein with filamin%2FABP280 at the carboxyl terminus
chr5	2992157	2996185	-	DDB_G0289583	DDB_G0289583	ortholog of human SDCCAG1 (serologically defined colon cancer antigen 1)%2C a conserved eukaryotic protein of unknown function
chr5	2997750	2998627	-	DDB_G0289581	DDB_G0289581	NA
chr5	3001531	3003208	+	DDB_G0289651	gtaO	has 18 amino acids between the two CX2C motifs
chr5	3003747	3004503	-	DDB_G0289599	comA	connects the actin cytoskeleton to the Golgi apparatus%3B actin binding protein%2C bundles actin filaments%3B plays a role in phagocytosis
chr5	3005109	3008075	-	DDB_G0289601	pikE	ortholog of yeast VPS34%2C a phosphatidylinositol 3-kinase
chr5	3008595	3011873	-	DDB_G0289635	DDB_G0289635	NA
chr5	3013032	3016634	-	DDB_G0289603	DDB_G0289603	NA
chr5	3016817	3018382	-	DDB_G0289605	fmoC	belongs to the fmo family%3B similar to flavin-containing monooxygenases from a variety of eukaryotes%3B involved in the metabolism of xenobiotic compounds
chr5	3018845	3019348	-	DDB_G0289607	DDB_G0289607	NA
chr5	3019826	3020505	-	DDB_G0289609	DDB_G0289609	contains two CBS domains%3B expressed in pstAO cells and in upper cup during culmination
chr5	3021100	3026224	-	DDB_G0289611	usp40	putative ortholog of H. sapiens USP40
chr5	3026939	3031174	-	DDB_G0289613	gefAA	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr5	3032158	3034230	+	DDB_G0289615	DDB_G0289615	NA
chr5	3034658	3035431	+	DDB_G0289617	DDB_G0289617	NA
chr5	3035690	3038887	+	DDB_G0289637	DDB_G0289637	NA
chr5	3039503	3041122	+	DDB_G0289641	DDB_G0289641	NA
chr5	3042065	3042780	+	DDB_G0289619	DDB_G0289619_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289849%22%3EDDB_G0289849%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0289641%22%3EDDB_G0289641%3C%2Fa%3E 
chr5	3043521	3044234	+	DDB_G0289621	DDB_G0289621	NA
chr5	3044413	3045177	-	DDB_G0289623	pex11	ortholog of peroxisomal protein peroxin 11%3B contains three putative transmembrane domains
chr5	3045458	3046178	+	DDB_G0289625	DDB_G0289625	NA
chr5	3046500	3048830	-	DDB_G0289627	DDB_G0289627	NA
chr5	3049902	3052227	-	DDB_G0289629	DDB_G0289629	NA
chr5	3052862	3053826	-	DDB_G0289643	DDB_G0289643	NA
chr5	3054610	3055402	+	DDB_G0289631	DDB_G0289631_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0289643%22%3EDDB_G0289643%3C%2Fa%3E 
chr5	3055772	3056586	+	DDB_G0289645	pemtB	homolog of mammalian PEMT and S. cerevisiae OPI3%2C which catalyzes the steps in phosphatidylcholine biosynthesis
chr5	3056743	3057810	-	DDB_G0289647	DDB_G0289647_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290571%22%3EDDB_G0290571%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290507%22%3EDDB_G0290507%3C%2Fa%3E
chr5	3058125	3058292	-	DDB_G0289649	DDB_G0289649	NA
chr5	3060165	3061184	-	DDB_G0289793	DDB_G0289793_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr5	3061365	3061438	+	DDB_G0295249	tRNA-Val-UAC-3	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3062303	3064858	-	DDB_G0289655	abcG7	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr5	3066245	3068641	-	DDB_G0289657	abcG4	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr5	3069414	3071188	-	DDB_G0289669	DDB_G0289669	NA
chr5	3072697	3073753	+	DDB_G0289671	DDB_G0289671	similar to human ABHD13 (Abhydrolase domain-containing protein 13) and S. pombe bem46%3B contains one putative transmembrane domain
chr5	3074556	3077608	+	DDB_G0289673	DDB_G0289673	NA
chr5	3077727	3079189	-	DDB_G0289675	adprh	conserved enzyme%3B catalyzes the reaction: N(omega)-(ADP-D-ribosyl)-L-arginine %2B H(2)O %3D ADP-ribose %2B L-arginine%3B reverses the reaction of mono-ADP-ribosylation
chr5	3079913	3080156	-	DDB_G0289783	DDB_G0289783_ps	putative pseudogene%3B similar to a family of small D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0271110 %22%3EDDB_G0271110 %3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0293698%22%3EDDB_G0293698%3C%2Fa%3E
chr5	3081562	3082929	+	DDB_G0289677	hbx14	NA
chr5	3085619	3089627	+	DDB_G0289665	gefQ	 RasB guanine nucleotide exchange factor that promotes the exchange of GDP for GTP converting RasB into the active form 
chr5	3090972	3091571	-	DDB_G0289679	DDB_G0289679	NA
chr5	3092553	3093416	-	DDB_G0289681	DDB_G0289681	NA
chr5	3093903	3096689	+	DDB_G0289683	DDB_G0289683	NA
chr5	3096922	3099528	+	DDB_G0289685	DDB_G0289685	NA
chr5	3100083	3102016	+	DDB_G0289795	DDB_G0289795	NA
chr5	3103046	3105739	+	DDB_G0289687	DDB_G0289687	NA
chr5	3105859	3107448	-	DDB_G0289787	DDB_G0289787	NA
chr5	3108150	3111510	-	DDB_G0289689	DDB_G0289689	NA
chr5	3111862	3113484	-	DDB_G0289691	DDB_G0289691	NA
chr5	3113136	3113208	-	DDB_G0295275	tRNA-Lys-UUU-19	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3113883	3114242	-	DDB_G0289693	DDB_G0289693	expressed in prespore cells
chr5	3114892	3115392	-	DDB_G0289695	DDB_G0289695	contains one putative transmembrane domain
chr5	3115871	3117229	+	DDB_G0289697	DDB_G0289697	NA
chr5	3117432	3119277	-	DDB_G0289653	noxA	homolog of the mammalian flavocytochrome b large subunit gp91phox%2C essential for spore formation
chr5	3120417	3120851	+	DDB_G0289699	nola2	component of the H%2FACA small nucleolar ribonucleoprotein (H%2FACA snoRNP) complex required for pre-mRNA processing and pseudouridylation
chr5	3121180	3126609	-	DDB_G0289701	DDB_G0289701	has similarity to nuclear pore protein 214%3B contains a Wd40-like region and a moesin%2C C-terminal domain
chr5	3127157	3130194	+	DDB_G0289703	DDB_G0289703	contains 9 putative transmembrane domains
chr5	3131180	3134890	+	DDB_G0289789	DDB_G0289789	NA
chr5	3136742	3140119	+	DDB_G0289705	DDB_G0289705	NA
chr5	3140427	3142433	+	DDB_G0289667	gefD	NA
chr5	3143077	3144263	+	DDB_G0289707	DDB_G0289707	contains 5 predicted transmembrane domains
chr5	3144874	3146982	+	DDB_G0289791	drkA	member of the TKL (tyrosine kinase-like) group and the DRK (Dictyostelium receptor-like kinase) subfamily
chr5	3147575	3149927	+	DDB_G0289709	drkB	member of the TKL (tyrosine kinase-like) group and the DRK (Dictyostelium receptor-like kinase) subfamily
chr5	3150155	3151253	-	DDB_G0289711	morg1	ortholog of MORG1%2C a molecular scaffold protein that acts as a module in the assembly of a multicomponent scaffold for the ERK (extracellular signal-regulated kinase) pathway%3B contains 7 WD40 repeats
chr5	3151658	3153325	+	DDB_G0289713	DDB_G0289713	NA
chr5	3153407	3154347	-	DDB_G0289715	DDB_G0289715	NA
chr5	3156042	3158082	-	DDB_G0289717	DDB_G0289717	contains one B-box zinc-finger domain and 7 FNIP repeats%3B contains one coiled-coil domain
chr5	3159163	3163422	+	DDB_G0289719	DDB_G0289719	NA
chr5	3163717	3164408	-	DDB_G0289721	ap2s1	NA
chr5	3164865	3164982	-	DDB_G0295625	rnu5a	component of the spliceosome involved in pre-mRNA splicing
chr5	3165224	3165341	+	DDB_G0295627	rnu5b	component of the spliceosome involved in pre-mRNA splicing
chr5	3165541	3166827	-	DDB_G0289723	abhd	NA
chr5	3167501	3169440	-	DDB_G0289725	fscA	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains
chr5	3170582	3172862	+	DDB_G0289727	pyroxd1	conserved eukaryotic protein that is however absent in yeasts
chr5	3173059	3173795	-	DDB_G0289729	DDB_G0289729	NA
chr5	3175755	3177323	-	DDB_G0289731	DDB_G0289731	NA
chr5	3177932	3178682	-	DDB_G0289733	DDB_G0289733	similar to fungal and plant proteins%3B contains 4 putative transmembrane domains
chr5	3179530	3181344	+	DDB_G0289735	DDB_G0289735	NA
chr5	3181881	3186572	+	DDB_G0289737	DDB_G0289737	NA
chr5	3186992	3188122	-	DDB_G0289663	act5	has 94%25 identity with human beta-actin (SwissProt P60709)%3B encodes one of the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)   
chr5	3188713	3189126	-	DDB_G0289739	DDB_G0289739	NA
chr5	3189387	3192901	-	DDB_G0289741	DDB_G0289741	NA
chr5	3193439	3194440	+	DDB_G0289743	DDB_G0289743	NA
chr5	3194481	3195329	-	DDB_G0289745	DDB_G0289745_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0346538%22%3EDDB_G0346538%3C%2Fa%3E
chr5	3196021	3203356	+	DDB_G0289659	rrpA	involved in posttranscriptional gene silencing
chr5	3203632	3204242	-	DDB_G0289747	tgrA_ps6	putative pseudogene%3B fragment of immunoglobulin E-set family gene
chr5	3204528	3206126	-	DDB_G0346538	DDB_G0346538	NA
chr5	3206289	3207884	-	DDB_G0346536	DDB_G0346536	NA
chr5	3208187	3208260	-	DDB_G0295273	tRNA-Val-AAC-19	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3208495	3210036	-	DDB_G0289749	DDB_G0289749	member of the peptidase S28 family of serine proteases%2C a group containing lysosomal Pro-X carboxypeptidase%2C dipeptidyl-peptidase II%2C and thymus-specific serine peptidase
chr5	3211024	3212298	+	DDB_G0289751	DDB_G0289751	NA
chr5	3213101	3215446	+	DDB_G0289753	DDB_G0289753	NA
chr5	3215546	3216258	+	DDB_G0289797	DDB_G0289797_ps	putative pseudogene%3B small fragment of D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0278909%22%3EDDB_G0278909%3C%2Fa%3E
chr5	3216855	3218319	+	DDB_G0289799	DDB_G0289799_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289849%22%3EDDB_G0289849%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0289717%22%3EDDB_G0289717%3C%2Fa%3E
chr5	3219108	3222875	+	DDB_G0289755	DDB_G0289755	NA
chr5	3223411	3224681	+	DDB_G0289757	DDB_G0289757	NA
chr5	3225323	3227134	+	DDB_G0289759	DDB_G0289759	NA
chr5	3227434	3233509	-	DDB_G0289761	DDB_G0289761	NA
chr5	3234217	3236515	+	DDB_G0289801	DDB_G0289801_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289819%22%3EDDB_G0289819%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0283195%22%3EDDB_G0283195%3C%2Fa%3E
chr5	3237701	3241478	-	DDB_G0289763	forF	diaphanous related formin that binds profilin and is a weak actin nucleator%3B involved in development and phototaxis.%3Cbr%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with dia1 named for the differentiation associated protein
chr5	3243093	3243389	-	DDB_G0289765	DDB_G0289765	NA
chr5	3244131	3244427	-	DDB_G0289767	DDB_G0289767	NA
chr5	3245733	3245804	-	DDB_G0295271	tRNA-Glu-UUC-14	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr5	3246114	3247559	+	DDB_G0289769	DDB_G0289769	NA
chr5	3247669	3249534	-	DDB_G0289771	DDB_G0289771	belongs to the major facilitator superfamily%3B similar to human SLC43A3 (solute carrier family 43 member 3)%3B contains 12 putative transmembrane domains
chr5	3250091	3251443	-	DDB_G0289773	DDB_G0289773	NA
chr5	3251908	3253164	+	DDB_G0347657	DDB_G0347657	NA
chr5	3253562	3254956	+	DDB_G0347658	DDB_G0347658	NA
chr5	3255902	3257939	+	DDB_G0289661	kinY	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family%3B similar to LIM kinases which regulate actin dynamics
chr5	3258199	3259297	-	DDB_G0289777	DDB_G0289777_ps	putative pseudogene%3B fragment%2C similar to FNIP repeat containing proteins
chr5	3259385	3265001	+	DDB_G0289805	DDB_G0289805_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr5	3259687	3259759	+	DDB_G0295251	tRNA-Met-CAU-13	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3265452	3267137	-	DDB_G0289779	fmoA	belongs to the fmo family%3B similar to flavin-containing monooxygenases from a variety of eukaryotes%3B involved in the metabolism of xenobiotic compounds
chr5	3268015	3269924	-	DDB_G0289781	DDB_G0289781	NA
chr5	3270257	3272844	-	DDB_G0289807	DDB_G0289807	NA
chr5	3273269	3273762	-	DDB_G0289809	DDB_G0289809_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0289853%22%3EDDB_G0289853%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0289857%22%3EDDB_G0289857%3C%2Fa%3E
chr5	3274098	3274958	-	DDB_G0289853	DDB_G0289853	NA
chr5	3275554	3277147	-	DDB_G0289849	DDB_G0289849	NA
chr5	3277922	3278651	-	DDB_G0289855	DDB_G0289855_ps	putative pseudogene%3B fragment%2C similar to FNIP repeat containing proteins
chr5	3279027	3279887	-	DDB_G0289857	DDB_G0289857	NA
chr5	3280631	3282707	-	DDB_G0289817	DDB_G0289817_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289819%22%3EDDB_G0289819%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0289849%22%3EDDB_G0289849%3C%2Fa%3E
chr5	3283950	3287220	-	DDB_G0289819	DDB_G0289819	NA
chr5	3287942	3289841	-	DDB_G0289851	DDB_G0289851_ps	putative pseudogene%3B similar to a larger gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289819%22%3EDDB_G0289819%3C%2Fa%3E
chr5	3290073	3291248	-	DDB_G0289823	omt9	NA
chr5	3292116	3292651	+	DDB_G0289825	DDB_G0289825	NA
chr5	3292859	3293559	-	DDB_G0289827	rab18	similar to R. norvegicus rab18
chr5	3294597	3308444	+	DDB_G0289829	DDB_G0289829	NA
chr5	3309104	3313120	+	DDB_G0289859	kxcA	member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family%3B contains calmodulin-binding%2C RhoGEF%2C and pleckstrin homology (PH) domains
chr5	3313764	3316073	+	DDB_G0289815	cupB	highly conserved protein family up-regulated by Ca2%2B%3B expressed throughout vegetative cells and in the cortex of aggregating cells%3B cells overexpressing antisense mRNA fail to aggregate
chr5	3317807	3320116	+	DDB_G0289813	cupF	highly conserved protein family up-regulated by Ca2%2B%3B expressed throughout vegetative cells and in the cortex of aggregating cells
chr5	3320745	3321401	+	DDB_G0289831	DDB_G0289831	contains a HDc domain (metal-dependent phosphohydrolases with conserved %22HD%22 motif)%2C indicating possible phosphohydrolase activity
chr5	3321520	3324032	-	DDB_G0289861	DDB_G0289861	predicted secreted protein
chr5	3325551	3326188	+	DDB_G0289833	DDB_G0289833	NA
chr5	3326670	3327377	+	DDB_G0289835	DDB_G0289835	NA
chr5	3327630	3332493	-	DDB_G0289863	DDB_G0289863	NA
chr5	3333090	3335669	-	DDB_G0289865	DDB_G0289865	NA
chr5	3336512	3336601	-	DDB_G0295269	tRNA-Thr-UGU-5	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3337403	3338533	+	DDB_G0289811	act10	has 94%25 identity with human beta-actin (SwissProt P60709) and 1 amino acid difference compared to the 17 identical actin proteins in the %3Ci%3EDictyostelium%3C%2Fi%3E genome (%3Ci%3Eact1%2C act2%2C act4%2C  act5%2C act6%2C act7%2C act8%2C act9%2C act11%2C act12%2C act13%2C act14%2C act15%2C act16%2C act19%2C act20%2C and act21%3C%2Fi%3E)
chr5	3338795	3340114	+	DDB_G0289837	DDB_G0289837	NA
chr5	3340420	3344303	+	DDB_G0289867	pex1	ortholog of peroxin 1%2C AAA-family ATPase peroxin required for peroxisome biogenesis%3B mutations in human homolog cause a variety of peroxisomal disorders
chr5	3345167	3349018	+	DDB_G0289869	DDB_G0289869	NA
chr5	3349145	3351713	-	DDB_G0289839	DDB_G0289839	NA
chr5	3351960	3352351	-	DDB_G0289841	DDB_G0289841_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289837%22%3EDDB_G0289837%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290805%22%3EDDB_G0290805%3C%2Fa%3E
chr5	3352483	3352827	+	DDB_G0289843	DDB_G0289843_ps	putative pseudogene%3B very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268772%22%3EDDB_G0268772%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0275721%22%3EDDB_G0275721%3C%2Fa%3E
chr5	3353422	3354601	-	DDB_G0289871	DDB_G0289871	NA
chr5	3355012	3358747	-	DDB_G0289845	DDB_G0289845_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0277653%22%3EDDB_G0277653%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0277659%22%3EDDB_G0277659%3C%2Fa%3E
chr5	3359151	3362061	-	DDB_G0295737	DDB_G0295737	has similarity to the mammalian PAP associated domain containing 5 (PAPD5) and S. pombe poly(A) polymerase Cid14
chr5	3364902	3365970	-	DDB_G0289887	DDB_G0289887	NA
chr5	3366559	3367291	-	DDB_G0289889	DDB_G0289889	NA
chr5	3367899	3368837	-	DDB_G0289891	DDB_G0289891	contains a putative signal sequence and one additional transmembrane domain
chr5	3369167	3369910	+	DDB_G0289893	ccdc124	NA
chr5	3370229	3373408	-	DDB_G0289895	DDB_G0289895	NA
chr5	3373542	3376475	-	DDB_G0289897	DDB_G0289897	NA
chr5	3376818	3377249	-	DDB_G0289899	DDB_G0289899	NA
chr5	3377583	3378551	-	DDB_G0289965	DDB_G0289965	NA
chr5	3379595	3383123	+	DDB_G0289901	DDB_G0289901	highly repetitive protein%2C serine and glycine rich%3B contains a predicted signal peptide
chr5	3383269	3385061	-	DDB_G0289967	sir2D	NAD-dependent deacetylase Sirutin 2 family protein%2C that regulates various biological processes by deacetylating histones and other target proteins%3B expressed more highly during vegetative growth 
chr5	3385552	3388611	-	DDB_G0289903	DDB_G0289903	NA
chr5	3389153	3390022	+	DDB_G0289905	DDB_G0289905	NA
chr5	3390166	3394872	-	DDB_G0289907	DDB_G0289907	NA
chr5	3396462	3396677	+	DDB_G0289969	DDB_G0289969	NA
chr5	3396878	3400525	-	DDB_G0289909	DDB_G0289909	NA
chr5	3401311	3408014	+	DDB_G0289971	med24	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription 24 (metazoa) or subunit 5 (fungi)%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr5	3408321	3408727	-	DDB_G0289911	DDB_G0289911_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22DDB_G0286157%22%3EDDB_G0286157%3C%2Fa%3E%2C %3Ca href%3D%22DDB_G0272288%22%3EDDB_G0272288%3C%2Fa%3E
chr5	3409130	3410881	-	DDB_G0289973	DDB_G0289973	NA
chr5	3412058	3412951	+	DDB_G0289913	DDB_G0289913	NA
chr5	3412976	3414159	-	DDB_G0289915	DDB_G0289915	NA
chr5	3415174	3418369	+	DDB_G0289917	DDB_G0289917	similar to neighboring gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0289975%22%3E%3Ci%3EDDB_G0289975%3C%2Fi%3E%3C%2Fa%3E
chr5	3419568	3423368	+	DDB_G0289975	DDB_G0289975	similar to neighboring gene%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0289917%22%3E%3Ci%3EDDB_G0289917%3C%2Fi%3E%3C%2Fa%3E
chr5	3425059	3425763	+	DDB_G0289919	ponJ	structurally similar to ponticulins
chr5	3426110	3429896	+	DDB_G0289921	DDB_G0289921	NA
chr5	3430004	3431500	-	DDB_G0289977	DDB_G0289977_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291968%22%3EDDB_G0291968%3C%2Fa%3E 
chr5	3431951	3433642	+	DDB_G0289879	arsB	has two putative transmembrane domains%3B bacterial homolog associates with ArsA to transport arsenate%2C selenate%2C and other anionic compounds outside the cell
chr5	3433996	3435424	+	DDB_G0289881	atg5	Dictyostelium homolog of yeast atg5%3B conjugated to atg12
chr5	3435700	3438515	-	DDB_G0289979	DDB_G0289979	has similarity to mammalian tensin%2C a cytoplasmic phosphoprotein 
chr5	3439159	3441095	-	DDB_G0289875	uppA	catalyzes the reaction UTP %2B alpha-D-glucose 1-phosphate %3C%3D%3E diphosphate %2B UDP-glucose
chr5	3442183	3443496	+	DDB_G0289923	agxt	ortholog of the conserved AGXT%3B defects in the human AGXT cause primary hyperoxaluria type I
chr5	3444195	3446235	+	DDB_G0289961	DDB_G0289961	ortholog of mammalian lunapark (LNP)%2C that may be involved in limb and central nervous system development%3B contains two transmembrane domains
chr5	3446671	3448375	+	DDB_G0289925	fmoG	NA
chr5	3449477	3451192	+	DDB_G0289927	fmoF	belongs to the fmo family%3B similar to flavin-containing monooxygenases from a variety of eukaryotes%3B involved in the metabolism of xenobiotic compounds
chr5	3451742	3453424	+	DDB_G0289929	fmoD	belongs to the fmo family%3B similar to flavin-containing monooxygenases from a variety of eukaryotes%3B involved in the metabolism of xenobiotic compounds
chr5	3453668	3455281	+	DDB_G0289931	fmoE	belongs to the fmo family%3B similar to flavin-containing monooxygenases from a variety of eukaryotes%3B involved in the metabolism of xenobiotic compounds
chr5	3455388	3457016	-	DDB_G0289933	DDB_G0289933	NA
chr5	3457434	3460110	-	DDB_G0289935	gtf3C5	general transcription factor required for the initiation of transcription by RNA polymerase III
chr5	3460667	3463360	+	DDB_G0289937	DDB_G0289937	NA
chr5	3463581	3465887	-	DDB_G0289883	cupG	highly conserved protein family up-regulated by Ca2%2B%3B expressed throughout vegetative cells and in the cortex of aggregating cells
chr5	3466598	3467103	-	DDB_G0289983	kxcA_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene  %3Ca href%3D%22%2Fgene%2FDDB_G0289859%22%3E%3Ci%3EkxcA%3C%2Fi%3E%3C%2Fa%3E
chr5	3468286	3471204	+	DDB_G0289939	DDB_G0289939	conserved hypothetical Dictyostelium protein
chr5	3471284	3477219	-	DDB_G0289985	DDB_G0289985	similar to human protein KIAA0195%2C a transmembrane protein%3B contains 8 putative transmembrane domains
chr5	3478416	3479861	+	DDB_G0289941	DDB_G0289941	NA
chr5	3479964	3484889	-	DDB_G0289943	DDB_G0289943	conserved protein
chr5	3486480	3487388	+	DDB_G0289877	rps9	protein component of the small (40S) ribosomal subunit
chr5	3488380	3489241	+	DDB_G0289945	DDB_G0289945	NA
chr5	3490340	3495445	+	DDB_G0289947	DDB_G0289947	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr5	3495799	3500546	+	DDB_G0289949	DDB_G0289949	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr5	3500701	3501546	-	DDB_G0289885	sigF	regulated by the MADS-box transcription factor SrfA during development
chr5	3502780	3503206	-	DDB_G0289951	DDB_G0289951	NA
chr5	3505573	3508045	-	DDB_G0289953	DDB_G0289953	NA
chr5	3508916	3509780	-	DDB_G0289955	DDB_G0289955	NA
chr5	3510343	3510764	-	DDB_G0289957	DDB_G0289957	NA
chr5	3511088	3512671	+	DDB_G0289963	DDB_G0289963	NA
chr5	3515224	3518414	+	DDB_G0289987	DDB_G0289987	NA
chr5	3519269	3519516	+	DDB_G0290003	DDB_G0290003	NA
chr5	3520850	3521094	+	DDB_G0289989	DDB_G0289989	NA
chr5	3521273	3522475	-	DDB_G0289991	DDB_G0289991	NA
chr5	3523290	3525475	-	DDB_G0289993	DDB_G0289993	catalyzes the reaction acyl-CoA %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E trans-2%2C3-dehydroacyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr5	3525827	3527203	-	DDB_G0289995	DDB_G0289995	NA
chr5	3527673	3528128	-	DDB_G0289997	DDB_G0289997	NA
chr5	3529568	3530446	-	DDB_G0289999	DDB_G0289999	NA
chr5	3530853	3531707	-	DDB_G0290001	DDB_G0290001	NA
chr5	3532204	3537786	-	DDB_G0290005	DDB_G0290005	similar to myotubularin%2C a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3%2C5)-bi-phosphate
chr5	3538386	3539090	-	DDB_G0290007	DDB_G0290007	NA
chr5	3541529	3541835	+	DDB_G0290013	DDB_G0290013	NA
chr5	3542247	3542676	-	DDB_G0290015	grxA	glutathione-dependent electron donor involved in regulation of cell redox homeostasis
chr5	3543307	3543955	-	DDB_G0290017	DDB_G0290017	NA
chr5	3544279	3548237	+	DDB_G0290019	DDB_G0290019	NA
chr5	3549059	3552013	+	DDB_G0290021	DDB_G0290021	NA
chr5	3552302	3553313	+	DDB_G0290009	sr	catalyzes the reaction 7%2C8-dihydrobiopterin %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %3D sepiapterin %2B NADPH %2B H%3Csup%3E%2B%3C%2Fsup%3E%2C the final step in L-erythro-tetrahydrobiopterin (BH4) biosynthesis%2C a cofactor for aromatic amino acid oxidation%3Cbr%3E 
chr5	3553377	3555794	-	DDB_G0290023	gxcL	NA
chr5	3556440	3557443	+	DDB_G0290025	DDB_G0290025	contains one UBA-like domain and one DCUN1 domain%3B homolog of human DCUN1D1 and S. cerevisiae DCN1 (defective in cullin neddylation protein 1)%3B defects in DCUN1D1 may be a cause of squamous cell carcinomas
chr5	3557818	3558180	+	DDB_G0290027	DDB_G0290027	NA
chr5	3560404	3561703	-	DDB_G0290029	DDB_G0290029	similar to Apis mellifera predicted protein XM_394767.1
chr5	3562515	3563475	+	DDB_G0290031	DDB_G0290031	belongs to the ribosomal protein S8e family%3B ortholog of human TINP1 (TGF-beta-inducible nuclear protein 1) and S. cerevisiae NSA2%3B NSA2 (NOP seven associated 2) is involved in the biogenesis of the 60S ribosomal subunit
chr5	3563896	3566584	-	DDB_G0290051	DDB_G0290051	putative pseudogene%3B similar to a large gene family encoding FNIP repeat-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290067%22%3E%3Ci%3EcigB%3C%2Fi%3E%3C%2Fa%3E 
chr5	3567000	3567511	-	DDB_G0290053	tmem170	conserved protein
chr5	3567893	3569481	-	DDB_G0290055	uap1	catalyzes the reaction UTP %2B N-acetyl-alpha-D-glucosamine 1-phosphate %3D diphosphate %2B UDP-N-acetyl-D-glucosamine
chr5	3570445	3572064	-	DDB_G0290057	DDB_G0290057	NA
chr5	3572751	3573560	+	DDB_G0290011	ipi	NA
chr5	3573621	3574420	-	DDB_G0290033	dtymk	catalyzes the reaction dTMP %2B ATP %3C%3D%3E dTDP %2B ADP in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine deoxyribonucleotides
chr5	3574815	3578312	+	DDB_G0290035	DDB_G0290035	NA
chr5	3578349	3583122	-	DDB_G0290059	DDB_G0290059_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0290037%22%3EDDB_G0290037%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290063%22%3EDDB_G0290063%3C%2Fa%3E
chr5	3583640	3588326	-	DDB_G0290037	DDB_G0290037	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain
chr5	3588988	3593673	-	DDB_G0290061	DDB_G0290061	NA
chr5	3595858	3600601	-	DDB_G0290063	DDB_G0290063	conserved Dictyostelium protein%3B contains a putative N-terminal signal sequence%2C a C-terminal anchoring transmembrane domain and one EGF-like domain%3B enriched in gametes
chr5	3601688	3604966	-	DDB_G0290039	DDB_G0290039	NA
chr5	3605172	3605488	-	DDB_G0290041	DDB_G0290041	similar to D. purpureum protein
chr5	3605816	3607651	-	DDB_G0290043	DDB_G0290043	NA
chr5	3608057	3608344	+	DDB_G0290045	DDB_G0290045_ps	putative pseudogene%3B fragment%2C similar to UNC93-like protein MFSD11 family members %3Ca href%3D%22%2Fgene%2FDDB_G0291720%22%3EDDB_G0291720%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0291722%22%3EDDB_G0291722%3C%2Fa%3E
chr5	3609197	3609934	-	DDB_G0290047	DDB_G0290047_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0290067%22%3EcigB%3C%2Fa%3E family proteins
chr5	3610142	3610367	-	DDB_G0290065	DDB_G0290065	NA
chr5	3611605	3614136	+	DDB_G0290095	DDB_G0290095	NA
chr5	3614348	3616921	-	DDB_G0290073	DDB_G0290073	NA
chr5	3618710	3620743	-	DDB_G0290075	DDB_G0290075	protein phosphatase 2C is a serine%2Fthreonine specific protein phosphatase with broad substrate specificity and dependent on divalent cations (mainly manganese and magnesium) for its activity
chr5	3622051	3622479	+	DDB_G0290077	mlcB	light chain that binds to the neck region of myoB%3B contains two calcium-binding EF-hands
chr5	3623616	3627711	+	DDB_G0290079	pgtB	CAZy family GT2%2F4%3B disruption of this gene results in abolished spore coat lectin-binding and renders spores hypersensitive to plasmolysis 
chr5	3627939	3630336	-	DDB_G0290081	sort1	ortholog of S. cerevisiae PEP1 and mammalian sortilin%2C a sorting receptor of the Golgi apparatus
chr5	3631373	3631984	-	DDB_G0290083	DDB_G0290083	NA
chr5	3632186	3633463	-	DDB_G0290071	sigG	regulated by the MADS-box transcription factor SrfA during development
chr5	3634285	3635892	+	DDB_G0290097	DDB_G0290097	NA
chr5	3636614	3641371	+	DDB_G0290085	DDB_G0290085	NA
chr5	3642812	3645107	-	DDB_G0290067	cigB	NA
chr5	3645353	3646807	-	DDB_G0349444	DDB_G0349444	putative pseudogene%3B similar to a large gene family encoding FNIP repeat-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290067%22%3E%3Ci%3EcigB%3C%2Fi%3E%3C%2Fa%3E 
chr5	3647628	3648401	-	DDB_G0290087	vps2A	putative ortholog of human CHMP2A (Chromatin Modifying Protein 2A) and yeast DID4 (Doa4-Independent Degradation)%2C component of the ESCRT-III complex (endosomal sorting complex required for transport)
chr5	3648784	3650227	-	DDB_G0290089	DDB_G0290089	involved in fatty acid biosynthesis%3B catalyzes the conversion of malonyl-CoA to acetyl-CoA
chr5	3651511	3652395	+	DDB_G0290069	pitA	NA
chr5	3652594	3653029	-	DDB_G0290091	rpl22a	protein component of the large (60S) ribosomal subunit
chr5	3653634	3654567	-	DDB_G0290093	DDB_G0290093	NA
chr5	3654997	3655670	-	DDB_G0290105	DDB_G0290105	similar to human zinc finger protein 207 (ZNF207)
chr5	3656306	3658157	+	DDB_G0290103	elp3	similar to ELP3%2C the histone acetyltransferase subunit of the subunit of the RNA polymerase II elongator complex
chr5	3658887	3658960	+	DDB_G0295253	tRNA-Val-UAC-4	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3660287	3660360	+	DDB_G0295255	tRNA-Val-UAC-5	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3660841	3662716	-	DDB_G0290107	DDB_G0290107	contains 9 putative transmembrane domains%3B conserved in Polysphondylium pallidum and D. purpureum
chr5	3664675	3667628	+	DDB_G0290101	DDB_G0290101	putative pseudogene%3B similar to a large gene family encoding FNIP repeat-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290067%22%3E%3Ci%3EcigB%3C%2Fi%3E%3C%2Fa%3E 
chr5	3667946	3670241	+	DDB_G0290109	DDB_G0290109	NA
chr5	3671708	3673351	+	DDB_G0290111	adhfe1	conserved Fe-containing alcohol dehydrogenase
chr5	3675019	3677951	+	DDB_G0290113	DDB_G0290113	member of a large Dictyostelium gene family containing FNIP repeats
chr5	3679131	3681431	+	DDB_G0290119	DDB_G0290119_ps	putative pseudogene%3B FNIP repeat family protein
chr5	3683216	3685745	+	DDB_G0290121	purD	bifunctional enzyme of the %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis pathway%2C contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities
chr5	3685883	3688399	-	DDB_G0290125	DDB_G0290125	NA
chr5	3689897	3692063	+	DDB_G0290127	DDB_G0290127	contains an N-terminal F-box domain and eight WD40 repeats
chr5	3692217	3693170	-	DDB_G0290123	phbA	ortholog of the yeast Phb1p and other prohibitins that are inner mitochondrial membrane chaperones that stabilize newly synthesized proteins%3B also suggested to play a role in cell senescence
chr5	3693576	3693648	+	DDB_G0295257	tRNA-Arg-UCU-11	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3694123	3694640	+	DDB_G0290129	DDB_G0290129_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr5	3695903	3697426	+	DDB_G0290139	DDB_G0290139	contains a putative signal peptide
chr5	3697750	3698923	+	DDB_G0290133	DDB_G0290133	NA
chr5	3699370	3699640	-	DDB_G0290135	DDB_G0290135	NA
chr5	3700826	3701808	+	DDB_G0290137	DDB_G0290137	NA
chr5	3702246	3703492	+	DDB_G0290155	DDB_G0290155	NA
chr5	3703699	3704776	+	DDB_G0290151	DDB_G0290151	NA
chr5	3704919	3705652	-	DDB_G0290143	DDB_G0290143	NA
chr5	3706333	3707026	+	DDB_G0290141	rps17	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S17 homolog
chr5	3707194	3710571	-	DDB_G0290145	DDB_G0290145	NA
chr5	3711190	3711628	+	DDB_G0290147	DDB_G0290147	NA
chr5	3712218	3713933	-	DDB_G0290153	DDB_G0290153	contains 12 putative transmembrane domains
chr5	3717777	3719423	-	DDB_G0290157	pkgB	AGC group protein serine%2Fthreonine kinase%3B cAMP-activated protein kinase involved in morphogenesis during multicellular development
chr5	3722127	3723282	+	DDB_G0290161	miox	catalyzes the reaction myo-inositol %2B O%3Csup%3E2%3C%2Fsup%3E %3D D-glucuronate %2B H%3Csup%3E2%3C%2Fsup%3EO
chr5	3723872	3726068	+	DDB_G0290163	tom1	contains a VHS domain and a GAT domain%3B amino terminus is similar to mammalian TOM1 protein%2C which is involved in intracellular protein transport
chr5	3726519	3729302	-	DDB_G0290165	bzpR	NA
chr5	3729972	3730231	-	DDB_G0290167	DDB_G0290167	NA
chr5	3730693	3732843	-	DDB_G0290169	bzpO	NA
chr5	3733307	3735838	-	DDB_G0290171	bzpS	NA
chr5	3736207	3738432	-	DDB_G0290173	bzpI	NA
chr5	3738710	3740039	-	DDB_G0290175	DDB_G0290175	contains a predicted signal peptide and a C-teminal transmembrane domain%3B small gene family in D. discoideum and D. purpureum
chr5	3740464	3741633	-	DDB_G0290177	DDB_G0290177	contains an N-terminal signal sequence and a C-terminal transmembrane domain%3B underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr5	3742663	3745923	-	DDB_G0290179	ube3a	conserved E3 ubiquitin-protein ligase that in mammals accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
chr5	3746723	3749553	-	DDB_G0290181	DDB_G0290181	similar to %3Ci%3ES.cerevisiae%3C%2Fi%3E RRP5 and animal PDCD11 (Programmed cell death protein 11)
chr5	3749810	3751153	+	DDB_G0290183	DDB_G0290183	NA
chr5	3751345	3753712	-	DDB_G0290159	phg1c	9 transmembrane protein
chr5	3754060	3755076	-	DDB_G0290185	crlF	similar to serpentine%2FG-protein coupled receptors%3B contains 7 putative transmembrane domains
chr5	3761819	3761892	+	DDB_G0295259	tRNA-Val-UAC-6	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3764090	3765595	+	DDB_G0290241	DDB_G0290241_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr5	3766463	3767577	+	DDB_G0290189	DDB_G0290189	NA
chr5	3768414	3768893	-	DDB_G0290243	act39_ps	putative pseudogene%3B contains a partial actin domain
chr5	3769697	3772385	+	DDB_G0290245	psiC	similar to dicA1%3B contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C 3 Dictyostelium (CTDC) repeats%3B expressed in prespore cells
chr5	3772467	3773465	-	DDB_G0295739	DDB_G0295739	has similarity to bacterial homoserine kinases or serine proteases
chr5	3774102	3774572	+	DDB_G0290191	DDB_G0290191	NA
chr5	3774767	3778950	-	DDB_G0290193	DDB_G0290193	NA
chr5	3779790	3780920	-	DDB_G0290195	DDB_G0290195	NA
chr5	3781653	3783703	+	DDB_G0290197	DDB_G0290197	similar to plant and fungi NADH dehydrogenases such as S. cerevisiae NDE1 and NDE2%2C the external mitochondrial NADH dehydrogenases that catalyze the oxidation of cytosolic NADH
chr5	3783788	3784438	-	DDB_G0290199	DDB_G0290199	NA
chr5	3784827	3786460	+	DDB_G0290201	DDB_G0290201	NA
chr5	3786795	3788047	+	DDB_G0290239	DDB_G0290239	NA
chr5	3789362	3792750	+	DDB_G0290247	DDB_G0290247	NA
chr5	3792983	3793910	+	DDB_G0290203	DDB_G0290203	NA
chr5	3794310	3795191	+	DDB_G0290205	DDB_G0290205	NA
chr5	3795307	3796614	-	DDB_G0290207	mdhA	catalyzes the reaction malate %2B NAD %3C%3D%3E oxaloacetate %2B NADH
chr5	3797080	3797974	-	DDB_G0290209	med10	ortholog of the mediator of RNA polymerase II transcription subunit 10%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr5	3798435	3802327	+	DDB_G0290211	DDB_G0290211	NA
chr5	3802462	3804572	-	DDB_G0290213	vps45	putative ortholog of VPS45%2C involved in vacuolar protein sorting
chr5	3805894	3809568	+	DDB_G0290215	DDB_G0290215	NA
chr5	3809656	3811671	-	DDB_G0290217	glb1	belongs to glycoside hydrolase family 35%3B hydrolyzes terminal non-reducing beta-D-galactose residues in beta-D-galactoside%3B has a signal peptide
chr5	3812159	3813253	-	DDB_G0290219	DDB_G0290219	NA
chr5	3814762	3815796	+	DDB_G0290221	arv1	ortholog of in S. cerevisiae%2C ARV1%2C that transports glycosylphosphatidylinositol intermediates into the ER lumen%3B required for normal intracellular sterol distribution and for sphingolipid metabolism and required for viability in the absence of ARE2 (ACAT-related enzyme 2) 
chr5	3816109	3817002	+	DDB_G0290223	DDB_G0290223	putative 22 kDa peroxisomal membrane protein that may be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane
chr5	3818443	3820972	+	DDB_G0290187	hspH	regulated by the MADS-box transcription factor SrfA during development
chr5	3821076	3823946	-	DDB_G0290249	DDB_G0290249	NA
chr5	3824091	3825545	-	DDB_G0290225	DDB_G0290225	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity%3B enriched in gametes
chr5	3826055	3827450	-	DDB_G0290251	DDB_G0290251_ps	putative pseudogene%3B related to the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr5	3827990	3830121	-	DDB_G0290227	npl4	ortholog of NPL4%3B together with ufd1 and cdcD%2C  involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation 
chr5	3830807	3832161	+	DDB_G0290229	DDB_G0290229	catalyzes the reaction CTP %2B choline phosphate %3C%3D%3E diphosphate %2B CDPcholine
chr5	3832338	3834086	-	DDB_G0290231	DDB_G0290231	NA
chr5	3834823	3837906	+	DDB_G0290233	mgp1	involved in the regulation of filopodium formation and the contractile vacuole network
chr5	3838039	3838161	-	DDB_G0290235	DDB_G0290235	NA
chr5	3838664	3839742	+	DDB_G0290237	acbd6	ortholog of mammalian ACBD6
chr5	3840207	3843233	-	DDB_G0290253	nhe4	NA
chr5	3845621	3845693	+	DDB_G0295261	tRNA-Met-CAU-14	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3846563	3846953	+	DDB_G0290255	DDB_G0290255	NA
chr5	3847142	3849100	+	DDB_G0290273	DDB_G0290273	NA
chr5	3849199	3850149	-	DDB_G0290275	DDB_G0290275	NA
chr5	3850328	3853714	-	DDB_G0290359	DDB_G0290359	the N-terminal half of the protein is very similar to human EFR3A (Protein EFR3 homolog A)%3B similar to %3Ci%3ED. purpureum%3C%2Fi%3E protein
chr5	3853979	3855303	+	DDB_G0290277	nudt19	ortholog of human NUDT19%2C a Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters
chr5	3856720	3857913	-	DDB_G0290279	dgat2	conserved  diglyceride acyltransferase most similar to U. ramanniana DGAT2B and H. sapiens DGAT2%3B catalyzing the reaction: acyl-CoA %2B 1%2C2-diacylglycerol %3D CoA %2B triacylglycerol 
chr5	3858234	3859007	-	DDB_G0290281	drpp21	ortholog of RPR2%2C a subunit of nuclear RNase P%2C which cleaves tRNA precursors to generate mature 5%27 ends
chr5	3859451	3863001	-	DDB_G0290283	DDB_G0290283	NA
chr5	3865328	3867890	+	DDB_G0290285	DDB_G0290285	NA
chr5	3868716	3870914	+	DDB_G0290349	DDB_G0290349	NA
chr5	3871677	3873765	+	DDB_G0290361	DDB_G0290361_ps	putative pseudogene%3B similar to a %3Ci%3ED. discoideum%3C%2Fi%3E gene family%2C including the just upstream %3Ca href%3D%22%2Fgene%2FDDB_G0290285%22%3EDDB_G0290285%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290349%22%3EDDB_G0290349%3C%2Fa%3E
chr5	3875194	3878028	+	DDB_G0290267	gefO	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr5	3879007	3879466	+	DDB_G0290363	sybB	very similar to sybA%2C a gene that is regulated by the MADS-box transcription factor SrfA during development
chr5	3881786	3883666	+	DDB_G0290365	ctdspl2	contains a C-terminal putative phosphatase domain of an eukaryotic protein family including Dullard and the NLI (Nuclear Lim Interactor) interacting factor
chr5	3884030	3890046	+	DDB_G0290289	DDB_G0290289	NA
chr5	3890601	3893277	+	DDB_G0290351	DDB_G0290351	NA
chr5	3893526	3894095	-	DDB_G0290291	DDB_G0290291	similar to MAPEG (membrane associated proteins in eicosanoid and glutathione metabolism) family%2C which includes microsomal glutathione S-transferase II and 5-lipoxygenase activating protein%3B expressed in prespore cells
chr5	3895673	3897403	+	DDB_G0294561	cyp514A2	NA
chr5	3898353	3899256	+	DDB_G0290271	cfr_ps1	putative pseudogene%3B highly similar to cfr (Cell Fusion Related) genes (cell surface glycoprotein GP138)
chr5	3899689	3900311	-	DDB_G0290293	colA_ps2	putative pseudogene%3B small fragment similar to the large colossin A gene %3Ca href%3D%22%2Fgene%2FDDB_G0279833%22%3EcolA%3C%2Fa%3E
chr5	3901077	3903576	+	DDB_G0290257	cfrA	NA
chr5	3904303	3904993	-	DDB_G0290367	colA_ps1	putative pseudogene%3B small fragment similar to the large colossin A gene %3Ca href%3D%22%2Fgene%2FDDB_G0279833%22%3EcolA%3C%2Fa%3E
chr5	3906804	3909269	+	DDB_G0290259	cfrB	NA
chr5	3911024	3913594	+	DDB_G0290261	cfrC	NA
chr5	3914845	3917432	+	DDB_G0290265	cfrD	NA
chr5	3918589	3919095	+	DDB_G0290269	cfr_ps2	putative pseudogene%3B highly similar to cfr (Cell Fusion Related) genes (cell surface glycoprotein GP138)
chr5	3919905	3920270	+	DDB_G0295629	mrpRNA	RNA component of the RNase MRP ribonucleoprotein%2C which is involved in processing of rRNA in the nucleus and replication of mitochondrial DNA
chr5	3920410	3921134	-	DDB_G0290295	DDB_G0290295	NA
chr5	3921390	3922556	+	DDB_G0290297	xrcc2	putative ortholog of XRCC2%2C which is involved in double-strand break repair%3B interacts with RAD51
chr5	3922756	3923118	-	DDB_G0290299	DDB_G0290299	NA
chr5	3923457	3927173	-	DDB_G0290301	DDB_G0290301	NA
chr5	3929845	3932459	+	DDB_G0290303	bzpP	NA
chr5	3933600	3934867	-	DDB_G0290263	pho2a	catalytic subunit of protein phosphatase 2A%2C  composed of a catalytic subunit (pho2A)%2C a regulatory subunit (phr2AB) and a scaffold subunit (pppA)%3B an additional regulatory B56 (psrA) subunit has been identified 
chr5	3936242	3937957	+	DDB_G0290305	DDB_G0290305	NA
chr5	3938585	3940056	+	DDB_G0290307	DDB_G0290307	contains three RRM domains%3B homolog of ELAVL1 (embryonic lethal%2C abnormal vision-like 1)
chr5	3940357	3941059	-	DDB_G0290309	DDB_G0290309	NA
chr5	3942085	3943971	-	DDB_G0290311	DDB_G0290311	NA
chr5	3944329	3946272	+	DDB_G0290313	DDB_G0290313	NA
chr5	3946402	3947228	-	DDB_G0290315	rpl23	protein component of the large (60S) ribosomal subunit
chr5	3947753	3950272	-	DDB_G0290317	psiJ	contains a PA14 (anthrax protection antigen) domain and 6 Dictyostelium (CTDC) repeats
chr5	3952440	3952895	+	DDB_G0290319	DDB_G0290319	NA
chr5	3953111	3955504	-	DDB_G0290321	DDB_G0290321	NA
chr5	3955755	3958028	-	DDB_G0290323	DDB_G0290323	NA
chr5	3958340	3965920	-	DDB_G0290325	espl1	caspase-like protease also called separin (ESP1)%2C which plays a central role in sister chromosome segregation in yeast%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E espl1 is highly similar to separase (aka separin)%2C a widely-conserved peptidase which cleaves the rad21%2Fssc1 non-SMC subunit of cohesin rings remaining at the centromere at metaphase%2C allowing the sister chromatids to separate. Consistent with this homology%2C espl1 is overexpressed fourfold (p%3C6e-14) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted. Most genes with roles in S-phase or mitosis are overexpressed in this strain%2C and most of the overexpressed genes have identifiable cell cycle functions. espl1 also shows the developmental time course most typical of cell cycle genes.%3Cbr%3E The separase inhibitor securin%2C conserved between yeast and humans%2C which is broken down at the metaphase%2Fanaphase junction under control of the spindle checkpoint%2C is not recognizable in Dicty. Securin is also unrecognizable plants%2C however%2C whle other components of the spindle checkpoint%2C such as mad2%2C bub1%2C bub3%2C and cdc20%2C are recognizable in Dicty. These show overexpression factors (and developmental time courses) similar to espl1. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E
chr5	3966621	3967848	-	DDB_G0290327	gtf2a1	encodes the two largest subunits of TFIIA%3B important but not essential for transcriptional activation%2C functioning as either an antirepressor or a coactivator
chr5	3968559	3969464	-	DDB_G0290329	DDB_G0290329	NA
chr5	3969916	3971699	-	DDB_G0290331	ssrp1	ortholog of the SSRP1 component of the FACT complex%2C a heterodimer of ssrp1 and spt16%3B the FACT complex is a general chromatin factor that acts to reorganize nucleosomes%2C involved in multiple processes that require DNA as a template such as mRNA elongation%2C DNA replication and DNA repair
chr5	3973178	3975140	+	DDB_G0290333	DDB_G0290333	belongs to the peptidase S53 family%3B similar to P. polycephalum physarolisin%3B contains a predicted signal peptide
chr5	3975307	3976386	+	DDB_G0290335	DDB_G0290335	NA
chr5	3976953	3983217	+	DDB_G0290369	DDB_G0290369	NA
chr5	3983670	3986235	+	DDB_G0290337	DDB_G0290337	NA
chr5	3987062	3987157	-	DDB_G0295267	tRNA-Ala-UGC-8	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr5	3987458	3988839	+	DDB_G0290339	ugt1	CAZy family GT28%3B contains a glycosyltransferase 28  domain and a partial MurG acetylglucosaminetransferase domain
chr5	3989030	3989766	-	DDB_G0290341	DDB_G0290341	similar to S. cerevisiae SFT2%3B contains 4 putative transmembrane domains%3B similar to D. purpureum protein
chr5	3991148	3992077	+	DDB_G0290371	DDB_G0290371	contains one putative transmembrane domain
chr5	3992463	3992921	+	DDB_G0290343	sodE	very similar to human SOD1%2C defects in which cause familial amyotrophic lateral sclerosis (ALS)%3B belongs to the Cu-Zn superoxide dismutase family
chr5	3993062	3998128	-	DDB_G0290373	DDB_G0290373	NA
chr5	4001426	4002869	-	DDB_G0290347	DDB_G0290347	similar to D. purpureum protein
chr5	4004269	4005300	+	DDB_G0290375	DDB_G0290375_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr5	4005478	4005549	+	DDB_G0295263	tRNA-Asp-GUC-19	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr5	4006163	4006568	+	DDB_G0290447	DDB_G0290447_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr5	4008116	4011078	-	DDB_G0290377	agnB	NA
chr5	4011706	4012887	-	DDB_G0290379	DDB_G0290379	NA
chr5	4013215	4015500	+	DDB_G0290381	DDB_G0290381	NA
chr5	4015567	4016572	-	DDB_G0290449	DDB_G0290449	NA
chr5	4017007	4017336	+	DDB_G0290383	DDB_G0290383	NA
chr5	4019200	4020229	+	DDB_G0290387	DDB_G0290387	similar to D. purpureum proteins%3B small gene family in both species
chr5	4020336	4027033	-	DDB_G0290389	ascc3	ortholog of human ASCC3%2C part of the TRIP4 complex  that enhances activation of NF-kappa-B%2C SRF%2C and AP1
chr5	4027524	4028450	-	DDB_G0290391	DDB_G0290391	NA
chr5	4028814	4029317	-	DDB_G0290393	DDB_G0290393	similar to yeast ERG28%2C an endoplasmic reticulum protein involved in ergosterol biosynthesis%3B contains 3 putative transmembrane domains
chr5	4029574	4030716	-	DDB_G0290395	DDB_G0290395	NA
chr5	4031914	4033830	+	DDB_G0290397	fthS	catalyzes the reaction ATP %2B formate %2B tetrahydrofolate %3C%3D%3E ADP %2B phosphate %2B N10-formyl-H%3Csub%3E4%3C%2Fsub%3EF in various biosynthetic pathways%3B in plants and in Dictyostelium%2C this is a monofunctional enzyme%2C while in yeast and in metazoan the same enzyme has two additional activities%2C encoded by %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283121%22%3E%3Ci%3EDDB_G0283121%3C%2Fi%3E%3C%2Fa%3E
chr5	4034032	4037497	-	DDB_G0290399	DDB_G0290399	NA
chr5	4038671	4040900	+	DDB_G0290401	DDB_G0290401	phosphorylates (R)-pantothenate to (R)-4%27-phosphopantothenate
chr5	4041398	4042036	+	DDB_G0290403	DDB_G0290403	NA
chr5	4043666	4046544	+	DDB_G0290405	tpsC	CAZy family GT20%3B contains an N-terminal glycosyltransferase domain and a C-terminal trehalose-phosphatase domain
chr5	4047054	4047941	+	DDB_G0290407	rabO	NA
chr5	4048204	4050042	+	DDB_G0290409	DDB_G0290409	contains a putative signal peptide
chr5	4050217	4051059	-	DDB_G0290411	DDB_G0290411	NA
chr5	4053731	4057481	+	DDB_G0290415	DDB_G0290415	NA
chr5	4058161	4060793	+	DDB_G0290451	shkE	member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily%3B contains a C-terminal SH2 (Src homology 2) domain
chr5	4060970	4062304	-	DDB_G0290417	chid1	conserved protein
chr5	4062441	4062834	-	DDB_G0290419	DDB_G0290419	NA
chr5	4063431	4065691	-	DDB_G0290421	DDB_G0290421	NA
chr5	4067949	4069691	+	DDB_G0290423	DDB_G0290423	contains 11 putative transmembrane domains
chr5	4070123	4071429	+	DDB_G0290425	DDB_G0290425	NA
chr5	4071585	4073431	-	DDB_G0290453	usp12	ortholog of H. sapiens USP12 and S. cerevisiae UBP13
chr5	4073745	4076192	+	DDB_G0348183	DDB_G0348183	NA
chr5	4076581	4077480	+	DDB_G0348184	DDB_G0348184	NA
chr5	4077605	4079046	-	DDB_G0290457	DDB_G0290457	NA
chr5	4079741	4080955	+	DDB_G0290459	DDB_G0290459	NA
chr5	4081599	4082234	+	DDB_G0290461	DDB_G0290461	NA
chr5	4082312	4082746	-	DDB_G0290463	DDB_G0290463	NA
chr5	4083295	4085606	+	DDB_G0290465	DDB_G0290465	conserved hypothetical 695 aa Dictyostelium protein%3B centrosomal component
chr5	4086338	4095068	+	DDB_G0290467	pks27	putative type I iterative polyketide synthase
chr5	4095634	4104349	+	DDB_G0290469	pks28	putative type I iterative polyketide synthase
chr5	4104623	4105366	+	DDB_G0295479	DDB_G0295479	similar to polyketide synthases but only 179 amino acids long%3B other polyketide synthase genes encode proteins of about 3%2C000 amino acids
chr5	4105828	4106886	-	DDB_G0290471	DDB_G0290471	member of the TKL (tyrosine kinase-like) group%3B belongs to the ARK (ankyrin repeat-containing kinase) family%2C although it does not contain ankyrin repeats%3B does not contain the consensus sequences required for kinase function
chr5	4107607	4109571	-	DDB_G0290473	DDB_G0290473	NA
chr5	4110262	4110723	+	DDB_G0290475	DDB_G0290475	NA
chr5	4111634	4112800	-	DDB_G0290443	DDB_G0290443	contains one C-terminal predicted transmembrane domain
chr5	4113138	4114100	-	DDB_G0290427	DDB_G0290427	NA
chr5	4115465	4115860	+	DDB_G0290429	DDB_G0290429	NA
chr5	4116429	4117886	+	DDB_G0290431	DDB_G0290431	NA
chr5	4118281	4123371	-	DDB_G0290433	DDB_G0290433	NA
chr5	4124662	4127869	+	DDB_G0290435	DDB_G0290435	NA
chr5	4128169	4128924	+	DDB_G0290437	DDB_G0290437	NA
chr5	4129372	4133077	-	DDB_G0290439	gacW	NA
chr5	4134020	4135372	+	DDB_G0290441	DDB_G0290441	NA
chr5	4140984	4143263	+	DDB_G0290487	DDB_G0290487	NA
chr5	4143852	4145798	+	DDB_G0290489	DDB_G0290489	NA
chr5	4146073	4146775	-	DDB_G0290491	DDB_G0290491	very similar to atg8 and also similar to human microtubule-associated protein 1 light chain 3 alpha (MAP1LC3A)
chr5	4148104	4150968	+	DDB_G0290493	gxcHH	NA
chr5	4151099	4151800	-	DDB_G0290495	DDB_G0290495	NA
chr5	4152368	4154242	-	DDB_G0290497	DDB_G0290497	similar to D. purpureum protein
chr5	4156073	4157022	+	DDB_G0290499	slmo	conserved protein%3B in D. melanogaster%2C lack of SLMO leads to defects in locomotor behavior and die during larval development%3B contains a PRELI%2FMSF1 domain
chr5	4157355	4159334	+	DDB_G0290501	xpnpep1	probable Xaa-Pro aminopeptidase 1%2C that releases any N-terminal amino acid%2C including proline%2C that is linked to proline%2C even from a dipeptide or tripeptide
chr5	4159418	4164037	-	DDB_G0290503	DDB_G0290503	NA
chr5	4164699	4166676	-	DDB_G0290505	DDB_G0290505	NA
chr5	4167405	4169617	-	DDB_G0290507	DDB_G0290507	NA
chr5	4170905	4173877	+	DDB_G0290647	DDB_G0290647	similar to mammalian XPR1%2C which may confer susceptibility to infection with murine leukaemia viruses%3B also similar to yeast SYG1%2C a G-protein associated signal transduction protein%2C and plant PHO1%2C that may be involved in phosphate transport 
chr5	4173965	4175377	-	DDB_G0290509	cepC	localizes to the centrosomal core structure
chr5	4175909	4179072	+	DDB_G0290513	DDB_G0290513	NA
chr5	4179788	4197485	+	DDB_G0290641	DDB_G0290641	NA
chr5	4199032	4199175	+	DDB_G0290519	DDB_G0290519	NA
chr5	4200324	4201616	-	DDB_G0290521	DDB_G0290521	NA
chr5	4202596	4204042	+	DDB_G0290649	DDB_G0290649	conserved RNA binding motif protein%3B ortholog of mammalian RBM22 and similar to yeast ECM2%2C a pre-mRNA splicing factor
chr5	4204192	4205504	-	DDB_G0290523	DDB_G0290523	NA
chr5	4206508	4209622	+	DDB_G0290651	DDB_G0290651	NA
chr5	4209815	4211793	-	DDB_G0290483	abcE1	consists of two ABC domains and lacks a transmembrane domain
chr5	4212337	4213611	-	DDB_G0290525	DDB_G0290525	NA
chr5	4214740	4217137	-	DDB_G0290527	DDB_G0290527	NA
chr5	4217898	4219816	-	DDB_G0290529	cpnE	Ca(2%2B)-dependent phospholipid-binding protein%3B contains two C2 domains and a VWFA domain.
chr5	4220163	4225515	-	DDB_G0290653	DDB_G0290653	NA
chr5	4228089	4228462	+	DDB_G0290531	DDB_G0290531	NA
chr5	4229551	4230435	+	DDB_G0290533	DDB_G0290533	NA
chr5	4230498	4232233	-	DDB_G0290479	hydA	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr5	4232732	4234371	-	DDB_G0290535	DDB_G0290535	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr5	4235159	4236795	+	DDB_G0290537	DDB_G0290537	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr5	4236850	4237783	-	DDB_G0290539	DDB_G0290539	NA
chr5	4238133	4239878	-	DDB_G0290541	DDB_G0290541	NA
chr5	4241124	4241362	+	DDB_G0290655	DDB_G0290655	NA
chr5	4241742	4242468	+	DDB_G0290657	DDB_G0290657	NA
chr5	4242895	4243881	-	DDB_G0290543	DDB_G0290543	NA
chr5	4245577	4247814	+	DDB_G0290545	DDB_G0290545	NA
chr5	4248317	4249423	-	DDB_G0290547	DDB_G0290547	NA
chr5	4250883	4252034	+	DDB_G0290549	DDB_G0290549	NA
chr5	4252151	4256182	-	DDB_G0290551	rblA	putative ortholog of Retinoblastoma protein (Rb)%2C which inhibits progression from G1 to S phase of the cell cycle through interactions with the E2F family of transcription factors
chr5	4257563	4261596	+	DDB_G0290481	talA	The %3Cb%3EAX4%3C%2Fb%3E talin gene has a confirmed stop codon (R. Kay%2C private communication) that terminates the protein after residue 1%2C279%3B immunohistochemistry shows the presence of a very faint truncated talin (A. Mueller-Taubenberger%2C private communication)%3Cbr%3E %3Cb%3EAX2%3C%2Fb%3E talin is the full length homolog of mammalian talin  and other proteins of the band 4.1 superfamily%3B all functional data is derived from AX2%3B involved in cell-substrate adhesion and cytokinesis%3B the AX2 protein sequence is available from the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FTalA%22%3ECommunity Annotation Page%3C%2Fa%3E.
chr5	4265295	4266800	-	DDB_G0290553	DDB_G0290553	NA
chr5	4267110	4268820	+	DDB_G0290555	DDB_G0290555	NA
chr5	4269452	4271689	+	DDB_G0290557	DDB_G0290557	NA
chr5	4272924	4275001	-	DDB_G0290559	DDB_G0290559	NA
chr5	4275359	4277286	-	DDB_G0290561	DDB_G0290561_ps	putative pseudogene%3B similar to a family of genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290679%22%3EDDB_G0290679%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290559%22%3EDDB_G0290559%3C%2Fa%3E
chr5	4277976	4280282	+	DDB_G0290563	cupH	highly similar to cupG and other calcium up-regulated genes
chr5	4280779	4280850	-	DDB_G0267212	DDB_G0267212_RTE	Fused fragments of the DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr5	4281044	4281261	-	DDB_G0349111	hdaC_ps4	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0280195%22%3E%3Ci%3EhdaC%3C%2Fi%3E%3C%2Fa%3E
chr5	4282644	4284239	-	DDB_G0290565	DDB_G0290565_ps	NA
chr5	4284701	4286155	-	DDB_G0290567	DDB_G0290567_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0290559%22%3EDDB_G0290559%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290571%22%3EDDB_G0290571%3C%2Fa%3E
chr5	4286973	4287945	+	DDB_G0290659	sdrA	NA
chr5	4288392	4290518	-	DDB_G0290569	DDB_G0290569_ps	putative pseudogene%3B very similar to FNIP-domain containing protein coding genes %3Ca href%3D%22%2Fgene%2FDDB_G0290571%22%3E DDB_G0290571%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290571%22%3E DDB_G0290571%3C%2Fa%3E and others
chr5	4292030	4294250	-	DDB_G0290571	DDB_G0290571	contains 7 FNIP domains%3B conserved in Dictyostelium%3B similar to D. purpureum protein
chr5	4295576	4296919	-	DDB_G0290573	DDB_G0290573	conserved in Dictyostelids
chr5	4299544	4301062	+	DDB_G0290575	DDB_G0290575	NA
chr5	4301494	4302722	-	DDB_G0290577	dnase2	mammals have two lysosomal DNase II enzymes while %3Ci%3EDictyosyelium%3C%2Fi%3E has just one DNase II%3B catalyzes endonucleolytic cleavage of preferably double-stranded DNA to nucleoside 3%27-phosphates and 3%27-phosphooligonucleotide end-products.
chr5	4303636	4304797	+	DDB_G0290645	DDB_G0290645	NA
chr5	4305581	4308334	+	DDB_G0290663	DDB_G0290663	NA
chr5	4310280	4310895	+	DDB_G0290579	DDB_G0290579	NA
chr5	4312004	4313332	+	DDB_G0290665	gtaX	has 21 amino acids between the two CX2C motifs
chr5	4313752	4315264	-	DDB_G0290667	DDB_G0290667	NA
chr5	4316139	4317321	-	DDB_G0290669	mcfW	belongs to the substrate carrier proteins that are involved in energy transfer%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr5	4317912	4319104	+	DDB_G0290671	rabggtb	catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC%2C -XCXC and -CCXX C-terminal%3B forms a hetero-dimer with the %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0269570%22%3E%3Ci%3Ealpha%3C%2Fi%3E%3C%2Fa%3E subunit
chr5	4319294	4319461	-	DDB_G0290583	DDB_G0290583	NA
chr5	4319962	4320132	-	DDB_G0290585	DDB_G0290585	NA
chr5	4321079	4321444	-	DDB_G0290637	DDB_G0290637	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0294573%22%3E%3Ci%3EDDB_G0294573%3C%2Fi%3E%3C%2Fa%3E
chr5	4322112	4324310	-	DDB_G0290587	DDB_G0290587	similar to D. purpureum protein
chr5	4325235	4325507	-	DDB_G0290589	DDB_G0290589	NA
chr5	4327797	4334132	-	DDB_G0290591	DDB_G0290591	NA
chr5	4335292	4335824	+	DDB_G0290593	DDB_G0290593	conserved hypothetical protein
chr5	4337348	4338125	+	DDB_G0290595	DDB_G0290595	NA
chr5	4338558	4339997	+	DDB_G0290597	DDB_G0290597	NA
chr5	4340691	4341961	+	DDB_G0290673	DDB_G0290673	NA
chr5	4342512	4343347	+	DDB_G0290675	DDB_G0290675	contains 2 putative transmembrane domains
chr5	4343609	4343976	-	DDB_G0290599	DDB_G0290599	conserved in fungi
chr5	4344171	4345073	+	DDB_G0349319	DDB_G0349319	NA
chr5	4345695	4346598	+	DDB_G0349321	DDB_G0349321	NA
chr5	4347032	4352619	+	DDB_G0290677	DDB_G0290677	NA
chr5	4352727	4354592	-	DDB_G0290603	DDB_G0290603	NA
chr5	4356438	4357592	+	DDB_G0290605	DDB_G0290605	NA
chr5	4358106	4360111	+	DDB_G0290679	DDB_G0290679	NA
chr5	4360447	4363508	+	DDB_G0290607	DDB_G0290607_ps	putative pseudogene%3B similar to FNIP domain-containing proteins
chr5	4365656	4367557	+	DDB_G0290681	DDB_G0290681_ps	putative pseudogene%3B similar to FNIP domain-containing proteins
chr5	4368520	4370357	+	DDB_G0290683	DDB_G0290683_ps	putative pseudogene%3B similar to FNIP domain-containing proteins
chr5	4370850	4373203	+	DDB_G0290613	DDB_G0290613	NA
chr5	4375423	4377665	+	DDB_G0290617	chtB	contains 6 FNIP repeats
chr5	4378104	4380044	+	DDB_G0290639	DDB_G0290639	NA
chr5	4380155	4382317	-	DDB_G0290619	DDB_G0290619	similar to D. purpureum protein
chr5	4383355	4386337	-	DDB_G0290621	DDB_G0290621	member of the TKL (tyrosine kinase-like) group of protein kinases
chr5	4387215	4389650	+	DDB_G0290623	DDB_G0290623	NA
chr5	4389816	4391535	-	DDB_G0290625	DDB_G0290625	contains one B-box zinc finger domain and 4 FNIP repeats
chr5	4392045	4394048	-	DDB_G0290627	DDB_G0290627	NA
chr5	4394537	4397916	-	DDB_G0290629	DDB_G0290629	NA
chr5	4398765	4399614	-	DDB_G0290631	DDB_G0290631	putative 22 kDa peroxisomal membrane protein that may be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane
chr5	4403175	4404998	+	DDB_G0290633	DDB_G0290633	NA
chr5	4405679	4409722	+	DDB_G0290635	DDB_G0290635	NA
chr5	4410371	4413091	-	DDB_G0290485	dlrA	Leucine-rich repeat molecule required for PKA expression
chr5	4419333	4419989	-	DDB_G0290689	DDB_G0290689	homolog of E. coli rppH%3B very similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0286883%22%3E%3Ci%3EDDB_G0286883%3C%2Fi%3E%3C%2Fa%3E
chr5	4421497	4423147	-	DDB_G0290691	DDB_G0290691	NA
chr5	4424632	4426532	+	DDB_G0290693	eif2b3	EIF2B3 ortholog%2C the eukaryotic initiation factor 2B gamma subunit%3B guanyl nucleotide exchange factor for eIF2%3B defects are linked to leukoencephalopathy with vanishing white matter
chr5	4426907	4429500	-	DDB_G0290687	mhkC	myosin heavy chain kinase%2C an atypical protein serine%2Fthreonine kinase in the Alpha kinase group%3B drives the disassembly of myosin II filaments for efficient cytokinesis%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMhkC%22%3Ecommunity annotation%3C%2Fa%3E
chr5	4431661	4432254	+	DDB_G0290697	DDB_G0290697	NA
chr5	4432334	4433549	-	DDB_G0290695	DDB_G0290695	NA
chr5	4435379	4437847	+	DDB_G0290715	DDB_G0290715	similar to D. purpureum protein
chr5	4438040	4448016	-	DDB_G0290699	pks29	putative type I iterative polyketide synthase 
chr5	4448854	4458868	-	DDB_G0290701	pks30	putative type I iterative polyketide synthase
chr5	4460222	4468561	-	DDB_G0290703	pks31	putative type I iterative polyketide synthase
chr5	4469976	4471730	+	DDB_G0290707	cyp514A4	NA
chr5	4472163	4482268	-	DDB_G0290709	pks32	putative type I iterative polyketide synthase
chr5	4483031	4485569	-	DDB_G0290711	DDB_G0290711_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr5	4485678	4486637	+	DDB_G0290713	DDB_G0290713_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr5	4487859	4489174	+	DDB_G0290719	omt10	NA
chr5	4489219	4490816	-	DDB_G0290721	DDB_G0290721	similar to bacterial aminotransferase class-III proteins%2C which are pyridoxal-phosphate-dependent enzymes
chr5	4494408	4497035	+	DDB_G0290745	pabpc1B	similar to mammalian PABPC1%3B involved in cytoplasmic regulatory processes of mRNA metabolism%2C binding the poly(A) tail of mRNA%3B contains an additional N-terminal H-rich domain
chr5	4499748	4501978	+	DDB_G0290723	mkcB	similar to %3Ci%3EDictyostelium mkcA%3C%2Fi%3E and other mitogen-activated protein kinases (Ste20%2FPAK family)%3B REMI mutant forms aberrant fruiting bodies%2C see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FmkcB%22%3Ecommunity annotation%3C%2Fa%3E
chr5	4502665	4502910	-	DDB_G0290725	lyrm4	belongs to a family of short proteins that includes proteins from the NADH-ubiquinone oxidoreductase complex I%3B named LYR after a highly conserved tripeptide motif
chr5	4504173	4506552	+	DDB_G0290727	DDB_G0290727	NA
chr5	4507516	4517670	+	DDB_G0290729	pks33	putative type I iterative polyketide synthase
chr5	4517745	4522346	+	DDB_G0290747	DDB_G0290747_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr5	4522863	4532622	-	DDB_G0290737	pks34	putative type I iterative polyketide synthase
chr5	4533356	4533736	+	DDB_G0290739	DDB_G0290739_ps	putative pseudogene%3B fragment%2C very similar to several other genes%2C e.g. %3Ca href%3D%22%2Fgene%2FDDB_G0271418%22%3EDDB_G0271418%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0271406%22%3EDDB_G0271406%3C%2Fa%3E
chr5	4534228	4536338	-	DDB_G0290743	cyp514A1	NA
chr5	4537600	4538773	-	DDB_G0290749	DDB_G0290749_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr5	4539649	4547267	+	DDB_G0295667	pks35	putative type I iterative polyketide synthase
chr5	4550115	4558976	+	DDB_G0295659	pks36	putative type I iterative polyketide synthase
chr5	4559095	4561055	-	DDB_G0295661	DDB_G0295661	there is an identical copy of this gene on chromosome 2%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0271532%22%3EDDB_G0271532%3C%2Fa%3E
chr5	4561968	4562531	+	DDB_G0295665	DDB_G0295665	NA
chr5	4563065	4565731	+	DDB_G0290763	DDB_G0290763	NA
chr5	4566125	4566880	+	DDB_G0290753	DDB_G0290753	contains a C2 calcium%2Flipid-binding region (CaLB)
chr5	4567289	4567914	+	DDB_G0290755	DDB_G0290755	contains a C2 calcium%2Flipid-binding region (CaLB)
chr5	4567986	4568692	-	DDB_G0290757	dynF	ortholog of dynactin 6
chr5	4569158	4571140	+	DDB_G0290759	eif2b4	ortholog of human EIF2B4%3B delta subunit of the translation initiation factor eIF2B%2C the guanine-nucleotide exchange factor for eIF2
chr5	4571270	4572330	-	DDB_G0295693	DDB_G0295693	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0285143%22%3E%3Ci%3EDDB_G0285143%3C%2Fi%3E%3C%2Fa%3E
chr5	4572699	4574755	-	DDB_G0290761	sid1	ortholog of C. elegans sid1%2C that enables passive cellular uptake of dsRNA%3B contains 10 transmembrane domains
chr5	4576700	4577548	+	DDB_G0290765	jcdA	NA
chr5	4577727	4578383	-	DDB_G0294603	DDB_G0294603	NA
chr5	4578736	4584404	-	DDB_G0290771	DDB_G0290771	NA
chr5	4584906	4585534	-	DDB_G0290773	DDB_G0290773	NA
chr5	4586394	4587400	+	DDB_G0290767	DDB_G0290767	contains no functional domains and is not similar to any other protein
chr5	4587507	4590601	-	DDB_G0290777	DDB_G0290777	NA
chr5	4590906	4592292	-	DDB_G0290839	DDB_G0290839	NA
chr5	4593057	4593800	-	DDB_G0290781	med20	ortholog of the mediator of RNA polymerase II transcription subunit 20%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr5	4595466	4596123	+	DDB_G0290783	rabG2	NA
chr5	4596636	4598288	-	DDB_G0290785	DDB_G0290785	NA
chr5	4599542	4603525	+	DDB_G0290787	mybO	%3Cb%3ECommunity annotation:%3C%2Fb%3E Myb0 appears to be related to both DUO3 of plants and Gon-4 of animals. DUO3 regulates cell cycle progression in developing pollen and appear to be specifically necessary for mitosis%2C as mutant cells accumulate in G2%2C or become polyploid. DUO3 is expressed in somatic plant tissues mainly in meristerms%2C suggesting a role in cell proliferation%2C though it is apparently has no unique function in this case. In gon-4 (gonadless) mutants of C elegans%2C the gonadal precursors Z1 and Z4 fail to divide. The reason is not known. DUO3%2C Gon-4 share and MybO share two short sequence motifs%2C called the Gc1 and Gc2 regions. Myb0 has an additional simlarity to DUO3 in the region between 876 and 1031%2C which is similar to the DUO3-conserved region 2. This is not present in Gon-4 proteins. Myb0 contains an extended myb-like domain at its C-terminus. In this respect%2C MybO resembles Gon-4. Duo3 does not have a myb domain of any kind%3B however%2C it interacts with DUO1%2C which has an R2R3 class myb domain%2C a domain common to plants. The myb-like domain of mybO is more similar to plant- than to animal myb domains%2C though Dicty also has animal-like mybs (such as mybA). %3Ci%3EHarry MacWilliams%2C March 2011%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FmybO%22%3E There is more information on the wiki page%3C%2Fa%3E
chr5	4603659	4604586	-	DDB_G0290827	DDB_G0290827	NA
chr5	4605000	4605789	-	DDB_G0290829	rabM	NA
chr5	4606115	4606894	-	DDB_G0290779	rabL	NA
chr5	4607175	4607823	-	DDB_G0290831	rabK3	NA
chr5	4608094	4608856	-	DDB_G0290789	rabN1	NA
chr5	4609179	4610053	-	DDB_G0290833	rabK1	NA
chr5	4610784	4611606	-	DDB_G0294571	DDB_G0294571	NA
chr5	4611869	4612312	-	DDB_G0290791	rabK2	NA
chr5	4612672	4613226	-	DDB_G0290793	rabN2	NA
chr5	4613721	4614293	-	DDB_G0290795	hddc2	conserved protein%3B HD domains occur in a superfamily of enzymes with a predicted or known phosphohydrolase activity
chr5	4615081	4615583	+	DDB_G0290797	DDB_G0290797	NA
chr5	4616309	4617578	+	DDB_G0290799	DDB_G0290799	conserved protein %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E  DDB_G0290799 is highly conserved throughout the eukaryotes.  It contains a YjeF domain%2C which in other systems has been implicated in the regulation of RNA stability%2C specifically of genes involved in eukaryotic cell cycle regulation [see Anantharaman and Aravind%2C BMC Genomics 5:45 (2004)].   A budding yeast homolog%2C YKL151C%2C is expressed at M%2FG1 after temperature-sensitive cdc28 synchronization (see %3Ca target %3D%22new%22 href%3D%22http:%2F%2Fgenome-www.stanford.edu%2Fcgi-bin%2Fcellcycle%2FdrawCCquery.pl%22%3EYeast cell cycle analysis project%3C%2Fa%3E).    DDB_G0290799 is 8-fold overexpressed in a Dicty strain lacking the retinoblastoma-like gene rblA%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2FdictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D1472%22%3ErblA-%3C%2Fa%3E (Doquang et al%2C in preparation).  Most genes whose products are necessary for DNA replication%2C centrosome duplication and mitosis are overexpressed by similar factors in this strain.  This supports the idea that DDB_G0290799 is involved in Dicty cell cycle progression.  %3Cbr%2F%3E %3Ci%3EHarry MacWilliams%2C May 2009 %3C%2Fi%3E
chr5	4618085	4619045	+	DDB_G0290801	DDB_G0290801	NA
chr5	4619234	4620337	-	DDB_G0290803	DDB_G0290803	NA
chr5	4620639	4624076	-	DDB_G0290835	DDB_G0290835	NA
chr5	4624322	4625596	-	DDB_G0290805	DDB_G0290805	NA
chr5	4626001	4626869	-	DDB_G0290807	DDB_G0290807_ps	putative pseudogenes%3B fragment%2C similar to a family of %3Ci%3ED. discoideum%3C%2Fi%3E genes including %3Ca href%3D%22%2Fgene%2FDDB_G0290805%22%3E DDB_G0290805%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290821%22%3E DDB_G0290821%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290823%22%3E DDB_G0290823%3C%2Fa%3E
chr5	4626993	4627514	-	DDB_G0290811	DDB_G0290811	NA
chr5	4628184	4636495	-	DDB_G0290815	DDB_G0290815	NA
chr5	4637184	4639849	+	DDB_G0290837	DDB_G0290837	NA
chr5	4642551	4644192	+	DDB_G0290817	DDB_G0290817_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0289849%22%3EDDB_G0289849%3C%2Fa%3E  and %3Ca href%3D%22%2Fgene%2FDDB_G0289817%22%3EDDB_G0289817%3C%2Fa%3E
chr5	4644346	4644471	+	DDB_G0290819	DDB_G0290819	NA
chr5	4644529	4645722	-	DDB_G0290821	DDB_G0290821	NA
chr5	4646192	4647415	-	DDB_G0290823	DDB_G0290823	NA
chr5	4647665	4649476	-	DDB_G0290825	chlA	catalyzes the chlorination step in DIF-1 biosynthesis%3B belongs to the FAD-dependent oxidoreductase family%3B belongs to the tryptophan halogenase family
chr5	4652248	4661413	+	DDB_G0290853	stlB	belongs to the beta-ketoacyl synthase family%3B type III polyketide synthase%3B responsible for phlorocaprophenone (PCP) production%2C the first step in DIF-1 biosynthesis%3B required for the formation of the outer basal disc and the lower cup
chr5	4662421	4667213	+	DDB_G0290841	DDB_G0290841	NA
chr5	4667305	4667565	-	DDB_G0290843	DDB_G0290843	NA
chr5	4668574	4669371	-	DDB_G0290845	gcvH2	lipoylprotein that is reduced as it shuttles the methylamine group of glycine from the P-protein to the T-protein
chr5	4670841	4671197	+	DDB_G0290855	DDB_G0290855	NA
chr5	4672145	4673101	+	DDB_G0290847	DDB_G0290847	NA
chr5	4673270	4674949	-	DDB_G0290849	zmpste24	proteolytically removes the C-terminal three residues of farnesylated proteins%3B contains 6 putative transmembrane domains and an additional signal peptide
chr5	4675467	4676355	+	DDB_G0290851	spc3	ortholog of the conserved microsomal signal peptidase 23 kDa subunit%3B the signal peptidase complex is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum%3B contains a putative signal peptide
chr5	4676692	4682458	+	DDB_G0290893	DDB_G0290893	NA
chr5	4682925	4684848	+	DDB_G0290857	DDB_G0290857	NA
chr5	4688665	4690023	+	DDB_G0290859	DDB_G0290859	member of the AGC kinase group%3B similar to NDR (nuclear Dbf2-related) and RSK (ribosomal S6 kinase) family members
chr5	4690806	4694603	+	DDB_G0290895	DDB_G0290895_ps	putative pseudogene%3B similar to the family of FNIP repeat-containing genes%2C such as  %3Ca href%3D%22%2Fgene%2FDDB_G0289819%22%3EDDB_G0289819%3C%2Fa%3E
chr5	4694739	4695758	-	DDB_G0290863	DDB_G0290863	NA
chr5	4696122	4696786	-	DDB_G0290865	DDB_G0290865_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0282857%22%3EDDB_G0282857%3C%2Fa%3E
chr5	4697072	4698587	-	DDB_G0290869	jcdF	NA
chr5	4698932	4699328	+	DDB_G0290871	DDB_G0290871	NA
chr5	4700102	4702973	+	DDB_G0290873	gacJJ	NA
chr5	4703255	4704162	+	DDB_G0290875	rabP	NA
chr5	4704549	4707141	-	DDB_G0290877	DDB_G0290877	NA
chr5	4708116	4708770	+	DDB_G0290879	DDB_G0290879	NA
chr5	4709313	4709804	+	DDB_G0290881	DDB_G0290881	NA
chr5	4710716	4712193	+	DDB_G0290883	DDB_G0290883	highly similar (93%25 identity) to zfaA (DG17)
chr5	4712501	4713902	+	DDB_G0290897	DDB_G0290897_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0282857%22%3EDDB_G0282857%3C%2Fa%3E
chr5	4714181	4715143	-	DDB_G0290885	DDB_G0290885	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%2C contains a putative signal sequence%3B underexpressed in %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D709%22%3EgskA-%3C%2Fa%3E and %3Ca href%3D%22dictyBase%2Fphenotype%2Fstrain_and_phenotype_details.pl?genotype_id%3D2658%22%3EzakA-%3C%2Fa%3E null mutants
chr5	4716370	4717497	-	DDB_G0290887	DDB_G0290887	conserved %3Ci%3EDictyostelium%3C%2Fi%3E protein%2C contains a putative signal sequence
chr5	4718494	4720165	+	DDB_G0347550	DDB_G0347550	NA
chr5	4720437	4722491	+	DDB_G0347551	DDB_G0347551	NA
chr5	4722780	4725630	-	DDB_G0290891	gacL	NA
chr5	4729019	4733692	+	DDB_G0290901	gefK	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form 
chr5	4734513	4734847	+	DDB_G0290945	DDB_G0290945	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon   
chr5	4735255	4735562	-	DDB_G0290903	DDB_G0290903	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon  
chr5	4735853	4736178	+	DDB_G0290905	DDB_G0290905	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon   
chr5	4736810	4737074	-	DDB_G0290907	DDB_G0290907	NA
chr5	4737794	4739261	+	DDB_G0290909	rpa49	component of the RNA polymerase I complex%3B weakly similar to S. cerevisiae RPA49 and M. musculus RNA polymerase I associated factor 53
chr5	4739761	4739993	-	DDB_G0290911	DDB_G0290911	NA
chr5	4740703	4741678	+	DDB_G0290913	mcfS	similar to slc25a20%2C involved in transport of carnitine%2Facylcarnitine across the mitochondrial membrane %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr5	4742302	4743720	+	DDB_G0290915	DDB_G0290915	NA
chr5	4745027	4748606	-	DDB_G0290919	smc5	functions in chromosome dynamics%3B heterodimerizes with smc6
chr5	4749424	4754406	-	DDB_G0290947	DDB_G0290947	NA
chr5	4755734	4756520	-	DDB_G0290921	bloc1s6	ortholog of human BLOC1S6%2C a component of the BLOC-1 complex%3B mutations in human BLOC1S6 have been linked to Hermansky-Pudlak syndrome 9 
chr5	4757036	4761136	+	DDB_G0290923	DDB_G0290923	NA
chr5	4761330	4763646	-	DDB_G0290925	psiD	similar to dicA1%3B contains a signal peptide%3B expressed in prespore cells
chr5	4764545	4765952	+	DDB_G0290927	etfa	electron transfer flavoprotein (ETF) serves as a specific electron acceptor for several dehydrogenases%3B transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0278849%22%3E%3Ci%3Eetfdh%3C%2Fi%3E%3C%2Fa%3E)%3B defects in human ETFA the cause glutaric aciduria type IIA (GAIIA)
chr5	4767056	4768033	+	DDB_G0290929	gtf2b	general transcription factor required for the initiation of transcription by RNA polymerase II
chr5	4768327	4769935	-	DDB_G0290931	DDB_G0290931	NA
chr5	4770388	4770905	-	DDB_G0290933	DDB_G0290933_ps	putative pseudogene%3B fragment%2C similar to TRAF-type zinc finger-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290931%22%3EDDB_G0290931%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290965%22%3EDDB_G0290965%3C%2Fa%3E
chr5	4771025	4772318	-	DDB_G0290935	zfaA_ps	putative pseudogene%3B similar to a family of D. discoideum zinc finger containing genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0290961%22%3E%3Ci%3EzfaA%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290965%22%3EDDB_G0290965%3C%2Fa%3E
chr5	4772842	4782775	-	DDB_G0290937	pks38	putative type I iterative polyketide synthase
chr5	4785018	4785759	-	DDB_G0290941	DDB_G0290941_ps	putative pseudogene%3B N-terminal fragment of RING zinc finger- and TRAF-type zinc finger-containing proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290931%22%3EDDB_G0290931%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290965%22%3EDDB_G0290965%3C%2Fa%3E
chr5	4786202	4796077	-	DDB_G0290943	pks39	putative type I iterative polyketide synthase 
chr5	4796402	4797686	+	DDB_G0290953	DDB_G0290953_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr5	4798680	4800261	-	DDB_G0290955	DDB_G0290955_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon Tdd-5%3B refer to AF298206 for full-length consensus element
chr5	4802105	4803917	-	DDB_G0290965	DDB_G0290965	NA
chr5	4805100	4805779	-	DDB_G0291041	DDB_G0291041_ps	putative pseudogene%3B fragment%2C similar to a D. discoideum gene family%2C including%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290965%22%3EDDB_G0290965%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0290931%22%3EDDB_G0290931%3C%2Fa%3E
chr5	4806120	4807682	-	DDB_G0290967	DDB_G0290967	NA
chr5	4808227	4809405	-	DDB_G0290969	DDB_G0290969	NA
chr5	4810278	4811798	-	DDB_G0290961	zfaA	NA
chr5	4812963	4814596	+	DDB_G0290957	cprA	NA
chr5	4814825	4816254	-	DDB_G0290971	DDB_G0290971	NA
chr5	4816558	4822244	-	DDB_G0290973	DDB_G0290973	similar to Polysphondylium pallidum protein%3B contains at least two predicted coiled-coil domains
chr5	4822800	4827065	+	DDB_G0291047	xdh	catalyzes the reactions xanthine %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E urate %2B NADH %2B H%2B and xanthine %2B H%3Csub%3E2%3C%2Fsub%3EO %2B O%3Csub%3E2%3C%2Fsub%3E %3C%3D%3E urate %2B H%3Csub%3E2%3C%2Fsub%3EO%3Csub%3E2%3C%2Fsub%3E
chr5	4827309	4827853	-	DDB_G0291049	ost2	subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of S. cerevisiae OST2 and human DAD1 (Defender Against cell Death 1)%3B contains three transmembrane domains
chr5	4829057	4829284	+	DDB_G0291051	DDB_G0291051_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0291151%22%3EDDB_G0291151%3C%2Fa%3E
chr5	4829775	4830788	+	DDB_G0290975	DDB_G0290975	highly similar to cinB (99%25 identity)
chr5	4830916	4831696	-	DDB_G0291053	DDB_G0291053_ps	putative pseudogene%3B similar gene the %3Ca href%3D%22%2Fgene%2FDDB_G0287611%22%3EDDB_G0287611%3C%2Fa%3E and the cAMP phosphodiesterase inhibitor %3Ca href%3D%22%2Fgene%2FDDB_G0277863%22%3EpdiA%3C%2Fa%3E
chr5	4832043	4832721	-	DDB_G0291035	DDB_G0291035_ps	putative pseudogene%3B similar to genes of the RING zinc finger family%2C such as the %3Ca href%3D%22%2Fgene%2FDDB_G0290965%22%3EDDB_G0290965%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290883%22%3EDDB_G0290883%3C%2Fa%3E genes
chr5	4833259	4835306	+	DDB_G0290959	chtC	similar to heat shock protein Hsp20 domain-containing protein%3B but does not contain a Hsp20 domain
chr5	4835830	4836413	+	DDB_G0291055	DDB_G0291055	homolog of human SFT2D1 (SFT2 domain-containing protein 1)%3B contains 4 putative transmembrane domains
chr5	4836534	4837652	-	DDB_G0291057	DDB_G0291057	NA
chr5	4838044	4838564	-	DDB_G0291037	rpb6	subunit common to RNA polymerases I%2C II%2C and III%3B ortholog of S. cerevisiae RPO26
chr5	4839561	4840851	+	DDB_G0291059	DDB_G0291059	contains two ankyrin repeats and two K homology (KH) domains%3B similar to high density lipoprotein-binding protein (vigilin)
chr5	4841153	4842751	+	DDB_G0290977	DDB_G0290977	NA
chr5	4843316	4844587	+	DDB_G0290981	cyp513A2_ps	putative pseudogene%3B related to the cytochrome P450 family
chr5	4844885	4849083	-	DDB_G0290983	DDB_G0290983	NA
chr5	4850945	4853002	-	DDB_G0291039	kif11	belongs to the CENP-E subfamily
chr5	4854167	4856907	+	DDB_G0290985	DDB_G0290985	NA
chr5	4857087	4859177	-	DDB_G0290987	pus1	ortholog of S. cerevisiae PUS1%2Ca  tRNA:pseudouridine synthase that introduces pseudouridines at positions 26-28%2C 34-36%2C 65%2C and 67 of tRNA%3B nuclear protein that appears to be involved in tRNA export%3B also acts on U2 snRNA
chr5	4859470	4863110	-	DDB_G0290989	DDB_G0290989	NA
chr5	4863621	4865155	-	DDB_G0290991	DDB_G0290991	NA
chr5	4865936	4866638	-	DDB_G0290993	DDB_G0290993	NA
chr5	4867138	4868142	-	DDB_G0290995	DDB_G0290995	NA
chr5	4868366	4868729	+	DDB_G0291061	DDB_G0291061	NA
chr5	4869039	4870820	-	DDB_G0290997	mppA2	the mitochondrial processing peptidase removes the transit peptide from the precursor form of proteins imported from the cytoplasm across the mitochondrial inner membrane%3B consists of an alpha and a beta (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0288777%22%3E%3Ci%3EmppB%3C%2Fi%3E%3C%2Fa%3E) subunit%3B there is another alpha subunit%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0274809%22%3E%3Ci%3EmppA1%3C%2Fi%3E%3C%2Fa%3E
chr5	4872338	4875094	-	DDB_G0290999	DDB_G0290999	NA
chr5	4875486	4875815	-	DDB_G0291001	DDB_G0291001	NA
chr5	4876763	4879551	-	DDB_G0291003	DDB_G0291003	NA
chr5	4879944	4881060	+	DDB_G0291005	DDB_G0291005	NA
chr5	4881627	4884694	+	DDB_G0291007	gxcK	NA
chr5	4884944	4885711	-	DDB_G0291009	arpin	NA
chr5	4886164	4889222	-	DDB_G0291011	DDB_G0291011	NA
chr5	4889905	4891053	+	DDB_G0291013	DDB_G0291013	NA
chr5	4891178	4891667	-	DDB_G0291015	DDB_G0291015	possible homolog of human LSM10%2C a U7 snRNA-associated Sm-like protein
chr5	4893398	4893768	-	DDB_G0291017	DDB_G0291017_ps	putative pseudogene%3B fragment%2C similar to  %3Ca href%3D%22%2Fgene%2FDDB_G0271504%22%3ElvsB%3C%2Fa%3E
chr5	4894200	4895222	-	DDB_G0291019	DDB_G0291019	NA
chr5	4896037	4902924	-	DDB_G0290963	kif1	kinesin family member 1%3B ortholog of C. elegans Unc104 and mammalian KIF1A%2C involved in intracellular transport
chr5	4903913	4905457	-	DDB_G0291021	gacD	NA
chr5	4906011	4908009	-	DDB_G0291023	DDB_G0291023	NA
chr5	4908746	4915295	+	DDB_G0291063	thoc2	ortholog of human THOC2 and yeast RLR1%2C which exist in the THO complex required for transcriptional elongation
chr5	4915458	4917902	+	DDB_G0291025	DDB_G0291025	NA
chr5	4918030	4922694	-	DDB_G0291027	DDB_G0291027	NA
chr5	4923512	4928142	-	DDB_G0291045	DDB_G0291045	NA
chr5	4928744	4930510	-	DDB_G0291029	DDB_G0291029	catalyzes the reaction SO%3Csub%3E4%3C%2Fsub%3E%3Csup%3E2-%3C%2Fsup%3E %2B ATP %3C%3D%3E APS %2B pyrophosphate
chr5	4931620	4932570	-	DDB_G0291031	ccs	copper chaperone that specifically delivers Cu to sod1 copper%2Fzinc superoxide dismutase
chr5	4933146	4935712	-	DDB_G0291033	DDB_G0291033	NA
chr5	4936261	4944594	+	DDB_G0291065	DDB_G0291065	NA
chr5	4945727	4946789	-	DDB_G0291067	DDB_G0291067_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr5	4946964	4947608	-	DDB_G0291069	DDB_G0291069_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-D%3B refer to Genbank AF135841 for partial consensus element
chr5	4947710	4947782	-	DDB_G0295265	tRNA-Lys-CUU-7	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr5	4948671	4950021	-	DDB_G0291071	DDB_G0291071	NA
chr5	4950352	4951314	-	DDB_G0291073	DDB_G0291073	NA
chr5	4952079	4953631	-	DDB_G0291107	DDB_G0291107	NA
chr5	4954952	4955620	-	DDB_G0291083	DDB_G0291083	NA
chr5	4955990	4957842	-	DDB_G0291085	gxcE	NA
chr5	4958200	4958553	+	DDB_G0291087	DDB_G0291087_ps	putative pseudogene%3B very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0268772%22%3EDDB_G0268772%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0275721%22%3EDDB_G0275721%3C%2Fa%3E
chr5	4959991	4968054	+	DDB_G0291079	gbpC	member of the TKL (tyrosine kinase-like) group and ROCO family of protein kinases%3B belongs to the LRRK family of protein kinases%3B contains LRR%2C Roc%2C COR%2C RasGEF%2C protein kinase%2C DEP%2C cyclic nucleotide-binding%2C and GRAM domains%3B involved in cGMP-mediated chemotaxis%3B catalyzes GDP to GTP exchange on its own Roc domain%3B translocates from cytoplasm to cell cortex after cAMP stimulation%3B GRAM domain binds directly to plasma membrane
chr5	4968619	4970068	-	DDB_G0291109	DDB_G0291109	NA
chr5	4970973	4971328	+	DDB_G0291089	DDB_G0291089	NA
chr5	4971500	4972203	-	DDB_G0291091	mapbpip	in mammalian cells%2C involved in late endosome function%3B mutations in the human ortholog causes an immunodeficiency syndrome
chr5	4973539	4974132	+	DDB_G0291077	rdiA	NA
chr5	4974992	4976066	-	DDB_G0291081	pefA	similar to mammalian apoptosis component ALG-2%3B contains 5 EF-hand calcium binding domains
chr5	4977011	4980576	-	DDB_G0291111	DDB_G0291111	NA
chr5	4980832	4986471	-	DDB_G0291093	pikH	putative PI3k putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring%3B unlike other PI3Ks%2C does not contain a ras binding domain but a PH domain and does not localize to the cell cortex upon chemotactic stimulation
chr5	4986774	4991939	+	DDB_G0291095	grlP	metabotropic glutamate receptors are coupled to G-proteins and stimulate the inositol phosphate%2FCa2%2B intracellular signaling pathway%3B distinctive %277TM%27 signature
chr5	4992025	4994079	-	DDB_G0291097	vps33	NA
chr5	4994396	4995646	-	DDB_G0291113	aplM	contains three saposin B domains
chr5	4996259	4998085	+	DDB_G0291099	DDB_G0291099	NA
chr5	4998499	4999014	+	DDB_G0291101	DDB_G0291101	NA
chr5	4999483	4999917	+	DDB_G0291103	DDB_G0291103	NA
chr5	5000155	5006931	-	DDB_G0291115	DDB_G0291115	NA
chr5	5007182	5008744	-	DDB_G0291105	cyp513C1	NA
chr5	5009348	5011854	-	DDB_G0291075	warA	controls cell-type proportioning
chr5	5015686	5017081	+	DDB_G0291119	DDB_G0291119	NA
chr5	5017189	5020840	-	DDB_G0291117	noxC	homolog of the mammalian flavocytochrome b large subunit gp91phox%2C essential for spore formation%3B contains calcium-binding EF hand
chr5	5022395	5025752	-	DDB_G0291125	gnrA	NA
chr5	5026489	5027021	+	DDB_G0291129	ndufa6	accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)%2C that is believed to be not involved in catalysis
chr5	5027479	5029714	+	DDB_G0291131	DDB_G0291131	NA
chr5	5030354	5032784	+	DDB_G0291133	DDB_G0291133	putative protein tyrosine kinase%3B similar to S. pombe wee1%2C inhibitor of mitosis through phosphorylation of cdc2
chr5	5033227	5034411	+	DDB_G0291135	DDB_G0291135	NA
chr5	5034573	5036432	-	DDB_G0291185	H3v1	NA
chr5	5037394	5039386	-	DDB_G0291187	DDB_G0291187	similar to A. thaliana PCS1 (phytochelatin synthase 1)%3B catalyzes the reaction glutathione %2B (Glu(-Cys))(n)-Gly %3D Gly %2B (Glu(-Cys))(n%2B1)-Gly
chr5	5040435	5041278	+	DDB_G0291137	DDB_G0291137	NA
chr5	5041464	5042541	-	DDB_G0291139	DDB_G0291139	NA
chr5	5043001	5045875	+	DDB_G0291141	DDB_G0291141	belongs to a family of zinc transporters that are integral membrane proteins%2C which are found to increase tolerance to divalent metal ions%3B contains 15 putative transmembrane domains
chr5	5045979	5046891	-	DDB_G0291143	DDB_G0291143	NA
chr5	5047547	5048311	+	DDB_G0291145	msrB	catalyzes the reaction L-methionine %2B oxidized thioredoxin %3D L-methionine R-oxide %2B reduced thioredoxin
chr5	5049086	5051982	+	DDB_G0291147	DDB_G0291147	NA
chr5	5052148	5053904	-	DDB_G0291149	DDB_G0291149	ortholog of mammalian NARFL (Nuclear prelamin A Recognition Factor-Like protein)
chr5	5054416	5055549	+	DDB_G0291151	DDB_G0291151	NA
chr5	5056007	5057020	+	DDB_G0291121	cinB	induced by cycloheximide
chr5	5057151	5058016	-	DDB_G0291153	DDB_G0291153_ps	putative pseudogene%3B similar gene the %3Ca href%3D%22%2Fgene%2FDDB_G0287611%22%3EDDB_G0287611%3C%2Fa%3E and the cAMP phosphodiesterase inhibitor %3Ca href%3D%22%2Fgene%2FDDB_G0277863%22%3EpdiA%3C%2Fa%3E
chr5	5058540	5059585	-	DDB_G0291155	DDB_G0291155	NA
chr5	5060161	5061624	-	DDB_G0291157	cln3	ortholog of human Cln3%2C which is responsible for Batten%27s disease%2C a juvenile neurological disorder%3B contains 11 transmembrane domains
chr5	5062119	5062973	+	DDB_G0291159	DDB_G0291159	NA
chr5	5063347	5068700	-	DDB_G0291161	DDB_G0291161	NA
chr5	5070813	5073466	+	DDB_G0291127	mvpB	NA
chr5	5073815	5077009	-	DDB_G0291123	glpD	CAZy family GT35%3B 5%27-AMP-independent glycogen phosphorylase expressed in late development%3B the combined activities of glpV and glpD results in constant glycogen phosphorylase activity throughout development 
chr5	5077769	5082571	-	DDB_G0291163	nup155	component of the nuclear pore complex%2C may be involved both in binding and translocating proteins
chr5	5083069	5083296	+	DDB_G0291165	DDB_G0291165	NA
chr5	5083393	5084190	-	DDB_G0291167	DDB_G0291167	NA
chr5	5084851	5085694	+	DDB_G0291189	DDB_G0291189	NA
chr5	5086072	5087429	-	DDB_G0291191	DDB_G0291191	highly similar to Dictyostelium cprA
chr5	5087724	5088863	-	DDB_G0291193	nubpl	conserved protein%3B belongs to the Mrp%2FNBP35 ATP-binding protein family
chr5	5089340	5090233	+	DDB_G0291169	DDB_G0291169	NA
chr5	5090921	5091802	+	DDB_G0291171	DDB_G0291171	NA
chr5	5092325	5093394	+	DDB_G0291195	DDB_G0291195	similar to S. cereviaiae Nnt1p
chr5	5094013	5096016	+	DDB_G0291197	hbx3	NA
chr5	5096341	5097214	-	DDB_G0291173	ndufv2	ortholog of the mammalian NDUFV2 (NADH dehydrogenase ubiquinone flavoprotein 2) that transfers electrons from NADH to the respiratory chain
chr5	5097563	5100774	+	DDB_G0291175	DDB_G0291175	NA
chr5	5101333	5102110	+	DDB_G0291177	tspE	has similarity to the mammalian CD9 antigen%3B contains a tetraspanin and 4 putative transmembrane domains
chr5	5102281	5103838	-	DDB_G0291179	metK	catalyzes the reaction ATP %2B L-methionine %2B H%3Csub%3E2%3C%2Fsub%3EO %3D phosphate %2B pyrophosphate %2B S-adenosyl-L-methionine
chr5	5105448	5106837	+	DDB_G0291181	DDB_G0291181	NA
chr5	5107365	5110847	-	DDB_G0291183	dhx8	conserved RNA helicase%3B  S. cerevisiae ortholog PRP22 mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
chr5	5112561	5114603	-	DDB_G0291201	ctrC	similar to mammalian SLC7A1-4 (solute carrier family 7%2C members 1 to 4)%3B multi-pass membrane protein%2C contains 15 predicted transmembrane domains
chr5	5116417	5118404	+	DDB_G0291203	DDB_G0291203	similar to D. purpureum protein%3B contains a region conserved with eukaryotic transmembrane receptors  (lung_7-TM_R: PF06814)%3B contains 7 putative transmembrane domains
chr5	5120775	5123753	+	DDB_G0291205	DDB_G0291205	NA
chr5	5123925	5124972	-	DDB_G0291199	ube2t	interacts with the Fanconi anaemia complex involved DNA cross-link repair%3B null mutant is sensitive to DNA damaging agents   %3Cbr%2F%3E%3Cbr%2F%3E  the mammalian Fanconi anaemia nuclear complex includes FANC A%2C B%2C C%2C E%2C F%2C G%2C L and M%3B  the FA complex interacts with ube2t%2C a E2 ubiquitin-conjugating enzyme%2C to monoubiquitinate  FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the  FANCJ helicase as well as FANCN and FANCD1%3B  Dictyostelium has orthologs for %3Ca href%3D%22%2Fgene%2FDDB_G0268216%22%3EFANCD2%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0279669%22%3EFANCE%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0292744%22%3EFANCL%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0293476%22%3EFANCI%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0286621%22%3EFANCJ%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274841%22%3EFANCM%3C%2Fa%3E and   %3Ca href%3D%22%2Fgene%2FDDB_G0291199%22%3EUbe2t%3C%2Fa%3E.
chr6	1271	2278	-	DDB_G0291221	DDB_G0291221_RTE	ORF1 protein of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr6	2814	3661	-	DDB_G0291209	DDB_G0291209_ps	putative pseudogene%3B highly similar to a %3Ci%3ED. discoideum%3C%2Fi%3E gene family including %3Ca href%3D%22%2Fgene%2FDDB_G0274765%22%3E DDB_G0274765%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0267252%22%3E DDB_G0267252%3C%2Fa%3E
chr6	4067	5254	-	DDB_G0291213	DDB_G0291213_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chr6	6464	7366	+	DDB_G0291223	DDB_G0291223_RTE	fused fragments of the DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr6	8948	9660	+	DDB_G0291215	DDB_G0291215_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chr6	10525	10879	+	DDB_G0291219	DDB_G0291219_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chr6	11026	11945	-	DDB_G0291217	DDB_G0291217_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chr6	14558	16151	-	DDB_G0291257	DDB_G0291257_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr6	18892	20873	+	DDB_G0291259	DDB_G0291259	contains a ubiquitin domain and a UBX domain found in ubiquitin-regulatory proteins
chr6	21629	22263	+	DDB_G0291261	DDB_G0291261	protein conserved in bacteria and plants%3B D. discoideum contains a second highly similar protein (%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0286259%22%3EDDB_G0286259 %3C%2Fa%3E)
chr6	22760	27692	+	DDB_G0291263	DDB_G0291263	NA
chr6	28140	28759	+	DDB_G0291265	gloA	catalyzes the reaction glutathione %2B methylglyoxal %3C%3D%3E S-lactoylglutathione
chr6	29253	29973	-	DDB_G0291255	29C	similar to DDB_G0278725%3B contains a predicted signal peptide
chr6	31751	34467	-	DDB_G0291251	limD	NA
chr6	35064	36752	-	DDB_G0291267	dst3	putative protein serine%2Fthreonine kinase%3B the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B stress-responsive kinase
chr6	37774	38385	+	DDB_G0291269	spg1	similar to S. pombe Sid3
chr6	38541	39827	-	DDB_G0291271	eif2b2	guanyl nucleotide exchange factor for eIF2
chr6	40029	40659	+	DDB_G0291273	dtd	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr) in yeast%3B substrate specifity may be broader
chr6	41617	44215	+	DDB_G0291275	mcln	ortholog of mucolipin%2C when defective causing mucolipidosis type IV%3B putative Ca2%2B channel%3B contains a potential Ca2%2B-binding EF hand as a regulatory site and 6 putative transmembrane domains
chr6	44334	44966	-	DDB_G0291277	DDB_G0291277	NA
chr6	45543	47117	+	DDB_G0291279	DDB_G0291279	contains 11 putative transmembrane domains%3B similar to feline leukemia virus subgroup C receptor-related proteins
chr6	48286	48858	+	DDB_G0291281	DDB_G0291281	NA
chr6	49486	50829	-	DDB_G0291241	gnt2	NA
chr6	51803	53476	+	DDB_G0291283	sptB	similar to S. cerevisiae LCB2%3B dimerizes with SptA to catalyze the conversion of palmitoyl-CoA %2B L-serine into CoA %2B 3-dehydro-D-sphinganine %2B CO%3Csub%3E2%3C%2Fsub%3E
chr6	53775	56128	+	DDB_G0291285	DDB_G0291285	NA
chr6	57345	59218	+	DDB_G0291287	tmem184D	TMEM184 family protein%3B contains 7 predicted transmembrane domains
chr6	59612	63790	+	DDB_G0291289	DDB_G0291289	NA
chr6	65139	68579	+	DDB_G0291231	mhkA	myosin II heavy chain kinase is an atypical protein serine%2Fthreonine kinase in the Alpha kinase group%3B phosphorylates the myosin II heavy chain and drives myosin II disassembly
chr6	69233	69619	+	DDB_G0291291	ecmF	similar to staA and other short proteins expressed in the prestalk region%3B expressed in pstA cells
chr6	69908	70492	+	DDB_G0291293	rabU	NA
chr6	70728	72507	-	DDB_G0291648	lpd	common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate%2C 2-oxoglutarate%2C and the branched-chain 2-oxo acids and of the glycine cleavage system complex
chr6	72961	78028	+	DDB_G0291297	med14	ortholog of the mediator of RNA polymerase II transcription subunit 14%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr6	78789	80092	+	DDB_G0291235	ranA	NA
chr6	80308	81714	-	DDB_G0291299	DDB_G0291299	NA
chr6	82693	86689	+	DDB_G0291650	DDB_G0291650	conserved protein that serves as receptor for nuclear localization signals (NLS) in cargo substrates and functions as nuclear transport receptor
chr6	87606	91138	+	DDB_G0291301	DDB_G0291301	at the N-terminus similar to peroxisomal sarcosine oxidases (PSO)%2C at the C-terminus similar to L-amino-acid oxidases (LAO)
chr6	91358	93578	-	DDB_G0291652	shmt2	mitochondrial serine hydroxymethyltransferase%3B catalyzes the reaction L-serine %2B tetrahydrofolate %3C%3D%3E L-glycine %2B 5%2C10-methylene-tetrahydrofolate %2B H%3Csub%3E2%3C%2Fsub%3EO
chr6	93960	97507	-	DDB_G0291303	frmA	involved in substrate adhesion by regulating the turnover of paxillin%2Ftalin adhesion sites%3B also involved in cell-cell adhesion and affecting tip formation during development.
chr6	98914	99707	+	DDB_G0291237	rapA	rap related protein
chr6	100153	102198	+	DDB_G0294555	DDB_G0294555	NA
chr6	102439	105968	-	DDB_G0291306	xpo1	ortholog of H. sapiens XPO1 and S. cerevisiae CRM1 involved in export from the nucleus
chr6	107010	112507	-	DDB_G0291308	DDB_G0291308	NA
chr6	112763	113905	+	DDB_G0291310	DDB_G0291310	NA
chr6	114038	115324	-	DDB_G0291312	mcfA	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3B contains at least three transmembrane domains%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr6	116087	118838	+	DDB_G0291314	DDB_G0291314	highly similar to plant HSP101%3B similar to endopeptidase Clp%3B expressed in prespore cells
chr6	118975	120149	-	DDB_G0291316	DDB_G0291316	NA
chr6	120345	120716	+	DDB_G0291318	DDB_G0291318	has similarity to yeast mrp10%2C the mitochondrial ribosome 37 S subunit component
chr6	120925	123655	-	DDB_G0291320	pop1	protein subunit of both the RNase P complex involved in tRNA processing and the RNase MRP complex involved in rRNA processing
chr6	123984	126614	+	DDB_G0291322	DDB_G0291322	NA
chr6	126721	127419	-	DDB_G0291324	DDB_G0291324	NA
chr6	127766	127996	-	DDB_G0291326	DDB_G0291326	NA
chr6	128308	129151	-	DDB_G0291328	DDB_G0291328	NA
chr6	130125	131591	+	DDB_G0291330	kctd9	highly similar to vertebrate potassium channel tetramerization domain-containing proteins%3B contains four pentapeptide repeats and a doublecourtin domain%3B enriched in gametes
chr6	131894	133039	-	DDB_G0291332	DDB_G0291332	NA
chr6	133565	134140	+	DDB_G0291334	DDB_G0291334	NA
chr6	134282	135368	-	DDB_G0291336	DDB_G0291336	NA
chr6	135540	136271	+	DDB_G0291338	DDB_G0291338	NA
chr6	136448	137910	-	DDB_G0291340	DDB_G0291340	NA
chr6	138933	139991	-	DDB_G0291654	DDB_G0291654	NA
chr6	140829	143261	+	DDB_G0291342	tacA	transcription factor regulated by calcineurin to localize from the cytosol to the nucleus%2C where it might be phosphorylated by GskA%3B involved in stalk cell differentiation and the stress response to lithium
chr6	143653	145741	+	DDB_G0291344	DDB_G0291344	similar to butyrylcholinesterase and acetylcholinesterase precursor proteins%3B contains a putative signal peptide
chr6	145941	153138	-	DDB_G0291229	abpF	actin-binding protein that localizes to the centrosome%3B expression enhanced in myosin II knock-out cells%3B purified protein makes ring-like structures in vitro (from K. R. Niebling%27s Thesis (1993)%2C James Spudich Lab%2C Standford U.)
chr6	154547	157369	+	DDB_G0291346	mleuS	catalyzes the reaction ATP %2B L-leucine %2B tRNALeu %3D AMP %2B diphosphate %2B L-leucyl-tRNALeu
chr6	160343	162658	+	DDB_G0291348	DDB_G0291348	NA
chr6	162730	164249	-	DDB_G0291350	DDB_G0291350	putative protein serine%2Fthreonine kinase%3B similar to mammalian MPSK (myristoylated and palmitoylated serine%2Fthreonine kinase)%2C a kinase involved in transcriptional regulation and protein phosphorylation%3B may be an intermediary in the TGF-beta signaling pathway
chr6	166985	169109	+	DDB_G0291352	psenA	putative catalytic subunit of the gamma-secretase complex%3B similar to presenilin 2%2C a gene that has been associated with early-onset familial Alzheimer%27s disease
chr6	169469	172368	-	DDB_G0291354	DDB_G0291354	NA
chr6	173621	176169	-	DDB_G0291356	grlE	major GABA receptor during late development%3B GABA-B receptor with distinctive %277TM%27 signature%3B also similar to metabotropic glutamate receptors also binds glutamate in a competitive manner to GABA%3B seems to interact with two different trimeric G-proteins depending on ligand%2C one that stimulates the PI3 kinase pathway and one acting through G%26alpha%3B9%3B involved in sporulation
chr6	177191	179304	-	DDB_G0291358	cct2	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr6	180176	180784	+	DDB_G0291656	ykt6	ortholog of the YKT6 vesicle membrane protein (v-SNARE) involved in protein traffiking
chr6	180987	182201	-	DDB_G0291360	dus4l	ortholog of S. cerevisiae DUS4 and the animal DUS4L%3B catalyzes the synthesis of dihydrouridine%2C a modified base found in the D-loop of tRNAs
chr6	182518	183059	+	DDB_G0291362	rpc19	subunit common to RNA polymerases I and III%3B ortholog of S. cerevisiae RPC19
chr6	183283	183801	+	DDB_G0291364	DDB_G0291364	NA
chr6	184226	184999	-	DDB_G0291366	DDB_G0291366	belongs to the thioredoxin family%3B similar to A. thaliana PRXIIF (peroxiredoxin IIF)%3B lacks redox-active cysteine compared with many homologs%2C so may be catalytically inactive
chr6	185417	186627	+	DDB_G0291368	serB	catalyzes the reaction 3-phospho-serine %2B H%3Csub%3E2%3C%2Fsub%3EO %3C%3D%3E L-serine %2B phosphate
chr6	186929	188300	+	DDB_G0291658	DDB_G0291658	NA
chr6	189530	191957	+	DDB_G0291660	smp3	CAZy family GT76%3B catalyzes the addition of the fourth mannose to GPI (glycosylphosphatidylinositol)
chr6	192185	193390	-	DDB_G0291370	DDB_G0291370	contains catalytic domain only
chr6	197774	199582	+	DDB_G0291372	dimB	required for expression of prestalk genes in response to DIF-1%3B optimal binding to DNA sequences containing CACA
chr6	199740	200765	-	DDB_G0291374	DDB_G0291374	ortholog of the H. sapiens TEX261 (testis expressed 261)%3B contains a putative N-terminal signal sequence and 3 to 4 additional transmembrane domains
chr6	201367	203505	+	DDB_G0291225	cct7	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr6	203637	204279	-	DDB_G0291376	adi1	ortholog of the conserved acireductone dioxygenase involved in the methionine salvage pathway
chr6	205952	213677	+	DDB_G0291378	forJ	contains a SMAD%2FFHA domain%2C an actin-binding FH2 (formin homology 2) domain%2C and a RmlC-like cupin domain
chr6	214264	224083	-	DDB_G0291380	atr1	atypical%2C PIKK family protein kinase%3B similar to protein kinase ATR%2C which modulates cell cycle progression and DNA repair%3B in other organisms%2C ATR phosphorylates Rad17%2C histone H2AX%2C p53 and Nbs1
chr6	224492	224947	-	DDB_G0291382	DDB_G0291382	NA
chr6	226725	228889	+	DDB_G0291384	DDB_G0291384	similar to CorA family transporters found in fungi
chr6	229175	230870	+	DDB_G0291386	DDB_G0291386	NA
chr6	231261	231479	-	DDB_G0291388	DDB_G0291388	NA
chr6	235528	238287	+	DDB_G0291608	DDB_G0291608	NA
chr6	239658	246409	+	DDB_G0291390	nup98	very similar to the mammalian Nup98 precurser that is processed into two peptides%2C Nup96 and Nup98%2C through autoproteolysis
chr6	246726	248655	-	DDB_G0291392	DDB_G0291392	similar to spore coat protein PspB%3B expressed in prespore cells
chr6	249853	251072	+	DDB_G0291394	DDB_G0291394	NA
chr6	252157	255413	+	DDB_G0291396	DDB_G0291396	contains a dilute domain%2C found at the carboxyl terminus of non-muscle myosin V
chr6	255522	257550	-	DDB_G0291400	DDB_G0291400	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane
chr6	257921	258459	-	DDB_G0291402	DDB_G0291402	NA
chr6	259277	260112	+	DDB_G0291404	eif3K	EIF3SK ortholog%2C the eukaryotic initiation factor 3 subunit%3B in human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr6	260638	273157	+	DDB_G0291406	DDB_G0291406	NA
chr6	273229	273810	-	DDB_G0291408	DDB_G0291408	conserved protein in %3Ci%3EDictyostelium%3C%2Fi%3E%2C fungi%2C and bacteria
chr6	274574	275524	+	DDB_G0291410	DDB_G0291410	NA
chr6	275731	278168	-	DDB_G0291412	srp72	component of the signal recognition particle (SRP)%2C which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulum
chr6	278393	278782	+	DDB_G0291414	DDB_G0291414	NA
chr6	279007	279818	-	DDB_G0291416	DDB_G0291416	NA
chr6	280209	281600	+	DDB_G0291418	DDB_G0291418	NA
chr6	281774	282462	-	DDB_G0291662	pop5	protein subunit of both the RNase P complex involved in tRNA processing and the RNase MRP complex involved in rRNA processing
chr6	283328	285935	+	DDB_G0291239	ubpA	putative ortholog of H. sapiens USP5 and S. cerevisiae UBP14
chr6	286253	286468	-	DDB_G0291420	DDB_G0291420	NA
chr6	286642	286965	-	DDB_G0291422	DDB_G0291422	NA
chr6	289088	291921	+	DDB_G0291424	DDB_G0291424	NA
chr6	292100	293080	-	DDB_G0291426	DDB_G0291426	NA
chr6	293845	295089	+	DDB_G0291428	DDB_G0291428	contains a predicted signal peptide%3B similar to Polysphondylium pallidum 64 kDa cell surface glycoprotein
chr6	295544	297610	+	DDB_G0291430	DDB_G0291430	NA
chr6	297698	299362	-	DDB_G0291432	DDB_G0291432	NA
chr6	299936	301894	-	DDB_G0291434	pdi2	catalyzes the rearrangement of disulfide bonds in proteins
chr6	302806	304187	+	DDB_G0291436	DDB_G0291436	NA
chr6	304287	308310	-	DDB_G0291438	nol6	putative U3 snoRNP protein%3B ortholog of H. sapiens NOL6 and S. cerevisiae UTP22
chr6	308878	310365	+	DDB_G0291440	coq6	similar to S. cerevisiae COQ6%2C a putative flavin-dependent monooxygenase%2C involved in ubiquinone (Coenzyme Q) biosynthesis
chr6	310825	310905	-	DDB_G0295471	tRNA-Leu-CAA-4	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	312209	313024	-	DDB_G0291233	rabA	NA
chr6	313947	319147	-	DDB_G0291245	abcA6	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr6	319912	320231	-	DDB_G0291442	DDB_G0291442	NA
chr6	320738	322210	+	DDB_G0291444	DDB_G0291444	NA
chr6	322306	322809	-	DDB_G0291446	DDB_G0291446	NA
chr6	323423	323494	+	DDB_G0295299	tRNA-Glu-UUC-15	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	323966	325932	-	DDB_G0291448	cyp519D1	NA
chr6	326534	329866	-	DDB_G0291450	DDB_G0291450	NA
chr6	330303	332395	-	DDB_G0291452	DDB_G0291452	NA
chr6	333292	336043	-	DDB_G0291454	tgrC4	NA
chr6	338918	341906	+	DDB_G0291664	DDB_G0291664	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0291516%22%3E%3Ci%3EDDB_G0291516%3C%2Fi%3E%3C%2Fa%3E
chr6	342766	343759	+	DDB_G0291458	tgrA_ps7	putative pseudogene%3B fragment of immunoglobulin E-set family genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0291622%22%3E%3Ci%3EtgrA1%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0291666%22%3E%3Ci%3EtgrA2%3C%2Fi%3E%3C%2Fa%3E
chr6	344609	347624	+	DDB_G0291622	tgrA1	contains a putative signal peptide and a C-terminal transmembrane domain%3B in a cluster of recently duplicated genes and almost identical to %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291666%22%3E %3Ci%3EDDB_G0291666%3C%2Fi%3E%3C%2Fa%3E and very similar to  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291668%22%3E%3Ci%3EDDB_G0291668%3C%2Fi%3E%3C%2Fa%3E and  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291514%22%3E%3Ci%3EDDB_G0291514%3C%2Fi%3E%3C%2Fa%3E
chr6	348356	351531	+	DDB_G0291460	tgrA_ps2	putative pseudogene%3B immunoglobulin E-set family gene
chr6	352396	355592	+	DDB_G0291666	tgrA2	in a cluster of recently duplicated genes and almost identical to %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291622%22%3E%3Ci%3EDDB_G0291622%3C%2Fi%3E%3C%2Fa%3E%2C  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291668%22%3E%3Ci%3EDDB_G0291668%3C%2Fi%3E%3C%2Fa%3E%2C and  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291514%22%3E%3Ci%3EDDB_G0291514%3C%2Fi%3E%3C%2Fa%3E
chr6	356398	359105	+	DDB_G0291624	tgrA_ps1	putative pseudogene%3B immunoglobulin E-set family gene
chr6	359944	363863	+	DDB_G0291668	tgrA3	contains a predicted signal peptide and an additional transmembrane domain%3B in a cluster of recently duplicated genes and very similar to  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291622%22%3E%3Ci%3EDDB_G0291622%3C%2Fi%3E%3C%2Fa%3E%2C  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291666%22%3E%3Ci%3EDDB_G0291666%3C%2Fi%3E%3C%2Fa%3E%2C and   %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291514%22%3E%3Ci%3EDDB_G0291514%3C%2Fi%3E%3C%2Fa%3E 
chr6	364638	366239	+	DDB_G0291670	DDB_G0291670	has some similarity to the human splicing coactivator subunit SRm300
chr6	366300	367520	-	DDB_G0291462	DDB_G0291462	NA
chr6	368247	368532	-	DDB_G0291626	DDB_G0291626	NA
chr6	369674	373973	-	DDB_G0291464	DDB_G0291464	NA
chr6	376634	377962	-	DDB_G0291466	DDB_G0291466	NA
chr6	378403	380189	+	DDB_G0291468	DDB_G0291468	NA
chr6	380554	381585	+	DDB_G0291470	DDB_G0291470	NA
chr6	381635	383021	-	DDB_G0291472	DDB_G0291472	NA
chr6	383676	385001	-	DDB_G0291247	mfeA	NA
chr6	387018	387324	+	DDB_G0291628	DDB_G0291628	NA
chr6	387688	391673	+	DDB_G0291474	DDB_G0291474	NA
chr6	391713	395873	-	DDB_G0291243	abcC7	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr6	396540	397265	+	DDB_G0291476	DDB_G0291476	expressed in prespore cells
chr6	397697	403037	+	DDB_G0291606	vps8	putative ortholog of VPS8%2C involved in vacuolar protein localization
chr6	403181	404869	-	DDB_G0291227	ctrA	similar to mammalian SLC7A1-4 (solute carrier family 7%2C members 1 to 4)%3B multi-pass membrane protein%2C contains 15 predicted transmembrane domains
chr6	405733	407246	-	DDB_G0291478	DDB_G0291478	NA
chr6	408084	408418	+	DDB_G0291672	DDB_G0291672	NA
chr6	408654	410532	-	DDB_G0291480	DDB_G0291480	NA
chr6	411372	412250	+	DDB_G0291482	gloB2	catalyzes the reaction S-lactoyl-glutathione %2B H2O %3C%3D%3E reduced glutathione %2B D-lactate
chr6	412297	413241	-	DDB_G0291484	DDB_G0291484	NA
chr6	413873	415521	+	DDB_G0291486	DDB_G0291486	similar to CUGBP proteins and Bruno-like proteins%3B human CUGBP1 regulates splicing and translation of various RNAs%3B contains 3 RRM domains
chr6	417129	418431	-	DDB_G0291488	DDB_G0291488	NA
chr6	418715	420424	-	DDB_G0295475	DDB_G0295475	contains no functional domains
chr6	421140	423349	-	DDB_G0291490	pigT	NA
chr6	423677	425112	-	DDB_G0291492	DDB_G0291492	NA
chr6	426330	427553	+	DDB_G0291610	DDB_G0291610_ps	putative pseudogene%3B similar to a family of genes including %3Ca href%3D%22%2Fgene%2FDDB_G0291428%22%3EDDB_G0291428%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0291572%22%3EDDB_G0291572%3C%2Fa%3E
chr6	427952	429587	+	DDB_G0291632	DDB_G0291632	NA
chr6	430069	430966	+	DDB_G0291494	DDB_G0291494	NA
chr6	431044	432131	-	DDB_G0291674	DDB_G0291674	similar to bacterial short-chain dehydrogenase%2Freductase family proteins%2C and human RDH8 (retinol dehydrogenase 8)
chr6	432569	433581	-	DDB_G0291676	DDB_G0291676	similar to bacterial short-chain dehydrogenase%2Freductase family proteins
chr6	434272	434856	-	DDB_G0291253	dia2	lysine and leucine rich protein specifically expressed during the transition from growth to development%3B located in the ER in vegetative cells and in prespore vesicles during development
chr6	435835	437018	+	DDB_G0291496	DDB_G0291496	NA
chr6	437512	439287	-	DDB_G0291498	cpnF	Ca(2%2B)-dependent phospholipid-binding protein%3B contains two C2 domains and a VWFA domain.
chr6	440410	442359	+	DDB_G0291500	tgrA_ps3	putative pseudogene%3B immunoglobulin E-set family gene
chr6	442657	449964	-	DDB_G0291249	rrpB	one of the three %3Ci%3ED. discoideum%3C%2Fi%3E RNA-directed RNA polymerases%2C for which a distinct function has not yet been identified
chr6	450396	451392	-	DDB_G0291506	gins3	subunit 3 of the conserved replication complex GINS%2C which is essential for initiation of DNA replication in X. laevis
chr6	452441	452590	+	DDB_G0291508	DDB_G0291508	NA
chr6	452902	456759	-	DDB_G0291510	DDB_G0291510	ortholog of the human GTPase activating Rap%2FranGAP protein GARNL3%3B contains a Rap%2Fran-GAP domain and a citron-like domain
chr6	457932	458567	-	DDB_G0291636	rpb5	subunit common to RNA polymerases I%2C II%2C and III%3B ortholog of S. cerevisiae RPB5
chr6	459846	462386	+	DDB_G0291512	epnA	epsin interacts dynamically with clathrin-coated pits at the plamid membrane and plays a role in cytokinesis and spore morphology%3B regulates Hip1r phosphorylation with its ENTH domain
chr6	462725	466355	-	DDB_G0291514	tgrA4	contains a putative signal peptide and one additional transmembrane domain%3B almost identical to %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291622%22%3E%3Ci%3EDDB_G0291622%3C%2Fi%3E%3C%2Fa%3E%2C  %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291666%22%3E%3Ci%3EDDB_G0291666%3C%2Fi%3E%3C%2Fa%3E%2C and     %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0291668%22%3E%3Ci%3EDDB_G0291668%3C%2Fi%3E%3C%2Fa%3E
chr6	469339	472331	+	DDB_G0291516	DDB_G0291516	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0291664%22%3E%3Ci%3EDDB_G0291664%3C%2Fi%3E%3C%2Fa%3E
chr6	473275	473618	+	DDB_G0291518	DDB_G0291518	contains one predicted transmembrane domain
chr6	473965	475269	-	DDB_G0291520	iliO	contains a DRB0094-related RNA ligase domain%2C conserved in bacteria%2C phages%2C and fungi%3B similar to D. purpureum protein%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr6	476401	476999	+	DDB_G0291638	DDB_G0291638	NA
chr6	478316	478961	+	DDB_G0291522	DDB_G0291522	NA
chr6	479074	480560	-	DDB_G0291524	DDB_G0291524	very similar to human NAGA%2C an alpha-N-acetylgalactosaminidase which catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides
chr6	481211	482065	-	DDB_G0291526	rps14	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S14 homolog
chr6	482754	484435	+	DDB_G0291528	iptB	IPP transferases modify both cytoplasmic and mitochondrial tRNAs at A(37) to give isopentenyl A(37)
chr6	485007	486173	+	DDB_G0291530	DDB_G0291530	NA
chr6	486511	487507	+	DDB_G0291532	DDB_G0291532	NA
chr6	487852	489052	+	DDB_G0291534	DDB_G0291534	NA
chr6	490155	495242	-	DDB_G0291536	gnrB	gelsolin domain-containing protein
chr6	496074	496376	-	DDB_G0291640	DDB_G0291640	NA
chr6	497249	498924	+	DDB_G0291612	DDB_G0291612	NA
chr6	499055	500540	-	DDB_G0291562	osbL	NA
chr6	501788	503084	+	DDB_G0291560	DDB_G0291560_ps	putative pseudogene
chr6	503745	504164	-	DDB_G0291558	DDB_G0291558	NA
chr6	504463	505870	-	DDB_G0291556	prmt1	ortholog of H. sapiens PRMT1 and S. cerevisiae HMT1 involved in methylation of hnRNPs
chr6	506713	509046	+	DDB_G0291554	DDB_G0291554	NA
chr6	509192	510853	+	DDB_G0291678	DDB_G0291678_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0291546%22%3EDDB_G0291546%3C%2Fa%3E
chr6	511252	512197	-	DDB_G0291552	DDB_G0291552_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291540%22%3EDDB_G0291540%3C%2Fa%3E
chr6	512943	514805	+	DDB_G0291548	DDB_G0291548	NA
chr6	515184	518081	+	DDB_G0291546	DDB_G0291546	NA
chr6	518857	523393	+	DDB_G0291544	DDB_G0291544	NA
chr6	523707	524111	-	DDB_G0291542	DDB_G0291542_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291540%22%3EDDB_G0291540%3C%2Fa%3E
chr6	524418	526344	-	DDB_G0291642	DDB_G0291642_ps	putative pseudogene%3B similar to a D. discoideum gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0291540%22%3EDDB_G0291540%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0291644%22%3EDDB_G0291644%3C%2Fa%3E
chr6	526360	527919	-	DDB_G0291644	DDB_G0291644	NA
chr6	528420	529465	+	DDB_G0291680	DDB_G0291680_ps	putative pseudogene%3B very similar to  %3Ca href%3D%22%2Fgene%2FDDB_G0291616%22%3EDDB_G0291616%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0291580%22%3EDDB_G0291580%3C%2Fa%3E
chr6	530842	532518	-	DDB_G0291540	DDB_G0291540	NA
chr6	533329	533874	+	DDB_G0291538	DDB_G0291538	similar to bacterial acetyltransferases%3B homolog of E. coli maa (maltose O-acetyltransferase)%3B contains a predicted peroxisomal targeting signal
chr6	533918	535519	-	DDB_G0291682	DDB_G0291682_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0291540%22%3EDDB_G0291540%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0291644%22%3EDDB_G0291644%3C%2Fa%3E
chr6	536394	544131	-	DDB_G0291614	pks40	putative type I iterative polyketide synthase
chr6	545874	553580	-	DDB_G0291684	pks41	putative type I iterative polyketide synthase
chr6	555673	556042	+	DDB_G0291564	DDB_G0291564	NA
chr6	556339	557876	-	DDB_G0291566	grwd1	ortholog of the mammalian GRWD1%3B contains several WD-40 repeats
chr6	558877	560367	+	DDB_G0291568	dnaja1	conserved molecular chaperone%2C DnaJ homolog subfamily A member 1
chr6	561048	564580	+	DDB_G0291570	exo1	highly similar to S. pombe exonuclease I%2C a 5%27-%3E3%27 exonuclease involved in DNA repair%2C recombination%2C replication and telomere integrity%3B in Dictyostelium%2C involved in double strand repair via homologous recombination (HR)
chr6	564716	565964	-	DDB_G0291572	DDB_G0291572	NA
chr6	566754	567563	-	DDB_G0291574	DDB_G0291574	contains a signal peptide and two transmembrane domains
chr6	569331	570269	+	DDB_G0291576	DDB_G0291576	conserved hypothetical protein%3B contains a putative N-terminal signal sequence
chr6	571007	571492	+	DDB_G0291578	DDB_G0291578	member of a small Dictyostelium gene family%3B missing the carboxyl half compared to related proteins
chr6	571564	572610	+	DDB_G0291580	DDB_G0291580	member of a small Dictyostelium gene family
chr6	573502	574514	+	DDB_G0291582	DDB_G0291582_ps	NA
chr6	575206	576255	+	DDB_G0291616	DDB_G0291616	member of a small Dictyostelium gene family
chr6	576491	577523	+	DDB_G0291586	DDB_G0291586_ps	putative pseudogene%3B very similar to a small D. discoideum gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0291580%22%3EDDB_G0291580%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0291616%22%3EDDB_G0291616%3C%2Fa%3E
chr6	577637	579628	-	DDB_G0291588	ddx55	ortholog of H. sapiens DDX55 and S. cerevisiae SBP4 (Suppressor of PAB1)%3B SBP4 required for synthesis of 60S ribosomal subunits
chr6	580025	582109	+	DDB_G0291590	rexo1	similar to S. cerevisiae REX1 or RNH70%2C a 3%27-5%27 RNA exonuclease
chr6	582226	582829	-	DDB_G0291618	DDB_G0291618	contains an N-terminal signal peptide
chr6	583710	584099	-	DDB_G0291646	DDB_G0291646	NA
chr6	584708	585955	+	DDB_G0291592	DDB_G0291592	NA
chr6	586137	586210	+	DDB_G0295301	tRNA-Val-AAC-20	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr6	587234	587769	-	DDB_G0291594	colA_ps5	putative pseudogene%3B small fragment similar to the large colossin A gene %3Ca href%3D%22%2Fgene%2FDDB_G0279833%22%3EcolA%3C%2Fa%3E
chr6	588031	589494	+	DDB_G0291596	wdr13	putative ortholog of H. sapiens WDR13
chr6	590338	592187	+	DDB_G0291598	DDB_G0291598	NA
chr6	592384	593819	-	DDB_G0291600	ldpA	contains 3 predicted transmembrane domains
chr6	594807	595355	+	DDB_G0291602	DDB_G0291602	NA
chr6	595950	598979	+	DDB_G0291604	DDB_G0291604	similar to polyketide synthases%2C but only about one third of the size
chr6	599555	600876	-	DDB_G0291686	DDB_G0291686_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	601031	605468	-	DDB_G0291688	DDB_G0291688_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	604764	604843	-	DDB_G0295469	tRNA-Leu-UAG-3	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	606324	609491	-	DDB_G0291620	DDB_G0291620_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	610016	610957	-	DDB_G0291692	DDB_G0291692_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	611564	612898	+	DDB_G0291696	DDB_G0291696_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	613952	616504	-	DDB_G0291694	DDB_G0291694	NA
chr6	619891	620662	-	DDB_G0295711	ap1s2	putative ortholog of adapter-related protein complex 1 sigma 2 subunit
chr6	620919	621509	+	DDB_G0295709	ufm1	ortholog of human ufm1
chr6	621820	624284	-	DDB_G0295705	DDB_G0295705	NA
chr6	624702	626876	-	DDB_G0295707	gtaP	has 18 amino acids between the two CX2C motifs
chr6	636558	641010	+	DDB_G0295483	DDB_G0295483	similar to H. sapiens C13orf18%3B RUN domains are predicted to play roles in Ras-like GTPase signaling pathways
chr6	641379	643436	+	DDB_G0291708	guf1	ortholog of H. sapiens and S. cerevisiae GUF1%2C a mitochondrial GTP binding protein believed to be involved in protein biosynthesis
chr6	643919	644794	+	DDB_G0291706	DDB_G0291706	NA
chr6	645330	646436	-	DDB_G0291704	DDB_G0291704	NA
chr6	646777	648267	-	DDB_G0291712	DDB_G0291712	NA
chr6	648952	656982	-	DDB_G0291710	roco10	member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases%3B contains RhoGAP%2C LRR%2C Roc%2C COR%2C RGS (regulator of G-protein signaling)%2C Kelch repeats%2C and protein kinase domains
chr6	657386	661533	+	DDB_G0291702	cyp520B1	NA
chr6	663460	665912	-	DDB_G0291700	DDB_G0291700	NA
chr6	667903	672401	+	DDB_G0291714	abcB3	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr6	672553	673128	-	DDB_G0291734	ppil3	peptidyl-prolyl cis-trans isomerase (PPIase) accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr6	673796	675024	-	DDB_G0291770	DDB_G0291770_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291740%22%3EDDB_G0291740%3C%2Fa%3E
chr6	677353	677943	+	DDB_G0291738	rabG1	NA
chr6	678305	679554	-	DDB_G0291740	DDB_G0291740	NA
chr6	680092	681027	-	DDB_G0291742	DDB_G0291742_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0291740%22%3EDDB_G0291740%3C%2Fa%3E
chr6	681611	684737	-	DDB_G0291744	DDB_G0291744	NA
chr6	685440	686289	+	DDB_G0291748	DDB_G0291748	NA
chr6	686426	687387	-	DDB_G0291750	mnd1	conserved protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair
chr6	688164	692478	+	DDB_G0291752	smc1	functions in chromosome dynamics%3B heterodimerizes with smc3
chr6	693935	694660	-	DDB_G0291754	DDB_G0291754	NA
chr6	695138	696660	-	DDB_G0291756	gshB	catalyzes the reaction ATP %2B gamma-L-glutamyl-L-cysteine %2B glycine %3D ADP %2B phosphate %2B glutathione in the synthesis of glutathione (GSH)
chr6	697440	698900	+	DDB_G0291758	DDB_G0291758	NA
chr6	699835	701287	+	DDB_G0291772	DDB_G0291772	NA
chr6	701991	702857	+	DDB_G0291760	DDB_G0291760	NA
chr6	703802	704725	-	DDB_G0291774	DDB_G0291774	NA
chr6	704842	705944	+	DDB_G0291764	DDB_G0291764	related to ribonucleotide reductase small subunit%3B missing about 25%25 of the protein at the carboxyl terminus%2C also missing a histidine residue required for iron center formation
chr6	707563	708799	+	DDB_G0291766	DDB_G0291766	NA
chr6	709621	709860	+	DDB_G0291778	DDB_G0291778	NA
chr6	711008	711934	+	DDB_G0291732	DDB_G0291732	belongs to the NADP_Rossman superfamily%3B similar to human NMRAL1%3B A. nidulans nmrA is a transcriptional regulator involved in nitrogen metabolite repression
chr6	712314	713687	-	DDB_G0291730	DDB_G0291730	NA
chr6	714429	716752	+	DDB_G0291728	arpE	ortholog of the conserved actin related protein  ARP5%2C in mammalian named ACTR5%3B the yeast protein is a nuclear actin-related protein involved in chromatin remodeling%3Cbr%2F%3E %3Cb%3ENomenclature conflict:%3C%2Fb%3E Do not confuse this gene with arcB%2C the 34 kDa component of the Arp2%2FArp3 complex.
chr6	716979	717785	-	DDB_G0291726	DDB_G0291726	NA
chr6	718700	719132	-	DDB_G0291724	DDB_G0291724_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0279121%22%3EDDB_G0279121%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0268734%22%3EDDB_G0268734%3C%2Fa%3E
chr6	719367	720881	-	DDB_G0291722	DDB_G0291722	NA
chr6	721305	722819	-	DDB_G0291720	DDB_G0291720	NA
chr6	724492	726026	+	DDB_G0291718	DDB_G0291718	NA
chr6	726193	728514	-	DDB_G0291716	DDB_G0291716	NA
chr6	730635	732579	-	DDB_G0291768	DDB_G0291768	NA
chr6	736206	736848	+	DDB_G0291786	DDB_G0291786	NA
chr6	737175	738949	+	DDB_G0291780	wbp1	subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of S. cerevisiae WBP1 and human OST48%3B contains one C-terminal transmembrane domain and an N-terminal signal peptide
chr6	739204	742356	+	DDB_G0291782	DDB_G0291782	NA
chr6	743770	745147	-	DDB_G0291784	DDB_G0291784_ps	putative pseudogene%3B similar to a small family of D. discoideum genes%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283103%22%3EDDB_G0283103%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0270532%22%3EDDB_G0270532%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0283215%22%3EDDB_G0283215%3C%2Fa%3E
chr6	747483	748930	+	DDB_G0291790	DDB_G0291790_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0291782%22%3EDDB_G0291782%3C%2Fa%3E  and %3Ca href%3D%22%2Fgene%2FDDB_G0291792%22%3EDDB_G0291792%3C%2Fa%3E
chr6	749614	752672	+	DDB_G0291792	DDB_G0291792	NA
chr6	753746	757096	+	DDB_G0291794	ptcL	NA
chr6	757607	760280	+	DDB_G0291796	DDB_G0291796	NA
chr6	762390	766299	+	DDB_G0291798	DDB_G0291798	NA
chr6	766772	768622	-	DDB_G0291848	csn3	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8) 
chr6	768935	769522	-	DDB_G0291800	DDB_G0291800	GFA enzymes catalyze the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione%3B all known members of this family contain 5 strongly conserved cysteine residues
chr6	769784	770335	-	DDB_G0295669	DDB_G0295669	isochorismatase (also: 2%2C3 dihydro-2%2C3 dihydroxybenzoate synthase) catalyses the conversion of isochorismate %2B H%3Csub%3E2%3C%2Fsub%3EO to 2%2C3-dihydroxybenzoate and pyruvate%3B conserved in bacteria%2C fungi%2C amoeba%2C and plants
chr6	770747	772090	-	DDB_G0291802	qtrt1	catalyzes the reaction [tRNA]-guanine %2B queuine %3D [tRNA]-queuine %2B guanine
chr6	773358	774746	+	DDB_G0291804	ddx6	ortholog of H. sapiens DDX6 and S. cerevisiae DHH1 (DExD%2FH-box Helicase)
chr6	775774	777073	-	DDB_G0291852	DDB_G0291852	NA
chr6	777729	780773	-	DDB_G0291806	DDB_G0291806	NA
chr6	781062	783638	-	DDB_G0291808	DDB_G0291808	NA
chr6	784328	786502	-	DDB_G0291810	DDB_G0291810	NA
chr6	787015	789107	-	DDB_G0291854	DDB_G0291854	similar to D. purpureum protein
chr6	791270	794833	+	DDB_G0291812	DDB_G0291812	NA
chr6	795337	803296	+	DDB_G0291788	adprt3	catalyzes ADP-ribosylation%2C a posttranslational protein modification in which the ADP-ribose moiety of NAD is transferred onto specific amino acid side chains of cell surface%2C secreted%2C cytosolic or nuclear proteins 
chr6	804510	805750	+	DDB_G0291814	hao	single hao ortholog in %3Ci%3ED. discoideum%3C%2Fi%3E%2C very similar to mammalian HAO1%2C an enzyme of the glycolate pathway
chr6	805833	806834	-	DDB_G0291816	DDB_G0291816	NA
chr6	808065	810230	+	DDB_G0291818	DDB_G0291818	NA
chr6	810431	811761	-	DDB_G0291820	DDB_G0291820	NA
chr6	812338	815402	+	DDB_G0291836	DDB_G0291836	NA
chr6	815672	819063	-	DDB_G0291838	xpo2	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0291838 is highly similar to cse1 of budding yeast and CAS of metazoans. In yeast this protein has been shown to be essential for the re-export of importin alpha (see Schroeder et al%2C Mol Gen Genet 261%2C 788-795 (1999). CSE stands for %22chromosome segregation%22%3B the gene was originally identified in a screen for mutations causing chromosome disjuction%3B the null is lethal and conditional mutants arrest with incomplete nuclear division (Xiao et al%2C Mol Cell Biol 13%2C 4691 (1993). The importin system is well known to participate in spindle assembly. The ran GEF RCC1 (regulator of chromosome condensation)%2C normally nuclear%2C associates with the chromosomes after nuclear envelope breakdown and stimulates the release of cargoes necessary for spindle construction in the vicinity of the kinetochores. Cse1 is upregulated threefold in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted. Most genes whose products function specifically in cell cycle progression are overexpressed in this strain. RanA%2C ranB%2C and several proteins with RCC1 domains are upregulated by similar factors. This suggests that importins function in mitosis in Dicty as they do in other organisms. DDB_G0291838%2Fcse1 may well be a part of this system. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E
chr6	819813	822073	+	DDB_G0291840	gacEE	NA
chr6	822502	823633	-	DDB_G0291842	DDB_G0291842	putative protein tyrosine kinase%3B similar to S. pombe WEE1%2C inhibitor of mitosis through phosphorylation of cdc2
chr6	825936	827155	+	DDB_G0291822	wdr92	NA
chr6	827281	829158	-	DDB_G0291824	DDB_G0291824	NA
chr6	830929	831277	+	DDB_G0291826	DDB_G0291826	NA
chr6	832120	833064	-	DDB_G0291828	DDB_G0291828	NA
chr6	833386	834358	+	DDB_G0291830	thg1	conserved eukaryotic protein that has been shown in S. cerevisiae to be an essential tRNAHis guanylyltransferase that adds a guanosine residue to the 5%27 end of tRNAHis after transcription and RNase P cleavage%3B conserved domain also known as DUF549 domain
chr6	834929	837238	-	DDB_G0291832	wdr23	highly similar to the human WDR23 protein
chr6	838074	838444	+	DDB_G0291834	cpiA	similar to animal and plant cystatin A1%3B member of the stefin family of cysteine protease inhibitors
chr6	838751	840844	-	DDB_G0291844	DDB_G0291844	NA
chr6	841885	842646	+	DDB_G0291952	DDB_G0291952	expressed in prespore cells
chr6	842775	843868	-	DDB_G0295741	DDB_G0295741	contains a C-terminal FR47-like N-acyltransferase-like domain%3B has similarity to H. sapiens glycine N-acyltransferase-like protein 1 (GLYATL1)
chr6	844628	845631	+	DDB_G0291864	rps8	protein component of the small (40S) ribosomal subunit
chr6	846677	849070	-	DDB_G0291860	DDB_G0291860	has a short region of similarity with CARD3 (caspase recruitment domain family%2C member 3)
chr6	849824	850186	+	DDB_G0291866	ndufab1	similar to mitochondrial matrix acyl carrier protein and the animal NADH dehydrogenase (ubiquinone) 1%2C alpha%2Fbeta subcomplex 1%2C which is the carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria
chr6	850606	851622	+	DDB_G0291868	rfc2	ortholog of %3Ci%3EH. sapiens%3C%2Fi%3E RFC2 (40 kDa subunit) and %3Ci%3ES. cerevisiae%3C%2Fi%3E RFC2
chr6	852689	853474	+	DDB_G0291870	rpl13	protein component of the large (60S) ribosomal subunit
chr6	855161	857960	+	DDB_G0291872	DDB_G0291872	NA
chr6	858095	858430	-	DDB_G0291874	DDB_G0291874	NA
chr6	859158	859228	+	DDB_G0295303	tRNA-Gly-GCC-14	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr6	860099	860854	+	DDB_G0291954	DDB_G0291954_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	861379	863700	+	DDB_G0291878	DDB_G0291878_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	864825	865061	+	DDB_G0291956	DDB_G0291956_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	866031	869858	+	DDB_G0291958	DDB_G0291958_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	870523	871242	+	DDB_G0291960	DDB_G0291960_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	872034	874343	+	DDB_G0291940	DDB_G0291940_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	874531	875214	+	DDB_G0291880	DDB_G0291880_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	875439	876122	+	DDB_G0291882	DDB_G0291882_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	876601	877680	+	DDB_G0291962	DDB_G0291962_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	878204	881383	+	DDB_G0291884	DDB_G0291884_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	881755	883220	+	DDB_G0291886	DDB_G0291886_ps	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293836%22%3E%3Ci%3EDDB_G0293836%3C%2Fi%3E%3C%2Fa%3E
chr6	883760	885299	+	DDB_G0295691	DDB_G0295691	shares a region of similarity with proteins of unknown functions%3B contains eight predicted transmembrane domains
chr6	886219	887767	+	DDB_G0291888	DDB_G0291888	NA
chr6	889796	892606	+	DDB_G0291858	vatM	ortholog of the mammalian V-type proton ATPase 116 kDa subunit a%2C the transmembrane subunit of the vacuolar ATP synthase that generates an acidic environment in several intracellular compartments%3B V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes%3B this protein is part of the V0 complex
chr6	893019	897555	-	DDB_G0291964	DDB_G0291964_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	898266	898339	-	DDB_G0295467	tRNA-Phe-GAA-16	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	898616	899329	+	DDB_G0291942	DDB_G0291942	NA
chr6	899533	900456	+	DDB_G0291892	DDB_G0291892	NA
chr6	900574	903574	-	DDB_G0291894	ncapH2	component of the condensin II complex%2C which is involved in physical rigidity of the chromatid axis
chr6	904350	906031	+	DDB_G0291896	DDB_G0291896	weakly similar to mammalian NASP (Nuclear Autoantigenic Sperm Protein)%2C a histone chaperone required for DNA replication%2C normal cell cycle progression and cell proliferation%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0291896 is similar (first blast hit%2C both ways) to the N1%2FN2 protein of Xenopus%2C in humans known as NASP (nuclear autoantigenic sperm protein)%2C a histone chaperone found in all dividing cells and implicated in chromatin assembly (see Wang et al%2C NAR 36%2C 5763-5772 (2008). NASP is required for cell cycle progression and is upregulated in a variety of cancers (see Alekseev et al%2C Reproductive Biology and Endocrinology 7%2C 45%2C 2009).%3Cbr%3E DDB_G0291896 is overexpressed threefold (p%3C2e-72) in a Dicty strain in which the retinoblastoma-like protein rblA has been disrupted. Most genes with functions in cell cycle progression are overexpressed in this strain%2C and most overexpressed genes have identifiable cell cycle functions (Doquang et al.%2C in preparation)%3B these include other genes involved in chromatin assembly such as chromatin assembly factor 1 subunits A%2C B and p55 (DDB_G0287815%2C DDB_G0269800 and rbbD%2C respectively) and the histone chaperone asf1. It appears plausible that DDB_G0291896 has a cell cycle function in Dicty%2C perhaps as a histone chaperone. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E
chr6	906094	909205	-	DDB_G0291930	DDB_G0291930_ps	putative pseudogene%3B similar to a family of Dictyostelium genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0272977%22%3EDDB_G0272977%3C%2Fa%3E
chr6	909614	909859	+	DDB_G0291898	DDB_G0291898	NA
chr6	911015	911794	+	DDB_G0291900	DDB_G0291900	NA
chr6	911883	913067	-	DDB_G0291902	DDB_G0291902	NA
chr6	915091	916881	+	DDB_G0291904	DDB_G0291904	NA
chr6	917876	921680	+	DDB_G0291906	DDB_G0291906	NA
chr6	921791	923035	-	DDB_G0291908	DDB_G0291908	NA
chr6	923283	924659	+	DDB_G0291910	bcs1lB	conserved mitochondrial chaperone necessary for the assembly of mitochondrial respiratory chain complex III%3B %3Ci%3E Dictyostelium%3C%2Fi%3E has a second BCS1-like protein%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0289135%22%3E%3Ci%3Ebcs1lA%3C%2Fi%3E%3C%2Fa%3E
chr6	926086	930902	+	DDB_G0291856	gerD	similar to celA and celB
chr6	931229	932834	-	DDB_G0291912	DDB_G0291912	catalyzes the release of a C-terminal amino acid with broad specificity
chr6	933442	933866	-	DDB_G0291914	DDB_G0291914	NA
chr6	934204	936568	-	DDB_G0291946	DDB_G0291946	NA
chr6	936889	937463	-	DDB_G0291948	DDB_G0291948	belongs to the UPF0539 family%3B similar to human C7orf59
chr6	937759	940485	-	DDB_G0291934	DDB_G0291934	NA
chr6	940721	942478	-	DDB_G0291916	argJ	catalyzes the reactions acetyl-CoA %2B L-glutamate %3D CoA %2B N-acetyl-L-glutamate %3Cb%3Eand%3C%2Fb%3E N%3Csub%3E2%3C%2Fsub%3E-acetyl-L-ornithine %2B L-glutamate %3D L-ornithine %2B N-acetyl-L-glutamate
chr6	943654	945838	+	DDB_G0291918	DDB_G0291918	putative protein serine%2Fthreonine kinase%2C CAMK group%3B kinase domain is similar to those of mammalian death-associated protein kinases (DAPK)
chr6	946580	947959	+	DDB_G0291920	DDB_G0291920	NA
chr6	948054	950082	-	DDB_G0291966	DDB_G0291966	NA
chr6	950884	951927	+	DDB_G0291922	taz	ortholog of S. cerevisiae TAZ1 and H. sapiens tafazzin%2C implicated in Barth syndrome
chr6	952138	953161	+	DDB_G0291924	DDB_G0291924	NA
chr6	954736	956486	-	DDB_G0291862	rpl3	protein component of the large (60S) ribosomal subunit%3B ribosomal protein L3 homolog
chr6	959253	960582	-	DDB_G0291926	DDB_G0291926	weakly similar ro S. cerevisiae Arc1%2C a protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases%2C delivering tRNA to them%2C stimulating catalysis%2C and ensuring their localization to the cytoplasm
chr6	961035	961952	+	DDB_G0291928	ubqI	NA
chr6	962283	963440	+	DDB_G0291936	DDB_G0291936	NA
chr6	964334	965625	+	DDB_G0291938	DDB_G0291938	NA
chr6	966638	968696	+	DDB_G0291968	DDB_G0291968	NA
chr6	968881	972189	+	DDB_G0292166	DDB_G0292166	NA
chr6	972420	975716	-	DDB_G0291996	gxcU	NA
chr6	977829	980754	-	DDB_G0291972	culA	very similar to mammalian cullin 1 (CUL1)%3B involved in ubiquitin-mediated protein degradation%2C which in %3Ci%3EDictyostelium%3C%2Fi%3E controls PKA function and regulates cell differentiation
chr6	982514	984910	-	DDB_G0291998	naglu	catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides%3B mutated in patients with mucopolysaccharidosis type IIIB (Sanfilippo syndrome type B)%2C a lysosomal storage disorder
chr6	988440	992753	+	DDB_G0291978	xacA	contains a RhoGAP domain%2C an SH3 domain%2C and two RhoGEF domains separated by a PH domain
chr6	992955	995071	-	DDB_G0292000	DDB_G0292000	NA
chr6	996494	997917	-	DDB_G0292002	ergic3	conserved protein that might be involved in transport between endoplasmic reticulum and Golgi%3B contains two putative transmembrane domains 
chr6	999481	1004691	+	DDB_G0292004	docC	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0292004 (DockC) is threefold overexpressed in a dicty strain lacking the retinoblastoma-like gene rblA (Doquang et al%2C in preparation). Most genes involved in cell cycle progression%2C but relatively few other genes%2C are upregulated in this strain%2C suggesting that DockC has a role in the cell cycle%2C possibly in cytokinesis. DockA%2C B and D are not regulated by rblA. %3Ci%3EHarry MacWilliams%2C May 2009%3C%2Fi%3E%3Cbr%3E A c-terminal GFP fusion localizes to mitochondria. Rod-shaped and round mitochondria are seen in different cells. Cells with round mitochondria tend to be brighter%2C suggesting that docC might influence the rod to round transition. %3Ci%3EHarry MacWilliams%2C February 2011%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FdocC%22%3E There is an image and more information on the wiki page%3C%2Fa%3E
chr6	1004992	1005957	+	DDB_G0292006	DDB_G0292006	NA
chr6	1006156	1010307	-	DDB_G0292154	DDB_G0292154	NA
chr6	1010717	1013122	+	DDB_G0292008	DDB_G0292008	NA
chr6	1013913	1013985	-	DDB_G0295465	tRNA-Ile-AAU-17	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1014321	1016654	+	DDB_G0292010	DDB_G0292010	NA
chr6	1016886	1018043	+	DDB_G0292012	DDB_G0292012	belongs to the GNAT family%3B conserved in fungi
chr6	1018381	1020982	-	DDB_G0292014	psiK	contains a PA14 (anthrax protection antigen) domain and 6 Dictyostelium (CTDC) repeats
chr6	1023224	1025099	-	DDB_G0291982	psiA	secreted glycoprotein that induces prespore cell differentiation and prespore cell division
chr6	1027245	1030001	+	DDB_G0292016	DDB_G0292016	NA
chr6	1030321	1031368	+	DDB_G0292018	DDB_G0292018_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0270600%22%3EDDB_G0270600%3C%2Fa%3E
chr6	1032623	1035332	-	DDB_G0292020	DDB_G0292020	NA
chr6	1035856	1037445	-	DDB_G0292022	ubr7	NA
chr6	1039810	1040608	+	DDB_G0292024	DDB_G0292024	dual specificity phosphatases remove phosphate groups from tyrosine and serine%2Fthreonine residues 
chr6	1041751	1042269	+	DDB_G0291990	febA	similar to human EIF4EBP1
chr6	1044327	1044740	-	DDB_G0291970	cofB	coding region identical to cofA%2C the 15 kDa actin severing protein
chr6	1044809	1044891	-	DDB_G0295463	tRNA-Leu-UAA-18	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1046109	1048990	+	DDB_G0292028	DDB_G0292028	NA
chr6	1049058	1050190	-	DDB_G0292030	DDB_G0292030	NA
chr6	1051056	1056184	+	DDB_G0292032	DDB_G0292032	NA
chr6	1056383	1057383	-	DDB_G0291992	DDB_G0291992	no known homologs%3B REMI mutant forms aberrant fruiting bodies (see %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0291992%22%3Ecommunity annotation%3C%2Fa%3E) 
chr6	1058459	1059755	+	DDB_G0292034	mcfP	ortholog of Grave disease carrier protein (slc25a16)%2C belongs to the substrate carrier proteins that are involved in transport of molecules across the mitochondrial membrane%3B may transport coenzyme A %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr6	1059972	1061543	-	DDB_G0292036	ric8	similar to human RIC8A (synembryn-A)%3B non-receptor guanine nucleotide exchange factor for G%26alpha%3B protein%3B important for chemotaxis and development
chr6	1062124	1062936	+	DDB_G0292038	DDB_G0292038	conserved in bacteria%3B predicted to have a structural domain found in several acyl-CoA acyltransferase enzymes%3B contains a predicted peroxisomal targeting signal
chr6	1063213	1064811	+	DDB_G0292040	hemG	catalyzes the conversion of protoporphyrinogen-IX to protoporphyrin-IX in heme biosynthesis
chr6	1065129	1065905	+	DDB_G0292202	DDB_G0292202	NA
chr6	1066047	1068473	-	DDB_G0292042	DDB_G0292042	very similar to plant and fungi GMC oxidoreductases
chr6	1069821	1071514	+	DDB_G0292044	DDB_G0292044	NA
chr6	1071921	1081998	+	DDB_G0292046	DDB_G0292046	NA
chr6	1082258	1083195	+	DDB_G0292048	DDB_G0292048	NA
chr6	1087783	1089433	+	DDB_G0292168	cyp516A1	NA
chr6	1089711	1092837	-	DDB_G0291980	abcA9	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr6	1093282	1096098	+	DDB_G0291994	abcA1	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr6	1097223	1097304	-	DDB_G0295461	tRNA-Ser-UGA-15	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1099513	1100944	+	DDB_G0292052	sec13	component of the Nup84 nuclear pore complex and the COPII (coat protein complex II) involved in ER to Golgi transport
chr6	1101689	1103010	+	DDB_G0292054	DDB_G0292054	contains 3 CBM49 (carbohydrate-binding module) domains
chr6	1105862	1112768	+	DDB_G0291974	docA	similar to H. sapiens DOCK180 protein%3B contains an SH3 domain
chr6	1113786	1114833	+	DDB_G0292170	DDB_G0292170	NA
chr6	1115547	1121605	+	DDB_G0292056	DDB_G0292056	NA
chr6	1121898	1123685	-	DDB_G0292058	DDB_G0292058	contains a weak tweety (tty) domain%2C which is of unknown function
chr6	1124940	1125021	+	DDB_G0295305	tRNA-Ser-UGA-9	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1125152	1126000	+	DDB_G0292060	DDB_G0292060_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1126179	1127540	+	DDB_G0292062	DDB_G0292062_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1128211	1129275	-	DDB_G0292172	DDB_G0292172_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	1129630	1129711	-	DDB_G0295459	tRNA-Ser-UGA-14	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1130560	1131894	+	DDB_G0292174	DDB_G0292174_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	1133095	1133176	-	DDB_G0295457	tRNA-Ser-UGA-13	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1134651	1136344	+	DDB_G0292064	fscF	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr6	1137104	1138883	+	DDB_G0292156	fscG	has similarity to G-protein-coupled receptors%2C frizzled and smoothened like proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr6	1139831	1140547	+	DDB_G0292158	DDB_G0292158	NA
chr6	1141212	1144129	+	DDB_G0292066	ncapH	component of the condensin I complex%2C required for conversion of interphase chromatin into mitotic condensed chromosomes
chr6	1144263	1147638	-	DDB_G0292068	frpA	contains two N-terminal calponin homology (CH) domains%2C which is similar to fimbrins%2C and a long unrelated C-terminal tail
chr6	1148827	1151310	-	DDB_G0292070	DDB_G0292070	contains an F-box domain and 6 Kelch repeats
chr6	1153510	1154993	+	DDB_G0292072	fdfT	catalyzes the reaction farnesyl diphosphate %3C%3D%3E diphosphate %2B presqualene diphosphate
chr6	1155156	1155897	-	DDB_G0292074	commd1	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr6	1156278	1157333	+	DDB_G0292076	DDB_G0292076	NA
chr6	1157682	1157849	-	DDB_G0292078	DDB_G0292078	NA
chr6	1159633	1160758	+	DDB_G0292080	DDB_G0292080	NA
chr6	1161454	1161954	-	DDB_G0292084	DDB_G0292084_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0292096%22%3EDDB_G0292096%3C%2Fa%3E
chr6	1163265	1164257	-	DDB_G0292178	DDB_G0292178_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0292094%22%3EDDB_G0292094%3C%2Fa%3E
chr6	1164954	1166069	+	DDB_G0292180	mybT	contains one Myb DNA-binding domain 
chr6	1166334	1166713	+	DDB_G0292086	DDB_G0292086_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0293590%22%3EDDB_G0293590%3C%2Fa%3E 
chr6	1166986	1167321	-	DDB_G0292088	DDB_G0292088	NA
chr6	1167971	1168477	-	DDB_G0292090	DDB_G0292090_ps	putative pseudogene%3B fragment%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0292096%22%3EDDB_G0292096%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0277355%22%3EDDB_G0277355%3C%2Fa%3E
chr6	1169702	1170070	+	DDB_G0292092	DDB_G0292092	NA
chr6	1170735	1171772	-	DDB_G0292094	DDB_G0292094	NA
chr6	1172608	1174303	+	DDB_G0292182	mybR	contains one Myb DNA-binding domain
chr6	1176701	1177843	-	DDB_G0292096	DDB_G0292096	contains a cytidine and deoxycytidylate deaminase zinc-binding region%3B contains a carbohydrate-binding domain%3B contains a predicted signal peptide
chr6	1180007	1183816	+	DDB_G0292098	DDB_G0292098	NA
chr6	1184434	1186464	-	DDB_G0292100	fscH	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr6	1187184	1188485	-	DDB_G0292102	fscJ	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr6	1190069	1191163	+	DDB_G0292104	tkrA	catalyzes the reaction D-gluconate %2B NADP%3Csup%3E%2B%3C%2Fsup%3E %3C%3D%3E 2-dehydro-D-gluconate %2B NADPH %2B H%3Csup%3E%2B%3C%2Fsup%3E
chr6	1191356	1192342	+	DDB_G0292106	DDB_G0292106	NA
chr6	1192584	1195073	-	DDB_G0292108	DDB_G0292108	NA
chr6	1196812	1200751	+	DDB_G0292186	DDB_G0292186	predicted to contain one transmembrane domain near the carboxyl terminus
chr6	1201167	1202370	+	DDB_G0292110	DDB_G0292110	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr6	1203261	1204837	+	DDB_G0292112	galK	phosphorylates D-galactose to alpha-D-galactose 1-phosphate
chr6	1206606	1210418	+	DDB_G0291984	DDB_G0291984	contains two SH3 domains and one glutaminase domain
chr6	1210911	1212299	+	DDB_G0291976	racD	NA
chr6	1213027	1216562	+	DDB_G0291986	xpo7	ortholog of H. sapiens XPO7 involved in  protein export from nucleus
chr6	1217707	1218333	-	DDB_G0292114	DDB_G0292114	NA
chr6	1219275	1220362	-	DDB_G0292116	DDB_G0292116	belongs to the short-chain dehydrogenases%2Freductases family%3B similar to human HSDL2 (Hydroxysteroid dehydrogenase-like protein 2)
chr6	1220852	1222575	+	DDB_G0292118	alg11	CAZy family GT4%3B catalyzes N-linked mannosylation
chr6	1222744	1226550	-	DDB_G0292120	cnrK	identified as a suppressor of smlA null mutant cnr11
chr6	1227398	1228417	+	DDB_G0292122	psmA2	subunit of an endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr6	1228678	1232537	-	DDB_G0292124	DDB_G0292124	NA
chr6	1233335	1239538	-	DDB_G0292128	DDB_G0292128	NA
chr6	1240457	1244236	+	DDB_G0292130	blm	E. coli ATP-dependent DNA helicase RecQ is involved in genome maintenance%3B this is the ortholog of the H. sapiens Bloom syndrome protein%3B defects in BLM cause genetic instability%2C including a high level of sister chromatid exchanges%2C associated with a greatly increased predisposition to a wide range of cancers
chr6	1244360	1246685	-	DDB_G0292132	DDB_G0292132	members of the multi antimicrobial extrusion (MATE) family function as drug%2Fsodium antiporters and are found in bacteria%2C archaea and eukaryotes%3B these proteins are predicted to have 12 alpha-helical transmembrane regions
chr6	1247461	1248649	-	DDB_G0292134	bub3	ortholog of BUB3%2C a mitotic checkpoint protein%3B in human a kinetochore protein that interacts with BUB1
chr6	1249171	1249530	-	DDB_G0292136	hatC	almost identical to hisactophilin I and II (hatA and hatB)%2C histidine-rich%2C pH-dependent%2C actin binding proteins
chr6	1250562	1250632	-	DDB_G0295455	tRNA-Pro-UGG-16	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr6	1250981	1251624	+	DDB_G0292138	DDB_G0292138	NA
chr6	1251863	1252538	-	DDB_G0291988	if1	belongs to the wider family of mitochondrial F1F(o)-ATPase inhibitors%3B contains a conserved ATPIF1 domain
chr6	1253197	1255449	-	DDB_G0292188	DDB_G0292188	conserved hypothetical %3Ci%3EDictyostelium%3C%2Fi%3E protein%3B contains a weak von Willebrand factor%2C type A domain
chr6	1256247	1257987	-	DDB_G0292140	DDB_G0292140	NA
chr6	1258240	1259280	+	DDB_G0292142	cepA	localizes to the centrosomal core structure
chr6	1259597	1262431	-	DDB_G0292190	DDB_G0292190	NA
chr6	1263546	1264675	+	DDB_G0292160	DDB_G0292160	NA
chr6	1266213	1267748	+	DDB_G0292204	fscC	similar to G-protein-coupled receptors and to frizzled and smoothened proteins%2C but does not contain the N-terminal CRD (cysteine rich domain) domain%3B predicted to have 7 transmembrane domains and a putative signal peptide
chr6	1267882	1268940	-	DDB_G0292144	DDB_G0292144	NA
chr6	1269573	1271111	-	DDB_G0292162	DDB_G0292162	contains 12 putative transmembrane domains
chr6	1271733	1273001	+	DDB_G0292146	DDB_G0292146	NA
chr6	1273206	1275068	-	DDB_G0292148	DDB_G0292148	NA
chr6	1275799	1277823	-	DDB_G0292192	DDB_G0292192	NA
chr6	1279409	1281346	+	DDB_G0292194	DDB_G0292194	NA
chr6	1282462	1285363	-	DDB_G0292196	DDB_G0292196	NA
chr6	1289254	1293574	+	DDB_G0292150	ak1	atypical protein serine%2Fthreonine kinase%2C contains an N-terminal ArfGap domain and a C-terminal Alpha kinase domain
chr6	1294776	1298066	+	DDB_G0292152	cdc7	similar to %3Ci%3ES. cerevisiae%3C%2Fi%3E cell division control protein 7 (CDC7)%2C a serine%2Fthreonine kinase required for mitosis and meiosis
chr6	1298736	1299300	-	DDB_G0292198	DDB_G0292198_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1299996	1300066	-	DDB_G0295453	tRNA-Pro-UGG-15	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr6	1300465	1301905	-	DDB_G0292250	sqrdl	ortholog of the conserved sulfide quinone reductase-like protein%3B in S. pombe%2C this oxidoreductase is involved in mitochondrial sulfide oxidation
chr6	1302637	1306509	-	DDB_G0292252	DDB_G0292252	weakly similar to H. sapiens C1orf103
chr6	1307362	1308597	+	DDB_G0292258	DDB_G0292258	NA
chr6	1308810	1309757	-	DDB_G0292254	DDB_G0292254	NA
chr6	1311188	1320534	+	DDB_G0292230	DDB_G0292230	NA
chr6	1321609	1321728	-	DDB_G0292228	DDB_G0292228	NA
chr6	1321993	1322066	-	DDB_G0295451	tRNA-Val-AAC-21	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1323250	1324581	+	DDB_G0292226	DDB_G0292226	NA
chr6	1325480	1325845	+	DDB_G0292224	ecmG	expressed in pstAO cells%3B expression is decreased in %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281381%22%3E%3Ci%3EdstA%3C%2Fi%3E%3C%2Fa%3E cells
chr6	1326474	1326839	+	DDB_G0292222	ecmI	expression is decreased in %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281381%22%3E%3Ci%3EdstA%3C%2Fi%3E%3C%2Fa%3E cells
chr6	1327483	1327851	+	DDB_G0292220	ecmH	expression is decreased in %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281381%22%3E%3Ci%3EdstA%3C%2Fi%3E%3C%2Fa%3E cells
chr6	1328404	1328772	+	DDB_G0292218	st15	similar to beta-1%2C4-endoglucanase%3B expressed in pstO cells%3B expression is decreased in %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0281381%22%3E%3Ci%3EdstA%3C%2Fi%3E%3C%2Fa%3E cells
chr6	1328996	1330184	-	DDB_G0292216	bxdc1	ortholog of S. cerevisiae RPF2 and H. sapiens BXDC1%2C a nucleolar protein involved in the assembly of the large ribosomal subunit
chr6	1330581	1333346	-	DDB_G0292214	DDB_G0292214	similar to tipA
chr6	1334023	1335234	+	DDB_G0292212	vps26l	ortholog of H. sapiens DSCR3%2C the Down syndrome critical region gene 3
chr6	1335430	1336489	-	DDB_G0292210	DDB_G0292210	NA
chr6	1336984	1337310	-	DDB_G0292208	DDB_G0292208	contains two transmembrane domains
chr6	1339608	1340092	+	DDB_G0292256	DDB_G0292256	NA
chr6	1340609	1340914	-	DDB_G0292232	DDB_G0292232	NA
chr6	1341999	1347696	-	DDB_G0292234	DDB_G0292234	NA
chr6	1348680	1349786	+	DDB_G0292236	DDB_G0292236	conserved hypothetical protein%3B contains a putative signal peptide
chr6	1350474	1354123	+	DDB_G0349136	DDB_G0349136	NA
chr6	1354305	1354870	+	DDB_G0349138	DDB_G0349138	NA
chr6	1355092	1358264	-	DDB_G0292206	manA	NA
chr6	1358978	1360309	+	DDB_G0292240	DDB_G0292240	NA
chr6	1360709	1367727	-	DDB_G0292242	taf1	ortholog of H. sapiens and S. cerevisiae TAF1%3B an atypical TAF1 family protein kinase and contains a bromodomain%3B putative HAF group protein (histone acetyltransferase)
chr6	1368967	1370237	+	DDB_G0292244	rpb3	component of the RNA polymerase II complex%3B ortholog of S. cerevisiae RPB3
chr6	1370987	1372138	+	DDB_G0292246	DDB_G0292246	NA
chr6	1372308	1373349	-	DDB_G0292248	DDB_G0292248	expressed in pstO cells and in pstO cells and upper cup during culmination
chr6	1373916	1378288	+	DDB_G0292260	DDB_G0292260_RTE	partial ORF1 and ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	1374085	1374157	+	DDB_G0295307	tRNA-Ile-AAU-12	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1379067	1381564	-	DDB_G0292272	DDB_G0292272_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr6	1381886	1382979	+	DDB_G0292274	DDB_G0292274_ps	NA
chr6	1383635	1384645	+	DDB_G0292280	DDB_G0292280_ps	putative pseudogene%3B similar to a protein family including %3Ca href%3D%22%2Fgene%2FDDB_G0279871%22%3EDDB_G0279871%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0279891%22%3EDDB_G0279891%3C%2Fa%3E
chr6	1385822	1387600	+	DDB_G0292282	DDB_G0292282	NA
chr6	1387934	1389603	+	DDB_G0292284	DDB_G0292284	NA
chr6	1390052	1393777	+	DDB_G0292286	DDB_G0292286	NA
chr6	1393939	1394946	-	DDB_G0292288	DDB_G0292288	NA
chr6	1396696	1399005	+	DDB_G0292290	DDB_G0292290	NA
chr6	1399162	1401335	-	DDB_G0292292	DDB_G0292292	NA
chr6	1403334	1404843	+	DDB_G0292270	comG	catalyzes the reaction aldehyde %2B NAD%2B %2B H%3Csub%3E2%3C%2Fsub%3EO %3D an acid %2B NADH %2B H%2B
chr6	1406177	1412714	+	DDB_G0292358	ino80	similar to S. cerevisiae INO80%2C an ATPase that forms a large complex%2C containing actin and several actin-related proteins%2C that has chromatin remodeling activity and 3%27 to 5%27 DNA helicase activity in vitro%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr6	1412890	1413984	-	DDB_G0292294	hemE	catalyzes the reaction uroporphyrinogen III %3C%3D%3E coproporphyrinogen %2B 4 CO%3Csub%3E2%3C%2Fsub%3E in heme biosynthesis
chr6	1414792	1417980	+	DDB_G0292296	xpc	putative ortholog of H. sapiens XPC and S. cerevisiae RAD4
chr6	1420214	1421897	+	DDB_G0292354	DDB_G0292354	putative protein serine%2Fthreonine kinase%2C TTBK family%3B similar to casein kinase%3B similar to mammalian tau-tubulin kinase (TTBK)%2C which phosphorylates the microtubule-associated protein tau implicated in Alzheimer%27s disease
chr6	1422661	1423817	+	DDB_G0292268	rab2A	similar to N. tabacum rab2
chr6	1424473	1425495	-	DDB_G0292298	DDB_G0292298	NA
chr6	1426160	1427984	+	DDB_G0292300	rsmM	NA
chr6	1428528	1430846	-	DDB_G0292302	DDB_G0292302	NA
chr6	1433748	1437035	-	DDB_G0292304	mrkA	CAMKL family protein kinase%2C similar to MARK kinases%2C SNF1 kinases%2C and AMPK kinases%3B contains 1 kinase-associated (KA1) domain and 1 UBA domain
chr6	1438508	1440245	+	DDB_G0292306	atp5C1	NA
chr6	1441126	1442403	+	DDB_G0292342	DDB_G0292342	NA
chr6	1442668	1444348	-	DDB_G0292310	psenB	putative catalytic component of the gamma-secretase complex%3B similar to presenilin 2%2C a gene that has been associated with early-onset familial Alzheimer%27s disease
chr6	1444957	1450121	-	DDB_G0292340	DDB_G0292340	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity
chr6	1453608	1453680	+	DDB_G0295309	tRNA-Gln-UUG-13	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1454104	1455853	-	DDB_G0292312	DDB_G0292312	NA
chr6	1457514	1460233	+	DDB_G0292314	gdt7	highly similar to other Dictyostelium GDT proteins%2C however%2C it does not contain a protein kinase domain
chr6	1463619	1469554	+	DDB_G0292262	myoM	unconventional myosin and guanyl-nucleotide exchange factor which acts on Rac1A%2C Rac1B%2C and human Rac1%2C but not on RacC and RacE
chr6	1471614	1472506	+	DDB_G0292318	rsmD	NA
chr6	1472850	1476705	-	DDB_G0292264	nosA	similar to ubiquitin-fusion-degradation protein 2 (UFD2) from Saccharomyces cerevisiae
chr6	1479615	1480727	+	DDB_G0292320	DDB_G0292320	NA
chr6	1481023	1482087	-	DDB_G0292322	DDB_G0292322	NA
chr6	1482971	1483268	+	DDB_G0292360	DDB_G0292360	NA
chr6	1483431	1483970	+	DDB_G0292324	med28	ortholog of the mediator of RNA polymerase II transcription subunit 28%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr6	1484064	1485449	-	DDB_G0292326	gcvT	catalyzes the reaction protein-S-aminomethyldihydrolipoyllysine %2B tetrahydrofolate %3C%3D%3E protein-dihydrolipoyllysine %2B 5%2C10-methylenetetrahydrofolate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr6	1486590	1488689	+	DDB_G0292362	DDB_G0292362	putative ortholog of mammalian thimet oligopeptidase THOP1%2C involved in cytoplasmic peptide degradation%2C including neuropeptides%2C and S. cerevisiae PRD1%2C involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins
chr6	1489407	1490889	-	DDB_G0292328	iliM	similar to bacterial aromatic-ring hydroxylases and fungal monooxygenases%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr6	1491265	1494036	-	DDB_G0292266	amdA	required for spore formation%3B inhibits the formation of aspidocytes%3B catalyzes the reaction AMP %2B H%3Csub%3E2%3C%2Fsub%3EO %3D IMP %2B NH%3Csub%3E3%3C%2Fsub%3E%3Cbr%3E %3Cb%3ENomenclature conflict: %3C%2Fb%3E Do not confuse this gene with amd1%2C encoding S-adenosylmethionine decarboxylase
chr6	1495780	1496322	+	DDB_G0292330	DDB_G0292330	NA
chr6	1496951	1500625	+	DDB_G0292350	DDB_G0292350	kinase domain similar to those of mitogen-activated protein kinases
chr6	1500852	1501412	+	DDB_G0292332	DDB_G0292332	NA
chr6	1502579	1504973	-	DDB_G0292334	DDB_G0292334	the C-terminal of this protein is conserved
chr6	1506515	1508114	-	DDB_G0292364	DDB_G0292364_TE	putative DNA transposon Tdd-4 fragment%3B refer to U57081 for full-length consensus element
chr6	1508214	1510445	-	DDB_G0292352	DDB_G0292352_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr6	1512244	1513479	-	DDB_G0292336	DDB_G0292336	NA
chr6	1514365	1515402	-	DDB_G0292366	DDB_G0292366	NA
chr6	1516008	1516856	+	DDB_G0292368	DDB_G0292368	NA
chr6	1516913	1518719	-	DDB_G0292370	DDB_G0292370_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	1518919	1521774	-	DDB_G0292372	DDB_G0292372_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1522623	1523708	-	DDB_G0292374	DDB_G0292374_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1524225	1527408	-	DDB_G0292338	DDB_G0292338_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1527937	1529016	-	DDB_G0292376	DDB_G0292376_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1529428	1529500	-	DDB_G0295449	tRNA-Ala-AGC-15	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1532417	1533751	+	DDB_G0292516	DDB_G0292516_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	1536171	1539548	-	DDB_G0292394	DDB_G0292394	NA
chr6	1540535	1544093	+	DDB_G0292396	DDB_G0292396	NA
chr6	1544203	1550722	-	DDB_G0292398	psmE4	activator subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr6	1551408	1552211	-	DDB_G0292400	vps2B	putative ortholog of human CHMP2A (Chromatin Modifying Protein 2A) and yeast DID4 (Doa4-Independent Degradation)%2C component of the ESCRT-III complex (endosomal sorting complex required for transport)
chr6	1553006	1553347	+	DDB_G0292518	DDB_G0292518	NA
chr6	1553647	1555474	-	DDB_G0292402	hacl1	putative 2-hydroxyacyl-CoA lyase%3B which cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde
chr6	1556012	1557801	-	DDB_G0292404	sti1	ortholog of S. cerevisiae STI1 and H. sapiens STIP1
chr6	1558648	1559514	+	DDB_G0292406	rab4	similar to H. sapiens rab4B
chr6	1560005	1560838	+	DDB_G0292408	DDB_G0292408	NA
chr6	1561008	1562308	-	DDB_G0292410	DDB_G0292410	similar to %3Ci%3EH. sapiens%3C%2Fi%3E zinc finger CCCH-type containing 15 and %3Ci%3EM. musculus%3C%2Fi%3E immediate early response%2C erythropoietin 4
chr6	1563103	1565321	-	DDB_G0292412	DDB_G0292412	similar to S. cerevisiae and S. pombe TRK1 and TRK2 potassium transporters%3B contains 9 predicted transmembrane domains
chr6	1566054	1568816	-	DDB_G0292414	DDB_G0292414	NA
chr6	1569201	1572480	-	DDB_G0292416	DDB_G0292416	NA
chr6	1574061	1575913	-	DDB_G0292510	drap1	ortholog of Dr1-associated corepressor
chr6	1576374	1578657	-	DDB_G0292418	itfg1	very conserved protein%2C the Dictyostelium protein contains 7 putative FG-GAP repeats%3B conserved protein also known as T-cell immunomodulatory protein%3B contains a putative N-terminal signal peptide and a C-terminal transmembrane domain.
chr6	1579394	1580040	+	DDB_G0292420	mrpl53	protein component of the mitochondrial large ribosomal subunit
chr6	1580488	1582823	-	DDB_G0292422	DDB_G0292422	contains two RNA recognition motifs (RRMs)%2C which are putative RNA binding domains
chr6	1583730	1588013	-	DDB_G0292392	Dd5P3	NA
chr6	1591188	1591934	+	DDB_G0292520	DDB_G0292520	NA
chr6	1592145	1592902	-	DDB_G0292388	rpl27a	protein component of the large (60S) ribosomal subunit
chr6	1593747	1594763	+	DDB_G0292424	DDB_G0292424	NA
chr6	1595140	1596418	-	DDB_G0292426	pitD	belongs to the phosphatidylinositol transfer protein family
chr6	1597521	1601190	-	DDB_G0292524	DDB_G0292524	dymeclin ortholog%2C involoved in Dyggve-Melchior-Clausen syndrome
chr6	1601647	1603185	-	DDB_G0292428	DDB_G0292428	NA
chr6	1603469	1605457	-	DDB_G0294629	DDB_G0294629	NA
chr6	1606038	1606826	-	DDB_G0294627	DDB_G0294627	NA
chr6	1607077	1607319	-	DDB_G0294625	DDB_G0294625_ps	putative pseudogene%3B conserved Dictyostelium protein family
chr6	1607713	1608038	-	DDB_G0292526	DDB_G0292526	NA
chr6	1609068	1610390	-	DDB_G0292430	DDB_G0292430	NA
chr6	1610862	1612676	-	DDB_G0292432	DDB_G0292432	NA
chr6	1614536	1616629	+	DDB_G0295841	DDB_G0295841	NA
chr6	1616689	1617934	-	DDB_G0292528	DDB_G0292528	NA
chr6	1618538	1619731	+	DDB_G0292434	DDB_G0292434	NA
chr6	1620628	1623121	-	DDB_G0292436	triA	prespore-specific gene that regulates cell sorting and morphogenesis%3B in mutants the spore mass is suspended halfway up the stalk%3Cbr%3E %3Cb%3ENomenclature note:%3C%2Fb%3E trishanku is the king in Hindu mythology who is suspended halfway between heaven and earth 
chr6	1625548	1628836	+	DDB_G0292530	DDB_G0292530	similar to D. purpureum protein
chr6	1629116	1630501	-	DDB_G0292532	DDB_G0292532_ps	Dictyostelium family gene
chr6	1631231	1632260	+	DDB_G0292438	DDB_G0292438	NA
chr6	1632296	1633363	-	DDB_G0292440	DDB_G0292440	NA
chr6	1633774	1634050	+	DDB_G0292534	DDB_G0292534	NA
chr6	1634108	1634518	-	DDB_G0292536	DDB_G0292536_ps	putative pseudogene%3B carbohydrate%2Fpurine kinase domain-containing protein%3B similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0292440%22%3E%3Ci%3EDDB_G0292440%3C%2Fi%3E%3C%2Fa%3E
chr6	1635942	1637975	+	DDB_G0292538	gtpbp1	ortholog of the mammalian GTPBP1 and very similar to GTPBP2%3B contains a translation elongation factor EFTu%2FEF1A%2C domain 2 and C-terminal domain
chr6	1638801	1641612	-	DDB_G0292442	DDB_G0292442	phosphorylates NAD%2B to NADP%2B
chr6	1642791	1647510	-	DDB_G0292550	DDB_G0292550	NA
chr6	1649565	1650758	-	DDB_G0292378	fhbA	NA
chr6	1651520	1652908	-	DDB_G0292380	fhbB	NA
chr6	1653442	1654955	-	DDB_G0292444	DDB_G0292444	contains two SAP domains
chr6	1655640	1659548	+	DDB_G0292446	DDB_G0292446	NA
chr6	1659633	1660676	-	DDB_G0292448	DDB_G0292448	NA
chr6	1660973	1663352	+	DDB_G0292450	DDB_G0292450	NA
chr6	1664089	1664160	-	DDB_G0295447	tRNA-Cys-GCA-8	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1664228	1666387	+	DDB_G0292452	DDB_G0292452_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr6	1666854	1667990	+	DDB_G0292454	DDB_G0292454	NA
chr6	1668118	1670506	-	DDB_G0292456	apeh	enzyme cleaves an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide
chr6	1671355	1673121	+	DDB_G0292458	DDB_G0292458	NA
chr6	1673522	1674865	-	DDB_G0292382	psmC5	ATPase subunit and regulatory subcomplex of the 26S proteasome%3B developmentally regulated TAT binding protein homolog
chr6	1676096	1677186	+	DDB_G0292460	rpl6	protein component of the large (60S) ribosomal subunit%3B ribosomal protein L6 homolog
chr6	1678244	1679313	+	DDB_G0292462	DDB_G0292462	NA
chr6	1679719	1681302	+	DDB_G0292464	DDB_G0292464	homolog of human DGCR14%2C believed to play a role in velocardiofacial%2FDiGeorge syndrome (VCFS%2FDGS)
chr6	1681385	1683587	-	DDB_G0292466	nol10	ortholog of H. sapiens NOL10 and S. cerevisiae ENP2
chr6	1683880	1685955	+	DDB_G0292468	DDB_G0292468	NA
chr6	1686299	1688407	+	DDB_G0292470	anapc7	component of the anaphase-promoting complex%2Fcyclosome (APC%2FC)%2C a cell cycle-regulated ubiquitin ligase that controls progression through the cell cycle
chr6	1689735	1691662	+	DDB_G0292472	DDB_G0292472	NA
chr6	1692117	1693421	-	DDB_G0292474	DDB_G0292474	NA
chr6	1694801	1697129	+	DDB_G0292390	atg1	Dictyostelium homolog of yeast atg1%2C belongs to the ULK (Unc-51-like kinase) family of kinases%3B required for macroautophagy
chr6	1697908	1699365	+	DDB_G0292476	DDB_G0292476	similar to human PRSS16 (thymus-specific serine protease)%3B contains a putative signal peptide
chr6	1700323	1701189	-	DDB_G0292540	DDB_G0292540_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	1702357	1702674	-	DDB_G0292542	DDB_G0292542	NA
chr6	1703275	1703347	-	DDB_G0295445	tRNA-Lys-UUU-23	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1704175	1708149	+	DDB_G0292478	DDB_G0292478	NA
chr6	1708601	1710848	+	DDB_G0292480	DDB_G0292480	NA
chr6	1711273	1711824	+	DDB_G0292482	DDB_G0292482	NA
chr6	1712190	1713806	+	DDB_G0292484	DDB_G0292484	NA
chr6	1717075	1725454	+	DDB_G0292544	pks42	putative type I iterative polyketide synthase
chr6	1725966	1734352	+	DDB_G0292488	pks43_ps	putative pseudogene%3B beta-ketoacyl synthase family protein
chr6	1734904	1735743	+	DDB_G0292492	DDB_G0292492	NA
chr6	1735919	1739473	-	DDB_G0292386	carmil	NA
chr6	1739944	1743059	-	DDB_G0292494	DDB_G0292494	similar to human TTC39A and TTC39B%3B matches PFAM outer membrane protein%2C IML2%2C mitochondrial%2Ftetratricopeptide repeat protein 39
chr6	1743792	1745652	+	DDB_G0292496	cyp520A1	NA
chr6	1745775	1745927	-	DDB_G0292498	DDB_G0292498	NA
chr6	1746019	1746759	-	DDB_G0292500	DDB_G0292500	NA
chr6	1747364	1748056	+	DDB_G0292502	DDB_G0292502	NA
chr6	1748396	1752103	+	DDB_G0292504	rad17	similar to S. pombe and H. sapiens RAD17%2C and S. cerevisiae RAD24%3B component of Rad17-RFC complex%2C which loads the 9-1-1 (Rad9-Rad1-Hus1) complex onto damaged DNA
chr6	1752243	1753304	-	DDB_G0292546	DDB_G0292546	NA
chr6	1754062	1755226	+	DDB_G0292384	abcH1	consists of one ABC domain and lacks a transmembrane domain
chr6	1755318	1757612	-	DDB_G0292506	DDB_G0292506	NA
chr6	1757953	1758587	-	DDB_G0292508	aplP	NA
chr6	1758891	1758972	+	DDB_G0295311	tRNA-Ser-UGA-10	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1759374	1760057	-	DDB_G0292548	DDB_G0292548_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1761326	1761407	-	DDB_G0295443	tRNA-Ser-UGA-12	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1762213	1763550	+	DDB_G0295797	DDB_G0295797	contains a signal peptide
chr6	1763747	1764499	-	DDB_G0295799	DDB_G0295799	weakly similar to smlA
chr6	1765213	1765695	+	DDB_G0295801	DDB_G0295801	NA
chr6	1765779	1768147	-	DDB_G0295791	DDB_G0295791	NA
chr6	1769740	1774509	+	DDB_G0295683	DDB_G0295683	NA
chr6	1775198	1775683	+	DDB_G0295803	DDB_G0295803	NA
chr6	1776201	1776283	+	DDB_G0295313	tRNA-Leu-UAA-13	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1777391	1777665	+	DDB_G0292712	DDB_G0292712_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	1778529	1779572	-	DDB_G0292568	DDB_G0292568	NA
chr6	1780390	1784905	+	DDB_G0292714	DDB_G0292714	NA
chr6	1784981	1785588	-	DDB_G0292570	DDB_G0292570	NA
chr6	1786504	1788697	-	DDB_G0292554	abcB5	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr6	1789760	1790180	+	DDB_G0292572	DDB_G0292572_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0271784%22%3EDDB_G0271784%3C%2Fa%3E 
chr6	1791327	1792316	+	DDB_G0292574	DDB_G0292574	NA
chr6	1792509	1794115	-	DDB_G0292576	DDB_G0292576_ps	putative pseudogene%3B fragment%2C very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0271786%22%3EDDB_G0271786%3C%2Fa%3E
chr6	1794634	1794706	+	DDB_G0295315	tRNA-Lys-UUU-20	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1794964	1795537	-	DDB_G0292718	DDB_G0292718_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0278527%22%3EDDB_G0278527%3C%2Fa%3E%3B back to back with another pseudogene fragment for this gene on the opposite strand
chr6	1795540	1796000	+	DDB_G0292720	DDB_G0292720_ps	putative pseudogene%3B fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0278527%22%3EDDB_G0278527%3C%2Fa%3E%3B back to back with another pseudogene fragment for this gene in the opposite direction
chr6	1796405	1799806	-	DDB_G0292578	DDB_G0292578	NA
chr6	1800000	1801087	-	DDB_G0292580	DDB_G0292580_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0285087%22%3EDDB_G0285087%3C%2Fa%3E 
chr6	1801506	1801578	-	DDB_G0295441	tRNA-Asn-GUU-19	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1801613	1801945	-	DDB_G0292582	DDB_G0292582_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0289723%22%3E%3Ci%3Eabhd%3C%2Fi%3E%3C%2Fa%3E
chr6	1802425	1803401	-	DDB_G0292584	rnaseh2A	catalytic subunit of RNase HII%2C an endonuclease that specifically degrades the RNA of RNA:DNA hybrids%3B defects in H. sapiens RNASEH2A cause Aicardi-Goutieres syndrome type 4 a genetically heterogeneous autosomal recessive encephalopathy
chr6	1803595	1805049	+	DDB_G0292586	DDB_G0292586	NA
chr6	1805115	1814945	-	DDB_G0292564	iplA	required for cAMP-stimulated Ca2%2B uptake
chr6	1815723	1816671	-	DDB_G0292588	rer1	conserved protein%2C involved in the retrieval of some endoplasmic reticulum membrane proteins from the early golgi compartment%3B contains 3 predicted transmembrane domains
chr6	1817104	1819395	-	DDB_G0292590	DDB_G0292590	NA
chr6	1819608	1820776	-	DDB_G0292592	lst8	component of the TORC2 (Tor complex 2) with Tor%2C Rip3%2C and PiaA that plays a role in regulation of adenylate cyclase (ACA) and protein kinase B (PKB) activation during aggregation
chr6	1821453	1822974	+	DDB_G0292594	cyc1	ortholog of the heme-containing component of the cytochrome b-c1 complex (CYC1)%2C which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain
chr6	1823383	1823970	-	DDB_G0292596	ube2v	putative ortholog of H. sapiens UBE2V1 and S. cerevisiae MMS2
chr6	1825370	1825662	+	DDB_G0292598	DDB_G0292598	weakly similar to hssA%2F2C%2F7E family protein%3B has a similar gene structure with a N terminal 13 nt exon  
chr6	1826095	1827141	+	DDB_G0292600	mdhB	catalyzes the reaction malate %2B NAD %3C%3D%3E oxaloacetate %2B NADH%3B contains a predicted mitochondrial transit peptide
chr6	1827272	1828150	-	DDB_G0292602	DDB_G0292602	NA
chr6	1828931	1829448	+	DDB_G0292604	dduC	downregulated in the uninfected %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0277071%22%3E%3Ci%3EdupA%3C%2Fi%3E%3C%2Fa%3E mutant
chr6	1830985	1833081	+	DDB_G0292606	tmem20	putative drug%2Fmetabolite transporter%2C containing 10 predicted transmembrane domains
chr6	1833377	1833449	+	DDB_G0295317	tRNA-Asn-GUU-16	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1833713	1834839	+	DDB_G0292608	med4	ortholog of the mediator of RNA polymerase II transcription subunit 4%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr6	1834902	1835927	-	DDB_G0292722	DDB_G0292722	NA
chr6	1836361	1836431	+	DDB_G0295319	tRNA-Gly-GCC-15	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr6	1837565	1837635	-	DDB_G0295439	tRNA-Gly-GCC-18	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr6	1837996	1838066	-	DDB_G0295437	tRNA-His-GUG-10	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1838484	1839573	-	DDB_G0292610	DDB_G0292610	contains one putative transmembrane domain
chr6	1840465	1841967	+	DDB_G0292612	DDB_G0292612	NA
chr6	1842218	1842570	-	DDB_G0292614	DDB_G0292614	NA
chr6	1843458	1843778	-	DDB_G0292704	DDB_G0292704	NA
chr6	1845104	1847413	+	DDB_G0292616	DDB_G0292616	NA
chr6	1847428	1848747	-	DDB_G0292618	ogg1	similar to E. coli MutM and OGG1%2C a bifunctional DNA glycosylase that contains an activity that excises 8-oxoguanine and other derivatives of guanine from DNA and a beta-lyase activity that nicks DNA 3%27 of the lesion
chr6	1849018	1849878	+	DDB_G0292620	coq4	similar to S. cerevisiae COQ4%2C a protein of unknown function required for ubiquinone biosynthesis
chr6	1851269	1853150	+	DDB_G0292622	phdG	contains 3 PH domains
chr6	1853349	1859570	-	DDB_G0292724	taf2	TFIID subunit%2C involved in RNA polymerase II transcription initiation%2C ortholog of H. sapiens and S. cerevisiae TAF2
chr6	1860016	1862884	-	DDB_G0304683	DDB_G0304683	NA
chr6	1864394	1866302	+	DDB_G0292624	DDB_G0292624	protein serine%2Fthreonine kinase%2C CAMK group%2C CAMK1 family%3B similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases
chr6	1866598	1867916	+	DDB_G0292626	DDB_G0292626	belongs to the RAS-like GTPase superfamily%3B similar to bacterial GTP-binding protein YchF%3B similar to D. purpureum protein
chr6	1868427	1869042	+	DDB_G0292628	DDB_G0292628	NA
chr6	1869424	1869494	+	DDB_G0295321	tRNA-Pro-AGG-1	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chr6	1870453	1870535	-	DDB_G0295435	tRNA-Leu-UAA-17	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1870947	1871698	+	DDB_G0292630	DDB_G0292630	NA
chr6	1872495	1874375	+	DDB_G0292632	folC	catalyzes the reaction L-glutamate %2B H4PteGlu(n) %2B ATP %3C%3D%3E H4PteGlu(n%2B1) %2B phosphate %2B ADP%3B responsible for the addition of a polyglutamate tail to folate and folate derivatives
chr6	1874997	1875491	+	DDB_G0292634	DDB_G0292634	NA
chr6	1875598	1876080	-	DDB_G0292636	DDB_G0292636	NA
chr6	1877443	1882150	+	DDB_G0292556	DDB_G0292556	NA
chr6	1882209	1882772	-	DDB_G0292558	fam96A	conserved protein
chr6	1884330	1885070	+	DDB_G0292560	racJ	NA
chr6	1885258	1887365	-	DDB_G0292562	tgrQ1	NA
chr6	1888191	1889510	-	DDB_G0292638	DDB_G0292638	NA
chr6	1889950	1891165	+	DDB_G0292640	DDB_G0292640	NA
chr6	1891263	1892228	-	DDB_G0292566	hibA	NA
chr6	1892855	1895965	-	DDB_G0292642	DDB_G0292642	NA
chr6	1897455	1898523	+	DDB_G0292644	DDB_G0292644	NA
chr6	1898644	1899522	-	DDB_G0292646	DDB_G0292646	NA
chr6	1899844	1900755	-	DDB_G0292552	dscE	NA
chr6	1901580	1902678	+	DDB_G0292648	DDB_G0292648	has similarity to the mammalian coiled-coil domain-containing protein 12 (CCDC12)%3B the cwf18 family is involved in mRNA splicing%2C which has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe
chr6	1902913	1903686	+	DDB_G0292650	DDB_G0292650	NA
chr6	1905792	1906403	+	DDB_G0292652	DDB_G0292652	NA
chr6	1906693	1908969	+	DDB_G0292654	ndrJ	similar to class II ribonucleotide reductase%2C a monomeric form of ribonucleotide reductase that uses ribonucletide triphosphates rather than diphosphates as substrates%3B the only other eukaryote in which this enzyme is present is Euglena gracilis
chr6	1910704	1912038	-	DDB_G0292726	DDB_G0292726_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	1912886	1912956	+	DDB_G0295323	tRNA-Gly-GCC-16	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr6	1913079	1915457	-	DDB_G0292656	DDB_G0292656	NA
chr6	1915721	1916755	-	DDB_G0292658	DDB_G0292658	NA
chr6	1917310	1917759	-	DDB_G0292660	DDB_G0292660	NA
chr6	1918021	1919172	+	DDB_G0292662	DDB_G0292662	NA
chr6	1919877	1920794	+	DDB_G0292664	DDB_G0292664	contains a single calponin homology domain%3B ortholog of human transgelin-3
chr6	1920980	1922703	-	DDB_G0292666	DDB_G0292666	NA
chr6	1923247	1926739	+	DDB_G0292668	DDB_G0292668	NA
chr6	1927240	1927310	-	DDB_G0295433	tRNA-Gly-GCC-17	transfers a glycine residue to a growing polypeptide chain during protein synthesis 
chr6	1927372	1929152	-	DDB_G0292672	DDB_G0292672_ps	putative pseudogene%3B fragment%2C similar to the neighboring gene %3Ca href%3D%22%2Fgene%2FDDB_G0292674%22%3EDDB_G0292674%3C%2Fa%3E%2C and gene %3Ca href%3D%22%2Fgene%2FDDB_G0292394%22%3EDDB_G0292394%3C%2Fa%3E
chr6	1929551	1932787	-	DDB_G0292674	DDB_G0292674	NA
chr6	1933350	1937563	+	DDB_G0292676	bub1	probable mitotic checkpoint serine%2Fthreonine-protein kinase%2C a component of the mitotic checkpoint that delays anaphase until all chromosomes are properly attached to the mitotic spindle.
chr6	1937753	1938921	-	DDB_G0292678	atp12	NA
chr6	1939703	1941723	+	DDB_G0292680	DDB_G0292680	NA
chr6	1942435	1946716	+	DDB_G0292682	trappc8	conserved trafficking protein particle (TRAPP) complex subunit
chr6	1946830	1947592	-	DDB_G0292684	DDB_G0292684	NA
chr6	1948217	1948288	-	DDB_G0295431	tRNA-Met-CAU-17	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr6	1949203	1951338	+	DDB_G0292686	dus3l	ortholog of S. cerevisiae DUS3 and the animal DUS3L%3B catalyzes the synthesis of dihydrouridine%2C a modified base found in the D-loop of tRNAs
chr6	1952596	1953348	+	DDB_G0292688	commd8	belongs to a family of conserved mammalian HCaRG (hypertension-related%2C calcium-regulated gene) proteins
chr6	1953634	1954436	-	DDB_G0292690	trappc2l	conserved trafficking protein particle (TRAPP) complex subunit
chr6	1955631	1956688	+	DDB_G0292692	DDB_G0292692	NA
chr6	1956745	1959099	-	DDB_G0292694	DDB_G0292694	NA
chr6	1959495	1992916	-	DDB_G0292696	colA	collagen-binding surface protein Cna-like%2C B-type domain-containing%2C large protein
chr6	1995447	1997098	-	DDB_G0292710	DDB_G0292710	contains one PPIase cyclophilin-type domain and one RRM (RNA recognition motif) domain%3B homolog of human PPIL4 and S. pombe cyp6%3B PPIase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
chr6	1997307	1999014	-	DDB_G0292698	DDB_G0292698	weakly similar to Tra2 proteins (including human TRA2A and SFRS10) that have splicing regulatory function
chr6	1999329	2000344	-	DDB_G0292700	DDB_G0292700	NA
chr6	2001708	2002171	+	DDB_G0292728	DDB_G0292728	NA
chr6	2002272	2003159	+	DDB_G0292734	DDB_G0292734	putative eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase%3B putative protein serine%2Fthreonine kinase%3B related to the GCN2 (general control non-derepressible) family of protein kinases that phosphorylate the alpha subunit of eIF2
chr6	2003598	2004583	-	DDB_G0292730	adkB	catalyzes the reaction AMP %2B ATP %3C%3D%3E ADP %2B ADP in %3Ci%3Ede novo%3C%2Fi%3E DNA synthesis%3B predicted to be nuclear
chr6	2005101	2007934	-	DDB_G0292732	tgrF1	contains a predicted signal peptide and a putative C-terminal transmembrane domain
chr6	2009912	2012923	+	DDB_G0292772	tgrG1	NA
chr6	2013605	2014892	+	DDB_G0292774	DDB_G0292774	NA
chr6	2016449	2017075	+	DDB_G0292776	DDB_G0292776	NA
chr6	2017543	2019559	+	DDB_G0292778	ctnnbl1	ortholog of human CTNNBL1 thought to play a role in apoptosis and mRNA splicing
chr6	2019712	2021397	-	DDB_G0292780	DDB_G0292780	NA
chr6	2022556	2024374	-	DDB_G0292782	mybN	contains three Myb DNA-binding domains at the C-terminus of the predicted protein%3B similar to Dictyostelium mybB and mybC
chr6	2027082	2029262	-	DDB_G0292784	cog6	highly similar to COG6%2C component of the conserved oligomeric Golgi complex%2C which is composed of eight different subunits
chr6	2029933	2034102	+	DDB_G0292786	rad50	similar to S. cerevisiae RAD50%2C involved in processing double-strand DNA breaks with Mre11%3B in other organisms Rad50 is part of a complex with Mre11 and Nbs1%3B no Nbs1 ortholog has been found in Dictyostelium 
chr6	2034271	2037983	-	DDB_G0292788	pex6	ortholog of peroxin 6%2C required for peroxisome biogenesis%3B mutations in human homolog cause a variety of peroxisomal disorders
chr6	2038164	2039331	+	DDB_G0292770	jcdE	NA
chr6	2039368	2040946	-	DDB_G0292768	dcd1B	wealky similar to acid ceramidase%2C which catalyzes the reaction N-acylsphingoside %2B H%3Csub%3E2%3C%2Fsub%3EO %3D a carboxylate %2B sphingosine
chr6	2041426	2042289	-	DDB_G0292766	DDB_G0292766	NA
chr6	2042922	2044722	+	DDB_G0292790	cyp508D1	NA
chr6	2044931	2046783	-	DDB_G0292792	cyp508C1	NA
chr6	2047275	2049842	-	DDB_G0292794	culD	very similar to mammalian cullin 4 (CUL4A and CUL4B)%3B acts as scaffold for ubiquitin ligases (E3)%3B involved in ubiquitin-mediated protein degradation
chr6	2050588	2051160	-	DDB_G0292764	DDB_G0292764	NA
chr6	2051654	2051799	+	DDB_G0292762	hacl1_ps	putative pseudogene%3B 2-hydroxyacyl-CoA lyase (hacl) family protein
chr6	2052081	2055347	+	DDB_G0292760	lig4	ATP-dependent DNA ligase%3B contains the BRCT domain%2C which is also found in BRCA1%3B forms a complex with XRCC4
chr6	2055578	2056478	-	DDB_G0292758	mobB	similar to the Mob1 family of proteins%2C which are of unknown function but interact with Mps1 and NDR kinases%3B %3Ci%3EDictyostelium%3C%2Fi%3E MobB has been shown to bind  NdrA
chr6	2057283	2057971	+	DDB_G0292756	DDB_G0292756	NA
chr6	2058466	2058940	+	DDB_G0292754	DDB_G0292754	NA
chr6	2060204	2062690	+	DDB_G0292736	plc	catalyzes the reaction 1-phosphatidyl-1D-myo-inositol 4%2C5-bisphosphate %2B H2O %3D D-myo-inositol 1%2C4%2C5-trisphosphate %2B diacylglycero%3B regulated by the MADS-box transcription factor SrfA during development
chr6	2063367	2063981	+	DDB_G0292752	DDB_G0292752	NA
chr6	2064418	2066580	+	DDB_G0292750	DDB_G0292750	NA
chr6	2066863	2068019	-	DDB_G0292748	DDB_G0292748	NA
chr6	2069434	2072331	+	DDB_G0292746	DDB_G0292746	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity%3B also contains a PH domain involved in intracellular signaling
chr6	2072501	2074547	-	DDB_G0292744	fncL	ortholog of Fanconi anaemia complementation group L protein%2C involved DNA cross-link repair%3B null mutant is sensitive to DNA damaging agents  %3Cbr%2F%3E%3Cbr%2F%3E mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A%2C B%2C C%2C E%2C F%2C G%2C L and M%3B  the FA complex interacts with ube2t%2C a E2 ubiquitin-conjugating enzyme%2C to monoubiquitinate  FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the  FANCJ helicase as well as FANCN and FANCD1%3B in human%2C mutations in this gene cause Fanconi anaemia%2C an autosomal recessive disorder affecting all bone marrow elements%3B Dictyostelium has orthologs for %3Ca href%3D%22%2Fgene%2FDDB_G0268216%22%3EFANCD2%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0279669%22%3EFANCE%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0292744%22%3EFANCL%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0293476%22%3EFANCI%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0286621%22%3EFANCJ%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274841%22%3EFANCM%3C%2Fa%3E and   %3Ca href%3D%22%2Fgene%2FDDB_G0291199%22%3EUbe2t%3C%2Fa%3E.  
chr6	2074742	2077686	+	DDB_G0292742	DDB_G0292742	contains a dilute domain%2C found at the carboxyl terminus of non-muscle myosin V
chr6	2078010	2080742	+	DDB_G0292740	DDB_G0292740	related to H. sapiens BCSC-1 (LOH11CR2A)%2C a possible tumor suppressor gene
chr6	2081220	2082119	+	DDB_G0292738	DDB_G0292738	NA
chr6	2082530	2082611	+	DDB_G0295325	tRNA-Leu-AAG-8	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2083172	2086315	-	DDB_G0292796	DDB_G0292796_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	2086606	2087637	-	DDB_G0292798	DDB_G0292798_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	2088994	2089076	+	DDB_G0295327	tRNA-Tyr-GUA-9	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2089930	2093759	-	DDB_G0292802	DDB_G0292802	NA
chr6	2093907	2095906	-	DDB_G0295843	DDB_G0295843	contains a partial serine%2Fthreonine protein kinase catalytic domain that is similar to eukaryotic translation initiation factor 2-alpha kinase%2C however%2C the domain does not have the catalytic aspartate conserved.
chr6	2099022	2100605	+	DDB_G0292852	DDB_G0292852	ortholog of human LACE1%2C an AFG1-like ATPase%2C and similar to yeast AFG1%3B family of proteins contains a P-loop motif and are predicted to be ATPases
chr6	2100987	2102786	+	DDB_G0292822	DDB_G0292822	NA
chr6	2103859	2105652	+	DDB_G0292824	DDB_G0292824	NA
chr6	2106426	2108210	+	DDB_G0292826	DDB_G0292826	NA
chr6	2109065	2111089	+	DDB_G0292828	DDB_G0292828	NA
chr6	2111344	2113864	-	DDB_G0292830	nhe3	NA
chr6	2116342	2117495	+	DDB_G0292804	arcC	component of the Dictyostelium Arp2%2FArp3 complex
chr6	2120506	2120577	+	DDB_G0295329	tRNA-Glu-UUC-16	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	2121500	2123946	-	DDB_G0292958	mcm5	similar to MCM5%2C a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
chr6	2124835	2127096	+	DDB_G0292820	adprt2	putative ortholog of PARP2%3B catalyzes ADP-ribosylation%2C a posttranslational protein modification in which the ADP-ribose moiety of NAD is transferred onto specific amino acid side chains of cell surface%2C secreted%2C cytosolic or nuclear proteins%3B involved in single and double strand repair
chr6	2127296	2128523	-	DDB_G0292832	DDB_G0292832	NA
chr6	2129207	2130379	+	DDB_G0292960	DDB_G0292960	NA
chr6	2130562	2132271	-	DDB_G0292834	DDB_G0292834	contains an N-terminal F-box domain and six WD40 repeats
chr6	2133981	2135530	-	DDB_G0292836	DDB_G0292836	similar to minor histocompatibility antigen H13%3B belongs to the peptidase A22B family
chr6	2136060	2136513	-	DDB_G0292838	taf13	ortholog of H. sapiens TAFII18 and S. cerevisiae TAF13
chr6	2136817	2137953	+	DDB_G0292840	cysK	catalyzes the reaction O-acetyl-L-serine %2B H%3Csub%3E2%3C%2Fsub%3ES %3C%3D%3E L-cysteine %2B acetate
chr6	2138630	2139349	-	DDB_G0292842	DDB_G0292842_ps	putative pseudogene%3B very similar to %3Ca href%3D%22%2Fgene%2FDDB_G0292962%22%3EDDB_G0292962%3C%2Fa%3E
chr6	2139605	2140333	-	DDB_G0292844	DDB_G0292844	NA
chr6	2140644	2141377	-	DDB_G0292962	DDB_G0292962	NA
chr6	2142125	2143225	-	DDB_G0292964	DDB_G0292964	NA
chr6	2143669	2144906	-	DDB_G0292966	DDB_G0292966	NA
chr6	2145680	2146875	+	DDB_G0292846	DDB_G0292846	NA
chr6	2146988	2150004	-	DDB_G0292848	DDB_G0292848	NA
chr6	2151110	2153468	-	DDB_G0292968	DDB_G0292968	similar to beta-1-3%2C1-4-endoglucanase%3B expressed in pstAO cells and in upper cup during culmination
chr6	2154718	2156838	-	DDB_G0292854	DDB_G0292854	NA
chr6	2157251	2157540	-	DDB_G0292808	cspB	transcriptionally regulated by SrfA and StkA
chr6	2158048	2158308	-	DDB_G0292940	DDB_G0292940	NA
chr6	2158906	2160623	-	DDB_G0292814	symA	NA
chr6	2162983	2165971	+	DDB_G0292856	DDB_G0292856	NA
chr6	2166120	2169766	-	DDB_G0292858	DDB_G0292858	member of the patatin family of glycoproteins%2C which are storage proteins but also possess lipase activity%3B also contains 10 predicted transmembrane domains
chr6	2170773	2172234	-	DDB_G0292860	DDB_G0292860	NA
chr6	2173470	2174426	-	DDB_G0292862	ppt3	similar to mammalian PPT1%2C an enzyme which catalyzes the reaction: palmitoyl-protein %2B H%3Csub%3E2%3C%2Fsub%3EO %3D palmitate %2B protein%3B third palmitoyl-protein thioesterase in %3Ci%3EDictyostelium%3C%2Fi%3E
chr6	2176055	2176137	+	DDB_G0295331	tRNA-Tyr-GUA-10	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2176472	2176681	-	DDB_G0292970	DDB_G0292970	NA
chr6	2176999	2179826	-	DDB_G0292866	DDB_G0292866	similar to  E. coli prtB (EC  3.4.21.83) which cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues
chr6	2181555	2182295	+	DDB_G0292816	racL	NA
chr6	2182883	2183707	+	DDB_G0292818	DDB_G0292818	NA
chr6	2183910	2184633	-	DDB_G0292868	golt1	conserved protein%3B might be involved in fusion of ER-derived transport vesicles with the Golgi complex
chr6	2185175	2187115	-	DDB_G0292870	pex13	putative peroxin 13 ortholog%2C a component of the peroxisomal translocation machinery with peroxin 14 and peroxin 17%3B mutations in human homolog cause a variety of peroxisomal disorders
chr6	2188382	2190167	-	DDB_G0292872	cct4	subunit of the chaperonin CCT ring complex involved in the folding of actin and tubulin
chr6	2190855	2191532	-	DDB_G0292874	DDB_G0292874	NA
chr6	2191825	2194186	+	DDB_G0292876	DDB_G0292876	NA
chr6	2194668	2196220	+	DDB_G0292878	wshA	contains a C-terminal%2C actin-binding WH2 (Wiskott Aldrich syndrome homology region 2) domain
chr6	2196528	2200031	+	DDB_G0292972	DDB_G0292972	similar to hypothetical bacterial protein%3B contains a weak SIR2 domain
chr6	2200299	2202131	+	DDB_G0292880	DDB_G0292880	dual specificity phosphatases remove phosphate groups from tyrosine and serine%2Fthreonine residues 
chr6	2202494	2203379	-	DDB_G0292974	vti1A	NA
chr6	2204194	2208464	+	DDB_G0292812	mipA	conserved hypothetical Dictyostelium protein%3B contains a predicted signal sequence and a C-terminal transmembrane domain
chr6	2208837	2209856	-	DDB_G0292882	DDB_G0292882	NA
chr6	2211021	2213648	+	DDB_G0292884	DDB_G0292884	NA
chr6	2214235	2215853	+	DDB_G0292886	DDB_G0292886	NA
chr6	2216174	2217210	+	DDB_G0292888	DDB_G0292888	NA
chr6	2218813	2219284	+	DDB_G0292890	DDB_G0292890	NA
chr6	2219566	2220068	+	DDB_G0292892	DDB_G0292892	NA
chr6	2220707	2221813	-	DDB_G0292894	DDB_G0292894	deaminates L-ornithine to L-proline%3B this family also contains mu-crystallin%2C the major component of the eye lens in several Australian marsupials
chr6	2224445	2226237	+	DDB_G0292976	DDB_G0292976	similar to D. purpureum protein%3B contains seven predicted transmembrane domains
chr6	2228053	2229410	+	DDB_G0292946	DDB_G0292946	similar to %3Ci%3ED. purpureum%3C%2Fi%3E protein%3B contains a putative signal sequence and one central transmembrane domain
chr6	2229613	2230638	-	DDB_G0292896	eloA	fatty acid elongase with substrate specificity for monounsaturated fatty acids%2C in particular elongates 16:1%26%23916%3B9 to produce 18:1%26%23916%3B11%3B specific residues%2C such as K123 and D129 have been shown to be critical for elongase function%3B long chain fatty acids are produced at the endoplasmic reticulum membrane%3B contains at least 7 predicted transmembrane domains
chr6	2232140	2232850	+	DDB_G0292898	pgl	catalyzes the reaction 6-phospho-D-glucono-1%2C5-lactone %2B H%3Csub%3E2%3C%2Fsub%3EO %3D 6-phospho-D-gluconate
chr6	2233950	2235576	+	DDB_G0292900	DDB_G0292900	NA
chr6	2236386	2237803	+	DDB_G0292978	DDB_G0292978	conserved in Dictyostelids
chr6	2238007	2239863	-	DDB_G0292902	DDB_G0292902	the SWIM domain is found in variety of prokaryotic and eukaryotic proteins%3B it is predicted to have DNA-binding and protein-protein interaction functions in different contexts
chr6	2240229	2242819	-	DDB_G0292810	gluA	NA
chr6	2245112	2247070	-	DDB_G0292904	dync1li1	NA
chr6	2247666	2251885	-	DDB_G0292806	cluA	a 150 kD protein%2C responsible for distribution of mitochondria in the cell and cytokinesis%3B in the null mutant%2C mitochondria are clustered in the cell center
chr6	2252539	2253017	-	DDB_G0292906	DDB_G0292906	NA
chr6	2253222	2253857	+	DDB_G0292980	dph4	ortholog of the conserved DPH4 protein
chr6	2254360	2258387	+	DDB_G0292948	isw	similar to ISWI and mammalian SMARCA%2C ATPases involved in nucleosome remodeling%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr6	2258615	2258686	+	DDB_G0295333	tRNA-Cys-GCA-7	transfers a cysteine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2258753	2259076	+	DDB_G0292938	DDB_G0292938_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr6	2259430	2259651	-	DDB_G0292984	ubqN	NA
chr6	2261064	2261297	-	DDB_G0292908	ubqO	NA
chr6	2262456	2262648	-	DDB_G0292910	ubq_ps	putative pseudogene%3B fragment%3B similar to D. discoideum ubiquitin genes%2C including  %3Ca href%3D%22%2Fgene%2FDDB_G0292908%22%3E%3Ci%3EubqO%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0286907%22%3E%3Ci%3EubqD%3C%2Fi%3E%3C%2Fa%3E 
chr6	2264405	2266712	+	DDB_G0292912	psiN	contains a PA14 (anthrax protection antigen) domain and 7 Dictyostelium (CTDC) repeats%3B expressed in pstAO cells and in upper cup during culmination
chr6	2267210	2268332	+	DDB_G0292850	phlp1	NA
chr6	2269065	2269866	+	DDB_G0292914	DDB_G0292914	NA
chr6	2269986	2270312	-	DDB_G0292916	DDB_G0292916	NA
chr6	2271200	2272927	-	DDB_G0292918	DDB_G0292918	catalyzes the hydrolysis of the terminal 1%2C2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2%3B some members of this family are responsible for protein N-linked glycosylation%2C while other participate in the degradation of misfolded glycoproteins in the endoplasmic reticulum
chr6	2274050	2275614	-	DDB_G0292920	DDB_G0292920	tensin family protein (related to the tumor suppressor PTEN)%3B contains a a lipid phosphatase domain and a C2-like domain
chr6	2276495	2277021	+	DDB_G0292922	DDB_G0292922	NA
chr6	2277184	2279014	-	DDB_G0292924	adcA	contains an arrestin domain found in beta-arrestin%2C which functions in regulation of beta-adrenergic receptors%3B %3Cbr%2F%3E %3Cb%3ENomenclature conflict%3C%2Fb%3E: Do not confuse adcA (arrestin domain-containing protein) with dcd3A (alkaline dihydroceramidase)
chr6	2280235	2282724	+	DDB_G0292926	iliQ	 contains a large  ankyrin repeat region%3B induced by %3Ci%3ELegionella pneumophila%3C%2Fi%3E infection
chr6	2282811	2283293	-	DDB_G0292928	DDB_G0292928	similar to the metazoan nucleoside diphosphate kinase 6  
chr6	2283488	2285980	+	DDB_G0292930	DDB_G0292930	NA
chr6	2286132	2286204	+	DDB_G0295335	tRNA-Gln-UUG-14	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2286339	2288645	-	DDB_G0292932	DDB_G0292932	NA
chr6	2289490	2291814	-	DDB_G0292950	DDB_G0292950	conserved in Dictyostelium
chr6	2292229	2294955	-	DDB_G0292952	DDB_G0292952	NA
chr6	2295180	2295241	+	DDB_G0295633	r59	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr6	2295609	2297951	-	DDB_G0292934	DDB_G0292934	NA
chr6	2298172	2298230	+	DDB_G0295635	r60	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr6	2298272	2298337	+	DDB_G0295637	r61	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr6	2298560	2301019	-	DDB_G0292936	DDB_G0292936	NA
chr6	2301581	2302424	+	DDB_G0292954	DDB_G0292954_TE	putative DNA transposon Tdd-4%3B refer to U57081 for full-length consensus element
chr6	2303391	2305430	-	DDB_G0292990	DDB_G0292990	NA
chr6	2306939	2312234	+	DDB_G0292986	abcG10	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr6	2312391	2317424	-	DDB_G0292988	DDB_G0292988	contains seven transmembrane domains at the carboxyl terminus
chr6	2321154	2330731	+	DDB_G0293012	chdC	CHD gene family protein containing a chromodomain%2C a helicase domain%2C and a DNA-binding domain%3B chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr6	2331143	2332845	+	DDB_G0293014	DDB_G0293014	similar to human PRSS16 (thymus-specific serine protease)%3B contains a putative signal peptide
chr6	2333163	2333503	+	DDB_G0293016	DDB_G0293016	NA
chr6	2334087	2334492	-	DDB_G0293154	DDB_G0293154	this gene belongs to the trx family of genes and is located next to %3Ca href%3D%22%2Fgene%2FDDB_G0294489%22%3EtrxC%3C%2Fa%3E%3B however%2C because of sequence discrepancies (see gene model notes) it cannot be determined at this time if this might be a pseudogene or protein coding
chr6	2335005	2335723	-	DDB_G0294489	trxC	small disulphide-containing redox protein that serves as a general protein disulphide oxidoreductase%3B up-regulated at 6 hr developmental stage
chr6	2336989	2337312	+	DDB_G0293156	DDB_G0293156_ps	putative pseudogene%3B related to the TKL (tyrosine kinase-like) group of protein kinases%3B contains a partial kinase domain
chr6	2337693	2338737	+	DDB_G0293020	DDB_G0293020	NA
chr6	2340052	2340609	-	DDB_G0293158	DDB_G0293158_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	2340655	2340736	+	DDB_G0295337	tRNA-Ser-AGA-9	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2340864	2341652	+	DDB_G0293160	DDB_G0293160_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr6	2342209	2342349	-	DDB_G0293022	DDB_G0293022_ps	putative pseudogene%3B small fragment%2C similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0292240%22%3E%3Ci%3EDDB_G0292240%3C%2Fi%3E%3C%2Fa%3E
chr6	2342348	2342748	-	DDB_G0293024	colA_ps6	putative pseudogene%3B small fragment similar to the large colossin A gene %3Ca href%3D%22%2Fgene%2FDDB_G0292696%22%3E%3Ci%3EcolA%3C%2Fi%3E%3C%2Fa%3E 
chr6	2343104	2343601	-	DDB_G0293026	DDB_G0293026	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293162%22%3E%3Ci%3EDDB_G0293162%3C%2Fi%3E%3C%2Fa%3E
chr6	2344265	2344777	+	DDB_G0293028	DDB_G0293028	contains one putative coiled-coil domain and one putative transmembrane domain
chr6	2346747	2347244	-	DDB_G0293162	DDB_G0293162	highly similar to %3Ci%3E%3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293026%22%3E%3Ci%3EDDB_G0293026%3C%2Fi%3E%3C%2Fa%3E%3C%2Fi%3E
chr6	2347717	2347797	-	DDB_G0295429	tRNA-Ser-GCU-12	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2348091	2351327	-	DDB_G0293030	mileS	catalyzes the reaction ATP %2B L-isoleucine %2B tRNAIle %3D AMP %2B diphosphate %2B L-isoleucyl-tRNAIle
chr6	2351624	2356321	-	DDB_G0293032	DDB_G0293032	NA
chr6	2357058	2358689	+	DDB_G0293164	DDB_G0293164	NA
chr6	2359312	2360466	+	DDB_G0293166	DDB_G0293166	NA
chr6	2360817	2364250	-	DDB_G0293168	ddx17	conserved RNA helicase%3B very similar to mammalian DDX17 (p72) and DDX5 (p68) and yeast DBP2
chr6	2365100	2366596	+	DDB_G0293140	DDB_G0293140_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	2365116	2365187	+	DDB_G0295339	tRNA-Glu-CUC-2	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	2367392	2370667	+	DDB_G0292992	helA	NA
chr6	2371825	2373052	-	DDB_G0293034	DDB_G0293034	NA
chr6	2373448	2375541	+	DDB_G0293036	ddx5	ortholog of H. sapiens DDX5
chr6	2375925	2376414	+	DDB_G0293038	DDB_G0293038	NA
chr6	2376674	2378860	+	DDB_G0293040	DDB_G0293040	NA
chr6	2379108	2380439	-	DDB_G0293042	DDB_G0293042	NA
chr6	2381806	2383956	-	DDB_G0293044	DDB_G0293044	NA
chr6	2385585	2389568	-	DDB_G0293004	ctaA	NA
chr6	2389862	2390374	-	DDB_G0293046	DDB_G0293046	NA
chr6	2392178	2395431	+	DDB_G0293170	DDB_G0293170	NA
chr6	2395700	2397669	+	DDB_G0293008	cpnA	Ca(2%2B)-dependent phospholipid-binding protein%3B contains two C2 domains and a VWFA domain.
chr6	2398022	2398312	-	DDB_G0293048	DDB_G0293048	similar to D. purpureum protein
chr6	2399122	2399994	-	DDB_G0293050	DDB_G0293050	NA
chr6	2402071	2403845	+	DDB_G0293052	eif3E	EIF3E ortholog%2C the eukaryotic initiation factor p48 subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr6	2404735	2406126	+	DDB_G0293054	DDB_G0293054	NA
chr6	2406225	2408333	-	DDB_G0293056	DDB_G0293056	NA
chr6	2409869	2413081	+	DDB_G0293058	DDB_G0293058	NA
chr6	2413794	2414951	+	DDB_G0293060	DDB_G0293060	NA
chr6	2415200	2415445	+	DDB_G0293062	DDB_G0293062	conserved in plants and bacteria%3B predicted to have a structural domain found in several acyl-CoA acyltransferase enzymes
chr6	2415988	2417008	-	DDB_G0292998	rasB	nuclear Ras that may have a role in cell division and%2For nuclear division%3B expressed throughout growth and development
chr6	2418202	2420015	-	DDB_G0293064	DDB_G0293064	NA
chr6	2420535	2423498	-	DDB_G0293066	DDB_G0293066	conserved in Dictyostelium%3B contains one putative transmembrane domain
chr6	2425522	2426469	+	DDB_G0293068	DDB_G0293068	NA
chr6	2426564	2433958	-	DDB_G0293070	DDB_G0293070	putative ortholog of H. sapiens TEP1%2C a component of the telomerase ribonucleoprotein complex involved in replication of chromosome termini
chr6	2434758	2436649	-	DDB_G0293072	DDB_G0293072	NA
chr6	2437739	2439363	-	DDB_G0293074	DDB_G0293074	belongs to the amino acid%2Fauxin permease family%3B similar to human SLC36A4%3B disruption reduces extracellular GABA levels
chr6	2441945	2446355	+	DDB_G0293076	xpo6	ortholog of H. sapiens XPO6 involved in protein export from the nucleus
chr6	2446845	2447915	-	DDB_G0293078	DDB_G0293078	NA
chr6	2448065	2449662	-	DDB_G0293080	cyp508B2_ps	putative pseudogene%3B related to the cytochrome P450 family
chr6	2450060	2451353	-	DDB_G0293082	DDB_G0293082	NA
chr6	2452128	2458783	-	DDB_G0293084	zizB	belongs to the DOCK superfamily
chr6	2460151	2460883	+	DDB_G0293086	copZb	zeta subunit of the coatomer complex%3B involved in intracellular protein transport%3B there is another gene encoding a zeta subunit%2C %3Ca href%3D%22http:%2F%2Fdictybase.org%2Fgene%2FDDB_G0289523%22%3E %3Ci%3EcopZa%3C%2Fi%3E%3C%2Fa%3E
chr6	2461261	2462497	-	DDB_G0293088	rtnlc	endoplasmic reticulum protein of unknown function found in all eukaryotes
chr6	2463701	2469724	+	DDB_G0293090	DDB_G0293090	NA
chr6	2470132	2472773	+	DDB_G0293172	DDB_G0293172_ps	putative pseudogene%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0293174%22%3EDDB_G0293174%3C%2Fa%3E
chr6	2473465	2477486	+	DDB_G0293174	DDB_G0293174	NA
chr6	2478517	2478588	-	DDB_G0295427	tRNA-Glu-CUC-3	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	2479676	2479748	-	DDB_G0295425	tRNA-Ala-AGC-14	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2479985	2481319	+	DDB_G0293142	DDB_G0293142_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	2482983	2484317	+	DDB_G0293144	DDB_G0293144_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	2485971	2491208	+	DDB_G0293176	DDB_G0293176	NA
chr6	2491651	2493008	+	DDB_G0293098	DDB_G0293098	NA
chr6	2493284	2497275	-	DDB_G0293006	gefF	putative Ras guanine nucleotide exchange factor%3B promotes the exchange of GDP for GTP on Ras small GTPases thus converting them into the active form
chr6	2497885	2498904	-	DDB_G0293178	DDB_G0293178	NA
chr6	2499532	2500883	+	DDB_G0293180	csn6	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8) 
chr6	2501320	2506713	+	DDB_G0293002	tagA	amino terminus has a serine protease domain%2C carboxyl terminus consists of a half-transporter of the ABCB family
chr6	2506785	2507399	-	DDB_G0293100	DDB_G0293100	NA
chr6	2508062	2509321	-	DDB_G0293102	DDB_G0293102	NA
chr6	2517023	2520139	-	DDB_G0293106	DDB_G0293106	NA
chr6	2520283	2521716	-	DDB_G0293108	DDB_G0293108	NA
chr6	2522191	2525810	+	DDB_G0293110	ipo13A	ortholog of importin 13%2C also known as Ran-binding protein 13%2C a nuclear transport receptor serves as receptor for nuclear localization signals (NLS) in cargo substrates and mediates docking of the importin%2Fsubstrate complex to the nuclear pore complex
chr6	2526722	2526995	+	DDB_G0293112	DDB_G0293112	NA
chr6	2527421	2528650	-	DDB_G0293114	DDB_G0293114	NA
chr6	2529994	2530449	+	DDB_G0293116	DDB_G0293116	enriched in gametes
chr6	2530991	2531851	-	DDB_G0292996	rasD	expressed in pstAO cells and in upper cup during culmination
chr6	2533687	2535326	+	DDB_G0293182	expl8	similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B but with a divergent carboxyl terminus%3B contains a predicted signal peptide
chr6	2535539	2537077	+	DDB_G0293118	DDB_G0293118	NA
chr6	2538129	2539938	+	DDB_G0293148	expl9	similar to plant expansins%2C which modify the cell wall to allow expansion during cell growth%3B but with a divergent carboxyl terminus%3B contains a predicted signal peptide
chr6	2540484	2544382	+	DDB_G0293184	DDB_G0293184	kinase domain similar to S. pombe cdc7%2C cell division control protein 7 which plays a role in cytokinesis%3B contains RhoGAP domain found in the Rho family of small G proteins%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr6	2544546	2546079	-	DDB_G0293186	DDB_G0293186	NA
chr6	2546935	2553640	-	DDB_G0293120	DDB_G0293120	chromatin remodeling complex subunit R (CHR) protein%3B SWI2%2FSNF2 homolog
chr6	2553978	2554422	-	DDB_G0293188	DDB_G0293188	NA
chr6	2554630	2555516	-	DDB_G0293122	DDB_G0293122	similar to human GSTT2 (glutathione S-transferase theta-2)%3B glutathione transferases participate in the detoxification of reactive electrophilic compounds by catalysing their conjugation to glutathione
chr6	2556040	2556944	-	DDB_G0293000	rps3	protein component of the small (40S) ribosomal subunit
chr6	2557594	2561244	-	DDB_G0293124	kxcB	kinase domain similar to those of stress-induced STK kinases%3B contains a DH (Dbl homology) domain followed by a PH (pleckstrin homology) domain%2C found in proteins shown to encode a GEF activity specific for Rho family members
chr6	2563001	2564757	-	DDB_G0292994	pdhA	catalyzes the reaction lipoamide %2B pyruvate %3C%3D%3E S-acetyldihydrolipoamide %2B CO%3Csub%3E2%3C%2Fsub%3E%3B E1 alpha component of pyruvate dehydrogenase complex%2C which contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1%3B phdA%2C %3Ca href%3D%22 %2Fgene%2FDDB_G0276417%22%3E phdB%3C%2Fa%3E)%2C dihydrolipoamide acetyltransferase (E2%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0277847%22%3E phdC%3C%2Fa%3E) and lipoamide dehydrogenase (E3%3B %3Ca href%3D%22 %2Fgene%2FDDB_G0291648%22%3Elpd)%3C%2Fa%3E.
chr6	2565278	2566239	-	DDB_G0293126	DDB_G0293126	NA
chr6	2567187	2574265	+	DDB_G0293128	DDB_G0293128	NA
chr6	2574912	2577543	+	DDB_G0293130	clcF	CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles%3B they assemble to form homo-dimers
chr6	2577800	2580197	+	DDB_G0293132	DDB_G0293132	NA
chr6	2580338	2581644	-	DDB_G0293134	DDB_G0293134	NA
chr6	2582359	2583135	+	DDB_G0293136	pigL	NA
chr6	2583503	2584608	-	DDB_G0293190	DDB_G0293190	NA
chr6	2585552	2585877	+	DDB_G0293150	DDB_G0293150	NA
chr6	2586745	2589914	+	DDB_G0293138	DDB_G0293138	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0293138 is related (first blast hit%2C both ways) to a gene which is called src1 in budding yeast. DDB_G0293138 is threefold upregulated in vegetative cells of a Dicty strain in which the retinoblastoma-like gene rblA has been disrubpted. Many genes with roles in cell cycle progression are upregulated in this strain. The gene also shows the developmental trajectory typical of cell cycle genes (see DictyExpress) in both Dd and Dp. The Dp promoter contains an element recognized by smyd3%2C a chromatin modifier which is rblA-repressed in Dicty%2C and implicated as an oncogene in vertebrates. The Dp element (TTTCCCTCC) is close to conserved in Dd (TTTCCCTCT). All of these suggest that DDB_G0293138 is a cell cycle gene in amebae. In both Dp and Dd there is also expression in late development which is rblA-independent in Dd%2C suggesting a possible cell-cycle independent role during terminal differentiation.%3Ci%3EHarry MacWilliams%2C March 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0293138%22%3E There is more information on the wiki page%3C%2Fa%3E
chr6	2590611	2591140	+	DDB_G0293010	aplD	glucosylceramide beta-glucosidase homolog
chr6	2591529	2594655	-	DDB_G0293152	DDB_G0293152_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	2595773	2596981	-	DDB_G0293270	DDB_G0293270_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	2597197	2597279	-	DDB_G0295423	tRNA-Tyr-GUA-13	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2598517	2598588	-	DDB_G0295421	tRNA-Thr-AGU-18	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2601693	2601902	+	DDB_G0293268	DDB_G0293268	NA
chr6	2602478	2605900	-	DDB_G0293266	gxcY	NA
chr6	2607099	2609345	+	DDB_G0293264	pex14	putative ortholog of peroxin 14%3B component of the peroxisomal protein import machinery%3B mutations in human homolog cause peroxisomal disorders
chr6	2609479	2609928	-	DDB_G0293262	DDB_G0293262	contains a predicted signal peptide%3B similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0268828%22%3E%3Ci%3EDDB_G0268828%3C%2Fi%3E%3C%2Fa%3E
chr6	2610415	2610912	-	DDB_G0293260	DDB_G0293260	NA
chr6	2612161	2616005	+	DDB_G0293258	DDB_G0293258	similar to myotubularin%2C a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3%2C5)-bi-phosphate
chr6	2616152	2616428	-	DDB_G0293256	DDB_G0293256	NA
chr6	2617515	2623950	+	DDB_G0293192	DG1098	NA
chr6	2624351	2624423	-	DDB_G0295419	tRNA-Ala-AGC-13	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2624493	2624575	-	DDB_G0295417	tRNA-Leu-UAA-16	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2625762	2625834	-	DDB_G0295415	tRNA-Ala-AGC-12	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2626118	2627304	-	DDB_G0293254	eif3F	EIF3S5 ortholog%2C the eukaryotic initiation factor epsilon subunit%3B In human%2C binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA%2C is composed of at least 12 different subunits
chr6	2627689	2629954	+	DDB_G0293252	DDB_G0293252	contains 2 RRM1 domains%2C a SWAP%2FSurp domain%2C and a C-terminal ENTH%2FVHS domain%3B putative RNA splicing factor%2C similar to D. purpureum gene
chr6	2630267	2631132	-	DDB_G0293250	DDB_G0293250	contains 4 predicted transmembrane domains%3B similar to D. purpureum gene
chr6	2631684	2632667	+	DDB_G0293248	grpA	involved in the unconventional secretory pathway of acbA%2C the precurser of SDF-2 (spore differentiation factor 2)%3B ortholog of the mammalian golgi reassembly stacking protein 2 (golgi reassembly-stacking protein of 55 kDa)
chr6	2633195	2633873	-	DDB_G0293246	fxn	yeast and human orthologs regulates mitochondrial iron accumulation%3B mutations in human homolog cause  Friedrich%27s ataxia
chr6	2634996	2636470	+	DDB_G0293296	DDB_G0293296	NA
chr6	2636918	2638502	+	DDB_G0293294	DDB_G0293294	NA
chr6	2638704	2640881	+	DDB_G0293244	DDB_G0293244	NA
chr6	2642031	2643476	+	DDB_G0293242	DDB_G0293242	NA
chr6	2643748	2645364	+	DDB_G0293240	DDB_G0293240	NA
chr6	2646511	2647171	+	DDB_G0293238	tgrC_ps3	putative pseudogene%3B immunoglobulin E-set family gene
chr6	2647324	2652524	+	DDB_G0293292	DDB_G0293292	putative protein serine%2Fthreonine kinase%3B N-terminal kinase domain similar to vertebrate Nek kinases which are involved in regulation of mitosis%3B C-terminal kinase domain weakly similar to ULK (Unc-51-like kinase)
chr6	2653194	2654513	+	DDB_G0293236	DDB_G0293236	NA
chr6	2654607	2658323	-	DDB_G0293198	kif10	NA
chr6	2658870	2661389	-	DDB_G0293290	DDB_G0293290	NA
chr6	2661843	2664745	-	DDB_G0293234	DDB_G0293234	ortholog of the conserved non-catalytic N-acetyltransferase that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein that contains a Met-Glu%2C Met-Asp%2C Met-Asn%2C or Met-Met N-terminus%3B ortholog of S. cerevisiae MDM20%2C the N-terminal acetyltransferase B (NatB) complex subunit
chr6	2665263	2665490	+	DDB_G0293232	grl_ps	putative pseudogene%3B fragment%2C very similar to grl (metabotropic Glutamate Receptor-Like) genes
chr6	2665567	2670007	-	DDB_G0293288	psiQ	similar to dicA1%2C an extracellular signaling molecule%2C and ecmB%2C an extracellular matrix protein%3B contains a signal peptide%2C a PA14 (anthrax protection antigen) domain%2C and 14 Dictyostelium (CTDC) repeats%3B significantly longer than other family members
chr6	2670579	2675350	-	DDB_G0293286	psiR	similar to dicA1%2C an extracellular signaling molecule%2C and ecmB%2C an extracellular matrix protein%3B expressed in prespore cells
chr6	2676069	2676278	+	DDB_G0293230	cdc26	cdc26 ortholog%3B missing about half of the carboxyl terminus
chr6	2676500	2678038	-	DDB_G0293228	gtf2h4	ortholog of S. cerevisiae TFB2%2C subunit of TFIIH and nucleotide excision repair factor 3 complexes%2C involved in transcription initiation%2C required for nucleotide excision repair
chr6	2678243	2679944	-	DDB_G0293226	rvb1	similar to S. cerevisiae RVB1%2C a component of chromatin remodeling complexes
chr6	2680686	2682211	+	DDB_G0293224	ost1	subunit of the oligosaccharyltransferase complex%2C which catalyzes asparagine-linked glycosylation of newly synthesized proteins in the ER lumen%3B ortholog of S. cerevisiae OST1 and human ribophorin I%3B contains one C-terminal transmembrane domain and an N-terminal signal peptide
chr6	2682288	2683332	-	DDB_G0293222	DDB_G0293222	NA
chr6	2684279	2685723	+	DDB_G0293220	gpn1	highly similar to vertebrate GPN1 and yeast NPA3 (Nucleolar Preribosomal Associated)
chr6	2686279	2688810	+	DDB_G0293218	vps35	ortholog of VPS35%2C a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport
chr6	2689035	2692703	-	DDB_G0293216	DDB_G0293216	NA
chr6	2694152	2696012	+	DDB_G0293214	orcE	DNA replication initiation is driven by a conserved six protein complex%2C the origin recognition complex (ORC)%3B has a role in both chromosomal replication and mating type transcriptional silencing
chr6	2696303	2698843	+	DDB_G0293212	DDB_G0293212	NA
chr6	2698963	2700051	-	DDB_G0293284	DDB_G0293284	NA
chr6	2700382	2700608	-	DDB_G0293278	DDB_G0293278	NA
chr6	2701490	2703823	-	DDB_G0293276	DDB_G0293276	member of the AGC kinase group%3B similar to kinase domains of Akt%2FPKB and MAST (microtubule-associated serine%2Fthreonine kinase) family members
chr6	2705921	2707141	-	DDB_G0293196	pcp	belongs to the paracaspase family of caspase-like cysteine proteases%3B unlike its mammalian orthologs%2C the %3Ci%3E Dictyostelium%3C%2Fi%3E protein does not have an effect on apoptosis%3B associates with the contractile vacuole membrane%3B GFP-Pcp overexpressing cells are susceptible to osmotic stress
chr6	2708230	2710258	+	DDB_G0293210	sgmB	hydrolyze the phosphodiester bond in sphingomyelin to form ceramide
chr6	2710326	2710896	-	DDB_G0293208	DDB_G0293208	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0287403%22%3E%3Ci%3EDDB_G0287403%3C%2Fi%3E%3C%2Fa%3E
chr6	2712310	2715052	+	DDB_G0293194	abcD2	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr6	2715182	2715730	-	DDB_G0293206	DDB_G0293206	NA
chr6	2716007	2718751	-	DDB_G0293204	DDB_G0293204	one of three paralogs in %3Ci%3EDictyostelium%3C%2Fi%3E (other genes: %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0283989%22%3E%3Ci%3EDDB_G0283989%3C%2Fi%3E%3C%2Fa%3E) that are putative hydrolases
chr6	2718912	2720315	-	DDB_G0293202	DDB_G0293202	has similarity to mammalian TNF receptor-associated factors 5 and 6 (TRAF5%2C TRAF6)
chr6	2721106	2722728	-	DDB_G0293274	DDB_G0293274	contains 2 FNIP domains%3B contains 1 B-box zinc finger domain
chr6	2723111	2725479	-	DDB_G0293282	DDB_G0293282_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0286677%22%3EDDB_G0286677%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0274177%22%3EDDB_G0274177%3C%2Fa%3E
chr6	2726875	2728209	-	DDB_G0293272	DDB_G0293272_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	2728442	2728523	+	DDB_G0295341	tRNA-Leu-AAG-9	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2729012	2729972	+	DDB_G0293200	DDB_G0293200_ps	putative pseudogene%3B similar to D. discoideum genes %3Ca href%3D%22%2Fgene%2FDDB_G0293836%22%3EDDB_G0293836%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0279497%22%3EDDB_G0279497%3C%2Fa%3E
chr6	2730062	2730133	-	DDB_G0295413	tRNA-Glu-UUC-20	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	2730183	2730868	+	DDB_G0293280	DDB_G0293280_RTE	part of ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-C%3B refer to GenBank AF298210 (DDB_G0293280) for a partially assembled consensus element
chr6	2733345	2736998	+	DDB_G0293300	DDB_G0293300	NA
chr6	2737579	2739659	+	DDB_G0293302	DDB_G0293302	NA
chr6	2739726	2740511	-	DDB_G0293304	DDB_G0293304	NA
chr6	2741328	2742563	+	DDB_G0293306	uba5	NA
chr6	2743223	2746940	+	DDB_G0293308	DDB_G0293308	NA
chr6	2747762	2747941	-	DDB_G0293310	DDB_G0293310	NA
chr6	2748675	2749012	+	DDB_G0293312	DDB_G0293312	NA
chr6	2749397	2749774	-	DDB_G0293314	DDB_G0293314	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr6	2750083	2750421	+	DDB_G0293316	DDB_G0293316	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr6	2750911	2751252	-	DDB_G0293318	DDB_G0293318	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr6	2751543	2751860	+	DDB_G0293320	DDB_G0293320	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon  
chr6	2752374	2752727	-	DDB_G0293322	DDB_G0293322	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon 
chr6	2753047	2753388	+	DDB_G0293336	DDB_G0293336	weakly similar to hssA%2F2C%2F7E family proteins%3B has a similar gene structure with a N terminal 13 nt exon  
chr6	2754113	2755156	+	DDB_G0293338	gxcY_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0293266%22%3E%3Ci%3EgxcY%3C%2Fi%3E%3C%2Fa%3E
chr6	2755452	2755661	-	DDB_G0293324	DDB_G0293324	NA
chr6	2756536	2756811	-	DDB_G0293326	DDB_G0293326	NA
chr6	2757100	2759103	-	DDB_G0293340	gxcKK	NA
chr6	2760211	2760718	+	DDB_G0293328	DDB_G0293328	NA
chr6	2761673	2763912	+	DDB_G0293298	mhsp70	NA
chr6	2764080	2764481	-	DDB_G0293330	DDB_G0293330	similar to bacterial prolyl endopeptidases
chr6	2765016	2765714	+	DDB_G0293332	DDB_G0293332	NA
chr6	2765769	2767301	-	DDB_G0293334	DDB_G0293334	NA
chr6	2768404	2768477	+	DDB_G0295343	tRNA-Val-UAC-7	transfers a valine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2768512	2769195	-	DDB_G0293342	DDB_G0293342_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	2770337	2770427	-	DDB_G0295411	tRNA-Ile-UAU-4	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2771961	2772051	-	DDB_G0295409	tRNA-Ile-UAU-3	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2772108	2772527	+	DDB_G0293344	DDB_G0293344_RTE	Part of ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-C%3B refer to GenBank AF298210 for partially assembled consensus element
chr6	2774066	2777149	+	DDB_G0293346	DDB_G0293346	NA
chr6	2777486	2777557	+	DDB_G0295345	tRNA-Asp-GUC-21	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	2777877	2778545	+	DDB_G0293348	DDB_G0293348_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr6	2778739	2782182	+	DDB_G0293350	DDB_G0293350_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr6	2782815	2783030	+	DDB_G0293352	DDB_G0293352_ps	putative pseudogene%3B fragment%2C similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0279873%22%3EDDB_G0279873%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0279891%22%3EDDB_G0279891%3C%2Fa%3E
chr6	2784596	2784668	+	DDB_G0295347	tRNA-Ile-AAU-13	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2784930	2785916	-	DDB_G0293354	DDB_G0293354	catalyzes the reaction (3S)-3-hydroxyacyl-CoA %3C%3D%3E trans-2(or 3)-enoyl-CoA %2B H%3Csub%3E2%3C%2Fsub%3EO
chr6	2786412	2786790	-	DDB_G0293356	DDB_G0293356	highly similar to other short proteins expressed in the prestalk region%3B expressed in pstO cells
chr6	2787551	2787944	-	DDB_G0293358	hssB	NA
chr6	2789218	2789589	+	DDB_G0293360	hssA	multicopy suppressor of %3Ci%3EdstA%3C%2Fi%3E%3B expressed in pstAO cells%3B highly similar to other short proteins expressed in the prestalk region
chr6	2790501	2790895	+	DDB_G0293362	DDB_G0293362	NA
chr6	2791219	2791695	+	DDB_G0293382	DDB_G0293382	identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293410%22%3E%3Ci%3EDDB_G0293410%3C%2Fi%3E%3C%2Fa%3E%3B similar to S. cerevisiae MIC17 (mitochondrial intermembrane space cysteine motif-containing protein)%3B contains a predicted mitochondrial transit peptide
chr6	2792033	2794197	-	DDB_G0293386	DDB_G0293386	NA
chr6	2795992	2796907	+	DDB_G0293366	DDB_G0293366	similar to bacterial cell wall-associated hydrolases
chr6	2797121	2797396	-	DDB_G0293368	act24_ps	putative pseudogene%3B contains an incomplete actin domain%3B similar to %3Ca href%3D%22%2Fgene%2FDDB_G0289505%22%3E%3Ci%3Eact24%3C%2Fi%3E%3C%2Fa%3E 
chr6	2797816	2798133	+	DDB_G0293370	DDB_G0293370	NA
chr6	2798298	2800696	-	DDB_G0293388	DDB_G0293388	putative ATP-dependent metalloprotease FtsH%2C similar to S. cerevisiae YME1%2C that plays a role in mitochondrial protein metabolism
chr6	2801637	2804362	-	DDB_G0293372	ttc27	NA
chr6	2804871	2805532	-	DDB_G0293374	dut	catalyses the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B dUTP %3C%3D%3E pyrophosphate %2B dUMP in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine deoxyribonucleotides
chr6	2805934	2817834	-	DDB_G0293376	cpras2	contains a circularly permuted GTPase domain with the conserved motifs G1-G2 lying downstream of the G3-G4-G5 motifs%3B large protein of unknown function whose domain composition is not conserved%3B a closely related ortholog is found in %3Ci%3ED. purpureum %3C%2Fi%3E
chr6	2818966	2821148	+	DDB_G0293378	DDB_G0293378	NA
chr6	2822106	2824254	+	DDB_G0293364	sigB	developmentally regulated gene whose expression is dependent on the transcription factors srfA and StkA
chr6	2824551	2826236	+	DDB_G0293380	DDB_G0293380	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB G0293380 contains a conserved domain which is best matched by COG0116%2C N6 adenine-specific DNA methylase (E-value 5e-14). The similarity to PRK11783%2C rRNA methyltransferase%2C is lower (9e-11). The blast matches list both putative RNA methylases and putative N6 adenine-specific DNA methylases. Thus%2C although it does not now appear to be possible to assign DDB_G0293380 conclusively to either category%2C the case for a DNA methylase currently looks a bit stronger.%3Cbr%3E DDB_G0293380 is overexpressed fivefold (p%3C0.008) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted. Most genes with functions necessary for cell cycle progression are overexpressed in this strain%2C and most of the overexpressed genes have identifiable cell cycle functions. A tempting interpretation is that the product of DDB_G0293380 is involved in a DNA methylation pathway which is coupled with DNA replication. %3Ci%3EHarry MacWilliams%2C December 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0293380%22%3E There is more information on the wiki page%3C%2Fa%3E
chr6	2826651	2827580	+	DDB_G0293384	DDB_G0293384	NA
chr6	2828734	2830125	+	DDB_G0293390	DDB_G0293390	NA
chr6	2830538	2831647	+	DDB_G0293392	DDB_G0293392	conserved protein%3B mammalian orthologs are predicted Zn-dependent hydrolases of the beta-lactamase fold
chr6	2831683	2832890	-	DDB_G0293394	pter	conserved phosphotriesterase family protein
chr6	2833626	2836198	+	DDB_G0293396	gxcO	NA
chr6	2836863	2836944	+	DDB_G0295349	tRNA-Leu-AAG-10	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2839313	2839873	-	DDB_G0293400	DDB_G0293400_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	2840202	2840274	+	DDB_G0295351	tRNA-Met-CAU-16	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2840392	2840462	+	DDB_G0295353	tRNA-His-GUG-8	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2841033	2842064	-	DDB_G0293402	DDB_G0293402	NA
chr6	2842898	2843374	-	DDB_G0293410	DDB_G0293410	identical to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0293382%22%3E%3Ci%3EDDB_G0293382%3C%2Fi%3E%3C%2Fa%3E%3B similar to S. cerevisiae MIC17 (mitochondrial intermembrane space cysteine motif-containing protein)%3B contains a predicted mitochondrial transit peptide
chr6	2844115	2846244	+	DDB_G0293412	DDB_G0293412	NA
chr6	2846362	2847142	-	DDB_G0293404	DDB_G0293404	poorly characterized but highly conserved protein%3B may function as a tRNA m5C methyltransferase chaperone
chr6	2847823	2852673	+	DDB_G0293414	DDB_G0293414	NA
chr6	2852833	2856482	-	DDB_G0293406	DDB_G0293406	NA
chr6	2856788	2858954	+	DDB_G0295793	DDB_G0295793	NA
chr6	2859059	2859253	+	DDB_G0293418	DDB_G0293418	NA
chr6	2859525	2861062	+	DDB_G0293420	DDB_G0293420	NA
chr6	2861187	2863916	-	DDB_G0293416	abcB1	half transporter%2C consisting of one ABC domain and one transmembrane domain
chr6	2864640	2865464	-	DDB_G0293428	DDB_G0293428	NA
chr6	2865868	2866077	-	DDB_G0293422	DDB_G0293422	NA
chr6	2868585	2868851	+	DDB_G0293424	DDB_G0293424	NA
chr6	2868959	2870651	-	DDB_G0293426	DDB_G0293426	NA
chr6	2872733	2872891	+	DDB_G0293430	DDB_G0293430	NA
chr6	2873447	2873926	-	DDB_G0293432	DDB_G0293432_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr6	2875111	2877067	-	DDB_G0293448	DDB_G0293448	NA
chr6	2877682	2878372	-	DDB_G0293434	rasG	maximally expressed during growth%3B activated by rasGEF GefR%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Gene expression is greatly perturbed in vegetative rasC-%2FrasG- double null mutants%2C and in early development a subset of important signalling genes are not induced adequately. Notable among these early genes are acaA%2C dagA%2C erkA%2C erkB%2C gpaB%2C and csbA. The discoidin I genes are also underexpresed. The expression of most of these genes (not the discoidins) is rescued when carA is overexpressed in the double null line. Most remarkably%2C the overall profile of gene expression changes in vegetative double null mutants compared to the parent strain is highly similar to that of wild-type cells six hours after infection with Legionella pneumophila compared to uninfected cells (correlation coefficient %3D 0.61) (Li et al%2C 2009)%2C making this strain partially phenocopy the Legionella-resistant dupA mutant (in terms of gene expression changes%3B correlation coefficient %3D 0.49). Of 55 genes overexpressed at least 4-fold in the vegetative rasC-%2FrasG- double mutant%2C 53 are at least 2-fold induced six hours after Legionella infection in wild-type AX4 cells (including tirA)%3B 37 of these 55 are overexpressed in uninfected dupA mutants. Further%2C 44 of the 55 overexpressed genes are developmentally induced in parental cells%2C and 22 of the 55 show significantly reduced expression upon carA overexpression in vegetative cells. %3Ci%3EGareth Bloomfield%2C November 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FrasG%22%3E There is more information on the wiki page%3C%2Fa%3E
chr6	2880255	2885774	+	DDB_G0293436	abcA3	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr6	2886461	2891055	+	DDB_G0293446	DDB_G0293446_ps	putative pseudogene%3B similar to a family of D. discoideum genes%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0290037%22%3EDDB_G0290037%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0290063%22%3EDDB_G0290063%3C%2Fa%3E
chr6	2891271	2895850	-	DDB_G0293438	abcB2	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr6	2897244	2898395	-	DDB_G0293440	DDB_G0293440	NA
chr6	2899455	2900754	-	DDB_G0293442	DDB_G0293442	NA
chr6	2901323	2903242	-	DDB_G0293444	DDB_G0293444	NA
chr6	2904523	2905177	-	DDB_G0293452	DDB_G0293452_TE	AT-rich low copy repetitive element which is thought to have no protein-coding capacity
chr6	2905541	2906050	-	DDB_G0293454	DDB_G0293454	NA
chr6	2906126	2907583	-	DDB_G0293464	DDB_G0293464	NA
chr6	2907748	2909125	+	DDB_G0293456	DDB_G0293456	NA
chr6	2911255	2915823	+	DDB_G0293450	abcG9	full transporter%2C consisting of two ABC domains and two transmembrane domains
chr6	2916261	2916733	+	DDB_G0293466	abcG_ps2	putative pseudogene%3B fragment%3B similar to abcG family proteins%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0269208%22%3E%3Ci%3EabcG19%3C%2Fi%3E%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0269206%22%3E%3Ci%3EabcG21%3C%2Fi%3E%3C%2Fa%3E
chr6	2917476	2917676	+	DDB_G0293458	gflC_ps	putative pseudogene%3B fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0270880%22%3E%3Ci%3EgflC%3C%2Fi%3E%3C%2Fa%3E 
chr6	2919081	2920452	+	DDB_G0293460	DDB_G0293460	NA
chr6	2920900	2922589	+	DDB_G0293462	cirh1a	component of the small subunit (SSU) processome containing the U3 snoRNA involved in processing of pre-18S rRNA
chr6	2922718	2926550	-	DDB_G0293468	mybS	contains one Myb DNA-binding domain 
chr6	2927015	2927823	+	DDB_G0293474	DDB_G0293474	NA
chr6	2928133	2932557	-	DDB_G0293470	cbfB	similar to %3Ci%3EDictyostelium%3C%2Fi%3E cbfA%3B contains a jmjC domain
chr6	2933475	2934662	-	DDB_G0293482	DDB_G0293482_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr6	2934812	2935687	-	DDB_G0293486	DDB_G0293486_RTE	partial ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr6	2936034	2936106	-	DDB_G0295407	tRNA-Ile-AAU-16	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2936457	2941811	+	DDB_G0293476	fncI	ortholog of Fanconi anaemia complementation group I protein%2C involved DNA cross-link repair%3B null mutant is sensitive to DNA damaging agents  %3Cbr%2F%3E%3Cbr%2F%3E  mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A%2C B%2C C%2C E%2C F%2C G%2C L and M%3B  the FA complex interacts with ube2t%2C a E2 ubiquitin-conjugating enzyme%2C to monoubiquitinate  FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the  FANCJ helicase as well as FANCN and FANCD1%3B in human%2C mutations in this gene cause Fanconi anaemia%2C an autosomal recessive disorder affecting all bone marrow elements%3B Dictyostelium has orthologs for %3Ca href%3D%22%2Fgene%2FDDB_G0268216%22%3EFANCD2%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0279669%22%3EFANCE%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0292744%22%3EFANCL%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0293476%22%3EFANCI%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0286621%22%3EFANCJ%3C%2Fa%3E%2C  %3Ca href%3D%22%2Fgene%2FDDB_G0274841%22%3EFANCM%3C%2Fa%3E and   %3Ca href%3D%22%2Fgene%2FDDB_G0291199%22%3EUbe2t%3C%2Fa%3E.  
chr6	2942975	2944498	-	DDB_G0293478	DDB_G0293478	weakly similar to cudA%3B contains the motifs believed to be required for DNA binding: LSS and RCVSK (RVVSK in CudA)
chr6	2945490	2945935	+	DDB_G0293480	DDB_G0293480	NA
chr6	2946443	2946748	-	DDB_G0293484	psenen	component of the gamma-secretase complex%2C which executes the intramembrane proteolysis of type I integral membrane proteins such as Notch
chr6	2946961	2947689	+	DDB_G0293488	DDB_G0293488	NA
chr6	2948897	2950671	+	DDB_G0293490	DDB_G0293490_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	2951996	2953178	+	DDB_G0293492	DDB_G0293492	glycoside hydrolase family 25 (GH25) comprises enzymes with lysozyme (EC:3.2.1.17) activity%3B contains a putative N-terminal signal peptide
chr6	2954533	2954605	-	DDB_G0295405	tRNA-Lys-CUU-10	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2956996	2957068	-	DDB_G0295403	tRNA-Lys-CUU-9	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2959996	2960781	-	DDB_G0293494	DDB_G0293494	NA
chr6	2961150	2963780	-	DDB_G0293496	vps52B	similar to S. cerevisiae VPS52%2C component of the GARP (Golgi-associated retrograde protein) complex
chr6	2964407	2965754	+	DDB_G0293498	DDB_G0293498	contains a UBX domain%2C found in ubiquitin-regulatory proteins
chr6	2965853	2967115	-	DDB_G0293500	DDB_G0293500	NA
chr6	2967908	2968721	+	DDB_G0293502	rpl23a	protein component of the large (60S) ribosomal subunit
chr6	2968920	2970687	-	DDB_G0293504	DDB_G0293504	belongs to the nucleotidyltransferase superfamily%3B contains one poly A polymerase head domain
chr6	2971375	2971509	-	DDB_G0293506	DDB_G0293506_ps	putative pseudogene%3B small fragment%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0281763%22%3EDDB_G0281763%3C%2Fa%3E 
chr6	2972530	2975733	+	DDB_G0293508	DDB_G0293508	NA
chr6	2976341	2978017	+	DDB_G0293510	gacV	weakly similar to HNRNP family (heterogeneous nuclear ribonucleoprotein)
chr6	2978200	2979726	-	DDB_G0293512	DDB_G0293512	NA
chr6	2980192	2980555	+	DDB_G0293518	DDB_G0293518_ps	putative pseudogene%3B similar to a D. discoideum gene family%2C including %3Ca href%3D%22%2Fgene%2FDDB_G0295813%22%3EDDB_G0295813%3C%2Fa%3E
chr6	2981805	2984324	+	DDB_G0293520	exoc3	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr6	2984590	2985081	+	DDB_G0293514	DDB_G0293514	NA
chr6	2985396	2985468	+	DDB_G0295355	tRNA-Lys-CUU-8	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr6	2985588	2986136	+	DDB_G0293516	DDB_G0293516_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	2988655	2989405	+	DDB_G0293530	pefB	similar to mammalian apoptosis component ALG-2%3B contains 5 EF-hand calcium binding domains
chr6	2989503	2990542	-	DDB_G0293542	DDB_G0293542	NA
chr6	2990987	2997466	-	DDB_G0293544	cepK	localizes to the corona of the centrosome and to centromeres%3B affects cell growth and chemotactic motility and is involved in the interaction with the nuclear envelope
chr6	2998070	2998890	+	DDB_G0293694	DDB_G0293694	NA
chr6	3000314	3001296	+	DDB_G0293526	racC	NA
chr6	3002117	3005542	+	DDB_G0293534	DDB_G0293534	NA
chr6	3006120	3006433	+	DDB_G0293696	DDB_G0293696	small Dictyostelium protein family%3B absent from other organisms%3B very similar to neighboring gene %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0293698%22%3E%3Ci%3EDDB_G0293698%3C%2Fi%3E%3C%2Fa%3E
chr6	3007121	3007427	+	DDB_G0293698	DDB_G0293698	small Dictyostelium protein family%3B absent from other organisms%3B very similar to neighboring gene %3Ca href%3D%22gene_page.pl?primary_id%3DDDB_G0293696%22%3E%3Ci%3EDDB_G0293696%3C%2Fi%3E%3C%2Fa%3E
chr6	3008610	3008681	-	DDB_G0295401	tRNA-Asp-GUC-22	transfers an aspartic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	3009712	3011046	+	DDB_G0293692	DDB_G0293692_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	3013335	3014141	-	DDB_G0293700	rps21	protein component of the small (40S) ribosomal subunit%3B ribosomal protein S21 homolog
chr6	3014705	3015924	-	DDB_G0293702	rfc3	ortholog of %3Ci%3EH. sapiens%3C%2Fi%3E RFC3 (38 kDa subunit) and %3Ci%3ES. cerevisiae%3C%2Fi%3E RFC5
chr6	3016431	3018565	+	DDB_G0293546	mre11	similar to S. cerevisiae MRE11%2C involved in processing double-strand DNA breaks with Rad50%3B in other organisms Mre11 is part of a complex with Rad50 and Nbs1%3B no Nbs1 ortholog has been found in Dictyostelium 
chr6	3018651	3020648	-	DDB_G0293548	DDB_G0293548	NA
chr6	3021203	3022245	+	DDB_G0293540	empB	NA
chr6	3022571	3026227	+	DDB_G0293550	DDB_G0293550	NA
chr6	3026375	3028618	-	DDB_G0293552	DDB_G0293552	NA
chr6	3029753	3032914	-	DDB_G0293524	ppk1	similar to bacterial PPK (PPK1 family)%2C which synthesizes poly P%2C a polymer of up to hundreds of phosphate residues
chr6	3034210	3035128	-	DDB_G0293704	DDB_G0293704	conserved small seven transmembrane-containing domain protein
chr6	3035802	3037515	+	DDB_G0293554	sf1	ortholog of the conserved splicing factor 1%3B binds to the intron branch point sequence (BPS) of the pre-mRNA%3B necessary for the ATP-dependent first step of spliceosome assembly
chr6	3038260	3039219	-	DDB_G0293706	mobC	similar to the Mob1 family of proteins%2C which are of unknown function but interact with Mps1 and NDR kinases
chr6	3039817	3040946	-	DDB_G0293556	mcfG	ortholog of slc25a20%2C involved in transport of carnitine%2Facylcarnitine across the mitochondrial membrane%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr6	3041877	3044187	+	DDB_G0293558	pabpc1A	similar to mammalian PABPC1%3B involved in cytoplasmic regulatory processes of mRNA metabolism%2C binding the poly(A) tail of mRNA
chr6	3044865	3048492	-	DDB_G0293560	rpa2	component of the RNA polymerase I complex%3B ortholog of S. cerevisiae RPA135
chr6	3048907	3050490	+	DDB_G0293562	DDB_G0293562	NA
chr6	3050595	3051372	-	DDB_G0293564	gins2	subunit 2 of the conserved replication complex GINS%2C which is essential for initiation of DNA replication in X. laevis
chr6	3051866	3052770	+	DDB_G0293566	DDB_G0293566	glycoside hydrolase family 25 (GH25) comprises enzymes with lysozyme (EC:3.2.1.17) activity%3B contains a putative N-terminal signal peptide
chr6	3053148	3053219	+	DDB_G0295357	tRNA-Glu-UUC-17	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	3054649	3055489	+	DDB_G0293708	DDB_G0293708	NA
chr6	3056692	3060850	+	DDB_G0293570	DDB_G0293570	contains a RUN domain%2C which is predicted to play a role in Ras-like GTPase signaling pathways
chr6	3061098	3062071	-	DDB_G0293572	DDB_G0293572	NA
chr6	3063340	3063668	+	DDB_G0293574	DDB_G0293574	NA
chr6	3063826	3064716	-	DDB_G0293576	esf2	ortholog of mammalian ABT1
chr6	3066410	3067744	-	DDB_G0293684	DDB_G0293684_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	3068583	3068665	+	DDB_G0295359	tRNA-Tyr-GUA-11	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3069439	3069510	-	DDB_G0295399	tRNA-Glu-UUC-19	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	3070057	3072584	-	DDB_G0293578	DDB_G0293578	NA
chr6	3073231	3074015	-	DDB_G0293580	DDB_G0293580	catalyzes the reaction H%3Csub%3E2%3C%2Fsub%3EO %2B dCTP %3C%3D%3E NH3 %2B dUTP in %3Ci%3Ede novo%3C%2Fi%3E biosynthesis of pyrimidine deoxyribonucleotides
chr6	3074914	3075657	+	DDB_G0293582	DDB_G0293582	NA
chr6	3076225	3078120	+	DDB_G0293584	sqle	catalyzes the reaction squalene %2B AH2 %2B O2 %3D (S)-squalene-2%2C3-epoxide %2B A %2B H2O%3B catalyzes the first oxygenation step in sterol biosynthesis
chr6	3080260	3080990	+	DDB_G0293712	DDB_G0293712	NA
chr6	3081583	3087627	-	DDB_G0293586	DDB_G0293586	contains one LisH domain%3B contains 3 predicted coiled-coil domains
chr6	3091013	3093686	+	DDB_G0293538	dcd2A	ceramidase bearing more similarity with neural and alkaline ceramidases%3B however pH optimum of the enzyme is 3
chr6	3093908	3095110	-	DDB_G0293588	ggps1	ortholog of the mammalian geranylgeranyl diphosphate synthase 1%3B includes the enzymes dimethylallyltransferase (EC 2.5.1.1)%2C geranyltranstransferase (EC 2.5.1.10)%2C and farnesyltranstransferase  (EC 2.5.1.29)
chr6	3095576	3100096	-	DDB_G0293590	DDB_G0293590	NA
chr6	3100713	3101281	+	DDB_G0293592	DDB_G0293592	NA
chr6	3101875	3102486	+	DDB_G0293594	DDB_G0293594	NA
chr6	3102749	3103376	+	DDB_G0293714	DDB_G0293714	NA
chr6	3103876	3104664	+	DDB_G0293716	DDB_G0293716_ps	putative pseudogene%3B similar to D. discoideum gene %3Ca href%3D%22%2Fgene%2FDDB_G0293836%22%3EDDB_G0293836%3C%2Fa%3E
chr6	3104858	3105434	+	DDB_G0293718	DDB_G0293718	NA
chr6	3106575	3109048	+	DDB_G0293596	DDB_G0293596	NA
chr6	3109284	3111290	-	DDB_G0293598	DDB_G0293598	NA
chr6	3111920	3113253	-	DDB_G0293600	DDB_G0293600_ps	putative pseudogene%3B fragment%2C similar to the neighboring genes %3Ca href%3D%22%2Fgene%2FDDB_G0293720%22%3EDDB_G0293720%3C%2Fa%3E%2C %3Ca href%3D%22%2Fgene%2FDDB_G0293722%22%3EDDB_G0293722%3C%2Fa%3E
chr6	3113521	3118191	-	DDB_G0293720	DDB_G0293720	NA
chr6	3118866	3123504	-	DDB_G0293722	DDB_G0293722	NA
chr6	3124039	3126293	-	DDB_G0293724	DDB_G0293724	conserved hypothetical 695 aa Dictyostelium protein
chr6	3126896	3127907	-	DDB_G0293604	DDB_G0293604	similar to retinol dehydrogenase
chr6	3128846	3129901	-	DDB_G0293606	DDB_G0293606	some members of this family have guanine nucleotide exchange activity
chr6	3130386	3131704	+	DDB_G0293608	wdr53	NA
chr6	3132339	3132411	+	DDB_G0295361	tRNA-Ala-AGC-11	transfers an alanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3133176	3133337	+	DDB_G0293688	DDB_G0293688	NA
chr6	3133759	3133831	+	DDB_G0295363	tRNA-Ile-AAU-14	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3135284	3136807	+	DDB_G0293610	DDB_G0293610	conserved protein in ciliates and plants%3B contains 9 predicted transmembrane domains%2C including one signal peptide%3B there is an almost identical D. discoideum protein%2C %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3D DDB_G0283707%22%3E%3Ci%3E DDB_G0283707 %3C%2Fi%3E%3C%2Fa%3E
chr6	3137397	3137469	-	DDB_G0295397	tRNA-Lys-UUU-22	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3138091	3139425	+	DDB_G0293690	DDB_G0293690_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	3139824	3140024	+	DDB_G0293726	DDB_G0293726_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	3141444	3141516	+	DDB_G0295365	tRNA-Lys-UUU-21	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3141895	3144669	+	DDB_G0293612	DDB_G0293612	NA
chr6	3144728	3147821	-	DDB_G0293614	DDB_G0293614	ortholog of S. cerevisiae DIS3 and H. sapiens KIAA1008%3B component of the nucleolar exosome involved in RNA processing
chr6	3148125	3148346	-	DDB_G0293616	DDB_G0293616	NA
chr6	3150071	3150804	-	DDB_G0293618	pncA	catalyzes the reaction nicotinamide %2B H%3Csub%3E2%3C%2Fsub%3EO %3D nicotinate %2B NH%3Csub%3E3%3C%2Fsub%3E
chr6	3153008	3153382	+	DDB_G0293728	DDB_G0293728	NA
chr6	3154705	3157001	+	DDB_G0293730	DDB_G0293730	the TIM beta%2Falpha-barrel domain is found in phospholipase C (PLC) like phosphodiesterases
chr6	3157149	3158987	-	DDB_G0293620	DDB_G0293620	localizes to the centromeres
chr6	3159608	3162709	+	DDB_G0293622	DDB_G0293622	NA
chr6	3162861	3163388	+	DDB_G0293624	DDB_G0293624	NA
chr6	3164445	3166441	+	DDB_G0293626	DDB_G0293626	NA
chr6	3167249	3172262	+	DDB_G0293628	DDB_G0293628	NA
chr6	3173111	3173587	-	DDB_G0293732	DDB_G0293732_RTE	ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	3173627	3173697	+	DDB_G0295367	tRNA-His-GUG-9	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3176971	3180405	-	DDB_G0293630	DDB_G0293630_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank AF298209 for consensus full-length element
chr6	3180508	3181872	-	DDB_G0293632	DDB_G0293632_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank GenBank AF298209 for consensus full-length element
chr6	3182148	3182220	+	DDB_G0295369	tRNA-Asn-GUU-17	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3182350	3183333	+	DDB_G0293734	DDB_G0293734_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	3185294	3187147	+	DDB_G0293736	DDB_G0293736_RTE	partial ORF2 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	3188338	3188769	+	DDB_G0293522	ponA	anchors the cortical actin cytoskeleton to the plasma membrane
chr6	3189105	3189620	+	DDB_G0293634	ponE	similar to ponticulin (ponA)%2C a protein that anchors the actin cytoskeleton to the plasma membrane
chr6	3190337	3191311	-	DDB_G0293636	DDB_G0293636	similar to the conserved survival of motor neuron-related splicing factor 30 (SMNDC1%2C SPF30)%3B the tudor domain is found in many proteins that colocalize with ribonucleoprotein or single-strand DNA-associated complexes
chr6	3191821	3192787	-	DDB_G0293638	DDB_G0293638	NA
chr6	3193289	3194505	-	DDB_G0293528	arsA	homologous to bacterial genes that are involved in the transport of arsenate%2C selenate%2C and other anionic compounds outside the cell
chr6	3195274	3195720	+	DDB_G0293640	DDB_G0293640	NA
chr6	3198630	3200092	+	DDB_G0293644	DDB_G0293644	NA
chr6	3201771	3203360	+	DDB_G0293646	mcfN	ortholog of the human SLC25A3 and S. cerevisiae MIR1%2C which transports inorganic phosphate from the cytosol to the mitochondrion matrix %3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E 
chr6	3204161	3206066	-	DDB_G0293536	cupD	highly conserved protein family up-regulated by Ca2%2B%3B expressed throughout vegetative cells and in the cortex of aggregating cells
chr6	3208622	3208873	+	DDB_G0293648	DDB_G0293648	NA
chr6	3209379	3210400	-	DDB_G0293650	fahd2	ortholog of the human FAHD2A protein
chr6	3211810	3213777	-	DDB_G0293652	DDB_G0293652	NA
chr6	3215377	3219117	+	DDB_G0293654	gacE	NA
chr6	3219230	3221284	-	DDB_G0293656	fhkA	CAMK group%2C RAD53 family protein kinase%3B similar to mammalian cell cycle checkpoint kinases chk2%3B contains a forkhead-associated (FHA) domain%2C a phosphopeptide recognition domain found in many regulatory proteins%3Cbr%3E%3Cbr%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E The five fhk-X genes differ substantially in their response to the disruption of the retinoblastoma-like gene rblA. FhkA is substantially and highly signficantly upregulated in the ko strain%2C while none of the other genes show major changes. Consistent with its regulation%2C the fhkA promoter contains a putative E2F-type binding site (TTTGCGCCTTTT). Virtually all genes associated with replication fork progression are upregulated in the rblA disruptant%3B these include cdc45%2C all mcm genes%2C all gins genes%2C all rfc genes%2C four polA subunits%2C three polD subunits%2C two putatitive polE subunits%2C PCNA%2C the single-strand binding protein rfa1%2C the flap endonuclease repG%2C as well as DNA ligase-1 and topoisomerase-2. All these genes show overexpression factors ranging from 4 to 15. This suggests that among the fhk-X genes%2C fhkA may play the major role of replication fork protection in Dicty. The other fhk-X genes presumably play other%2C or subsidiary roles. %3Ci%3EHarry MacWilliams%2C June 2010%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FfhkA%22%3E There is more information on the wiki page%3C%2Fa%3E
chr6	3221806	3223129	-	DDB_G0293658	DDB_G0293658	NA
chr6	3223447	3223644	-	DDB_G0293660	DDB_G0293660	NA
chr6	3224777	3227220	+	DDB_G0293662	DDB_G0293662	NA
chr6	3227956	3232745	+	DDB_G0293664	DDB_G0293664	NA
chr6	3235027	3235099	+	DDB_G0295371	tRNA-Asn-GUU-18	transfers an asparagine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3235366	3236304	-	DDB_G0293666	DDB_G0293666	similar to terpene cyclases (C1) of the class 1 family of isoprenoid biosynthesis enzymes which are found in bacteria%2C fungi and plants
chr6	3236989	3238571	+	DDB_G0293738	cyp521A1	NA
chr6	3238981	3239889	+	DDB_G0293668	DDB_G0293668	NA
chr6	3241196	3241987	+	DDB_G0293670	DDB_G0293670	NA
chr6	3242621	3242905	+	DDB_G0293672	DDB_G0293672	NA
chr6	3243242	3245134	+	DDB_G0293674	DDB_G0293674	NA
chr6	3246015	3246355	+	DDB_G0293676	DDB_G0293676	similar to other Dictyostelium small coiled-coil proteins
chr6	3246808	3248517	+	DDB_G0293678	DDB_G0293678	NA
chr6	3248934	3249370	-	DDB_G0293680	DDB_G0293680	similar to the N-terminal region of metazoan malate dehydrogenase 1B
chr6	3249527	3251382	-	DDB_G0293740	ddx51	ortholog of H. sapiens DDX51 and S. cerevisiae DBP6 (Dead Box Protein 6)
chr6	3251577	3253485	+	DDB_G0293682	DDB_G0293682	NA
chr6	3253627	3257173	-	DDB_G0293532	dstC	NA
chr6	3259115	3261522	+	DDB_G0293782	DDB_G0293782	NA
chr6	3261758	3264389	+	DDB_G0293744	DDB_G0293744	NA
chr6	3265690	3266877	+	DDB_G0293746	DDB_G0293746	low level of similarity to mammalian PLK (polo-like kinase)%3B unlikely to function as a kinase as it does not contain a catalytic aspartate
chr6	3267287	3271342	+	DDB_G0293748	DDB_G0293748	NA
chr6	3272270	3275238	+	DDB_G0293750	dyrk2	similar to dual-specifity tyrosine-phosphorylation regulated kinases (DYRK)
chr6	3275662	3276820	-	DDB_G0293784	psmB5	subunit of the 20S proteasome (macropain)%2C the endopeptidase complex involved in an ATP%2Fubiquitin-dependent nonlysosomal proteolytic pathway%3B in eukaryotes composed of up to 28 subunits%2C which form a highly ordered ring-shaped structure (20S ring)
chr6	3277669	3278466	+	DDB_G0293742	rps2	protein component of the small (40S) ribosomal subunit%3B expressed in vegetative cells%2C and in prestalk cells during culmination
chr6	3279468	3282352	+	DDB_G0293752	psmD2	contains armadillo-like helical binding domain
chr6	3282657	3283193	+	DDB_G0293754	DDB_G0293754	contains a predicted signal sequence
chr6	3283369	3286763	-	DDB_G0293756	DDB_G0293756	NA
chr6	3287474	3288307	-	DDB_G0293786	DDB_G0293786	NA
chr6	3288367	3288726	-	DDB_G0294573	DDB_G0294573	similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0290637%22%3E%3Ci%3EDDB_G0290637%3C%2Fi%3E%3C%2Fa%3E
chr6	3289579	3290259	-	DDB_G0293758	H2Bv1	NA
chr6	3291080	3291424	+	DDB_G0293760	DDB_G0293760	NA
chr6	3291634	3291705	-	DDB_G0295395	tRNA-Glu-UUC-18	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chr6	3293162	3297313	+	DDB_G0293762	DDB_G0293762	highly similar to %3Ca href%3D%22%2Fdb%2Fcgi-bin%2Fgene_page.pl?primary_id%3DDDB_G0270060%22%3E%3Ci%3EDDB_G0270060%3C%2Fi%3E%3C%2Fa%3E%3B enriched in gametes
chr6	3297716	3299668	-	DDB_G0293764	DDB_G0293764_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	3299859	3299949	-	DDB_G0295393	tRNA-Ile-UAU-2	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3300203	3300688	+	DDB_G0293766	mth	NA
chr6	3300772	3302439	-	DDB_G0293768	fut9	CAZy family GT10%3B some proteins in the GT10 family help form the basis of blood group antigens
chr6	3303029	3306840	-	DDB_G0293770	DDB_G0293770	similar to H. sapiens USP4 and USP15 and S. cerevisiae UBP12
chr6	3307775	3310766	+	DDB_G0293772	vps52A	putative ortholog of S. cerevisiae VPS52%2C component of the GARP (Golgi-associated retrograde protein) complex
chr6	3310894	3312411	-	DDB_G0293774	DDB_G0293774	NA
chr6	3312699	3312789	+	DDB_G0295373	tRNA-Ile-UAU-1	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3312862	3313095	+	DDB_G0293776	DDB_G0293776	NA
chr6	3313981	3314364	-	DDB_G0293788	DDB_G0293788	contains a predicted signal peptide
chr6	3314676	3314906	-	DDB_G0293790	DDB_G0293790_ps	NA
chr6	3316597	3316935	+	DDB_G0293778	DDB_G0293778_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0287185%22%3EDDB_G0287185%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270454%22%3EDDB_G0270454%3C%2Fa%3E
chr6	3318747	3320302	+	DDB_G0293792	DDB_G0293792	NA
chr6	3321471	3322940	+	DDB_G0293794	DDB_G0293794	NA
chr6	3323921	3324064	+	DDB_G0293796	DDB_G0293796	NA
chr6	3324262	3324756	+	DDB_G0293798	DDB_G0293798	NA
chr6	3325552	3325633	+	DDB_G0295375	tRNA-Ser-UGA-11	transfers a serine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3326857	3330174	+	DDB_G0293818	DDB_G0293818_RTE	partial ORF2 of tRNA-specific non-long terminal repeat retrotransposon TRE3-C
chr6	3330793	3331227	-	DDB_G0349347	DDB_G0349347	NA
chr6	3332058	3332876	-	DDB_G0293820	DDB_G0293820	NA
chr6	3334534	3337072	+	DDB_G0293800	DDB_G0293800	atypical protein kinase%2C GTE group%3B contains ankyrin repeats%2C a bromodomain and a BTP%2FPOZ domain
chr6	3338059	3340862	-	DDB_G0293802	DDB_G0293802	contains a predicted signal sequence and a putative C-terminal transmembrane domain
chr6	3341293	3342700	-	DDB_G0293804	DDB_G0293804	NA
chr6	3343109	3343984	+	DDB_G0293806	DDB_G0293806	NA
chr6	3344068	3345472	-	DDB_G0293822	DDB_G0293822	NA
chr6	3346216	3347790	+	DDB_G0293824	med8	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 8%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr6	3348949	3352734	+	DDB_G0293826	DDB_G0293826	contains a central F-box domain
chr6	3352978	3353250	-	DDB_G0293808	DDB_G0293808	NA
chr6	3353625	3353780	+	DDB_G0293810	DDB_G0293810	conserved hypothetical Dictyostelium protein%3B contains no functional domains
chr6	3354232	3354274	+	DDB_G0295639	r62	predicted class I RNA%2C a small non-coding RNA (55-65 nt) containing highly conserved 5%27 and 3%27 ends
chr6	3355348	3357829	+	DDB_G0293812	DDB_G0293812	conserved in D. purpureum and P. pallidum%3B contains 12 putative transmembrane domains%3B C-terminal region similar to new-glue protein
chr6	3358255	3360920	+	DDB_G0293828	DDB_G0293828	NA
chr6	3361018	3362088	-	DDB_G0293814	DDB_G0293814	NA
chr6	3362954	3364014	-	DDB_G0293816	DDB_G0293816	NA
chr6	3365828	3367131	+	DDB_G0293830	DDB_G0293830	NA
chr6	3367295	3368415	-	DDB_G0293832	DDB_G0293832	NA
chr6	3369650	3371221	+	DDB_G0293836	DDB_G0293836	no homologs in other organisms%3B contains a predicted signal peptide and a possible C-terminal transmembrane domain
chr6	3371531	3372749	+	DDB_G0293838	DDB_G0293838	has similarity to the mammalian adiponectin receptor protein 1%3B contains 6 predicted transmembrane domains
chr6	3374878	3375705	+	DDB_G0293840	drcA	belongs to the glutathione S-transferase superfamily%3B catalzyes the first step in the breakdown of differentiation-inducing factor 1
chr6	3375777	3376388	-	DDB_G0293842	DDB_G0293842	NA
chr6	3376698	3378105	+	DDB_G0293834	wasA	colocalizes with clathrin spots suggesting involvement in endocytosis%2C does not localize to pseudopods in wild type%3B in SCAR depleted mutants WASP replaces the functions of SCAR and localizes to pseudopods
chr6	3378445	3379841	+	DDB_G0293844	csn4	subunit of the COP9 signalosome (CSN)%2C a complex of the ubiquitin-proteasome pathway composed of eight subunits (CSN1-8) 
chr6	3380322	3383976	+	DDB_G0293846	DDB_G0293846	similar to a D. purpureum protein
chr6	3384170	3384391	-	DDB_G0293852	DDB_G0293852_RTE	partial ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE3-B%3B refer to GenBank AF134170 for full-length consensus element
chr6	3384527	3385201	+	DDB_G0293892	DDB_G0293892_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE5-A%3B formerly known as DRE
chr6	3385382	3385497	+	DDB_G0294501	X69101	NA
chr6	3387585	3387658	+	DDB_G0295377	tRNA-Phe-GAA-14	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3388739	3389063	+	DDB_G0293854	DDB_G0293854	NA
chr6	3389682	3391511	-	DDB_G0293856	DDB_G0293856	NA
chr6	3392240	3394642	-	DDB_G0293858	DDB_G0293858	NA
chr6	3395178	3396098	+	DDB_G0293860	DDB_G0293860	NA
chr6	3396260	3397009	-	DDB_G0293862	DDB_G0293862	expressed in pstA and pstO cells and in pstAB cells during culmination
chr6	3398572	3400098	+	DDB_G0293864	DDB_G0293864	NA
chr6	3400165	3402141	-	DDB_G0293866	DDB_G0293866	%3Cb%3ECommunity annotation:%3C%2Fb%3E DDB_G0293866 has both N and C-terminal domains similar to aprataxin and contains a poly-ADP ribose binding domain. Aprataxin is suspected to play a role in several different DNA repair pathways%2C specifically by resolving abortive ligation intermediates [see Ahe et. al%2C Nature 443%2C 713-6 (2006)%3B Rass et al.%2C JBC 282%2C 9469-9474 (2007).]%3Cbr%3E DDB_GO293866 is 5-fold overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al%2C in preparation). Genes whose products are involved in replication-coupled DNA repair are generally overexpressed 3 to 6-fold in this strain%2C while genes in replication-independent repair pathways are overexpressed by smaller factors if at all. In mammalian cells%2C aprataxin interacts with XRCC1 and Ligase3%2C which are involved in (replication-independent) excision repair. The corresponding Dictyostelium genes are overexpressed less than twofold in the rblA-disruptant. %3Ci%3EHarry MacWilliams%2C September 2009%3C%2Fi%3E%3Cbr%3E %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FDDB_G0293866%22%3E There is more information on the wiki page%3C%2Fa%3E
chr6	3402442	3404079	-	DDB_G0293868	DDB_G0293868	NA
chr6	3404974	3406128	+	DDB_G0293850	alrA	involved in regulation of aggregate size%3B member of aldo-keto reductase family%2C which reduces C%3DO to C-OH in aldehydes and ketones
chr6	3406393	3406925	+	DDB_G0293870	DDB_G0293870	NA
chr6	3407225	3407306	-	DDB_G0295391	tRNA-Leu-AAG-11	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3407770	3409291	-	DDB_G0293872	idhB	catalyzes the reaction isocitrate %2B NAD%2B %3C%3D%3E 2-oxoglutarate %2B CO2 %2B NADH
chr6	3410167	3411303	+	DDB_G0293874	mcfZ	belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane%3B expressed in pstAO cells and in upper and lower cups during culmination%3Cbr%2F%3E%3Cbr%2F%3E %3Cb%3ECommunity annotation:%3C%2Fb%3E Overview of the %3Ca href%3D%22http:%2F%2Fwiki.dictybase.org%2Fdictywiki%2Findex.php%2FMitochondrial_Carrier_Family_%2528MCF%2529%22%3EMitochondrial Carrier Family (MCF)%3C%2Fa%3E%2C %3Ci%3EGerard Klein and Michel Satre%2C April 2007%3C%2Fi%3E
chr6	3411418	3412090	-	DDB_G0293848	phlp3	NA
chr6	3412404	3413152	+	DDB_G0293876	sf3a2	subunit of the splicing factor SF3A required for spliceosome assembly
chr6	3413755	3418080	+	DDB_G0293878	DDB_G0293878	NA
chr6	3418217	3419308	-	DDB_G0293880	DDB_G0293880	NA
chr6	3419922	3421439	+	DDB_G0293882	ptcA	NA
chr6	3421920	3423548	+	DDB_G0293884	DDB_G0293884	NA
chr6	3424368	3425363	+	DDB_G0293886	omt11	similar to plant and bacterial O-methyltransferases%3B expressed in pstO cells during culmination
chr6	3426309	3427418	+	DDB_G0293888	omt12	highly similar to plant and bacterial O-methyltransferases%3B expressed in pstA cells
chr6	3427824	3429093	+	DDB_G0293896	manA_ps	putative pseudogene%3B alpha-mannosidase family protein
chr6	3429586	3429880	+	DDB_G0293890	DDB_G0293890	related to hssA genes
chr6	3430565	3430646	+	DDB_G0295379	tRNA-Tyr-GUA-12	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3431147	3431587	+	DDB_G0293894	DDB_G0293894_RTE	ORF1 of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	3431954	3432036	-	DDB_G0295389	tRNA-Leu-UAA-15	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3432681	3433163	+	DDB_G0293906	DDB_G0293906	NA
chr6	3434517	3434891	-	DDB_G0293970	DDB_G0293970	NA
chr6	3436293	3437162	-	DDB_G0293908	DDB_G0293908_ps	putative pseudogene%3B similar to %3Ca href%3D%22gene%2FDDB_G0290067%22%3EcigB%3C%2Fa%3E family proteins
chr6	3438259	3448362	+	DDB_G0293902	pks44	putative type I iterative polyketide synthase
chr6	3448553	3448635	-	DDB_G0295387	tRNA-Leu-UAA-14	transfers a leucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3449223	3449707	+	DDB_G0293910	DDB_G0293910	NA
chr6	3449815	3459778	-	DDB_G0293912	pks45	putative type I iterative polyketide synthase
chr6	3460612	3466395	+	DDB_G0293958	DDB_G0293958	putative protein serine%2Fthreonine kinase%3B similar to vertebrate Nek kinases which are involved in regulation of mitosis
chr6	3466413	3468122	-	DDB_G0293974	DDB_G0293974	NA
chr6	3468362	3471415	-	DDB_G0293914	med15	putative ortholog of the poorly conserved mediator of RNA polymerase II transcription subunit 15%3B the mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery
chr6	3471747	3475867	+	DDB_G0293916	DDB_G0293916	NA
chr6	3475961	3479914	-	DDB_G0293918	tert	ortholog of the catalytic subunit of the reverse transcriptase complex
chr6	3481501	3484183	+	DDB_G0293920	DDB_G0293920	NA
chr6	3484508	3485653	+	DDB_G0293922	DDB_G0293922	NA
chr6	3485736	3487733	-	DDB_G0293976	DDB_G0293976	NA
chr6	3490466	3493218	+	DDB_G0293924	DDB_G0293924	NA
chr6	3493719	3497607	-	DDB_G0293900	mybA	contains three Myb DNA-binding domains
chr6	3500795	3504488	+	DDB_G0293978	gxcJ	NA
chr6	3504658	3506154	-	DDB_G0293926	DDB_G0293926	NA
chr6	3506582	3510001	-	DDB_G0293928	gxcZ	NA
chr6	3510935	3512082	-	DDB_G0293930	DDB_G0293930	similar to human ZDHHC16 (zinc finger DHHC domain-containing protein 16)%3B contains 4 putative transmembrane domains
chr6	3512665	3515735	+	DDB_G0293932	pakE	putative protein serine%2Fthreonine kinase%3B belongs to the PAKL subfamily of protein kinases%3B the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases%2C and other STE20-like kinases%3B stress-responsive kinase
chr6	3517422	3517964	+	DDB_G0293898	coaA	NA
chr6	3518793	3520083	+	DDB_G0293980	DDB_G0293980	NA
chr6	3520311	3525707	-	DDB_G0293934	DDB_G0293934	expressed in pstO cells and in upper cup during culmination
chr6	3528888	3532055	-	DDB_G0293936	exoc6	subunit of the exocyst complex%2C which targets secretory vesicles to active sites of exocytosis
chr6	3532350	3534137	+	DDB_G0293938	DDB_G0293938	NA
chr6	3534943	3535015	+	DDB_G0295381	tRNA-Ile-AAU-15	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3536699	3537715	+	DDB_G0293940	DDB_G0293940	NA
chr6	3537923	3551463	-	DDB_G0293982	DDB_G0293982	NA
chr6	3553305	3558082	+	DDB_G0293942	DDB_G0293942	NA
chr6	3558157	3558653	-	DDB_G0293944	DDB_G0293944	NA
chr6	3558856	3559281	+	DDB_G0293946	DDB_G0293946	conserved protein similar to S. cerevisiae EMI5%2C a mitochondrial protein which is involved in meiotic-specific transcription and sporulation
chr6	3559692	3562201	+	DDB_G0293948	DDB_G0293948	NA
chr6	3562548	3563694	+	DDB_G0293950	DDB_G0293950	NA
chr6	3563765	3568484	-	DDB_G0293984	ncapD2	component of the condensin I complex%2C required for conversion of interphase chromatin into mitotic condensed chromosomes
chr6	3568849	3570074	+	DDB_G0293952	qpct_ps	putative pseudogene%3B similar to glutaminyl-peptide cyclotransferase qpct 
chr6	3570187	3570762	-	DDB_G0293954	DDB_G0293954	NA
chr6	3571398	3572734	+	DDB_G0293986	qpct	catalyzes the reaction L-glutaminyl-peptide %3D 5-oxoprolyl-peptide %2B NH%3Csub%3E3%3C%2Fsub%3E during the biosynthesis of pyroglutamyl peptides
chr6	3572844	3573197	-	DDB_G0293956	DDB_G0293956	NA
chr6	3574106	3574179	+	DDB_G0295383	tRNA-Phe-GAA-15	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3574884	3578063	+	DDB_G0293964	DDB_G0293964_RTE	ORF2 protein encoding endonuclease and reverse transcriptase of tRNA-specific non-long terminal repeat retrotransposon TRE3-A%3B refer to GenBank AF134169 for full-length consensus element
chr6	3578831	3579867	-	DDB_G0293990	DDB_G0293990	NA
chr6	3580985	3582880	-	DDB_G0293904	redA	catalyzes the reaction NADPH %2B n oxidized hemoprotein %3D NADP(%2B) %2B n reduced hemoprotein%3B involved in the metabolism of compounds that control %3Ci%3EDictyostelium%3C%2Fi%3E cell differentiation
chr6	3583283	3586647	-	DDB_G0293988	DDB_G0293988	NA
chr6	3587001	3587074	-	DDB_G0295385	tRNA-Arg-CCU-1	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chr6	3588432	3588982	+	DDB_G0293992	DDB_G0293992	contains one C2 domain%2C which is is a Ca2%2B-dependent membrane-targeting module found in many cellular proteins involved in signal transduction or membrane trafficking
chr6	3589297	3591516	-	DDB_G0294004	DDB_G0294004	NA
chr6	3593501	3594005	-	DDB_G0294006	DDB_G0294006_ps	putative pseudogene%3B small fragment%2C similar to %3Ca href%3D%22%2Fgene%2FDDB_G0275563%22%3EDDB_G0275563%3C%2Fa%3E
chr6	3596687	3597276	+	DDB_G0293998	DDB_G0293998	NA
chr6	3598311	3598649	+	DDB_G0294008	DDB_G0294008_ps	putative pseudogene%3B similar to Dictyostelium genes %3Ca href%3D%22%2Fgene%2FDDB_G0287185%22%3EDDB_G0287185%3C%2Fa%3E and %3Ca href%3D%22%2Fgene%2FDDB_G0270454%22%3EDDB_G0270454%3C%2Fa%3E
chr6	3599142	3600382	-	DDB_G0294010	DDB_G0294010_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chr6	3600862	3602226	-	DDB_G0294002	DDB_G0294002_RTE	ORF1 protein of tRNA-specific non-long terminal repeat retrotransposon TRE5-B%3B refer to GenBank GenBank AF298209 for consensus full-length element
chrBF	803	1000	+	DDB_G0294342	DDB_G0294342_RTE	fused fragments of the DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chrBF	1048	2443	+	DDB_G0294344	DDB_G0294344_RTE	ORF2 protein fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chrBF	7210	9145	-	DDB_G0294346	DDB_G0294346_RTE	ORF1%2FORF3 protein fusion fragment of DIRS1 retrotransposon%3B refer to Genbank M11339 for full-length element
chrBF	12418	13862	-	DDB_G0294352	DDB_G0294352_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-B%3B refer to AF298202 for full-length consensus element
chrBF	16546	17754	-	DDB_G0294358	DDB_G0294358_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chrBF	17795	18114	-	DDB_G0294360	DDB_G0294360_RTE	ORF2 encoding reverse transcriptase (RT) and integrase (IN) proteins of long terminal repeat retrotransposon Skipper%3B refer to AF049230 for consensus element
chrBF	21031	21765	+	DDB_G0294362	DDB_G0294362_ps	putative pseudogene%3B fragment%2C nearly identical to %3Ca href%3D%22%2Fgene%2FDDB_G0295683%22%3EDDB_G0295683%3C%2Fa%3E
chrBF	22000	22740	+	DDB_G0294364	DDB_G0294364_ps	putative pseudogene%3B fragment%2C nearly identical to %3Ca href%3D%22%2Fgene%2FDDB_G0295683%22%3EDDB_G0295683%3C%2Fa%3E
chrBF	24012	24347	+	DDB_G0294366	DDB_G0294366	NA
chrBF	24816	25288	+	DDB_G0294368	DDB_G0294368	NA
chrBF	25629	26804	+	DDB_G0294370	DDB_G0294370_RTE	ORF2 encoding reverse transcriptase (RT) and RNaseH of long terminal repeat retrotransposon DGLT-B%3B refer to AF474004 for full-length consensus element
chrBF	26849	27667	+	DDB_G0294372	DDB_G0294372_RTE	ORF3 encoding the integrase protein of long terminal repeat retrotransposon DGLT-B%3B refer to AF474004 for full-length consensus element
chrBF	28204	28777	+	DDB_G0294374	DDB_G0294374_RTE	ORF4 encoding a zinc finger-containing protein of unknown function of long terminal repeat retrotransposon DGLT-B%3B refer to AF474004 for full-length consensus element
chrBF	29549	30575	-	DDB_G0294376	fcpA	shares a short region of similarity with H. sapiens small CTD phosphatase 2
chrBF	33501	33572	+	DDB_G0294667	tRNA-Thr-AGU-1	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chrBF	33977	34048	-	DDB_G0294669	tRNA-Thr-AGU-2	transfers a threonine residue to a growing polypeptide chain during protein synthesis%0A
chrBF	34769	35604	+	DDB_G0294380	DDB_G0294380	NA
chrBF	36063	36170	+	DDB_G0294382	DDB_G0294382	NA
chrBF	36573	37899	+	DDB_G0294384	DDB_G0294384_TE	ORF1 encoding a protein of unknown function of the putative DNA transposon DDT-A%3B refer to AF298201 for full-length consensus element
chrBF	39409	42518	+	DDB_G0294388	DDB_G0294388	NA
chrM	36	1658	+	DDB_G0294048	nad4	NA
chrM	1662	3128	+	DDB_G0294020	nad2	NA
chrM	3687	4994	+	DDB_G0294092	cox3	NA
chrM	5020	6363	+	DDB_G0294090	DidioMp05	enriched in gametes
chrM	6411	13862	+	DDB_G0294088	cox1%2F2	the cox1%2F2 gene encodes the cox1 and cox2 subunits
chrM	7957	8886	+	DDB_G0294421	ai2a	NA
chrM	8890	9678	+	DDB_G0294423	ai2b	NA
chrM	10734	11432	+	DDB_G0294425	ai3	NA
chrM	12725	13204	+	DDB_G0294080	ai4	NA
chrM	15103	16662	+	DDB_G0294012	atp1	alpha subunit of the central stalk of mitochondrial F1F0 ATP synthase%2C the enzyme complex responsible for ATP synthesis
chrM	18580	21997	+	DDB_G0294034	rnlA	the mitochondrial large ribosomal RNA is specifically degraded upon infection with %3Ci%3ELegionella pneumophila%3C%2Fi%3E
chrM	22457	22529	+	DDB_G0294637	tRNA-Gln-UUG-1	transfers a glutamine residue to a growing polypeptide chain during protein synthesis%0A
chrM	22874	24043	+	DDB_G0294078	cytB	NA
chrM	24054	24371	+	DDB_G0350614	atp8	mitochondrial ATPase subunit%3B UniProt record available: %3Ca href%3D%22http:%2F%2Fwww.uniprot.org%2Funiprot%2FA9CLV7%22 target%3D%22new%22%3EA9CLV7%3C%2Fa%3E
chrM	24361	24774	+	DDB_G0350617	atp4	mitochondrial ATPase subunitt%3B UniProt record available: %3Ca href%3D%22http:%2F%2Fwww.uniprot.org%2Funiprot%2FA9CLV8%22 target%3D%22new%22%3EA9CLV8%3C%2Fa%3E
chrM	24783	25145	+	DDB_G0294022	nad3	NA
chrM	25395	25467	+	DDB_G0294639	tRNA-Asn-GUU-1	transfers an asparagine residue to a growing polypeptide chain during protein synthesis 
chrM	25937	26077	+	DDB_G0305150	DDB_G0305150	similar to a bacterial protein of unknown function
chrM	27085	27157	+	DDB_G0294641	tRNA-Met-CAU-1	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chrM	27211	27282	+	DDB_G0294643	tRNA-Lys-UUU-1	transfers a lysine residue to a growing polypeptide chain during protein synthesis%0A
chrM	27292	27364	+	DDB_G0294645	tRNA-Arg-UCU-1	transfers an arginine residue to a growing polypeptide chain during protein synthesis%0A
chrM	27423	28376	+	DDB_G0294018	nad1	NA
chrM	28379	29059	+	DDB_G0294028	nad6	NA
chrM	29098	29171	+	DDB_G0294647	tRNA-Pro-UGG-1	transfers a proline residue to a growing polypeptide chain during protein synthesis%0A
chrM	29682	29948	+	DDB_G0294016	atp9	NA
chrM	30055	30128	+	DDB_G0294649	tRNA-Met-CAU-2	transfers a methionine residue to a growing polypeptide chain during protein synthesis%0A
chrM	30150	30779	+	DDB_G0294032	nad9	NA
chrM	30784	32004	+	DDB_G0294030	nad7	conserved core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)
chrM	32021	32755	+	DDB_G0294014	atp6	NA
chrM	32804	32884	+	DDB_G0294651	tRNA-Tyr-GUA-1	transfers a tyrosine residue to a growing polypeptide chain during protein synthesis%0A
chrM	33042	33560	+	DDB_G0294040	mrpl11	protein component of the mitochondrial large ribosomal subunit
chrM	33553	34122	+	DDB_G0294076	DidioMp21	NA
chrM	34094	34516	+	DDB_G0294074	mrps12	protein component of the small ribosomal subunit
chrM	34517	35005	+	DDB_G0294072	mrps7	protein component of the small ribosomal subunit
chrM	34996	35796	+	DDB_G0294036	mrpl2	protein component of the mitochondrial large ribosomal subunit
chrM	35789	36052	+	DDB_G0294044	mrps19	protein component of the small ribosomal subunit
chrM	36053	37330	+	DDB_G0294070	DidioMp26	contains the N terminus domain of the ribosomal S3 subunits%3B neighboring gene DidioMp27 contains the C terminus
chrM	37336	42558	+	DDB_G0294068	DidioMp27	contains the C terminus domain of the ribosomal S3 subunits%3B neighboring gene DidioMp26 contains the N terminus
chrM	42570	43004	+	DDB_G0294042	mrpl16	protein component of the mitochondrial large ribosomal subunit
chrM	43001	43390	+	DDB_G0294066	mrpl14	protein component of the mitochondrial large ribosomal subunit
chrM	43390	43956	+	DDB_G0294064	DidioMp30	NA
chrM	43953	44258	+	DDB_G0294062	mrps14	protein component of the small ribosomal subunit
chrM	44258	44716	+	DDB_G0294060	mrps8	protein component of the small ribosomal subunit
chrM	44706	45218	+	DDB_G0294038	mrpl6	protein component of the mitochondrial large ribosomal subunit
chrM	45220	45729	+	DDB_G0294058	mrps13	protein component of the small ribosomal subunit
chrM	45711	46094	+	DDB_G0294056	DidioMp35	NA
chrM	46099	48489	+	DDB_G0294054	DidioMp36	NA
chrM	48515	48588	+	DDB_G0294653	tRNA-Ile-GAU-1	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chrM	48588	48661	+	DDB_G0294655	tRNA-Ile-GAU-2	transfers an isoleucine residue to a growing polypeptide chain during protein synthesis%0A
chrM	48672	48744	+	DDB_G0294657	tRNA-His-GUG-1	transfers a histidine residue to a growing polypeptide chain during protein synthesis%0A
chrM	48766	50832	+	DDB_G0294052	nad11	subunit of NADH dehydrogenase%2C which catalyzes the reaction NADH %2B H%3Csup%3E%2B%3C%2Fsup%3E %2B ubiquinone %3C%3D%3E NAD%3Csup%3E%2B%3C%2Fsup%3E %2B ubiquinol
chrM	50823	52835	+	DDB_G0294026	nad5	NA
chrM	53032	53105	+	DDB_G0294659	tRNA-Phe-GAA-1	transfers a phenylalanine residue to a growing polypeptide chain during protein synthesis%0A
chrM	53158	54060	+	DDB_G0294046	mrps4	protein component of the small ribosomal subunit%3B involved in the transition of growth and development%3B ectopic expression of MRP4 in multiple human tumor cell lines suppressed cell proliferation through induction of  apoptotic cell death
chrM	54190	54924	+	DDB_G0294050	mrps2	protein component of the small ribosomal subunit
chrM	54971	55267	+	DDB_G0294024	nad4L	NA
chrM	55481	55552	+	DDB_G0294661	tRNA-Glu-UUC-1	transfers a glutamic acid residue to a growing polypeptide chain during protein synthesis%0A
chrR	4906	5589	-	DDB_G0295641	5S_rRNA-1	component of the ribosomal large (60S) subunit
chrR	7570	10810	-	DDB_G0295643	26S_rRNA-1	component of the ribosomal large (60S) subunit
chrR	11386	11547	-	DDB_G0295645	5.8S_rRNA-1	component of the ribosomal large (60S) subunit
chrR	11608	13748	-	DDB_G0295647	17S_rRNA-1	component of the ribosomal small (40S) subunit
chrR	71441	73311	+	DDB_G0295649	17S_rRNA-2	component of the ribosomal small (40S) subunit
chrR	73642	73803	+	DDB_G0295651	5.8S_rRNA-2	component of the ribosomal large (60S) subunit
chrR	74379	77619	+	DDB_G0295653	26S_rRNA-2	component of the ribosomal large (60S) subunit
chrR	79600	80283	+	DDB_G0295655	5S_rRNA-2	component of the ribosomal large (60S) subunit
