************************************************************************************************************ **************************** highly expressed miRs ************************************ ************************************************************************************************************ Number of genes: 530 Biological Process: GO.ID Term Annotated Significant Expected elim 1 GO:0006355 regulation of transcription, DNA-dependent 725 67 27.21 0.000001 2 GO:0030431 sleep 38 8 1.43 0.000066 3 GO:0001708 cell fate specification 85 12 3.19 0.000072 4 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 157 17 5.89 0.000081 5 GO:0007015 actin filament organization 116 14 4.35 0.000110 6 GO:0001745 compound eye morphogenesis 240 28 9.01 0.000120 7 GO:0051093 negative regulation of developmental process 134 15 5.03 0.000150 8 GO:0007469 antennal development 23 6 0.86 0.000160 9 GO:0007165 signal transduction 1195 86 44.85 0.000330 10 GO:0007365 periodic partitioning 37 7 1.39 0.000390 11 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 117 13 4.39 0.000430 12 GO:2000026 regulation of multicellular organismal development 305 27 11.45 0.000430 13 GO:0070983 dendrite guidance 19 5 0.71 0.000550 14 GO:0048523 negative regulation of cellular process 742 57 27.85 0.000680 15 GO:0007525 somatic muscle development 41 7 1.54 0.000740 16 GO:0001736 establishment of planar polarity 80 10 3.00 0.000780 17 GO:0007417 central nervous system development 207 24 7.77 0.000810 18 GO:0035023 regulation of Rho protein signal transduction 31 6 1.16 0.000890 19 GO:0045747 positive regulation of Notch signaling pathway 22 5 0.83 0.001130 20 GO:0035151 regulation of tube size, open tracheal system 44 7 1.65 0.001140 21 GO:0007271 synaptic transmission, cholinergic 2 2 0.08 0.001410 22 GO:0001964 startle response 15 4 0.56 0.001920 23 GO:0009888 tissue development 570 50 21.40 0.001930 24 GO:0019991 septate junction assembly 25 5 0.94 0.002070 25 GO:0001709 cell fate determination 132 15 4.95 0.002080 26 GO:0001710 mesodermal cell fate commitment 16 4 0.60 0.002480 27 GO:0007506 gonadal mesoderm development 8 3 0.30 0.002550 28 GO:0007438 oenocyte development 8 3 0.30 0.002550 29 GO:0007267 cell-cell signaling 494 33 18.54 0.002940 30 GO:0031987 locomotion involved in locomotory behavior 17 4 0.64 0.003150 31 GO:0048854 brain morphogenesis 17 4 0.64 0.003150 32 GO:0035317 imaginal disc-derived wing hair organization 43 8 1.61 0.003410 33 GO:0035011 melanotic encapsulation of foreign target 28 5 1.05 0.003490 34 GO:0007409 axonogenesis 265 25 9.95 0.003570 35 GO:0046845 branched duct epithelial cell fate determination, open tracheal system 9 3 0.34 0.003720 36 GO:0045595 regulation of cell differentiation 259 22 9.72 0.003840 37 GO:0016055 Wnt receptor signaling pathway 99 10 3.72 0.003920 38 GO:0046669 regulation of compound eye retinal cell programmed cell death 18 4 0.68 0.003930 39 GO:0035277 spiracle morphogenesis, open tracheal system 18 4 0.68 0.003930 40 GO:0060856 establishment of blood-brain barrier 18 4 0.68 0.003930 41 GO:0010001 glial cell differentiation 29 5 1.09 0.004090 42 GO:0035321 maintenance of imaginal disc-derived wing hair orientation 3 2 0.11 0.004110 43 GO:0031937 positive regulation of chromatin silencing 3 2 0.11 0.004110 44 GO:0034770 histone H4-K20 methylation 3 2 0.11 0.004110 45 GO:0007476 imaginal disc-derived wing morphogenesis 226 26 8.48 0.004490 46 GO:0048513 organ development 1115 93 41.85 0.004590 47 GO:0022414 reproductive process 837 50 31.42 0.004980 48 GO:0016321 female meiosis chromosome segregation 31 5 1.16 0.005510 49 GO:0048749 compound eye development 301 35 11.30 0.005670 50 GO:0008045 motor axon guidance 44 6 1.65 0.005670 51 GO:0045466 R7 cell differentiation 44 6 1.65 0.005670 52 GO:0048813 dendrite morphogenesis 159 17 5.97 0.005800 53 GO:0043401 steroid hormone mediated signaling pathway 20 4 0.75 0.005870 54 GO:0048609 multicellular organismal reproductive process 752 42 28.23 0.005870 55 GO:0006461 protein complex assembly 122 11 4.58 0.006070 56 GO:0030855 epithelial cell differentiation 32 5 1.20 0.006330 57 GO:0010160 formation of organ boundary 45 6 1.69 0.006340 58 GO:0030534 adult behavior 107 10 4.02 0.006800 59 GO:0016337 cell-cell adhesion 75 8 2.82 0.006870 60 GO:0016199 axon midline choice point recognition 21 4 0.79 0.007040 61 GO:0008587 imaginal disc-derived wing margin morphogenesis 46 6 1.73 0.007070 62 GO:0003006 developmental process involved in reproduction 554 35 20.79 0.007210 63 GO:0051345 positive regulation of hydrolase activity 33 5 1.24 0.007240 64 GO:0048285 organelle fission 197 15 7.39 0.007270 65 GO:0046903 secretion 179 14 6.72 0.007450 66 GO:0023057 negative regulation of signaling 161 13 6.04 0.007530 67 GO:0007420 brain development 110 13 4.13 0.007580 68 GO:0018202 peptidyl-histidine modification 4 2 0.15 0.008020 69 GO:0018022 peptidyl-lysine methylation 4 2 0.15 0.008020 70 GO:2000045 regulation of G1/S transition of mitotic cell cycle 4 2 0.15 0.008020 71 GO:0021675 nerve development 4 2 0.15 0.008020 72 GO:0010648 negative regulation of cell communication 163 13 6.12 0.008330 73 GO:0051128 regulation of cellular component organization 415 30 15.58 0.008340 74 GO:0048468 cell development 977 76 36.67 0.008350 75 GO:0040011 locomotion 456 38 17.12 0.008350 76 GO:0045214 sarcomere organization 22 4 0.83 0.008350 77 GO:0007259 JAK-STAT cascade 22 4 0.83 0.008350 78 GO:0010740 positive regulation of intracellular protein kinase cascade 22 4 0.83 0.008350 79 GO:0007480 imaginal disc-derived leg morphogenesis 48 6 1.80 0.008700 80 GO:0035295 tube development 146 12 5.48 0.008780 81 GO:0042693 muscle cell fate commitment 12 3 0.45 0.008960 82 GO:0048610 cellular process involved in reproduction 529 31 19.86 0.009000 83 GO:0065007 biological regulation 2915 194 109.42 0.009120 84 GO:0048585 negative regulation of response to stimulus 165 13 6.19 0.009180 85 GO:0007427 epithelial cell migration, open tracheal system 35 5 1.31 0.009310 86 GO:0023052 signaling 1552 107 58.25 0.009520 87 GO:0002121 inter-male aggressive behavior 49 6 1.84 0.009610 88 GO:0007389 pattern specification process 460 38 17.27 0.009770 89 GO:0008360 regulation of cell shape 113 10 4.24 0.009860 90 GO:0019953 sexual reproduction 687 38 25.79 0.010050 91 GO:0007626 locomotory behavior 132 14 4.95 0.010450 92 GO:0060341 regulation of cellular localization 97 9 3.64 0.010470 93 GO:0044057 regulation of system process 65 7 2.44 0.010630 94 GO:0048646 anatomical structure formation involved in morphogenesis 440 36 16.52 0.011110 95 GO:0007605 sensory perception of sound 24 4 0.90 0.011440 96 GO:0030178 negative regulation of Wnt receptor signaling pathway 24 4 0.90 0.011440 97 GO:0001737 establishment of imaginal disc-derived wing hair orientation 24 4 0.90 0.011440 98 GO:0030111 regulation of Wnt receptor signaling pathway 51 6 1.91 0.011630 99 GO:0007423 sensory organ development 425 45 15.95 0.011690 100 GO:0060284 regulation of cell development 190 17 7.13 0.011880 101 GO:0006366 transcription from RNA polymerase II promoter 384 38 14.41 0.012010 102 GO:0006357 regulation of transcription from RNA polymerase II promoter 330 35 12.39 0.012220 103 GO:0000280 nuclear division 190 14 7.13 0.012250 104 GO:0007276 gamete generation 674 37 25.30 0.012330 105 GO:0007219 Notch signaling pathway 90 12 3.38 0.012700 106 GO:0035310 notum cell fate specification 5 2 0.19 0.013030 107 GO:0007500 mesodermal cell fate determination 5 2 0.19 0.013030 108 GO:0046426 negative regulation of JAK-STAT cascade 5 2 0.19 0.013030 109 GO:0007604 phototransduction, UV 5 2 0.19 0.013030 110 GO:0009589 detection of UV 5 2 0.19 0.013030 111 GO:0048738 cardiac muscle tissue development 5 2 0.19 0.013030 112 GO:0048098 antennal joint development 5 2 0.19 0.013030 113 GO:0006964 positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative b... 5 2 0.19 0.013030 114 GO:0060250 germ-line stem-cell niche homeostasis 5 2 0.19 0.013030 115 GO:0042752 regulation of circadian rhythm 38 5 1.43 0.013140 116 GO:0042067 establishment of ommatidial planar polarity 53 6 1.99 0.013930 117 GO:0045433 male courtship behavior, veined wing generated song production 14 3 0.53 0.014030 118 GO:0009649 entrainment of circadian clock 14 3 0.53 0.014030 119 GO:0048800 antennal morphogenesis 14 3 0.53 0.014030 120 GO:0009968 negative regulation of signal transduction 156 12 5.86 0.014380 121 GO:0001505 regulation of neurotransmitter levels 120 10 4.50 0.014660 122 GO:0006468 protein phosphorylation 315 20 11.82 0.015110 123 GO:0045596 negative regulation of cell differentiation 103 9 3.87 0.015130 124 GO:0007367 segment polarity determination 26 4 0.98 0.015180 125 GO:0035017 cuticle pattern formation 26 4 0.98 0.015180 126 GO:0051674 localization of cell 233 19 8.75 0.015760 127 GO:0016477 cell migration 214 18 8.03 0.016010 128 GO:0014706 striated muscle tissue development 140 11 5.25 0.016180 129 GO:0006915 apoptosis 159 12 5.97 0.016510 130 GO:0008344 adult locomotory behavior 55 6 2.06 0.016530 131 GO:0048699 generation of neurons 594 52 22.30 0.016700 132 GO:0060537 muscle tissue development 141 11 5.29 0.016980 133 GO:0007549 dosage compensation 15 3 0.56 0.017050 134 GO:0016545 male courtship behavior, veined wing vibration 15 3 0.56 0.017050 135 GO:0006919 activation of caspase activity 15 3 0.56 0.017050 136 GO:0050954 sensory perception of mechanical stimulus 27 4 1.01 0.017300 137 GO:0007400 neuroblast fate determination 27 4 1.01 0.017300 138 GO:0048806 genitalia development 27 4 1.01 0.017300 139 GO:0010629 negative regulation of gene expression 325 29 12.20 0.017840 140 GO:0051225 spindle assembly 41 5 1.54 0.017910 141 GO:0007166 cell surface receptor linked signaling pathway 671 45 25.19 0.018210 142 GO:0007422 peripheral nervous system development 89 8 3.34 0.018340 143 GO:0035637 multicellular organismal signaling 263 19 9.87 0.018360 144 GO:0019226 transmission of nerve impulse 263 19 9.87 0.018360 145 GO:0045665 negative regulation of neuron differentiation 6 2 0.23 0.019070 146 GO:0030042 actin filament depolymerization 6 2 0.23 0.019070 147 GO:0042133 neurotransmitter metabolic process 6 2 0.23 0.019070 148 GO:0045317 equator specification 6 2 0.23 0.019070 149 GO:0008366 axon ensheathment 6 2 0.23 0.019070 150 GO:0048104 establishment of body hair or bristle planar orientation 6 2 0.23 0.019070 Molecular Function: GO.ID Term Annotated Significant Expected elim 1 GO:0043565 sequence-specific DNA binding 294 32 10.70 0.000000026 2 GO:0003700 sequence-specific DNA binding transcription factor activity 439 43 15.98 0.000005800 3 GO:0005089 Rho guanyl-nucleotide exchange factor activity 25 6 0.91 0.000220000 4 GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity 52 8 1.89 0.000530000 5 GO:0003729 mRNA binding 192 17 6.99 0.000630000 6 GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor a... 44 7 1.60 0.000960000 7 GO:0008134 transcription factor binding 110 11 4.00 0.002160000 8 GO:0008376 acetylgalactosaminyltransferase activity 18 4 0.66 0.003520000 9 GO:0000155 two-component sensor activity 3 2 0.11 0.003870000 10 GO:0042799 histone methyltransferase activity (H4-K20 specific) 3 2 0.11 0.003870000 11 GO:0003707 steroid hormone receptor activity 20 4 0.73 0.005260000 12 GO:0004871 signal transducer activity 469 33 17.07 0.005410000 13 GO:0015279 store-operated calcium channel activity 4 2 0.15 0.007550000 14 GO:0004672 protein kinase activity 271 20 9.86 0.008650000 15 GO:0004674 protein serine/threonine kinase activity 193 14 7.02 0.010850000 16 GO:0000976 transcription regulatory region sequence-specific DNA binding 68 7 2.47 0.011500000 17 GO:0004370 glycerol kinase activity 5 2 0.18 0.012280000 18 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 14 3 0.51 0.012900000 19 GO:0019199 transmembrane receptor protein kinase activity 26 4 0.95 0.013680000 20 GO:0005515 protein binding 1334 69 48.54 0.013900000 21 GO:0022843 voltage-gated cation channel activity 40 5 1.46 0.014350000 22 GO:0008812 choline dehydrogenase activity 15 3 0.55 0.015700000 23 GO:0008270 zinc ion binding 899 45 32.71 0.016980000 24 GO:0019198 transmembrane receptor protein phosphatase activity 6 2 0.22 0.017980000 25 GO:0008301 DNA bending activity 6 2 0.22 0.017980000 26 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 6 2 0.22 0.017980000 27 GO:0008574 plus-end-directed microtubule motor activity 6 2 0.22 0.017980000 28 GO:0008047 enzyme activator activity 92 8 3.35 0.018630000 29 GO:0003725 double-stranded RNA binding 16 3 0.58 0.018810000 30 GO:0005516 calmodulin binding 30 4 1.09 0.022390000 31 GO:0004864 protein phosphatase inhibitor activity 7 2 0.25 0.024570000 32 GO:0015924 mannosyl-oligosaccharide mannosidase activity 7 2 0.25 0.024570000 33 GO:0004713 protein tyrosine kinase activity 46 5 1.67 0.025070000 34 GO:0003682 chromatin binding 80 7 2.91 0.026100000 35 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 47 5 1.71 0.027240000 36 GO:0044212 transcription regulatory region DNA binding 83 7 3.02 0.031140000 37 GO:0022832 voltage-gated channel activity 49 5 1.78 0.031950000 38 GO:0005244 voltage-gated ion channel activity 49 5 1.78 0.031950000 39 GO:0001012 RNA polymerase II regulatory region DNA binding 49 5 1.78 0.031950000 40 GO:0017124 SH3 domain binding 8 2 0.29 0.031980000 41 GO:0004683 calmodulin-dependent protein kinase activity 8 2 0.29 0.031980000 42 GO:0004000 adenosine deaminase activity 8 2 0.29 0.031980000 43 GO:0005096 GTPase activator activity 66 6 2.40 0.032410000 44 GO:0001067 regulatory region nucleic acid binding 84 7 3.06 0.032960000 45 GO:0000975 regulatory region DNA binding 84 7 3.06 0.032960000 46 GO:0005267 potassium channel activity 34 4 1.24 0.033840000 82 GO:0042302 structural constituent of cuticle 144 10 5.24 0.037280000 83 GO:0004714 transmembrane receptor protein tyrosine kinase activity 21 3 0.76 0.039100000 84 GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor a... 21 3 0.76 0.039100000 85 GO:0008514 organic anion transmembrane transporter activity 9 2 0.33 0.040140000 86 GO:0005245 voltage-gated calcium channel activity 9 2 0.33 0.040140000 87 GO:0019212 phosphatase inhibitor activity 9 2 0.33 0.040140000 88 GO:0004629 phospholipase C activity 9 2 0.33 0.040140000 89 GO:0005070 SH3/SH2 adaptor activity 10 2 0.36 0.048990000 90 GO:0003714 transcription corepressor activity 23 3 0.84 0.049380000 Cellular Component: GO.ID Term Annotated Significant Expected elim 1 GO:0005886 plasma membrane 624 52 25.38 0.000083 2 GO:0005634 nucleus 1885 104 76.66 0.000290 3 GO:0016027 inaD signaling complex 10 4 0.41 0.000460 4 GO:0008076 voltage-gated potassium channel complex 19 5 0.77 0.000780 5 GO:0044456 synapse part 118 13 4.80 0.000970 6 GO:0045179 apical cortex 29 5 1.18 0.005730 7 GO:0030018 Z disc 20 4 0.81 0.007770 8 GO:0031594 neuromuscular junction 32 5 1.30 0.008800 9 GO:0005795 Golgi stack 33 5 1.34 0.010040 10 GO:0048471 perinuclear region of cytoplasm 34 5 1.38 0.011390 11 GO:0030672 synaptic vesicle membrane 5 2 0.20 0.015200 12 GO:0043005 neuron projection 96 9 3.90 0.015840 13 GO:0097060 synaptic membrane 37 5 1.50 0.016160 14 GO:0016607 nuclear speck 14 3 0.57 0.017380 15 GO:0044459 plasma membrane part 352 30 14.32 0.017890 16 GO:0044431 Golgi apparatus part 83 8 3.38 0.019190 17 GO:0005700 polytene chromosome 116 10 4.72 0.019460 18 GO:0030424 axon 68 7 2.77 0.019990 19 GO:0035062 omega speckle 6 2 0.24 0.022190 20 GO:0005818 aster 7 2 0.28 0.030240 21 GO:0045180 basal cortex 7 2 0.28 0.030240 22 GO:0045211 postsynaptic membrane 30 4 1.22 0.031980 23 GO:0016604 nuclear body 46 5 1.87 0.037850 24 GO:0000805 X chromosome 8 2 0.33 0.039260 25 GO:0046536 dosage compensation complex 8 2 0.33 0.039260 26 GO:0016456 X chromosome located dosage compensation complex, transcription activating 8 2 0.33 0.039260 27 GO:0033267 axon part 32 4 1.30 0.039400 36 GO:0005667 transcription factor complex 98 8 3.99 0.045620 37 GO:0031332 RNAi effector complex 9 2 0.37 0.049140 38 GO:0000803 sex chromosome 9 2 0.37 0.049140 39 GO:0030665 clathrin coated vesicle membrane 9 2 0.37 0.049140 40 GO:0016442 RNA-induced silencing complex 9 2 0.37 0.049140 ************************************************************************************************************ **************************** lowly expressed miRs ************************************ ************************************************************************************************************ Number of genes: 2035 Biological Process: GO.ID Term Annotated Significant Expected elim 1 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 157 55 23.37 2.10e-10 2 GO:0007411 axon guidance 199 73 29.62 2.80e-08 3 GO:0007520 myoblast fusion 29 17 4.32 6.90e-08 4 GO:0007475 apposition of dorsal and ventral imaginal disc-derived wing surfaces 18 13 2.68 6.90e-08 5 GO:0035556 intracellular signal transduction 433 137 64.44 7.80e-08 6 GO:0007476 imaginal disc-derived wing morphogenesis 226 77 33.63 1.80e-07 7 GO:0007422 peripheral nervous system development 89 33 13.25 1.90e-07 8 GO:0007616 long-term memory 52 23 7.74 3.60e-07 9 GO:0006355 regulation of transcription, DNA-dependent 725 186 107.90 5.70e-07 10 GO:0046331 lateral inhibition 208 58 30.96 7.80e-07 11 GO:0007498 mesoderm development 99 34 14.73 1.00e-06 12 GO:0007507 heart development 79 29 11.76 1.30e-06 13 GO:0007391 dorsal closure 95 35 14.14 2.20e-06 14 GO:0048813 dendrite morphogenesis 159 51 23.66 3.10e-06 15 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 117 37 17.41 3.30e-06 16 GO:0001700 embryonic development via the syncytial blastoderm 170 62 25.30 3.80e-06 17 GO:0007424 open tracheal system development 195 69 29.02 5.10e-06 18 GO:0007155 cell adhesion 191 69 28.43 5.10e-06 19 GO:0008045 motor axon guidance 44 19 6.55 5.70e-06 20 GO:0007420 brain development 110 38 16.37 6.20e-06 21 GO:0007186 G-protein coupled receptor protein signaling pathway 203 58 30.21 7.70e-06 22 GO:0007156 homophilic cell adhesion 31 15 4.61 1.00e-05 23 GO:0008347 glial cell migration 31 15 4.61 1.00e-05 24 GO:0008360 regulation of cell shape 113 39 16.82 1.20e-05 25 GO:0007398 ectoderm development 22 12 3.27 1.70e-05 26 GO:0042676 compound eye cone cell fate commitment 11 8 1.64 2.60e-05 27 GO:0048190 wing disc dorsal/ventral pattern formation 48 19 7.14 2.60e-05 28 GO:0016079 synaptic vesicle exocytosis 56 21 8.33 2.60e-05 29 GO:0007409 axonogenesis 265 102 39.44 2.90e-05 30 GO:0006911 phagocytosis, engulfment 192 50 28.57 3.40e-05 31 GO:0055059 asymmetric neuroblast division 30 14 4.46 3.40e-05 32 GO:0043401 steroid hormone mediated signaling pathway 20 11 2.98 3.50e-05 33 GO:0007517 muscle organ development 233 89 34.68 3.50e-05 34 GO:0007165 signal transduction 1195 336 177.85 4.70e-05 35 GO:0045610 regulation of hemocyte differentiation 24 12 3.57 5.30e-05 36 GO:0051124 synaptic growth at neuromuscular junction 69 26 10.27 6.20e-05 37 GO:0007276 gamete generation 674 165 100.31 7.00e-05 38 GO:0008016 regulation of heart contraction 15 9 2.23 7.50e-05 39 GO:0006468 protein phosphorylation 315 75 46.88 7.70e-05 40 GO:0007419 ventral cord development 33 14 4.91 1.20e-04 41 GO:0008039 synaptic target recognition 10 7 1.49 1.30e-04 42 GO:0008345 larval locomotory behavior 19 10 2.83 1.30e-04 43 GO:0006936 muscle contraction 19 10 2.83 1.30e-04 44 GO:0007379 segment specification 37 15 5.51 1.30e-04 45 GO:0007464 R3/R4 cell fate commitment 16 9 2.38 1.50e-04 46 GO:0007413 axonal fasciculation 16 9 2.38 1.50e-04 47 GO:0042051 compound eye photoreceptor development 70 25 10.42 1.70e-04 48 GO:0007268 synaptic transmission 256 87 38.10 1.70e-04 49 GO:0009968 negative regulation of signal transduction 156 49 23.22 1.80e-04 50 GO:0008344 adult locomotory behavior 55 19 8.19 2.20e-04 51 GO:0007451 dorsal/ventral lineage restriction, imaginal disc 8 6 1.19 2.30e-04 52 GO:0008406 gonad development 51 18 7.59 2.40e-04 53 GO:0016331 morphogenesis of embryonic epithelium 114 46 16.97 2.70e-04 54 GO:0042461 photoreceptor cell development 85 34 12.65 2.80e-04 55 GO:0007440 foregut morphogenesis 11 7 1.64 3.00e-04 56 GO:0042330 taxis 248 90 36.91 3.10e-04 57 GO:0007298 border follicle cell migration 74 23 11.01 3.10e-04 58 GO:0016202 regulation of striated muscle tissue development 54 21 8.04 3.50e-04 59 GO:0000904 cell morphogenesis involved in differentiation 401 149 59.68 3.70e-04 60 GO:0007369 gastrulation 75 23 11.16 3.80e-04 61 GO:0008355 olfactory learning 53 18 7.89 4.10e-04 62 GO:0043085 positive regulation of catalytic activity 71 22 10.57 4.30e-04 63 GO:0002121 inter-male aggressive behavior 49 17 7.29 4.50e-04 64 GO:0016337 cell-cell adhesion 75 33 11.16 4.70e-04 65 GO:0016584 nucleosome positioning 4 4 0.60 4.90e-04 66 GO:0008348 negative regulation of antimicrobial humoral response 4 4 0.60 4.90e-04 67 GO:0003383 apical constriction 4 4 0.60 4.90e-04 68 GO:0048099 anterior/posterior lineage restriction, imaginal disc 4 4 0.60 4.90e-04 69 GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 4 4 0.60 4.90e-04 70 GO:0008586 imaginal disc-derived wing vein morphogenesis 41 15 6.10 5.00e-04 71 GO:0048610 cellular process involved in reproduction 529 129 78.73 5.20e-04 72 GO:0001745 compound eye morphogenesis 240 85 35.72 5.60e-04 73 GO:0007349 cellularization 96 27 14.29 5.80e-04 74 GO:0002385 mucosal immune response 9 6 1.34 6.00e-04 75 GO:0007015 actin filament organization 116 31 17.26 6.30e-04 76 GO:0048749 compound eye development 301 104 44.80 6.30e-04 77 GO:0048488 synaptic vesicle endocytosis 46 16 6.85 6.30e-04 78 GO:0048100 wing disc anterior/posterior pattern formation 12 7 1.79 6.30e-04 79 GO:0007526 larval somatic muscle development 12 7 1.79 6.30e-04 80 GO:0007431 salivary gland development 163 44 24.26 6.40e-04 81 GO:0030036 actin cytoskeleton organization 192 57 28.57 6.50e-04 82 GO:0001667 ameboidal cell migration 42 15 6.25 6.70e-04 83 GO:0051093 negative regulation of developmental process 134 41 19.94 6.80e-04 84 GO:0019730 antimicrobial humoral response 106 32 15.78 6.90e-04 85 GO:0030010 establishment of cell polarity 30 12 4.46 7.20e-04 86 GO:0007224 smoothened signaling pathway 51 17 7.59 7.50e-04 87 GO:0007635 chemosensory behavior 100 34 14.88 7.60e-04 88 GO:0070983 dendrite guidance 19 9 2.83 7.80e-04 89 GO:0007444 imaginal disc development 482 147 71.73 8.00e-04 90 GO:0045466 R7 cell differentiation 44 19 6.55 8.90e-04 91 GO:0045793 positive regulation of cell size 23 10 3.42 9.20e-04 92 GO:0051128 regulation of cellular component organization 415 115 61.76 9.30e-04 93 GO:0030713 ovarian follicle cell stalk formation 16 8 2.38 9.90e-04 94 GO:0007400 neuroblast fate determination 27 11 4.02 9.90e-04 95 GO:0060284 regulation of cell development 190 62 28.28 1.01e-03 96 GO:0035023 regulation of Rho protein signal transduction 31 12 4.61 1.01e-03 97 GO:0007417 central nervous system development 207 70 30.81 1.07e-03 98 GO:0007480 imaginal disc-derived leg morphogenesis 48 16 7.14 1.07e-03 99 GO:0000910 cytokinesis 90 25 13.39 1.12e-03 100 GO:0007442 hindgut morphogenesis 58 21 8.63 1.16e-03 101 GO:2000026 regulation of multicellular organismal development 305 100 45.39 1.16e-03 102 GO:0072499 photoreceptor cell axon guidance 7 5 1.04 1.17e-03 103 GO:0042694 muscle cell fate specification 7 5 1.04 1.17e-03 104 GO:0008356 asymmetric cell division 76 27 11.31 1.20e-03 105 GO:0048103 somatic stem cell division 40 20 5.95 1.27e-03 106 GO:0050803 regulation of synapse structure and activity 73 27 10.86 1.30e-03 107 GO:0035212 cell competition in a multicellular organism 10 6 1.49 1.32e-03 108 GO:0042078 germ-line stem cell division 36 13 5.36 1.35e-03 109 GO:0008361 regulation of cell size 55 22 8.19 1.35e-03 110 GO:0045746 negative regulation of Notch signaling pathway 24 10 3.57 1.37e-03 111 GO:0030855 epithelial cell differentiation 32 15 4.76 1.39e-03 112 GO:0046667 compound eye retinal cell programmed cell death 28 11 4.17 1.42e-03 113 GO:0007416 synapse assembly 89 36 13.25 1.51e-03 114 GO:0080090 regulation of primary metabolic process 1069 264 159.10 1.53e-03 115 GO:0048522 positive regulation of cellular process 558 157 83.05 1.58e-03 116 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 68 20 10.12 1.60e-03 117 GO:0045597 positive regulation of cell differentiation 17 8 2.53 1.63e-03 118 GO:0007610 behavior 450 135 66.97 1.72e-03 119 GO:0007166 cell surface receptor linked signaling pathway 671 177 99.86 1.72e-03 120 GO:0007389 pattern specification process 460 129 68.46 1.74e-03 121 GO:0008038 neuron recognition 65 31 9.67 1.74e-03 122 GO:0007264 small GTPase mediated signal transduction 205 61 30.51 1.79e-03 123 GO:0007465 R7 cell fate commitment 21 9 3.13 1.88e-03 124 GO:0016199 axon midline choice point recognition 21 9 3.13 1.88e-03 125 GO:0007049 cell cycle 708 133 105.37 1.89e-03 126 GO:0001709 cell fate determination 132 42 19.65 1.91e-03 127 GO:0042306 regulation of protein import into nucleus 33 12 4.91 1.91e-03 128 GO:0016477 cell migration 214 68 31.85 1.99e-03 129 GO:0007350 blastoderm segmentation 194 53 28.87 2.21e-03 130 GO:0048468 cell development 977 300 145.40 2.29e-03 131 GO:0035072 ecdysone-mediated induction of salivary gland cell autophagic cell death 11 6 1.64 2.53e-03 132 GO:0031532 actin cytoskeleton reorganization 11 6 1.64 2.53e-03 133 GO:0022416 bristle development 95 25 14.14 2.54e-03 134 GO:0008362 chitin-based embryonic cuticle biosynthetic process 18 8 2.68 2.56e-03 135 GO:0051241 negative regulation of multicellular organismal process 18 8 2.68 2.56e-03 136 GO:0031323 regulation of cellular metabolic process 1102 272 164.01 2.62e-03 137 GO:0010001 glial cell differentiation 29 13 4.32 2.70e-03 138 GO:0042478 regulation of eye photoreceptor cell development 11 8 1.64 2.72e-03 139 GO:0016476 regulation of embryonic cell shape 30 11 4.46 2.72e-03 140 GO:0032312 regulation of ARF GTPase activity 8 5 1.19 2.74e-03 141 GO:0016203 muscle attachment 35 15 5.21 2.75e-03 142 GO:0040018 positive regulation of multicellular organism growth 22 9 3.27 2.77e-03 143 GO:0050804 regulation of synaptic transmission 43 14 6.40 2.77e-03 144 GO:0006338 chromatin remodeling 43 14 6.40 2.77e-03 145 GO:0090130 tissue migration 43 14 6.40 2.77e-03 146 GO:0030707 ovarian follicle cell development 202 55 30.06 2.79e-03 147 GO:0007455 eye-antennal disc morphogenesis 39 13 5.80 3.08e-03 148 GO:0050767 regulation of neurogenesis 100 35 14.88 3.08e-03 149 GO:0048546 digestive tract morphogenesis 63 26 9.38 3.20e-03 150 GO:0031328 positive regulation of cellular biosynthetic process 266 82 39.59 3.22e-03 Molecular Function: GO.ID Term Annotated Significant Expected elim 1 GO:0005515 protein binding 1334 337 197.06 4.300e-12 2 GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor a... 44 25 6.50 1.200e-10 3 GO:0003700 sequence-specific DNA binding transcription factor activity 439 138 64.85 1.200e-09 4 GO:0008270 zinc ion binding 899 196 132.80 2.000e-09 5 GO:0043565 sequence-specific DNA binding 294 96 43.43 2.100e-08 6 GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity 52 22 7.68 1.400e-06 7 GO:0005543 phospholipid binding 129 38 19.06 1.300e-05 8 GO:0005516 calmodulin binding 30 14 4.43 3.100e-05 9 GO:0003707 steroid hormone receptor activity 20 11 2.95 3.300e-05 10 GO:0050839 cell adhesion molecule binding 21 11 3.10 5.900e-05 11 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding 18 10 2.66 6.700e-05 12 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 47 23 6.94 9.600e-05 13 GO:0003924 GTPase activity 142 37 20.98 2.900e-04 14 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 6 5 0.89 3.700e-04 15 GO:0003730 mRNA 3'-UTR binding 25 11 3.69 4.200e-04 16 GO:0019899 enzyme binding 125 33 18.46 4.700e-04 17 GO:0004674 protein serine/threonine kinase activity 193 46 28.51 5.200e-04 18 GO:0003714 transcription corepressor activity 23 10 3.40 8.700e-04 19 GO:0005509 calcium ion binding 214 49 31.61 9.200e-04 20 GO:0005083 small GTPase regulator activity 100 38 14.77 1.130e-03 21 GO:0016015 morphogen activity 7 5 1.03 1.130e-03 22 GO:0004872 receptor activity 439 106 64.85 1.430e-03 23 GO:0005524 ATP binding 697 131 102.96 1.520e-03 24 GO:0003729 mRNA binding 192 50 28.36 1.830e-03 25 GO:0005089 Rho guanyl-nucleotide exchange factor activity 25 10 3.69 1.880e-03 26 GO:0001191 RNA polymerase II transcription factor binding transcription factor activity involved in negative re... 5 4 0.74 2.090e-03 27 GO:0004871 signal transducer activity 469 118 69.28 2.100e-03 28 GO:0005088 Ras guanyl-nucleotide exchange factor activity 33 15 4.87 2.600e-03 29 GO:0017124 SH3 domain binding 8 5 1.18 2.650e-03 30 GO:0005125 cytokine activity 3 3 0.44 3.220e-03 31 GO:0008526 phosphatidylinositol transporter activity 3 3 0.44 3.220e-03 32 GO:0004716 receptor signaling protein tyrosine kinase activity 3 3 0.44 3.220e-03 33 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity 3 3 0.44 3.220e-03 34 GO:0070491 repressing transcription factor binding 15 7 2.22 3.270e-03 35 GO:0005057 receptor signaling protein activity 48 17 7.09 4.070e-03 36 GO:0008017 microtubule binding 64 18 9.45 4.210e-03 37 GO:0003779 actin binding 120 29 17.73 4.250e-03 38 GO:0003682 chromatin binding 80 21 11.82 5.110e-03 39 GO:0004629 phospholipase C activity 9 5 1.33 5.240e-03 40 GO:0033613 activating transcription factor binding 9 5 1.33 5.240e-03 41 GO:0008060 ARF GTPase activator activity 9 5 1.33 5.240e-03 42 GO:0008227 G-protein coupled amine receptor activity 20 8 2.95 5.340e-03 43 GO:0004995 tachykinin receptor activity 6 4 0.89 5.540e-03 44 GO:0042165 neurotransmitter binding 53 18 7.83 6.240e-03 45 GO:0046983 protein dimerization activity 135 36 19.94 6.710e-03 46 GO:0005112 Notch binding 13 6 1.92 6.940e-03 47 GO:0000976 transcription regulatory region sequence-specific DNA binding 68 31 10.04 7.040e-03 48 GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor a... 21 8 3.10 7.520e-03 49 GO:0005525 GTP binding 169 37 24.96 7.920e-03 50 GO:0016301 kinase activity 373 87 55.10 7.990e-03 51 GO:0042803 protein homodimerization activity 68 18 10.04 8.340e-03 52 GO:0019992 diacylglycerol binding 26 9 3.84 9.510e-03 53 GO:0016773 phosphotransferase activity, alcohol group as acceptor 347 82 51.26 9.840e-03 54 GO:0001653 peptide receptor activity 46 16 6.80 1.032e-02 55 GO:0008307 structural constituent of muscle 14 6 2.07 1.065e-02 56 GO:0035091 phosphatidylinositol binding 31 10 4.58 1.103e-02 57 GO:0008158 hedgehog receptor activity 7 4 1.03 1.142e-02 58 GO:0008046 axon guidance receptor activity 4 3 0.59 1.145e-02 59 GO:0001106 RNA polymerase II transcription corepressor activity 4 3 0.59 1.145e-02 60 GO:0016803 ether hydrolase activity 4 3 0.59 1.145e-02 61 GO:0015172 acidic amino acid transmembrane transporter activity 4 3 0.59 1.145e-02 62 GO:0004687 myosin light chain kinase activity 4 3 0.59 1.145e-02 63 GO:0005313 L-glutamate transmembrane transporter activity 4 3 0.59 1.145e-02 64 GO:0019202 amino acid kinase activity 4 3 0.59 1.145e-02 65 GO:0046982 protein heterodimerization activity 65 17 9.60 1.153e-02 66 GO:0005261 cation channel activity 118 27 17.43 1.201e-02 67 GO:0008092 cytoskeletal protein binding 222 56 32.79 1.237e-02 68 GO:0030594 neurotransmitter receptor activity 52 17 7.68 1.314e-02 69 GO:0003727 single-stranded RNA binding 23 8 3.40 1.381e-02 70 GO:0071813 lipoprotein particle binding 11 5 1.62 1.485e-02 71 GO:0071814 protein-lipid complex binding 11 5 1.62 1.485e-02 72 GO:0030228 lipoprotein particle receptor activity 11 5 1.62 1.485e-02 73 GO:0004428 inositol or phosphatidylinositol kinase activity 15 6 2.22 1.556e-02 74 GO:0004683 calmodulin-dependent protein kinase activity 8 4 1.18 2.020e-02 75 GO:0004887 thyroid hormone receptor activity 2 2 0.30 2.181e-02 76 GO:0004815 aspartate-tRNA ligase activity 2 2 0.30 2.181e-02 77 GO:0005113 patched binding 2 2 0.30 2.181e-02 78 GO:0015088 copper uptake transmembrane transporter activity 2 2 0.30 2.181e-02 79 GO:0008140 cAMP response element binding protein binding 2 2 0.30 2.181e-02 80 GO:0016880 acid-ammonia (or amide) ligase activity 2 2 0.30 2.181e-02 81 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2 2 0.30 2.181e-02 82 GO:0004587 ornithine-oxo-acid transaminase activity 2 2 0.30 2.181e-02 83 GO:0015183 L-aspartate transmembrane transporter activity 2 2 0.30 2.181e-02 84 GO:0015930 glutamate synthase activity 2 2 0.30 2.181e-02 85 GO:0017112 Rab guanyl-nucleotide exchange factor activity 2 2 0.30 2.181e-02 86 GO:0015501 glutamate:sodium symporter activity 2 2 0.30 2.181e-02 87 GO:0004356 glutamate-ammonia ligase activity 2 2 0.30 2.181e-02 88 GO:0030215 semaphorin receptor binding 2 2 0.30 2.181e-02 89 GO:0016211 ammonia ligase activity 2 2 0.30 2.181e-02 90 GO:0005042 netrin receptor activity 2 2 0.30 2.181e-02 91 GO:0008188 neuropeptide receptor activity 45 15 6.65 2.198e-02 92 GO:0008528 peptide receptor activity, G-protein coupled 45 15 6.65 2.198e-02 93 GO:0042923 neuropeptide binding 45 15 6.65 2.198e-02 94 GO:0030371 translation repressor activity 12 5 1.77 2.242e-02 95 GO:0015085 calcium ion transmembrane transporter activity 12 5 1.77 2.242e-02 96 GO:0019829 cation-transporting ATPase activity 30 9 4.43 2.519e-02 97 GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity 5 3 0.74 2.548e-02 98 GO:0005283 sodium:amino acid symporter activity 5 3 0.74 2.548e-02 99 GO:0005221 intracellular cyclic nucleotide activated cation channel activity 5 3 0.74 2.548e-02 100 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding 5 3 0.74 2.548e-02 101 GO:0008266 poly(U) RNA binding 5 3 0.74 2.548e-02 102 GO:0043855 cyclic nucleotide-gated ion channel activity 5 3 0.74 2.548e-02 103 GO:0042813 Wnt-activated receptor activity 5 3 0.74 2.548e-02 104 GO:0005388 calcium-transporting ATPase activity 5 3 0.74 2.548e-02 105 GO:0005375 copper ion transmembrane transporter activity 5 3 0.74 2.548e-02 106 GO:0005080 protein kinase C binding 5 3 0.74 2.548e-02 107 GO:0038024 cargo receptor activity 35 10 5.17 2.629e-02 108 GO:0051020 GTPase binding 35 10 5.17 2.629e-02 109 GO:0008374 O-acyltransferase activity 21 7 3.10 2.649e-02 110 GO:0019900 kinase binding 31 9 4.58 3.099e-02 111 GO:0008187 poly-pyrimidine tract binding 13 5 1.92 3.209e-02 112 GO:0005217 intracellular ligand-gated ion channel activity 9 4 1.33 3.217e-02 113 GO:0031625 ubiquitin protein ligase binding 9 4 1.33 3.217e-02 114 GO:0008324 cation transmembrane transporter activity 396 72 58.50 3.266e-02 115 GO:0005096 GTPase activator activity 66 19 9.75 3.410e-02 116 GO:0005262 calcium channel activity 27 8 3.99 3.649e-02 117 GO:0004842 ubiquitin-protein ligase activity 85 19 12.56 3.930e-02 118 GO:0019787 small conjugating protein ligase activity 86 19 12.70 4.373e-02 119 GO:0004016 adenylate cyclase activity 14 5 2.07 4.400e-02 120 GO:0015179 L-amino acid transmembrane transporter activity 14 5 2.07 4.400e-02 121 GO:0015238 drug transmembrane transporter activity 14 5 2.07 4.400e-02 122 GO:0017016 Ras GTPase binding 28 8 4.14 4.470e-02 123 GO:0031267 small GTPase binding 28 8 4.14 4.470e-02 124 GO:0043566 structure-specific DNA binding 33 9 4.87 4.522e-02 125 GO:0016775 phosphotransferase activity, nitrogenous group as acceptor 6 3 0.89 4.542e-02 126 GO:0001159 core promoter proximal region DNA binding 6 3 0.89 4.542e-02 127 GO:0008143 poly(A) RNA binding 6 3 0.89 4.542e-02 128 GO:0004983 neuropeptide Y receptor activity 6 3 0.89 4.542e-02 129 GO:0000987 core promoter proximal region sequence-specific DNA binding 6 3 0.89 4.542e-02 130 GO:0070717 poly-purine tract binding 6 3 0.89 4.542e-02 131 GO:0008301 DNA bending activity 6 3 0.89 4.542e-02 132 GO:0008889 glycerophosphodiester phosphodiesterase activity 6 3 0.89 4.542e-02 133 GO:0001727 lipid kinase activity 10 4 1.48 4.748e-02 Cellular Component: GO.ID Term Annotated Significant Expected elim 1 GO:0005886 plasma membrane 624 198 96.69 4.500e-16 2 GO:0005634 nucleus 1885 362 292.09 9.600e-07 3 GO:0005887 integral to plasma membrane 208 57 32.23 6.100e-06 4 GO:0016324 apical plasma membrane 33 15 5.11 4.300e-05 5 GO:0005700 polytene chromosome 116 35 17.97 4.500e-05 6 GO:0008021 synaptic vesicle 59 23 9.14 1.500e-04 7 GO:0043195 terminal button 22 11 3.41 1.600e-04 8 GO:0005938 cell cortex 97 35 15.03 2.200e-04 9 GO:0030424 axon 68 28 10.54 2.800e-04 10 GO:0031594 neuromuscular junction 32 13 4.96 5.400e-04 11 GO:0045179 apical cortex 29 12 4.49 7.200e-04 12 GO:0045180 basal cortex 7 5 1.08 1.420e-03 13 GO:0048786 presynaptic active zone 13 7 2.01 1.530e-03 14 GO:0009986 cell surface 21 9 3.25 2.510e-03 15 GO:0070732 spindle envelope 5 4 0.77 2.520e-03 16 GO:0030054 cell junction 112 37 17.35 2.520e-03 17 GO:0097060 synaptic membrane 37 13 5.73 2.600e-03 18 GO:0016328 lateral plasma membrane 11 6 1.70 3.130e-03 19 GO:0030285 integral to synaptic vesicle membrane 3 3 0.46 3.710e-03 20 GO:0044459 plasma membrane part 352 105 54.54 4.400e-03 21 GO:0005918 septate junction 23 9 3.56 5.210e-03 22 GO:0045177 apical part of cell 72 30 11.16 6.250e-03 23 GO:0005725 intercalary heterochromatin 6 4 0.93 6.620e-03 24 GO:0005925 focal adhesion 16 7 2.48 6.660e-03 25 GO:0005819 spindle 84 22 13.02 7.660e-03 26 GO:0032155 cell division site part 13 6 2.01 8.800e-03 27 GO:0031252 cell leading edge 13 6 2.01 8.800e-03 28 GO:0045171 intercellular bridge 21 8 3.25 1.003e-02 29 GO:0048471 perinuclear region of cytoplasm 34 11 5.27 1.089e-02 30 GO:0032154 cleavage furrow 10 5 1.55 1.130e-02 31 GO:0045211 postsynaptic membrane 30 10 4.65 1.194e-02 32 GO:0031224 intrinsic to membrane 1197 234 185.48 1.255e-02 33 GO:0000235 astral microtubule 4 3 0.62 1.313e-02 34 GO:0005917 nephrocyte junction 4 3 0.62 1.313e-02 35 GO:0045254 pyruvate dehydrogenase complex 4 3 0.62 1.313e-02 36 GO:0035003 subapical complex 14 6 2.17 1.341e-02 37 GO:0043235 receptor complex 35 11 5.42 1.371e-02 38 GO:0005875 microtubule associated complex 364 72 56.40 1.460e-02 39 GO:0016021 integral to membrane 1185 231 183.62 1.606e-02 40 GO:0016323 basolateral plasma membrane 39 15 6.04 1.782e-02 41 GO:0030139 endocytic vesicle 11 5 1.70 1.811e-02 42 GO:0030863 cortical cytoskeleton 11 5 1.70 1.811e-02 43 GO:0005911 cell-cell junction 69 22 10.69 1.880e-02 44 GO:0005912 adherens junction 67 21 10.38 1.956e-02 45 GO:0005856 cytoskeleton 591 117 91.58 1.996e-02 46 GO:0016327 apicolateral plasma membrane 51 18 7.90 2.086e-02 47 GO:0031982 vesicle 131 41 20.30 2.158e-02 48 GO:0070161 anchoring junction 68 21 10.54 2.308e-02 49 GO:0005768 endosome 47 13 7.28 2.316e-02 50 GO:0005876 spindle microtubule 24 8 3.72 2.365e-02 51 GO:0016010 dystrophin-associated glycoprotein complex 8 4 1.24 2.383e-02 52 GO:0045111 intermediate filament cytoskeleton 2 2 0.31 2.399e-02 53 GO:0017122 protein N-acetylglucosaminyltransferase complex 2 2 0.31 2.399e-02 54 GO:0016013 syntrophin complex 2 2 0.31 2.399e-02 55 GO:0001726 ruffle 2 2 0.31 2.399e-02 56 GO:0005882 intermediate filament 2 2 0.31 2.399e-02 57 GO:0005638 lamin filament 2 2 0.31 2.399e-02 58 GO:0000300 peripheral to membrane of membrane fraction 2 2 0.31 2.399e-02 59 GO:0031213 RSF complex 2 2 0.31 2.399e-02 60 GO:0045172 germline ring canal 20 7 3.10 2.572e-02 61 GO:0005940 septin ring 5 3 0.77 2.905e-02 62 GO:0008623 chromatin accessibility complex 5 3 0.77 2.905e-02 63 GO:0030864 cortical actin cytoskeleton 5 3 0.77 2.905e-02 64 GO:0016028 rhabdomere 30 9 4.65 3.329e-02 65 GO:0005881 cytoplasmic microtubule 9 4 1.39 3.772e-02 66 GO:0042734 presynaptic membrane 9 4 1.39 3.772e-02 67 GO:0031410 cytoplasmic vesicle 120 38 18.59 3.900e-02 68 GO:0034702 ion channel complex 46 12 7.13 4.361e-02 69 GO:0008023 transcription elongation factor complex 27 8 4.18 4.676e-02 70 GO:0031965 nuclear membrane 18 6 2.79 4.796e-02 71 GO:0045202 synapse 150 55 23.24 4.832e-02 72 GO:0005623 cell 6501 1093 1007.35 4.943e-02 73 GO:0044464 cell part 6501 1093 1007.35 4.943e-02