CLUSTAL X (1.81) multiple sequence alignment


sp_Q61147_CERU_MOUSECeruloplas      -------------------MKFLLLSTFIFLYSS-LALARDKHYFIGITE
sp_P00450_CERU_HUMANCeruloplas      -------------------MKILILGIFLFLCST-PAWAKEKHYYIGIIE
tr_Q7ZU12Cpprotein_Brachydanio      -------------------MKGLQFALLWVLCCAGIASSITREYFFAIKE
tr_Q9BQS7Hephaestin_Homosapien      ----------------MESGHLLWALLFMQSLWPQLTDGATRVYYLGIRD
tr_Q9Z0Z4Hephaestin_Musmusculu      ----------------MKAGHLLWALLLMHSLWSIPTDGAIRNYYLGIQD
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      -------------MQIELSTCFFLCLLRFC-------FSATRRYYLGAVE
tr_Q7TN96FactorVIII_Rattusnorv      -------------MRAARGLCFFLSLCALC-------SCATRKYYLGAVE
sp_P12263_FA8_PIGCoagulationfa      -------------MQLELSTCVFLCLLPLG-------FSAIRRYYLGAVE
tr_O62730FactorVIII_Canisfamil      -------------MQVELYTCCFLCLLPFS-------LSATRKYYLGAVE
tr_Q804W6CoagulationfactorVIII      --------MRTDTLLLPLPLPLLLLVAAFCGGDAQQPPAAVRQYYIAAVE
sp_Q06194_FA8_MOUSECoagulation      -------------MQIALFACFFLSLFNFC-------SSAIRRYYLGAVE
tr_Q7TPK2Ac2_120_Rattusnorvegi      MQSSEGQVQEKQAEIRRSDKNHVGAFLYVPLYVFHDLEYKQFQTYPSLGL
tr_O88783Murinecoagulationfact      ------------------------MLLVCPCFFLLVVLGTRWAGWGSHQA
sp_Q28107_FA5_BOVINCoagulation      ------------------------MFLACPGFWVLVVLGSSWAGWGNLGA
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      ------------------------MFPALPCPWVLVVLGTSWAAWGNLGT
sp_P12259_FA5_HUMANCoagulation      ------------------------MFPGCPRLWVLVVLGTSWVGWGSQGT
tr_Q7SZN0PseutarinCprecursor_P      ----------------------MGRYSVSPVPKCLLLMFLGWSGLKYYQV
tr_Q804W5CoagulationfactorVpre      --------------------------------------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      ----------------------------MKLRSWPGALHGLALLAFLCHC
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      AVWDYASGTE--EKKLISVDTEQSNFYLQNGPDRIGRKYKKALYFEYTDG
sp_P00450_CERU_HUMANCeruloplas      TTWDYASDHG--EKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDE
tr_Q7ZU12Cpprotein_Brachydanio      IQWDYAPSGKNLIQNKTVQQDEAARVFLERGEQRIGRVYKKAVYHQYTDA
tr_Q9BQS7Hephaestin_Homosapien      VQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYKEYKDD
tr_Q9Z0Z4Hephaestin_Musmusculu      MQWNYAPKGRNVITNQTLNNDTVASSFLKSGKNRIGSSYKKTVYKEYSDG
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      LSWDYMQSDLG-ELPVDARFPPRVPKSFPFNTS---VVYKKTLFVEFTDH
tr_Q7TN96FactorVIII_Rattusnorv      LPWDYVSGGASGAQRSDSRFPPGTP---APSAH---VVHTKTVFVEYMDR
sp_P12263_FA8_PIGCoagulationfa      LSWDYRQSELLRELHVDTRFPATAPGALPLGPS---VLYKKTVFVEFTDQ
tr_O62730FactorVIII_Canisfamil      LSWDYMQSDLLSALHADTSFSSRVPGSLPLTTS---VTYRKTVFVEFTDD
tr_Q804W6CoagulationfactorVIII      IGWDY--------IHVEDGDPASEQRKKPKDIP---QKYIKAVYREYLDA
sp_Q06194_FA8_MOUSECoagulation      LSWNYIQSDLLSVLHTDSRFLPRMSTSFPFNTS---IMYKKTVFVEYKDQ
tr_Q7TPK2Ac2_120_Rattusnorvegi      LGPTLYAEVGDTIKVHFRNKADKPLSIHPQ-GIRYSKFSEAQLFAEEEMD
tr_O88783Murinecoagulationfact      EAAQLRQFYVAAQGILWN---YHPEPTDPS-LNSIP-SFKKIVYREYEQY
sp_Q28107_FA5_BOVINCoagulation      EAAKLRQFYVAAQSIRWN---YRPESTHLS-SKPFETSFKKIVYREYEAY
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      EAARVRQFYVAAQSISWN---YHPEPTHPS-SSPFATSFKKIVYREYEAY
sp_P12259_FA5_HUMANCoagulation      EAAQLRQFYVAAQGISWS---YRPEPTNSS-LNLSVTSFKKIVYREYEPY
tr_Q7SZN0PseutarinCprecursor_P      NAAQLREYHIAAQLEDWD---YNPQPEELSRLSESDLTFKKIVYREYELD
tr_Q804W5CoagulationfactorVpre      ----------------------------------FSPTYKKVVFREYDKD
tr_Q90X47SC_bZ20I5.3_Novelprot      ATAVERHYYIAAVNINWD---------YTSGQQRTGQSYKKVVYREYNEG
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      TFS-------------------KTIDKPAWLGFLGPVIKAEVEDKVYVHL
sp_P00450_CERU_HUMANCeruloplas      TFR-------------------TTIEKPVWLGFLGPIIKAETGDKVYVHL
tr_Q7ZU12Cpprotein_Brachydanio      TYR-------------------QEIDKPKWLGYLGPLISAEEDDTVIVHL
tr_Q9BQS7Hephaestin_Homosapien      SYT-------------------DEVAQPAWLGFLGPVLQAEVGDVILIHL
tr_Q9Z0Z4Hephaestin_Musmusculu      TYT-------------------EEIAKPAWLGFLGPLLQAEVGDVILIHL
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      LFN-------------------IAKPRPPWMGLLGPTIQAEVYDTVVITL
tr_Q7TN96FactorVIII_Rattusnorv      FFH-------------------TAKPRPLWMGLLGPTIWTEVHDTVVITL
sp_P12263_FA8_PIGCoagulationfa      LFS-------------------VARPRPPWMGLLGPTIQAEVYDTVVVTL
tr_O62730FactorVIII_Canisfamil      LFN-------------------IAKPRPPWMGLLGPTIQAEVYDTVVIVL
tr_Q804W6CoagulationfactorVIII      TYT-------------------VPKPRPAWTGIQGPVIVAQAGETVLVHF
sp_Q06194_FA8_MOUSECoagulation      LFN-------------------IAKPRPPWMGLLGPTIWTEVHDTVVITL
tr_Q7TPK2Ac2_120_Rattusnorvegi      FAAPFILLRCLFDPPSLSQQALVLLPKRKTGFYVTPLLLEGVPGVHRLSM
tr_O88783Murinecoagulationfact      FKK--------------------EKPRSSNSGLLGPTLYAEVGDVIKVHF
sp_Q28107_FA5_BOVINCoagulation      FQK--------------------EKPQSRTSGLLGPTLYAEVGDIMKVHF
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      FQK--------------------EKPPSRMSGLLGPTLYADVGDIMKVHF
sp_P12259_FA5_HUMANCoagulation      FKK--------------------EKPQSTISGLLGPTLYAEVGDIIKVHF
tr_Q7SZN0PseutarinCprecursor_P      FKQ--------------------EEPRDALSGLLGPTLRGEVGDSLIIYF
tr_Q804W5CoagulationfactorVpre      FKQ--------------------PKSRPPWLGLLGPTLRAEEGEIIVVTF
tr_Q90X47SC_bZ20I5.3_Novelprot      FKQ--------------------PKAHPLSSGLLGPTLRGQEGDTIIVTF
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      KNLASRI--------------YTFHAHG----------------------
sp_P00450_CERU_HUMANCeruloplas      KNLASRP--------------YTFHSHG----------------------
tr_Q7ZU12Cpprotein_Brachydanio      KNMARRA--------------YSLHAHG----------------------
tr_Q9BQS7Hephaestin_Homosapien      KNFATRP--------------YTIHPHG----------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      KNFASRP--------------YTIHPHG----------------------
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      KNMASHP--------------VSLHAVG----------------------
tr_Q7TN96FactorVIII_Rattusnorv      KNMASHP--------------VSLHAVG----------------------
sp_P12263_FA8_PIGCoagulationfa      KNMASHP--------------VSLHAVG----------------------
tr_O62730FactorVIII_Canisfamil      KNMASHP--------------VSLHAVG----------------------
tr_Q804W6CoagulationfactorVIII      KNLASQP--------------YSISPVG----------------------
sp_Q06194_FA8_MOUSECoagulation      KNMASHP--------------VSLHAVG----------------------
tr_Q7TPK2Ac2_120_Rattusnorvegi      GLYTMKRGIFTLGQTGFMCPRSRLHAGAGCGDRRGGEEPERASASPFLHT
tr_O88783Murinecoagulationfact      RNKADKP--------------LSIHPQG----------------------
sp_Q28107_FA5_BOVINCoagulation      KNKAHKP--------------LSIHAQG----------------------
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      RNKADKP--------------LSIHPQG----------------------
sp_P12259_FA5_HUMANCoagulation      KNKADKP--------------LSIHPQG----------------------
tr_Q7SZN0PseutarinCprecursor_P      KNFATQP--------------VSIHPQS----------------------
tr_Q804W5CoagulationfactorVpre      RNLATKP--------------YSIHPHG----------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      RNMADHP--------------CSLHPHG----------------------
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------VTYTKEYEGAVYPDNTTDFQRADDKVLPGQQYVYVLHANE-P
sp_P00450_CERU_HUMANCeruloplas      --------ITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQ
tr_Q7ZU12Cpprotein_Brachydanio      --------LSYNKTNEGALYPDSSEKVEKHDDSVAPGTTFTYIWTLPASH
tr_Q9BQS7Hephaestin_Homosapien      --------VFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGH
tr_Q9Z0Z4Hephaestin_Musmusculu      --------VFYEKDSEGSLYPDGSSGYLKADDSVPPGGSHVYNWSIPESH
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      --------VSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKEN
tr_Q7TN96FactorVIII_Rattusnorv      --------MSFWKASEGAAYDDHSSPAEKDDDKVLPGESHTYAWQVLGES
sp_P12263_FA8_PIGCoagulationfa      --------VSFWKSSEGAEYEDHTSQREKEDDKVLPGKSQTYVWQVLKEN
tr_O62730FactorVIII_Canisfamil      --------VSYWKASEGAEYEDQTSQKEKEDDNVIPGESHTYVWQVLKEN
tr_Q804W6CoagulationfactorVIII      --------ISYWKHSEGAGYDDSTAGHEKEDDAVYPGGYYEYVWDISPKD
sp_Q06194_FA8_MOUSECoagulation      --------VSYWKASEGDEYEDQTSQMEKEDDKVFPGESHTYVWQVLKEN
tr_Q7TPK2Ac2_120_Rattusnorvegi      GEWWKTLDVFVAVTSPGASYLDHTSPAERKDDAVAAGEEYTYEWFIGEDS
tr_O88783Murinecoagulationfact      --------IKYSKFSEGASYADHTFPAERKDDAVAPGEEYTYEWIVSEDS
sp_Q28107_FA5_BOVINCoagulation      --------IKYSKFSEGASYSDHTLPMEKMDDAVAPGQEYTYEWIISEHS
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      --------IKYSKFAEGASYPDHTFLVEKMDDAVAPGQEYTYEWNISEDS
sp_P12259_FA5_HUMANCoagulation      --------IRYSKLSEGASYLDHTFPAEKMDDAVAPGREYTYEWSISEDS
tr_Q7SZN0PseutarinCprecursor_P      --------AVYNKWSEGSSYSDGTSDVERLDDAVPPGQSFKYVWNITAEI
tr_Q804W5CoagulationfactorVpre      --------VAYGKQSEGANYFDNTSQKEKEDDVVWPNSEHVYYWEITSDV
tr_Q90X47SC_bZ20I5.3_Novelprot      --------IAYGKQSEGSLYFDNTSLLEKNDDVIQPGEEHTYQWDVTSDV
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      SPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLYKE---KEKN
sp_P00450_CERU_HUMANCeruloplas      SPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKE---KEKH
tr_Q7ZU12Cpprotein_Brachydanio      APGKDDTNCLTRIYHSHVNAPKDIASGLIGPLIVCKKGSLDVH---GDKT
tr_Q9BQS7Hephaestin_Homosapien      APTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQD
tr_Q9Z0Z4Hephaestin_Musmusculu      APTEADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGTLDGNSPPQRKD
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      GPMASDPLCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLAKE----KTQ
tr_Q7TN96FactorVIII_Rattusnorv      GPMASDPPCLTYAYLSHVDLVRDLNSGLVGALLVCKEGRLSAE----RTR
sp_P12263_FA8_PIGCoagulationfa      GPTASDPPCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLTRE----RTQ
tr_O62730FactorVIII_Canisfamil      GPMASDPPCLTYSYFSHVDLVKDLNSGLIGALLVCKEGSLAKE----RTQ
tr_Q804W6CoagulationfactorVIII      GPTGSDPECLTYSYSSQVDPVRDVNSGLIGALLICKMSAFTDE----GQR
sp_Q06194_FA8_MOUSECoagulation      GPMASDPPCLTYSYMSHVDLVKDLNSGLIGALLVCKEGSLSKE----RTQ
tr_Q7TPK2Ac2_120_Rattusnorvegi      GPTPDDPPCLTHIYYSYENLTQDFNSGLIGPLLICKEGTLTEDG--TQKM
tr_O88783Murinecoagulationfact      GPTPDDPPCLTHIYYSYENLTQDFNSGLIGPLLICKKGTLTEDG--TQKM
sp_Q28107_FA5_BOVINCoagulation      GPTHDDPPCLTHIYYSYVNLVEDFNSGLIGPLLICKKGTLTEDG--TQKM
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      GPTHNDPPCLTHIYYSYENLIQDFNSGLIGPLLICKKGTLTEDG--IQKM
sp_P12259_FA5_HUMANCoagulation      GPTHDDPPCLTHIYYSHENLIEDFNSGLIGPLLICKKGTLTEGG--TQKT
tr_Q7SZN0PseutarinCprecursor_P      GPKKADPPCLTYAYYSHVNMVRDFNSGLIGALLICKEGSLNANG--SQKF
tr_Q804W5CoagulationfactorVpre      SPQQNDPTCLTYTYISHKDVVEDYNSGLIGALLVCKSGSLDESG--RQIG
tr_Q90X47SC_bZ20I5.3_Novelprot      TPTAADPPCITYTYLSHFDIVRDYNTGLIGPMLICKKGTLDDSG--NQIH
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      IDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSI
sp_P00450_CERU_HUMANCeruloplas      IDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESNRMYSV
tr_Q7ZU12Cpprotein_Brachydanio      GDYLYTLMFTVSDENLSWYLDENIKTYCSAPAKVNKDDEAFQESNKMHSI
tr_Q9BQS7Hephaestin_Homosapien      TDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAI
tr_Q9Z0Z4Hephaestin_Musmusculu      VDHNFFLLFSVIDENLSWHLDDNIATYCSDPASVDKEDGAFQDSNRMHAI
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      TLHKFILLFAVFDEGKSWHSETKNSLMQDRDAASARAW------PKMHTV
tr_Q7TN96FactorVIII_Rattusnorv      MPPHFVLLFAVFDEGRSWHAATR-------DPASTEAQ------PTVHTV
sp_P12263_FA8_PIGCoagulationfa      NLHEFVLLFAVFDEGKSWHSARNDSWTRAMDPAPARAQ------PAMHTV
tr_O62730FactorVIII_Canisfamil      TLQEFVLLFAVFDEGKSWHSETNASLT------QAEAQ------HELHTI
tr_Q804W6CoagulationfactorVIII      RNQAFVLLFVVFDESKSWYGEVGERKSRD-KFKRSDSR------KEFHTI
sp_Q06194_FA8_MOUSECoagulation      MLYQFVLLFAVFDEGKSWHSETNDSYTQSMDSASARDW------PKMHTV
tr_Q7TPK2Ac2_120_Rattusnorvegi      FDKQHVLLFAVFDESKSWSQSPA----------------------LMYTV
tr_O88783Murinecoagulationfact      FDKQHVLLFAVFDESKSRSQSPS----------------------LMYTI
sp_Q28107_FA5_BOVINCoagulation      FEKQHVLMFAVFDESKSWNQTSS----------------------LMYTV
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      FDKQYVLMFAVFDESKSWNQSSS----------------------LMYTV
sp_P12259_FA5_HUMANCoagulation      FDKQIVLLFAVFDESKSWSQSSS----------------------LMYTV
tr_Q7SZN0PseutarinCprecursor_P      FNREYVLMFSVFDESKNWYRKPS----------------------LQYTI
tr_Q804W5CoagulationfactorVpre      IYHEYVFLFGVFNENESKFKQNDPASVDH----------------IKYTI
tr_Q90X47SC_bZ20I5.3_Novelprot      FHQESVLLFGVFDENKSWYSTGDSPQPLN----------------VKYTI
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      NGYTFGSLPGLSMCAADR-VKWYLFGMGNEVDVHSAFFHGQALTSRNYQT
sp_P00450_CERU_HUMANCeruloplas      NGYTFGSLPGLSMCAEDR-VKWYLFGMGNEVDVHAAFFHGQALTNKNYRI
tr_Q7ZU12Cpprotein_Brachydanio      NGYVYGNLPDLSMCMGNK-IHWHLFGMGNEVDIHSAFFHGQILTDKRQHV
tr_Q9BQS7Hephaestin_Homosapien      NGFVFGNLPELNMCAQKR-VAWHLFGMGNEIDVHTAFFHGQMLTTRGHHT
tr_Q9Z0Z4Hephaestin_Musmusculu      NGFVFGNLPELSMCAQKH-VAWHLFGMGNEIDVHTAFFHGQMLSIRGHHT
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      NGYVNRSLPGLIGCHRKS-VYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQ
tr_Q7TN96FactorVIII_Rattusnorv      NGYTNRTLPGLTGCRGTS-VYWHVMAVGTTPDIHSILLEGHTFSVRSHRQ
sp_P12263_FA8_PIGCoagulationfa      NGYVNRSLPGLIGCHKKS-VYWHVIGMGTSPEVHSIFLEGHTFLVRHHRQ
tr_O62730FactorVIII_Canisfamil      NGYVNRSLPGLTVCHKRS-VYWHVIGMGTTPEVHSIFLEGHTFLVGNHRQ
tr_Q804W6CoagulationfactorVIII      NGYINATLPGLKICQGRNPVIWHLIGMGTAPAIHLIQFQHHTLEVLTHRK
sp_Q06194_FA8_MOUSECoagulation      NGYVNRSLPGLIGCHRKS-VYWHVIGMGTTPEIHSIFLEGHTFFVRNHRQ
tr_Q7TPK2Ac2_120_Rattusnorvegi      NGFVNRTMPDVTVCAYDH-VSWHLIGMSSGPELFSIHFNGQVLEQNQHKV
tr_O88783Murinecoagulationfact      NGFVNKTMPDITVCAHDH-VSWHLIGMSSGPELFSIHFNGQVLEQNQHKV
sp_Q28107_FA5_BOVINCoagulation      NGYVNGTMPDITVCAHDH-ISWHLIGMSSGPELFSIHFNGQVLEQNHHKI
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      NGYVNGTMPDITVCAYDH-ISWHLIGMSSGPELFSIHFSGQVLEQNHHKV
sp_P12259_FA5_HUMANCoagulation      NGYVNGTMPDITVCAHDH-ISWHLLGMSSGPELFSIHFNGQVLEQNHHKV
tr_Q7SZN0PseutarinCprecursor_P      NGFANGTLPDVQACAYDH-ISWHLIGMSSSPEIFSVHFNGQTLEQNHYKV
tr_Q804W5CoagulationfactorVpre      NGFTEGSLPDVSICTYAP-VSLHLVGMSSDPEVFSVHINGQVLQQNGHKM
tr_Q90X47SC_bZ20I5.3_Novelprot      NGYTNGSVPDLDICAHSK-VSWHLLGMSSEPELFSVHFNGQVLLHDGHKT
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      DIINLFPATLIDAYMVAQNPGVWMLSC-----QNLNHLKAG-LQAFFQVQ
sp_P00450_CERU_HUMANCeruloplas      DTINLFPATLFDAYMVAQNPGEWMLSC-----QNLNHLKAG-LQAFFQVQ
tr_Q7ZU12Cpprotein_Brachydanio      DTVSLFPATFVNVEMVADNPGQWLLSC-----QVNDHLEAG-MQAFFEIK
tr_Q9BQS7Hephaestin_Homosapien      DVANIFPATFVTAEMVPWEPGTWLISC-----QVNSHFRDG-MQALYKVK
tr_Q9Z0Z4Hephaestin_Musmusculu      DVANIFPATFVTAEMVPQKSGTWLISC-----EVNSHLRSG-MQAFYKVD
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      ASLEISPITFLTAQTLLMDLGQFLLFC-----HISSHQHDG-MEAYVKVD
tr_Q7TN96FactorVIII_Rattusnorv      ASLEISPMTLLTAQTWLMDLGRFLLFC-----HISSHRHGG-MEAYVQVD
sp_P12263_FA8_PIGCoagulationfa      ASLEISPLTFLTAQTFLMDLGQFLLFC-----HISSHHHGG-MEAHVRVE
tr_O62730FactorVIII_Canisfamil      ASLEISPITFLTAQTFLMDLGQFLLFC-----HIPSHQHDG-MEAYVKVD
tr_Q804W6CoagulationfactorVIII      VTVEVTPMTFVTAEMKPATVGSFLISC-----QIHAPRHDG-MSAMFLVE
sp_Q06194_FA8_MOUSECoagulation      ASLEISPITFLTAQTLLIDLGQFLLFC-----HISSHKHDG-MEAYVKVD
tr_Q7TPK2Ac2_120_Rattusnorvegi      STVTLLQTVGIFIRPIALNTVQGYIASRGEDLLVPWATRAAGMQAYIDIK
tr_O88783Murinecoagulationfact      STVTLVSATSTTANMTMSPEGRWIVSS-----LIPKHYQAG-MQAYIDIK
sp_Q28107_FA5_BOVINCoagulation      SAITLVSATSTTANMTVSPEGRWTIAS-----LIPRHFQAG-MQAYIDIK
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      SAITLVSATSTTANMTVSPEGKWPISS-----LIPKHFQAG-MQAYIDIK
sp_P12259_FA5_HUMANCoagulation      SAITLVSATSTTANMTVGPEGKWIISS-----LTPKHLQAG-MQAYIDIK
tr_Q7SZN0PseutarinCprecursor_P      STINLVGGASVTADMSVSRTGKWLISS-----LVAKHLQAG-MYGYLNIK
tr_Q804W5CoagulationfactorVpre      SSVGLISGSSTTVSMVAVHTGRWLLSS-----QIMKHIQGK-MYGFVNME
tr_Q90X47SC_bZ20I5.3_Novelprot      SAVGIISGTATSASMTGVHPGRWLVSS-----HISKHLEAG-LHGYLNIR
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      DCNKPSSKD-----------------------------------NIRGKH
sp_P00450_CERU_HUMANCeruloplas      ECNKSSSKD-----------------------------------NIRGKH
tr_Q7ZU12Cpprotein_Brachydanio      KCFPNVHKP-----------------------------------RPFG-E
tr_Q9BQS7Hephaestin_Homosapien      SCSMAPPVD-----------------------------------LLTG-K
tr_Q9Z0Z4Hephaestin_Musmusculu      SCSMDPPVD-----------------------------------QLTG-K
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      SCPEEPQLR----MKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRS
tr_Q7TN96FactorVIII_Rattusnorv      NCPEAPQGQ----GKRDEDTEDYDD--LDSEMDVFTWDP-DAAPFVQVRS
sp_P12263_FA8_PIGCoagulationfa      SCAEEPQLR----RKAD-EEEDYDDNLYDSDMDVVRLDGDDVSPFIQIRS
tr_O62730FactorVIII_Canisfamil      SCPEEPQLR----MKNN-EDKDYDDGLYGSDMDVVSFDDDSSSPFIQIRS
tr_Q804W6CoagulationfactorVIII      KCPDPVVLPGPDMRNAKPSNDDDYDYNYDGEEMFNIINFKPKELKPQVRS
sp_Q06194_FA8_MOUSECoagulation      SCPEESQWQ----KKNNNEEMEDYDDDLYSEMDMFTLDYDSSP-FIQIRS
tr_Q7TPK2Ac2_120_Rattusnorvegi      NCPKKTRSS------------------------------------KTLTR
tr_O88783Murinecoagulationfact      NCPKKTRSP------------------------------------KTLTR
sp_Q28107_FA5_BOVINCoagulation      NCAKKTRNP------------------------------------KKLTR
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      NCAKKTRKP------------------------------------KKLTR
sp_P12259_FA5_HUMANCoagulation      NCPKKTRNL------------------------------------KKITR
tr_Q7SZN0PseutarinCprecursor_P      DCGNPDTLT------------------------------------RKLSF
tr_Q804W5CoagulationfactorVpre      ICDGFKAPQ------------------------------------RTLTR
tr_Q90X47SC_bZ20I5.3_Novelprot      KCDEYTAPK------------------------------------RRLTI
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      VRHYYIAAEEVIWNYAPSGIDIFTEEKLTASGSDSGVFFEQGATRIGGSY
sp_P00450_CERU_HUMANCeruloplas      VRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSY
tr_Q7ZU12Cpprotein_Brachydanio      VRQYYIAAEEIIWDYGPTEINQYTMKKLVD-DIVSDTFFDNRNDRIGGKY
tr_Q9BQS7Hephaestin_Homosapien      VRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTY
tr_Q9Z0Z4Hephaestin_Musmusculu      VRQYFIQAHEIQWDYGPIGYDGRTGKSLREPGSGPDKYFQKSSSRIGGTY
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      VAKKHPKTWVHYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKY
tr_Q7TN96FactorVIII_Rattusnorv      AAKRHPKTWVHYIAAEEGDWDYAPAAATLEDGSLRNRYLGRGPGRIGSKY
sp_P12263_FA8_PIGCoagulationfa      VAKKHPKTWVHYISAEEEDWDYAPAVPSPSDRSYKSLYLNSGPQRIGRKY
tr_O62730FactorVIII_Canisfamil      VAKKHPKTWVHYIAAEEEDWDYAPSGPTPNDRSHKNLYLNNGPQRIGKKY
tr_Q804W6CoagulationfactorVIII      SRGANFQVWEHYIAIEELTWDYTP-HLSSTDSELQSRFFPTSASRLSYKY
sp_Q06194_FA8_MOUSECoagulation      VAKKYPKTWIHYISAEEEDWDYAPSVPTSDNGSYKSQYLSNGPHRIGRKY
tr_Q7TPK2Ac2_120_Rattusnorvegi      EQRRHMKRWEYFIAAEEVIWNYAPVIPANMDK------------------
tr_O88783Murinecoagulationfact      EQRRYMKRWEYFIAAEEVIWNYAPVIPANMDKIYRSQHLDNFSNQIGKHY
sp_Q28107_FA5_BOVINCoagulation      DQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNRIGKHY
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      DQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNQIGKHY
sp_P12259_FA5_HUMANCoagulation      EQRRHMKRWEYFIAAEEVIWDYAPVIPANMDKKYRSQHLDNFSNQIGKHY
tr_Q7SZN0PseutarinCprecursor_P      RELMKIKNWEYFIAAEEITWDYAPEIPSSVDRRYKAQYLDNFSNFIGKKY
tr_Q804W5CoagulationfactorVpre      EQRKNSREWTYYIAAEEIVWNYAPNEPAHIDQDYKLQYLRQSSTRIGGKY
tr_Q90X47SC_bZ20I5.3_Novelprot      EQKKESQEWTYYMAAEEVIWDYAPNMPENMDGDFRSKYLKQGPQRIGKKY
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      KKMAYREYTDGSFTNRKERGPDEEHLGILGPVIWAEVGDTIKVTFHNKGQ
sp_P00450_CERU_HUMANCeruloplas      KKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGA
tr_Q7ZU12Cpprotein_Brachydanio      KKVQYVEYTDDTFTKRKEKTPEEQHLGILGPVIRAEEEDTIKVTFRNKAS
tr_Q9BQS7Hephaestin_Homosapien      WKVRYEAFQDETFQEKMHL-EEDRHLGILGPVIRAEVGDTIQVVFYNRAS
tr_Q9Z0Z4Hephaestin_Musmusculu      WKVRYEAFQDETFQERVHQ-EEETHLGILGPVIRAEVGDTIQVVFYNRAS
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      KKVRFMAYTDETFK---TREAIQHESGILGPLLYGEVGDTLLIIFKNQAS
tr_Q7TN96FactorVIII_Rattusnorv      KKVRFVAYTDGTFH---TREATPREAGLLGPLLYGEVGDSLLIVFKNRAS
sp_P12263_FA8_PIGCoagulationfa      KKARFVAYTDVTFK---TRKAIPYESGILGPLLYGEVGDTLLIIFKNKAS
tr_O62730FactorVIII_Canisfamil      KKVRFVAYTDETFK---TREAIQYESGILGPLLYGEVGDTLLIIFKKQAS
tr_Q804W6CoagulationfactorVIII      KKVAFVEYTDKSFT---RRK--NTEKSLMGPLLKGKVGDQIHIMLKNTAS
sp_Q06194_FA8_MOUSECoagulation      KKVRFIAYTDETFK---TRETIQHESGLLGPLLYGEVGDTLLIIFKNQAS
tr_Q7TPK2Ac2_120_Rattusnorvegi      --------------------------------------------------
tr_O88783Murinecoagulationfact      KKVIYRQYEEETFTKRTDNPSIK-QSGILGPVIRAQVRDTLKIVFKNMAS
sp_Q28107_FA5_BOVINCoagulation      KKVVYKQYQDDSFTKRLEDPSSE-GDGILGPIIRAQVRDTLKIVFKNMAS
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      KKVVYKQYQDESFTKRLENPNNK-EDGILGPVIRAQVRDTLKIVFKNMAS
sp_P12259_FA5_HUMANCoagulation      KKVMYTQYEDESFTKHTVNPNMK-EDGILGPIIRAQVRDTLKIVFKNMAS
tr_Q7SZN0PseutarinCprecursor_P      KKAVFRQYEDGNFTKPTYAIWPK-ERGILGPVIKAKVRDTVTIVFKNLAS
tr_Q804W5CoagulationfactorVpre      KKAVYTLYTNESFTEQVHKKQRKDELGILGPVIRAQIRDVIKIVFKNKAT
tr_Q90X47SC_bZ20I5.3_Novelprot      KKAVFTQYKDGMFKERAEDKQRKRELGILGPVIRAQIRDIIKIVFKNKAS
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      HHLSIQPMGVSFTAENEGTYYGP-----------------PGASSQQAAS
sp_P00450_CERU_HUMANCeruloplas      YPLSIEPIGVRFNKNNEGTYYSPNYNP-------------QSRSVPPSAS
tr_Q7ZU12Cpprotein_Brachydanio      RPFSIQPHGVQYNIDMDGTLYHNVLEESYTDKKLRELKKQPRVIEPLPAA
tr_Q9BQS7Hephaestin_Homosapien      QPFSMQPHGVFYEKDYEGTVYND--------------------GSSYPGL
tr_Q9Z0Z4Hephaestin_Musmusculu      QPFSIQPHGVFYEKNSEGTVYND--------------------GTSHP-K
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      RPYNIYPHGITDVRPLYSRRLPKGVKHLK-------------------DF
tr_Q7TN96FactorVIII_Rattusnorv      RAYNIHPHGIRDVGAVHAGRLPRGVKHVK-------------------DL
sp_P12263_FA8_PIGCoagulationfa      RPYNIYPHGITDVSALHPGRLLKGWKHLK-------------------DM
tr_O62730FactorVIII_Canisfamil      RPYNIYPHGINYVTPLHTGRLPKGVKHLK-------------------DM
tr_Q804W6CoagulationfactorVIII      RPFNIYPNGLSSIRPMKRSKNAS-EKDLR-------------------TM
sp_Q06194_FA8_MOUSECoagulation      RPYNIYPHGITDVSPLHARRLPRGIKHVK-------------------DL
tr_Q7TPK2Ac2_120_Rattusnorvegi      -------HSYPLSPMGMWPDDSNRNN-GS-----------------RMLA
tr_O88783Murinecoagulationfact      RPYSIYPHGVTFSPYEDGINSSSTSG-SH-----------------TTIR
sp_Q28107_FA5_BOVINCoagulation      RSYSIYPHGVTFSPYDNEVNSSSTSG-SN-----------------TMIR
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      RSYSIYPHGVTFSPYEDDVNSSSTSD-NN-----------------TMIR
sp_P12259_FA5_HUMANCoagulation      RPYSIYPHGVTFSPYEDEVNSSFTSGRNN-----------------TMIR
tr_Q7SZN0PseutarinCprecursor_P      RPYSIYVHGVSVSKDAEGAIYPSDPKENI-----------------THGK
tr_Q804W5CoagulationfactorVpre      RPYSIYPHGLTIEKSEEGVNYPPGSN---------------------HSH
tr_Q90X47SC_bZ20I5.3_Novelprot      RPYSIYPHGLTIDKAAEGASYPQGGN---------------------QTY
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      HVAPKXTFTYEWTVPKEMGPTYADPVCLSKMYYSAVDPTKDIFTGLIGPM
sp_P00450_CERU_HUMANCeruloplas      HVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFTGLIGPM
tr_Q7ZU12Cpprotein_Brachydanio      MVRPDTTYKYEWVVPKDGGPTEKDPDCLTYLYYSAVDPIRDTNSGLVGPL
tr_Q9BQS7Hephaestin_Homosapien      VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPL
tr_Q9Z0Z4Hephaestin_Musmusculu      VAKSFEKVTYYWTVPPHAGPTAQDPACLTWMYFSAADPTRDTNSGLVGPL
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      PILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPL
tr_Q7TN96FactorVIII_Rattusnorv      PIRPGETFKYRWTLTAEDGPARSDARCVTRYYASAVDPERDLASGLIGPL
sp_P12263_FA8_PIGCoagulationfa      PILPGETFKYKWTVTVEDGPTKSDPRCLTRYYSSSINLEKDLASGLIGPL
tr_O62730FactorVIII_Canisfamil      PILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINLERDLASGLIGPL
tr_Q804W6CoagulationfactorVIII      GVGPNETFGYMWELTANDRPLEEDPQCLTQLYQSTVDPEKDLASGLVGTL
sp_Q06194_FA8_MOUSECoagulation      PIHPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINPERDLASGLIGPL
tr_Q7TPK2Ac2_120_Rattusnorvegi      TVNP-----CSRCLLRLSHQFYKLGAILVFLYLREGARK-----------
tr_O88783Murinecoagulationfact      PVQPGETFTYKWNILEFDEPTENDAQCLTRPYYSDVDVTRDIASGLIGLL
sp_Q28107_FA5_BOVINCoagulation      AVRPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDLASGLIGLL
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      AVQPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDIASGLIGLL
sp_P12259_FA5_HUMANCoagulation      AVQPGETYTYKWNILEFDEPTENDAQCLTRPYYSDVDIMRDIASGLIGLL
tr_Q7SZN0PseutarinCprecursor_P      AVEPGQVYTYKWTVLDTDEPTVKDSECITKLYHSAVDMTRDIASGLIGPL
tr_Q804W5CoagulationfactorVpre      SVQPGETHTYTWKVVEEDEPLDDDARCLTRLYHSAVDTPRDIASGLIGPL
tr_Q90X47SC_bZ20I5.3_Novelprot      SVQPGETYTYTWSVTEEDVPTDSDPRCLTRMYHSAVDAPRDIASGLVGPL
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      KICKKGSLLADGRQKDVDKEFYLFPTVFDENESLLLDDNIRMFTHAPDQV
sp_P00450_CERU_HUMANCeruloplas      KICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQV
tr_Q7ZU12Cpprotein_Brachydanio      LICKPKTLKS-GKQKNVDKEFHLLATVFDENLSWYLDDNINRYAKQPKSV
tr_Q9BQS7Hephaestin_Homosapien      LVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLL
tr_Q9Z0Z4Hephaestin_Musmusculu      LVCKAGALGADGKQKGVDKEFFLLFTVFDENESWYNNANQAAGMLDSRLL
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      LICYKESVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGV
tr_Q7TN96FactorVIII_Rattusnorv      LICCKESVDQRGNQMMSDERNVILFSVFDENRSWYISENMRRFLPDEAHV
sp_P12263_FA8_PIGCoagulationfa      LICYKESVDQRGNQMMSDKRNVILFSVFDENQSWYLAENIQRFLPNPDGL
tr_O62730FactorVIII_Canisfamil      LICYKESVDQRGNQMMSDKRNVILFSVLDENRSWYLTEDMQRFLPNADVV
tr_Q804W6CoagulationfactorVIII      LICKNEAIDQRGRLVGPDKDWSLVFAVFDENNSWYMKENIHNTTQTPTGY
sp_Q06194_FA8_MOUSECoagulation      LICYKESVDQRGNQMMSDKRNVILFSIFDENQSWYITENMQRFLPNAAKT
tr_Q7TPK2Ac2_120_Rattusnorvegi      --SEALVVRHMPFLRVADMEQEVVFAMFDENKSWYIEDNINKFCENPDEV
tr_O88783Murinecoagulationfact      LICKSRSLDQRGVQRVADIEQQAVFAVFDENKSWYIEDNINKFCENPDEV
sp_Q28107_FA5_BOVINCoagulation      LICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYIEDNIYKFCENPEKV
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      LICKSRSLDKRGIQRTADIEQKAVFAVFDENKSWYIEDNIYKFCENPEKV
sp_P12259_FA5_HUMANCoagulation      LICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNINKFCENPDEV
tr_Q7SZN0PseutarinCprecursor_P      LVCKHKALSVKGVQNKADVEQHAVFAVFDENKSWYLEDNIKKYCSNPSAV
tr_Q804W5CoagulationfactorVpre      LICKSESLNVRNVQLRADKEQHAMFAVFDENMSWYLDDNIRYRCEHS-KV
tr_Q90X47SC_bZ20I5.3_Novelprot      LICKSQSLNKKNVQLKADKEQHAMFTVFDENKSWYQDENINTYCSDPKKV
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      DKEDEDFQES-----NKMH----SMNGFMYGNQSWPHMCLGESIVWYLFS
sp_P00450_CERU_HUMANCeruloplas      DKEDEDFQES-----NKMH----SMNGFMYGNQPGLTMCKGDSVVWYLFS
tr_Q7ZU12Cpprotein_Brachydanio      NKEDADFQES-----NKMH----SLNGYMYGNLKGLNMCKGDKVSWHLSG
tr_Q9BQS7Hephaestin_Homosapien      SEDIEGFQDS-----NRMH----AINGFLFSNLPRLDMCKGDTVAWHLLG
tr_Q9Z0Z4Hephaestin_Musmusculu      SEDVEGFQDS-----NRMH----AINGFLFSNLPRLDMCKGDTVAWHLLG
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      QLEDPEFQAS-----NIMH----SINGYVFDSLQ-LSVCLHEVAYWYILS
tr_Q7TN96FactorVIII_Rattusnorv      QLQDPEFEAS-----NLMH----SINGYVFDGLE-LRVCLHEVAAWHVLS
sp_P12263_FA8_PIGCoagulationfa      QPQDPEFQAS-----NIMH----SINGYVFDSLQ-LSVCLHEVAYWYILS
tr_O62730FactorVIII_Canisfamil      QPHDPEFQLS-----NIMH----SINGYVFDNLQ-LSVCLHEVAYWYILS
tr_Q804W6CoagulationfactorVIII      NDTDPDVYNS-----HVIY----TVNGIMFRRRQ-FVICKTDVAFWHVAS
sp_Q06194_FA8_MOUSECoagulation      QPQDPGFQAS-----NIMH----SINGYVFDSLE-LTVCLHEVAYWHILS
tr_Q7TPK2Ac2_120_Rattusnorvegi      KRDDPKFYES-----NIMN----TINGYVPESISTLGFCFDDAVQWHFCS
tr_O88783Murinecoagulationfact      KRDDPKFYES-----NIMS----TINGYVPESISTLGFCFDDTVQWHFCS
sp_Q28107_FA5_BOVINCoagulation      KRDDPKFYESNIMSN----FTLPAINGYVPESIPILGFCFDDTVQWHFCS
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      KRDDPKFYES-----NIMS----TINGYVPESIPTLGFCFDDTVQWHFCS
sp_P12259_FA5_HUMANCoagulation      KRDDPKFYES-----NIMS----TINGYVPESITTLGFCFDDTVQWHFCS
tr_Q7SZN0PseutarinCprecursor_P      KKDDPKFYKS-----NVMY----TLNGYASDRTEVLRFHQSEVVQWHLTS
tr_Q804W5CoagulationfactorVpre      NKADPDFYKS-----NVMH----SINGYVFESSPVLGFCNGEVATWHVSS
tr_Q90X47SC_bZ20I5.3_Novelprot      KKDDPEFYKS-----NVMH----TINGYVYESGQELGFCHGEIVTWHVSS
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      AGNEADVHGIYFSGNTYLCKGEERDTANLFPHKSLTLLMNPDTKGTFDVE
sp_P00450_CERU_HUMANCeruloplas      AGNEADVHGIYFSGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVE
tr_Q7ZU12Cpprotein_Brachydanio      LGSETDIHGLYFEGNRFLYKETRRDTINVFPHISHTVIMEPDSMGQFEVN
tr_Q9BQS7Hephaestin_Homosapien      LGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIY
tr_Q9Z0Z4Hephaestin_Musmusculu      LGTETDVHGVMFEGNTVQLQGMRKGAVMLFPHTFVTAIMQPDNPGIFEIY
tr_Q804X3CoagulationfactorVIII      ---------------------------------------------VWTLG
sp_P00451_FA8_HUMANCoagulation      IGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILG
tr_Q7TN96FactorVIII_Rattusnorv      VGAQTDFLSVFFSGHTFRHRAVYADTLTVFPHSGVTVFMSMDNPGVWVLG
sp_P12263_FA8_PIGCoagulationfa      VGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLG
tr_O62730FactorVIII_Canisfamil      VGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLG
tr_Q804W6CoagulationfactorVIII      VGTPTEFLSVYFTGNLFQHQGLYQSVLTLFPMSGLTVSMEPEVVGEWEIG
sp_Q06194_FA8_MOUSECoagulation      VGAQTDFLSIFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLG
tr_Q7TPK2Ac2_120_Rattusnorvegi      VGTHDDILTVHFTGHSFIYGRRHEDTLTLFPMSGESVTVVMDNIGTWMLT
tr_O88783Murinecoagulationfact      VGTHDDILTIHFTGHSFIYGRRHEDTLTLFPMRGESVTVTMDNVGTWMLT
sp_Q28107_FA5_BOVINCoagulation      VGTQNDILTIHFTGHSFIYGKRHEDTLTLFPMQGESVTVTMDNVGTWMLT
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      VRTHDNILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLT
sp_P12259_FA5_HUMANCoagulation      VGTQNEILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLT
tr_Q7SZN0PseutarinCprecursor_P      VGTVDEIVPVHLSGHTFLSKGKHQDILNLFPMSGESATVTMDNLGTWLLS
tr_Q804W5CoagulationfactorVpre      VGAQDYIQTATFYGHTFELNERTEDFLSLYPMTGETISMNMDNIGVWLLA
tr_Q90X47SC_bZ20I5.3_Novelprot      VGEQDYIQTATFYGHTFELKNREEDILSLFPMTGETITMNMVNIGIWLLA
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      CLTTDHYTGGMKQKYTVNQCQ-----------------------------
sp_P00450_CERU_HUMANCeruloplas      CLTTDHYTGGMKQKYTVNQCR-----------------------------
tr_Q7ZU12Cpprotein_Brachydanio      CKTTDHYHGGMRANYTVEKCR-----------------------------
tr_Q9BQS7Hephaestin_Homosapien      CQAGSHREAGMRAIYNVSQCPG----------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      CQAGSHREEGMQAIYNVSQCSS----------------------------
tr_Q804X3CoagulationfactorVIII      CMNPDFRDRGMHAKFTVTQCQLEG-SLDEEEYEDYEE----EDFELQPRG
sp_P00451_FA8_HUMANCoagulation      CHNSDFRNRGMTALLKVSSCDKNTGDYYEDSYEDISAYLLSKNNAIEPRS
tr_Q7TN96FactorVIII_Rattusnorv      CHNPDFRESGMTALLKVSSCDEGVSDYYGETYEGVLAPLAN-DNAVDPRS
sp_P12263_FA8_PIGCoagulationfa      CHNSDLRNRGMTALLKVYSCDRDIGDYYDNTYEDIPGFLLSGKNVIEPRS
tr_O62730FactorVIII_Canisfamil      CHNSDFRNRGMTALLKVSSCNRNIDDYYEDTYEDIPTPLLNENNVIKPRS
tr_Q804W6CoagulationfactorVIII      AFDGSLKSRGMSIQYTVLTCER----------------------------
sp_Q06194_FA8_MOUSECoagulation      CHNSDFRKRGMTALLKVSSCDKSTSDYYEEIYEDIPTQLVNENNVIDPRS
tr_Q7TPK2Ac2_120_Rattusnorvegi      TMSSNPRRRNLRLRFRDVKCNRN--DDDDEDSYEIYQPLEPTSMTTRKIH
tr_O88783Murinecoagulationfact      TMNSNPKRRNLRLRFRDVKCNRD--YDNE-DSYEIYEPPAPTSMTTRRIH
sp_Q28107_FA5_BOVINCoagulation      TMNSNPRSKKLRLRFRDAKCIRN--DDDD-SYEIIYEPSGSTAMTTKKIH
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      TMNSNPRNKKLQLKFRDVKCIRD--DDED-SYEIIYEPSSSTTLTTRKMH
sp_P12259_FA5_HUMANCoagulation      SMNSSPRSKKLRLKFRDVKCIPD--DDED--SYEIFEPPESTVMATRKMH
tr_Q7SZN0PseutarinCprecursor_P      SWGSCEMSNGMRLRFLDANYDDE--DEGN---------------------
tr_Q804W5CoagulationfactorVpre      SLNSHGTTKGMRVKFQDVECYRDYQYEYDDSTNVEFNVWNPLSLDTIQEN
tr_Q90X47SC_bZ20I5.3_Novelprot      SLNSHDSTKGMRVKFKDLECFRDYVIEYDYED-GKFTAWKPPTINEIKKE
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      FSKRKNKRRPCVS------------------------------------E
sp_P00451_FA8_HUMANCoagulation      FSQ-NSRHPSTRQ------------------------------------K
tr_Q7TN96FactorVIII_Rattusnorv      FSQNSNHLHSRKK--------------------------------KSNTP
sp_P12263_FA8_PIGCoagulationfa      FAQNSRPPSASQK-------------------------------------
tr_O62730FactorVIII_Canisfamil      FSQNSRHPSTKEK-------------------------------------
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      FFQNTNHPNTRKK-------------------------------------
tr_Q7TPK2Ac2_120_Rattusnorvegi      DSVENDFGIENEDDDYQYELASTLGIRSFRKSLLNPKEDEFNLTALALEN
tr_O88783Murinecoagulationfact      DSLENEFGIDNEDDDYQYLLASSLGIRSFKNSSLNPEENEFNLTALALEN
sp_Q28107_FA5_BOVINCoagulation      DSSEIED-ENDADSDYQDELALILGLRSFRNSSLNQEKDELNLTALALEK
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      DSSENKEEENDDEYDYQDLLASVLGIRSFRNSSLYQEDDEFNLTALALEN
sp_P12259_FA5_HUMANCoagulation      DRLEPEDEESDADYDYQNRLAAALGIRSFRNSSLNQEEEEFNLTALALEN
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      EKPILVENKNGEFDSYTEDLANELGLRSLK--------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      EP---VRARPDVVDEYSDLFAETLNLRTFNNVKDEVEIIDLTFLDQDDGL
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      QPNNVTSPKNGTRKPALCLTESSHRALPHNITNPGPSSNGTSAFPG-SPH
sp_P00451_FA8_HUMANCoagulation      QFNATTIPENDIEKTDPWFAHRTPMPKIQNVS----SSDLLMLLRQ-SPT
tr_Q7TN96FactorVIII_Rattusnorv      MRFPLSHPTQHGSFWSDSQGDVHDAVHRAHSPAAAHSNEGPAEAAQLEPK
sp_P12263_FA8_PIGCoagulationfa      QFQTITSPEDDVE-LDPQSGERTQALEELSVP----SGDGSMLLGQ-NPA
tr_O62730FactorVIII_Canisfamil      QLKATTTPENDIEKIDLQSGERTQLIKAQSVS----SSDLLMLLGQ-NPT
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      KFKDSTIPKNDMEKIEPQFEEIAEMLKVQSVS----VSDMLMLLGQSHPT
tr_Q7TPK2Ac2_120_Rattusnorvegi      SSEFISLSTDGVVDSKSSR--NLSKITNNNLNDSQRTLSGSGATIAGILL
tr_O88783Murinecoagulationfact      SSEFISPSTDRVVDSNSSR--ILSKIINNNLKDFQRTLPGSGATVAGTLL
sp_Q28107_FA5_BOVINCoagulation      DSEFIPPSANRSLDSNSSSRSHVSRLIAKNFAESLKTLLHLEAPAAGSPL
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      NSEFIPPSTDRAVDSNSSSPGNISRAPANTFTEPRKILPHPEATKAGSPR
sp_P12259_FA5_HUMANCoagulation      GTEFVSSNTDIIVGSNYSSPSNISKFTVNNLAEPQKAPSHQQATTAGSPL
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      --------------------------------------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      LPIVEEKSLGSSNENLHNATLQSFIETHGLLMEEGDLDKGESSNKVLNDS
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      PDDVSTSSLPETYYDPVSYES---------------------------FL
sp_P00451_FA8_HUMANCoagulation      PHGLSLSDLQEAKYETFSDDPSPGAIDSNNSLSEMTHFRPQLHHSGDMVF
tr_Q7TN96FactorVIII_Rattusnorv      PHPGEKMALPPSWLRAKR--------------------------------
sp_P12263_FA8_PIGCoagulationfa      PHGSSSSDLQEARNEADDYLPG--ARERNTAPSAAARLRPELHHSAERVL
tr_O62730FactorVIII_Canisfamil      PRGLFLSDLREATDRADDHSRG--AIERNKGPPEVASLRPELRHSEDREF
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      PHGLFLSDGQEAIYEAIHDDHSPNAIDSNEGPSKVTQLRPESHHSEKIVF
tr_Q7TPK2Ac2_120_Rattusnorvegi      GNLTGLGKNSVLNPSTEYHSSSYYENDMED-PQSNITVVYLLPLGAKGSG
tr_O88783Murinecoagulationfact      RNLIGLDENFVLNSSTEHRSSSYHENDMEN-PQSNITMVYLLPLGPKGSG
sp_Q28107_FA5_BOVINCoagulation      EHAG-LDKNSALNPPMAEHSSPYSEDPREDHPLSDVTGVSLLPFGT-GFK
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      RHTG-LVKNLVLNRRRTQHSDPYSEDPIENPLQSVITGISLLPFGTEGFR
sp_P12259_FA5_HUMANCoagulation      RHLI--GKNSVLNSSTAEHSSPYSEDPIEDPLQPDVTGIRLLSLGAGEFK
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      ------------------QQSNGSDVEQLDLSFLDYEVVDVSN-------
tr_Q90X47SC_bZ20I5.3_Novelprot      TDKALLETTTTFDSNRVVALNNETDSIILDFPIVERKVRSAPSKPMNEPE
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      ADEEELSKTISQDQGAGALPSRKHISGEVRGTV-----------TSRE--
sp_P00451_FA8_HUMANCoagulation      TPESGLQLRLNEKLGTTAATELKKLDFKVSSTS-----------NNLIST
tr_Q7TN96FactorVIII_Rattusnorv      ------SLVTTMEAKRKKLDLQVQVSGLPDDRTTAVVAP-----------
sp_P12263_FA8_PIGCoagulationfa      TPEP--------------EKELKKLDSKMSSSSDLLKTS-----------
tr_O62730FactorVIII_Canisfamil      TPEPELQLRLNENLGTNTTVELKKLDLKISSSSDSLMTS-----------
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      TPQPGLQLRSNKSLETTIEVKWKKLGLQVSSLPSNLMTTTILSDN-----
tr_Q7TPK2Ac2_120_Rattusnorvegi      SREQTKPKTIKTGRPHRMKHRFSWMKAPAGKTG-RHSNPKNTSSRMKSEE
tr_O88783Murinecoagulationfact      NREQDKPKTIKTGRPHMMKHRFSWMKAPAGKTG-RHSNPKNSYSGMKSEE
sp_Q28107_FA5_BOVINCoagulation      NRKPAKHQRFQVGRGQAAKHKFSQTRFPAHKTRTRLSQDNSSSSRMGPWE
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      NREHPKHKRFKAGRDQAAKHRFSQMEFPAHKTGRHISQDNSSSSSMGPLE
sp_P12259_FA5_HUMANCoagulation      SQEHAKHKGPKVERDQAAKHRFSWMKLLAHKVGRHLSQDTGSPSGMRPWE
tr_Q7SZN0PseutarinCprecursor_P      -------------------------EEEEEDDGDIFADIFIPSEVVKKKE
tr_Q804W5CoagulationfactorVpre      -----------------------------------ETQINFTKTKNDNFA
tr_Q90X47SC_bZ20I5.3_Novelprot      SVTMNFKTTEHINSSLERINAIYSPITETNINTMTETHTDFSITPFDGST
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      ----------GLYQSKPAPEDAMVERKVTNVLEVQEPAKAAVVQAGGTLQ
sp_P00451_FA8_HUMANCoagulation      IPSDN--LAAGTDNTSSLGPPSMPVHYDSQLDTTLFGKKSSPLTESGGPL
tr_Q7TN96FactorVIII_Rattusnorv      ------------DDPMAACKKAGSSGFPDESSPAALGKKMYPRIRPHGPL
sp_P12263_FA8_PIGCoagulationfa      PTIPSDTLSAETERTHSLGPPHPQVNFRSQLGAIVLGKNSSHFIGAGVPL
tr_O62730FactorVIII_Canisfamil      PTIPSDKLAAATEKTGSLGPPNMSVHFNGHLGTIVFGNNSSHLIQSGVPL
tr_Q804W6CoagulationfactorVIII      -------------EDLLVDHELDEVDFSDYVDNMVLG-------------
sp_Q06194_FA8_MOUSECoagulation      -------LKATFEKTDSSGFPDMPVHSSSKLSTTAFGKKAYSLVGSHVPL
tr_Q7TPK2Ac2_120_Rattusnorvegi      DIP-----------------SDLLLLKQKVASKLLNRQWHMASEKGSYEI
tr_O88783Murinecoagulationfact      DIP-----------------SELIPLKQKITSKFLNRRWRVASEKGSYEI
sp_Q28107_FA5_BOVINCoagulation      DIP-----------------SDLLLLQQKDPYKILNGEWHLVSEKGSYEI
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      DLS-----------------SDLLLLERKDPSTIN-GKWHLVSEKGSYEI
sp_P12259_FA5_HUMANCoagulation      DLPSQDTGSPSRMRPWKDPPSDLLLLKQSNSSKILVGRWHLASEKGSYEI
tr_Q7SZN0PseutarinCprecursor_P      EVP-----------------------------------------------
tr_Q804W5CoagulationfactorVpre      AEING---------------LNDTSISNRLDVQNLTGADLLNQQINWNST
tr_Q90X47SC_bZ20I5.3_Novelprot      GEMNFTL-------------EDDTALLNSSESEPLQSNQNSENRIAFQEE
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      MLETETQKPMAHTYDLWNSTVFAAGKGPLQGTRSSFQQDGPEHSLGLQVT
sp_P00451_FA8_HUMANCoagulation      SLSEENNDSKLLESGLMNSQESSWGKNVSSTESGRLFKGKRAHGPALLTK
tr_Q7TN96FactorVIII_Rattusnorv      SIIEGNRDSNSSDSTLMYRLGSPPGDATSWTENRRGLGEKRSHRVAFLAR
sp_P12263_FA8_PIGCoagulationfa      GSTEEDHES-------------SLGENVSPVESDGIFEKERAHGPASLTK
tr_O62730FactorVIII_Canisfamil      ELSEEDNDSKLLEAPLMNIQESSLRENVLSMESNRLFKEERIRGPASLIK
tr_Q804W6CoagulationfactorVIII      ------------------------------------LRGMRPRNHTVLLK
sp_Q06194_FA8_MOUSECoagulation      NASEENSDSNILDSTLMYSQESLPRDNILSIENDRLLREKRFHGIALLTK
tr_Q7TPK2Ac2_120_Rattusnorvegi      IPANGENTDIDKLTNSPQNQNISTPWGASTSRINTTGKPSNLPTFSRFRH
tr_O88783Murinecoagulationfact      IAANGEDTDVDKLTNSPQNQNITVPRGESTSHTNTTRKPSDLPTFSGVGH
sp_Q28107_FA5_BOVINCoagulation      IQDANENKTVNKLPNSPQND--SRTWGENIPFKNSHGKQSGHPTFLVTRR
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      VQDADEDMAVNKLPNNPQNA--SRSWGENIPFTNKHGKQRGHPIFVTR-H
sp_P12259_FA5_HUMANCoagulation      IQDTDEDTAVNNWLISPQNA--SRAWGESTPLANKPGKQSGHPKFPRVRH
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      VMQNNSTLAFLNHSVN------------------EIQKLWNHSPQTKNTF
tr_Q90X47SC_bZ20I5.3_Novelprot      LNAKDGTDVDSNNSVKNQIFKYNVPSGDTLSNSSKIQVEEDFVLLDSSYF
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      SSEGADVTPLNLHESREPSNTGP---------------------------
sp_P00451_FA8_HUMANCoagulation      DNALFKVSISLLKTNKTSNNSATNRKTHIDGPSLLIENSPSVWQNI-LES
tr_Q7TN96FactorVIII_Rattusnorv      GNTLLSDVDEKSHAPGPTSVGNSTAAVQDTILEICSEILEVTPP------
sp_P12263_FA8_PIGCoagulationfa      DDVLFKVNISLVKTNKARVYLKTNRKIHIDDAALLTEN------------
tr_O62730FactorVIII_Canisfamil      DNALFKVNISSVKTNRAPVNLTTNRKTRVAIPTLLIENSTSVWQDIMLER
tr_Q804W6CoagulationfactorVIII      VCNKVPINNSTHSVNTSTLN------------------------------
sp_Q06194_FA8_MOUSECoagulation      DNTLFKDNVSLMKTNKTYNHSTTNEKLHTESPTSIENSTTDLQDAI-LKV
tr_Q7TPK2Ac2_120_Rattusnorvegi      KSPHVRQEEESGDFKKRQLFIRTRKKKKNRK-------------------
tr_O88783Murinecoagulationfact      KSPHVRQEEENSGFQKRQLFIRTRKKKKNKKLALHSPLSPRGFDPLRGHN
sp_Q28107_FA5_BOVINCoagulation      KPLQDRQDRRNSRLKEGLPLIRTRRKKKEEKPAYHVPLSPRSFHPLRGEV
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      KLLQERQDEGNSILKKGRFFIRTRRKKKERKPVHHVPLSPRSFNPLRGEA
sp_P12259_FA5_HUMANCoagulation      KSLQVRQDGGKSRLKKSQFLIKTR-KKKKEKHTHHAPLSPRTFHPLRSEA
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      SVIDTDLEAAATVNNTS-ALSVDTNYSKEITN------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      SEMSTTMEYDVSQKDTVKGESKETAQSQELSS------------------
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      ----------------------TLGSNHNSSFTTDSPLGPSARTEDIGTS
sp_P00451_FA8_HUMANCoagulation      DTEFKKVTPLIHDRMLMDKNATALRLNHMSNKTTSSKNMEMVQQKKEGPI
tr_Q7TN96FactorVIII_Rattusnorv      ----------IHDRILSDKSATYLRPHRTPDRITSTERKDIRHEKDGDLV
sp_P12263_FA8_PIGCoagulationfa      ----------RASATFMDKNTTASGLNHVSNWIKG---------------
tr_O62730FactorVIII_Canisfamil      NTEFKEVTSLIHNETFMDRNTTALGLNHVSNKTTLSKNVEMAHQKKEDPV
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      NSEIQEVTALIHDGTLLGKNSTYLRLNHMLNRTTSTKNKDIFHRKDEDPI
tr_Q7TPK2Ac2_120_Rattusnorvegi      -------RLLNHSLLLHKSNETALSTDLNQTSP--PVSTDRSLPDYNQN-
tr_O88783Murinecoagulationfact      HSPFPDRRLLNHSLLLHKSNETALSPDLNQTSP--SMSTDRSLPDYNQY-
sp_Q28107_FA5_BOVINCoagulation      NASFSD-RRHNHSLLLHASNETSLSIDLNQTFPSMNLSLAASLPDHDQTS
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      NTPFSD-RRQNHSLLLHESNETFPPTDLNQTFPSMNLSLIASHPDHNQN-
sp_P12259_FA5_HUMANCoagulation      YNTFSE-RRLKHSLVLHKSNETSLPTDLNQTLPSMDFGWIASLPDHNQN-
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      -----LAGTLQGKNLTASDSNVTSVSRIN---------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      -----TKKTYSGEIILESLPDITSAFNLNSSSVLRNNSLESNESSNETLF
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      QSHSVESNRSSSELDAKLNKRP-HKVVSQGFNGSLGGENISFSDLQRVQE
sp_P00451_FA8_HUMANCoagulation      PPDAQNPDMSFFKMLFLPESAR-WIQRTHGKNSLNSGQGPSPKQLVSLGP
tr_Q7TN96FactorVIII_Rattusnorv      PQDADDTSAPFSEAPFLSESTD-WLKEANGDNSAKPEQEPSPEQLVYLMY
sp_P12263_FA8_PIGCoagulationfa      ---------------------------PLGKNPLSSERGPSPELLTSSGS
tr_O62730FactorVIII_Canisfamil      PLRAENPDLSSSKIPFLPD-----WIKTHGKNSLSSEQRPSPKQLTSLGS
tr_Q804W6CoagulationfactorVIII      ---------------------------------ATDGRRCYLKKVTLTPP
sp_Q06194_FA8_MOUSECoagulation      PQDEENTIMPFSKMLFLSESSN-WFKKTNGNNSLNSEQEHSPKQLVYLMF
tr_Q7TPK2Ac2_120_Rattusnorvegi      ----------------------PSNDTEQMSSSLDLFQSVPPEEHSPTFP
tr_O88783Murinecoagulationfact      ----------------------SKNDTEQMSSSLDLYQSVPAEEHSPTFP
sp_Q28107_FA5_BOVINCoagulation      ----------------------PNDTTSQTSSPPDLYPTVSPEEHYQIFP
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      ----------------------LPNDTHQTSSPLDLYQTVTPDEPYQTAP
sp_P12259_FA5_HUMANCoagulation      ----------------------SSNDTGQASCPPGLYQTVPPEEHYQTFP
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      ----------------------------MPATRIPSCLSVSKAHVGKNNS
tr_Q90X47SC_bZ20I5.3_Novelprot      ----------------------MSSNATFSDSTNATSSDSSTATFADFSN
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      QIL-TDMRNSLPANSSMEEAKGTFAHSNDLEPSRYLPTE-----------
sp_P00451_FA8_HUMANCoagulation      EKS-VEGQNFLSEKNKVVVGKGEFTKDVGLKEMVFPSSRNLFLTNLDNLH
tr_Q7TN96FactorVIII_Rattusnorv      IKC-MENQSFSSEKNKMIAGQGGFTKNTGLEDTVFPRKTSVFLTTVAKRQ
sp_P12263_FA8_PIGCoagulationfa      GKS-VKGQ-SSGQG-RIRVAVEEEELSKGKE-MMLPNSELTFLTNSADVQ
tr_O62730FactorVIII_Canisfamil      EKS-VKDQNFLSEE-KVVVGEDEFTKDTELQ-EIFPNNKSIFFANLANVQ
tr_Q804W6CoagulationfactorVIII      GG------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      KKY-VKNQSFLSEKNKVTVEQDGFTKNIGLKDMAFPHNMSIFLTTLSNVH
tr_Q7TPK2Ac2_120_Rattusnorvegi      TQD----------------------------------------------P
tr_O88783Murinecoagulationfact      AQD----------------------------------------------P
sp_Q28107_FA5_BOVINCoagulation      IQDS--------------------------------DPTHSTTAPSNRSP
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      IQD----------------------------------------------L
sp_P12259_FA5_HUMANCoagulation      IQD----------------------------------------------P
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      SDG-----------------------------------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      TTF-----------------------------------------------
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      ERDELILEAVFQDATATKDLPETDSLVLPQSNLVANDTRQFPNALSMGVP
sp_P00451_FA8_HUMANCoagulation      ENNTHNQEKKIQEEIEKKETLIQENVVLPQIHTVTGTKNFMKNLFLLSTR
tr_Q7TN96FactorVIII_Rattusnorv      ESGRHNQE-NIPQAVTEKEAPIEEKGALPQVHIATGSKNFPRDMFVLGTG
sp_P12263_FA8_PIGCoagulationfa      GNDTHSQGKKSREEMERREKLVQEKVDLPQVYTATGTKNFLRNIFHQSTE
tr_O62730FactorVIII_Canisfamil      ENDTYNQEKKSLEEIERKEKLTQENVALPQAHTMIGTKNFLKNLFLLSTK
tr_Q804W6CoagulationfactorVIII      EDANITSGERIPEDILEELQLDGEVTAAPSGILRVGEQALRR--------
sp_Q06194_FA8_MOUSECoagulation      ENGRHNQEKNIQEEIEK-EALIEEKVVLPQVHEATGSKNFLKDILILGTR
tr_Q7TPK2Ac2_120_Rattusnorvegi      NQTHSTTDPSYRSSPPEPSQGIDYDLSHEFYSDDISQTS-FFPDQSQKSP
tr_O88783Murinecoagulationfact      DQTHSTTDPSYRSSPPELSQGLDYDLSHDFYPDDIGLTS-FFPDQSQKSS
sp_Q28107_FA5_BOVINCoagulation      DPTHSTTAPSNRSPPTQPSQIPNYDLRNRAIPTDVSQIFPSLELEVWQTA
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      DPTHSTAVPSHQSSLPEPIQMHDYDLRNKASPTDVSEMFFSLKLKAGHRT
sp_P12259_FA5_HUMANCoagulation      DQMHSTSDPSHRSSSPELSEMLEYDRSHKSFPTDISQMSPSSEHEVWQTV
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      ------TNSSTLEAHGPYLNSSGKVNPFISKSGNVAAVLLKNGSVTVKLP
tr_Q90X47SC_bZ20I5.3_Novelprot      ------SNATFSDFSNRISQMSDSSNATLSDSSNATLSDSSNATLSDSSN
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      GSRPRQARSLQSRGLEHGLGLPSPTSGSRESLIVGNGAGQDRRSS-----
sp_P00451_FA8_HUMANCoagulation      QNVEGSYDGAYAPVLQDFRSLNDSTNRTKKHTAHFSKKGEEENLEGLGNQ
tr_Q7TN96FactorVIII_Rattusnorv      QN-INLHEETYVPVHKNVPWTRNPTDTRQIPMVHFFKKRKEEETNSGGLV
sp_P12263_FA8_PIGCoagulationfa      PSVEGFDGGSHAPVPQDSRSLNDSAERAETHIAHFSAIREEAPLEAPGNR
tr_O62730FactorVIII_Canisfamil      QNVAGLEEQPYTPILQDTRSLNDSPHSEGIHMANFSKIREEANLEGLGNQ
tr_Q804W6CoagulationfactorVIII      -------------------RRQAEDNSTDFDIYSGDEGGEE---------
sp_Q06194_FA8_MOUSECoagulation      QN--ISLYEVHVPVLQNITSINNSTNTVQIHMEHFFKRRKDKETNSEGLV
tr_Q7TPK2Ac2_120_Rattusnorvegi      LTSDDGQAIPSSDLNLFTISPELDQTIIYPDLDQLFLSPDDIQKTSSQDL
tr_O88783Murinecoagulationfact      FSSDDDQAIPSSDLSLFTISPELDQTIIYPDLDQLLLSPEDNQKTSSPDL
sp_Q28107_FA5_BOVINCoagulation      TSLDLSQPSISPDLGQMALSPDPGQESLSPDLGQTSLSPDLSQESLSPDL
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      TSPDLNQTSLSPELSQTTLSPDPGHVTLSPDLSQTTLSPDLSHTTLSPDL
sp_P12259_FA5_HUMANCoagulation      ISPDLSQVTLSPELSQTNLSPDLSHTTLSPELIQRNLSPALGQMPISPDL
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      MSKEELDNTSLKNPSNKTSASSSTPSVSTN--------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      ATLSDSSNATLSNSSNATFSDSSNKTFSDSSNATLFGVSYSSNTTLSDFS
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      -----------------------------------SLLTQAAPQSQAVMA
sp_P00451_FA8_HUMANCoagulation      TKQIVEKYACTTRISPNTSQQNFVTQRSKRALKQFRLPLEETELEKRIIV
tr_Q7TN96FactorVIII_Rattusnorv      N-----------------------KTRETVRNYPSQKNSVARRREQASGR
sp_P12263_FA8_PIGCoagulationfa      T--------------GPGPR-SAVPRRVKQSLKQIRLPLEEIKPERGVVL
tr_O62730FactorVIII_Canisfamil      TNQMVERFPSTTRMSSNASQ-HVITQRGKRSLKQPRLSQGEIKFERKVIA
tr_Q804W6CoagulationfactorVIII      -----------------------------------RSEIQERPAENRTTA
sp_Q06194_FA8_MOUSECoagulation      N-----------------------KTREMVKNYPSQKNITTQRSKRALGQ
tr_Q7TPK2Ac2_120_Rattusnorvegi      G-----------------QVTLSPDENQETSSQDLGQVTLSPNENQETSS
tr_O88783Murinecoagulationfact      G-----------------QVPLSPDDNQKTSSPDLGQVSLSPDDNQKTSS
sp_Q28107_FA5_BOVINCoagulation      G-----------------QTALSPDPSQESLSPDLGQTALSPDPSQESLS
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      G-----------------HTTLSPDLSHTTLSPDLSQTTLSPDLSHTTLS
sp_P12259_FA5_HUMANCoagulation      S-----------------HTTLSPDLSHTTLSLDLSQTNLSPELSQTNLS
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      --------------------------------------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      L-----------------ESEMTEYILSSANDTIKSHSEVVSNTSQLSSS
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      ASSSALQDGNNGTDVASNWDPVSPGAAGRAVGLQSPALAAMQPGGGAAWG
sp_P00451_FA8_HUMANCoagulation      DDTSTQWSKNMKHLTPSTLTQIDYNEKEKGAITQSPLSDCLTRSHSIPQA
tr_Q7TN96FactorVIII_Rattusnorv      IKASARWLPDVNRSIQSLLKQIDHRKERKKFIIESRSADSSGTKSPTQTN
sp_P12263_FA8_PIGCoagulationfa      NATSTRWSE-----------------------------------------
tr_O62730FactorVIII_Canisfamil      NDTSTQWSKNMNYLAQGTLTQIEYNEKEKRAITQSPLSDCSMRNHVTIQM
tr_Q804W6CoagulationfactorVIII      NATG----------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      FRLSTQWLKTINCSTQCIIKQIDHSKEMKKFITKSSLSDSSVIKSTTQTN
tr_Q7TPK2Ac2_120_Rattusnorvegi      QDLGQVTLSPDDIQETSSQDLGQVTLSPDENQETSSPDLGQVPLTPDD--
tr_O88783Murinecoagulationfact      PDLGQVPLSLDDNQKTTSPDLGQVPLSPDDNQMITSPDLGQVPLSSDN--
sp_Q28107_FA5_BOVINCoagulation      PDLGQTALSPDPGQESLSPDLGQTSLSPDLSQESLSPDLGQTALSPDP--
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      PDLGHTTLSPDLSHTTLSPDLGHATLSPDLSHTTLSPDLGHTTLSPDLGH
sp_P12259_FA5_HUMANCoagulation      PALGQMPLSPDLSHTTLSLDFSQTNLSPELSHMTLSPELSQTNLSPALGQ
tr_Q7SZN0PseutarinCprecursor_P      -----------------------VNFVPDPESDALAKELG----------
tr_Q804W5CoagulationfactorVpre      -----------DIMTSSSKELSSSESSKEVFIYVKDKKAGLIKTTSVK--
tr_Q90X47SC_bZ20I5.3_Novelprot      ESTENISLLYGSLNASSMKNDSESESEEEVVIYLNKNHSEAILTSHLD--
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      --------------------------------------------------
sp_P00451_FA8_HUMANCoagulation      NRSPLPIAKVSSFPSIRPIYLTRVLFQDNSSHLPA----ASYRKKDSGVQ
tr_Q7TN96FactorVIII_Rattusnorv      HSPSHVVKMSAFPPRDIRRIESRDSSQVWVSSYAY-----DFETGSSRIR
sp_P12263_FA8_PIGCoagulationfa      --------------------------------------------------
tr_O62730FactorVIII_Canisfamil      NDSALPVAKESASPSVRHTDLTKIPSQHNSSHLPASACNYTFRERTSGVQ
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      SSDSHIVKTSAFPPIDLKRSPFQNKFSHVQASSYI----YDFKTKSSRIQ
tr_Q7TPK2Ac2_120_Rattusnorvegi      -------NQK-TSPDLGQVLLSLDDKQKTYFLDPGQVPISSDQSWETSST
tr_O88783Murinecoagulationfact      --------QKTSSPDLGQVPLFPEDNQ-NYFLDLSQVPLSSDQNQETSST
sp_Q28107_FA5_BOVINCoagulation      -------SQESLSPDLGQTALSPDPSQESLSPDLGQTSLSPDLGQESLSP
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      TTLSPDFSQTTLSPDLGHTTLSSDVSHTTLSPDLSHTTLSPDLSHTTLSP
sp_P12259_FA5_HUMANCoagulation      MPISPDLSHTTLSLDFSQTNLSPELSQTNLSPALGQMPLSPDPSHTTLSL
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      ---------------------------------TSGHNWTYDGTHKIVSA
tr_Q90X47SC_bZ20I5.3_Novelprot      ---------------------------------QKEEHWGYESKHELVHK
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      ---------------------ALWGKQAQGRSQLEEETNAVEQPDRERTW
sp_P00451_FA8_HUMANCoagulation      ESSHFLQGAKKNNLSLAILTLEMTGDQREVGSLGTSATNSVTYKKVENTV
tr_Q7TN96FactorVIII_Rattusnorv      ESSPFLNETETDNPSLAVPPRERFVRRGRFASPEKVNTHSAPCDKPENVV
sp_P12263_FA8_PIGCoagulationfa      -SSPILQGAKRNNLSLPFLTLEMAGGQGKISALGKSAAGPLASGKLEKAV
tr_O62730FactorVIII_Canisfamil      EGSHFLQEAKRNNLSLAFVTLGITEGQGKFSSLGKSATNQPMYKKLENTV
tr_Q804W6CoagulationfactorVIII      ------------------------INRTKELEEGNEILLTGNPGNSKRSF
sp_Q06194_FA8_MOUSECoagulation      ESNNFLKETKINNPSLAILPWNMFIDQGKFTSPGKSNTNSVTYKKRENII
tr_Q7TPK2Ac2_120_Rattusnorvegi      DLSLLTLSPKFGQTVISPDLDKMPLSSDNSQVTLSPDLSLLTLSPDFNEI
tr_O88783Murinecoagulationfact      DL--LTLSPDFGQTVLSPDLDQLPLPSDNSQVTVSPDLSLLTLSPDFNEI
sp_Q28107_FA5_BOVINCoagulation      DLGQTALSPDPSQESLSPDLGQTSLSPDLGQESLSPDLGQTALSPDLSQE
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      DLGHTTLSPDLSQTTLSPDLGHMTLSPDLSHTTLSPDLGHTTLSPDLSHT
sp_P12259_FA5_HUMANCoagulation      DLSQTNLSPELSQTNLSPDLSEMPLFADLSQIPLTPDLDQMTLSPDLGET
tr_Q7SZN0PseutarinCprecursor_P      ------------------------LIDDEGNPIIQPRREQTEDD------
tr_Q804W5CoagulationfactorVpre      EIPDDMKKYFEMSPQTN------KKKTRKVNRPHRPQKGHGMKTKRRKEY
tr_Q90X47SC_bZ20I5.3_Novelprot      ELPDHMNKYVKDKSAANSNKPKIEKEKKKVYQRVKPKKGYGMKTKKSKDY
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      FSPQHLEANATENSVPESTSGQKPDEIPTKVAPKENTSLPLSS-------
sp_P00451_FA8_HUMANCoagulation      LPKPDLPKTSGKVELLPKVHIYQKDLFPTETSNGSPGHLDLVEGSLLQGT
tr_Q7TN96FactorVIII_Rattusnorv      SSEPVSPGEAVTVALPPHVSTQEEEPLPAGSSCERRGHVDLFLEISLQRT
sp_P12263_FA8_PIGCoagulationfa      LSSAGLSEASGKAEFLPKVRVHREDLLPQKTSNVSCAHGDLGQEIFLQKT
tr_O62730FactorVIII_Canisfamil      LLQPGLSETSDKVELLSQVHVDQEDSFPTKTSNDSPGHLDLMGKIFLQKT
tr_Q804W6CoagulationfactorVIII      TVEPVTSEEMVQNYIMSEEEKLKPHHQQPGNIAVN---------------
sp_Q06194_FA8_MOUSECoagulation      FLKPTLPEESGKIELLPQVSIQEEEILPTETSHGSPGHLNLMKEVFLQKI
tr_Q7TPK2Ac2_120_Rattusnorvegi      ILSPDIDQVTLSPDLIQTSP------------------------------
tr_O88783Murinecoagulationfact      ILAPDLGQVTLSPDLIQTNP------------------------------
sp_Q28107_FA5_BOVINCoagulation      SLSPDLGQTPLSPDLSLESLSPDL--------------------------
tr_Q804X4CoagulationfactorVpre      --------------------------------------------------
sp_Q9GLP1_FA5_PIGCoagulationfa      TLSPDLGHMTLSPDLGQTTLSLDFGQTTLSPDLSHMTLSSELSHETLSPD
sp_P12259_FA5_HUMANCoagulation      DLSPNFGQMSLSPDLSQVTLSPDIS-------------------------
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      KPQPRSGLPLSPRGFNPLMS------------------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      KPQPRS--SFSPRGFG----------------------------------
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      ----------------------------------------------PAFN
sp_P00451_FA8_HUMANCoagulation      EGAIKWNEANRPGKVPFLRVATESSAKTPSKLLDPLAWDNHYGTQIPKEE
tr_Q7TN96FactorVIII_Rattusnorv      RGPVERSRGRRSGGDTEGHTENPGKTPSPLPQMPKDQRGSEAGYPKICRW
sp_P12263_FA8_PIGCoagulationfa      RGPVNLNKVNRPG-------------RTPSKLLGPPMPK----------E
tr_O62730FactorVIII_Canisfamil      QGPVKMNKTNSPGKVPFLKWATESSEKIPSKLLGVLAWDNHYDTQIPSEE
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      QGPTKWNKAKRHG--ESIKGKTESSKNTRSKLLNHHAWDYHYAAQIPKDM
tr_Q7TPK2Ac2_120_Rattusnorvegi      ---------------------------------ALNHRHKTSSADPGQAS
tr_O88783Murinecoagulationfact      ---------------------------------ALNHGHKASSADPDQAS
sp_Q28107_FA5_BOVINCoagulation      --------------------------------SQLDLKQTSPPLDLNQTS
tr_Q804X4CoagulationfactorVpre      ----------------------------------------CFQVGPTMNH
sp_Q9GLP1_FA5_PIGCoagulationfa      LSQVTLSPDLSEIPFSPDLWQTTLSSDLNETTLSPDLRQTSPHPDPDKTS
sp_P12259_FA5_HUMANCoagulation      -----------------------------DTTLLPDLSQISPPPDLDQIF
tr_Q7SZN0PseutarinCprecursor_P      --------------------------------------------------
tr_Q804W5CoagulationfactorVpre      --------------------------------------------------
tr_Q90X47SC_bZ20I5.3_Novelprot      --------------------------------------------------
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      HSTVEKPDKHVQASSDGQQ-VVLGRKDVPAETGKVEEPEEDGESGSTVGK
sp_P00451_FA8_HUMANCoagulation      WKSQEKSPEKTAFKKKDTI-LSLNACESNHAIAAINEGQNKPEIEVTWAK
tr_Q7TN96FactorVIII_Rattusnorv      RDGTVLPPRPHNLSLGAKKKPNLPRREATRVEQGEAPSLVSPE-PLVLRR
sp_P12263_FA8_PIGCoagulationfa      WESLEKSPKSTALRTKDIISLPLDRHESNHSIAAKNEGQAETQREAAWTK
tr_O62730FactorVIII_Canisfamil      WKSQKKSQTNTAFKRKDTI-LPLGPCENNDSTAAINEGQDKPQREAMWAK
tr_Q804W6CoagulationfactorVIII      --------------------------------------------------
sp_Q06194_FA8_MOUSECoagulation      WKSKEKSPEIISIKQEDTI-LSLRPHGNSHSIGANEK-QNWPQRETTWVK
tr_Q7TPK2Ac2_120_Rattusnorvegi      YPPDSGQSSPLPELNQTLPHPDLIHMQPPLLSPTPNDTSLSKTFNPLVVV
tr_O88783Murinecoagulationfact      YPPDSGQASSLPELNRTLPHPDLTHIPPPSPSPTLNNTSLSRKFNPLVVV
sp_Q28107_FA5_BOVINCoagulation      HTSESSQSLPLPEFGQTFPNADIGQMPSPPPDSTLNNTFIPEEFNPLVVV
tr_Q804X4CoagulationfactorVpre      CCVAIPQS-------------------HPVSPATENCQGYTQQLKPSIVI
sp_Q9GLP1_FA5_PIGCoagulationfa      YISESSQSVTLPEFGQTSPFPDLGQRPSPPSHSTLNNTFIPREFNPMVVV
sp_P12259_FA5_HUMANCoagulation      YPSESSQSLLLQEFNESFPYPDLGQMPSPSS-PTLNDTFLSKEFNPLVIV
tr_Q7SZN0PseutarinCprecursor_P      ----------------------------------------EEQLMKASML
tr_Q804W5CoagulationfactorVpre      ------------------------PRGARPQGLQPVNNDETLINMPVVIG
tr_Q90X47SC_bZ20I5.3_Novelprot      ------------------------PSVLTPRGSRPVSSEDELTEKPIVIG
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      ----------------------------------RQFEDFTVYLGERTYY
sp_P00450_CERU_HUMANCeruloplas      ----------------------------------RQSEDSTFYLGERTYY
tr_Q7ZU12Cpprotein_Brachydanio      ----------------------------------FWNRQSETMLHQKKYY
tr_Q9BQS7Hephaestin_Homosapien      ----------------------------------HQATPRQRYQAARIYY
tr_Q9Z0Z4Hephaestin_Musmusculu      ----------------------------------HQDSPRQHYQASRVYY
tr_Q804X3CoagulationfactorVIII      RSHAAEHGDNLN----------NETLSGLSMSESNITDYDDYSDTEQDFD
sp_P00451_FA8_HUMANCoagulation      QGRTERLCSQNPPVLKRHQREITRTTLQSDQEEIDYDDTISVEMKKEDFD
tr_Q7TN96FactorVIII_Rattusnorv      RPREASTLLPGGEMREDDGDGVTAEYDDDDDVMAEYDDDAVTVDTPEDFD
sp_P12263_FA8_PIGCoagulationfa      QGGPGRLCAPKPPVLRRHQRDISLPTFQPEEDKMDYDDIFSTETKGEDFD
tr_O62730FactorVIII_Canisfamil      QGEPGRLCSQNPPVSKHHQREITVTTLQPEEDKFEYDDTFSIEMKREDFD
tr_Q804W6CoagulationfactorVIII      ------------------------------ELSVEYDDYNQEENSTS---
sp_Q06194_FA8_MOUSECoagulation      QGQTQRTCSQIPPVLKRHQR---ELSAFQSEQEATDYDDAITIETIEDFD
tr_Q7TPK2Ac2_120_Rattusnorvegi      GLSRVDGDDVEMIPSEELESIDEDYPEDDYVTYNDPYKTDTRANVNSSRN
tr_O88783Murinecoagulationfact      GLSRVDGDDVEIVPSEEPERIDEDYAEDDFVTYNDPYRTDTRTDVNSSRN
sp_Q28107_FA5_BOVINCoagulation      GLSRDDGDYIEIIPRQKEESSEEDYGEFEFVAYNDPYQTDLRTDINSSRN
tr_Q804X4CoagulationfactorVpre      GLPHENGNYEYTSGEYYTEDTSGDEYEYYYVSFDDPYMTDPKLNVNEQRN
sp_Q9GLP1_FA5_PIGCoagulationfa      GLSRDDGDYVEIIPRQQEENSEEDYVKIDYVEYDDPYQTDVRTDINSSRN
sp_P12259_FA5_HUMANCoagulation      GLSKDGTDYIEIIPKEEVQSSEDDYAEIDYVPYDDPYKTDVRTNINSSRD
tr_Q7SZN0PseutarinCprecursor_P      GLRSFKG-----------SVAEEELKHTALALEEDAHASDPRIDSNSARN
tr_Q804W5CoagulationfactorVpre      VPRPDFSDYELYLPGDEPDHLDVDQRNVKANEYEYVNYKDPYRSNEDAKN
tr_Q90X47SC_bZ20I5.3_Novelprot      VPRRDFNDYELYIPKQD-QEADFDGLLDHPEEYEYVEYKDPYSKTADVQA
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      VDAVEVEWDYSPSRAWEKELHHLQEQ-NVSNVFLDKEEFFIG--------
sp_P00450_CERU_HUMANCeruloplas      IAAVEVEWDYSPQREWEKELHHLQEQ-NVSNAFLDKGEFYIG--------
tr_Q7ZU12Cpprotein_Brachydanio      IAAVEMDWDYSPTRTWEDKMHNGLKE-SPGNEFLKKEGKFIG--------
tr_Q9BQS7Hephaestin_Homosapien      IMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLG--------
tr_Q9Z0Z4Hephaestin_Musmusculu      IMAEEIEWDYCPDRSWELEWHNTSEKDSYGHVFLSNKDGLLG--------
tr_Q804X3CoagulationfactorVIII      IYGENEHD-PRSFQGQIRQYFIAAMEVIWEYGNQRPQHFLKATDPTSGRR
sp_P00451_FA8_HUMANCoagulation      IYDEDENQSPRSFQKKTRHYFIAAVERLWDYGMSSSPHVLRNRAQSG---
tr_Q7TN96FactorVIII_Rattusnorv      IYGEEAGQGPRGFQQKTRHYFIAAVEELWDYGVRVSPGALGDRAWSG---
sp_P12263_FA8_PIGCoagulationfa      IYGEDENQDPRSFQKRTRHYFIAAVEQLWDYGMSESPRALRNRAQNG---
tr_O62730FactorVIII_Canisfamil      IYGDYEDQGLRSFQKKTRHYFIAAVERLWDYGMSRSPHILRNRAQSG---
tr_Q804W6CoagulationfactorVIII      YVLSTDYMDLRSGEVRYPHYYIAAEEVTWDYGVKKPYQLIRPREMSRGMR
sp_Q06194_FA8_MOUSECoagulation      IYSEDIKQGPRSFQQKTRHYFIAAVERLWDYGMSTSHVLRNRYQSDN---
tr_Q7TPK2Ac2_120_Rattusnorvegi      PDTIAAWYLRSFG-GNKKFYYIAAEEISWDYSKFAPSEMDNEETDNT---
tr_O88783Murinecoagulationfact      PDTIAAWYLRGHG-GHKKFYYIAAEEITWNYAEFAQSEMDHEDTGHT---
sp_Q28107_FA5_BOVINCoagulation      PDNIAAWYLRSNT-GNRKYYYIAAEEISWDYSKFVQ----SDDVDYV---
tr_Q804X4CoagulationfactorVpre      PDNIAEHYLRSR--GNERRYYIAAKEVCWNYAGLKKS---TMMYDKI---
sp_Q9GLP1_FA5_PIGCoagulationfa      PDNIAAWYLRSNN-GNRRNYYIAAEELSWDYSKFTQ----REDIDDV---
sp_P12259_FA5_HUMANCoagulation      PDNIAAWYLRSNN-GNRRNYYIAAEEISWDYSEFVQRETDIEDSDDI---
tr_Q7SZN0PseutarinCprecursor_P      PDDIAGRYLRTINRGNKRRYYIAAEEVLWDYSPIGKS-----QVRSR---
tr_Q804W5CoagulationfactorVpre      LHLHQTRKYLENRDKDVRTYFIAAEEVQWDYAGYGQRR--RERPGQN---
tr_Q90X47SC_bZ20I5.3_Novelprot      LDATSQHLLKMAGDKNTRTYFISVEEEEWDYAGYGQRR--LDKTAQN---
                                                        .    :                        

sp_Q61147_CERU_MOUSECeruloplas      ---SKYKKVVYRQFTDSSFREQVKRRAEEDEHLGILGPPIHANVGDKVKV
sp_P00450_CERU_HUMANCeruloplas      ---SKYKKVVYRQYTDSTFRVPVERKAEE-EHLGILGPQLHADVGDKVKI
tr_Q7ZU12Cpprotein_Brachydanio      ---SKYKKVLYKEYTDETFTKLKERTADM-EHLGIMGPMIHGKVGEKVKI
tr_Q9BQS7Hephaestin_Homosapien      ---SRYKKAVFREYTDGTFRIPRPRTGPE-EHLGILGPLIKGEVGDILTV
tr_Q9Z0Z4Hephaestin_Musmusculu      ---SKYKKAVFREYTDGTFRIPRPRSGPE-EHLGILGPLIRGEVGDILTV
tr_Q804X3CoagulationfactorVIII      KPFRQYRKVIFREYLDGSFTQPAMRGELD-EHLGILGPYIRAEIEDTIMV
sp_P00451_FA8_HUMANCoagulation      -SVPQFKKVVFQEFTDGSFTQPLYRGELN-EHLGLLGPYIRAEVEDNIMV
tr_Q7TN96FactorVIII_Rattusnorv      -DAARFRKVVFREFTDGSFTQRVHRGELD-AHLGLLGPYIRAEVEDNIVV
sp_P12263_FA8_PIGCoagulationfa      -EVPRFKKVVFREFADGSFTQPSYRGELN-KHLGLLGPYIRAEVEDNIMV
tr_O62730FactorVIII_Canisfamil      -DVQQFKKVVFQEFTDGSFTQPLYRGELN-EHLGLLGPYIRAEVEDNIVV
tr_Q804W6CoagulationfactorVIII      KFLPQYKKVVYRAYKDESFRDPVSQGELE-AHLGILGPFIKAEVNDLLTV
sp_Q06194_FA8_MOUSECoagulation      --VPQFKKVVFQEFTDGSFSQPLYRGELN-EHLGLLGPYIRAEVEDNIMV
tr_Q7TPK2Ac2_120_Rattusnorvegi      PKDTTYKKVVFRKYLDSTFTSRDPQGEYE-EHLGILGPVIRAEVDDVIQV
tr_O88783Murinecoagulationfact      PKDTTYKKVVFRKYLDSTFTSRDPRAEYE-EHLGILGPVIRAEVDDVIQV
sp_Q28107_FA5_BOVINCoagulation      PEDTVYKKVVFRKYLDSTFTKLDPQGEYE-EHLGILGPVIRAEVDDVIQV
tr_Q804X4CoagulationfactorVpre      CKDGSTKKVIFQRYTDSTFTTVQDEGEYE-EHLGILGPVIRAEVNDVILV
sp_Q9GLP1_FA5_PIGCoagulationfa      PEHTIYKKVVFRKYLDSTFTKLDPRGEYE-EHLGILGPIIRAEVDDVIQV
sp_P12259_FA5_HUMANCoagulation      PEDTTYKKVVFRKYLDSTFTKRDPRGEYE-EHLGILGPIIRAEVDDVIQV
tr_Q7SZN0PseutarinCprecursor_P      AAKTTFKKAIFRSYLDDTFQTPSTGGEYE-KHLGILGPIIRAEVDDVIEI
tr_Q804W5CoagulationfactorVpre      IRHTKFIKVVFRLYLDSSFRTPEVRGEVD-EHLGILGPVIKAEVGQTIMV
tr_Q90X47SC_bZ20I5.3_Novelprot      ERPTVFRKVVFRRYLDSTFSIRDIRGEMD-EHLGILGPLIKAEVDQTVMV
                                           *.::: : * :*            ***::** ::..: : : :

sp_Q61147_CERU_MOUSECeruloplas      VFKNMATRPYSIHAHGVKTESSTVV--------------PTL-PGEVATY
sp_P00450_CERU_HUMANCeruloplas      IFKNMATRPYSIHAHGVQTESSTVT--------------PTL-PGETLTY
tr_Q7ZU12Cpprotein_Brachydanio      VFKNMARRPYSIHAHGVKTDSPQVP--------------LTR-PGETQTY
tr_Q9BQS7Hephaestin_Homosapien      VFKNNASRPYSVHAHGVLESTTVWP--------------LAAEPGEVVTY
tr_Q9Z0Z4Hephaestin_Musmusculu      VFKNKASRPYSIHAHGVLESNTGGP--------------QAAEPGEVLTY
tr_Q804X3CoagulationfactorVIII      KFKNLASRPFSFHSSLQGYEELHGG--------------EAVQPGEVREY
sp_P00451_FA8_HUMANCoagulation      TFRNQASRPYSFYSSLISYEEDQRQG--------AEPRKNFVKPNETKTY
tr_Q7TN96FactorVIII_Rattusnorv      TFRNQASRPYSFYSSLVSYPEADGG---------AAPRSNFVRPNETKTY
sp_P12263_FA8_PIGCoagulationfa      TFKNQASRPYSFYSSLISYPDDQEQG--------AEPRHNFVQPNETRTY
tr_O62730FactorVIII_Canisfamil      TFKNQASRPYSFYSSLISYDEDEGQG--------AEPRRKFVNPNETKIY
tr_Q804W6CoagulationfactorVIII      VFKNNASRPYSFH--LHGVYDRNQGA--------SGVLGKPLAPGEVQTY
sp_Q06194_FA8_MOUSECoagulation      TFKNQASRPYSFYSSLISYKEDQRG---------EEPRRNFVKPNETKIY
tr_Q7TPK2Ac2_120_Rattusnorvegi      RFKNLASRPYSLHAHGLSYEKSSEGKNYEDDSPKWFQEDDAVQPNSSYTY
tr_O88783Murinecoagulationfact      RFKNLASRPYSLHAHGLSYEKSSEGKTYEDESPEWFQEDDAVQPNSSYTY
sp_Q28107_FA5_BOVINCoagulation      RFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAIQPNKTYTY
tr_Q804X4CoagulationfactorVpre      HFKNLASRPYSLHAHGLFYEKSSEGSIYDDESSDWFKEDDKVQPNSSYIY
sp_Q9GLP1_FA5_PIGCoagulationfa      RFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTY
sp_P12259_FA5_HUMANCoagulation      RFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTY
tr_Q7SZN0PseutarinCprecursor_P      QFKNLASRPYSLHAHGLLYEKSSEGRSYDDKSPELFKKDDAIMPNGTYTY
tr_Q804W5CoagulationfactorVpre      VFKNNASRPFSLHPNGVSYSKQTEGLSYEDGSNYWYKYDNEVQPGATFTY
tr_Q90X47SC_bZ20I5.3_Novelprot      FFRNRASRPYSLHANGVKYLKQMEGLSYDDESPYWYKQDDAVPPNGTFTY
                                     *:* * **:*.:                              *.    *

sp_Q61147_CERU_MOUSECeruloplas      TWQIPERSGAGREDSACIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKV
sp_P00450_CERU_HUMANCeruloplas      VWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYLKV
tr_Q7ZU12Cpprotein_Brachydanio      TWYLPKNSGPTEEQEECSVGAYYSTVDVIKDMYSGLVGPLVICKKSLART
tr_Q9BQS7Hephaestin_Homosapien      QWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEP
tr_Q9Z0Z4Hephaestin_Musmusculu      QWNIPERSGPGPSDSACVSWIYYSAVDPIKDMYSGLVGPLVICRNGILEP
tr_Q804X3CoagulationfactorVIII      SWKVLSQMAPTMQEFDCKAWAYLSNVDLEKDLHSGLIGPLIICRRGVLNS
sp_P00451_FA8_HUMANCoagulation      FWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVCHTNTLNP
tr_Q7TN96FactorVIII_Rattusnorv      FWRVRPHMAPTDGEFDCKAWAYFSDVDLERDLHSGLIGPLLVCHASTLHP
sp_P12263_FA8_PIGCoagulationfa      FWKVQHHMAPTEDEFDCKAWAYFSDVDLEKDVHSGLIGPLLICRANTLNA
tr_O62730FactorVIII_Canisfamil      FWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLICRSNTLNP
tr_Q804W6CoagulationfactorVIII      NWRITKTQGPMDSEFDCKTGTYYSTVDKERDLNSGLIGPLVICKPGTLST
sp_Q06194_FA8_MOUSECoagulation      FWKVQHHMAPTEDEFDCKAWAYFSDVDLERDMHSGLIGPLLICHANTLNP
tr_Q7TPK2Ac2_120_Rattusnorvegi      VWHATERAGPENPGSACRAWVYYSAVDVERDIHSGLIGPLLICRKGTLDR
tr_O88783Murinecoagulationfact      VWHATKRSGPENPGSACRAWAYYSAVNVERDIHSGLIGPLLICRKGTLHM
sp_Q28107_FA5_BOVINCoagulation      VWHATTRSGPENPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLDK
tr_Q804X4CoagulationfactorVpre      VWYANRRSGPLQPGAACRSWVYYSDVNLEKDTHSGLIGPILICEKGTFSA
sp_Q9GLP1_FA5_PIGCoagulationfa      VWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLHK
sp_P12259_FA5_HUMANCoagulation      VWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICQKGILHK
tr_Q7SZN0PseutarinCprecursor_P      VWQVPPRSGPTDNTEKCKSWAYYSGVNPEKDIHSGLIGPILICQKGMIDK
tr_Q804W5CoagulationfactorVpre      IWNVNPMVGPTSDESNCRTWAYYSGVNPERDIHSGLIGPLLVCQKGTLNQ
tr_Q90X47SC_bZ20I5.3_Novelprot      MWTINPKSGPQNNESDCRTWTYYSAVNPERDINSGLIGPLLVCRKGTLDK
                                     *      ..      *    * * *:  :*  ***:**: :*.      

sp_Q61147_CERU_MOUSECeruloplas      FSPKKK--MEFFLLFLVFDENESWYLDDNIKTYSEH-PEKVNKDNEEFLE
sp_P00450_CERU_HUMANCeruloplas      FNPRRK--LEFALLFLVFDENESWYLDDNIKTYSDH-PEKVNKDDEEFIE
tr_Q7ZU12Cpprotein_Brachydanio      LGLKKEV-EEFALLFMVFDENESWYLEENIKTHVKN-PPKALTEDQQFIE
tr_Q9BQS7Hephaestin_Homosapien      HGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLE
tr_Q9Z0Z4Hephaestin_Musmusculu      NGGRNDMDREFALLFLIFDENQSWYLKENIATYGPQESSHVNLKDATFLE
tr_Q804X3CoagulationfactorVIII      AFKRQLAVQEFSLLFTIFDETKSWYFPENMRRNCRP-PCRIQLDNPDFRR
sp_P00451_FA8_HUMANCoagulation      AHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRA-PCNIQMEDPTFKE
tr_Q7TN96FactorVIII_Rattusnorv      SHARPLAVQEFALLFAVFDETKSWYCAENLDRKCRP-PRGTPAGDPAWRE
sp_P12263_FA8_PIGCoagulationfa      AHGRQVTVQEFALFFTIFDETKSWYFTENVERNCRA-PCHLQMEDPTLKE
tr_O62730FactorVIII_Canisfamil      AHGRQVTVQEFALVFTIFDETKSWYFTENLERNCRA-PCNVQKEDPTLKE
tr_Q804W6CoagulationfactorVIII      RLHTQPDVQEFALLFHTFDETKSWYMEENLRRYCAP-PCHANTQDPWYHI
sp_Q06194_FA8_MOUSECoagulation      AHGRQVSVQEFALLFTIFDETKSWYFTENVKRNCKT-PCNFQMEDPTLKE
tr_Q7TPK2Ac2_120_Rattusnorvegi      ASNLPLDMREFVLLFMVFDEKKSWYYEK-SKGSWR-------IESPEAKN
tr_O88783Murinecoagulationfact      ERNLPMDMREFVLLFMVFDEKKSWYYEK-SKGSRR-------IESPEEKN
sp_Q28107_FA5_BOVINCoagulation      ETNMPVDMREFVLLFMVFDEKKSWYYDKKPTRSWR-------RASSEVKN
tr_Q804X4CoagulationfactorVpre      SDNNRTNTRDFFLLFMVFDEEESWYFDKRSRKPCT-------EKTQEMQQ
sp_Q9GLP1_FA5_PIGCoagulationfa      ENNMPVDMREFVLLFMVFDEKKSWYYEKKFTRSWR-------LTSSEVKN
sp_P12259_FA5_HUMANCoagulation      DSNMPVDMREFVLLFMTFDEKKSWYYEKKSRSSWR-------LTSSEMKK
tr_Q7SZN0PseutarinCprecursor_P      YN-RTIDIREFVLFFMVFDEEKSWYFPKSDKSTCE-------EKLIGVQS
tr_Q804W5CoagulationfactorVpre      EL---TNTREFMLLFMTFDESQSWYFDRNREIMLRR--SWRKVMDPDIME
tr_Q90X47SC_bZ20I5.3_Novelprot      KP---EDRREFVLLFMTFDENKSWLYEENRQRIERK--NRRVVMDPNFQD
                                             :* *.*  *** :**                          

sp_Q61147_CERU_MOUSECeruloplas      SNKMHAINGKMFGNLQGLTMHVKDEVNWYLMGMGNEIDLHTVHFHGHSFQ
sp_P00450_CERU_HUMANCeruloplas      SNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQ
tr_Q7ZU12Cpprotein_Brachydanio      SNKMHGINGLVFGNLKGLNMKVGDKVYWYLMGLGNEVDIHTAHFHGHSFD
tr_Q9BQS7Hephaestin_Homosapien      SNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFL
tr_Q9Z0Z4Hephaestin_Musmusculu      SNKMHAINGKLYANLRGLTVYQGERVAWYMLAMGQDTDIHTVHFHAESFL
tr_Q804X3CoagulationfactorVIII      NHSFHAINGYVGDTLPGLVMAQQQRIRWHLLNMGSTEDIHSVHFHGQMFS
sp_P00451_FA8_HUMANCoagulation      NYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFT
tr_Q7TN96FactorVIII_Rattusnorv      EYRFHAVNGYVADALLGLVMAEGRRTRWHLLSMGDPGHAQSVHFSAHSVT
sp_P12263_FA8_PIGCoagulationfa      NYRFHAINGYVMDTLPGLVMAQNQRIRWYLLSMGSNENIHSIHFSGHVFS
tr_O62730FactorVIII_Canisfamil      NFRFHAINGYVKDTLPGLVMAQDQKVRWYLLSMGSNENIHSIHFSGHVFT
tr_Q804W6CoagulationfactorVIII      SNKFAAINGYVAESLPGLLVAQHQRVRWHLLNVGSDGEYHAVHFHGLPFT
sp_Q06194_FA8_MOUSECoagulation      NYRFHAINGYVMDTLPGLVMAQDQRIRWYLLSMGNNENIQSIHFSGHVFT
tr_Q7TPK2Ac2_120_Rattusnorvegi      SHEFYAINGMIYN-LPGLRMYEQEWVRLYLLNMGGPQDIHVVHFHGQILL
tr_O88783Murinecoagulationfact      AHKFYAINGMIYN-LPGLRMYEQEWVRLHLLNMGGSRDIHVVHFHGQTLL
sp_Q28107_FA5_BOVINCoagulation      SHEFHAINGMIYN-LPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLL
tr_Q804X4CoagulationfactorVpre      CHKFYAINGITNN-LQGLRMYEGELVRWHLLNMGVPKDIHVVHFHGQTFI
sp_Q9GLP1_FA5_PIGCoagulationfa      SHKFHAINGMIYN-LPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLL
sp_P12259_FA5_HUMANCoagulation      SHEFHAINGMIYS-LPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLL
tr_Q7SZN0PseutarinCprecursor_P      LHTFPAINGIPYQ-LQGLTMYKDENVHWHLLNMGGPKDIHVVNFHGQTFT
tr_Q804W5CoagulationfactorVpre      NLKFHSINGIIYN-LKGLRMYTNQLVSWHLINMGSPKDFNSVHFHGQTFL
tr_Q90X47SC_bZ20I5.3_Novelprot      NLKFDAINGIIYS-LKGLRMYTNQLAKWHLINMGSPKDLHSVHFHGQTFI
                                       : .:**     * ** :        ::: :*   . :  :* .  . 

sp_Q61147_CERU_MOUSECeruloplas      Y-KHRGVYSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHVHAGMATT
sp_P00450_CERU_HUMANCeruloplas      Y-KHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETT
tr_Q7ZU12Cpprotein_Brachydanio      Y-KVSGTHRADVFDLVPGTFQTVTMRPLYSGTWLLHCHVTDHIQAGMETT
tr_Q9BQS7Hephaestin_Homosapien      Y-RNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETL
tr_Q9Z0Z4Hephaestin_Musmusculu      Y-QNGQSYRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETI
tr_Q804X3CoagulationfactorVIII      I-RTSQEYRMGVYNLYPGVFGTVEMQPSHAGIWQVECKVGEHLQAGMSAL
sp_P00451_FA8_HUMANCoagulation      V-RKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTL
tr_Q7TN96FactorVIII_Rattusnorv      V-RDGGEHRTAVCNLYPGVFTTVEMLPSRAGIWRVESLVGEHLRAGMSAL
sp_P12263_FA8_PIGCoagulationfa      V-RKKEEYKMAVYNLYPGVFETVEMLPSKVGIWRIECLIGEHLQAGMSTT
tr_O62730FactorVIII_Canisfamil      V-RKKEEYKMAVYNLYPGVFETVEMLPSQVGIWRIECLIGEHLQAGMSTL
tr_Q804W6CoagulationfactorVIII      V-HAKKEHRMGVYNLFPGVFGTVEMRPPTVGTWLVECTVGESQLAGMRAK
sp_Q06194_FA8_MOUSECoagulation      V-RKKEEYKMAVYNLYPGVFETLEMIPSRAGIWRVECLIGEHLQAGMSTL
tr_Q7TPK2Ac2_120_Rattusnorvegi      D-NRTKQHHLGVWPLLP---------------------------------
tr_O88783Murinecoagulationfact      D-NRTKQHQLGVWPLLPGSFKTLEMKASKPGWWLLDTEVGENQVAGMQTP
sp_Q28107_FA5_BOVINCoagulation      E-NGTQQHQLGVWPLLPGSFKTLEMKASKPGWWLLDTEVGEIQRAGMQTP
tr_Q804X4CoagulationfactorVpre      E-QLEAKYQLGTYTLLPGSFQTVEMKPQRPGWWLLDTEVGEYQQAGMQAS
sp_Q9GLP1_FA5_PIGCoagulationfa      E-NGTQQHQLGVWPLLPGSFKTLEMKTSKAGWWLLDTEVGENQRAGMQTP
sp_P12259_FA5_HUMANCoagulation      E-NGNKQHQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTP
tr_Q7SZN0PseutarinCprecursor_P      E-EGREDNQLGVLPLLPGTFASIKMKPSKIGTWLLETEVGENQERGMQAL
tr_Q804W5CoagulationfactorVpre      HKKKTTSYRQAVYPLLPGSFATLEMYPSKPGLWQLETEVGINQEKGMQTL
tr_Q90X47SC_bZ20I5.3_Novelprot      N-KELKDHRQGVYPLLPGGFATLEMLPSKPGLWQLESEVGLSQQRGMQTL
                                      .           : *                                 

sp_Q61147_CERU_MOUSECeruloplas      YTVL-----------------------------PVEQETKSG--------
sp_P00450_CERU_HUMANCeruloplas      YTVL-----------------------------QNE-DTKSG--------
tr_Q7ZU12Cpprotein_Brachydanio      YTVL------------------------------EKDGRKRGFLGIFGSG
tr_Q9BQS7Hephaestin_Homosapien      FTVF------------------SRTEHLSPLTVITKETEKAVPPRDIEEG
tr_Q9Z0Z4Hephaestin_Musmusculu      FTVL------------------SHEEHYSTMTTITKEIGKAVILRDIGGD
tr_Q804X3CoagulationfactorVIII      FLVY------------------NQDCQNALGMASGYIADSQITASGQEGP
sp_P00451_FA8_HUMANCoagulation      FLVY------------------SNKCQTPLGMASGHIRDFQITASGQYGQ
tr_Q7TN96FactorVIII_Rattusnorv      FLVY------------------STRCQVPLGMASGYIRDSQITASGYHGL
sp_P12263_FA8_PIGCoagulationfa      FLVY------------------SKECQAPLGMASGRIRDFQITASGQYGQ
tr_O62730FactorVIII_Canisfamil      FLVY------------------SKKCQTPLGMASGHIRDFQITASGQYGQ
tr_Q804W6CoagulationfactorVIII      LLVY------------------NPQCSRPLGMKSGRIGDSQIKASDYIGN
sp_Q06194_FA8_MOUSECoagulation      FLVY------------------SKQCQIPLGMASGSIRDFQITASGHYGQ
tr_Q7TPK2Ac2_120_Rattusnorvegi      ------------------------ECKMPMGLSTGAISDSQIKASEYLSC
tr_O88783Murinecoagulationfact      FLI------------------IDKECKMPMGLSTGVISDSQIKASEYLTY
sp_Q28107_FA5_BOVINCoagulation      FLI------------------VDRECKMPMGLSTGLIADSQIQASEFWGY
tr_Q804X4CoagulationfactorVpre      YLV------------------LEKGCRIPMGMASGVILDSQINASHHIDY
sp_Q9GLP1_FA5_PIGCoagulationfa      FLI------------------IDRECKMPMGLSTGLIADSQIKASEFWGH
sp_P12259_FA5_HUMANCoagulation      FLI------------------MDRDCRMPMGLSTGIISDSQIKASEFLGY
tr_Q7SZN0PseutarinCprecursor_P      FTV------------------IDKDCKLPMGLASGIIQDSQISASGHVGY
tr_Q804W5CoagulationfactorVpre      FLVLADD------------------CYHPLGLESGSVKNDQITAINTRGY
tr_Q90X47SC_bZ20I5.3_Novelprot      FLFDESYKKYRVCQVLRSYLIYFAVCDHPLGLISGTVQDEQITASDTRGQ
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      NVKMLGMQIPIKNVEMLA------SVLVAISVTLLLVVLALGGVVWYQHR
tr_Q9Z0Z4Hephaestin_Musmusculu      NVKMLGMNIPIKDVEILS------SALIAICVLLLLIALALGGVVWYQHR
tr_Q804X3CoagulationfactorVIII      WAPKLARLHNSGSINAWS------TGESNPWIQVDLLHLKIIHGIKTQGA
sp_P00451_FA8_HUMANCoagulation      WAPKLARLHYSGSINAWS------TKEPFSWIKVDLLAPMIIHGIKTQGA
tr_Q7TN96FactorVIII_Rattusnorv      WTPQLARLHNAGSVNAWS------AKEPFAWIKVDLLAPMILHGIETQGA
sp_P12263_FA8_PIGCoagulationfa      WAPKLARLHYSGSINAWS------TKDPHSWIKVDLLAPMIIHGIMTQGA
tr_O62730FactorVIII_Canisfamil      WAPKLARLHYSGSINAWS------TKDPFSWIKVDLLAPMIIHGIMTQGA
tr_Q804W6CoagulationfactorVIII      WLPHLARLDQSGYINAWM------GYNEKSWIQVDLQAPTLLHRVQTQGV
sp_Q06194_FA8_MOUSECoagulation      WAPNLARLHYSGSINAWS------TKEPFSWIKVDLLAPMIVHGIKTQGA
tr_Q7TPK2Ac2_120_Rattusnorvegi      LGGHARGLTDP-VWYSMSPDKIPRSFLIP---------------------
tr_O88783Murinecoagulationfact      WEPRLARLNNAGSYNAWSIEKTALDFPIKPWIQVDMQKEVVVTGIQTQGA
sp_Q28107_FA5_BOVINCoagulation      WEPKLARLNNGGSYNAWIAEKLSTEFNPEPWIQVDMQKEVLLTGIQTQGA
tr_Q804X4CoagulationfactorVpre      WEPKLARLNNSGTYNAWSTTMT----EDLPWIQVDFQRQVLLTGIQTQGA
sp_Q9GLP1_FA5_PIGCoagulationfa      WQPKLARLNNGGSYNAWITDKFSGESNSKPWIQVDMQREVVFTGIQTQGA
sp_P12259_FA5_HUMANCoagulation      WEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGA
tr_Q7SZN0PseutarinCprecursor_P      WEPKLARLNNTGKYNAWS---IIKKEHEHPWIQIDLQRQVVITGIQTQGT
tr_Q804W5CoagulationfactorVpre      WEPHLARLHNQGKYNAWS-----TDQN-YSWIQVDFQRPVVISQVATQGA
tr_Q90X47SC_bZ20I5.3_Novelprot      WYPHLARLHNTGKYNAWS-----TSSEPGQYLQVDFQRPVVISKVATQGA
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      QRKLRRNRRSILDDSFKLLSFKQ---------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      QRKLRRNRRSILDDSFKLLSLKQ---------------------------
tr_Q804X3CoagulationfactorVIII      RQKLSSLYVSQFIVFYSLHGQRWKKYKGN--------------TTSTQMM
sp_P00451_FA8_HUMANCoagulation      RQKFSSLYISQFIIMYSLDGKKWQTYRGN--------------STGTLMV
tr_Q7TN96FactorVIII_Rattusnorv      RHRLSSLYVSQFIIMYSLDGKQWLSYRGN--------------STGSLMV
sp_P12263_FA8_PIGCoagulationfa      RQKFSSLYISQFIIMYSLDGRNWQSYRGN--------------STGTLMV
tr_O62730FactorVIII_Canisfamil      RQKFSSLYVSQFIIMYSLDGNKWHSYRGN--------------STGTLMV
tr_Q804W6CoagulationfactorVIII      RSNLRNNYITAFTVSYSLDQETWSTYRGSGSS--------RSSSSSTAKV
sp_Q06194_FA8_MOUSECoagulation      RQKFSSLYISQFIIMYSLDGKKWLSYQGN--------------STGTLMV
tr_Q7TPK2Ac2_120_Rattusnorvegi      RLLPKEKYSNAESLSVIIVQTTLSLF------------------LLVLYS
tr_O88783Murinecoagulationfact      KHYLKSCFTTEFQVAYSSDQTNWQIFRGKS--------------GKSVMY
sp_Q28107_FA5_BOVINCoagulation      KHYLKPYYTTEFCVAYSLDRKNWRIFKGNS--------------TRNVMY
tr_Q804X4CoagulationfactorVpre      KHFLKSFYVQKLFIVYSTDKRKWNTFRGDS--------------SPAEKI
sp_Q9GLP1_FA5_PIGCoagulationfa      KYYLKSYYTTEFNVAYSSDQRNWRIFKGNS--------------TKNVMY
sp_P12259_FA5_HUMANCoagulation      KHYLKSCYTTEFYVAYSSNQINWQIFKGNS--------------TRNVMY
tr_Q7SZN0PseutarinCprecursor_P      VQLLQHSYTVEYFVTYSEDGQNWITFKGRH--------------SETQMH
tr_Q804W5CoagulationfactorVpre      KQFFQAQYVSSYYISYSNDRRSWSFYKGDS--------------RDDIKV
tr_Q90X47SC_bZ20I5.3_Novelprot      KQFLTHNFVLNYTISYSTDKKKWIYYKGDSDAVRKANIHKTNVFFNARQT
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      FFANVDATTVKENRFNPPIIARYIRINPTHDSIRTTLRMELIGCDLNSCS
sp_P00451_FA8_HUMANCoagulation      FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCS
tr_Q7TN96FactorVIII_Rattusnorv      FFGNVDASTVRHNRFDPPIVARYIRVHPTHASIRTALRMELLGCDLNSCS
sp_P12263_FA8_PIGCoagulationfa      FFGNVDASGIKHNIFNPPIVARYIRLHPTHYSIRSTLRMELMGCDLNSCS
tr_O62730FactorVIII_Canisfamil      FFGNVDSSGIKHNIFNPPIIAQYIRLHPTHYSIRSTLRMELLGCDFNSCS
tr_Q804W6CoagulationfactorVIII      FNGNLDNSRVKNNPFVPPFVARYIRIHPLYYNQRPALRMELLGCDLNSCS
sp_Q06194_FA8_MOUSECoagulation      FFGNVDSSGIKHNSFNPPIIARYIRLHPTHSSIRSTLRMELMGCDLNSCS
tr_Q7TPK2Ac2_120_Rattusnorvegi      FAGNSDASTIKENRFDPPIVARYIRIHPTKSYNRPTLRLELLGCEVNGCS
tr_O88783Murinecoagulationfact      FTGNSDGSTIKENRLDPPIVARYIRIHPTKSYNRPTLRLELQGCEVNGCS
sp_Q28107_FA5_BOVINCoagulation      FGGNSDASTIKENQIDPPVVARYIRISPTGSYNKPALRLELQGCEVNGCS
tr_Q804X4CoagulationfactorVpre      FEGNSDAYGIKENIIDPPIIARYIRVYPKQAYNEPTLRMELLGCEVDACS
sp_Q9GLP1_FA5_PIGCoagulationfa      FNGNSDASTITENQFDPPVVARYIRISPTESYNKPALRLELQGCEVNGCS
sp_P12259_FA5_HUMANCoagulation      FNGNSDASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCEVNGCS
tr_Q7SZN0PseutarinCprecursor_P      FEGNSDGTTVKENHIDPPIIARYIRLHPTKFYNRPTFRIELLGCEVEGCS
tr_Q804W5CoagulationfactorVpre      FTGNNNPYDVKKNTFFPPLIGRFIRFHPLKWYNKATLRMDFYGCELDGCS
tr_Q90X47SC_bZ20I5.3_Novelprot      FEGNAEAYETKENIFFPPLIGRYVRLHPLHSYNFPTVRLEYYGCELDGCS
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      MPLGMESKGIPDQRISASSYSSNIFS-SWSPSQARLNLQGRTNAWRPETN
sp_P00451_FA8_HUMANCoagulation      MPLGMESKAISDAQITASSYFTNMFA-TWSPSKARLHLQGRSNAWRPQVN
tr_Q7TN96FactorVIII_Rattusnorv      APLGMESGWISDTQVTASSHLSTTFS-AWPPALARLHLRGGANAWRPQVN
sp_P12263_FA8_PIGCoagulationfa      MPLGMQNKAISDSQITASSHLSNIFA-TWSPSQARLHLQGRTNAWRPRVS
tr_O62730FactorVIII_Canisfamil      MPLGMESKAISDAQITASSYLSSMLA-TWSPSQARLHLQGRTNAWRPQAN
tr_Q804W6CoagulationfactorVIII      LPLGLQDRRIPDESFVASSSYWSLLR-SWTPSLARLHQEGSANAWRPKNN
sp_Q06194_FA8_MOUSECoagulation      IPLGMESKVISDTQITASSYFTNMFA-TWSPSQARLHLQGRTNAWRPQVN
tr_Q7TPK2Ac2_120_Rattusnorvegi      TPLGLEDGRIQNKQITASSFKKSWWGSYWEPSLARLNAQGRVNAWQAKAN
tr_O88783Murinecoagulationfact      TPLGLEDGRIQDKQITASSFKKSWWGDYWEPSLARLNAQGRVNAWQAKAN
sp_Q28107_FA5_BOVINCoagulation      TPLGMESGKIENKQITASSFKKSWWGNYWEPFLARLNAQGRVNAWQAKAN
tr_Q804X4CoagulationfactorVpre      LPLGMENGEIKNTQITASSVRTSWFS-TWEPSLARINQKGKINAWRAESN
sp_Q9GLP1_FA5_PIGCoagulationfa      TPLGMESGNIKNEQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKAN
sp_P12259_FA5_HUMANCoagulation      TPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKAN
tr_Q7SZN0PseutarinCprecursor_P      VPLGMESGAIKNSEITASSYKKTWWS-SWEPSLARLNLEGGTNAWQPEVN
tr_Q804W5CoagulationfactorVpre      VPLGMESGLIEDHQITASSTASKWYSGTWRPFLGRLNKEGTINAWQAKYN
tr_Q90X47SC_bZ20I5.3_Novelprot      VPLGMEKGLIDDSKITASSVASNWYSGQWHPWYARLNKQGTANAWQAKNN
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      SPSEWLQVDFEATKKVTAIITQGAKAVFTHMFVKEFAVSSNQDGVHWSRV
sp_P00451_FA8_HUMANCoagulation      NPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF
tr_Q7TN96FactorVIII_Rattusnorv      DPTQWLQVDLQRTVKVTGVVTQGARSLLTAMFVKKFLVSTSQDGRHWTHV
sp_P12263_FA8_PIGCoagulationfa      SAEEWLQVDLQKTVKVTGITTQGVKSLLSSMYVKEFLVSSSQDGRRWTLF
tr_O62730FactorVIII_Canisfamil      NPKEWLQVDFRKTMKVTGITTQGVKSLLISMYVKEFLISSSQDGHNWTLF
tr_Q804W6CoagulationfactorVIII      NPHEWLQVDLGKVKRITGVVTQGARSLLTKMMVTEFSVTISRDGQAWSSV
sp_Q06194_FA8_MOUSECoagulation      DPKQWLQVDLQKTMKVTGIITQGVKSLFTSMFVKEFLISSSQDGHHWTQI
tr_Q7TPK2Ac2_120_Rattusnorvegi      NNKQWLQIDLLKIKKVTAIVTQGCKSLSSEMYVKSYSILYSDQGVSWKPY
tr_O88783Murinecoagulationfact      NNKQWLQVDLLKIKKVTAIVTQGCKSLSSEMYVKSYSIQYSDQGVAWKPY
sp_Q28107_FA5_BOVINCoagulation      NNNQWLQIDLLKIKKITAIVTQGCKSLSSEMYVKSYTIHYSDQGTDWKPY
tr_Q804X4CoagulationfactorVpre      NNQQWLQIDLLTIKKITAIATQGVKSVTTENFVKTYVILYSNQGSEWKSY
sp_Q9GLP1_FA5_PIGCoagulationfa      NNNQWLQIDLLKIKKITAITTQGCKSLSSEMYVKRYTIQYSDRGVEWKSY
sp_P12259_FA5_HUMANCoagulation      NNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPY
tr_Q7SZN0PseutarinCprecursor_P      NKDQWLQIDLQHLTKITSIITQGATSMTTSMYVKTFSIHYTDDNSTWKPY
tr_Q804W5CoagulationfactorVpre      DMDQWLQVELTQVKKITGIVTQGAKFLGAEMFVTSFSLQYSHDGINWHPY
tr_Q90X47SC_bZ20I5.3_Novelprot      DIQPWIQVELKEVKKITGIVTQGAKSMGNEMFVRSYILEYSEDGRRWMKY
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      --------------------------------------------------
sp_P00450_CERU_HUMANCeruloplas      --------------------------------------------------
tr_Q7ZU12Cpprotein_Brachydanio      --------------------------------------------------
tr_Q9BQS7Hephaestin_Homosapien      --------------------------------------------------
tr_Q9Z0Z4Hephaestin_Musmusculu      --------------------------------------------------
tr_Q804X3CoagulationfactorVIII      LHNG--KEKIFRANRDYTSTVLNSLEPPLFARYVRIHPRHWHNHIALRIE
sp_P00451_FA8_HUMANCoagulation      FQNG--KVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRME
tr_Q7TN96FactorVIII_Rattusnorv      LQDG--KVKVFQGNRDASTPMVNSLHPPRFTRYLRIHPQVWERQIALRLE
sp_P12263_FA8_PIGCoagulationfa      LQDG--HTKVFQGNQDSSTPVVNALDPPLFTRYLRIHPTSWAQHIALRLE
tr_O62730FactorVIII_Canisfamil      LQND--KVKVFQGNRDSSTPVRNALEPPLVARYVRLHPQSWAHHIALRLE
tr_Q804W6CoagulationfactorVIII      LEGSSQREKIFQGNNDSDEEALTIFDAPLFGRYIRIHPLGWINDIALRLE
sp_Q06194_FA8_MOUSECoagulation      LYNG--KVKVFQGNQDSSTPMMNSLDPPLLTRYLRIHPQIWEHQIALRLE
tr_Q7TPK2Ac2_120_Rattusnorvegi      RQKSSMVDKIFEGNSNTKGHMKNFFNPPIISRFIRIIPKTWNQSIALRLE
tr_O88783Murinecoagulationfact      RQKSSMVDKIFEGNSNTKGHMKNFFNPPIISRFIRIIPKTWNQSIALRLE
sp_Q28107_FA5_BOVINCoagulation      REKSSMVDKIFEGNNNVRGHVKNFFNPPIISRFIRIIPKTWNQSIALRLE
tr_Q804X4CoagulationfactorVpre      TEDSSSVAKVFSGNEDSRGHVKHFFNPPILSRFIRIVPKTWYNGIALRVE
sp_Q9GLP1_FA5_PIGCoagulationfa      REKSSMVDKIFEGNNNIKGHVKNFFNPPIISRFIRIIPKMWNQSIALRLE
sp_P12259_FA5_HUMANCoagulation      RLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSITLRLE
tr_Q7SZN0PseutarinCprecursor_P      LDVRTSMEKVFTGNINSDGHVKHFFKPPILSRFIRIIPKTWNQYIALRIE
tr_Q804W5CoagulationfactorVpre      TDDDGVPAKIFMGNTNNNDHVKNYMYPPIFSRFIRVIPKSWIGSIPMRME
tr_Q90X47SC_bZ20I5.3_Novelprot      TDDDDYEQKLFQGNTDNNGQIKNYIYPPIFSRFIRIIPKQWQKSVTMRIE
                                                                                      

sp_Q61147_CERU_MOUSECeruloplas      ----------
sp_P00450_CERU_HUMANCeruloplas      ----------
tr_Q7ZU12Cpprotein_Brachydanio      ----------
tr_Q9BQS7Hephaestin_Homosapien      ----------
tr_Q9Z0Z4Hephaestin_Musmusculu      ----------
tr_Q804X3CoagulationfactorVIII      FLGCDTQQEY
sp_P00451_FA8_HUMANCoagulation      VLGCEAQDLY
tr_Q7TN96FactorVIII_Rattusnorv      ILGCEAQQLD
sp_P12263_FA8_PIGCoagulationfa      VLGCEAQDLY
tr_O62730FactorVIII_Canisfamil      VLGCDTQQPA
tr_Q804W6CoagulationfactorVIII      VLGCDTQQAL
sp_Q06194_FA8_MOUSECoagulation      ILGCEAQQQY
tr_Q7TPK2Ac2_120_Rattusnorvegi      LFGCDIY---
tr_O88783Murinecoagulationfact      LFGCDIY---
sp_Q28107_FA5_BOVINCoagulation      LFGCDMY---
tr_Q804X4CoagulationfactorVpre      LFGCDFGGI-
sp_Q9GLP1_FA5_PIGCoagulationfa      LFGCDIY---
sp_P12259_FA5_HUMANCoagulation      LFGCDIY---
tr_Q7SZN0PseutarinCprecursor_P      LFGCEVF---
tr_Q804W5CoagulationfactorVpre      PLGCDCE---
tr_Q90X47SC_bZ20I5.3_Novelprot      LLGCDFE---