CLUSTAL X (1.81) multiple sequence alignment


sp_P81061_CYT_COTJACystatin_Eg      -----------------------------SEG------------------
sp_P01038_CYT_CHICKCystatinpre      --MAGARGCVVLLAA----ALMLVGAVLGSED------------------
sp_O19093_CYTC_SAISCCystatinCp      --MAGPLRAPLLLLA----ILAVALALSPAAGASPG--------------
sp_P21460_CYTC_MOUSECystatinCp      --MASPLRSLLFLLA----VLAVAWAATPKQG------------------
sp_O97862_CYTC_RABITCystatinCp      --MARSLGVPLLLLAA--LVVALALAVSPAAGARTR--------------
sp_P01035_CYTC_BOVINCystatinCp      --MVGSPRAPLLLLASLIVALALALAVSPAAAQGP---------------
sp_P28325_CYTD_HUMANCystatinDp      --MMWPMHTPLLLLT----ALMVAVAGSASAQ------------------
sp_P01036_CYTS_HUMANCystatinSp      --MARPLCTLLLLMA----TLAGALASSSKEE------------------
sp_P19313_CYTS_RATCystatinSpre      --MAYLLHAQLFLLTT--FILVLNMRLCPVLG------------------
tr_Q9JM84DD72protein_Similarto      --MASLLSPSMPVLAA--VALTLTLAVIPEASTNAE--------------
sp_O89098_CYTF_MOUSECystatinFp      ------MWLA-ILLALCCLTSDTHGARPPDFCSKDL--------------
tr_Q7Z4J8CystatinF_Leukocystat      VPTRAAMRAAGTLLAFCCLVLSTTGGPSPDTCSQDL--------------
sp_Q91195_CYT_ONCMYCystatinpre      -----MEWKIVVPLFAVAFTVANAG-------------------------
sp_P35481_CYT_CYPCACystatinpre      -----MYLKVIVLFLAVTLVVESTG-------------------------
sp_P08935_CYT_BITARCystatin_Bi      ------------------IP------------------------------
tn_AAR24527Cystatin_Bitisgabon      MHSRLLVAAPHCLLLLLLLPSALPAL------------------------
sp_P81714_CYT_NAJATCystatin_Fr      ------------------IP------------------------------
tr_Q8VHC1CystatinN_Rattusnorve      ERPHFPLAMGLGLLAFCLLTLSPDARAELRSR------------------
tr_Q9D1B11110017E11Rikprotein_      ERPHFPLAMGLGLLAFCLLTLSPDARAELRSR------------------
sp_Q15828_CYTM_HUMANCystatinMp      ARSNLPLALGLALVAFCLLALPRDARARPQER------------------
tr_P90698Cystatin_Brugiamalayi      --------MFFPIVWLSVLLIISKSFAREIR-------------------
tr_Q9U9A1Cystatin_typecysteine      --------MFYLIIWFSAFAIISKSFAREIR-------------------
sp_P22085_CYTX_ONCVOOnchocysta      ---MLTIKDGTLLIHLLLFSVVALVQLQGAKSARAKNPSKMESKTGE---
tr_Q9NH95Ls_cystatin_Litomosoi      ---MMSVKGVLLVPFLSLFGVVVLVNCLGHG--------NMESEAR----
tr_Q9TYY2K08B4.6protein_Cystat      --------MRFILLIALVFAVLDGINCQIAG-------------------
tr_Q966W0Nippocystatinprecurso      ------MPSAFVLRIALASVVVTSTVSSMVG-------------------
sp_P08934_KNG_RATKininogenprec      IVQTNCSKEDFPSLHEDCVPLPSGDDGECKGNAFVDIHKTIAGFSDSCEF
sp_P01042_KNG_HUMANKininogenpr      IVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLRIASFSQNCDI
sp_O88969_CST8_RATCystatin_rel      --MTKPLLLSLIFFIIPAALAVDVDQSKNEVK------------------
sp_O60676_CST8_HUMANCystatin_r      --MPRCRWLSLILLTIPLALVARKDPKKNETG------------------
tr_Q9DAP11700006C19Rikprotein_      --MAR-FLQTLLFLVIMVEFVSRRVEAWGSPQ------------------
tr_Q8K5A3Cystatin11_Rattusnorv      -MMARLWKTTWFLLAILVALVAFSYQVKRKTFIR----------------
tr_Q7M429Cystatinprecursor_Tac      -------MEGYNILAVLIILVGVSMGQIP---------------------
tr_Q80Y72Cystatin_like1_Musmus      EMKARGLRIPLLLLLVTVVVMAKVNHIQR---------------------
tr_Q8JFU5SI_dZ57F23.1_Novelpro      DIYLLLLVSFLPLFHLSRADQPLEEAVVVARN------------------
tr_Q7M224Cystatin_Perseaameric      --------------------------------------------------
tr_Q84XY6Cystatin_Malusdomesti      -----MMKVPIFALLICLLFVASNGYGGMVGG------------------
                                                                                      

sp_P81061_CYT_COTJACystatin_Eg      ----------RSRLLGAPVPVRENDEGLQRALQFAMAEYN----KAS-ND
sp_P01038_CYT_CHICKCystatinpre      ----------RSRLLGAPVPVDENDEGLQRALQFAMAEYN----RAS-ND
sp_O19093_CYTC_SAISCCystatinCp      ---------RTPRLLGGPMDASVEEEGVRRALDFAVSEYN----KAS-ND
sp_P21460_CYTC_MOUSECystatinCp      -----------PRMLGAPEEADANEEGVRRALDFAVSEYN----KGS-ND
sp_O97862_CYTC_RABITCystatinCp      ---------QSPRLLGGLEDVDAQEKDVQRALGFAESEYN----KGS-ND
sp_P01035_CYTC_BOVINCystatinCp      ---------RKGRLLGGLMEADVNEEGVQEALSFAVSEFN----KRS-ND
sp_P28325_CYTD_HUMANCystatinDp      ----------SRTLAGGIHATDLNDKSVQCALDFAISEYN----KVINKD
sp_P01036_CYTS_HUMANCystatinSp      ----------NRIIPGGIYDADLNDEWVQRALHFAISEYN----KAT-ED
sp_P19313_CYTS_RATCystatinSpre      ------------HFLGGIEKSSMEEEGASEALNYAVNEYN----EKN-SD
tr_Q9JM84DD72protein_Similarto      ---------AKQVVLGGVEPADPKDKEVQKVVKFAVRTYN----DMD-ND
sp_O89098_CYTF_MOUSECystatinFp      ---------ISSVKPGFPKTIETNNPGVLKAARHSVEKFN----NCT-ND
tr_Q7Z4J8CystatinF_Leukocystat      ---------NSRVKPGFPKTIKTNDPGVLQAARYSVEKFN----NCT-ND
sp_Q91195_CYT_ONCMYCystatinpre      -------------LIGGPMDANMNDQGTRDALQFAVVEHN----KKT-ND
sp_P35481_CYT_CYPCACystatinpre      -------------IPGGLVDADINDKDVQKALRFAVDHYN----GQS-ND
sp_P08935_CYT_BITARCystatin_Bi      ---------------GGLSPRDVTDPDVQEAAAFAVEKYN----AGS-KN
tn_AAR24527Cystatin_Bitisgabon      -------------KVGGLYPRDVMDPEVQEAAAFAVENYN----AQS-TN
sp_P81714_CYT_NAJATCystatin_Fr      ---------------GGLSPRSVSDPDVQKAAAFAVQEYN----AGS-AN
tr_Q8VHC1CystatinN_Rattusnorve      -------------RTGERQNLSPDDPRVLKAAQAAVASYN----MDS-NS
tr_Q9D1B11110017E11Rikprotein_      -------------RTGERQNLSPTDPRVQKAAQAAVASYN----MGS-DS
sp_Q15828_CYTM_HUMANCystatinMp      -------------MVGELRDLSPDDPQVQKAAQAAVASYN----MGS-NS
tr_P90698Cystatin_Brugiamalayi      --------------LSRATY-NEDDEEIQEVAEKAMEQVN----DQT-RY
tr_Q9U9A1Cystatin_typecysteine      --------------LGKLTNDNEDDEEIQEVAEKAMIQVN----EKM-KY
sp_P22085_CYTX_ONCVOOnchocysta      -------NQDRPVLLGGWEDRDPKDEEILELLPSILMKVN-----EQSND
tr_Q9NH95Ls_cystatin_Litomosoi      -------------VVGGWQERSPDDNEIQEMLPSILTKVN-----QQSND
tr_Q9TYY2K08B4.6protein_Cystat      ----------------GLS--DVNASEYTGAAWNSVPEIN-----SKNNG
tr_Q966W0Nippocystatinprecurso      ----------------GFTPQDVSDPEYMTRAWKAAKGIND---DASNEG
sp_P08934_KNG_RATKininogenprec      YPGDDLFELLPEDCPGCPRNIPVDSPELKEALGHSIAQLN-----AENNH
sp_P01042_KNG_HUMANKininogenpr      YPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLN-----AENNA
sp_O88969_CST8_RATCystatin_rel      -------------AQRYFGSISISNANVKQCVWFAMKEYN----KGS-ED
sp_O60676_CST8_HUMANCystatin_r      -------------VLRKLKPVNASNANVKQCLWFAMQEYN----KES-ED
tr_Q9DAP11700006C19Rikprotein_      -------------IVRPFEDIPKSYVYVQHALWYAMKEYN----KAS-ND
tr_Q8K5A3Cystatin11_Rattusnorv      -----------------VEEVNALESSVKETLEYVTEEYN-----KKSED
tr_Q7M429Cystatinprecursor_Tac      ---------------GGWIDANVGDTDVKEAARFATEAQS-----SRSNS
tr_Q80Y72Cystatin_like1_Musmus      --------------WGGFKEKAMSKKNINSTLHFFIRSYN-----NASND
tr_Q8JFU5SI_dZ57F23.1_Novelpro      -----------VELLGGWTDANPDREDVQEAAKEAVEQFN-----SKPRA
tr_Q7M224Cystatin_Perseaameric      -----------PLLGGVRDVPDHNSAETEELARFAVQEHN-------KKA
tr_Q84XY6Cystatin_Malusdomesti      ---------------RKEIENVKTNKEVQELGRFSVEEYNRQRGTQKMDG
                                                                           .          

sp_P81061_CYT_COTJACystatin_Eg      KYSSRVVRIISAKQQLVSGIKYIMEVEIGRTTCPKSS-ADLQSCEFHDEP
sp_P01038_CYT_CHICKCystatinpre      KYSSRVVRVISAKRQLVSGIKYILQVEIGRTTCPKSS-GDLQSCEFHDEP
sp_O19093_CYTC_SAISCCystatinCp      MYHSRALQVVRARKQIVAGVNYFLDVEMGRTTCTKNQ-PNLDNCPFHEQP
sp_P21460_CYTC_MOUSECystatinCp      AYHSRAIQVVRARKQLVAGVNYFLDVEMGRTTCTKSQ-TNLTDCPFHDQP
sp_O97862_CYTC_RABITCystatinCp      RYHSRALQVVRARRQIVSGVKYYLDVLIGRTTCTKTQ-TNLANCPFHDQP
sp_P01035_CYTC_BOVINCystatinCp      AYQSRVVRVVRARKQVVSGMNYFLDVELGRTTCTKSQ-ANLDSCPFHNQP
sp_P28325_CYTD_HUMANCystatinDp      EYYSRPLQVMAAYQQIVGGVNYYFNVKFGRTTCTKSQ-PNLDNCPFNDQP
sp_P01036_CYTS_HUMANCystatinSp      EYYRRPLQVLRAREQTFGGVNYFFDVEVGRTICTKSQ-PNLDTCAFHEQP
sp_P19313_CYTS_RATCystatinSpre      LYLSRVVEVKDVQKQVVAGTKFFFDVILGKTICLKTQ-GDLTNCPLNEEA
tr_Q9JM84DD72protein_Similarto      LYLSKPIRLMSASQQVVAGKNYYLKIELGRTTCTKTE-SNLVDCPFNEQP
sp_O89098_CYTF_MOUSECystatinFp      IFLFKESHVSKALVQVVKGLKYMLEVKIGRTTCRKTMHHQLDNCDFQTNP
tr_Q7Z4J8CystatinF_Leukocystat      MFLFKESRITRALVQIVKGLKYMLEVEIGRTTCKKNQHLRLDDCDFQTNH
sp_Q91195_CYT_ONCMYCystatinpre      MFVRQVAKVVNAQKQVVSGMKYIFTVQMGRTPCRKG--GVEKVCSVHKDP
sp_P35481_CYT_CYPCACystatinpre      AFVRKVSKVIKVQQQVAAGMKYIFTVKMEVASCKKG--GVKTMCAVPKNP
sp_P08935_CYT_BITARCystatin_Bi      DYYFKERRVVEAQSQVVSGVKYYLMMELLKTTCKKTVGRPKGYQEIQNCN
tn_AAR24527Cystatin_Bitisgabon      DNYFKARRIVEAQSQVVSGVKYYLKMELAKTTCKKIAGKPKLYQEIQNCN
sp_P81714_CYT_NAJATCystatin_Fr      AHYYKELRVVEAQSQSVAGEKYFLMMELVKTKCAKTAGKPKVYKEIQNCE
tr_Q8VHC1CystatinN_Rattusnorve      LYYFRDTKVIDAKCQLVAGIKYYMTVDIESTECRKTR-VSGDHVDLTTCP
tr_Q9D1B11110017E11Rikprotein_      LYYFRDTKVIDAKYQLVAGIKYYLTLDIESTECRKTR-VSGEHMDLTTCP
sp_Q15828_CYTM_HUMANCystatinMp      IYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTR-VTGDHVDLTTCP
tr_P90698Cystatin_Brugiamalayi      RNLYKLVRVISAQTQVVAGIKYYLTILAAPTTCRKGAVGMNPMKCTIDSS
tr_Q9U9A1Cystatin_typecysteine      DNLYKLVKVINARTQVVAGMKYYLTILTAPTTCRK-NSGMSPANCAIDHS
sp_P22085_CYTX_ONCVOOnchocysta      EYHLMPIKLLKVSSQVVAGVKYKMDVQVARSQCKK---SSNEKVDLTKCK
tr_Q9NH95Ls_cystatin_Litomosoi      AYHLMPIKVLKVSSQVVAGMKYKMEIQVARSDCKK---SSNEKIDLKTCK
tr_Q9TYY2K08B4.6protein_Cystat      QNYMVPIKVVKAQVQVVAGTNTVLEVLVGESTCPRQGSVQASQVTAANCP
tr_Q966W0Nippocystatinprecurso      PYHMIPVKILNAKTQVVAGVNHVFEVLFGESSCKK-GDLSASELTATNCQ
sp_P08934_KNG_RATKininogenprec      TFYFKIDTVKKATSQVVAGTKYVIEFIARETKCSK---ESNAELTADCET
sp_P01042_KNG_HUMANKininogenpr      TFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSK---ESNEELTESCET
sp_O88969_CST8_RATCystatin_rel      KYLFLLDKTLHATLQITDRMEYHIDVQISRSNCRKPL-NNTENCIPQKNP
sp_O60676_CST8_HUMANCystatin_r      KYVFLVVKTLQAQLQVTNLLEYLIDVEIARSDCRKPL-STNEICAIQENS
tr_Q9DAP11700006C19Rikprotein_      LYNFRVVDILKSQEQITDSLEYYLEVNIARTMCKKVA-GDNENCLFQQDP
tr_Q8K5A3Cystatin11_Rattusnorv      LYNFRILRILKIEKQMTNHMEFHITVEMQRTTCLKTE---KNLCNVQEGE
tr_Q7M429Cystatinprecursor_Tac      LYHHKLLKIHKARTQVVSGINYEVFIETGTTTCKKSEVPLEDLKRCAVPE
tr_Q80Y72Cystatin_like1_Musmus      TYLYQVQKLIQGQMQLTTGVEYLVTVKIGRTKCKKNE-TKKASCPLQSSK
tr_Q8JFU5SI_dZ57F23.1_Novelpro      KKYFKLIKITSASTQVTNRINYKIEAIIGKTKCHKSEGVNIETCLMAKKQ
tr_Q7M224Cystatin_Perseaameric      NTRLEFSRVVKAKEQVVAGTMYYITLEVVEAGQKK---------------
tr_Q84XY6Cystatin_Malusdomesti      GGELQFLEVVEAQSQVVSGIKYYLKVSAVRNGVHR---------------
                                                  *        .          :               

sp_P81061_CYT_COTJACystatin_Eg      E-----MAKYTTCNFVVYSIPWLNQIKLLKSSCQ-------------
sp_P01038_CYT_CHICKCystatinpre      E-----MAKYTTCTFVVYSIPWLNQIKLLESKCQ-------------
sp_O19093_CYTC_SAISCCystatinCp      H-----LKRKAFCSFQIYSVPWQGIMTLSKSTCQDA-----------
sp_P21460_CYTC_MOUSECystatinCp      H-----LMRKALCSFQIYSVPWKGTHSLTKFSCKNA-----------
sp_O97862_CYTC_RABITCystatinCp      D-----LQRKMLCSFEIYSVPWLNKISLLKSDCQNA-----------
sp_P01035_CYTC_BOVINCystatinCp      H-----LKREKLCSFQVYVVPWMNTINLVKFSCQD------------
sp_P28325_CYTD_HUMANCystatinDp      K-----LKEEEFCSFQINEVPWEDKISILNYKCRKV-----------
sp_P01036_CYTS_HUMANCystatinSp      E-----LQKKQLCSFEIYEVPWEDRMSLVNSRCQEA-----------
sp_P19313_CYTS_RATCystatinSpre      D-----QQEHEFCSFVVHDIPWENYIVLLSSSCHSI-----------
tr_Q9JM84DD72protein_Similarto      D-----QQKRVICNFQINVAPWLNKMSMTNFNCYNF-----------
sp_O89098_CYTF_MOUSECystatinFp      A-----LKRTLYCYSEVWVIPWLHSFEVPVLLCQ-------------
tr_Q7Z4J8CystatinF_Leukocystat      T-----LKQTLSCYSEVWVVPWLQHFEVPVLRCH-------------
sp_Q91195_CYT_ONCMYCystatinpre      Q-----MAVPYKCTFEVWSRPWMSDIQMVKNQCES------------
sp_P35481_CYT_CYPCACystatinpre      S-----IEQVIQCKITVWSQPWLNSLKVTENTCM-------------
sp_P08935_CYT_BITARCystatin_Bi      LPPE-NQQEEITCRFEVWSRPWLPSTSLTK-----------------
tn_AAR24527Cystatin_Bitisgabon      LPPE-NQQEEITCHFEVWSRPWLQKTVLTKDEL--------------
sp_P81714_CYT_NAJATCystatin_Fr      LPPI-KQQEEKLCGFQVW-----------------------------
tr_Q8VHC1CystatinN_Rattusnorve      LAAG-VQQEKLRCNFELLEVPWKNTTQLLKHDCVQV-----------
tr_Q9D1B11110017E11Rikprotein_      LAAG-GQQEKLRCNFELLEVPWKNTTQLLKHDCVQV-----------
sp_Q15828_CYTM_HUMANCystatinMp      LAAG-AQQEKLRCDFEVLVVPWQNSSQLLKHNCVQM-----------
tr_P90698Cystatin_Brugiamalayi      K-------PTKQFKIEVWSAPWQNTFKVTLT----------------
tr_Q9U9A1Cystatin_typecysteine      K-------PKKKVILEVWSAPWQNIFKVTMA----------------
sp_P22085_CYTX_ONCVOOnchocysta      KL---EGHPEKVMTLEVWEKPWENFMRVEILGTKEV-----------
tr_Q9NH95Ls_cystatin_Litomosoi      KL---EGHPDQIITLEVWEKAWEDFLQVNILETKLLS----------
tr_Q9TYY2K08B4.6protein_Cystat      LK---SGGKRELYKVSIWEKPWENFKQTKAEKIRGVKPDEKI-----
tr_Q966W0Nippocystatinprecurso      LK---EGGRKVIYEVHLWEKPWENFEQFNVKKVRTLAPGEQV-----
sp_P08934_KNG_RATKininogenprec      KRLGQSLNCNANVYMRPWENKVVPTVKCKVLDMTSVIRRPPGFSPFR
sp_P01042_KNG_HUMANKininogenpr      KKLGQSLDCNAEVYVVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFR
sp_O88969_CST8_RATCystatin_rel      K-----LEKKLSCSFLVGALPWNGEFDLLSKECKDV-----------
sp_O60676_CST8_HUMANCystatin_r      K-----LKRKLSCSFLVGALPWNGEFTVMEKKCEDA-----------
tr_Q9DAP11700006C19Rikprotein_      K-----MKKMVFCIFIVSSKPWKFELKMLKKQCKDI-----------
tr_Q8K5A3Cystatin11_Rattusnorv      ------LHKQIQCYFSVYVIPWLEVFKMLKKNCTNSS----------
tr_Q7M429Cystatinprecursor_Tac      N------GVKHLCQAIVWVQAWIPRTKVTKLECQNKG----------
tr_Q80Y72Cystatin_like1_Musmus      LK------KSLICKSLIYSVPWMNYYQLWNNSCQES-----------
tr_Q8JFU5SI_dZ57F23.1_Novelpro      LT----------CKFEVTMDPMNDDHEVHKMICKRSA----------
tr_Q7M224Cystatin_Perseaameric      -----------IYEAKVWVKLWENFKELQEFKPVGDSSSTSSDA---
tr_Q84XY6Cystatin_Malusdomesti      -----------LFDSEVVVKPWLRSKQLLNFAPHGPK----------