CLUSTAL X (1.81) multiple sequence alignment


tn_CAD66666ComplementC4_Oncorh      ---------MGSPVCLMVLFILAAESVHGQDRFFISAPNVFHVGVKERVY
tr_Q9I932ComplementC4B_Cyprinu      ------MEVHMRPLLCLLLCMCSAVQGENRKRFLITAPSVFHVGVKEPVW
sp_P01028_CO4_HUMANComplementC      ----------MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVG
sp_P01029_CO4_MOUSEComplementC      ----------MRLLWGLAWVFSFCASSLQKPRLLLFSPSVVNLGTPLSVG
tr_Q9I933ComplementC4A_Cyprinu      -----------MICPLCFVVFVFLTVDAHRPTCLIVAPNVIHVGVEETVS
tn_BAC82347ComplementC4_Triaki      ------------MFLLLLCLFAAASVTEQTLSFLIIGPNIIHTGVEESVS
tr_Q9YIA5ComplementC3_Q2_Cypri      --------MEVKLLFLTVVLLSSPLLTLCDPLYVLSAPNLLRVGSSENMF
tr_Q9YIA9ComplementC3_H1_Cypri      --------MEVKLLFLTVVLLSSPLLTLCNPLYVLSAPNLLRVGSSENVF
tn_AAQ74974ComplementC3_Ctenop      --------MGVKLLWLTVVLLSSPLLTLCDPLYVLSAPNLLRVGSSENVF
tr_Q9YIA7ComplementC3_S_Cyprin      --------MGVKLLFLTVVLLSSPLLTLCDPLFVLSAPNLLRVGSSENVF
tr_Q9YIB0ComplementC3_H1_Cypri      --------MEVKLLFLTVVLLSSPLLTLCNPLYVLSAPNLLRVGSSENVF
sp_P98093_CO3_ONCMYComplementC      -----------------------------AALQVLSAPNLLRVGSNENIF
tr_Q98TS6ComplementcomponentC3      ------MSRTLLWLVASVALASLTSLADGASLKVMSAPNLLRVGTAENIF
tr_Q9PTY1ComplementcomponentC3      ------MGRTQLWLLASLAFASIASLVDGAPLKVMSAPNLLRVGTTENIF
tr_Q9IBH1OrlaC3_1protein_Oryzi      ------MRRALQLLLASLALVSLMSLIDAGPLNLMSAPNLLRVGTPENIF
tr_Q9IBH0OrlaC3_2protein_Oryzi      ------MRRALQLLLASLALVSLMSFIDAGPLNLMSAPNLLRVGTPENIF
sp_Q01833_CO3_NAJNAComplementC      -------MEGMALYLVAALLIGFPGSSH-GALYTLITPAVLRTDTEEQIL
tr_Q91132Cobravenomfactorprecu      -------MERMALYLVAALLIGFPGSSH-GALYTLITPAVLRTDTEEQIL
tr_Q91588ComplementcomponentC3      --------------------------------------------------
tr_Q90633ComplementC3precursor      -------MGLLLLPLLLGVLLLHAVPTP-AQMVTMVTPAVLRLDTDEKVV
sp_P01024_CO3_HUMANComplementC      -----MGPTSGPSLLLLLLTHLP--LALGSPMYSIITPNILRLESEETMV
tr_Q80XP1Complementcomponent3_      -----MGPASGSQLLVLLLLLASSPLALGIPMYSIITPNVLRLESEETIV
sp_P01026_CO3_RATComplementC3p      -----MGPTSGSQLLVLLLLLASSLLALGSPMYSIITPNVLRLESEETFI
sp_P01027_CO3_MOUSEComplementC      -----MGPASGSQLLVLLLLLASSPLALGIPMYSIITPNVLRLESEETIV
sp_P12387_CO3_CAVPOComplementC      -----MGPAAGP--SLLLLLLASVSLALGDPMYSIITPNILRLENEETVV
tr_Q9GKP1ComplementcomponentC3      -----MGSTSGP--RLLLLLLTSLPLALGDPIYTIITPNVLRLESEEMVV
sp_Q00685_CO3_LAMJAComplementC      ----------------VLLLMSVGTSVTQDPMVLLSVPSVILIGSDVNVL
sp_P98094_CO3_EPTBUComplementC      ----------------------------------VLVIAPAATSSYDDLA
sp_P01031_CO5_HUMANComplementC      ----------MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIV
tr_Q8AYN9ComplementcomponentC5      ----------MARLFLLCILHLFVCITVQESVYLITAPKLLRLDASEKVV
tr_Q969A4ComplementcomponentC3      ----------MIRSLVCVCLLFAAVLGQQGPAYFISVPNLLKVGTEETVS
tr_Q03626Alpha_1_inhibitorIIIp      --MKKNREAQLCLFSALLAFLPFASLLNGNSKYMVLVPSQLYTETPEKIC
tr_Q9PVU4Alpha_2_macroglobulin      -------------------------GQTSGPSFTVTFPAVIESGSEAKLC
tr_O44344ComplementcomponentC3      ----MGSIILIFVLAISASLVPGGVTQDPPATFFVISPNVFRAGVEEKVV
tr_Q8I7P1ComplementcomponentC3      ---------MKMLRALIGFALLLCLNQCYAAKYFIAAPNLLRVGVEETVS
tr_O97019AsC3protein_Halocynth      --------MISFHIYICILFFLTRAKLTVSCSYSLVLPKALRVDTENYAY
tr_Q8WPD8ComplementcomponentC3      ------------MVWFSFSLLVTLLAVATAFDHTVVVPKALRVDADEKII
tr_Q8TDJ3CD109_Homosapiens_Hum      -----MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIG
tr_Q8IZJ3Alpha_2macroglobulinf      MSGALLWPLLPLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAGVEEVIS
tr_Q7Q7S6AgCP4019_Anophelesgam      -----------MWQFIRSRILTVIIFIAAAHGLLVMGPKCIRDNQNYTLT
                                                                                      

tn_CAD66666ComplementC4_Oncorh      VQLGKALLNKRVT----LYLEHEETTHLMSQKSSTVCTEEGQIQTVELEV
tr_Q9I932ComplementC4B_Cyprinu      IQVGGALLGKPVS----CQLETEMRVPMSTRETKTITKK-GQFEAVNLEI
sp_P01028_CO4_HUMANComplementC      VQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSERDFALLSLQVP
sp_P01029_CO4_MOUSEComplementC      VQLLDAPPGQEVKGSVFLRNPKGG--SCSPKKDFKLSSGDDFVLLSLEVP
tr_Q9I933ComplementC4A_Cyprinu      VQLHGATKETSMQ---LYFQEQISRIIVSEKKSIILNKDNNYQAVVKLKV
tn_BAC82347ComplementC4_Triaki      IQLHDAEGTVNFQ---VYCWDLIKRKKCSETALFTLNPGNNYQENKTITV
tr_Q9YIA5ComplementC3_Q2_Cypri      VEAQDYSREDLNVKIIVKNHPKKDMDILSKSVTLTAANCFQILT------
tr_Q9YIA9ComplementC3_H1_Cypri      VEAQDYSGAAFDVKIIVKNHPKKDKEILSQSVSLTAANNFQILKDIKIPD
tn_AAQ74974ComplementC3_Ctenop      VEAQDYTGGAFEVKIIVQNHPKKDKEILSKTVTLTADNNYQILTDITIAD
tr_Q9YIA7ComplementC3_S_Cyprin      VEAQDYSGAAIEVKIIVKNHPKKDREILSQSVRLTADNNFQIIKDIKIPD
tr_Q9YIB0ComplementC3_H1_Cypri      VEAQDYSGAAFDVKIIVKNHPKKDKEILSQSVSLTAANNFQILKDIKIPD
sp_P98093_CO3_ONCMYComplementC      VESQDHVGGPLNVKIMVKNHPTQSKELASKSVVLDQANNFQAMTQLVIQ-
tr_Q98TS6ComplementcomponentC3      VECQDCTGAAINVQINVMNHPTKSQKLATAAVTLNADNKFQQLGEITIP-
tr_Q9PTY1ComplementcomponentC3      VECQDCTGGDIKVDINVMNHPTKVNRLATTSVTLTSGQNFQALGQIRIP-
tr_Q9IBH1OrlaC3_1protein_Oryzi      VECQDCSGANQPVTISVKNHPTKAKTLATTQVTLTNDNNFQGFGQITIPP
tr_Q9IBH0OrlaC3_2protein_Oryzi      VECQDCSGVNQLVTIFVKNHPTKTKTLTTTQVTLTNDNNFQGFAQITIP-
sp_Q01833_CO3_NAJNAComplementC      VEAHGDST-PKSLDIFVHDFPRKQKTLFQSRVDMNQAGSMFVTPTIKVPA
tr_Q91132Cobravenomfactorprecu      VEAHGDST-PKQLDIFVHDFPRKQKTLFQTRVDMNPAGGMLVTPTIEIPA
tr_Q91588ComplementcomponentC3      ---------------------------------AAGNNGFLGTATVKIPS
tr_Q90633ComplementC3precursor      LEAPGLSA-PTEANILVQDFPQKRKVLFQVRKQLNPAEGMMAIATVKVP-
sp_P01024_CO3_HUMANComplementC      LEAHDAQG-DVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGNVTFTIPA
tr_Q80XP1Complementcomponent3_      LEAHDAQG-DIPVTVTVQDFLKR-QVLTSEKTVLTGASGHLRSVSIKIPA
sp_P01026_CO3_RATComplementC3p      LEAHDAQG-DVPVTVTVQDFLKK-QVLTSEKTVLTGATGHLNRVFIKIPA
sp_P01027_CO3_MOUSEComplementC      LEAHDAQG-DIPVTVTVQDFLKR-QVLTSEKTVLTGASGHLRSVSIKIPA
sp_P12387_CO3_CAVPOComplementC      LEAHEVQG-DIPVTVTVHDFPAKKNVLSSEKTVLTSATGYLGTVTIKIPA
tr_Q9GKP1ComplementcomponentC3      LEAHEGQG-DIRVSVTVHDFPAKRQVLSSETTTLNNANNYLSTVNIKIPA
sp_Q00685_CO3_LAMJAComplementC      VDHAASTEDVSVVVRAEEFLTKKQLATQTITLTQLDPAIATLKLGFDIEN
sp_P98094_CO3_EPTBUComplementC      VAILMVDQKKITEVHVLLVNPHTGATLDEKKVKLQWDNKFIAFTKLQVTP
sp_P01031_CO5_HUMANComplementC      IQVYGYTEAFDATISIK-SYPDKKFSYSSGHVHLSSENKFQNSAILTIQP
tr_Q8AYN9ComplementcomponentC5      VQLFGYDKEMTVDLHLKNTLAPSYKQYASQSLKLNAANNYQASATLRIMA
tr_Q969A4ComplementcomponentC3      VNVFNVAN-PVRVKVYLQDYPDRKTTFSEAEVDVNQDEPSLVTVRVNPDN
tr_Q03626Alpha_1_inhibitorIIIp      LHLYHLNETVTVTASLISQRGTRKLFDELVVDKDLFHCLSFTIPRLPSSE
tr_Q9PVU4Alpha_2_macroglobulin      ASLLKPNESLVMNIYLVHG-DQSTLLLQEKAEEEFHRCFNFKAP-LVEEE
tr_O44344ComplementcomponentC3      VTLIRSPPNVQNIEVKVSLMRPGSTVTFSEDTRLVSPGSSQSFSVVIQAG
tr_Q8I7P1ComplementcomponentC3      IAVFDVNVDVNVQLALQDFPNRRKTFSQVSGNVRAQQPGILKIKVNAKDL
tr_O97019AsC3protein_Halocynth      IDFHNCPPIAKISTSLHSLPGIENTHSSDEKVDHPTIDPIKLTYVPKSKM
tr_Q8WPD8ComplementcomponentC3      VNLHGYNRATITGYLQDLPGLQTFFSRTGQRVLTPAQCQNPIEMTFRVTR
tr_Q8TDJ3CD109_Homosapiens_Hum      VELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPL
tr_Q8IZJ3Alpha_2macroglobulinf      VTIFNSPR----------EVTVQAQLVAQGEPVVQSQGAILDKGTIKLKV
tr_Q7Q7S6AgCP4019_Anophelesgam      ISNFYSNPSKLDLMVKLEGKNDNGLSVLNVTKMIDVPCKSIRMINFSILD
                                                                                      

tn_CAD66666ComplementC4_Oncorh      ERDK----LPTFGDIPYLLLVAEMDGVTG-----------RKMVRVLVSQ
tr_Q9I932ComplementC4B_Cyprinu      FESKSSELKSINGEPPYLNLACEVDGQK-------------RQTRVLVSK
sp_P01028_CO4_HUMANComplementC      LKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLS----RTTNIQGINLLFSS
sp_P01029_CO4_MOUSEComplementC      LEDVRSCGLFDLRRAPHIQLVAQSPWLRNTAF----KATETQGVNLLFSS
tr_Q9I933ComplementC4A_Cyprinu      DR----SLYGSKKDEKYVQLAATSNDVFWN------TVGSARKASIYLST
tn_BAC82347ComplementC4_Triaki      SQHKVKELSLWRRRQKYVYLVAESRQILQ----------QRRMVPIKLSN
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      D---QNYFSDDPLEKQYVYLQAHFPSVILEK-------------VVLLSF
tn_AAQ74974ComplementC3_Ctenop      D---KNFFSDDPLEKQYVYLQAQFPSKTLEK-------------VVMVSF
tr_Q9YIA7ComplementC3_S_Cyprin      D---QNYFSDNPLEKQYVYLQAQFPSVTLEK-------------EVMVSF
tr_Q9YIB0ComplementC3_H1_Cypri      D---QNYFSDDPLEKQYVYLQAHFPSVILEK-------------VVLLSF
sp_P98093_CO3_ONCMYComplementC      ----RGPLVDDPKQKQYVVLQAQFPDRLLEK-------------VVLVSF
tr_Q98TS6ComplementcomponentC3      ----AGDFSKDATMKQYVYLQAEFPDRVLEK-------------VVLVSF
tr_Q9PTY1ComplementcomponentC3      ----AGGFSKDPRLKQYVYLQAQFPDRLLEK-------------VVLVSF
tr_Q9IBH1OrlaC3_1protein_Oryzi      G---D--FSKDPSVKQYVYLEAAFPGRTLEK-------------VVMVSF
tr_Q9IBH0OrlaC3_2protein_Oryzi      ----PGDFNKDPSVKQFVYLEAVFPDRTLEK-------------FVMVSF
sp_Q01833_CO3_NAJNAComplementC      -----KELNKDSKQNQYVVVKVTGPQVALEK-------------VVLLSY
tr_Q91132Cobravenomfactorprecu      -----KEVSTDSRQNQYVVVQVTGPQVRLEK-------------VVLLSY
tr_Q91588ComplementcomponentC3      -----GDLSKDTKSKQYVYVSVKSNVCALEK-------------VVLLSY
tr_Q90633ComplementC3precursor      ----VKLLP-PVVGKHFVSVVARVGQVTLEK-------------VLLVSL
sp_P01024_CO3_HUMANComplementC      ----NREFKSEKGRNKFVTVQATFGTQVVEK-------------VVLVSL
tr_Q80XP1Complementcomponent3_      ----SKEFNSDKEGHKYVTVVANFGETVVEK-------------AVMVSF
sp_P01026_CO3_RATComplementC3p      ----SKEFNADKG-HKYVTVVANFGATVVEK-------------AVLVSF
sp_P01027_CO3_MOUSEComplementC      ----SKEFNSDKEGHKYVTVVANFGETVVEK-------------AVMVSF
sp_P12387_CO3_CAVPOComplementC      ----SKEFK-SDKGRKLVVVQAAFGGTQLEK-------------VVLVSL
tr_Q9GKP1ComplementcomponentC3      ----SKEFKSEKG-HKFVTVQALFGNVQVEK-------------VVLVSL
sp_Q00685_CO3_LAMJAComplementC      P-----DKTNSASTKHHVRLVAKVESKSFNKEITA---------HALLSY
sp_P98094_CO3_EPTBUComplementC      -------KEVEKWKEDFVRLMVKWDGGQHMEI------------DIPLTS
sp_P01031_CO5_HUMANComplementC      -----KQLPGGQNPVSYVYLEVVSKHFSKSK-------------RMPITY
tr_Q8AYN9ComplementcomponentC5      -----TDFPKEDN---YVYLQAVSSAFTAHE-------------KIPVTA
tr_Q969A4ComplementcomponentC3      LP-----ESRATKRYVYVVAKSDDPQLTFQK-----------EAQVLLSY
tr_Q03626Alpha_1_inhibitorIIIp      -----------EEESLDINIEGAKHKFSERR-------------VVLVKN
tr_Q9PVU4Alpha_2_macroglobulin      -----------SVQRMKVELQGESFKITEER-------------KVMFRR
tr_O44344ComplementcomponentC3      ------DLMRNEGAFQHMVLKAESLNPIYPFEEQTD---------ILVTL
tr_Q8I7P1ComplementcomponentC3      HD-------QQSLDKQYVYLIASSSTAGFQFR---------DEIKILVSY
tr_O97019AsC3protein_Halocynth      MENRKKTTTPYKKALVVINYCFGVNCQFQN---------PAEKFTIPLNS
tr_Q8WPD8ComplementcomponentC3      DPQGADGIASFGLTQKVRLTIQVTNSNSDFTEN----------IDVLVSK
tr_Q8TDJ3CD109_Homosapiens_Hum      N-------SADEIYELRVTGRTQDEILFSNS------------TRLSFET
tr_Q8IZJ3Alpha_2macroglobulinf      PTGLRGQALLKVWGRGWQAEEGPLFHNQTS---------------VTVDG
tr_Q7Q7S6AgCP4019_Anophelesgam      SLSSGNYKITIDGLQGFNFHEEAELVYLSK--------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      HRGYIFIQTDQPIYNPTQQVRYRIFTLNHSMKPHDD--------------
tr_Q9I932ComplementC4B_Cyprinu      HSGYIFIQTNQPIYNPKQKVSFRIFTFDHSMRPKSE--------------
sp_P01028_CO4_HUMANComplementC      RRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTD--------------
sp_P01029_CO4_MOUSEComplementC      RRGHIFVQTDQPIYNPGQRVRYRVFALDQKMRPSTD--------------
tr_Q9I933ComplementC4A_Cyprinu      KRGYIFIQTDKPIYNPGENVKYRIFTLDNFMLPIKD--------------
tn_BAC82347ComplementC4_Triaki      KMGYIFIQTDQPIYTPNQIVMFRIFTLDHYMRPSNN--------------
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      QSGYIFVQTDKPIYTPASTVQYRIFSLTPNLEPLS-------------QS
tn_AAQ74974ComplementC3_Ctenop      QSGYIFVQTDKPIYTPASTVQYRIFSLTPNLKPLS-------------QS
tr_Q9YIA7ComplementC3_S_Cyprin      QSGYIFVQTDKPIYTPASTVQYRIFSLTPNLEPLS-------------QS
tr_Q9YIB0ComplementC3_H1_Cypri      QSGYIFVQTDKPIYTPASTVQYRIFSLTPNLEPLS-------------QS
sp_P98093_CO3_ONCMYComplementC      QSGYIFIQTDKTIYTPASTVHYRVFSMTPGLEPLTREIFEDQEVAKNKEI
tr_Q98TS6ComplementcomponentC3      QSGYIFIQTDKTLYTPNSKVHYRMFAVTPRMEPVER------DAATQTDT
tr_Q9PTY1ComplementcomponentC3      QSGFIFIQTDKTIYTPNSKVLYRMFAVTPTMEPVER------DEQIQNEA
tr_Q9IBH1OrlaC3_1protein_Oryzi      QSGYIFIQTDKTLYTPNSKVYYRMFGVTPRMEPLER------LNDAQTDT
tr_Q9IBH0OrlaC3_2protein_Oryzi      QSGYIFIQTDKTLYTPNSKVYYRMFGVTPRMEPVER------LNDAKTDT
sp_Q01833_CO3_NAJNAComplementC      QSGFVFIQTDKGIYTPGSPVRYRVFSVDHNMHRMDK--------------
tr_Q91132Cobravenomfactorprecu      QSSFLFIQTDKGIYTPGSPVLYRVFSMDHNTSKMNK--------------
tr_Q91588ComplementcomponentC3      HSGYIFLQTDKTIYTPGSTVLYRIYSMNYKMQPISK--------------
tr_Q90633ComplementC3precursor      QSGHIFLQTDKPIYTPGSTVLSRLFALSHFMQPLLK--------------
sp_P01024_CO3_HUMANComplementC      QSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGR--------------
tr_Q80XP1Complementcomponent3_      QSGYLFIQTDKTIYTPGSTVLYRIFTVDNNLLPVGK--------------
sp_P01026_CO3_RATComplementC3p      QSGYLFIQTDKTIYTPGSTVFYRIFTVDNNLLPVGK--------------
sp_P01027_CO3_MOUSEComplementC      QSGYLFIQTDKTIYTPGSTVLYRIFTVDNNLLPVGK--------------
sp_P12387_CO3_CAVPOComplementC      QSGYLFIQTDKTIYTPGSTVLYRIFTVDSDLLPVGR--------------
tr_Q9GKP1ComplementcomponentC3      QSGYLFIQTDKTIYTPGSTVLYRIFTVDHKLLPVGQ--------------
sp_Q00685_CO3_LAMJAComplementC      RSGHVVVQTDKPIYTPDEKVKYRMFPMNREDVHRIP-----------VRQ
sp_P98094_CO3_EPTBUComplementC      RRGLVFAQTDQPIYTPNNDVNIRLFPVTRQLNPILS--------------
sp_P01031_CO5_HUMANComplementC      DNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKR--------------
tr_Q8AYN9ComplementcomponentC5      VNGFLFIQTDKPLYTPEQEVQVRVYSLNEELRKSRR--------------
tr_Q969A4ComplementcomponentC3      QQGYVFVQTDKPIYTPNQKVKMRIMPLDQDMTPASQP-------------
tr_Q03626Alpha_1_inhibitorIIIp      KESVVFVQTDKPVYKPGQSVKFRVVSMDKNLHPLNE-------------L
tr_Q9PVU4Alpha_2_macroglobulin      YHPLTFIQTDKPIYIPGQTVNFRVVTMDKNFSPLDQ-------------Q
tr_O44344ComplementcomponentC3      QSGYVFVQTDKPIYTPNQDVMIKVMSLDQDMLPSDR--------------
tr_Q8I7P1ComplementcomponentC3      RSAMVFIQTDKPIYNPGQTVNLRVVPLSLDLKASVDN-------------
tr_O97019AsC3protein_Halocynth      THGYVFMTTSRPAYRPGENVHISVAGLAQSFTAARG---------DLPLP
tr_Q8WPD8ComplementcomponentC3      QSGYIYVITDRPIYKPNDTVKISAFLLNQNMGHQTG-------------V
tr_Q8TDJ3CD109_Homosapiens_Hum      KRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTS-------------
tr_Q8IZJ3Alpha_2macroglobulinf      RGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEK-------------
tr_Q7Q7S6AgCP4019_Anophelesgam      -SISGVIQIDKPVIKPGDTVIFRVIVLDTALKPPVR------------VK
                                                                                      

tn_CAD66666ComplementC4_Oncorh      VFQISIFNAAGNRIMKTLKRATDGIFTN-----IPFNIPDVSEMGVWRIV
tr_Q9I932ComplementC4B_Cyprinu      IVYVYIYNAEGNKIKKSTYKVLGGVLS------KDYHIPDISKPGVWKIT
sp_P01028_CO4_HUMANComplementC      TITVMVENSHGLRVRKKEVYMPSSIFQ------DDFVIPDISEPGTWKIS
sp_P01029_CO4_MOUSEComplementC      FLTITVENSHGLRVLKKEIFTSTSIFQ------DAFTIPDISEPGTWKIS
tr_Q9I933ComplementC4A_Cyprinu      EIHVQIINCKGFIVYN--HILISDQILE-----KTITIPEVEQEGKWKII
tn_BAC82347ComplementC4_Triaki      QLRVSIYNSRNMQIMG--AVWMSEKIKL-----LRTKIPDNEESGIWRIE
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      GITVEIMNPQGITVSSEKIFPVK----G--MKSGKYAIPEMASPGIWKVV
tn_AAQ74974ComplementC3_Ctenop      GVTVEIMNPQGITVSSEKIYPVK----G--IKSGKYAIPEVSSLGIWKVV
tr_Q9YIA7ComplementC3_S_Cyprin      GITVEIMNPQGITVSSEKIFPVK----G--MKSGKYPIPEIASPGIWKVV
tr_Q9YIB0ComplementC3_H1_Cypri      GITVEIMNPQGITVSSEKIFPVK----G--MKSGKYAIPEMASPGIWKVV
sp_P98093_CO3_ONCMYComplementC      AVSVEIMTPENITIFREIVNPDK----G--VKSGQFKLPDIVSFGTWHVV
tr_Q98TS6ComplementcomponentC3      SISIEFVTPKGIILPLDSVALKS----G--IHSGDFQLAEIVSPGLWKVV
tr_Q9PTY1ComplementcomponentC3      SIAIEFVTPEDIVLPLDPVSLKS----G--IHSGEYKLAEIVSPGLWKVV
tr_Q9IBH1OrlaC3_1protein_Oryzi      SISIEIVTPEGIILPLDPVSLKS----G--LHSGDYQLNEIVSPGLWKIV
tr_Q9IBH0OrlaC3_2protein_Oryzi      SISIEIVTPEGIILPLDPVSLKS----G--LHSGDYRLTEIVSPGLWKIV
sp_Q01833_CO3_NAJNAComplementC      TVIVEFQTPEGIVVSSKPVNPSGS--------IRPYNLPELVSFGTWKAV
tr_Q91132Cobravenomfactorprecu      TVIVEFQTPEGILVSSNSVDLN---------FFWPYNLPDLVSLGTWRIV
tr_Q91588ComplementcomponentC3      TLIIEFLTPDGIIVNTHTILQDSKS--G--IISQSHKLPELLSLGVWTIS
tr_Q90633ComplementC3precursor      TVIVEVKTPDNVIIKQVPVSSPMRN--G--IFSINHNLPEVVSLGTWTIT
sp_P01024_CO3_HUMANComplementC      TVMVNIENPEGIPVKQDSLSSQNQL--G--VLPLSWDIPELVNMGQWKIR
tr_Q80XP1Complementcomponent3_      TVVILIETPDGIPVKRDILSSNNQH--G--ILPLSWNIPELVNMGQWKIR
sp_P01026_CO3_RATComplementC3p      TVVIVIETPDGVPIKRDILSSHNQY--G--ILPLSWNIPELVNMGQWKIR
sp_P01027_CO3_MOUSEComplementC      TVVILIETPDGIPVKRDILSSNNQH--G--ILPLSWNIPELVNMGQWKIR
sp_P12387_CO3_CAVPOComplementC      TIIVTIETPDGIPIKRDTLSSNNQH--G--ILPLSWNIPELVNMGQWKIQ
tr_Q9GKP1ComplementcomponentC3      TIVVTIETPEGIDIKRDSLSSHNQF--G--ILALSWNIPELVNMGQWKIR
sp_Q00685_CO3_LAMJAComplementC      SMTVDIVNADGVIVERQIKTIKATD-EG-IVDGTSFTIPAISKHGTWKIF
sp_P98094_CO3_EPTBUComplementC      SLVVDIMNPDGVVVDRIEKNAFEVE-KV--MELRPFHVPAITSLGDWKIV
sp_P01031_CO5_HUMANComplementC      ETVLTFIDPEGSEVDMVEEIDHIGI----ISFP-DFKIPSNPRYGMWTIK
tr_Q8AYN9ComplementcomponentC5      TVTLTFVDPTGIKVEMIDMTDINGA----KPLLPPFKIPLKPIYGIWKIL
tr_Q969A4ComplementcomponentC3      -VKLEILNPQGIIVERKTFPGSATG-----FIAETFDFPAFPLFGNWTAI
tr_Q03626Alpha_1_inhibitorIIIp      FPLAYIEDPKMNRIMQWQDIKTENG-----LKQLSFSLSAEPIQGPYKIV
tr_Q9PVU4Alpha_2_macroglobulin      YSSVVLEDSNRNRIGQWTNVSSTRW-----ILQRSYELNPEGRQGMYKLK
tr_O44344ComplementcomponentC3      ELHVEIMDPSGTSVKRLRETHADVPASIG---RLQVHNHPASVNGPFRLS
tr_Q8I7P1ComplementcomponentC3      -VTIEVMNPQGIRVERWSNLNTKAG-----FFSRRLDLSENVLLGLWTIS
tr_O97019AsC3protein_Halocynth      DVTIKIKTPISLGRMSVQDTLKRMDNEPTGMLRHTYEIPEDPMTGVWWAE
tr_Q8WPD8ComplementcomponentC3      DAEITIQTPDGIGLVRESFVDLQSN-----RLNHEFAINENPIYGTWSIE
tr_Q8TDJ3CD109_Homosapiens_Hum      -LNILIKDPKSNLIQQWLSQQSDLG-----VISKTFQLSSHPILGDWSIQ
tr_Q8IZJ3Alpha_2macroglobulinf      -LEAYILDPRGSRMIEWRHLKPFCCG----ITNMSFPLSDQPVLGEWFIF
tr_Q7Q7S6AgCP4019_Anophelesgam      FVNVIIRDPNDNVIRRWPAAELYAG-----VFESNLQIAITSLLGVWNIS
                                                                                      

tn_CAD66666ComplementC4_Oncorh      AHYQGD-EKSAVTREFQVKKFVLPSFEVTVIPKQSYFLLN---TEQSTFT
tr_Q9I932ComplementC4B_Cyprinu      AHYKGD-EENAAVREFKVQKFVLPSFEVSIHSEKTFLLVN---AETYTFT
sp_P01028_CO4_HUMANComplementC      ARFSDG-LESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLD
sp_P01029_CO4_MOUSEComplementC      ARFSDG-LESNRSTHFEVKKYVLPNFEVKITPWKPYILMVPSNSDEIQLD
tr_Q9I933ComplementC4A_Cyprinu      ASYHKY-PESTTSLEFEVKEYVLPTFEVTIEAPQPYHILK---SQSFPFN
tn_BAC82347ComplementC4_Triaki      AAFLDS-PMSKVSAQFEVKEFVLPRFDVKVQADELFYLVT---KDEFKFK
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      TLFSNT-PQKTFTADFEVKEYVLPTFEVKLKPSKSFFYV---HDESLTVD
tn_AAQ74974ComplementC3_Ctenop      TRFANT-PQKQFTADFEVKEYVLPTFEVKLKPSRSFYYV---DDQSLTVG
tr_Q9YIA7ComplementC3_S_Cyprin      TLFSNT-PQKKFTADFEVKEYVLPTFEVKLKPSKSFFYV---GDPSLTVD
tr_Q9YIB0ComplementC3_H1_Cypri      TLFSNT-PQKTFTADFEVKEYVLPTFEVKLKPSKSFFYV---HDESLTVD
sp_P98093_CO3_ONCMYComplementC      TRFQST-PQKTFSSEFEVKEYVLPSFEVSLTPAKAFFYV---DDNDLTVD
tr_Q98TS6ComplementcomponentC3      TKFNSN-PQQSYSAEFEVKEYVLPSFEVKLTPATSFFYV---DSDELTVN
tr_Q9PTY1ComplementcomponentC3      AKFHSN-PQESFSAEFEVKEYVLPSFEVKLTSTSPFFYV---ESEDLTIN
tr_Q9IBH1OrlaC3_1protein_Oryzi      AKFQSN-PQESFSANFEVKEYVLPSFEVKLSSLRPFFYV---DSETLEID
tr_Q9IBH0OrlaC3_2protein_Oryzi      AKFQSN-PQESFSANFEVKEYVLPSFEVKLSSLRSFFYI---DSETLEID
sp_Q01833_CO3_NAJNAComplementC      AKYEHS-PEESYTAYFDVREYVLPSFEVRLQPSDKFLYID--GNKNFHVS
tr_Q91132Cobravenomfactorprecu      AKYEHS-PEN-YTAYFDVRKYVLPSFEVRLQPSEKFFYID--GNENFHVS
tr_Q91588ComplementcomponentC3      AKYEDT-PQQNYTINFEVKEYVLPSIEIILKPDTNYFYSD--AES-FGVD
tr_Q90633ComplementC3precursor      AKFEDS-QDQVFSTQFEVKEYVLPSFEVTLDPQEKFLYID--PAEDFRVT
sp_P01024_CO3_HUMANComplementC      AYYENS-PQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIY--NEKGLEVT
tr_Q80XP1Complementcomponent3_      AFYEHA-PKQIFSAEFEVKEYVLPSFEVRVEPTETFYYID--DPNGLEVS
sp_P01026_CO3_RATComplementC3p      AFYEHA-PKQTFSAEFEVKEYVLPSFEVLVEPTEKFYYIH--GPKGLEVS
sp_P01027_CO3_MOUSEComplementC      AFYEHA-PKQIFSAEFEVKEYVLPSFEVRVEPTETFYYID--DPNGLEVS
sp_P12387_CO3_CAVPOComplementC      AFYENS-PKQVFSAEFEVKEYVLPSFEVLVEPTEKFYYID--DPKGLEVN
tr_Q9GKP1ComplementcomponentC3      AHYEDA-PQQVFSAEFEVKEYVLPSFEVQVEPSEKFYYID--DPNGLTVN
sp_Q00685_CO3_LAMJAComplementC      ARMSGA-PNINSSAEFDVREYILPTFEVKINPKQRVFHIN--DEE-FVVD
sp_P98094_CO3_EPTBUComplementC      SWMKDK-PQFNYTSGFKVEEYVLPTFDVSITSEQPYLHV---YDKAFTIH
sp_P01031_CO5_HUMANComplementC      AKYKED-FSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYK--NFKNFEIT
tr_Q8AYN9ComplementcomponentC5      ATCADT-FETTATAEFEVKEYVLPNISLHIQPEANYVSEK--NFESFQLK
tr_Q969A4ComplementcomponentC3      AHYGPE-MQLNVSTQFEVKEYVLPTYGVRIIPSNPYILPQ---DDVISGE
tr_Q03626Alpha_1_inhibitorIIIp      ILKQS---GVKEEHSFTVMEFVLPRFGVDVKVPNAISVYD----EIINVT
tr_Q9PVU4Alpha_2_macroglobulin      AYIG----DRMISHDFKVKKYVLPKFEVTVTAPETVSIDD----EFMAVE
tr_O44344ComplementcomponentC3      MDPSS----LSSQVTFVVKEYVLPTFSVSIETPKYILAG----ADSVVST
tr_Q8I7P1ComplementcomponentC3      ALYGHG-KVQNASIQFEVRKYVLPTFSVKLKGPSYILESD----PSITIK
tr_O97019AsC3protein_Halocynth      AVMNN---EVMATTSFVIDKYVLPTFDVKIEMEQHFILPG---QEIINGE
tr_Q8WPD8ComplementcomponentC3      VKFSSDGYTTSSTTSFKIDKYVLPTFDVALQLAQSHILTS---DPRITGT
tr_Q8TDJ3CD109_Homosapiens_Hum      VQVN----DQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNS----KHLNGT
tr_Q8IZJ3Alpha_2macroglobulinf      VEMQG----HAYNKSFEVQKYVLPKFELLIDPPRYIQDLD----ACETGT
tr_Q7Q7S6AgCP4019_Anophelesgam      VLVEGA---EIASKTFEVKKDVFSWFDVYIKPSVIPLEEH----QALNLT
                                                                                      

tn_CAD66666ComplementC4_Oncorh      ILAKYSYGESIKGAFHCRFGLKEKTQGPDGEKDKIVFIRGLELTGSIKDG
tr_Q9I932ComplementC4B_Cyprinu      IKALYTYGKTIDGGFHCRFGIKKDE--SENNAGEIEFIKGLEKTGSVKRG
sp_P01028_CO4_HUMANComplementC      IQARYIYGKPVQGVAYVRFGLLDED-------GKKTFFRGLESQTKLVNG
sp_P01029_CO4_MOUSEComplementC      IQARYIYGKPVQGVAYTRFALMDEQ-------GKRTFLRGLETQAKLVEG
tr_Q9I933ComplementC4A_Cyprinu      ISARYTYGKGVNGIAYIRFGLIDEK-------GNKIYLPGTEKQITVEDG
tn_BAC82347ComplementC4_Triaki      IVAKHTYGETVEGRVYVRFGILHES-------GNKSYIGGLEQELTMMNG
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      IEAKYLFGQKVDGNAFVMFGVMEDE--------KKTSIPASLQKVQIIKG
tn_AAQ74974ComplementC3_Ctenop      IEAKYLFGQKVEGNAFVMFGVMVDE--------KKTSIPASLQRVQIMKG
tr_Q9YIA7ComplementC3_S_Cyprin      IEAKYLFGQKVDGNAFVVFGVMNGE--------KKISIPTSLQKVQIIRG
tr_Q9YIB0ComplementC3_H1_Cypri      IEAKYLFGQKVDGNAFVMFGVMEDE--------KKTSIPASLQKVQIIKG
sp_P98093_CO3_ONCMYComplementC      ITARYLYGKEVTGTGYVVFGVITTES-------EKKSFPASLQRVEIKDG
tr_Q98TS6ComplementcomponentC3      IKAVYLFGKEVDGTAYVVFGVIQNG--------NKKSFPSSLQRVQIERG
tr_Q9PTY1ComplementcomponentC3      IKATYLFGEEVSGTAYVVFGVVLEG--------EKKSFPSSLQRISIDNG
tr_Q9IBH1OrlaC3_1protein_Oryzi      IKARYLFGQEVNGNAYVVFGVMDQG--------QKKSFPDSLSRVPIENG
tr_Q9IBH0OrlaC3_2protein_Oryzi      IKARYLFGQEVNGNAYVVFGVMDQG--------QKKSFPDSLSRVPIENG
sp_Q01833_CO3_NAJNAComplementC      ITARYLYGKKVEGVAFVVFGVKIDD--------AKKSIPDSLTRIPIIDG
tr_Q91132Cobravenomfactorprecu      ITARYLYGEEVEGVAFVLFGVKIDD--------AKKSIPDSLTRIPIIDG
tr_Q91588ComplementcomponentC3      IQAQYLYGKHVDGYAFVLFGIMKDN--------VKKGIPESLTRIRIDDG
tr_Q90633ComplementC3precursor      ITARYLYGKNLQGTAFVLFGVVVDD--------EKKTIPQSLQRVKVTDG
sp_P01024_CO3_HUMANComplementC      ITARFLYGKKVEGTAFVIFGIQDGE--------QRISLPESLKRIPIEDG
tr_Q80XP1Complementcomponent3_      IIAKFLYGKNVDGTAFVIFGVQDGD--------KKISLAHSLTRVVIEDG
sp_P01026_CO3_RATComplementC3p      ITARFLYGKNVDGTAFVIFGVQDED--------KKISLALSLTRVLIEDG
sp_P01027_CO3_MOUSEComplementC      IIAKFLYGKNVDGTAFVIFGVQDGD--------KKISLAHSLTRVVIEDG
sp_P12387_CO3_CAVPOComplementC      IIARFLYGKNVDGTAFVIFGVQDGD--------QRISLAQSLTRVVIEDG
tr_Q9GKP1ComplementcomponentC3      IIARFLYGESVDGTAFVIFGVQDGD--------QRISLSQSLTRVPIIDG
sp_Q00685_CO3_LAMJAComplementC      ITANYFNQELVSGTAYVRYFLENGD----------VPKLVDSSSTTLVAG
sp_P98094_CO3_EPTBUComplementC      IKAMHIYGKPVMGRAYVRYGVKHQS--------KRTLLSTSSALARFEQG
sp_P01031_CO5_HUMANComplementC      IKARYFYNKVVTEADVYITFGIREDL----KDDQKEMMQTAMQNTMLING
tr_Q8AYN9ComplementcomponentC5      ISAKYVHGAPVSSADISVTFGYSSPD-------ETVMIPATLSRYSLRNG
tr_Q969A4ComplementcomponentC3      VEALYTYGKGVDGFLDVKFGIIDLE---------GNRQLFAQLQTEVNGG
tr_Q03626Alpha_1_inhibitorIIIp      ACAIYTYGKPVPGHVKISLCHGNPS------------FSS---ETKSACK
tr_Q9PVU4Alpha_2_macroglobulin      VCGKYTYGQPVSGKSWVKVCRDIPR------------YSYRQDKHSPICV
tr_O44344ComplementcomponentC3      IIAEYVFGKPVIGRYTFKYGVVDNG-----------TVQELGTKQGLLGD
tr_Q8I7P1ComplementcomponentC3      VTSKYTYGKAVIGSVRVNLAVLDDAG---------KVERFSTSIHTLRNG
tr_O97019AsC3protein_Halocynth      IRAHYSYGEPVDGRYYLSCILKYGIVG--TEKEFFKIPKSPFGEAIISGG
tr_Q8WPD8ComplementcomponentC3      IYANYSYGEPVNGNVYLSATLQKLPGG--PAIKFYQIPPRITRTALFRNG
tr_Q8TDJ3CD109_Homosapiens_Hum      ITAKYTYGKPVKGDVTLTFLPLSFWG-----------KKKNITKTFKING
tr_Q8IZJ3Alpha_2macroglobulinf      VRARYTFGKPVAGALTINMTVNGVG-------YYSHEVGRPVLRTTKILG
tr_Q7Q7S6AgCP4019_Anophelesgam      IEAKYPFGKPVQGVAKVELYLEGDR--------------LDLSKDINVNG
                                                                                      

tn_CAD66666ComplementC4_Oncorh      EGSAVLQESKLREQLKSNLNTTLSDVVQSEAQLYMAVSVTDIISGELQEA
tr_Q9I932ComplementC4B_Cyprinu      HAKITVKISDLSQKLNS----SLEELAATQAQFYIAVTVTDILSGEVQES
sp_P01028_CO4_HUMANComplementC      QSHISLSKAEFQDALEKLN---MGITDLQGLRLYVAAAIIESPGGEMEEA
sp_P01029_CO4_MOUSEComplementC      RTHISISKDQFQAALDKIN---IGVRDLEGLRLYAATAVIESPGGEMEEA
tr_Q9I933ComplementC4A_Cyprinu      TAKTEVRTEDLKTASENNT-----QGRIEGYYLYIAVSVLEKASGNLEEA
tn_BAC82347ComplementC4_Triaki      EVNSSLTTQSLLEKSNLIS-----RNELVGWHLYMAVTTVESVSGEMEEL
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      EGTAELTNQMITK-------TFPNINQLVGRSIYVSVSLLTESGSEMVEA
tn_AAQ74974ComplementC3_Ctenop      EGTAELTREMITK-------TFPNINQLVGQSIYVSVSLLTESGSEMVEA
tr_Q9YIA7ComplementC3_S_Cyprin      EGTAELTSGMITK-------TFPNINQLVGQSIYVSVSVLTESGSEMVEA
tr_Q9YIB0ComplementC3_H1_Cypri      EGTAELTNQMITK-------TFPNINQLVGRSIYVSVSLLTESGSEMVEA
sp_P98093_CO3_ONCMYComplementC      KGVACLKKEHITQ-------TFPKIHDLVKQSIFVSVSVLTEGGGEMVEA
tr_Q98TS6ComplementcomponentC3      IGVVTLKKEHITK-------TYPPMDELVGTSIYVAVSVLTESGSEMVEA
tr_Q9PTY1ComplementcomponentC3      IGLVQLKRQQITQ-------SFQDINALVGNSLFVAVSVLTESGGEMVEA
tr_Q9IBH1OrlaC3_1protein_Oryzi      EGKVVLKREQITK-------TFQDINQLVGTSIFVSVSVLTESGSEMVEA
tr_Q9IBH0OrlaC3_2protein_Oryzi      EGKVVLKREQITK-------TFQDINQLVGTSIFVSVSVLTESGSEMVEA
sp_Q01833_CO3_NAJNAComplementC      DGEATLKRDTLRS-------RFQDLNQLVGHTLYVSVTVITESGSDMVVT
tr_Q91132Cobravenomfactorprecu      DGKATLKRDTFRS-------RFPNLNELVGHTLYASVTVMTESGSDMVVT
tr_Q91588ComplementcomponentC3      EGRAELKRKDLVK-------YFEKPEDMLQFSLYVTVSVVTETGSDMVEA
tr_Q90633ComplementC3precursor      DGQAVLPMAMLRQPF-----AN--LQELVGHSLYVTVTVLTESGSDMVEA
sp_P01024_CO3_HUMANComplementC      SGEVVLSRKVLLDGV-----QNLRAEDLVGKSLYVSATVILHSGSDMVQA
tr_Q80XP1Complementcomponent3_      VGDAVLTRKVLMEGV-----RPSNADALVGKSLYVSVTVILHSGSDMVEA
sp_P01026_CO3_RATComplementC3p      SGEAVLSRKVLMDGV-----RPSSPEALVGKSLYVSVTVILHSGSDMVEA
sp_P01027_CO3_MOUSEComplementC      VGDAVLTRKVLMEGV-----RPSNADALVGKSLYVSVTVILHSGSDMVEA
sp_P12387_CO3_CAVPOComplementC      SGEVVLSRQVLLDGV-----QPSRPEALVGKSLYVSVTVILHSGSDMVEA
tr_Q9GKP1ComplementcomponentC3      TGEATLSQGVLLNGV-----HYSSVNDLVGKSIYVSVTVILNSGSDMVEA
sp_Q00685_CO3_LAMJAComplementC      EGLSILKKEKLLK-------LFPNAKDLLAFSLTIKTTVLSSQAAETEEA
sp_P98094_CO3_EPTBUComplementC      EAMHTLRQKHILEQYP-------DPKLLLGQSLYVEASVISSDAGEIENS
sp_P01031_CO5_HUMANComplementC      IAQVTFDSETAVKEL-----SYYSLEDLNNKYLYIAVTVIESTGGFSEEA
tr_Q8AYN9ComplementcomponentC5      MQEVNLNIKSALSTMPDG--PQTLSAMKENSFLQVRVLLQESTGGITQEA
tr_Q969A4ComplementcomponentC3      FGFYEIDTQRIKD---------LDLWFPEGSRLYLEAAVTEEAGGLREMA
tr_Q03626Alpha_1_inhibitorIIIp      EEDSELDNNGCSTQEVNITEFQLKENYLKMHQAFHVNATVTEEGTGSEFS
tr_Q9PVU4Alpha_2_macroglobulin      NETTEMKRTGCAIHTLDVSAFLNSTYEDQLENSFHVEAIVTEEGTEITMT
tr_O44344ComplementcomponentC3      SGRAEVTLDDLSTDFG-----EDWFVRFRGRHFHANAIVHESATQFSEAS
tr_Q8I7P1ComplementcomponentC3      EADVIVSTDLLKAHAKIP-------WFPDGKRLVIEAKVIEQATGHEEKA
tr_O97019AsC3protein_Halocynth      KKKFSISTSKILEATN---FQSLEDFIALDGKVIILATVTGRAQAVYESD
tr_Q8WPD8ComplementcomponentC3      VKPFSIPLVELIGILQPG--ETLAQMSDQGAVVSIFATVNGEADGVMESA
tr_Q8TDJ3CD109_Homosapiens_Hum      SANFSFNDEEMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRN
tr_Q8IZJ3Alpha_2macroglobulinf      SQDFDICVRDMIP---------ADVPEHFRGRVSIWAMVTSVDGSQQVAF
tr_Q7Q7S6AgCP4019_Anophelesgam      SEQVMLAFNGGLELN-------------NEQQDVRVKVVVVEQDTDRTVM
                                                                                      

tn_CAD66666ComplementC4_Oncorh      EVS-LPVVSQRYTVDLSRTRSHYIPGVPLSVVVVVRLPNGSPAVGEPVRM
tr_Q9I932ComplementC4B_Cyprinu      EAF-LPIVLSQYIVDLSRTRSFYTPTFPLQAVVTVRQPNGSPAAGVQVNL
sp_P01028_CO4_HUMANComplementC      ELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKV
sp_P01029_CO4_MOUSEComplementC      ELTSWRFVSSAFSLDLSRTKRHLVPGAHFLLQALVQEMSGSEASNVPVKV
tr_Q9I933ComplementC4A_Cyprinu      ESSSVKIVTSPYVVDLSKTKTYFTPGGVFSVLATATYPDGKRVP--NLKF
tn_BAC82347ComplementC4_Triaki      ELSNIKFVSSPYVIDLSKTRRYFTPMSSFATVATVTYPDG------TPAV
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      ERRGIQIVTSPYTIHFRKTPQFFKPGMPFDVSVYVTNPDQTPAVNVEVEV
tn_AAQ74974ComplementC3_Ctenop      ERRGIQIVTSPYTIHFKKTPQFFKPGMPFDISVYVTNPDQTPAEDVEVEV
tr_Q9YIA7ComplementC3_S_Cyprin      ERRGIQIVTSPYSIHFKKTTQFFKPGMPFDVSVYVTNPDQTPAVNVEVEV
tr_Q9YIB0ComplementC3_H1_Cypri      ERRGIQIVTSPYTIHFRKTPQFFKPGMPFDVSVYVTNPDQTPAVNVEVEV
sp_P98093_CO3_ONCMYComplementC      EKRGIQIVTSPYSILFKRTPKYFKPGMPFDVSVYITNPDNSPAIGVEVEV
tr_Q98TS6ComplementcomponentC3      ELRSIQIVKSPYTIHFTKTPKYFKPGMSFDVAVEVVNPDGSPAQNVRVVV
tr_Q9PTY1ComplementcomponentC3      ELRGIQIVKSPYTIHFRKTPKYFKPGMTFDIVVEVTNPDETPAQGVAVVV
tr_Q9IBH1OrlaC3_1protein_Oryzi      ELRGIQIVKSPYTITFKRTPKYFKPGMSFDVAVEVLNPDESPAGNIPVVV
tr_Q9IBH0OrlaC3_2protein_Oryzi      ELRGIQIVTSPYTITFKKTPKYFKPGMSFDVAVEVLNPDESPAVNIPVVV
sp_Q01833_CO3_NAJNAComplementC      EQGGIHIVTSPYQIYFTKTPKYFKPGMPYELTVYVTNPDGSPAAHVPVVS
tr_Q91132Cobravenomfactorprecu      EQSGIHIVASPYQIHFTKTPKYFKPGMPYELTVYVTNPDGSPAAHVPVVS
tr_Q91588ComplementcomponentC3      EIEHISIVTTPYKILFTKTSKYFKPGMPFDMMVYVTNPDGSPARRIRVVV
tr_Q90633ComplementC3precursor      QRSGIRIVTSPYTIHFTHTPKYFKPGMPFDPTVYVTNPDNSPAAAGIPVK
sp_P01024_CO3_HUMANComplementC      ERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYR-VPVA
tr_Q80XP1Complementcomponent3_      ERSGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPASK-VLVV
sp_P01026_CO3_RATComplementC3p      ERSGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPARR-VPVV
sp_P01027_CO3_MOUSEComplementC      ERSGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPASK-VLVV
sp_P12387_CO3_CAVPOComplementC      ERSGIPIVTSPYQIHFTKTPKYFKPAMPFEIMVLVTNPDGSPAPH-VPVV
tr_Q9GKP1ComplementcomponentC3      ERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARH-IPVV
sp_Q00685_CO3_LAMJAComplementC      ELVGIKIVESRYQITATKTSRYFKPELPYFIQVEVRNADGSPSKEVDVVA
sp_P98094_CO3_EPTBUComplementC      ILDDIPIVASPYSIKSKWTVPFFKPGVPYIYKVLVLNPDGSPASGVPIKV
sp_P01031_CO5_HUMANComplementC      EIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSLDQLVGGVPVIL
tr_Q8AYN9ComplementcomponentC5      VLSNVKFVETPFTLNLIATPPFIKPGLPYSMRVLVKDPLGQPVQGVSVTT
tr_Q969A4ComplementcomponentC3      VLTSVRFETSPFRIGYDLTATHFKPGLPFLVKLTLTYPDTKPAQDIPVRV
tr_Q03626Alpha_1_inhibitorIIIp      GSGRIEVERTRNKFLFLKADSHFRHGIPFFVKIRLVDIKGDPIPNEQVFI
tr_Q9PVU4Alpha_2_macroglobulin      KSESISLTFEIGKCTLTDLPKTYEHGSVIEGKIKLSNFKGAPIQNKVVYL
tr_O44344ComplementcomponentC3      INTKAIFVDSPYKFSTKRTVQHFKAGLNLQVKLDLTFANGDVAPNVPVNV
tr_Q8I7P1ComplementcomponentC3      LDNTIYFTNTPLKISFKRSPRFFKPGVPFEIKVDVKYMNGQPANEIPIQI
tr_O97019AsC3protein_Halocynth      MVDDIIFSRTPYIIDMSRSAKFFFPRKIYEIKAIIKDVVSGHPISGVPVT
tr_Q8WPD8ComplementcomponentC3      VISNIPILRTPYRIDKSRALKYHTPGISYLLQVDVQDVVTHQNMANIPVR
tr_Q8TDJ3CD109_Homosapiens_Hum      VSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRN
tr_Q8IZJ3Alpha_2macroglobulinf      DDSTPVQRQLVDIRYSKDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQI
tr_Q7Q7S6AgCP4019_Anophelesgam      KEQSISVHKYPYRLTIVKDTLQFRPGHHFNCTVLLTYHDVSPARNVSLLV
                                                                                      

tn_CAD66666ComplementC4_Oncorh      HLPELQDGDQT-----------------VKTNQQGAVWHDFNLPNLDRDI
tr_Q9I932ComplementC4B_Cyprinu      RVSSTTEKYN------------------VITNKEGVAFQNFNLEGTPPSV
sp_P01028_CO4_HUMANComplementC      SATVSSPGSVPE-----------VQDIQQNTDGSGQVSIPIIIPQTISEL
sp_P01029_CO4_MOUSEComplementC      SATLVS-GSDSQ-----------VLDIQQSTNGIGQVSISFPIPPTVTEL
tr_Q9I933ComplementC4A_Cyprinu      TATVTIEGSPEH-----------ILKNEGWGNDMGDVAMPFQIPPQAKKL
tn_BAC82347ComplementC4_Triaki      NVPVTIEGGQ--------------VRN---TDEHGLVVFESEAPANASML
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      NP----------------------GGLRGQTRANGIAKVTVNTPGGSPTL
tn_AAQ74974ComplementC3_Ctenop      NP----------------------GTVNGNTKANGIAKVTVNTQGGSSRL
tr_Q9YIA7ComplementC3_S_Cyprin      VGS--------------------QGTVKGQTKHNGIAKVTVNTLGGSSTQ
tr_Q9YIB0ComplementC3_H1_Cypri      NP----------------------GGLRGQTRANGIAKVTVNTPGGSPTL
sp_P98093_CO3_ONCMYComplementC      TP----------------------DHAKGVTRANGFAKIPLNTVASATEL
tr_Q98TS6ComplementcomponentC3      NP----------------------GEVQGVTAANGLAKLTINTVAGNQRL
tr_Q9PTY1ComplementcomponentC3      DP----------------------GAVKGLTAANGFAKLTVNTMAGVARL
tr_Q9IBH1OrlaC3_1protein_Oryzi      TP----------------------GPVRGFTAANGMARLTINTATQDERL
tr_Q9IBH0OrlaC3_2protein_Oryzi      TP----------------------GPVRGSTAANGVARLTINTATTAGGL
sp_Q01833_CO3_NAJNAComplementC      EA---------------------IH-SEGTTLSDGTAKLILNTPLNIQSL
tr_Q91132Cobravenomfactorprecu      EA---------------------FH-SMGTTLSDGTAKLILNIPLNAQSL
tr_Q91588ComplementcomponentC3      EP---------------------GN-VEGSTQGDGTTRLTLNTPANINLL
tr_Q90633ComplementC3precursor      AD---------------------NFQGLVSTQRDGTAKLVLNMPANKNSV
sp_P01024_CO3_HUMANComplementC      VQG--------------------EDTVQSLTQGDGVAKLSINTHPSQKPL
tr_Q80XP1Complementcomponent3_      TQG--------------------SN-AKALTQDDGVAKLSINTPNSRQPL
sp_P01026_CO3_RATComplementC3p      TQG--------------------SD-AQALTQDDGVAKLSVNTPNNRQPL
sp_P01027_CO3_MOUSEComplementC      TQG--------------------SN-AKALTQDDGVAKLSINTPNSRQPL
sp_P12387_CO3_CAVPOComplementC      TQ---------------------GSNVQSLTQADGVARLSINTPNTRQPL
tr_Q9GKP1ComplementcomponentC3      TED--------------------FK-VRSLTQEDGVAKLSINTPDNRNSL
sp_Q00685_CO3_LAMJAComplementC      KVQVG------------------SATINPQKMRTDSNGLTSFTVTPPNVN
sp_P98094_CO3_EPTBUComplementC      SFSFDSSGN--------------WITQKRKTMDNGIAMQTINTARNSKKL
sp_P01031_CO5_HUMANComplementC      NAQTIDVNQETSDLDPS---------KSVTRVDDGVASFVLNLPSGVTVL
tr_Q8AYN9ComplementcomponentC5      RATITTADNQHHTLQFLGH----EDTLNVTSRGDGIAYFTCNIPANVKQA
tr_Q969A4ComplementcomponentC3      SATAIIPGQDPIVILGR-----NNEHNSDTTNQYGQASFTVDVPPGTQTL
tr_Q03626Alpha_1_inhibitorIIIp      KAQEAG------------------YTNATTTDQHGLAKFSIDTSSISGYS
tr_Q9PVU4Alpha_2_macroglobulin      LEGETWSSK---------------LLLNLTTDSDGLASFTLNTSSVSKED
tr_O44344ComplementcomponentC3      IATATLRDGSEELLRRPDIAG--GQEEISNTDDQGGVSMVLNVQSSITSI
tr_Q8I7P1ComplementcomponentC3      DAKTNDGTVVRERLAAG-------QVGGDKTNELGHGRFVVDIPKTFTIA
tr_O97019AsC3protein_Halocynth      IKAG------------------DAEAISKRSGDNGEIYHAVNLNSQRQQE
tr_Q8WPD8ComplementcomponentC3      IEITGPNGQ----------------RVIRNSTANQNGQVNYPHNFDTTGT
tr_Q8TDJ3CD109_Homosapiens_Hum      NVVITVTQRN-------------YTEYWSGSNSGNQKMEAVQKINYTVPQ
tr_Q8IZJ3Alpha_2macroglobulinf      KAELTPKDN------------IYTSEVVSQRGLVGFEIPSIPTSAQHVWL
tr_Q7Q7S6AgCP4019_Anophelesgam      EATG----------------EGVEHEQTYFTQHDGSINVLLHPTLSTQEV
                                                                                      

tn_CAD66666ComplementC4_Oncorh      TVEVTVDH-----QKITKDVNRTSSPGN----------TYLSVSVSQTFL
tr_Q9I932ComplementC4B_Cyprinu      SVQATVDG-----FMSTKEVRPMKSSTK----------SFLHISVTDKVL
sp_P01028_CO4_HUMANComplementC      QLSVSAGS----PHPAIARLTVAAPPS-----------GGPGFLSIERPD
sp_P01029_CO4_MOUSEComplementC      RLLVSAGS----LYPAIARLTVQAPPS-----------RGTGFLSIEPLD
tr_Q9I933ComplementC4A_Cyprinu      AVTVFAEGRDQEVIRSDKKMTAHAIKA-----------EGHSYLSLEVEH
tn_BAC82347ComplementC4_Triaki      SMKVMAGDGTLGKEFREEMVTAQVYQS-----------PSNSYLHIRTPH
tr_Q9YIA5ComplementC3_Q2_Cypri      DIKAKTKDPELRDE-QQAVRKMTAQAYETK------GGSQ-NYLHIGIDA
tr_Q9YIA9ComplementC3_H1_Cypri      AITAKTKDPEIKDERQQAEKRMTAQAYIPK------GGSN-NYLHIGIDA
tn_AAQ74974ComplementC3_Ctenop      EITAKTKDPQLIAE-QQAVKKMTAQAYVSK------GDSK-NYFHIGIDA
tr_Q9YIA7ComplementC3_S_Cyprin      EITAKTKDPQLRDN-QQAVKKMTAHAYIPK------DASKKNYLHIGIDA
tr_Q9YIB0ComplementC3_H1_Cypri      AITAKTKDPEIKDERQQAEKRMTAQAYIPK------GGSN-NYLHIGIDA
sp_P98093_CO3_ONCMYComplementC      VITVKTKDPGDPRQ-QTGGGTMKALPYR---------TSTKNFLHVGVDS
tr_Q98TS6ComplementcomponentC3      PINAKTNDPGILPER-QASASMVASPYT---------TTSKNYIHIGVDT
tr_Q9PTY1ComplementcomponentC3      PVTAKTNDPLIPLAR-QAEATMTALPYN---------TKSNNYIHIGVDT
tr_Q9IBH1OrlaC3_1protein_Oryzi      SISAKTDDPGISLNR-QAEATMQANQYSTN---------SKTYIHIGVDT
tr_Q9IBH0OrlaC3_2protein_Oryzi      SISAKTDDPNISPNR-QAQATMQANQYS--------T-NSKTYIHTGVDT
sp_Q01833_CO3_NAJNAComplementC      PITVRTNHGDLPRER-QAIKSMTATAYQ-------TQGGSENYLHVAITS
tr_Q91132Cobravenomfactorprecu      PITVRTNHGDLPRER-QATKSMTAIAYQ-------TQGGSGNYLHVAITS
tr_Q91588ComplementcomponentC3      PITVKTRDPTLPPGR-QATATMTATAYR-------PSKAQGNYLHISIAG
tr_Q90633ComplementC3precursor      PITVRTDQKDLPPER-QASRQIVAEAYQ-------SQGNSGNYLHLAVGA
sp_P01024_CO3_HUMANComplementC      SITVRTKKQELSEAE-QATRTMQALPYS-------TVGNSNNYLHLSVLR
tr_Q80XP1Complementcomponent3_      TITVRTKKDTLPESR-QATKTMEAHPYS-------TMHNSNNYLHLSVSR
sp_P01026_CO3_RATComplementC3p      TITVSTKKEGIPDAR-QATRTMQAQPYS-------TMHNSNNYLHLSVSR
sp_P01027_CO3_MOUSEComplementC      TITVRTKKDTLPESR-QATKTMEAHPYS-------TMHNSNNYLHLSVSR
sp_P12387_CO3_CAVPOComplementC      SVTVQTKKGGIPDAR-QAINTMQALPYT-------TMYNSNNYLHLSMPR
tr_Q9GKP1ComplementcomponentC3      PITVRTEKDGIPAAR-QASKTMHVLPYN-------TQGNSKNYLHLSLPR
sp_Q00685_CO3_LAMJAComplementC      QLTVTVRTDERHPSNEQGELVYTAQKYAS-----------ASYMHIDVTR
sp_P98094_CO3_EPTBUComplementC      NIKVQTEDERLEQSQ-QAEASFTIASYS---------SPSGSFIHLNAHR
sp_P01031_CO5_HUMANComplementC      EFNVKTDAPDLPEEN-QAREGYRAIAYS-------SLSQSYLYIDWTDNH
tr_Q8AYN9ComplementcomponentC5      EFTFETEDPSWSQD----PLKLKAESYV-------SINHRYLYISLPE-S
tr_Q969A4ComplementcomponentC3      TVTAKTEQVGLPVAH-QAQENFEATPYQ---------SPSGSYLLVRVLQ
tr_Q03626Alpha_1_inhibitorIIIp      LNIKVYHK---EESSCIHSSCTAERHAEEHHTAYAVYSLSKSYIYLDTEA
tr_Q9PVU4Alpha_2_macroglobulin      INLMASVYPAFQHRGYKTPFYSTDIKTVQLFQPATPYTPTLSELIIENID
tr_O44344ComplementcomponentC3      HIVAATHDPQYPNNQADISFEVSPGVSAN----------GHDYLVIRPQN
tr_Q8I7P1ComplementcomponentC3      HLVVKVRATISQGGKDIISEGRFQPSKYRS--------SGNNYLFVRFLT
tr_O97019AsC3protein_Halocynth      HILISTNHDTYKLEE-QSNITLSVDRYD-----------AKTELGIQLKK
tr_Q8WPD8ComplementcomponentC3      QFIKVTTAKPNLGAANQATVNITVEAYN---------SPGQRFLTVTPNP
tr_Q8TDJ3CD109_Homosapiens_Hum      SGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRD
tr_Q8IZJ3Alpha_2macroglobulinf      ETKVMALNGKPVGAQYLPSYLSLGSWYS----------PSQCYLQLQPPS
tr_Q7Q7S6AgCP4019_Anophelesgam      YLTISEKKYDLLYMKKLHTVQPLTNITMK--------------LQLRFPI
                                                                                      

tn_CAD66666ComplementC4_Oncorh      TLGQTLSVVF------------------------KVFNGPPED-----GF
tr_Q9I932ComplementC4B_Cyprinu      SAEEFLDVTF------------------------YVN-GNPED-----GQ
sp_P01028_CO4_HUMANComplementC      SRPPRVGDTL------------------------NLNLRAVGS-GATFSH
sp_P01029_CO4_MOUSEComplementC      PRSPSVGDTF------------------------ILNLQPVGIPAPTFSH
tr_Q9I933ComplementC4A_Cyprinu      QVLQPGEALK------------------------ATLRDITPQSAAKPTF
tn_BAC82347ComplementC4_Triaki      KVPEAGQDIY------------------------IEFQAITEAAGRSIDY
tr_Q9YIA5ComplementC3_Q2_Cypri      AELQIGDSVRVY----------------------LNTGQIPGVKDQDFTY
tr_Q9YIA9ComplementC3_H1_Cypri      AELQISDPMKVN----------------------LNTGQSPGVKDQDYTY
tn_AAQ74974ComplementC3_Ctenop      AELQIGDQMKVN----------------------LNTGQSPGVKDQDYTY
tr_Q9YIA7ComplementC3_S_Cyprin      AELQMGDSMKVF----------------------LNTGQSPGVKDQDYTY
tr_Q9YIB0ComplementC3_H1_Cypri      AELQISDPMKVN----------------------LNTGQSPGVKDQDYTY
sp_P98093_CO3_ONCMYComplementC      NELKIGDPIKID----------------------LNLG-PTTIPNHDLTY
tr_Q98TS6ComplementcomponentC3      AELELGDNLKIN----------------------LNLN-RKENHHTDITY
tr_Q9PTY1ComplementcomponentC3      AELELGDNLKVN----------------------LNLKKQSNQ-DTDITY
tr_Q9IBH1OrlaC3_1protein_Oryzi      PEVKLGDNLKVN----------------------LNLNKQPGG-NQDITY
tr_Q9IBH0OrlaC3_2protein_Oryzi      PEVKLGDNLKIN----------------------LILNKQPSG-SKDITY
sp_Q01833_CO3_NAJNAComplementC      TEIKPGDNLPVN----------------------FNVR-GNANSLNQIKY
tr_Q91132Cobravenomfactorprecu      TEIKPGDNLPVN----------------------FNVK-GNANSLKQIKY
tr_Q91588ComplementcomponentC3      SDIKPGENIPVN----------------------FNIRNTDAGVQKQIEH
tr_Q90633ComplementC3precursor      SQVQPGDNLPIN----------------------FHLKSNRDDVRKSVSY
sp_P01024_CO3_HUMANComplementC      TELRPGETLNVN---------------------FLLR-MDRAHEAK-IRY
tr_Q80XP1Complementcomponent3_      MELKPGDNLNVN---------------------FHLR-TDPGHEAK-IRY
sp_P01026_CO3_RATComplementC3p      VELKPGDNLNVN---------------------FHLR-TDAGQEAK-IRY
sp_P01027_CO3_MOUSEComplementC      MELKPGDNLNVN---------------------FHLR-TDPGHEAK-IRY
sp_P12387_CO3_CAVPOComplementC      TELKPGETINVN---------------------FHLR-SDPNQEAK-IRY
tr_Q9GKP1ComplementcomponentC3      VELKPGENLNVN---------------------FHLR-TDPGYQDK-IRY
sp_Q00685_CO3_LAMJAComplementC      IMR-LGETLNVF----------------------LTAK---TTQLNAVTH
sp_P98094_CO3_EPTBUComplementC      EVKSPGEHIVFD----------------------VFIK---SAAKDHVLH
sp_P01031_CO5_HUMANComplementC      KALLVGEHLNII----------------------VTPK---SPYIDKITH
tr_Q8AYN9ComplementcomponentC5      SVFEVGQYISIS----------------------VFFD---FRDFLSLKT
tr_Q969A4ComplementcomponentC3      RGPVPVDEAIDVE--------------------------AVVTKQNDIQS
tr_Q03626Alpha_1_inhibitorIIIp      GVLPCNQIHTVQ---------------------AHFILKGQVLGVLPQIV
tr_Q9PVU4Alpha_2_macroglobulin      QPLKCDAEFTVT---------------------IKYYFVGETVEDF-KTD
tr_O44344ComplementcomponentC3      TDDRNLNVDVSTD----------------------FLIQRIGTTGDQDID
tr_Q8I7P1ComplementcomponentC3      KPKVGQTVDAEAF----------------------------ALSEGKPNS
tr_O97019AsC3protein_Halocynth      QFVDVGDTVSVELR----------------------------LGDVSPTD
tr_Q8WPD8ComplementcomponentC3      HTVDVGREVHIT----------------------------LAFNQPTPAE
tr_Q8TDJ3CD109_Homosapiens_Hum      ENIKVG-----------------------------SPFELVVSGNKRLKE
tr_Q8IZJ3Alpha_2macroglobulinf      HPLQVGEEAYFSVKSTCPCNFTLYYEVAARGNIVLSGQQPAHTTQQRSKR
tr_Q7Q7S6AgCP4019_Anophelesgam      KQNEPIMLLAT--------------------------------CSERMTF
                                                                                      

tn_CAD66666ComplementC4_Oncorh      IYYMVFSRGVLIKQGSVKSG---------DLTKVQLPITPDMTPSFRLIG
tr_Q9I932ComplementC4B_Cyprinu      IYYMILSRGMLRSASSAASG---------SVVKKSIRISPEMIPSFRVIA
sp_P01028_CO4_HUMANComplementC      YYYMILSRGQIVFMNREPKR---------TLTSVSVFVDHHLAPSFYFVA
sp_P01029_CO4_MOUSEComplementC      YYYMIISRGQIMAMGREPRK---------TVTSVSVLVDHQLAPSFYFVA
tr_Q9I933ComplementC4A_Cyprinu      IYFMVWSKGQIVQIGRVPRT---------EITTVNVNVNVEMVPSFRLVA
tn_BAC82347ComplementC4_Triaki      YYYILINKGRVIASDRIHKA---------DPTKLRLQVTLDMVPTVRLLA
tr_Q9YIA5ComplementC3_Q2_Cypri      M---ILSKGQIVKVDRFKRK-------GQSLVTLPVTVTKDMVPSFRFVA
tr_Q9YIA9ComplementC3_H1_Cypri      M---ILSKGQIVKVDRFKRK-------GQSLVTLPVTVTKDMVPSFRFVA
tn_AAQ74974ComplementC3_Ctenop      M---ILSKGQIVHADRFKRK-------GQALVTLSLPVTKDMVPSFRFVA
tr_Q9YIA7ComplementC3_S_Cyprin      M---ILSKGQIVSVDRFKRR-------GQSLVSLPVPVTKDMVPSFRFVA
tr_Q9YIB0ComplementC3_H1_Cypri      M---ILSKGQIVKVDRFKRK-------GQSLVTLPVTVTKDMVPSFRFVA
sp_P98093_CO3_ONCMYComplementC      M---FLSRGQLVKVGRFKRQ-------GNALVTLSVPVSKELLPSFRIVA
tr_Q98TS6ComplementcomponentC3      L---ILSRGQAGEQRPYRAE-------GQILISLIVPVTKEMLASFRIIA
tr_Q9PTY1ComplementcomponentC3      L---ILSRGQLIQSGRYRTR-------GQVLISLIIPITKVMLPSFRIVA
tr_Q9IBH1OrlaC3_1protein_Oryzi      L---ITSRGQLVKFGRYKTR-------GQVLISLIIPVTQEMLPSFRIIA
tr_Q9IBH0OrlaC3_2protein_Oryzi      L---ITSRGQLVKFGRYKTI-------GQVLISLIIPVTQEMLPSFRIIA
sp_Q01833_CO3_NAJNAComplementC      FTYLILNKGKIFKVGRQPRRD------GQNLVTMNLHITPDLIPSFRFVA
tr_Q91132Cobravenomfactorprecu      FTYLILNKGKIFKVGRQPRRD------GQNLVTMNLHITPDLIPSFRFVA
tr_Q91588ComplementcomponentC3      FTYLIISRGRILKVGRQQRQP------GQPFVTMSIPVTDTLIPSFRIVA
tr_Q90633ComplementC3precursor      FTYLILSKGHIVHVGRQPREG------DQSLVTMSLPVTANLIPSFRIVA
sp_P01024_CO3_HUMANComplementC      YTYLIMNKGRLLKAGRQVREP------GQDLVVLPLSITTDFIPSFRLVA
tr_Q80XP1Complementcomponent3_      YTYLVMNKGKLLKAGRQVREP------GQDLVVLSLPITPEFIPSFRLVA
sp_P01026_CO3_RATComplementC3p      YTYLVMNKGKLLKAGRQVREP------GQDLVVLSLPITPEFIPSFRLVA
sp_P01027_CO3_MOUSEComplementC      YTYLVMNKGKLLKAGRQVREP------GQDLVVLSLPITPEFIPSFRLVA
sp_P12387_CO3_CAVPOComplementC      YTYLIMNKGKLLKVGRQPREP------GQALVVLPMPITKELIPSFRLVA
tr_Q9GKP1ComplementcomponentC3      FTYLIMNKGKLLKVGRQPRES------GQVVVVLPLTITTDFIPSFRLVA
sp_Q00685_CO3_LAMJAComplementC      FTYMVLTRGVIVKTNRKTKES------GGGPSNVRIPITPDMAPRFRFLA
sp_P98094_CO3_EPTBUComplementC      FNYLMISNGKIHNFLQEGRK--------GDTTSVSLLLTPELVPQFRLVA
sp_P01031_CO5_HUMANComplementC      YNYLILSKGKIIHFGTREKFS------DASYQSINIPVTQNMVPSSRLLV
tr_Q8AYN9ComplementcomponentC5      FSYQIISRGKVVQFDT-VKWD------GVKNQNLNIKITPDMVPSARLVV
tr_Q969A4ComplementcomponentC3      YNYMVVTRGQVTLQGKIVRQG-------GVLKTITFRTSAVMAPISRLIV
tr_Q03626Alpha_1_inhibitorIIIp      FHYLVMAQGSILQTGNHTHQVEPGVSQVQGNFALEIPVEFSMVPVAKMLI
tr_Q9PVU4Alpha_2_macroglobulin      IVYMVLSRGVIVHHGYEKVEVKSSNGAASGTVSFKLSIGADLAPAVQILT
tr_O44344ComplementcomponentC3      LHFLCITGGKVVLEGVQRSIS-------AAGTNLAITIRAYMAPQMRLIV
tr_Q8I7P1ComplementcomponentC3      LTYMVIANGKVVFQGQINRDLG-------VLTTVRIRVTSAMIPQARFVA
tr_O97019AsC3protein_Halocynth      IRYYVVSRGEIVYAQTKEITE-------NGDVAIDFEVTHKMVPFSRVVA
tr_Q8WPD8ComplementcomponentC3      IRFYVVSRGSVVLVGRIVPPAN------SHNIVQIIQVTQAMVPSMRVIA
tr_Q8TDJ3CD109_Homosapiens_Hum      LSYMVVSRGQLVAVGKQNST------------MFSLTPENSWTPKACVIV
tr_Q8IZJ3Alpha_2macroglobulinf      AAPALEKPIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLV
tr_Q7Q7S6AgCP4019_Anophelesgam      LAYYVVSKSNIVDAGYIGQLR-------QKKIVFEISATEKMLPKATIYV
                                                                       .       .   .  

tn_CAD66666ComplementC4_Oncorh      YYYDQ----KGD---IITDSVWVDVDD-ACEGTVKVKSK--DEYLPGN--
tr_Q9I932ComplementC4B_Cyprinu      YYYDT----NGD---AIANSVWVDVED-KCEGKLEIKLHGNHNYQPDD--
sp_P01028_CO4_HUMANComplementC      FYYHG----DHP----VANSLRVDVQAGACEGKLELSVDGAKQYRNGE--
sp_P01029_CO4_MOUSEComplementC      YFYHQ----GHP----VANSLLINIQSRDCEGKLQLKVDGAKEYRNAD--
tr_Q9I933ComplementC4A_Cyprinu      YYFTD----SSPNEKIVADSVWVDVKD-ICKGKVEIDP-LPEIKPAT---
tn_BAC82347ComplementC4_Triaki      YYYTQ----AGERKEIVANSVWIDVKD-ECEGQIEIKEENKSYGPGG---
tr_Q9YIA5ComplementC3_Q2_Cypri      YY-------HVGSSEVVSDSVWVDVKD-TCMGTLQIKVKDKLNTY-----
tr_Q9YIA9ComplementC3_H1_Cypri      YY-------HVG-LEVVSDSVWVDVKD-TCMGKLQIKVKNKMNTY-----
tn_AAQ74974ComplementC3_Ctenop      YY-------HVGPSEVVSDSVWVDVKD-TCMGTLKLQVKNKMNIY-----
tr_Q9YIA7ComplementC3_S_Cyprin      YY-------HVGSSEVVSDSVWVDVKD-TCMGKLQVKVKDKMNTY-----
tr_Q9YIB0ComplementC3_H1_Cypri      YY-------HVG-LEVVSDSVWVDVKD-TCMGKLQIKVKNKMNTY-----
sp_P98093_CO3_ONCMYComplementC      YY-------HVGAADLVADSVWVDIKV-SCMGSLKVTSTRPKASY-----
tr_Q98TS6ComplementcomponentC3      YY-------HTMSYEVVSDSVWVDVKD-SCMGSLRLEAVSAKNSY-----
tr_Q9PTY1ComplementcomponentC3      YY-------HLDDNEVVSDSVWVDVKD-SCMGTLKLESSRPAPSY-----
tr_Q9IBH1OrlaC3_1protein_Oryzi      FY-------HPSDNEVVSDSVWVDVKD-SCMGSLTLEPKTPAASY-----
tr_Q9IBH0OrlaC3_2protein_Oryzi      FY-------HPSHNEVVSDSVWADVTD-SCMGSLTLEPTRPGTAN-----
sp_Q01833_CO3_NAJNAComplementC      YY---QVGNN----EIVADSVWVDVKD-TCMGTLVVKGASSRDDR-----
tr_Q91132Cobravenomfactorprecu      YY---QVGNN----EIVADSVWVDVKD-TCMGTLVVKG----DNL-----
tr_Q91588ComplementcomponentC3      YY---IVSAGG-GRDIVSDSLWVDVVD-DCMGTLSVTGDKDRDNT-----
tr_Q90633ComplementC3precursor      YY---HVK----PGEIIADSVWVDVKD-TCMGSLVVRGASEADN----R-
sp_P01024_CO3_HUMANComplementC      YYT---LIGASGQREVVADSVWVDVKD-SCVGSLVVKSG-QSEDR-----
tr_Q80XP1Complementcomponent3_      YYT---LIGASGQREVVADSVWVDVKD-SCIGTLVVKGD-PRDN------
sp_P01026_CO3_RATComplementC3p      YYT---LIGANGQREVVADSVWVDVKD-SCVGTLVVKGD-PRDNR-----
sp_P01027_CO3_MOUSEComplementC      YYT---LIGASGQREVVADSVWVDVKD-SCIGTLVVKGD-PRDN------
sp_P12387_CO3_CAVPOComplementC      YYT---LIGASAQREVVADSVWADVRD-SCVGTLVVKGGSGKDGQDKRQ-
tr_Q9GKP1ComplementcomponentC3      YYT---LIAANGQREVVADSVWVDVKD-SCVGTLVVKGG-GKQDK-----
sp_Q00685_CO3_LAMJAComplementC      YY-------ILPGGEIVADSVTVEVTE-LCKSQVSLSLKGRPTLEP----
sp_P98094_CO3_EPTBUComplementC      FFILP-------SGELVADSIIIDVKD-SCHAKLSLDVAGGKRLFS----
sp_P01031_CO5_HUMANComplementC      YY----IVTGEQTAELVSDSVWLNIEE-KCGNQLQVHLSP--DADAYS--
tr_Q8AYN9ComplementcomponentC5      YY----VLYGEEKAELVADSTWIDVKA-KCVNNLNVDISTPDSQHVYK--
tr_Q969A4ComplementcomponentC3      YYIN-------LQGEVVADSTLLEIEN-VCRNKVMVSSTEDVEPQ-----
tr_Q03626Alpha_1_inhibitorIIIp      YTILP-------DGEVIADSVTFQVEK-CLRNKVHLSFSPSQSLP-----
tr_Q9PVU4Alpha_2_macroglobulin      YCVLP-------SENVIAGSKKIDIEK-CFKNKVSLQFSPAKAVP-----
tr_O44344ComplementcomponentC3      YY-------VTMDGSVIADSLLLGVEE-KCRQDPQLSLDILPRNVGPERD
tr_Q8I7P1ComplementcomponentC3      YYRVN--------NELVADSTIMEVEEELPNQVSFFGDQHSQKIP-----
tr_O97019AsC3protein_Halocynth      YYFLN--------GEVTANSAWFDVTD-QCLEEITIEPQSQTAKP-----
tr_Q8WPD8ComplementcomponentC3      YFLHG--------AEVVSNSAFVNVVN-RCETELTVTTNRNTVKP-----
tr_Q8TDJ3CD109_Homosapiens_Hum      YYIED-------DGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPS-----
tr_Q8IZJ3Alpha_2macroglobulinf      FYVRE-------NGEGVADSLQFAVET-FFENQVSVTYSANETQP-----
tr_Q7Q7S6AgCP4019_Anophelesgam      TS--------AFENILIWDALEIDLR--PLSNDLEIRVNKLKAKP-----
                                                      .     :                         

tn_CAD66666ComplementC4_Oncorh      ----TAKLEIDLNGQK-AKVALLAVDKAIYALN--AQNKLTPKQVFSSMQ
tr_Q9I932ComplementC4B_Cyprinu      ----TAELDIDVGTQKNAKVALLVVDKAIYALG--AQNKLTPKQVFTAMQ
sp_P01028_CO4_HUMANComplementC      ------SVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMN
sp_P01029_CO4_MOUSEComplementC      ------MMKLRIQTDSKALVALGAVDTALYAVGGRSHKPLDMSKVFEVIN
tr_Q9I933ComplementC4A_Cyprinu      ------KFEVTVRTDPKAKVALAAVDSAVYILN---KNKLGLQKMFEYMN
tn_BAC82347ComplementC4_Triaki      ------VYDLQFSTNDAANVSFVAVDAAMYILNN--KNKLTPRKVFEQMN
tr_Q9YIA5ComplementC3_Q2_Cypri      --DTGDEVKLQITGDPGAKVGLVVVDKAVN------KNRLTQTQIWDVIE
tr_Q9YIA9ComplementC3_H1_Cypri      --GTGDEVKLQITGDPGAKVGLVVVDKAVQVLN---KNRLTQTQIWDVIE
tn_AAQ74974ComplementC3_Ctenop      --STGDEVKLQITGESWSSWSGGGQGCACP------QEQIHSSQIWDRIE
tr_Q9YIA7ComplementC3_S_Cyprin      --DTGDEVKLEITGDPGAKVGLVVVDKAVQVLN---KNRLTQTQIWDVIE
tr_Q9YIB0ComplementC3_H1_Cypri      --GTGDEVKLQITGDPGAKVGLVVVDKAVQVLN---KNRLTQTQIWDVIE
sp_P98093_CO3_ONCMYComplementC      --EPRRAFSLTITGDPGAKVGLVAVDKGVYVLNS--KHRLTQTKIWDTIE
tr_Q98TS6ComplementcomponentC3      --EPRKMFVLKVTGDPDATVGLVAVDKGVYVLNN--KHRLTQKKVWDIVE
tr_Q9PTY1ComplementcomponentC3      --EPRKMFGLKVTGVPEAMVGLVAVDKGVYVLNN--KHRITQKKVWDIIE
tr_Q9IBH1OrlaC3_1protein_Oryzi      --EPRKMFSLKVSGDPGATVGLVAVDKGVYVLNS--KHRLTQKKIWDEVE
tr_Q9IBH0OrlaC3_2protein_Oryzi      --EPRRLFGLKVSGDPGATVGLVAVDKGVYVLNS--KHRLTQKKIWDEVE
sp_Q01833_CO3_NAJNAComplementC      IQKPGAAMKIKLEGDPGARVGLVAVDKAVYVLND--KYKISQAKIWDTIE
tr_Q91132Cobravenomfactorprecu      IQMPGAAMKIKLEGDPGARVGLVAVDKAVYVLND--KYKISQAKIWDTIE
tr_Q91588ComplementcomponentC3      IQTPGSPMRLKLRADHKAYVGLVAVDKGVYVLNS--KFKITQKKVWDSVE
tr_Q90633ComplementC3precursor      VHEPRTPMRLHIEGDHKAHVGLVAVDKAVYVLNK---NKLTQSKVWDTVE
sp_P01024_CO3_HUMANComplementC      QPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNK--KNKLTQSKIWDVVE
tr_Q80XP1Complementcomponent3_      HLAPGQQTTLRIEGNQGARVGLVAVDKGVFVLNK--KNKLTQSKIWDVVE
sp_P01026_CO3_RATComplementC3p      QPAPGHQTTLRIEGNQGARVGLVAVDKGVFVLNK--KNKLTQSKIWDVVE
sp_P01027_CO3_MOUSEComplementC      HLAPGQQTTLRIEGNQGARVGLVAVDKGVFVLNK--KNKLTQSKIWDVVE
sp_P12387_CO3_CAVPOComplementC      QHLPRQQMTLRIEGNQGARVGLVAVDKGVFVLNK--KHKLTQSKIWDVVE
tr_Q9GKP1ComplementcomponentC3      QHRPGQQMTLEIQGERGARVGLVAVDKGVFVLNK--KNKLTQRRIWDVVE
sp_Q00685_CO3_LAMJAComplementC      ----KAMLTLDLIGEPDARVGLLAVDQAVYAVNR--KHRLTQDRVWKAME
sp_P98094_CO3_EPTBUComplementC      ---PRDNVNFDLSGESDSWVAVGVVDKAAYVLDK--KNKLTANKVYKAME
sp_P01031_CO5_HUMANComplementC      -PGQTVSLNMATG--MDSWVALAAVDSAVYGVQR--GAKKPLERVFQFLE
tr_Q8AYN9ComplementcomponentC5      -PKDELKLRVSTKSREESLVVFSAVDTALYNLKS--YDKDPLKKVLQHVE
tr_Q969A4ComplementcomponentC3      -----EQANIEVNADPNSLVGLLAVDQAVYLLNN--YNRLTSQKMFQAMA
tr_Q03626Alpha_1_inhibitorIIIp      ----ASQTHMRVTASPQSLCGLRAVDQSVLLLKP--EAELSPSLIYDLPG
tr_Q9PVU4Alpha_2_macroglobulin      ----GEKNTLQLSAQPGSLCGLSAVDQSILILES--GKRLDTDKIFNLLP
tr_O44344ComplementcomponentC3      VYEPNGQIQVEVTAPIDSNVGLLAVDKAVYLLRD--KDRMGKQKMYERMR
tr_Q8I7P1ComplementcomponentC3      ----GDSHAITIQSSPHSNVGILAVDQSVYLLRN--DKHLTSDEVYKRMK
tr_O97019AsC3protein_Halocynth      ----GEDFKFTVSGPANAKIEFSAVDRAAYFVHN--SSRLTRNTLWRKME
tr_Q8WPD8ComplementcomponentC3      ----GAPITYTIEGAQNADVLLYGVDRAAYFLYN--GSRLTRNSMFSDMA
tr_Q8TDJ3CD109_Homosapiens_Hum      ----EKVSLRISVTQPDSIVGIVAVDKSVNLMNAS--NDITMENVVHELE
tr_Q8IZJ3Alpha_2macroglobulinf      ----GEVVDLRIRAARGSCVCVAAVDKSVYLLRS--GFRLTPAQVFQELE
tr_Q7Q7S6AgCP4019_Anophelesgam      ----GQEIELELKGRPSAYVGLAAYDKGLLAFAN------HLDPFWEDVT
                                                     :       . .                .     

tn_CAD66666ComplementC4_Oncorh      SYDLGCSYGGGSDTASVLNDAGLSFISN-SHVLS-------R-MRKGFNC
tr_Q9I932ComplementC4B_Cyprinu      SYDLGCSYGSGENAAAVFNDAGLAFISHSTSFRS-------M-MRKGFSC
sp_P01028_CO4_HUMANComplementC      SYDLGCGPGGGDSALQVFQAAGLAFSDGDQWTLS-------R-KRLSCPK
sp_P01029_CO4_MOUSEComplementC      SYNVGCGPGGGDDALQVFQDAGLAFSDGDRLTQT-------R-EDLSCPK
tr_Q9I933ComplementC4A_Cyprinu      SYDLACSIGGGEDSSAVLQRAGLTFMCNCDMETP-------TPLDHKCYK
tn_BAC82347ComplementC4_Triaki      SYDLGCFYGGGVNSVGVFKDAGLSFISDVDVAS----------IRHEYSC
tr_Q9YIA5ComplementC3_Q2_Cypri      KHDIGCTAGGGRDSMGVFTDAGLMFESNTAGG---------TNTRTTPDC
tr_Q9YIA9ComplementC3_H1_Cypri      KHDTGCTAGGGKDSMGVFTDAGLMFESSTAGG---------TNTRTMPEC
tn_AAQ74974ComplementC3_Ctenop      QHDTGCTQKVKVTVWG-FSVMQVCFESHTAGG---------TNTRTSSVC
tr_Q9YIA7ComplementC3_S_Cyprin      KHDTGCTAGGGRDRMGVFTDAGLMFQSNTAGG---------TNIRTMPEC
tr_Q9YIB0ComplementC3_H1_Cypri      KHDTGCTAGGGKDSMGVFTDAGLMFESNGAGG---------TNTRTMPEC
sp_P98093_CO3_ONCMYComplementC      KHDTGCTAGGGADNMGVFYDAGLVFETNTAKG---------TGIRTDPSC
tr_Q98TS6ComplementcomponentC3      KYDTGCTPGGGKDGMGVFYDAGLMFEFNTASGDSG------TPYRRELKC
tr_Q9PTY1ComplementcomponentC3      KYDTGCTPGGGKNSMSVFYDAGLLFESSAASG---------TPYRQELKC
tr_Q9IBH1OrlaC3_1protein_Oryzi      KFDTGCTPGGGKNGLSVFFDAGLLFESSTASG---------TVYRQEKKC
tr_Q9IBH0OrlaC3_2protein_Oryzi      KFDTGCTPGGGKNGLSVFFDSGLLFESSTASG---------TVYRQEKKC
sp_Q01833_CO3_NAJNAComplementC      KSDFGCTAGSGQNNLGVFEDAGLALTTS-TNLN--------TKQRSAAKC
tr_Q91132Cobravenomfactorprecu      KSDFGCTAGSGQNNLGVFEDAGLALTTS-TNLN--------TKQRSAAKC
tr_Q91588ComplementcomponentC3      KSDIGCTPGSGANSEGVFSDAGLALQTS-FGIN--------TAQRSDAQC
tr_Q90633ComplementC3precursor      NSDIGCTPGSGRNQVGVFADAGLSLTSN-VNIN--------TEQRSEVQC
sp_P01024_CO3_HUMANComplementC      KADIGCTPGSGKDYAGVFSDAGLTFTSS-SGQQ--------TAQRAELQC
tr_Q80XP1Complementcomponent3_      KADIGCTPGSGKNYAGVFMDAGLAFKTS-QGLQ--------TEQRADLEC
sp_P01026_CO3_RATComplementC3p      KADIGCTPGSGKNYAGVFMDAGLTFKTN-QGLQ--------TDQREDPEC
sp_P01027_CO3_MOUSEComplementC      KADIGCTPGSGKNYAGVFMDAGLAFKTS-QGLQ--------TEQRADLEC
sp_P12387_CO3_CAVPOComplementC      KADIGCTPGSGKDYAGVFTDAGLSFKSSKAGLQ--------TAQREGLDC
tr_Q9GKP1ComplementcomponentC3      KADIGCTPGSGKDFAGVFTDAGLAFKSS-KGLQ--------TPQRADLEC
sp_Q00685_CO3_LAMJAComplementC      TFDTGCTAEGGAGRPGVFSDAGLALITSKGLN---------TTDRSEIGC
sp_P98094_CO3_EPTBUComplementC      ASDLGCSVGSGKTGPLVFRDAGLAIMAKEISG---------MDDVKDPGC
sp_P01031_CO5_HUMANComplementC      KSDLGCGAGGGLNNANVFHLAGLTFLTN-------------ANADDSQEN
tr_Q8AYN9ComplementcomponentC5      RSDLGCGRGGGKNNADVFDRVGLMFITN-------------ANAKTSSTE
tr_Q969A4ComplementcomponentC3      KYDQGCGPGGGQDSANVFKDAGVTVLTNTQLSP---------AVRSNAGC
tr_Q03626Alpha_1_inhibitorIIIp      MQDSNFIPSSY------------------------------HPFEDEYDC
tr_Q9PVU4Alpha_2_macroglobulin      VQSVSDYP---------------------------------YSVEDEQEC
tr_O44344ComplementcomponentC3      SYDTGCGPGGGQNTAQIFKDCGMTVLTNAGLDVP---------IREDVEC
tr_Q8I7P1ComplementcomponentC3      SHDLGCGSGAGADNKDVLNRGGLAVMTTINNLK--------TDTRAEYSC
tr_O97019AsC3protein_Halocynth      AYDTGCSRKGGKNAMSVFKEAGLLYQSANINNQ---------DLHTDVCA
tr_Q8WPD8ComplementcomponentC3      AYDQGCVSNGGSDGPNVFFGAGLTLTTPTHKPG--------ALDTLDCTA
tr_Q8TDJ3CD109_Homosapiens_Hum      LYNTGYYLGMFMNSFAVFQECGLWVLTD----------------------
tr_Q8IZJ3Alpha_2macroglobulinf      DYDVSDSFGVSREDGPFWWAGLTAQRRRRSSVFPWPWGITKDSGFAFTET
tr_Q7Q7S6AgCP4019_Anophelesgam      QLFDYS--------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      ESGFRRQRRS-LDLQEQMVSIKSSYSDAKLQECCSHGLSLIAMLRTCQQR
tr_Q9I932ComplementC4B_Cyprinu      ESGFRRNKRS-IDIQAEMAKKEAAFKKAELQKCCRHGFTLIPMKFTCEER
sp_P01028_CO4_HUMANComplementC      EK-TTRKKRN-VNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQR
sp_P01029_CO4_MOUSEComplementC      EK-KSRQKRN-VNFQKAVSEKLGQYSSPDAKRCCQDGMTKLPMKRTCEQR
tr_Q9I933ComplementC4A_Cyprinu      SKPEPRVRRT-ADYVKKFNNVVNSFKGS-DRKCCLDGVRPNKMHTSCDER
tn_BAC82347ComplementC4_Triaki      KNEVRRQRRA-LNLQRQYAGKLNEYTDSRLRKCYTDGLTKILMPHSCEER
tr_Q9YIA5ComplementC3_Q2_Cypri      PFLSKRRRRS-D--------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      PKTSKRKRRA-ESLLQITSTLAGKYTGELK-QCCVDGMRDNKLGYTCERR
tn_AAQ74974ComplementC3_Ctenop      PVPAKRKRRA-ESLLQITSTLVGKYSGELK-QCCIDGMRENKLGYTCERR
tr_Q9YIA7ComplementC3_S_Cyprin      PKPSKRRRRA-ESLLKITSTLAEKYSGELK-QCCVDGMRENKLGYTCDRR
tr_Q9YIB0ComplementC3_H1_Cypri      PKTSKRKRRA-ESLLQITSTLAGKYTGELK-QCCVDGMRDNKLGYTCERR
sp_P98093_CO3_ONCMYComplementC      PVSS-RRRRA-VTISDVITSMASKYHGLAK-ECCVDGMRDNTMGYTCDRR
tr_Q98TS6ComplementcomponentC3      PAPS-RRKRA-TTIMDVTTSLLSQYKDQLQSDCCLDGMKETLLNYTCERR
tr_Q9PTY1ComplementcomponentC3      PVPARR-KRA-TTVMNVTTTLVNKYKNELQRECCSEGMKETILSYTCEVR
tr_Q9IBH1OrlaC3_1protein_Oryzi      AAPSRR-RRA-STIMDVRTTLLSQYKEDLQRECCLDGMKDSPVSYTCERR
tr_Q9IBH0OrlaC3_2protein_Oryzi      AAPFRR-RRA-STIMDVRTTLLSQYNEDFQRECCLDGMKDSPVSYTCERR
sp_Q01833_CO3_NAJNAComplementC      PQPANRRRRSSVLLLDSKASKAAQFQDQGLRKCCEDGMHENPMGYTCEKR
tr_Q91132Cobravenomfactorprecu      PQPANRRRRSSVLLLDSNASKAAEFQDQDLRKCCEDVMHENPMGYTCEKR
tr_Q91588ComplementcomponentC3      PAPAQRRKRSSVALIEIKSGKASEYKDK-AKKCCLDGMQENLMGHTCDRR
tr_Q90633ComplementC3precursor      AKPAKRKRRS-VRLIKHKGTKMAEYSDKNLRKCCEDGIRKNLMGYSCEKR
sp_P01024_CO3_HUMANComplementC      PQPAARRRRS-VQLTEKRMDKVGKYP-KELRKCCEDGMRENPMRFSCQRR
tr_Q80XP1Complementcomponent3_      TKPAARRRRS-VQLMERRMDKAGQYTDKGLRKCCEDGMRDIPMRYSCQRR
sp_P01026_CO3_RATComplementC3p      AKPAARRRRS-VQLMERRMDKAGQYTDKGLRKCCEDGMRDIPMPYSCQRR
sp_P01027_CO3_MOUSEComplementC      TKPAARRRRS-VQLMERRMDKAGQYTDKGLRKCCEDGMRDIPMRYSCQRR
sp_P12387_CO3_CAVPOComplementC      PKPAARRRRS-VQLMERRMDKAGKYKSKELRRCCEDGMRENPMQFSCQRR
tr_Q9GKP1ComplementcomponentC3      PKPAARKRRS-VQLMEKRMDKLGQYS-KDVRRCCEHGMRDNPMKFSCQRR
sp_Q00685_CO3_LAMJAComplementC      PKVPSRKPRQ---LSMLQIRREAEKYTQEFRKCCVDGLKMSPTGQGCEER
sp_P98094_CO3_EPTBUComplementC      PNGHTRRKRE---LVLEIAIEKASTYPAELRKCCRDAAIESPLRLSCEER
sp_P01031_CO5_HUMANComplementC      DEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDG-ACVNNDETCEQR
tr_Q8AYN9ComplementcomponentC5      G-VCSDLVRPKRSVDLAQTFEQMAKSFGLYQHCCTSGTESSSMLETCKHR
tr_Q969A4ComplementcomponentC3      GGQSRRKRDL-----QNSLEAKVMEFNETLQPCCMDGQQWDPLGRSCLQR
tr_Q03626Alpha_1_inhibitorIIIp      LMYQPRDTEELTYSVPYGREKDVYRYVRDMGLTAFTNLKIKHPTYCYEMN
tr_Q9PVU4Alpha_2_macroglobulin      LHVRPR---------RAVLTDNAFESLKSVGLKMATNLAVRVPQCLLYKG
tr_O44344ComplementcomponentC3      MDEDTRRKRS--IDRDQLCLYDPTYLADCLADKPRLRRVLTEGGWLCPRR
tr_Q8I7P1ComplementcomponentC3      AADGKRKRRSTDASVDPQCCILGEDLDPATCLVRAMKFSVSNISSSFHSL
tr_O97019AsC3protein_Halocynth      PEGGARKKRA-----ANPNRDFQLVAAAKVEKCRLDGQRLNLIHLTCEQR
tr_Q8WPD8ComplementcomponentC3      AAQSRKKRQIQVEQELSIEAKLHKCGEDGKKKSFSECDTCEMQRDRVIYT
tr_Q8TDJ3CD109_Homosapiens_Hum      -----------------ANLTKDYIDGVYDNAEYAERFMEENEGHIVDIH
tr_Q8IZJ3Alpha_2macroglobulinf      GLVVMTDRVSLNHRQDGGLYTDEAVPAFQPHTGSLVAVAPSRHPPRTEKR
tr_Q7Q7S6AgCP4019_Anophelesgam      --------------YEDDQTELDGFHGEGVFLKILGGFQLGNTLKVTKRT
                                                                                      

tn_CAD66666ComplementC4_Oncorh      AERVARANK------DRVCVKAFLDCCIEGEKLREKKKRDDAQSGHGRTA
tr_Q9I932ComplementC4B_Cyprinu      AKRVGKTE-------SKECVKVFQECCEFATKLRDKKRKEDQRTGHGRTV
sp_P01028_CO4_HUMANComplementC      AARVQQPD----------CREPFLSCCQFAESLR-KKSRDKGQAGLQRAL
sp_P01029_CO4_MOUSEComplementC      AARVPQQA----------CREPFLSCCKFAEDLR-RNQTRSQAHLARNNH
tr_Q9I933ComplementC4A_Cyprinu      LKRVEASKS---------CRKAFKMCCEAANERRRRETFEKRKTYLGRVA
tn_BAC82347ComplementC4_Triaki      TSRVKELD----------CRLVFQKCCDYGVELRKNQSLKVDSIAR---A
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      ATYIVDG---------EACAKAFVDCCNKIKDRK-NTETEEEEMLLARSD
tn_AAQ74974ComplementC3_Ctenop      ATYIVDG---------QECAKVFLHCCNEIKTRK-NMKTEEEEMILARSD
tr_Q9YIA7ComplementC3_S_Cyprin      SRYIADG---------KECVDAFLHCCNQMKTHK-DVKDEVEEMVLARS-
tr_Q9YIB0ComplementC3_H1_Cypri      ATYIVDG---------EECAKAFVDCCNKIKDRK-NTETEEEEMLLARSD
sp_P98093_CO3_ONCMYComplementC      AQYISDG---------DVCVQAFLVCCTEMAS-K-KIESKQDALLLSRSE
tr_Q98TS6ComplementcomponentC3      SEYISDG---------GACVTAFLHCCKEMKA-Q-RADRKEDSLLLARS-
tr_Q9PTY1ComplementcomponentC3      SEYILDG---------ASCVDAFLHCCKEMEN-L-RGEMKQDQLDLARSE
tr_Q9IBH1OrlaC3_1protein_Oryzi      SEYIMDGG--------QACVDAFVTCCKEME-KQ-QLEKKEESLQLARS-
tr_Q9IBH0OrlaC3_2protein_Oryzi      FEYILDG---------QACVDAFVTCCKEMEK-Q-QLEKKEESLQLARS-
sp_Q01833_CO3_NAJNAComplementC      AKYIQEG---------DACKAAFLECCHYIKGIR-DENQRESELFLARSD
tr_Q91132Cobravenomfactorprecu      AKYIQEG---------DACKAAFLECCRYIKGVR-DENQRESELFLARDD
tr_Q91588ComplementcomponentC3      ARYILDG---------KECVDAFVDCCKYYEKKREAEKISKDDDTLGRSD
tr_Q90633ComplementC3precursor      ATYVLDA---------KSCTEAFLSCCLYIKGIR-DEER-ELQYELARSE
sp_P01024_CO3_HUMANComplementC      TRFISLG---------EACKKVFLDCCNYITELR-RQHARASHLGLARSN
tr_Q80XP1Complementcomponent3_      ARLITQG---------ENCIKAFIDCCNHITKLR-EQHRRDHVLGLARSE
sp_P01026_CO3_RATComplementC3p      ARLITQG---------ESCLKAFMDCCNYITKLR-EQHRRDHVLGLARSD
sp_P01027_CO3_MOUSEComplementC      ARLITQG---------ENCIKAFIDCCNHITKLR-EQHRRDHVLGLARSE
sp_P12387_CO3_CAVPOComplementC      ARYVSLG---------EACVKAFLDCCTYMAQLR-QQHRREQNLGLARSD
tr_Q9GKP1ComplementcomponentC3      AQFIQHG---------DACVKAFLDCCEYIAKLR-QQHSRNKPLGLARSD
sp_Q00685_CO3_LAMJAComplementC      LKRVTGP---------KECVDAFLQCCKKAEEYR-KSESLGAKTVLRRND
sp_P98094_CO3_EPTBUComplementC      TKHIHDEG--------EGCQETFLECCKHVEEELLIAMEEEDEDLGRSQG
sp_P01031_CO5_HUMANComplementC      AARISLGP---------RCIKAFTECCVVASQLRANISHKDMQLGRLHMK
tr_Q8AYN9ComplementcomponentC5      SERLSFPPNFAMN-QKKRCAYAFMKCCVQAIKLRQ-ENVDKIILSHSATD
tr_Q969A4ComplementcomponentC3      AKLNSTSQ--------DECYFAFLTCCNHARSLR---RLGRGRGRMGGGG
tr_Q03626Alpha_1_inhibitorIIIp      MVVLSAP-------AVESELSPRGGEFEMMPLGVNKSPLPKEPPRKDPPP
tr_Q9PVU4Alpha_2_macroglobulin      LAYHRYG---------------DIVMYEYYSLSGTALELEKADSS-----
tr_O44344ComplementcomponentC3      ARVLEAECN-----LEPDQTQVYRDCCINSMNPVVTATSRSGGDGGEQNA
tr_Q8I7P1ComplementcomponentC3      DACIIEFY--------KCCYRKFEMDWRTRSGEIAIPNNVLDELPFEDEE
tr_O97019AsC3protein_Halocynth      LAIISANMQHKDENLRNSCMTAFEEACVALENDFYTQESVSRSLSANDNA
tr_Q8WPD8ComplementcomponentC3      FDDAIPG-----------CSERFYAECIALARLNSGTRRQRVQGRSIGVN
tr_Q8TDJ3CD109_Homosapiens_Hum      DFSLGSSP------------------------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      KRTFFPETWIWHC--LNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQG
tr_Q7Q7S6AgCP4019_Anophelesgam      VKDVAPP-------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      SATDIEDFFDTTNQQIRRSFPPSFAFAVVDINGK-----------GSHTV
tr_Q9I932ComplementC4B_Cyprinu      NSNEVEDFSDFGIETIRRYFPPSFEFQQIDVKEK-----------VRHKI
sp_P01028_CO4_HUMANComplementC      EILQEEDLIDEDDIPVRSFFPENWLWRVETVDRF-----------QILTL
sp_P01029_CO4_MOUSEComplementC      NMLQEEDLIDEDDILVRTSFPENWLWRVEPVDSS-----------KLLTV
tr_Q9I933ComplementC4A_Cyprinu      DDTLDEIVINEDAIYLRKYFPQSWMWTVIQTDSTG---------IIRHDA
tn_BAC82347ComplementC4_Triaki      AVEVDEEFFDETDVHVRSVFPHSWLWKTVEVLSAG---------DHKIRN
tr_Q9YIA5ComplementC3_Q2_Cypri      ---DDDYYTDSEEIVSHTQFRESWLWEEIDL------CDKCSTPATEKVI
tr_Q9YIA9ComplementC3_H1_Cypri      --DDDDYYTESEEIVSRTQFPESWLWEEIDL------CDKCPTPATEKVI
tn_AAQ74974ComplementC3_Ctenop      --DDDDYYTDSDEIVSRTQFPESWLWEEIDL------CENCPAPVKDKVL
tr_Q9YIA7ComplementC3_S_Cyprin      -DDDDDYYTESEEIVSRTQFPESWLWEEIDLCDK------CAIPTKEKAI
tr_Q9YIB0ComplementC3_H1_Cypri      --DDDDYYTESEEIVSRTQFPESWLWEEIDL------CDKCPTPATEKVI
sp_P98093_CO3_ONCMYComplementC      EDDDDDAYMRSEDIVSRSQFPESWMWEDTNLPECPAQNKHCESTSVIRNN
tr_Q98TS6ComplementcomponentC3      -EVDDNSYMDSNEIVSRTNFPESWLWSDIELPACPRQTPNCDTTSFTKHV
tr_Q9PTY1ComplementcomponentC3      ---EDDSYMDSNEISSRTKFPESWLWSDIQLPACPQQTPNCESTSFMKPV
tr_Q9IBH1OrlaC3_1protein_Oryzi      --ETDDSYMDSNEIVTRSNFPESWLWSDIILPQCPPNTPNCGSTSSVKNV
tr_Q9IBH0OrlaC3_2protein_Oryzi      --ETDDSYMDSNEIVTRSNFPESWLWSDIILPQCPQNTPNCDSTSFVKNV
sp_Q01833_CO3_NAJNAComplementC      ---FEDELFGDDNIISRSDFPESWLWLTEELTGE---PNNQGISSKTVPF
tr_Q91132Cobravenomfactorprecu      ---NEDGFIADSDIISRSDFPKSWLWLTKDLTEE---PNSQGISSKTMSF
tr_Q91588ComplementcomponentC3      ---EDDEYMLDSDIVSRTEFPESWFWKVEQMVEK---PDVNGISSKTLNV
tr_Q90633ComplementC3precursor      ---VDDAFLSDEDITSRSLFPESWLWQVEELTEP---PNEQGISMKTLPI
sp_P01024_CO3_HUMANComplementC      ---LDEDIIAEENIVSRSEFPESWLWNVEDLKE----PPKNGISTKLMNI
tr_Q80XP1Complementcomponent3_      ---LEEDIIPEEDIISRSHFPQSWLWTIEELKE----PEKNGISTKVMNI
sp_P01026_CO3_RATComplementC3p      ---VDEDIIPEEDIISRSHFPESWLWTIEELKE----PEKNGISTKVMNI
sp_P01027_CO3_MOUSEComplementC      ---LEEDIIPEEDIISRSHFPQSWLWTIEELKE----PEKNGISTKVMNI
sp_P12387_CO3_CAVPOComplementC      ---MDEDIIPEEDIISRSQFPESWLWTIEELKEP----ERNGISTKTMNI
tr_Q9GKP1ComplementcomponentC3      ---LDEEIIPEEDIISRSQFPESWLWTIEEFKE----PDKNGISTKTMNV
sp_Q00685_CO3_LAMJAComplementC      --FMELDLMNEDEVNMMAYFPQSWGWNKYKNSCKYG-------RHPQIRL
sp_P98094_CO3_EPTBUComplementC      ----EDFMIQESQVVIRSHFPESFMWEIIKLSRS------AENGKSRITK
sp_P01031_CO5_HUMANComplementC      ------TLLPVSKPEIRSYFPESWLWEVHLVPR-----------RKQLQF
tr_Q8AYN9ComplementcomponentC5      ------FLLDAMPPKIRSYFPESWLWEEHTSKSG----------SVSITK
tr_Q969A4ComplementcomponentC3      GLLDIDIDEDESQLVARTEFPETWIFEDVQVDDR---------GQAVVPV
tr_Q03626Alpha_1_inhibitorIIIp      KDP--------VIETIRNYFPETWIWDLVTVNSS---------GVTEVEM
tr_Q9PVU4Alpha_2_macroglobulin      -----------TDVTVRTVFPETWIWQLAAVGDS---------GSAQVPV
tr_O44344ComplementcomponentC3      ------------AVKVRDDFRETWFFDVVSMPEDG--------SPYLYPV
tr_Q8I7P1ComplementcomponentC3      -----ILKLTLDEAQVRTNFPETWLYEHMKADKD---------GRVSFRV
tr_O97019AsC3protein_Halocynth      N---------EFRLRKRSDFKESWISEEKKIGDD---------GTLVFRE
tr_Q8WPD8ComplementcomponentC3      -----GQVERSVASAVRKDFAEALYLDPSTLEQAG---------RRQITA
tr_Q8TDJ3CD109_Homosapiens_Hum      --------------HVRKHFPETWIWLDTNMGYR---------IYQEFEV
tr_Q8IZJ3Alpha_2macroglobulinf      LGIAEPSLLKTFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMK
tr_Q7Q7S6AgCP4019_Anophelesgam      ---------LLYHASLQRNCVKSWLWRNVTVGSS---------GTLKLAE
                                                                                      

tn_CAD66666ComplementC4_Oncorh      ALPDSITTWEIQAVSLSASHGICVAEP-----HEFRVFKKVFVSLRLPYS
tr_Q9I932ComplementC4B_Cyprinu      HLPHSITTWEIQSLSFSPSHGFCVAEP-----IDLTVFKSLFISLRLPYS
sp_P01028_CO4_HUMANComplementC      WLPDSLTTWEIHGLSLSKTKGLCVATP-----VQLRVFREFHLHLRLPMS
sp_P01029_CO4_MOUSEComplementC      WLPDSMTTWEIHGVSLSKSKGLCVAKP-----TRVRVFRKFHLHLRLPIS
tr_Q9I933ComplementC4A_Cyprinu      VAPDSITTWEIQAVGISPTKGFCIAEP-----KPLRVFQDFFLSVNLPYS
tn_BAC82347ComplementC4_Triaki      YMPDSITTWEIQAVGMFANKGFCVAEP-----KMIKVFRPFFISVKLPYS
tr_Q9YIA5ComplementC3_Q2_Cypri      YLKDSITTWQILAVSLSPTLGICVAEP-----EEMVVFKHLFIDLKMPYS
tr_Q9YIA9ComplementC3_H1_Cypri      YLKDSITTWEILAVSLSPTLGICVAEP-----EEMVVFKHLFIDLKMPYS
tn_AAQ74974ComplementC3_Ctenop      YLKDSITTWQILAVSLSPTLGICVAEP-----EEIVVFKHLFIDLKMPYS
tr_Q9YIA7ComplementC3_S_Cyprin      YLKDSITTWQILAISLSPTLGICVAEP-----EEIVVFKSLFIDLKMPYS
tr_Q9YIB0ComplementC3_H1_Cypri      YLKDSITTWEILAVSLSPTLGICVAEP-----EEMVVFKHLFIDLKMPYS
sp_P98093_CO3_ONCMYComplementC      FLKDSITTWQITAISLSKTHGICVADP-----FEMIVLKEFFIDLKLPYS
tr_Q98TS6ComplementcomponentC3      PLQDSITTWQFTGISLSKTHGICVGDP-----LEVIVFKEFFVDLKLPYS
tr_Q9PTY1ComplementcomponentC3      PLQDSITTWQFTGISLSRTHGICVGEP-----LEVIVRKDFFIDLRLPYS
tr_Q9IBH1OrlaC3_1protein_Oryzi      PLQDSITTWEFTGISLSRTHGICVGES-----LEVIVRKDFFIDLRLPYS
tr_Q9IBH0OrlaC3_2protein_Oryzi      PLPDSITTWEFTGISLSRTHGICVGES-----LEVIVRKDFFIDLRLPYS
sp_Q01833_CO3_NAJNAComplementC      YLRDSITTWELLAVGLSPTKGICVAEP-----YEITVMKDFFIDLRLPYS
tr_Q91132Cobravenomfactorprecu      YLRDSITTWVVLAVSFTPTKGICVAEP-----YEIRVMKVFFIDLQMPYS
tr_Q91588ComplementcomponentC3      FLKDSITTWEVLAVSLSENKGLCVGQP-----YEIKVMKDFFIDLKLPYS
tr_Q90633ComplementC3precursor      YLKDSITTWEVLAVSISENKGLCVADP-----YEITVMKEFFIDLRLPYS
sp_P01024_CO3_HUMANComplementC      FLKDSITTWEILAVSMSDKKGICVADP-----FEVTVMQDFFIDLRLPYS
tr_Q80XP1Complementcomponent3_      FLKDSITTWEILAVSLSDKKGICVADP-----YEIRVMQDFFIDLRLPYS
sp_P01026_CO3_RATComplementC3p      FLKDSITTWEILAVSLSDKKGICVADP-----YEITVMQDFFIDLRLPYS
sp_P01027_CO3_MOUSEComplementC      FLKDSITTWEILAVSLSDKKGICVADP-----YEIRVMQDFFIDLRLPYS
sp_P12387_CO3_CAVPOComplementC      FLKDSITTWEILAVSLSDKKGICVADP-----FEVTVMQDFFIDLRLPYS
tr_Q9GKP1ComplementcomponentC3      FLKDSITTWEILAVSLSDKKGICVADP-----YEVVVKQDFFIDLRLPYS
sp_Q00685_CO3_LAMJAComplementC      QLPDTITTWNMQAVSISKTRGVCLADP-----LLLVSTKDFFIKLHLPYS
sp_P98094_CO3_EPTBUComplementC      KMPDSITTWDIQAVEVSQSKGLCVGPS-----LELTVFKQFFLKVHTPYA
sp_P01031_CO5_HUMANComplementC      ALPDSLTTWEIQGIGISN-TGICVADT-----VKAKVFKDVFLEMNIPYS
tr_Q8AYN9ComplementcomponentC5      IIPDSLTIWELKAVGVFS-EGICVSE------EKIQVSQDISVDVPLPYS
tr_Q969A4ComplementcomponentC3      TVPGSITTWVIQAVGISTANGMCVAKP-----FRMKSFKKFFIHLQLPYS
tr_Q03626Alpha_1_inhibitorIIIp      TVPDTITEWKAGALCLSNDTGLGLSSV-----ATLQAFQPFFVELTMPYS
tr_Q9PVU4Alpha_2_macroglobulin      TVPDTITSWDTEAFCLS-SKGLGLAPP-----AKLTVFQPFFLELSLPYS
tr_O44344ComplementcomponentC3      SIPSSITDWHLTAVSLSPTQGMCVEDE-----TTVSVFQDFFIQLHLPYS
tr_Q8I7P1ComplementcomponentC3      TVPDTITTWIMQAIAVSNTTGFGLTPP-----FNLKAFKSFFVSLKLPYS
tr_O97019AsC3protein_Halocynth      NAPDSITIYEIAAFGMSTVSSFCIAKP-----KEVKVHKNVFIQLYLPYS
tr_Q8WPD8ComplementcomponentC3      KARDSITTYEIDAMASADTPDGFCIAPT----TNVKVFKNVFVQVYTPYS
tr_Q8TDJ3CD109_Homosapiens_Hum      TVPDSITSWVATGFVISEDLGLGLTTTP----VELQAFQPFFIFLNLPYS
tr_Q8IZJ3Alpha_2macroglobulinf      LSVPKGIQFVGHPGKRHVTKKMCVAPGEAEPIWVVLSFSDLGLNNITAKA
tr_Q7Q7S6AgCP4019_Anophelesgam      VFPESITSWTLTGFSIDPSYGLSIIRKP----IELTTIQPFLIVDYLPYS
                                        .   :                               . :    . :

tn_CAD66666ComplementC4_Oncorh      VKRFEQMSIAPVVYNYCDEA-------AQIALHMEGNDKLCSPGSSSIKT
tr_Q9I932ComplementC4B_Cyprinu      VKRFEQLSIVAVIFNYGKME-------RELVVQMQKVDGLCSPGSASSSS
sp_P01028_CO4_HUMANComplementC      VRRFEQLELRPVLYNYLDKN-------LTVSVHVSPVEGLCLAGGGG--L
sp_P01029_CO4_MOUSEComplementC      IRRFEQFELRPVLYNYLNDD-------VAVSVHVTPVEGLCLAGGGM--M
tr_Q9I933ComplementC4A_Cyprinu      VKRNEQLQVKAVVYNYKEES-------LKIIVKMDKKEGLCTAGGS--DL
tn_BAC82347ComplementC4_Triaki      VKRNEQLDLTVILYNYLHED-------LEVAVYMRKAEGLRTAAGSR-EK
tr_Q9YIA5ComplementC3_Q2_Cypri      AVRGEQLEIKAIIHNYTPNK-------QKVRVEFMETEDVCSFASKKGKY
tr_Q9YIA9ComplementC3_H1_Cypri      AVRGEQLEIRAIIHNYTPNK-------QKVRVEFMETEDVCSFASKKGKY
tn_AAQ74974ComplementC3_Ctenop      AVRGEQLEIKAIIHNYTPKK-------QKVRVEFMEAPDVCSFASKKGKH
tr_Q9YIA7ComplementC3_S_Cyprin      AVRGEQLEIRAIIHNYTPKK-------QKVRVEFMETEDVCSSASKKGKY
tr_Q9YIB0ComplementC3_H1_Cypri      AVRGEQLEIRAIIHNYTPNK-------QKVRVEFMETEDVCSFASKKGKY
sp_P98093_CO3_ONCMYComplementC      AVRNEQLEVKAILHNYSEDP-------IIVRVELMENGEVCSSASKKGKY
tr_Q98TS6ComplementcomponentC3      AVRGEQVEVKAILHNYSEDP-------ATVRVDLLEEEHVCSAASKRGKY
tr_Q9PTY1ComplementcomponentC3      AVRGEQLEIKAILHNYSPDV-------ITVRVDLIEEENVCSVASKHTRY
tr_Q9IBH1OrlaC3_1protein_Oryzi      AVRGEQLEVKAILHNYRPEL-------ITVRIDLAEEKDTCSAASKRGKY
tr_Q9IBH0OrlaC3_2protein_Oryzi      AVRGEQLEVKAILHNYRPEL-------ITVRIDLLEEKDTCSAASKRGKY
sp_Q01833_CO3_NAJNAComplementC      VVKNEQVEIRAILYNY-ADED------IYVRVELIYNPAFCSASTEGQRY
tr_Q91132Cobravenomfactorprecu      VVKNEQVEIRAILHNY-VNED------IYVRVELLYNPAFCSASTKGQRY
tr_Q91588ComplementcomponentC3      VVRNEQVEIRAILYNY-RNDR------IKVRVELIHNPEFCSLSTAKKKY
tr_Q90633ComplementC3precursor      AVRNEQVEVRAILYNYWTNK-------IKVRVELMYNPALCSASTTKTRY
sp_P01024_CO3_HUMANComplementC      VVRNEQVEIRAVLYNYRQNQE------LKVRVELLHNPAFCSLATTKRRH
tr_Q80XP1Complementcomponent3_      VVRNEQVEIRAVLFNYREQEE------LKVRVELLHNPAFCSMATAKNRY
sp_P01026_CO3_RATComplementC3p      VVRNEQVEIRAVLFNYREQEK------LKVRVELLHNPAFCSMATAKKRY
sp_P01027_CO3_MOUSEComplementC      VVRNEQVEIRAVLFNYREQEE------LKVRVELLHNPAFCSMATAKNRY
sp_P12387_CO3_CAVPOComplementC      VVRNEQVEIRAVLYNYREAQS------LKVRVELLHNPAFCSLATAKKRH
tr_Q9GKP1ComplementcomponentC3      VVRNEQVEIRAILYNYREAED------LKVRVELLYNPAFCSLATAKKRH
sp_Q00685_CO3_LAMJAComplementC      VKRGEQTEIRVILYNYMEES-------LTILTEMDIVESICSTSKSGAKP
sp_P98094_CO3_EPTBUComplementC      LKQYEQVELRVVIYNYMNQD-------VKGEIQVKCGDGICTDAEQNEPL
sp_P01031_CO5_HUMANComplementC      VVRGEQIQLKGTVYNYRTSG-------MQFCVKMSAVEGICTSESPVIDH
tr_Q8AYN9ComplementcomponentC5      MVRGEQIELRGSVYNQHLSK-------TEFRVTLTATDGVCVFRGAQQGK
tr_Q969A4ComplementcomponentC3      IIRGEQVAIRATIFNYDQQD-------LRVNVYMQGVEGVCSGARAGERS
tr_Q03626Alpha_1_inhibitorIIIp      VIRGEAFMLKATVMNYLPTS-------LPMAVQLEASPDFTAVPVGNDQD
tr_Q9PVU4Alpha_2_macroglobulin      IIRGEIFELKATVFNYLSKC-------IMVKVTPAPSTDYTLKASSDDQY
tr_O44344ComplementcomponentC3      VVRLEQTQVIATIFNYGFSD-------FEVSVNFTVDQGLCTAENPAIRH
tr_Q8I7P1ComplementcomponentC3      AQRGEQVSVIATVFNYKDQAE-----MVRIYLFKKPNDDFCTYSNYGSGS
tr_O97019AsC3protein_Halocynth      VRVREQAVIRFAVFNYGPQE-------IEVTVKVLHSKEICTNFISDDFR
tr_Q8WPD8ComplementcomponentC3      LKKREQALIKLSVFNYGDTLVT-------VDIMMRAHPVLCTHFRTDGSY
tr_Q8TDJ3CD109_Homosapiens_Hum      VIRGEEFALEITIFNYLKDAT-------EVKVIIEKSDKFDILMTSNEIN
tr_Q8IZJ3Alpha_2macroglobulinf      LAYGDTNCCRDGRSSKHPEENHADRR-VPIGVDHVRRSVMVEAEGVPRAY
tr_Q7Q7S6AgCP4019_Anophelesgam      IKREKEVLLQIALFNNFEQDHT-----VDVTLYNMKNEMEILGRPVTNQS
                                        .         .                                   

tn_CAD66666ComplementC4_Oncorh      YV--------NITVEAHSSKAVTFSAVPMETGPIPIKIRLYDIENE--D-
tr_Q9I932ComplementC4B_Cyprinu      AV--------QISLEPQSSQTVTFPAVPMKIGEIPISIELYEVEEE--EK
sp_P01028_CO4_HUMANComplementC      AQ--------QVLVPAGSARPVAFSVVPTAAAAVSLKVVARGS--F--EF
sp_P01029_CO4_MOUSEComplementC      AQ--------QVTVPAGSARPVAFSVVPTAAANVPLKVVARG------VF
tr_Q9I933ComplementC4A_Cyprinu      KE--------EVVVPGNSAVAVYFTVVPLVIGNIPINVLAYAS------D
tn_BAC82347ComplementC4_Triaki      SR--------NVLVKANSAASVQFTTVPLVVGNMPINVIAFSRT-----H
tr_Q9YIA5ComplementC3_Q2_Cypri      R--------TTVSVEKDSSISVSYVIIPMTLGNHMIEVKASAYD-----A
tr_Q9YIA9ComplementC3_H1_Cypri      R--------TTVSVEKDSSISVSYVIIPMTLGNHMIEVKASAYD-----A
tn_AAQ74974ComplementC3_Ctenop      R--------TTISVDKDSSIAVSYVIIPMTLGNHMIEVKAAAFD-----S
tr_Q9YIA7ComplementC3_S_Cyprin      R--------TTVSVDKGSSISVSYVIIPMTLGNHMIEVKASAYD-----S
tr_Q9YIB0ComplementC3_H1_Cypri      R--------TTVSVEKDSSISVSYVIIPMTLGNHMIEVKASAYD-----A
sp_P98093_CO3_ONCMYComplementC      R--------QEVNMDPMSTRVVPYVIIPMKLGLHSIEVKASVKN-----S
tr_Q98TS6ComplementcomponentC3      R--------QEVTVGPHTTRAVPFVIIPMKKGQYSIEVKAAVKD-----S
tr_Q9PTY1ComplementcomponentC3      R--------QEVKVGQQTTRSVPFVIIPMKEGQFNIEVKAAVKD-----S
tr_Q9IBH1OrlaC3_1protein_Oryzi      R--------QEVNVGAMSTRSVPFIIIPMKEGTLPIEVKAAVKD-----S
tr_Q9IBH0OrlaC3_2protein_Oryzi      R--------QELNVGKMSTRSVPFIIIPMKEGTLPIEVKAAVKD-----S
sp_Q01833_CO3_NAJNAComplementC      R--------QQFPIKALSSRAVPFVIVPLEQGLHDVEVIASVR-----GE
tr_Q91132Cobravenomfactorprecu      R--------QQFPIKALSSRAVPFVIVPLEQGLHDVEIKASVQ-----EA
tr_Q91588ComplementcomponentC3      R--------QEVWIGALSSIAVPIVIVPLTLGQHDIEVKASVSAQS--GF
tr_Q90633ComplementC3precursor      Q--------QIFQLEPQSSDAVPFVIVPLELGQHDVEVKAAVWN-----S
sp_P01024_CO3_HUMANComplementC      Q--------QTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYH-----H
tr_Q80XP1Complementcomponent3_      F--------QTIKIPPKSSVAVPYVIVPLKIGQQEVEVKAAVFN-----H
sp_P01026_CO3_RATComplementC3p      Y--------QTIEIPPKSSVAVPYVIVPLKIGLQEVEVKAAVFN-----H
sp_P01027_CO3_MOUSEComplementC      F--------QTIKIPPKSSVAVPYVIVPLKIGQQEVEVKAAVFN-----H
sp_P12387_CO3_CAVPOComplementC      T--------QTVTIGPKSSVAVPYVLVPLKIGLQEVEVKAAVYN-----Y
tr_Q9GKP1ComplementcomponentC3      Q--------QTLTVPAKSSVPVPYIIVPLKTGLQEVEVKAAVY-----NH
sp_Q00685_CO3_LAMJAComplementC      S--------QKSTVKGKGAMVVSFPIVPLKIGEHHISIRSRVYG-----R
sp_P98094_CO3_EPTBUComplementC      K--------SRFAVEKNSATSFSFMVVPLSSSDSSVSVLARVFG-----S
sp_P01031_CO5_HUMANComplementC      QGTKSSK-CVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFG-----
tr_Q8AYN9ComplementcomponentC5      DGKPHE---NKGKIGGRSVALVTFYIMALEAGTHTLTFTLTTKWG-----
tr_Q969A4ComplementcomponentC3      ER-------KTLFIKGNDAASVLFPIIPLEVGTFPIRVVAFSTAAG----
tr_Q03626Alpha_1_inhibitorIIIp      S----------YCLGANGRHTSSWLVTPKSLGNVNFSVSVEAQQ------
tr_Q9PVU4Alpha_2_macroglobulin      S----------SCLCANGRKTFKWILTPSVLGVLNITVSAEAES------
tr_O44344ComplementcomponentC3      VF-----------VESKRAASTTFHCTPCGSRGIPYTVTAGGSK------
tr_Q8I7P1ComplementcomponentC3      S-------LYEVLVDAHGATSVSFPIVPTELGDIPIQVKIISRN------
tr_O97019AsC3protein_Halocynth      KL-------VVLTIPSRRSATSYFTILPVKIPKGGKSKIELKAEGD--SS
tr_Q8WPD8ComplementcomponentC3      DLVR------TISVGPNSAGSASFAVLPLRIPAGDIPKATVEVYITDNRN
tr_Q8TDJ3CD109_Homosapiens_Hum      ATG----HQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT------
tr_Q8IZJ3Alpha_2macroglobulinf      TYSAFFCPSERVHISTPNKYEFQYVQRPLRLTRFDVAVRAHNDARV-ALS
tr_Q7Q7S6AgCP4019_Anophelesgam      YT-------KTVSVPPKVLFPVSFLVKAQKLGEMAVHVTASIAN-----G
                                                 :             .                      

tn_CAD66666ComplementC4_Oncorh      -GSDAIEKILNVRTEGIEKRVEETHFVDLNANIGKSRQSFTFDGKLPD--
tr_Q9I932ComplementC4B_Cyprinu      LRVDAIQKMLLVKNEGVEIREELTFFINLDG---RSDRRFFINGFFPN--
sp_P01028_CO4_HUMANComplementC      PVGDAVSKVLQIEKEGAIHREELVYELNPLD---HRGRTLEIPGNSDP--
sp_P01029_CO4_MOUSEComplementC      DLGDAVSKILQIEKEGAIHREELVYNLDPLN---NLGRTLEIPGSSDP--
tr_Q9I933ComplementC4A_Cyprinu      TVNDRVEKELRVEGEGEIATIDREYNIDPKLR------KLDIDIPVPA--
tn_BAC82347ComplementC4_Triaki      TYSDAVLKHLKVLSEGVIVTEESSIPINPKAK-----ASYEIYEEEPS--
tr_Q9YIA5ComplementC3_Q2_Cypri      IYTDGVRKQLKVVSEGVLTSVHKGNVELNPVK---NGDKPLVFK---SVI
tr_Q9YIA9ComplementC3_H1_Cypri      IYTDGVRKPLKVVSEGVLIPLHRKNVELNPVK---NGEKPIVLK---SDI
tn_AAQ74974ComplementC3_Ctenop      VYTDGVRKSLKVVSEGVLVQRQTQNVELNPVK---NGEKTIVVK---SDT
tr_Q9YIA7ComplementC3_S_Cyprin      IYTDGVRKPLKVVAEGVLVPLQRQNLELNPAK---NGEKPILLK---GEI
tr_Q9YIB0ComplementC3_H1_Cypri      IYTDGVRKPLKVVSEGVLIPLHRKNVELNPVK---TGEKPIVLK---SDI
sp_P98093_CO3_ONCMYComplementC      GSNDGVKRDLRVVAEGVLVKKET-NVLLNPVKH--GGEQTSHIP---SGV
tr_Q98TS6ComplementcomponentC3      SLHDGIRKTLHVVPEGVLVQSPQ-IIVLDPSTQGVAGKQEQTLV---SGI
tr_Q9PTY1ComplementcomponentC3      SLNDGIVKVLRVVPEGVLIKQPQ-IITLDPSKT--GGEQVEILN---SRI
tr_Q9IBH1OrlaC3_1protein_Oryzi      YLSDGVKKDLRVVPPGVLVKAIE-STILDPAHKGKNGEQVEVLN---SNI
tr_Q9IBH0OrlaC3_2protein_Oryzi      YLSDGVKKDLRVVPPGVLVKTAK-TVTLDPAHKGKNGEQVEVLN---SNI
sp_Q01833_CO3_NAJNAComplementC      LASDGVRKKLKVVPEGERK-NIVTIIELDPSVKGVGGTQELTVI---ANK
tr_Q91132Cobravenomfactorprecu      LWSDGVRKKLKVVPEGVQK-SIVTIVKLDPRAKGVGGTQLEVIK---ARK
tr_Q91588ComplementcomponentC3      FGADGVRKKLKVVPEGMRIAQDVKTVILEPEVKGKDGVQEEKVE---ALN
tr_Q90633ComplementC3precursor      FVSDGVKKKLRVVPEGMRLEKTVKIVELDPKTLGNNGVQEVKVK---AAN
sp_P01024_CO3_HUMANComplementC      FISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIP---PAD
tr_Q80XP1Complementcomponent3_      FISDGVKKTLKVVPEGMRINKTVAIHTLDPEKLGQGGVQKVDVP---AAD
sp_P01026_CO3_RATComplementC3p      FISDGVKKILKVVPEGMRVNKTVAVRTLDPEHLNQGGVQREDVN---AAD
sp_P01027_CO3_MOUSEComplementC      FISDGVKKTLKVVPEGMRINKTVAIHTLDPEKLGQGGVQKVDVP---AAD
sp_P12387_CO3_CAVPOComplementC      FISDGVKKTLKVVPEGMRVNKTVAIRTLNPEQLGQGGVQREEIP---AAD
tr_Q9GKP1ComplementcomponentC3      FISDGVKKTLKVVPEGMRVNKTVVTRTLDPEHKGQQGVQREEIP---PAD
sp_Q00685_CO3_LAMJAComplementC      TFGDGVQKILRVAPEGVRDIRSESRSVHVEER------ETFFIK---NEI
sp_P98094_CO3_EPTBUComplementC      DVHDAVEKDLRVMPEGNYEEMSRSWSVQPRRHG---GQQVIVVD---NET
sp_P01031_CO5_HUMANComplementC      --KEILVKTLRVVPEGVKRESYSG-VTLDPRGIYGTISRRKEFP---YRI
tr_Q8AYN9ComplementcomponentC5      --TESVVKKLKVVPEGIRKEIQIG-GRIDPNGVFGTSMRKLEFK---NVI
tr_Q969A4ComplementcomponentC3      --GDIIEKSLQVIPEGVERRLVRSIFVDPKGRARDRKREGEEEVALPTEH
tr_Q03626Alpha_1_inhibitorIIIp      -SPELCGSQVATVPETGRKDTVVKVLIVEPEGIKKEHTFSSLLCASDAEL
tr_Q9PVU4Alpha_2_macroglobulin      -SQTVCDNEIVSVPERGRIDTVTRSLLVQAEGTEKTETYSWLLCPKGDTL
tr_O44344ComplementcomponentC3      -KRDSVRNNLRVVSQGVMQRKSRSLTLNPGRVMFSDDVTTPSPNNSLGSG
tr_Q8I7P1ComplementcomponentC3      FDNDGEQRILKVVPEGIERRETHSVVLDPLDVLRDPSDAKPSAAPTTPSK
tr_O97019AsC3protein_Halocynth      ENSDWIEKMLLVEPPGQHNDSHGTFLLSPDVNGGVIDFEIDLATKNVLAG
tr_Q8WPD8ComplementcomponentC3      RTYDSVKKEILIEDEGELKDIYETFPIDLKNSRVQQTQINFTFPEQFVLG
tr_Q8TDJ3CD109_Homosapiens_Hum      -ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLS--------
tr_Q8IZJ3Alpha_2macroglobulinf      SGPQDTAGMIEIVLGGHQNTRSWISTSKMGEPVASAHTAKILSWDEFRTF
tr_Q7Q7S6AgCP4019_Anophelesgam      LETDALEKVIRVMPESLVQPRMDRRFFCFDEYKNQTFLIYLDIIKKADNG
                                             :                                        

tn_CAD66666ComplementC4_Oncorh      ---NTVPGSST---------------------------------------
tr_Q9I932ComplementC4B_Cyprinu      ---NTVPETDV---------------------------------------
sp_P01028_CO4_HUMANComplementC      ---NMIPDGDF---------------------------------------
sp_P01029_CO4_MOUSEComplementC      ---NIVPDGDF---------------------------------------
tr_Q9I933ComplementC4A_Cyprinu      ---DEIPGGVDS--------------------------------------
tn_BAC82347ComplementC4_Triaki      ---NLVPFTDN---------------------------------------
tr_Q9YIA5ComplementC3_Q2_Cypri      P-ADRLPDTP----------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      P-VDRVPDTP----------------------------------------
tn_AAQ74974ComplementC3_Ctenop      P-ADRVPDTP----------------------------------------
tr_Q9YIA7ComplementC3_S_Cyprin      PA-DRVPDTP----------------------------------------
tr_Q9YIB0ComplementC3_H1_Cypri      P-VDRVPGTP----------------------------------------
sp_P98093_CO3_ONCMYComplementC      PR-NQVPNSD----------------------------------------
tr_Q98TS6ComplementcomponentC3      PKKDLVQDTP----------------------------------------
tr_Q9PTY1ComplementcomponentC3      PRKDMVPNTP----------------------------------------
tr_Q9IBH1OrlaC3_1protein_Oryzi      PKSNFIPSSP----------------------------------------
tr_Q9IBH0OrlaC3_2protein_Oryzi      PESNMIPNSP----------------------------------------
sp_Q01833_CO3_NAJNAComplementC      L-DDKVPDTE----------------------------------------
tr_Q91132Cobravenomfactorprecu      L-DDRVPDTE----------------------------------------
tr_Q91588ComplementcomponentC3      P-KNVVPRTD----------------------------------------
tr_Q90633ComplementC3precursor      L-SDIVPNTE----------------------------------------
sp_P01024_CO3_HUMANComplementC      L-SDQVPDTE----------------------------------------
tr_Q80XP1Complementcomponent3_      L-SDQVPDTD----------------------------------------
sp_P01026_CO3_RATComplementC3p      L-SDQVPDTD----------------------------------------
sp_P01027_CO3_MOUSEComplementC      L-SDQVPDTD----------------------------------------
sp_P12387_CO3_CAVPOComplementC      L-SDQVPDTD----------------------------------------
tr_Q9GKP1ComplementcomponentC3      L-SDQVPDTE----------------------------------------
sp_Q00685_CO3_LAMJAComplementC      S-PDVVPNSD----------------------------------------
sp_P98094_CO3_EPTBUComplementC      P-QNVVPGTE----------------------------------------
sp_P01031_CO5_HUMANComplementC      P-LDLVPKTE----------------------------------------
tr_Q8AYN9ComplementcomponentC5      P-PNIVPKST----------------------------------------
tr_Q969A4ComplementcomponentC3      DVDPDNG--LQF--------------------------------------
tr_Q03626Alpha_1_inhibitorIIIp      SETLSL--------------------------------------------
tr_Q9PVU4Alpha_2_macroglobulin      SEEVDL--------------------------------------------
tr_O44344ComplementcomponentC3      PGTIFGEG-FQH--------------------------------------
tr_Q8I7P1ComplementcomponentC3      IQSSPKGNGEQN--------------------------------------
tr_O97019AsC3protein_Halocynth      TIKCNLYFYG----------------------------------------
tr_Q8WPD8ComplementcomponentC3      TRKCMLY-------------------------------------------
tr_Q8TDJ3CD109_Homosapiens_Hum      --------------------------------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      WISWRGGLIQVGHGPEPSNESVIVAWTLPRPPEVQFIGFSTGWGSMGEFR
tr_Q7Q7S6AgCP4019_Anophelesgam      SIKIEFR-------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      -----------------NIFVKMEG-ELFGKSTSKTLLSPDGVS------
tr_Q9I932ComplementC4B_Cyprinu      -----------------NLFVKLEE-EAFAKSTAVPLLSSSKVE------
sp_P01028_CO4_HUMANComplementC      -----------------NSYVRVTASDPLDTLGSEGALSPGGVA------
sp_P01029_CO4_MOUSEComplementC      -----------------SSLVRVTASEPLETMGSEGALSPGGVA------
tr_Q9I933ComplementC4A_Cyprinu      -----------------EISLSLKG--GVMGESVNNCLNLEGIN------
tn_BAC82347ComplementC4_Triaki      -----------------YLYIRAIG--RITGEAVENSLTAAGIE------
tr_Q9YIA5ComplementC3_Q2_Cypri      -----------------ADMYIAITG-EEITQTVEQAISGSFMG------
tr_Q9YIA9ComplementC3_H1_Cypri      -----------------ANTYISITG-EEIAQTVEQAISGDFMG------
tn_AAQ74974ComplementC3_Ctenop      -----------------ANTFITIVG-EEISQTVEQAISGDFMG------
tr_Q9YIA7ComplementC3_S_Cyprin      -----------------ANTYISITG-EEISQTVEQAISGDFMG------
tr_Q9YIB0ComplementC3_H1_Cypri      -----------------ANTYISITG-EEIAQTVEQAISGDFMG------
sp_P98093_CO3_ONCMYComplementC      -----------------ADTLISVTAGEQTSVLVEQAISGDSLG------
tr_Q98TS6ComplementcomponentC3      -----------------TSIQISVTGREQVSALVENAISGTSLG------
tr_Q9PTY1ComplementcomponentC3      -----------------TTTQISVTGRENVGQLVENAISGQSMG------
tr_Q9IBH1OrlaC3_1protein_Oryzi      -----------------TSTQISLTGREQVSGLVENAISGKSMG------
tr_Q9IBH0OrlaC3_2protein_Oryzi      -----------------TSTQISVTGREQVSSLVENAISGKSLG------
sp_Q01833_CO3_NAJNAComplementC      -----------------VETRISVLG-DPVAQIIENSIDGSKLN------
tr_Q91132Cobravenomfactorprecu      -----------------IETKIIIQG-DPVAQIIENSIDGSKLN------
tr_Q91588ComplementcomponentC3      -----------------IDTTITLQG-TPISQMVEDAIDGNNMN------
tr_Q90633ComplementC3precursor      -----------------SETKVSIQG-NPVSILVEKATDGTKLK------
sp_P01024_CO3_HUMANComplementC      -----------------SETRILLQG-TPVAQMTEDAVDAERLK------
tr_Q80XP1Complementcomponent3_      -----------------SETRIILQG-SPVVQMAEDAVDGERLK------
sp_P01026_CO3_RATComplementC3p      -----------------SETRILLQG-TPVAQMAEDAVDGERLK------
sp_P01027_CO3_MOUSEComplementC      -----------------SETRIILQG-SPVVQMAEDAVDGERLK------
sp_P12387_CO3_CAVPOComplementC      -----------------SETKILLQG-TPVAQMAEDAVDAERLK------
tr_Q9GKP1ComplementcomponentC3      -----------------SETKILLQG-TPVAQMVEDAIDGDRLK------
sp_Q00685_CO3_LAMJAComplementC      -----------------VLTFISVKG-DELAETMVNCLDAKSIS------
sp_P98094_CO3_EPTBUComplementC      -----------------MSAFLSAQG-NLVAETIQNTLKGSKIS------
sp_P01031_CO5_HUMANComplementC      -----------------IKRILSVKG-LLVGEILSAVLSQEGIN------
tr_Q8AYN9ComplementcomponentC5      -----------------VDRILTVNG-EVLGALLSIINNPEGLK------
tr_Q969A4ComplementcomponentC3      ------------DVVDVRLPPETIEGSEQCAVSIMGDIMGPTITTTIGG-
tr_Q03626Alpha_1_inhibitorIIIp      -----------------LLPPTVVKDSARAHFSVMGDILSSAIKNTQ---
tr_Q9PVU4Alpha_2_macroglobulin      -----------------TLPKDVIEGSARSSVSVIGDILGRALTNLH---
tr_O44344ComplementcomponentC3      ------------EEIAISLPGSSIPDTESCSVKLIGNLLGTASTDPIGG-
tr_Q8I7P1ComplementcomponentC3      ------------NRLSLKLPKSAIPESEYAMLTVIGTLIGPSVSNIIGGR
tr_O97019AsC3protein_Halocynth      ---------------------------HIMGPNIEVELEGRLAN------
tr_Q8WPD8ComplementcomponentC3      -------------------AYMDFMGPAIEVDPVTQEANNVN--------
tr_Q8TDJ3CD109_Homosapiens_Hum      ----------------FSFPPNTVTGSERVQITAIGDVLGPSING-----
tr_Q8IZJ3Alpha_2macroglobulinf      IWRKMEVDESYSEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLN---
tr_Q7Q7S6AgCP4019_Anophelesgam      -----------------------------LNPNLLTMVIKN---------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      ---SLLNAPHGCAEQTMKRMGPTALALRYLDLSQRWYELP---PGIRDTA
tr_Q9I932ComplementC4B_Cyprinu      ---NLIRAPKGCGEQTMIFMSPTALSIRYLDKSQRWLELE---AGSRDKA
sp_P01028_CO4_HUMANComplementC      ---SLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLP---PETKDHA
sp_P01029_CO4_MOUSEComplementC      ---SLLRLPQGCAEQTMIYLAPTLTASNYLDRTEQWSKLS---PETKDHA
tr_Q9I933ComplementC4A_Cyprinu      ---KLINLPTGCAEQTMVKMSPAIHAMRYLDATNQWISLK---AERRDEA
tn_BAC82347ComplementC4_Triaki      ---KLIRVPTGCAEQTAMHMAPTVFAVEYLDQSDQWISLK---AERKDEA
tr_Q9YIA5ComplementC3_Q2_Cypri      ---RLIVQPSGSGEQNMMLMTLPLIATHYLDSTSQWDTVG---MERRNEA
tr_Q9YIA9ComplementC3_H1_Cypri      ---RLIIQPNGCGEQIMIGMTLPVIATHYLDSTSQWETVG---MERRNEA
tn_AAQ74974ComplementC3_Ctenop      ---RLIVQPHGCGEQNMIFMTLPLIATHYLDSTNQWEAVG---MERRSEA
tr_Q9YIA7ComplementC3_S_Cyprin      ---RLIVQPSGCGEQNMIGMTLPVIATHYLDNTNQWEAVG---IQRRTEA
tr_Q9YIB0ComplementC3_H1_Cypri      ---RLIIQPNGCGEQIMIGMTLPVIATHYLDSTNQWETVG---MERRNEA
sp_P98093_CO3_ONCMYComplementC      ---SLIVQPVGCGEQNMIYMTLPVIATHYLDNTKKWEDIG---LDKRNTA
tr_Q98TS6ComplementcomponentC3      ---SLIKQPYGCGEQNMITMTLPVIAAIYLDKTNQWETVG---FEKRKEA
tr_Q9PTY1ComplementcomponentC3      ---TLIYQPSGCGEQNMIHMTLPVIAATYLDKTNQWETVG---FQKRNEA
tr_Q9IBH1OrlaC3_1protein_Oryzi      ---TLIYQPSGCGEQNMIHMTLPVIATIYLDKTNQWEAVG---FQKRAEA
tr_Q9IBH0OrlaC3_2protein_Oryzi      ---TLIKQPSGCGEQNMMRMTLPVIATTYLDKTNQWEAVG---FQKRDEA
sp_Q01833_CO3_NAJNAComplementC      ---HLIITPSGCGEQNMITMTPSVIATYYLDATGQWENLG---VDRRTEA
tr_Q91132Cobravenomfactorprecu      ---HLIITPSGCGEQNMIRMAAPVIATYYLDTTEQWETLG---INRRTEA
tr_Q91588ComplementcomponentC3      ---HLIVVPAGCGEQNMISTTPSVIATRYLDASGQWERVG---VNRRDQA
tr_Q90633ComplementC3precursor      ---HLIVTPSGCGEQNMIGMTPTVIAVHYLDSTMQWETFG---INRRTEA
sp_P01024_CO3_HUMANComplementC      ---HLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFG---LEKRQGA
tr_Q80XP1Complementcomponent3_      ---HLIVTPAGCGEQNMIGMTPTVIAVHYLDQTEQWEKFG---IEKRQEA
sp_P01026_CO3_RATComplementC3p      ---HLIVTPSGCGEQNMIGMTPTVIAVHYLDQTEQWEKFG---LEKRQEA
sp_P01027_CO3_MOUSEComplementC      ---HLIVTPAGCGEQNMIGMTPTVIAVHYLDQTEQWEKFG---IEKRQEA
sp_P12387_CO3_CAVPOComplementC      ---HLIITPSGCGEQNMIGMTPTVIAVHYLDQTEQWEKFG---LEKRQEA
tr_Q9GKP1ComplementcomponentC3      ---HLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFG---LEKRQEA
sp_Q00685_CO3_LAMJAComplementC      ---NLIQIPTGCGEQNMIKMAPTTLTLIYLDSVQEWEKIG---LHRREEA
sp_P98094_CO3_EPTBUComplementC      ---NLLRLPRGCGEQNMMYTSITVMVARYLNRSDQWNKMGD--PQLKKRS
sp_P01031_CO5_HUMANComplementC      ---ILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKL
tr_Q8AYN9ComplementcomponentC5      ---QLTNLPRGNAEMELMGLLPIYYVYNYLEKTEKWGILGKEAAASEKEL
tr_Q969A4ComplementcomponentC3      -LGTLLRLPTGCGEQTMIKLAPNVYVLSYLHCTDQITKDV------EEKA
tr_Q03626Alpha_1_inhibitorIIIp      ---NLIQMPYGCGEQNMVLFAPNIYVLKYLNETQQLTEKIK------SKA
tr_Q9PVU4Alpha_2_macroglobulin      ---GLLQMPYGCGEQNMAILSPNIYILQYLENTEQLTSAIR------ERA
tr_O44344ComplementcomponentC3      -LDHLVRQPRGCGEQTMIYLAPTLFVYQYLIAVGSDTAEQ------EARI
tr_Q8I7P1ComplementcomponentC3      GLDSIIKMPTGCGEQTMLKLAPNVFVFNYLRSTKQVTQQI------EATA
tr_O97019AsC3protein_Halocynth      -LQNLINSPGGCGEQNMIRIAPVVYIHAYRSNLEAFTVTD----AQRAQT
tr_Q8WPD8ComplementcomponentC3      ---SLIRQPYGCGEQTMIYAGPTVFALQYLVTTGTITPNS----PEYNSA
tr_Q8TDJ3CD109_Homosapiens_Hum      -LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLK------EKA
tr_Q8IZJ3Alpha_2macroglobulinf      ---NLLRLPFGCGEQNMIHFAPNVFVLKYLQKTQQLSPEVER------ET
tr_Q7Q7S6AgCP4019_Anophelesgam      -LDHLLALSAGTGEDNMVKFVPNILVLDYLHAIGSKEQHLID------KA
                                        :   . * .*              *                     

tn_CAD66666ComplementC4_Oncorh      LQFTEQGYMRILTFKK---GDGSYGAWT-----HHPTSYWLTGLVVKVMS
tr_Q9I932ComplementC4B_Cyprinu      LDFIEQAYERILTFKK---PDGSYGAWL-----NYPTSTWLTALVVKVLS
sp_P01028_CO4_HUMANComplementC      VDLIQKGYMRIQQFRK---ADGSYAAWL-----SRDSSTWLTAFVLKVLS
sp_P01029_CO4_MOUSEComplementC      VDLIQKGYMRIQQFRK---NDGSFGAWL-----HRDSSTWLTAFVLKILS
tr_Q9I933ComplementC4A_Cyprinu      QSMIQTGYNTVLTYKK---VDGSYGAFL-----RTPSSIWLTAFIAKELT
tn_BAC82347ComplementC4_Triaki      IFHIETGYNKILGYKK---DDGSYGAWK-----TYPSSTWLTAFIVKILS
tr_Q9YIA5ComplementC3_Q2_Cypri      VNYINTGYQRQLGYRK---SDGSYAAWT-----HRPSSTWLTAYVAKVFS
tr_Q9YIA9ComplementC3_H1_Cypri      INHIKTGYQRQLGYRK---SDGSYAAWK-----DRPSSTWLTAYVAKVFS
tn_AAQ74974ComplementC3_Ctenop      INHINTGYQRQLSYRK---TEGSYAAWI-----DRPSSTWLTAYVAKVFA
tr_Q9YIA7ComplementC3_S_Cyprin      LNHIRTGYQRQLTYRK---SDGSYAAFT-----SRPSSTWLTAYVAKVFA
tr_Q9YIB0ComplementC3_H1_Cypri      INHINAGYQRQLGYRK---SDGSYAAWT-----HRPSSTWLTAYVAKVFS
sp_P98093_CO3_ONCMYComplementC      IKYINIGYQRQLAYRK---EDGSYAAWV-----SRQSSTWLTAYVVKVFA
tr_Q98TS6ComplementcomponentC3      LQHITTGYKRELNYRK---EDGSFAAFA-----ERPSSAWLTAYVAKVFA
tr_Q9PTY1ComplementcomponentC3      LQHIKTGYTNELAYRK---KDGSFSVWA-----SHGSSSWLTAYVAKVFA
tr_Q9IBH1OrlaC3_1protein_Oryzi      LQHIKTGYTNELAYLK---GDGSFAVWA-----DHGSSSWLTAYVIKVFS
tr_Q9IBH0OrlaC3_2protein_Oryzi      LQHIKTGYNNELAYIK---NDGSFAIYP-----RSPSSSWLTAYVVKVFS
sp_Q01833_CO3_NAJNAComplementC      IKQIMTGYAQQMVYKK---ADHSYAAFT-----NRASSSWLTAYVVKVLA
tr_Q91132Cobravenomfactorprecu      VNQIVTGYAQQMVYKK---ADHSYAAFT-----NRASSSWLTAYVVKVFA
tr_Q91588ComplementcomponentC3      LKNMRQGYAQQMAFRK---PDNSYAAWK-----DRPASTWLTGYVAKVFG
tr_Q90633ComplementC3precursor      IELIKKGYTQQLAYRK---EDGSFAAFT-----TRPSSTWLTAYVAKVFA
sp_P01024_CO3_HUMANComplementC      LELIKKGYTQQLAFRQ---PSSAFAAFV-----KRAPSTWLTAYVVKVFS
tr_Q80XP1Complementcomponent3_      LELIKKGYTQQLAFKQ---PSSAYAAFN-----NRPPSTWLTAYVVKVFS
sp_P01026_CO3_RATComplementC3p      LELIKKGYTQQLAFKQ---PISAYAAFN-----NRPPSTWLTAMWSRSFS
sp_P01027_CO3_MOUSEComplementC      LELIKKGYTQQLAFKQ---PSSAYAAFN-----NRPPSTWLTAYVVKVFS
sp_P12387_CO3_CAVPOComplementC      LNLINRGYTQQLAFKQ---PNWAYAAFK-----NRASSTWLTAYVVKVFS
tr_Q9GKP1ComplementcomponentC3      LELIKKGYTQQLAFRQ---KNSAFAAFQ-----DRLSSTLLTAYVVKVFA
sp_Q00685_CO3_LAMJAComplementC      IGFLKQGYSRELSYRK---ADHSYAAFI-----KRPSSTWLTAFVVKVYS
sp_P98094_CO3_EPTBUComplementC      FDFITSGFASQLTYRK---PDYSYAAWL-----HRASSTWLTAFVAKVFS
sp_P01031_CO5_HUMANComplementC      KKKLKEGMLSIMSYRN---ADYSYSVWK-----GGSASTWLTAFALRVLG
tr_Q8AYN9ComplementcomponentC5      KRKMQAGITSIMSFKLK--HEPAFSMWSKK---DKSASTWVTALIVKTLA
tr_Q969A4ComplementcomponentC3      YDFIRQGYNKQLSHRR---PEGCFSVWG--QNNRYPCSTWLTAFVNKVFC
tr_Q03626Alpha_1_inhibitorIIIp      LGYLRAGYQRELNYKHK---DGSYSAFGDH-NGQGQGNTWLTAFVLKSFA
tr_Q9PVU4Alpha_2_macroglobulin      TAFLKSGYQRQLNYRHT---SGAYSTFG-----HGDENTWLTAFVLRSFG
tr_O44344ComplementcomponentC3      YDYIADGVARELTYRQ---DNGAYAAWK-----HRPGSTWLTAFVVKVFS
tr_Q8I7P1ComplementcomponentC3      FNFIRSGYQRELNYRR---SDNSFSAFG----NSRAGSTWLTAFVIKTFC
tr_O97019AsC3protein_Halocynth      LKYIQDGYAHELEYKTQVPQGWAFAVWAN-----NPPSTWLNGFVSRVFA
tr_Q8WPD8ComplementcomponentC3      VNKIEAAFQREMTYRTTHTNPRVWSVFT-----HYLPSTWLNAFVDKVFY
tr_Q8TDJ3CD109_Homosapiens_Hum      LSFMRQGYQRELLYQR---EDGSFSAFG---NYDPSGSTWLSAFVLRCFL
tr_Q8IZJ3Alpha_2macroglobulinf      TDYLVQGYQRQLTYKR---QDGSYSAFG---ERDASGSMWLTAFVLKSFA
tr_Q7Q7S6AgCP4019_Anophelesgam      MNLVRLGYQNQMRYCQ---KDGSFGLWDN-----TGGNTFLTTFVATTMQ
                                          .      .         :. :          .  :.        

tn_CAD66666ComplementC4_Oncorh      LVAERQNAGGGEKGRWAQGVSEQHIIDSVRYLLVKQKEDGSFSDPNPVIH
tr_Q9I932ComplementC4B_Cyprinu      LVAERQIETLEQQGTTEKMISQMDIRHAVTYLIKTQSSDGSFTDANPVYH
sp_P01028_CO4_HUMANComplementC      LAQEQVGG------------SPEKLQETSNWLLSQQQADGSFQDPCPVLD
sp_P01029_CO4_MOUSEComplementC      LAQEQVGN------------SPEKLQETASWLLAQQLGDGSFHDPCPVIH
tr_Q9I933ComplementC4A_Cyprinu      ESRDIISVK------------DSYIQESMSYLMSKQKSNGAWDDPNQLYD
tn_BAC82347ComplementC4_Triaki      MARSKIVIN------------DSFIRESVAYLIRGQKSSGAFEDPHPVID
tr_Q9YIA5ComplementC3_Q2_Cypri      MANNIVN-----------IEENVICSALKWLILHKQTLYGSFKEDSAVIQ
tr_Q9YIA9ComplementC3_H1_Cypri      MANDFAT-----------IEKNVLCSALKWLVLHKQLPDGSFKEESAVIH
tn_AAQ74974ComplementC3_Ctenop      MASNFVA-----------IEENVICSALKWLVLNKQLPDGSFKEDSAVVH
tr_Q9YIA7ComplementC3_S_Cyprin      IANNLVT-----------IEENVICSALKWLVLHKQLPDGSFKEDSAVIS
tr_Q9YIB0ComplementC3_H1_Cypri      MANDFAA-----------IEENVLCSALKWLVLHKQLPDGSFKEESAVIH
sp_P98093_CO3_ONCMYComplementC      MSSTLIS-----------VQENVLCTAVKWLILNTQQPDGIFNEFAPVIH
tr_Q98TS6ComplementcomponentC3      MANSLVA-----------VQNNDICEAIKYLILNAQQPDGVFKDKAPVIH
tr_Q9PTY1ComplementcomponentC3      MANSLVA-----------VQNNVICDAVKYLILNAQQPDGVFKEVGRVAH
tr_Q9IBH1OrlaC3_1protein_Oryzi      MANNLVA-----------IKKEHICDAVKFLILRAQQPDGLFTETGKMYH
tr_Q9IBH0OrlaC3_2protein_Oryzi      MANNLVA-----------IRKNHICDAVKFLILRAQQPDGLFTEVGRVSA
sp_Q01833_CO3_NAJNAComplementC      MASNMVKD----------ISHEIICGGVKWLILNRQQPDGVFKENAPVIH
tr_Q91132Cobravenomfactorprecu      MAAKMVAG----------ISHEIICGGVRWLILNRQQPDGAFKENAPVLS
tr_Q91588ComplementcomponentC3      MAQ-EFID----------IEANVLCGSVKWLILEKQKPDGLFQENAPVIH
tr_Q90633ComplementC3precursor      MAINMVD-----------IKPEVVCGAIKWLILEKQQPDGLFQEDAPVIH
sp_P01024_CO3_HUMANComplementC      LAVNLIA-----------IDSQVLCGAVKWLILEKQKPDGVFQEDAPVIH
tr_Q80XP1Complementcomponent3_      LAANLIA-----------IDSHVLCGAVKWLILEKQKPDGVFQEDGPVIH
sp_P01026_CO3_RATComplementC3p      LAANLIA-----------IDSQVLCGAVKWLILEKQKPDGVFQEDGPVIH
sp_P01027_CO3_MOUSEComplementC      LAANLIA-----------IDSHVLCGAVKWLILEKQKPDGVFQEDGPVIH
sp_P12387_CO3_CAVPOComplementC      LAANLIG-----------IDSEVLCGAVKWLILEKQKPDGVFQEDGPVIH
tr_Q9GKP1ComplementcomponentC3      MAANLIA-----------IDSQVLCGAVKWLILEKQKPDGVFEENGPVIH
sp_Q00685_CO3_LAMJAComplementC      LAKRVII-----------VDNQELCGPVEWIIKNRQNSDGSYREDGPVIH
sp_P98094_CO3_EPTBUComplementC      QARQLVF-----------IPVSEICGSVRWLMR-KQDKDGSFLESKPVVH
sp_P01031_CO5_HUMANComplementC      QVNKYVE-----------QNQNSICNSLLWLVENYQLDNGSFKENSQYQP
tr_Q8AYN9ComplementcomponentC5      DMHEYIS-----------LESEVLTNTINWLIKNCQNDDGSFSEKSQTNP
tr_Q969A4ComplementcomponentC3      QAKKFVTS-----------IDEEAVCKATEWLLSTQREDGAFKEVYKVHH
tr_Q03626Alpha_1_inhibitorIIIp      QARAFIFID------------ESHITDAFTWLSKQQKDSGCFRSSGSLFN
tr_Q9PVU4Alpha_2_macroglobulin      KAQKYIFID------------PQIIQRAKEWLISRQDSDGCFIQQGRLFN
tr_O44344ComplementcomponentC3      QANRFTR-----------VEPGHVEGSINWLIDNNQLPSGAFQESQQVIH
tr_Q8I7P1ComplementcomponentC3      AIKKLDG----------IDIDQNVINTAINWLSSRQRADGAISESSPVIH
tr_O97019AsC3protein_Halocynth      SARKYWPG-----------MEVDRICQSVAWLLTQQEPDGHFDEDDPVHH
tr_Q8WPD8ComplementcomponentC3      HGRRYDTDMN-----------VGPICNSLNFLIGEQMAGEHFRERRPPLH
tr_Q8TDJ3CD109_Homosapiens_Hum      EADPYIDID------------QNVLHRTYTWLKGHQKSNGEFWDPGRVIH
tr_Q8IZJ3Alpha_2macroglobulinf      QARSFIFVD------------PRELAAAKSWIIQQQQADGSFLAVGRVLN
tr_Q7Q7S6AgCP4019_Anophelesgam      TASKYIVEID-----------AEIVDRALDWLASKQHSSGRIDEVGAVFH
                                                                   :   *              

tn_CAD66666ComplementC4_Oncorh      REMQGGIGGM--EGDVSMTAFLTVALNRSLPFLTDNKERRLRKPLSPKAT
tr_Q9I932ComplementC4B_Cyprinu      REMQGGIGGV--EQDASLTAFITIALYRSLPYLDEEVTDVNKS--ISLAT
sp_P01028_CO4_HUMANComplementC      RSMQGGLVGN--DETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASIS
sp_P01029_CO4_MOUSEComplementC      RAMQGGLVGS--DETVALTAFVVIALHHGLDVFQDDDAKQLKNRVEASIT
tr_Q9I933ComplementC4A_Cyprinu      RGMKGGVGKA--KDDVPLTAFILISMNHALKLYELGSDTELR---VAMDR
tn_BAC82347ComplementC4_Triaki      RNMQGGVDGT--EKDVSLTAFVTIALKHSLTAFPQNNIAEISRVERSIGK
tr_Q9YIA5ComplementC3_Q2_Cypri      GEMVGGIQSK--DADASLTAFVVIAMQEAREICAGSVASLHESIRKAVSF
tr_Q9YIA9ComplementC3_H1_Cypri      GEMVGDVRGK--DADASLTAFVVIAMQEAREICGESVGSLHESIRKAVVF
tn_AAQ74974ComplementC3_Ctenop      GEMVGDVRGK--DADASLTAFVVIAMQEGREICAGAVGSLHESIKKAVDF
tr_Q9YIA7ComplementC3_S_Cyprin      SGMVGDVQGQ--NADASLTAFVVIAMQEGREICAGSVASLQESIRKAVSF
tr_Q9YIB0ComplementC3_H1_Cypri      GEMVGDVRGK--DADASLTAFVVIAMQEAREICGGSVGSLHDSIKKAVVF
sp_P98093_CO3_ONCMYComplementC      AEMTGNVRGS--DNDASMTAFVLIAMQEASSVCEQSVNSLPGSMAKAVAY
tr_Q98TS6ComplementcomponentC3      GEMTGECSRR--RFRCLHDGLLPHCHAGSRTVCTATVNSLHASIGKAVVY
tr_Q9PTY1ComplementcomponentC3      GEMIGDVRGT--DSEASMTAFCLIAMQESRTLCAATVNSLPGSVEKSVLY
tr_Q9IBH1OrlaC3_1protein_Oryzi      GEMIGDVRGS--DSDASMTAFCLIAMQESRSLCSATVNTLPGSIDKAVAY
tr_Q9IBH0OrlaC3_2protein_Oryzi      GYMTGDVQGY--DSDASMTAFCLIAMQESRSVCEGYINNLPGSINRAVAY
sp_Q01833_CO3_NAJNAComplementC      GEMLGGTKG--AEPEASLTAFIVTALLESRSVCKEQINILDSSINKATDY
tr_Q91132Cobravenomfactorprecu      GTMQGGIQG--AEEEVYLTAFILVALLESKTICNDYVNSLDSSIKKATNY
tr_Q91588ComplementcomponentC3      QEMVGGITTGAAEGDSSLTAFILIAMLECQRTCNEHVNNLQVSIDKASSY
tr_Q90633ComplementC3precursor      KEMVGGYHGA-EPS-VSLTAFVLSALQESQKICKNYVKSLDGSIAKASDY
sp_P01024_CO3_HUMANComplementC      QEMIGGLRNN-NEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF
tr_Q80XP1Complementcomponent3_      QEMIGGFRNA-KEADVSLTAFVLIALQEARDICEGQVNSLPGSINKAGEY
sp_P01026_CO3_RATComplementC3p      QEMIGGFRNT-KEADVSLTAFVLIALQEARDICEGQVNSLPGSINKAGEY
sp_P01027_CO3_MOUSEComplementC      QEMIGGFRNA-KEADVSLTAFVLIALQEARDICEGQVNSLPGSINKAGEY
sp_P12387_CO3_CAVPOComplementC      QEMIGGVRTA-QEADVSLTAFVLIALQEAKDICRAQVNNLEANINKAGDY
tr_Q9GKP1ComplementcomponentC3      QEMIGGFKNT-EEKDVSLTAFVLIALQEAKDICEPQVNSLLRSINKARDF
sp_Q00685_CO3_LAMJAComplementC      REMQGGVGGT--EGHVSMTAFILIGIQQAQEYCGVSVPNYKQSMNRAVQF
sp_P98094_CO3_EPTBUComplementC      LNMMGQVTGK-----VVLTSFVFIALLEARESCINEVEGFTVVVEKAHGY
sp_P01031_CO5_HUMANComplementC      IKLQGTLPVEARENSLYLTAFTVIGIRKAFDIC--PLVKIDTALIKADNF
tr_Q8AYN9ComplementcomponentC5      LKLMGAG-ADVTEKTVFLTSFVMIGIKNAMKVPNVNLEVFKIAIDRAVQY
tr_Q969A4ComplementcomponentC3      REMTGGVQGD-----ASMTAFVLISLLEN---CECPIAERSIAIERATLF
tr_Q03626Alpha_1_inhibitorIIIp      NAMKGGVDDE-----ITLSAYITMALLESSLPDTDPVVSKALGCLEASWE
tr_Q9PVU4Alpha_2_macroglobulin      NRMKGGVNDN-----VTMTAYITASLLELETPVTDLVVSKGLSCLKSVVK
tr_O44344ComplementcomponentC3      QEMIGAVKGE-----TSMTAFVLISLLESRNLLVPANQKIDEAIGKATEY
tr_Q8I7P1ComplementcomponentC3      QEMNGDITGD-----IAMTAYVVTAFLECESVAPNSVQTVKRAVAYLENM
tr_O97019AsC3protein_Halocynth      KEMDGQVTND-----ITMTAFICISLYESRSSCPELSTRIQEGVNSAMEY
tr_Q8WPD8ComplementcomponentC3      REMHGAVKGP-----MTLTAHVAISMGEINSICLPELNQRVIASRVSAMN
tr_Q8TDJ3CD109_Homosapiens_Hum      SELQGGNKSP-----VTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS
tr_Q8IZJ3Alpha_2macroglobulinf      KDIQGGIHGI-----VPLTAYVVVALLETGTASEEERGSTDKARHFLESA
tr_Q7Q7S6AgCP4019_Anophelesgam      KDMKGGLRDG-----VALTSFVLTALLENNIAKVKYAEAIQKGMSYLSNQ
                                      : *              .                              

tn_CAD66666ComplementC4_Oncorh      DYLLLR----VEGLQRPYAVAITAYCLSVCLTDRKQAEPAWEKLKGLATE
tr_Q9I932ComplementC4B_Cyprinu      NFLLKR----VGDLKRPYALAITAYCLSVCLTDRTQSLSAWRKLKSLAKP
sp_P01028_CO4_HUMANComplementC      KANSFLGEKASAGLLGAHAAAITAYALSLTKAPVDLLGVAHNNLMAMAQE
sp_P01029_CO4_MOUSEComplementC      KANSFLGQKASAGLLGAHAAAITAYALTLTKASEDLRNVAHNSLMAMAEE
tr_Q9I933ComplementC4A_Cyprinu      AKSYLEG--QLDALESPYSLAITAYALSLHDQQSANAQRAHRKLKNIANC
tn_BAC82347ComplementC4_Triaki      AVEFLHK--MFPYVILPHTFAITAYAFAFVGADTDIVFEADRKLRAIASY
tr_Q9YIA5ComplementC3_Q2_Cypri      LEGRLPQ------LTNPYAVAMMSYAMANENKLNKDILMKHSSQHEAGRS
tr_Q9YIA9ComplementC3_H1_Cypri      LEGRVPQ------LTNPYAVAMTSYAMANENKLNKDILMKYSSQHEAGRS
tn_AAQ74974ComplementC3_Ctenop      LEGRLPR------LTNPYAVAMTSYALANSEKLNKDILMKHSTQGEAGRF
tr_Q9YIA7ComplementC3_S_Cyprin      LEGRLPQ------LTNPYAVAMTSYAMASENKLKNDILMRHSTQQEASRS
tr_Q9YIB0ComplementC3_H1_Cypri      LEGRLPQ------LTNPYAVAMTSYAMANAGKLNKDILMKYSSQHEAGRS
sp_P98093_CO3_ONCMYComplementC      LEKRLPH------LTNPYAVAMTSYALANAGKLNKETLLKFASPQLDH--
tr_Q98TS6ComplementcomponentC3      LERRLPS------LTNPYAVAMTSYALANENKLNQDILYNFVSPDLSH--
tr_Q9PTY1ComplementcomponentC3      LERRLES------LTNPYAVAITSYALANEGRLNKDVLYKFASPELSH--
tr_Q9IBH1OrlaC3_1protein_Oryzi      LEKRLPR------LTNPYAVAMTSYALANEGKLNRDILYKFVSPELT--H
tr_Q9IBH0OrlaC3_2protein_Oryzi      LEKRLPS------LTNPYAVAMTSYALANEGKLNRQILYKFVSPELSH--
sp_Q01833_CO3_NAJNAComplementC      LLKKYEK------LQRPYTTALTAYALAAADRLND--DRVLMAASTGRNR
tr_Q91132Cobravenomfactorprecu      LLKKYEK------LQRPYTTALTAYALAAADQLND--DRVLMAASTGRDH
tr_Q91588ComplementcomponentC3      LVGQYPG------LKKPYSIAITSYALALAGKLPN--TNKLLSASIGNTH
tr_Q90633ComplementC3precursor      LSRKYQS------LTRPYTVALTSYALALTGKLN--SEKVLMKFSKDGTH
sp_P01024_CO3_HUMANComplementC      LEANYMN------LQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR
tr_Q80XP1Complementcomponent3_      IEASYMN------LQRPYTVAIAGYALALMNKLEEPYLGKFLNTAKDRNR
sp_P01026_CO3_RATComplementC3p      LEASYLN------LQRPYTVAIAGYALALMNKLEEPYLTKFLNTAKDRNR
sp_P01027_CO3_MOUSEComplementC      IEASYMN------LQRPYTVAIAGYALALMNKLEEPYLGKFLNTAKDRNR
sp_P12387_CO3_CAVPOComplementC      IESRYAD------VRRPYTLAIAGYALALLERLNGATLQKFLNAATEKNR
tr_Q9GKP1ComplementcomponentC3      LADYYLE------LKRPYTVAIAGYALALSDKLDEPFLNKLLSTAKERNR
sp_Q00685_CO3_LAMJAComplementC      LASKVSD------LKRMYTIAITRYALALQDPESEAAHSSWKKLENRTTF
sp_P98094_CO3_EPTBUComplementC      LTSQAMN------GLEDFPLAITAYALSLWKVSDGAAKVTMHTLKTSGLQ
sp_P01031_CO5_HUMANComplementC      LLENTLP------AQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALV
tr_Q8AYN9ComplementcomponentC5      ITSNSKK------IKSLYARAIASYALTLADIHSMSAVEVYEILKKQAQV
tr_Q969A4ComplementcomponentC3      LERQLEQ------LKRPYVIAIVTYALHLADSPLKGAANEKLRSIAKYDE
tr_Q03626Alpha_1_inhibitorIIIp      TIEQGRN------GSFVYTKTLMAYAFALAGNQEKRNEILKSLDKEAIRE
tr_Q9PVU4Alpha_2_macroglobulin      DVEN------------TYSTALLAYTFSLAKDTDTRQQLFKKLEDVAISD
tr_O44344ComplementcomponentC3      LVTQVEN------IDRVYDKALVTSALRESASVGTANGKLWEDRNEDGTG
tr_Q8I7P1ComplementcomponentC3      QPNVGRVY---VKAVIAYALALADSPLEVKRQSRTVEQCSLLCRQEHRRY
tr_O97019AsC3protein_Halocynth      LKNHFDD-----AKNTPYTVAIVAYAFAIWEPHGQFAQKWNEQLVAMKIE
tr_Q8WPD8ComplementcomponentC3      YLEQHKD---HATFQRPYPLSLLAYAAALHNPRSQLAIEMNARLMAMKQT
tr_Q8TDJ3CD109_Homosapiens_Hum      RGISDNY-----------TLALITYALSSVGSPKAKEALNMLTWRAEQEG
tr_Q8IZJ3Alpha_2macroglobulinf      APLAMDP----------YSCALTTYALTLLRSPAAPEALRKLRSLAIMRD
tr_Q7Q7S6AgCP4019_Anophelesgam      FGSINNA----------YDLSIATYAMMLNGHIMKEESLNKLINMSFINA
                                                        ::                            

tn_CAD66666ComplementC4_Oncorh      GKDNCRG-WYANAG-------MVNEEKKHYVPTTEAITVETTAYALLTAV
tr_Q9I932ComplementC4B_Cyprinu      AEECLVWQDDENAR-------LVNEAKTNRVPPGVALTVETTAYALLTAL
sp_P01028_CO4_HUMANComplementC      TGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLL
sp_P01029_CO4_MOUSEComplementC      TGEHLYWGLVLGSQDKVVLRPTAPRSPTEPVPQAPALWIETTAYALLHLL
tr_Q9I933ComplementC4A_Cyprinu      DTTK--CFWNSSGG------------RGESAGKANAESVETTAYALLSAL
tn_BAC82347ComplementC4_Triaki      DTEQDIRYWKVDET------------LTPSGKQASAITVETTSYALLQTL
tr_Q9YIA5ComplementC3_Q2_Cypri      WTVPGQH----------------------------HHSLEATAYAVLALV
tr_Q9YIA9ComplementC3_H1_Cypri      WTVPGQH----------------------------YHSLEATAYAVLALV
tn_AAQ74974ComplementC3_Ctenop      WNVAGQP----------------------------HHSREATAYAVLALV
tr_Q9YIA7ComplementC3_S_Cyprin      WTVPGQH----------------------------HHSLEATAYAVLALV
tr_Q9YIB0ComplementC3_H1_Cypri      WTVPGQH----------------------------HHSLEATAYAVLALV
sp_P98093_CO3_ONCMYComplementC      WPVPGGY----------------------------QYTLEATSYALLALV
tr_Q98TS6ComplementcomponentC3      WPTPKGR----------------------------VYTLEATAYALLALV
tr_Q9PTY1ComplementcomponentC3      WPVPKGR----------------------------VYTLEATAYALLALV
tr_Q9IBH1OrlaC3_1protein_Oryzi      WPVPGKH----------------------------LFTLEATAYALLALV
tr_Q9IBH0OrlaC3_2protein_Oryzi      WPVPGRH----------------------------VFTLEATAYALLALV
sp_Q01833_CO3_NAJNAComplementC      WEEYNAR----------------------------THNIEGTSYALLALL
tr_Q91132Cobravenomfactorprecu      WEEYNAH----------------------------THNIEGTSYALLALL
tr_Q91588ComplementcomponentC3      WEEPGKR----------------------------FISLETTSYALLTLL
tr_Q90633ComplementC3precursor      WAERNAH----------------------------TYNIEGTSYALVALL
sp_P01024_CO3_HUMANComplementC      WEDPGKQ----------------------------LYNVEATSYALLALL
tr_Q80XP1Complementcomponent3_      WEEPDQQ----------------------------LYNVEATSYALLALL
sp_P01026_CO3_RATComplementC3p      WEEPGQQ----------------------------LYNVEATSYALLALL
sp_P01027_CO3_MOUSEComplementC      WEEPDQQ----------------------------LYNVEATSYALLALL
sp_P12387_CO3_CAVPOComplementC      WEEARQK----------------------------LYSVEATSYALLALL
tr_Q9GKP1ComplementcomponentC3      WEEPGQK----------------------------LHNVEATSYALLALL
sp_Q00685_CO3_LAMJAComplementC      ESKGHRYWKAEETSHVLR---------------MSAISVEATAYGLLTYL
sp_P98094_CO3_EPTBUComplementC      TEELIHWGSNK----------------------GKAAAVESTAYGLLAAI
sp_P01031_CO5_HUMANComplementC      KGNPPIYRFWKDNLQHKDS---------SVPNTGTARMVETTAYALLTSL
tr_Q8AYN9ComplementcomponentC5      DGNPATVRFWQEYKLGKDS---------LKPSDATAKTVETTVYVLLNTL
tr_Q969A4ComplementcomponentC3      GTNSRYWEADASSIADGQQ-------PYWYTRKPSAIAVETTAYALLTQM
tr_Q03626Alpha_1_inhibitorIIIp      DNSIHWERPQKPTKSEGYL----------YTPQASSAEVEMSAYVVLARL
tr_Q9PVU4Alpha_2_macroglobulin      GSHLHWSQSG--------------------SVDSDSLAVEISSYVLLAVL
tr_O44344ComplementcomponentC3      AVSFTPDDANYEDGSQPFWLQ----------RKPSAIEIETSGYALLAQL
tr_Q8I7P1ComplementcomponentC3      WHRRSGG--------------------------NAIEPSKRTSYALANTN
tr_O97019AsC3protein_Halocynth      DEKFVHWQGTRG----------------------RAADIETTAYGLLAEI
tr_Q8WPD8ComplementcomponentC3      SGNGAYVFWRAKTLAEISG---TNAHAYWYRTRPLALDIETTSYALLAQV
tr_Q8TDJ3CD109_Homosapiens_Hum      GMQFWVSSESKLSDSWQPR----------------SLDIEVAAYALLSHF
tr_Q8IZJ3Alpha_2macroglobulinf      GVTHWSLSNSWDVDKGTFLS-----FSDRVSQSVVSAEVEMTAYALLTYT
tr_Q7Q7S6AgCP4019_Anophelesgam      DKNERFWN--------------------------TTNPIETTAYALLSFV
                                                                           : : * :    

tn_CAD66666ComplementC4_Oncorh      AHK---------DAEWADSAACWLTSQENYGGGFKSTQDTIVALEALSEY
tr_Q9I932ComplementC4B_Cyprinu      VQN---------DLITADAAACFLSSQENYEGGFKSTQDTIMALEALSEY
sp_P01028_CO4_HUMANComplementC      LHE--------GKAEMADQASAWLTRQGSFQGGFRSTQDTVIALDALSAY
sp_P01029_CO4_MOUSEComplementC      LRE--------GKGKMADKAASWLTHQGSFHGAFRSTQDTVVTLDALSAY
tr_Q9I933ComplementC4A_Cyprinu      SLR---------DKAYAKLTANWLTEQRKYGGGFQSTQDTVVALEALTKY
tn_BAC82347ComplementC4_Triaki      SRN---------GIDYAMPIVNWLTEQQNYGGGFRSTQDTVIALEALSQY
tr_Q9YIA5ComplementC3_Q2_Cypri      KAK---------DFDKAGEAVHWLNRQQSHYGGSGTTQATIMVFQAVAEY
tr_Q9YIA9ComplementC3_H1_Cypri      KEK---------DFDKAGEAVHWLNRQQSHYGGSGTTQATIMVFQAVAEY
tn_AAQ74974ComplementC3_Ctenop      KAR---------DFDKAGEAVHWLGRQQSHYGGSGTTQATIIVFQAVAEY
tr_Q9YIA7ComplementC3_S_Cyprin      RDR---------DFDKAGEAVHWLARQQAHYGGYGTTQATIMVFQAVAEY
tr_Q9YIB0ComplementC3_H1_Cypri      KAK---------DFDKAGEAVHWLNRQKSHYGGSGTTQATIMVFQAVAEY
sp_P98093_CO3_ONCMYComplementC      KVK---------AFEEAGPIVRWLNKQKKVGGGYGSTQSTIMVFQAVAEY
tr_Q98TS6ComplementcomponentC3      KAK---------AFEEARPVVRWFNKQQKVGGGYGSTQATILVYQAIAEY
tr_Q9PTY1ComplementcomponentC3      KTK---------DFEKARPIVRWFSQQQKVGGGYGSTQATIIVYQAVAEY
tr_Q9IBH1OrlaC3_1protein_Oryzi      KTK---------SFEDARPVVRWFNQQQFVGGGYGSTQATIIVYQAVAEY
tr_Q9IBH0OrlaC3_2protein_Oryzi      KTK---------SFEDARPVVRWFNQQQFVGGGYGSTQATIIVYQALAEY
sp_Q01833_CO3_NAJNAComplementC      KMK---------KFAEVGPVVRWLIDQKYYGGTYGQTQATVMVFQALAEY
tr_Q91132Cobravenomfactorprecu      KMK---------KFDQTGPIVRWLTDQNFYGETYGQTQATVMAFQALAEY
tr_Q91588ComplementcomponentC3      KMK---------EFDLTGGIVRWLNEQRYYGAVYGSTQATIVMFQALAQY
tr_Q90633ComplementC3precursor      QME---------KAELTGPVVRWLAQQNYFGGGYGSTQATILVFQALAQY
sp_P01024_CO3_HUMANComplementC      QLK---------DFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQY
tr_Q80XP1Complementcomponent3_      LLK---------DFDSVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQY
sp_P01026_CO3_RATComplementC3p      LLK---------DFDSVPPVVRWLNDERYYGGGYGSTQATFMVFQALAQY
sp_P01027_CO3_MOUSEComplementC      LLK---------DFDSVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQY
sp_P12387_CO3_CAVPOComplementC      LLK---------DFDAVPPVVRWLNEQRYYGRGYGSTQATFMVFQALAQY
tr_Q9GKP1ComplementcomponentC3      VVK---------DFDSVPPIVRWLNEQRYYGGGYGSTQATFMVFQALAQY
sp_Q00685_CO3_LAMJAComplementC      RKK---------DYESAREIVDWLTEQRNYGGGFQSTQDTILALQAMAQY
sp_P98094_CO3_EPTBUComplementC      QHE---------EGEIAEKATNWLSQSATFGGYFQSTQDTVMALQALTGF
sp_P01031_CO5_HUMANComplementC      NLK---------DINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEY
tr_Q8AYN9ComplementcomponentC5      VRG---------DTTYAKPILNWLTQDQRYGGGVHSTQDSILTLEALTKY
tr_Q969A4ComplementcomponentC3      HIG---------DIQYSNPIVVWLTQQRNSAGGFVSTQDTVVALQALSSY
tr_Q03626Alpha_1_inhibitorIIIp      TAQPAPS--PE-DLALSMGTIKWLTKQQNSHGGFSSTQDTVVALDALSKY
tr_Q9PVU4Alpha_2_macroglobulin      TADSLTS---A-DLGFANRIVSWLVKQQNAYGGFSSTQDTVVALQALSLY
tr_O44344ComplementcomponentC3      ALL---------DYQKAGKIALWLSKQQNDGGGFVSPQDTVVALQALAKY
tr_Q8I7P1ComplementcomponentC3      GSE---------QAWLRRSYRCLADGTKRGGGGFISTQDTCVALQALAAY
tr_O97019AsC3protein_Halocynth      SLKKVTE--N--NYRWTKQIANWLISQRNDRGGFISTQDTVVAIEALTKY
tr_Q8WPD8ComplementcomponentC3      AMSKAKDPLVQADLDLGRKISLWLISQRNSNGGFRSTQDTVIGLQALSTI
tr_Q8TDJ3CD109_Homosapiens_Hum      LQF---------QTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEF
tr_Q8IZJ3Alpha_2macroglobulinf      LLG---------DVAAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEY
tr_Q7Q7S6AgCP4019_Anophelesgam      MAEK---------YLDGIPVMNWLVNQRYVTGSFPSTQDTFVGLKALTKM
                                                                        .* :    ..::  

tn_CAD66666ComplementC4_Oncorh      ALNRPQPPITEVEVQFTIPGKS---DIQKLSLDNKGDKVETELKRLIGNP
tr_Q9I932ComplementC4B_Cyprinu      ALSVPESPFRTVNALFTIQGRS---EMEKLTLD-KSEKVETELKRLVG-T
sp_P01028_CO4_HUMANComplementC      WIASHTTEERGLNVTLSSTGRNGF-KSHALQLNNRQIRGLEEELQFSLGS
sp_P01029_CO4_MOUSEComplementC      WIASHTTEEKALKVTLSSMGRNGL-KTHGLHLNNHQVKGLEEELKFSLGS
tr_Q9I933ComplementC4A_Cyprinu      SMQNND-VDDLDLRVEMCLENG---KKQD-LHLTKNNALTAEAVKVRNVG
tn_BAC82347ComplementC4_Triaki      HIAFLKREEEIDMQIHFNVLGS---PTENNIHLRRRNALTQKELKFPLGS
tr_Q9YIA5ComplementC3_Q2_Cypri      RTQVKDQQNFNLDVELSVAGRG---KPVRYTIKRENAHLTW-SHKMEINK
tr_Q9YIA9ComplementC3_H1_Cypri      RTQVKDRQNFNLDVELSVAGRS---KPVRYTIKKENAHLTR-SDRVDINK
tn_AAQ74974ComplementC3_Ctenop      RTQVKDQQNFNLDVELAVAGRS---KPVRWTIKKDTAHLTR-SDKVEINK
tr_Q9YIA7ComplementC3_S_Cyprin      RTQVKDTQNFNLDVELSVAGRS---KPVRWTFKRDNAHLIRSDRV-EINK
tr_Q9YIB0ComplementC3_H1_Cypri      RTQVKDRQNFNLDVELSVAGRG---KPVRYTIKRENAHLTR-SDRVDINK
sp_P98093_CO3_ONCMYComplementC      WSHVKDLKDFDLNINLEVAGRA---SVTKWSINNKNQFHTRTDKVNSIDK
tr_Q98TS6ComplementcomponentC3      WASAKEPE-YDLNVDILFTGRS---RPDKFNFNRNNHYATRTSKINDIHQ
tr_Q9PTY1ComplementcomponentC3      WAAAKEPE-YDLNVDILLPGRS---KPEKIVLNADNSYTTRTSKINDINQ
tr_Q9IBH1OrlaC3_1protein_Oryzi      WANAQEPE-YDLKVDILLPGKS---KPDKYEFNRENSYATRTSKIKDINK
tr_Q9IBH0OrlaC3_2protein_Oryzi      WTNAQEPQ-YDLKVDVLLPGKS---KPDKYQFTRENSYATRTSNIKNINK
sp_Q01833_CO3_NAJNAComplementC      EIQMPTHQDLNLDISIKLPERE---VPERYSINDRNAVQAR-TVETKLNE
tr_Q91132Cobravenomfactorprecu      EIQMPTHKDLNLDITIELPDRE---VPIRYRINYENALLAR-TVETKLNQ
tr_Q91588ComplementcomponentC3      QTDIPSVNELNLDVSLHLPERQ---QPLTYRINHENALLAR-SAETRLNQ
tr_Q90633ComplementC3precursor      HVALPRHVELNLDVSVLLPRRA---NAITYRIENNNALVAR-SAETKLNE
sp_P01024_CO3_HUMANComplementC      QKDAPDHQELNLDVSLQLPSRS---SKITHRIHWESASLLR-SEETKENE
tr_Q80XP1Complementcomponent3_      QTDVPDHKDLNMDVSFHLPSRS---SATTFRLLWENGNLLR-SEETKQNE
sp_P01026_CO3_RATComplementC3p      RADVPDHKDLNMDVSLHLPSRS---SPTVFRLLWESGSLLR-SEETKQNE
sp_P01027_CO3_MOUSEComplementC      QTDVPDHKDLNMDVSFHLPSRS---SATTFRLLWENGNLLR-SEETKQNE
sp_P12387_CO3_CAVPOComplementC      QTDVPDHKDLNMEVALQLPSRS---SPSKFRLVWEAGSLLR-SEATKQNE
tr_Q9GKP1ComplementcomponentC3      QKDVPDHKDLNLDVSIHLPSRS---APVRHRILWESASLLR-SEETKENE
sp_Q00685_CO3_LAMJAComplementC      KMDSSSKELIDVQLEITSPKNN---FEKKMKITEETRFVQEPHKIPPGGN
sp_P98094_CO3_EPTBUComplementC      ESCQSRMKKMDLSFKIRAEENG---VFDKEFQITNDNAFVQKPFKVPVHG
sp_P01031_CO5_HUMANComplementC      SLLVKQLR-LSMDIDVSYKHKG---ALHNYKMTDKN-FLGRPVEVLLNDD
tr_Q8AYN9ComplementcomponentC5      SILASQAT-LNMVVDIEYKTKG---DIRRITLTQQN-PVHKPIEVTKNDD
tr_Q969A4ComplementcomponentC3      CG---STKVDPTQFTCQMTSDNDL-DYNEEIHVDKDNALINQEKTAPVGG
tr_Q03626Alpha_1_inhibitorIIIp      GAATFSKSQKTP-LVTIQSSGSF---SQKFQVDNSNRLLLQQVSLPDIPG
tr_Q9PVU4Alpha_2_macroglobulin      ATKVFSSDGSS--TVTVQSAAD----THRFDLNQDNKLLYQEKQLQNVPA
tr_O44344ComplementcomponentC3      TE---RPEFNTIEMNCDVATEQIP-LHRYHIGNDNAKVQEEVDVSPSIGR
tr_Q8I7P1ComplementcomponentC3      SEKTGGDQ---MDLRIEVSTDG-DYKKTLIVNQKNALVQQQLDISSLIGD
tr_O97019AsC3protein_Halocynth      MTMLETAFQKENVDLRVILSST----SQHSSWFENPEVVGITENDGMTRK
tr_Q8WPD8ComplementcomponentC3      LSWISTVEPGIANPRIDFEMEG---AAGSAWAPPNAYTNHIDNTNQRLKK
tr_Q8TDJ3CD109_Homosapiens_Hum      AALMNTERTNIQVTVTGPSSPS---PVKFLIDTHNRLLLQTAELAVVQPM
tr_Q8IZJ3Alpha_2macroglobulinf      AILSYAGG---INLTVSLASTN-LDYQETFELHRTNQKVLQTAAIPSLPT
tr_Q7Q7S6AgCP4019_Anophelesgam      AEKISPSRNDYTVQLKYGKDSR------IFRINSEHIDVMNYVGIPEDTR
                                                                                      

tn_CAD66666ComplementC4_Oncorh      IIDVALTGQGKAKMKVTKAYHLLDTA-DDCNLLSITVKVEGRVEYTAQIV
tr_Q9I932ComplementC4B_Cyprinu      GIDVNLSGKGKIKMKVAKAYYAHKED-SNCADLSINVTVEGKVEYTSYVQ
sp_P01028_CO4_HUMANComplementC      KINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEAN
sp_P01029_CO4_MOUSEComplementC      TISVKVEGNSKGTLKILRTYNVLDMKNTTCQDLQIEVKVTGAVEYAWDAN
tr_Q9I933ComplementC4A_Cyprinu      KVSLNVQGTGRGTLAIVQTYRTMKKDESHCDLFHLSVTVKGELEYKIYNT
tn_BAC82347ComplementC4_Triaki      RIRIELSGQGNGTLNFRKSYHLMEEPSSTCKTVHLSVTVKGQLEFRKPYD
tr_Q9YIA5ComplementC3_Q2_Cypri      EFNVTARGTGRATLSVLTLYYARPVEKKSDCTFFDLTVKMEKNNE-----
tr_Q9YIA9ComplementC3_H1_Cypri      EFNVTAKGTGTATLSVLTLYYARPVEKKSDCTFFDLTVKMEKDNE-----
tn_AAQ74974ComplementC3_Ctenop      DFNVTARGTGTATLSVLTLYYARPIEKKSDCTFFDLTVKMEEDPE-----
tr_Q9YIA7ComplementC3_S_Cyprin      DFSVTARGTGKATLSVLTLYYARPAVKKSDCTLFDLTVKMEEDNK-----
tr_Q9YIB0ComplementC3_H1_Cypri      EFNVTARGTGTATLSVLTLYYARPVEKKSDCTFFDLTVKMEKDN------
sp_P98093_CO3_ONCMYComplementC      DLTVKASGNGEATLSVVTLYYALPEEKDSDCESFDLSVTLTKMDK-----
tr_Q98TS6ComplementcomponentC3      NMTVTASGSGEATLTMVSLYYAHPKEKESDCQKFDMTVQLLPAEK-----
tr_Q9PTY1ComplementcomponentC3      DVKVTAKGTGEATVTMVSLYYALPQKKESDCQKFNMSVELIPER------
tr_Q9IBH1OrlaC3_1protein_Oryzi      DIKVKATGSGEAVLKMVSLYYALPEEKESDCQKFDVSVQLLP--------
tr_Q9IBH0OrlaC3_2protein_Oryzi      DIKVKATGSGEAVVNMVSLYYALPEEKESDCQKFDMSVQLLPD-------
sp_Q01833_CO3_NAJNAComplementC      DFTVSASGDGKATMTILTVYNAQLREDANVCNKFHLDVSVENVEL-----
tr_Q91132Cobravenomfactorprecu      DITVTASGDGKATMTILTFYNAQLQEKANVCNKFHLNVSVENIHL-----
tr_Q91588ComplementcomponentC3      DFVVKAKGKGQGTMRVVTVYHALVTEKERKCLNFHLSVKVEEVEL-----
tr_Q90633ComplementC3precursor      DFTVKAEGTGKGTMTVVTVYKAKVPEKENKCDNFDLRVSVEDVKA-----
sp_P01024_CO3_HUMANComplementC      GFTVTAEGKGQGTLSVVTMYHAKAKDQL-TCNKFDLKVTIKPAPE-----
tr_Q80XP1Complementcomponent3_      AFSLTAKGKGRGTLSVVAVYHAKLKSKV-TCKKFDLRVSIRPAPE-----
sp_P01026_CO3_RATComplementC3p      GFSLTAKGKGQGTLSVVTVYHAKVKGKT-TCKKFDLRVTIKPAPE-----
sp_P01027_CO3_MOUSEComplementC      AFSLTAKGKGRGTLSVVAVYHAKLKSKV-TCKKFDLRVSIRPAPE-----
sp_P12387_CO3_CAVPOComplementC      GFKLTAKGKGQGTLSVVAVYYAKT-KRKVVCKNFDLRVTLKPAPD-----
tr_Q9GKP1ComplementcomponentC3      GFTLIAEGKGQGTLSVVTMYHGKAKGKT-TCKKFDLKVSIHPAPE-----
sp_Q00685_CO3_LAMJAComplementC      -ITIKASGRGTFTLSIMSVFNKVAPSSK-SCSTFDLKVTMTEADDGESPQ
sp_P98094_CO3_EPTBUComplementC      QLTVTASGTGQGILTFVKKYREKVVIKK-DCKGFSLEITTNLDNQVK---
sp_P01031_CO5_HUMANComplementC      LIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASH-----
tr_Q8AYN9ComplementcomponentC5      IIIKTAMSSGVSFASLRTVFYEMTENNENCYFDMSIDIHEGVPNS-----
tr_Q969A4ComplementcomponentC3      KLFLSTSGTGIGQMQVEVRYHTPDVHRERCLFEVVVTTEEAEGPVEPDEE
tr_Q03626Alpha_1_inhibitorIIIp      NYTVSVSGEGCVYAQTTLRYNMPLEKQQPAFALKVQTVPLTCNNPKGQ--
tr_Q9PVU4Alpha_2_macroglobulin      KYSIEVKGSTCVSVQVAQFYNIPTPTEAKTLSIDAKIEGDCKTLEQN---
tr_O44344ComplementcomponentC3      SLTFDSRGTGVAKANVELRYNTEKSDIDTCPFHLNISAVEVPSDE-----
tr_Q8I7P1ComplementcomponentC3      ELFIKTKGSGVAQLQVETRYNTPPTEKEVCQFDLRVITIERARRMYDQPI
tr_O97019AsC3protein_Halocynth      TVEVPKDAIDKPIRARVDGTGEGSLSYRCTWRQYESADKCHFQVEVS---
tr_Q8WPD8ComplementcomponentC3      QMAVPKNVIEGTIVDVTSRGQGQGILSYRCTYRTVVDEESCHYNLSTN--
tr_Q8TDJ3CD109_Homosapiens_Hum      AVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVK---
tr_Q8IZJ3Alpha_2macroglobulinf      GLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSLQEPEAQGRPPPMP
tr_Q7Q7S6AgCP4019_Anophelesgam      KIDINVRGIGFGLLEVIYQYDLNLVKFENRFKLDLEKQ------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      EDYNDYEGDYGDG-EKREEEDVPRSAIEWFDARS----------------
tr_Q9I932ComplementC4B_Cyprinu      QTYNYYEDYEQDE-ERNEEEDLPRSAIEWFDARS----------------
sp_P01028_CO4_HUMANComplementC      EDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNR--------------
sp_P01029_CO4_MOUSEComplementC      EDYED--YYDMPAADDPSVPLQPVTPLQLFEGRRSR--------------
tr_Q9I933ComplementC4A_Cyprinu      NETFDDYYNYEGDEDQKDE---PMSSIEWFDLRS----------------
tn_BAC82347ComplementC4_Triaki      YAEADKQLN-DSKTLPANA---PTGPLDWYDLRS----------------
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------------------------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      --------------------------------------------------
tn_AAQ74974ComplementC3_Ctenop      --------------------------------------------------
tr_Q9YIA7ComplementC3_S_Cyprin      --------------------------------------------------
tr_Q9YIB0ComplementC3_H1_Cypri      --------------------------------------------------
sp_P98093_CO3_ONCMYComplementC      --------------------------------------------------
tr_Q98TS6ComplementcomponentC3      --------------------------------------------------
tr_Q9PTY1ComplementcomponentC3      --------------------------------------------------
tr_Q9IBH1OrlaC3_1protein_Oryzi      --------------------------------------------------
tr_Q9IBH0OrlaC3_2protein_Oryzi      --------------------------------------------------
sp_Q01833_CO3_NAJNAComplementC      --------------------------------------------------
tr_Q91132Cobravenomfactorprecu      --------------------------------------------------
tr_Q91588ComplementcomponentC3      --------------------------------------------------
tr_Q90633ComplementC3precursor      --------------------------------------------------
sp_P01024_CO3_HUMANComplementC      --------------------------------------------------
tr_Q80XP1Complementcomponent3_      --------------------------------------------------
sp_P01026_CO3_RATComplementC3p      --------------------------------------------------
sp_P01027_CO3_MOUSEComplementC      --------------------------------------------------
sp_P12387_CO3_CAVPOComplementC      --------------------------------------------------
tr_Q9GKP1ComplementcomponentC3      --------------------------------------------------
sp_Q00685_CO3_LAMJAComplementC      GRLGWFDGKRRRR-------------------------------------
sp_P98094_CO3_EPTBUComplementC      --------------------------------------------------
sp_P01031_CO5_HUMANComplementC      --------------------------------------------------
tr_Q8AYN9ComplementcomponentC5      --------------------------------------------------
tr_Q969A4ComplementcomponentC3      PEEGQEGDEDYPDYDGELDARERSAFSSRSRIGGLLSSGR----------
tr_Q03626Alpha_1_inhibitorIIIp      --------------------------------------------------
tr_Q9PVU4Alpha_2_macroglobulin      --------------------------------------------------
tr_O44344ComplementcomponentC3      --------------------------------------------------
tr_Q8I7P1ComplementcomponentC3      NDAPKPTKAPKKKKNRPGKGKGRKRNRNKKCRRKNGRRCSGCKGRRCRKP
tr_O97019AsC3protein_Halocynth      --------------------------------------------------
tr_Q8WPD8ComplementcomponentC3      --------------------------------------------------
tr_Q8TDJ3CD109_Homosapiens_Hum      --------------------------------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      ASAAEGSRGDWPP-------------------------------------
tr_Q7Q7S6AgCP4019_Anophelesgam      --------------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      --------RHRRDTQQSRNSENDVEYEVCVSHSLT----RNLTGMSIADI
tr_Q9I932ComplementC4B_Cyprinu      --------RQKRDTTQN--TQDEVVYTVCVSHTQG----RNLSGMAIADI
sp_P01028_CO4_HUMANComplementC      --------RRREAPKVVEEQESRVHYTVCIWRNGK----VGLSGMAIADV
sp_P01029_CO4_MOUSEComplementC      --------RRREAPKVAEEQESRVQYTVCIWRNGK----LGLSGMAIADI
tr_Q9I933ComplementC4A_Cyprinu      --------RRKRQISEEPKKESSVIYTVCVGMKK-----KNTIGMVMVEI
tn_BAC82347ComplementC4_Triaki      --------RRKRDVP-DPTNRQTIYYEVCYWRDRNHEEIQFPSGMAIVDI
tr_Q9YIA5ComplementC3_Q2_Cypri      --------------AKH-GTIASYKLTMDFIYKS----DKTDATMTILDV
tr_Q9YIA9ComplementC3_H1_Cypri      --------------ANQ-GAIETYKITMDFYYKS----DKTDATMTILDI
tn_AAQ74974ComplementC3_Ctenop      --------------TKQEGALETYKLTMDFFYKS----DKTDATMTILDI
tr_Q9YIA7ComplementC3_S_Cyprin      --------------SNQEGAIETYKFTMDFYYKS----DKKDATMTILDI
tr_Q9YIB0ComplementC3_H1_Cypri      --------------EANQGAIETYKITMDFYYKS----DKTDATMTILDI
sp_P98093_CO3_ONCMYComplementC      --------------TSHEDAKESFMLTIEVLYKN----SERDATMSILDI
tr_Q98TS6ComplementcomponentC3      --------------MD--DDEMVYMLRIEILYKD----KDSDATMSILDI
tr_Q9PTY1ComplementcomponentC3      ----------------IDADESIFKLKIEVLYKD----KERDATMSILDI
tr_Q9IBH1OrlaC3_1protein_Oryzi      --------------AKNIGNQKVYKLQIEVLYKD----SNRDATMSILDI
tr_Q9IBH0OrlaC3_2protein_Oryzi      ---------------KNIGNQKVYKLQIEVLYKD----SDRDAAMSILDI
sp_Q01833_CO3_NAJNAComplementC      ------------NLKQAKGGKAALRLKICTRYL-----GEVDSTMTIIDI
tr_Q91132Cobravenomfactorprecu      ------------NAMG---AKGALMLKICTRYL-----GEVDSTMTIIDI
tr_Q91588ComplementcomponentC3      ------------ARPPD-GAKATVSIEACARHL-----KNVDATMSIIDI
tr_Q90633ComplementC3precursor      ------------GREVEGVIRSVKIT-ICTRFL-----DTVDATMSILDI
sp_P01024_CO3_HUMANComplementC      ------------TEKRPQDAKNTMILEICTRYR-----GDQDATMSILDI
tr_Q80XP1Complementcomponent3_      ------------TAKKPEEAKNTMFLEICTKYL-----GDVDATMSILDI
sp_P01026_CO3_RATComplementC3p      ------------TAKKPQDAKSSMILDICTRYL-----GDVDATMSILDI
sp_P01027_CO3_MOUSEComplementC      ------------TAKKPEEAKNTMFLEICTKYL-----GDVDATMSILDI
sp_P12387_CO3_CAVPOComplementC      ------------TVKKPQEAKSTMILGICTRYL-----GDQDATMSILDI
tr_Q9GKP1ComplementcomponentC3      ------------PVKKPQEAKSSMVLDICTRYL-----GNQDATMSILDI
sp_Q00685_CO3_LAMJAComplementC      -----------RDIGDEGGVEAVYRMNMCTRYKPRKEDLSSESGMTIIEV
sp_P98094_CO3_EPTBUComplementC      ----------QRRRQSINPEFNVYRFIGCFRYLR-----NQEPGMVVMDI
sp_P01031_CO5_HUMANComplementC      --------------YRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDI
tr_Q8AYN9ComplementcomponentC5      --------------DDPMLRS--QRIVACAKYKPPENEFETESGITVMEI
tr_Q969A4ComplementcomponentC3      ------SRSRIARQAEDDQSQHFYLVRVCTSYRG----QRGASNMAIMDI
tr_Q03626Alpha_1_inhibitorIIIp      ---------------------NSFQISLEISYTGS----RPASNMVIADV
tr_Q9PVU4Alpha_2_macroglobulin      -----------------------FFLNFTVKYGGP----QETTNMLIVDI
tr_O44344ComplementcomponentC3      ---------------VSGQNVKGLMITVCTSYN-----GDGTTHMIIVDV
tr_Q8I7P1ComplementcomponentC3      KPTTAAPQVTTRPPPEDGPVPNSVSIKICTRFKKAG----ASAGMSIIDV
tr_O97019AsC3protein_Halocynth      --------------VDEAQEEDMKVVKMTVSKN------GTKAQMSIIDV
tr_Q8WPD8ComplementcomponentC3      -----------VRVMNPGVQGKRIKITITVSKP-----LGPQSEATILYV
tr_Q8TDJ3CD109_Homosapiens_Hum      ---------------ENKDDLNHVDLNVCTSFS-----GPGRSGMALMEV
tr_Q8IZJ3Alpha_2macroglobulinf      -------ADDDDPAADQHHQEYKVMLEVCTRWLHAG-----SSNMAVLEV
tr_Q7Q7S6AgCP4019_Anophelesgam      -----------------NIGSDKMILNVCASFIP--MYLQSQSNMALIEV
                                                                                  :  :

tn_CAD66666ComplementC4_Oncorh      TLLSGFEAQTDDLDKLKNPDEQYISHYEVS------HGKVLLHFNEIEE-
tr_Q9I932ComplementC4B_Cyprinu      TLLSGFDAISTDLEKLKDLVDRYISHYELT------RGRVLLYFNEIEEG
sp_P01028_CO4_HUMANComplementC      TLLSGFHALRADLEKLTSLSDRYVSHFETE------GPHVLLYFDSVPTS
sp_P01029_CO4_MOUSEComplementC      TLLSGFHALRADLEKLTSLSDRYVSHFETD------GPHVLLYFDSVPTT
tr_Q9I933ComplementC4A_Cyprinu      SLLSGLIPNAKDLEHNVKGSERYIDHYEVH------HNKVFLYF-AKITD
tn_BAC82347ComplementC4_Triaki      LLLSGLKPELVHLDQLKNGADQYIDHYEVK------DGRVLLYLNTDRMQ
tr_Q9YIA5ComplementC3_Q2_Cypri      GLPTGFEVEESDLKQLSSGKERYIQKFEMNKVLSERGSLILYLDKVSHKE
tr_Q9YIA9ComplementC3_H1_Cypri      GIPTGFTVENRDLEELSRGKERYIQKFEMDKVLSERGSLILYLDKVLRKE
tn_AAQ74974ComplementC3_Ctenop      GIPTGFRVEGKDLEELSTGKERYIQKFEMDKLLSERGSLILYLDKVLRTE
tr_Q9YIA7ComplementC3_S_Cyprin      GIPTGFSVDSRDLQELSTGKERYIQKFEMDKVLSERGSLILYLEKVLHRE
tr_Q9YIB0ComplementC3_H1_Cypri      GIPTGFTVENRDLEELSRGKERYIQKFEMDKVLSERGSLILYLDKVLRKE
sp_P98093_CO3_ONCMYComplementC      GLLTGFIVDTDDLNQLSKGRERYIEKFEMDKVLSERGSLILYLDKVSHKL
tr_Q98TS6ComplementcomponentC3      GLLTGFTVNTKDLDQLSKGRARTIEKYEMDKVLSERGSLIIYLEKVSHTR
tr_Q9PTY1ComplementcomponentC3      GLLTGFTPNTNDLNLLSKGRARTLAKYEMNTLLSEKGSLIIYLDKVSHTR
tr_Q9IBH1OrlaC3_1protein_Oryzi      GLQTGFTPNLDDLKALSGGRFPLISKYEMNTALSERGSLIIYLDKISHTR
tr_Q9IBH0OrlaC3_2protein_Oryzi      GLQTGFTPNLDDLKALSGGRAPIISKYEMDTALSERGSLIIYLDKVSHTR
sp_Q01833_CO3_NAJNAComplementC      SMLTGFFPDAEDLKRLSNGVDRYISKFEIDNNMAQKGTVVIYLDKVSHSE
tr_Q91132Cobravenomfactorprecu      SMLTGFLPDAEDLTRLSKGVDRYISRYEVDNNMAQKVAVIIYLNKVSHSE
tr_Q91588ComplementcomponentC3      SMMTGFSPDTNSLDRLMKGVDKYISKYEVNKGANDKGTLILYLDKVSHIE
tr_Q90633ComplementC3precursor      SMLTAFSPDVQDLKSLSEGVERYISKFEIDHALSNRSNLIIYLDKVSHQV
sp_P01024_CO3_HUMANComplementC      SMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSE
tr_Q80XP1Complementcomponent3_      SMMTGFAPDTKDLELLASGVDRYISKYEMNKAFSNKNTLIIYLEKISHTE
sp_P01026_CO3_RATComplementC3p      SMMTGFIPDTNDLELLSSGVDRYISKYEMDKAFSNKNTLIIYLEKISHSE
sp_P01027_CO3_MOUSEComplementC      SMMTGFAPDTKDLELLASGVDRYISKYEMNKAFSNKNTLIIYLEKISHTE
sp_P12387_CO3_CAVPOComplementC      SMMTGFIPDTDDLKLLATGVDRYISKYEMNKDFS-KNTLIIYLDKVSHSE
tr_Q9GKP1ComplementcomponentC3      SMMTGFSPDTEDLKLLSTGVDRYISKYELNKALSNKNTLIIYLDKISHTL
sp_Q00685_CO3_LAMJAComplementC      NMLTGFIPDKNDLIQLKESVDKYISNYEITDS-----VLIIYWDKVPSTE
sp_P98094_CO3_EPTBUComplementC      SLPTGFEAKKKDLDDMKNLVDNYIVQYEIR-----PGRVFLYLDKVNKDE
sp_P01031_CO5_HUMANComplementC      SLPTGISANEEDLKALVEGVDQLFTDYQIK-----DGHVILQLNSIPSSD
tr_Q8AYN9ComplementcomponentC5      HLPTGVTAVQEDLDRYLNGLESRISNYEIN-----GDQVILQIDSIPSEE
tr_Q969A4ComplementcomponentC3      GMFSGFEPVKQDLEQLLNRAGKKAVQRYETTN-----RAVLLYFDEITSE
tr_Q03626Alpha_1_inhibitorIIIp      KMLSGFIPLKPTVKKLER-------LEHVSRTEVTTNNVLLYLDQVTNQT
tr_Q9PVU4Alpha_2_macroglobulin      KILSGFTADTSMLRTSFSSA--VLAQKYVERVDTKEDHVIVYLTEIPKHI
tr_O44344ComplementcomponentC3      GLYSGFKAVEEGLTGLKQVVNGSSLISSYEAS---SRSVIFYLDTIPSDE
tr_Q8I7P1ComplementcomponentC3      GILTGFSVKQESLVELQEKVKPGISKFEISDR-----HAILYIDEIPSDH
tr_O97019AsC3protein_Halocynth      VMLSGFEADKDSIAALNKDIAADGIFDRYELTN----NAVKFYLGSIGEK
tr_Q8WPD8ComplementcomponentC3      GFMSGYKAVDQTLEDLSIDENVAGVVDRYEVTN----HNVLFYLNRITSQ
tr_Q8TDJ3CD109_Homosapiens_Hum      NLLSGFMVPSEAISLSETVKKVEYDHGKLN-----------LYLDSVNET
tr_Q8IZJ3Alpha_2macroglobulinf      PLLSGFRADIESLEQLLLDKHMGMKRYEVAG-----RRVLFYFDEIPSRC
tr_Q7Q7S6AgCP4019_Anophelesgam      TLPSGYVVDRNPISEQTTVNPIKKIETRYG------GTSVVVYYDNMDDK
                                     : :.       :                                     

tn_CAD66666ComplementC4_Oncorh      RECVTFRAVQTVTIGLLQPAPATFYVYYEPDRKCTTFYAAPKRSKMVSTL
tr_Q9I932ComplementC4B_Cyprinu      KACIAFGAKQSVAIGLVQPAPATFYDYYEPDRRCSVLYSAPKRSKAVSVL
sp_P01028_CO4_HUMANComplementC      RECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATL
sp_P01029_CO4_MOUSEComplementC      RECVGFGASQEVVVGLVQPSSAVLYDYYSPDHKCSVFYAAPTKSQLLATL
tr_Q9I933ComplementC4A_Cyprinu      TECLQFGAEQVVPMGLVQPASAVIYDYYSPEKRCGIFYTAPHKSPMISKL
tn_BAC82347ComplementC4_Triaki      KECIEFSAKQIVRMGLVQPATATLYDFYNPSVRCTLTYSAPKQNVMITKL
tr_Q9YIA5ComplementC3_Q2_Cypri      KKVISFRMHQLYNVGLLQPAAVTIYEYYSPDARCTMFYHPERTDAAIYRL
tr_Q9YIA9ComplementC3_H1_Cypri      PQRLAFRMHKMLNVGVLQPAAVTIYEYYSPNARCTKFFHPERADGAISRL
tn_AAQ74974ComplementC3_Ctenop      PQRISFRMHKMLDVGELQPAAVTIYEYYSPNARCTKFFHPKRKDAAIYRL
tr_Q9YIA7ComplementC3_S_Cyprin      KERIAFRMHKIQNVGLLQPAAVTIYEYYSPDARCTKFFHPEREDGALYRL
tr_Q9YIB0ComplementC3_H1_Cypri      PQRLAFRMHKMLNVGVLQPAAVTIYEYYSPNARCTKFFHPERADGAISRL
sp_P98093_CO3_ONCMYComplementC      EDRISFKIHRVQEVGVLQPAAVSVYEYYN-QKRCVKFYHPQREGGTLSRL
tr_Q98TS6ComplementcomponentC3      PEEITFRVHQTLKVGVLQPAAVSVYEYYD-QTRCVKFYHPERKAGELMRL
tr_Q9PTY1ComplementcomponentC3      PEEITFRVHQKMKVGVLQPAAVSVYEYYD-QTQCVQFYHPQRKAGQLLRL
tr_Q9IBH1OrlaC3_1protein_Oryzi      PEEISFRVQQTMEVGVLQPAAVSVYEYYEQTP-CVKFYHPEREGGQLLKL
tr_Q9IBH0OrlaC3_2protein_Oryzi      PEEISFRVQQTMEVGVLQPAAVSVYEYYEQTP-CVKFYHPEREGGQLLQL
sp_Q01833_CO3_NAJNAComplementC      DECLHFKIHKHFEVGFIQPGSVKVYSYYNLDEQCTKFYHPDKETGLLNKI
tr_Q91132Cobravenomfactorprecu      DECLHFKILKHFEVGFIQPGSVKVYSYYNLDEKCTKFYHPDKGTGLLNKI
tr_Q91588ComplementcomponentC3      EECVKFYAHQYFEVGFIQPASVTVYDYYTPDNRCTKFYHVEEGSALLGRI
tr_Q90633ComplementC3precursor      EECIAFRAHQHFQVGLIQPASVIVYSYYKIDDRCTRFYHPDKAGGQLRKI
sp_P01024_CO3_HUMANComplementC      DDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKL
tr_Q80XP1Complementcomponent3_      EDCLTFKVHQYFNVGLIQPGSVKVYSYYNLEESCTRFYHPEKDDGMLSKL
sp_P01026_CO3_RATComplementC3p      EDCLSFKVHQFFNVGLIQPGSVKVYSYYNLEESCTRFYHPEKDDGMLSKL
sp_P01027_CO3_MOUSEComplementC      EDCLTFKVHQYFNVGLIQPGSVKVYSYYNLEESCTRFYHPEKDDGMLSKL
sp_P12387_CO3_CAVPOComplementC      EECLSFKIHQFFNVGLIQPGSVKVYSYYNLDETCTQFYHPEKEDGMLNKL
tr_Q9GKP1ComplementcomponentC3      EDCISFKVHQYFNVGLIQPGSVKVYSYYNLDESCTRFYHPEKEDGMLNKL
sp_Q00685_CO3_LAMJAComplementC      DYCFAFKIKQMLRSDMIQPVTASVYDYYSPADKCTRLYNLPGGYVELSPL
sp_P98094_CO3_EPTBUComplementC      KNCVGFRLNQVFESNLVLPVTATVFEYYEPDFRCSKSYH-PKMEVNPDAS
sp_P01031_CO5_HUMANComplementC      FLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNI--KIQKV
tr_Q8AYN9ComplementcomponentC5      LYCVGFRIQEEFETGMTRASVFQVYQFSNPEHKCMKFYHKQSR--KLLRL
tr_Q969A4ComplementcomponentC3      EICVSIRMKRVMLVGAVQPVPVSVYDYYQPDEACTTFYHPGQGSPLLATL
tr_Q03626Alpha_1_inhibitorIIIp      -LSFSFIIQQDIPVKNLQPAIVKVYDYYETDEVAFAEYSSPCSSDKQNV-
tr_Q9PVU4Alpha_2_macroglobulin      SMNYKMKMKQVLPVKNLKPAVVKVYDYYQTSKILF---------------
tr_O44344ComplementcomponentC3      DLCFTFSAESDVVVGNVQAAAVHVYDYYDPEKSCTIFYKPGDGSALLSTL
tr_Q8I7P1ComplementcomponentC3      ELCFNLELTRDFSVGIVQPVPVTVYDYYEPDNKCTKFYGPEPNSLLNLAT
tr_O97019AsC3protein_Halocynth      EIKFAFKIKQVSVVSKIQPASVIVYDYYEPDIRCTKFYTVGDPNLKLRTI
tr_Q8WPD8ComplementcomponentC3      SMNISFEMRQMVLVRKPQPGKINIYEYYEPVVHCGQFYSLPDTTPDLQTS
tr_Q8TDJ3CD109_Homosapiens_Hum      QFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLC
tr_Q8IZJ3Alpha_2macroglobulinf      LTCVRFRALRECVVGRTSALPVSVYDYYEPAFEATRFYNVSTHSPLAREL
tr_Q7Q7S6AgCP4019_Anophelesgam      KHCFTVSAHRQQMPTLRRPAYVVVYDYYDTNINAIKMYQLEDLSACEISG
                                         .                 .  :                       

tn_CAD66666ComplementC4_Oncorh      CS-------GDVCQCSERPCHKEK-------DTFGP-LKLEKKDRFEHAC
tr_Q9I932ComplementC4B_Cyprinu      CS-------DDVCQCAERGCFTEK-------KTID--MEITKKKRFEYAC
sp_P01028_CO4_HUMANComplementC      CS-------AEVCQCAEGKCPRQR-------RALERGLQDEDGYRMKFAC
sp_P01029_CO4_MOUSEComplementC      CS-------GDVCQCAEGKCPRLL-------RSLERRVEDKDGYRMRFAC
tr_Q9I933ComplementC4A_Cyprinu      CN-------GDVCTCAEGGCPRNK-------VTFSK--DIKDKTRSRYAC
tn_BAC82347ComplementC4_Triaki      CD-------GEVCMCAEGACPHIN-------HVLSN--EVNGSARIDFAC
tr_Q9YIA5ComplementC3_Q2_Cypri      CK-------GDLCLCAEENCS----------FQKK--NNVRDEERLNRVC
tr_Q9YIA9ComplementC3_H1_Cypri      CK-------GDLCQCAEENCS----------YQKK--NHIGDEERFNRAC
tn_AAQ74974ComplementC3_Ctenop      CK-------GDLCQCAEEKCS----------LQKK--DDVQDEERLVKAC
tr_Q9YIA7ComplementC3_S_Cyprin      CK-------GDMCQCAEENCS----------YQKK--NHVEDDERFNKAC
tr_Q9YIB0ComplementC3_H1_Cypri      CK-------GDLCQCAEENCS----------YQKK--NHIGDEERFNRAC
sp_P98093_CO3_ONCMYComplementC      CL-------GDVCTCAEESCS----------MQKK--GEP-DVQRIDKAC
tr_Q98TS6ComplementcomponentC3      CR-------NHECTCAEENCS----------MQKK--EQVSNDQRTAKVC
tr_Q9PTY1ComplementcomponentC3      CR-------NEECTCAEENCS----------MQKK--GKISNDQRIEKSC
tr_Q9IBH1OrlaC3_1protein_Oryzi      CK-------DDECTCAEENCS----------MQKN--GQISNDERTSKIC
tr_Q9IBH0OrlaC3_2protein_Oryzi      CR-------DDECTCAEENCS----------MQKN--GQISNDERTSKIC
sp_Q01833_CO3_NAJNAComplementC      CH-------GNICRCAEETCS----------LLNQQK-KIDLQLRIQKAC
tr_Q91132Cobravenomfactorprecu      CI-------GNVCRCAGETCS----------SLNHQE-RIDVPLQIEKAC
tr_Q91588ComplementcomponentC3      CQ-------GDLCRCAEENCF----------MQQQIEGKITAEMRINMGC
tr_Q90633ComplementC3precursor      CH-------GEVC-CAEENCF----------IRVKKDNPITVNERIDLAC
sp_P01024_CO3_HUMANComplementC      CR-------DELCRCAEENCF----------IQKSDD-KVTLEERLDKAC
tr_Q80XP1Complementcomponent3_      CH-------SEMCRCAEENCF----------MQQSQE-KINLNVRLDKAC
sp_P01026_CO3_RATComplementC3p      CH-------NEMCRCAEENCF----------MHQSQD-QVSLNERLDKAC
sp_P01027_CO3_MOUSEComplementC      CH-------SEMCRCAEENCF----------MQQSQE-KINLNVRLDKAC
sp_P12387_CO3_CAVPOComplementC      CH-------KDLCRCAEENCF----------IQLP--EKITLDERLEKAC
tr_Q9GKP1ComplementcomponentC3      CH-------KEMCRCAEENCF----------MHHDEE-EVTLDDRLERAC
sp_Q00685_CO3_LAMJAComplementC      CQ-------NDLCQCVEVSCPA---------KKPKFDTSITVLHRQEAAC
sp_P98094_CO3_EPTBUComplementC      CH-------GNICNCLQRHCVE----------LKGMADEDRNADRNGNAC
sp_P01031_CO5_HUMANComplementC      CE-------GAACKCVEADCGQ---------MQEELDLTISAETRKQTAC
tr_Q8AYN9ComplementcomponentC5      CE-------GDQCQCMAAECCN---------FKSTIDPKITAVQRKNDMC
tr_Q969A4ComplementcomponentC3      CD-------GSQCVCAEGKCP--------KETSPKKLRELTQRDLEEKAC
tr_Q03626Alpha_1_inhibitorIIIp      --------------------------------------------------
tr_Q9PVU4Alpha_2_macroglobulin      --------------------------------------------------
tr_O44344ComplementcomponentC3      CS-------ENECICSGGSLEYCN--------IDPCPGPYTRIDLEGTAC
tr_Q8I7P1ComplementcomponentC3      CE-------HDTCKCALDKCS-------------SCKTSDDSAVVKGLFC
tr_O97019AsC3protein_Halocynth      CEDG-----GVLCKCAEGDCPVCR-----SQNDQLTNTQCSSHGNHEQIC
tr_Q8WPD8ComplementcomponentC3      NCETGANNDDNLCRCAEGGCPTCRTR--DDTLFKLHVLEVEVGARCGTCT
tr_Q8TDJ3CD109_Homosapiens_Hum      SD-------VQGCRPCEDGASG----------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      CA-------GPACNEVERAPARGPGWFP--GESGPAVAPEEGAAIARCGC
tr_Q7Q7S6AgCP4019_Anophelesgam      EVD-----CSEVCKTKGQV-------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      YSP---------------TVDYGFIVQVISMSVKSN--FELYTTNVTQVL
tr_Q9I932ComplementC4B_Cyprinu      FHT---------------NIEYAFEVIVNSVTEESN--FMLYSATVTVVL
sp_P01028_CO4_HUMANComplementC      YYP---------------RVEYGFQVKVLREDSRAA--FRLFETKITQVL
sp_P01029_CO4_MOUSEComplementC      YYP---------------RVEYGFTVKVLREDGRAA--FRLFESKITQVL
tr_Q9I933ComplementC4A_Cyprinu      YSP---------------GVDYAYVIKVLNSSTDHV--FMYYTTLITDVL
tn_BAC82347ComplementC4_Triaki      YSP---------------IVDYAYTVRVLNISSAGS--FDNYQVSIADRL
tr_Q9YIA5ComplementC3_Q2_Cypri      EPG----------------MDYIYKVTVVGMDLKQD--SDIYDMKVELVL
tr_Q9YIA9ComplementC3_H1_Cypri      EAG----------------MDYVYKVKVVGMDLKQD--ADIYDLEVEQVL
tn_AAQ74974ComplementC3_Ctenop      EAG----------------MDYVYKVTVVGMDLAHD--SDIYHLKVDQVL
tr_Q9YIA7ComplementC3_S_Cyprin      EAGMD----------------YVYKVKVVGMDLKKD--SDIYEMKVEQVL
tr_Q9YIB0ComplementC3_H1_Cypri      EAG----------------MDYVYKVKVVGMDLQQD--ADIYDLEVEQVL
sp_P98093_CO3_ONCMYComplementC      GAGLD----------------YVYKATVVDSKLTTH--TDTYTVKIDLVI
tr_Q98TS6ComplementcomponentC3      ETELN------------NKIDFAYRVGLEEFTDGLS--TDIYKVRVLQVI
tr_Q9PTY1ComplementcomponentC3      ETTPT------------SKIDFVYKVRLEEFTDGGS--TDIYTMRILEGI
tr_Q9IBH1OrlaC3_1protein_Oryzi      ESTES------------SKIEYAYKVLVEDVVQKPS--IDIYAMRVQDSI
tr_Q9IBH0OrlaC3_2protein_Oryzi      ESTES------------SKIEYAYKVLVEDVVQKPS--IDIYAMRVQDSI
sp_Q01833_CO3_NAJNAComplementC      AQN----------------VDYVYKTKLLRIEEKDG--NDIYFMDVLEVI
tr_Q91132Cobravenomfactorprecu      ETN----------------VDYVYKTKLLRIEEQDG--NDIYVMDVLEVI
tr_Q91588ComplementcomponentC3      APG----------------VDFVYKATLTEVQPSDN--FDNYVMTIKKVI
tr_Q90633ComplementC3precursor      KPG----------------VDYVYKVKVVATEETPS--HDNYIMSILTVI
sp_P01024_CO3_HUMANComplementC      EPG----------------VDYVYKTRLVKVQLSND--FDEYIMAIEQTI
tr_Q80XP1Complementcomponent3_      EPG----------------VDYVYKTELTNIELLDD--FDEYTMTIQQVI
sp_P01026_CO3_RATComplementC3p      EPG----------------VDYVYKTKLTTIELSDD--FDEYIMTIEQVI
sp_P01027_CO3_MOUSEComplementC      EPG----------------VDYVYKTELTNIKLLDD--FDEYTMTIQQVI
sp_P12387_CO3_CAVPOComplementC      EPG----------------VDYVYKTKLLKMELSDD--FDEYIMTIEQVI
tr_Q9GKP1ComplementcomponentC3      EPG----------------VDYVYKTRLLKKELSDD--FDDYIMVIEQII
sp_Q00685_CO3_LAMJAComplementC      VAG----------------IDYAYVGIVDNRTEVGS--FVYYTVNIQTVI
sp_P98094_CO3_EPTBUComplementC      RAEY------------------VFIIGVTKVTKTAS--YININAALKTVL
sp_P01031_CO5_HUMANComplementC      KPE----------------IAYAYKVSITSITVENV--FVKYKATLLDIY
tr_Q8AYN9ComplementcomponentC5      KES----------------MNYAFKVLIESSEAGGD--FVTYKAKVKAVL
tr_Q969A4ComplementcomponentC3      -----------------NDLDYAFRVIVMEVRQEGS--FDRISMIVESPI
tr_Q03626Alpha_1_inhibitorIIIp      --------------------------------------------------
tr_Q9PVU4Alpha_2_macroglobulin      --------------------------------------------------
tr_O44344ComplementcomponentC3      ASHS----------------SYALKIRIDEVEIKEG--FRICKFTVLNPI
tr_Q8I7P1ComplementcomponentC3      -----------------TTYDYAFKGKLLIIDEEDQ--WLHLTFEVVEVY
tr_O97019AsC3protein_Halocynth      SDMCEDNIGCYNLHVETCKRDYVYIIKVESVEETEGSGYKIFKARIVEVI
tr_Q8WPD8ComplementcomponentC3      QNRCYN--------HRDEGCSAKYVYKVRVIGVREDSVFVNLDAVIEDVY
tr_Q8TDJ3CD109_Homosapiens_Hum      -------------------------------SHHHSSVIFIFCFKLLYFM
tr_Q8IZJ3Alpha_2macroglobulinf      DHDCG--------------AQGNPVCGSDGVVYASACRLREAACRQAAPL
tr_Q7Q7S6AgCP4019_Anophelesgam      --------------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      RATG--DVKLEESKVRVLAK--------------------RLQC-KGQLE
tr_Q9I932ComplementC4B_Cyprinu      RYTG--DLSVSADSTRVFAK--------------------RKHC-KSDLK
sp_P01028_CO4_HUMANComplementC      HFTK--DVKAAANQMRNFLV--------------------RASC-RLRLE
sp_P01029_CO4_MOUSEComplementC      HFRK--DTMASIGQTRNFLS--------------------RASC-RLRLE
tr_Q9I933ComplementC4A_Cyprinu      QTGL-LDSGIQKHATRQMIL--------------------RLSCDELELK
tn_BAC82347ComplementC4_Triaki      KMSN-KDDDVKIGEVRHFLS--------------------QRSC-KFQLK
tr_Q9YIA5ComplementC3_Q2_Cypri      KEG--TDEDAEGKVRQFLAR--------------------PSCREHLGLV
tr_Q9YIA9ComplementC3_H1_Cypri      KEG--TDVDVEGKRRPFLAR--------------------PTCRNHLGLV
tn_AAQ74974ComplementC3_Ctenop      KEG--TDEDVEGRVRLFLAR--------------------PSCREDLGLV
tr_Q9YIA7ComplementC3_S_Cyprin      KEG--TDEDVEGTVRTFLAR--------------------PSCREHLGLV
tr_Q9YIB0ComplementC3_H1_Cypri      KEG--TDVDVEGKRRPFLAR--------------------PTCRNHLGLV
sp_P98093_CO3_ONCMYComplementC      KPG--TDEGVEGKNRDFMGL--------------------AYCREALGLM
tr_Q98TS6ComplementcomponentC3      KEGS-KDVGPLNKERTLLSY--------------------PHCRDPLDLR
tr_Q9PTY1ComplementcomponentC3      KEGS-YDVAPQGKLRTFLSY--------------------QHCRESLDLG
tr_Q9IBH1OrlaC3_1protein_Oryzi      KEGS-TDVGPRGKLRPFLSY--------------------PHCRDALNLQ
tr_Q9IBH0OrlaC3_2protein_Oryzi      KEGS-TDVGPMGKLRPFLSY--------------------PHCRDALNLL
sp_Q01833_CO3_NAJNAComplementC      KGG--TDRNAQAKARQYVSQ--------------------RKCQEALNLK
tr_Q91132Cobravenomfactorprecu      KQG--TDENPRAKTHQYISQ--------------------RKCQEALNLK
tr_Q91588ComplementcomponentC3      KQG--TDEDPEDKTRNFISH--------------------IKCRKALNMQ
tr_Q90633ComplementC3precursor      KMG--TDENPGGSNRTFVSH--------------------KQCRDALSLQ
sp_P01024_CO3_HUMANComplementC      KSG--SDEVQVGQQRTFISP--------------------IKCREALKLE
tr_Q80XP1Complementcomponent3_      KSG--SDEVQAGQQRKFISH--------------------IKCRNALKLQ
sp_P01026_CO3_RATComplementC3p      KSG--SDEVQAGQERRFISH--------------------VKCRNALKLQ
sp_P01027_CO3_MOUSEComplementC      KSG--SDEVQAGQQRKFISH--------------------IKCRNALKLQ
sp_P12387_CO3_CAVPOComplementC      KSG--SDEVQAGKERRFISH--------------------IKCRDALHLK
tr_Q9GKP1ComplementcomponentC3      KSG--SDEVQVGQERRFISH--------------------IKCREALKLK
sp_Q00685_CO3_LAMJAComplementC      KSGQ-DQAIQPKATRLFIVT--------------------RSCDGRLGME
sp_P98094_CO3_EPTBUComplementC      KKGM-DQAINVGARRSFVIP--------------------MHCGKNLNVS
sp_P01031_CO5_HUMANComplementC      KTGE-AVAEK-DSEITFIKK--------------------VTCTN-AELV
tr_Q8AYN9ComplementcomponentC5      MKGQ-TDDLKTDSEIDLVKK--------------------ATCSS-TNFE
tr_Q969A4ComplementcomponentC3      KKG--LDDVFDGEERVFWK---------------------RKTCSGLQLV
tr_Q03626Alpha_1_inhibitorIIIp      --------------------------------------------------
tr_Q9PVU4Alpha_2_macroglobulin      --------------------------------------------------
tr_O44344ComplementcomponentC3      KTGD-EDVPHQAQRQLFINEG-------------------CDCPKVKGRN
tr_Q8I7P1ComplementcomponentC3      KESVTKKITKKTARIVYSKK-------------------ISCDCPVFAGK
tr_O97019AsC3protein_Halocynth      RSTS-KHIDPKDDVTSFRIREDCYAESCKDPRFEEIARKKNNAVEAKFIE
tr_Q8WPD8ComplementcomponentC3      RSG--SDNVQNGTVRTFVIRNDCHASCRDTDEDLRLLRNNIPAKDTRLFK
tr_Q8TDJ3CD109_Homosapiens_Hum      ELWL----------------------------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      EPAPPSCCALEQRLPASSSS---------------TYGDDLASVAPGPLQ
tr_Q7Q7S6AgCP4019_Anophelesgam      --------------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      TGKTYLIMGKD---GSTTDSNG----------------------QMQYLL
tr_Q9I932ComplementC4B_Cyprinu      EGKTYLIMGND---GPTKDLNG----------------------NMQYLL
sp_P01028_CO4_HUMANComplementC      PGKEYLIMGLD---GATYDLEG----------------------HPQYLL
sp_P01029_CO4_MOUSEComplementC      PNKEYLIMGMD---GETSDNKG----------------------DPQYLL
tr_Q9I933ComplementC4A_Cyprinu      KEVHYLIMGQNDAISVLNNDGQ----------------------HFRYVL
tn_BAC82347ComplementC4_Triaki      EGDEYLVMGQD---GTTSDTSR----------------------KMQYLL
tr_Q9YIA5ComplementC3_Q2_Cypri      EGKSYLIMGRSDDLP--ELGGS-----------------------LQYVF
tr_Q9YIA9ComplementC3_H1_Cypri      EGKSYLIMGRSVDLP--DLGGS-----------------------LQYIF
tn_AAQ74974ComplementC3_Ctenop      KGKSYLIMGKSTDLP--KLGGS-----------------------LQYIL
tr_Q9YIA7ComplementC3_S_Cyprin      KGKSYLIMGKSVDLP--KLGG-----------------------SLQYIM
tr_Q9YIB0ComplementC3_H1_Cypri      KDKSYLIMGRSVDLP--DLGGS-----------------------LQYIF
sp_P98093_CO3_ONCMYComplementC      QGKTYMIMGKSEDLHRVEDKGLL---------------------QYKYVL
tr_Q98TS6ComplementcomponentC3      TGNNYLIMGASTDIYRDDQ--AQ---------------------SHQYVL
tr_Q9PTY1ComplementcomponentC3      KGKMYLIMGTSKDIHRDDQNES-----------------------YHYVL
tr_Q9IBH1OrlaC3_1protein_Oryzi      KGKTYLIMGSSRDIHKDEKQLT-----------------------YQYVL
tr_Q9IBH0OrlaC3_2protein_Oryzi      KGKTYLIMGSSRDIHRDEKKQT-----------------------YQYVL
sp_Q01833_CO3_NAJNAComplementC      LDNDYLIWGLSSDLWPMKDDIS-------------------------YLI
tr_Q91132Cobravenomfactorprecu      VNDDYLIWGSRSDLLPTKDKIS-------------------------YII
tr_Q91588ComplementcomponentC3      LNRDYLIWGVTGDLWRQPDGYS-------------------------YII
tr_Q90633ComplementC3precursor      KGQDYLVWGLASDLWVTGSRFS-------------------------YLI
sp_P01024_CO3_HUMANComplementC      EKKHYLMWGLSSDFWGEKPNLS-------------------------YII
tr_Q80XP1Complementcomponent3_      KGKKYLMWGLSSDLWGEKPNTS-------------------------YII
sp_P01026_CO3_RATComplementC3p      KGKQYLMWGLSSDLWGEKPNTS-------------------------YII
sp_P01027_CO3_MOUSEComplementC      KGKKYLMWGLSSDLWGEKPNTS-------------------------YII
sp_P12387_CO3_CAVPOComplementC      EGKHYLMWGLSSDLWGERPNMS-------------------------YII
tr_Q9GKP1ComplementcomponentC3      EGGHYLVWGVSSDLWGEKPNIS-------------------------YII
sp_Q00685_CO3_LAMJAComplementC      TPRQYLLMGRKGETKDRNDRFQ-------------------------YVL
sp_P98094_CO3_EPTBUComplementC      PGDIYLVMGMHNAHWRNSDRTQ-------------------------YVL
sp_P01031_CO5_HUMANComplementC      KGRQYLIMGKEALQIKYNFSFR-----------------------YIYPL
tr_Q8AYN9ComplementcomponentC5      VGKQYLIMTAESIKIRMNRGYK-----------------------YKFPL
tr_Q969A4ComplementcomponentC3      EGTTYLLMGKDGTKYTDEQGFD----------------------SFRYVI
tr_Q03626Alpha_1_inhibitorIIIp      --------------------------------------------------
tr_Q9PVU4Alpha_2_macroglobulin      --------------------------------------------------
tr_O44344ComplementcomponentC3      IGGTFLLVGQKSLKYTTEQGEE----------------------RYRYVY
tr_Q8I7P1ComplementcomponentC3      IDRHFLIMGKDVGLRGSSKVV----------------------------L
tr_O97019AsC3protein_Halocynth      EGRHLLVYGSNPTVTEAKNEPVQ----------------------YIYEL
tr_Q8WPD8ComplementcomponentC3      EGRVLLITGSLIERRQNRNRLLQTVYQVDEQTTAERLVTDVACARAKSVL
tr_Q8TDJ3CD109_Homosapiens_Hum      --------------------------------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      QDVKLNGAGLEVEDSDPEPEGEAEDRVTAG------PRPPVSSGNLESST
tr_Q7Q7S6AgCP4019_Anophelesgam      --------------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      ESKTWIEQVPNEKKCQGSKNRPTCKKFKDFVSEYMLNGCTQ---------
tr_Q9I932ComplementC4B_Cyprinu      DSKTWVEEKLSPSTCRASVNKGFCKELKDFVKEYQVNGCNM---------
sp_P01028_CO4_HUMANComplementC      DSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV---------
sp_P01029_CO4_MOUSEComplementC      DSNTWIEEMPSEQMCKSTRHRAACFQLKDFLMEFSSRGCQV---------
tr_Q9I933ComplementC4A_Cyprinu      NNDMWIEKMPEEKNCKATKNRAACHLLNEFIKQHPITRCDI---------
tn_BAC82347ComplementC4_Triaki      DVKSWVEAIPPEDICELRKYRSSCRNLRNPMTARVDHGCP----------
tr_Q9YIA5ComplementC3_Q2_Cypri      GEQTWVEYWPTREESQTREHRERYIGISELQN-SLRYGCTL---------
tr_Q9YIA9ComplementC3_H1_Cypri      GEQTWIEYWPTRKESQTQEHRDRYIGISDLQNSLLKEGCAT---------
tn_AAQ74974ComplementC3_Ctenop      GEKNWVEYWPTREESQMKKYRDQYIGITELENSLLKERMLLHNYYKHLVI
tr_Q9YIA7ComplementC3_S_Cyprin      GEQTWVEYWPTREESQTREHRDRYIGISDLENSLRKEGCAT---------
tr_Q9YIB0ComplementC3_H1_Cypri      GEQTWIEYWPTRQESQTREHRDRYIGISDLQNSLLKEGCAT---------
sp_P98093_CO3_ONCMYComplementC      GEQTWIEYWPSQQECTSRDYREVCLGIDEFINQITTFGCPV---------
tr_Q98TS6ComplementcomponentC3      GERTWIEYWPTDKQCQTEEYRRTCLGMAEMVEQYRVFGCNQ---------
tr_Q9PTY1ComplementcomponentC3      GERTWIEYWPTEAECQTEEHRPTCLGLQQMVQQYLLFGCQQ---------
tr_Q9IBH1OrlaC3_1protein_Oryzi      GERTWIEYWPTAEECQGDEHRATCLGLDEMLEQFRVFACQQ---------
tr_Q9IBH0OrlaC3_2protein_Oryzi      GERTWIEYWPTAEECQGDEHRDTCLGLDEMLEQYRVFACQQ---------
sp_Q01833_CO3_NAJNAComplementC      TKNTWIERWPNEDECQDEEFQNLCDDFAQLSNTLTIFGCPT---------
tr_Q91132Cobravenomfactorprecu      TKNTWIERWPHEDECQEEEFQKLCDDFAQFSYTLTEFGCPT---------
tr_Q91588ComplementcomponentC3      GKDTWMEWWPNERECQQRENQDLCDDFETVSDNLEIVGCPN---------
tr_Q90633ComplementC3precursor      SKDTWLEAWPLEESCQDADLQPLCQDFTEFSDNLVLFGCPT---------
sp_P01024_CO3_HUMANComplementC      GKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN---------
tr_Q80XP1Complementcomponent3_      GKDTWVEHWPEAEECQDQKYQKQCEELGAFTESMVVYGCPN---------
sp_P01026_CO3_RATComplementC3p      GKDTWVEHWPEAEERQDQKNQKQCEDLGAFTETMVVFGCPN---------
sp_P01027_CO3_MOUSEComplementC      GKDTWVEHWPEAEECQDQKYQKQCEELGAFTESMVVYGCPN---------
sp_P12387_CO3_CAVPOComplementC      GKDTWVEAWPEAEECQDEENQQQCQDLGTFTENMVVFGCPN---------
tr_Q9GKP1ComplementcomponentC3      GKDTWVELWPDGDVCQDEENQKQCQDLANFSENMVVFGCPN---------
sp_Q00685_CO3_LAMJAComplementC      DASSWVEQWPVDEKCNQPNVQTFCAIKREYEFSMQIQGCSS---------
sp_P98094_CO3_EPTBUComplementC      TSDTWFEKFPLESVCRLPSPPASCQVSENFKGCSLKG-------------
sp_P01031_CO5_HUMANComplementC      DSLTWIEYWPRDTTCS--SCQAFLANLDEFAEDIFLNGC-----------
tr_Q8AYN9ComplementcomponentC5      DSRAWVDWWPLDTDCRDDACIQYANVLGEFESDFVLFGCED---------
tr_Q969A4ComplementcomponentC3      TEQSFVAEWPTGAKAERKKFKRVADKFQQLADKIFLQGCTT---------
tr_Q03626Alpha_1_inhibitorIIIp      --------------------------------------------------
tr_Q9PVU4Alpha_2_macroglobulin      --------------------------------------------------
tr_O44344ComplementcomponentC3      GPTSKLEFWPATRKARNAAVFDKLVAFEAQMAPASACSNEN---------
tr_Q8I7P1ComplementcomponentC3      GHNVFVKEWPMN---------DPVDFFKKFVRLLRKDGC-----------
tr_O97019AsC3protein_Halocynth      DDNARLEIVPSGEKCSPEILECAPNDIRCNKKKAKLDKITKLCKINSTLI
tr_Q8WPD8ComplementcomponentC3      VRCAGNRPPRQSKCVKSRELNAICENMKRLKESLNDIGCD----------
tr_Q8TDJ3CD109_Homosapiens_Hum      --------------------------------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      QSASPFHRWGQTPAPQRHSGRVVGAHRPGLLSPVFVYSPAFQSGGEEGLW
tr_Q7Q7S6AgCP4019_Anophelesgam      --------------------------------------------------
                                                                                      

tn_CAD66666ComplementC4_Oncorh      -----------------------------
tr_Q9I932ComplementC4B_Cyprinu      -----------------------------
sp_P01028_CO4_HUMANComplementC      -----------------------------
sp_P01029_CO4_MOUSEComplementC      -----------------------------
tr_Q9I933ComplementC4A_Cyprinu      -----------------------------
tn_BAC82347ComplementC4_Triaki      -----------------------------
tr_Q9YIA5ComplementC3_Q2_Cypri      -----------------------------
tr_Q9YIA9ComplementC3_H1_Cypri      -----------------------------
tn_AAQ74974ComplementC3_Ctenop      TEKLNIPCKLSVNLHNIRLGQNNLLITEN
tr_Q9YIA7ComplementC3_S_Cyprin      -----------------------------
tr_Q9YIB0ComplementC3_H1_Cypri      -----------------------------
sp_P98093_CO3_ONCMYComplementC      -----------------------------
tr_Q98TS6ComplementcomponentC3      -----------------------------
tr_Q9PTY1ComplementcomponentC3      -----------------------------
tr_Q9IBH1OrlaC3_1protein_Oryzi      -----------------------------
tr_Q9IBH0OrlaC3_2protein_Oryzi      -----------------------------
sp_Q01833_CO3_NAJNAComplementC      -----------------------------
tr_Q91132Cobravenomfactorprecu      -----------------------------
tr_Q91588ComplementcomponentC3      -----------------------------
tr_Q90633ComplementC3precursor      -----------------------------
sp_P01024_CO3_HUMANComplementC      -----------------------------
tr_Q80XP1Complementcomponent3_      -----------------------------
sp_P01026_CO3_RATComplementC3p      -----------------------------
sp_P01027_CO3_MOUSEComplementC      -----------------------------
sp_P12387_CO3_CAVPOComplementC      -----------------------------
tr_Q9GKP1ComplementcomponentC3      -----------------------------
sp_Q00685_CO3_LAMJAComplementC      -----------------------------
sp_P98094_CO3_EPTBUComplementC      -----------------------------
sp_P01031_CO5_HUMANComplementC      -----------------------------
tr_Q8AYN9ComplementcomponentC5      -----------------------------
tr_Q969A4ComplementcomponentC3      -----------------------------
tr_Q03626Alpha_1_inhibitorIIIp      -----------------------------
tr_Q9PVU4Alpha_2_macroglobulin      -----------------------------
tr_O44344ComplementcomponentC3      -----------------------------
tr_Q8I7P1ComplementcomponentC3      -----------------------------
tr_O97019AsC3protein_Halocynth      EAHLEGCDV--------------------
tr_Q8WPD8ComplementcomponentC3      -----------------------------
tr_Q8TDJ3CD109_Homosapiens_Hum      -----------------------------
tr_Q8IZJ3Alpha_2macroglobulinf      MSNTCTLR---------------------
tr_Q7Q7S6AgCP4019_Anophelesgam      -----------------------------