;; saved by seaview on Tue Oct 21 13:54:52 2003
;; saved by seaview on Fri Sep  5 10:25:33 2003
;; saved by seaview on Fri Aug 29 06:42:24 2003
;; saved by seaview on Fri Aug 29 06:13:33 2003
;
pdb_1EWk
-----------------------------SSQRSVARMDGDVIIGALFSVHHQPPAEKVP
ERK------------CGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWH
SSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQV
QNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVH
TEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAG-EKSFDRLLRKLRERLPKARVVVCF
CEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEAN--------GGITIKL
QSPEVRSFDDYFLKLR-----LDTNTRNPW-----FPEFWQHRF----QCRLPGHLLENP
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1EWK_secondry
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------------------------HHHHHHHHHHHHHHH---------------------
HHHHHHHHHHHH-----------------------------------------HHHHHHH
HHHH--------------------------------HHHHHHHHHHHHHH----------
---HHHHHHHHHHHHHHHHH-----------------HHHHHHHHHHHHH----------
---HHHHHHHHHHHHHH-----------------HHHH---HHHH---------------
------HHHHHHH-----------------------HHHHHHHH----------------
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----------------------HHHHHHHHHHHHHHHHHHHHHHH--------------H
HHHHHHHHHHHHHHHHHHHH------------HHHHHHHHHHHHHHHHHHHHHHHH----
--------------HHHHHHHHHHHHHHHHHHHHH----------------------HHH
HHHHHHHHHHHHHHHHHHHHHH-------------HHHHHHHHHHHHHHHHHHHHHH---
-------HHHHHHHHHHHHHHHHHHHHHHHHH-----------------------
;
omega +
---------------------------------------------------------X-X
------------X--X--------------------------------------------
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--------------------------------------X---------------X-----
-----------------X------------------------X-----------------
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----------X----------------------------X--------------------
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;no comment
Mm_V2R1b
---MKLLIAFSPLIVLIFFQEQISCFYLAKSASSGYYQDGDFVIGGLFSLRMTLGGHLKP
KILFKDKTDTLDVVHVDLTRH---YQHILAIVFAIENINKDPHILFNMSLGFYLFNVNFI
ETKAMESSMGLL-----------SGESPPIPN-YTCRPEKTDKLVA-VIGGISTSISTQI
SRVLSLYNIPQISYAPFDQSLGTSVQLQSPYQFPVHNVALYQGIIQLLLYFTWVWVGLVV
PDDMRGELFLRDITEEMTNHGLCVAFAEKVTEFS---ATKSVNLKHFMERVTLTGVI---
---VAFGDTHDFLISVYLSIYYAPFGNIWITTSDWYIT-LPIEQNRVYRHFG-GGLLFSF
HMDEILGFKDFLRSVQPRKYPHDIFIQDVWSILFECPYFDKDGVRELSQCEPNGSLSTRP
LHAWDMNTSPSSYKVHAAVYAIAQALHEELSLRVEGDSLDKSVLRPPLPWKLHPFLQNSQ
LGRSSNEKNVVNKEVSATKLDIFNYQSLQSGTKAQVKVGEFVFESHSVQHLSLNDKLITW
GEHHNQSPLSACSQSCPLGFRKTSVEGKPFCCFDCAPCPDGEIANETDMDQCIKCPEDQY
PNKQRNQCLPKIMVFLSHEDTLGAVLVSLAISLSAFSAMILGLFVCYRDTSIVRANNRNL
SYLLLISLMFCFFCSLIFIGQPSTVTCVLRQMIFGVVFSVAVSAILAKTFIVVVAFKAIK
PGSRLQMWMVMRLSNVIVCCGSIIQVCICAVWLGTYPPFPDVDMHSEFGHIILCCNEGST
LAFYCVLGYLGFLASLSLLIAFLVRRLPDSFNEAKTITFSMLVFCSVWISFIPTYLSSTG
KTMVAVEIFSILASSAGLLGCMFLPKCYVILLRSADLSRKKFFK-----------
;no comment
Rn_V2R1b
---MKLLIAFSLLILLTAFQEQISCFSLSKPASPGYYQDGDFVIGGLFSLRVTAGDTRSK
-FGFTDTTHIPEHVYVDFTKH---YQHMLAMVFAIENINKDPNILFNMSLGFYLFNVDFI
EMKAVESSMALL-----------SGESPAVPN-YSCRPEKTDKLVA-VIGGISTGISTQI
SQLLSLYNVPQISYAPFDQSFETKVQLQSPYQFPVHTTALYQGIIQLLLYFSWVWVGLVV
PDDVRGELFLRDITEEMNNHGLCVAFAEKFPEFP---AKDTGNREHFMERFTLTRVI---
---VAFGDTYSLLRFVYIIFCNTPFGNVWVTTSDWDITTLPFQQNLGYTYFG-GGLSFSV
HMDEILGFKNFLRSVQPRKYPQDIFIQDVWSILFECPYFDQHWIRELSQCEQNGNLSTRP
LHFWDMNTSPSSYKVHEAVYAIAQALHEELLLTLEGDSLHKDLPQAPLPWKLHPFLQKGQ
LRRSSNEENVVNKEVSATKLDIFNYQSLQNGSKAQVKVGEFVFESHSVQHFSLNEELITF
GEHHSQTPFSVCSPSCPLGFRKSPVEGKPFCCFDCLPCPDGEIANETDMDQCIKCPEDQY
PNRQRNQCLPKITEFLSHEDTLGAVFVSIAISLSALSAMILGLFICYRDTSIVRANNRNL
SYLLLVSLMLCFFCSLIFIGQPRTVTCVLRQMIFGIVFSVAVSTILAKTFIVVVAFKAIK
PGSALKMSMVIRLSNTIVFCGSIIQVCICAVWLGTYPPFPDVDMHSEFGQIILWCNEGST
LAFYCVLGYLGFLASLSLLIAFLARRLPDSFNETKTITFSMLVFCSVWISFVPTYLSSKG
KTMVAVEILSILASSAGLLGCIFLPKCYMILMSSGGHSRIKFFK-----------
;no comment
Rn_V2R1e
---MKLFIAFSLLIVPIVFQKQI-CLALSIPASPGYYQDGDFVIGGLFSLRVTSGDTKSK
-FGFKDTIYIPDIIYADFTKH---YQHILAMVFAIEKINKDLNILFNMSLGFYLFNVDFI
EMKAVESSMALL-----------SGESPPVPN-YSCRPEKTDKLVA-VIGGISTGISTQI
SRVLSLYNVPQISYAPFDQSLGTGVQLQSPYQFPVHTTALYQGIIQLLLYFSWVWVGLVV
PDDVRGELFLRDITEEMNNHGLCVAFAEKVPEFP---AKDTVNRGLFIERFTLTRVI---
---VAFGDTYSLLRFAYNIFCNTPFGNVWITTSDWDITTLSFRQNLSYTYFG-GELSFSV
HTDEILGFKDFLRSVQPRKYPQDIFIQDVWSILFECPYTYLYGIRELSQCEQNGNLSTRL
LYVWDMNTSPSSYKIHDAVYAIAQALHEELSFKLEENSLNKDVSKAPHLWKLHPFLQNGQ
LGRSTNEEAVMNKEVSATKLDIFNYQSLQSGTKAQVKVGEFVFESYSVQNFSLNDKLITW
GEHHNQTPFSVCSQSCPLGFRKTPVEGKPFCCFDCLLCPDGEIANETDMDQCIKCPEDQY
PNTQRNQCLPKITDFLSHEDTLGAVLVFVALSFSAFSAMILRLFICYRDTPIVRANNRNL
SYLLLVSLMLCFFCSLIFIGQPKTVTCVLRQVIFGVVFSVAVSTILAKTFIVVVAFKAIK
PGSALKMSMVIRLSNTIVFCGSIIQVCICAVWLGTYPPFPDVDMHSEFGQIILWCNEGST
FAFYCVLGYLGFLASLSLLIAFLARRLPDSFNEAKTITFSMLVFFSVWISFVPTYLSSKG
KTMVAVEILSILASSAGLLGCIFLPKCYVILMKSGDHSRKKFFK-----------
;no comment
Rn_V2R1c
MKLLIVLIAFSLLIVLIVFQEQISCFSLTKPASPGYYQDGDFVIGGIFSLRVTAGDTRSR
-FGFKDTIYIPEYVYVDLTKH---YQHILAMVFAIEKINKDTNILFNMSLGFYLFNVDFI
DMKAVESSMALL-----------SGQTPPVPN-YSCRPEKTDKLVA-VIGGISTGISTRI
SQVLSLYNVPQISYAPFDQSLGTGVQLQSPYQFPVYTTALYQGIIQLLLYFTWVWVGLVV
PDDVRGELFLRDITEEMNNHGLCVAFAEKVPEFP---AKDTVDRELFMERFTLTHVI---
---VAFGDTYSLLRFVYNIFCNTPFGNVWITTSDWDITTLPFQQNLGYTYFG-GGLSFSV
HMDEILGFKDFLRRVQPRKYPQDIFIQDVWSNLFECPYLDKDWIRELSQCEQNGNLSTRP
LHLWDMNTSPSSYKIHAAVYAIAQALHEELSLIVEGDLLNKGVPRAPLPWKLHPFLQNGQ
LGRSTNEETVVNKEVSATKLDIFNYQSLQSSTKAQVKVGEFVFESHSVQHFSLNDELITW
GEHHSQTPFAVCSQSCMLGFRKTPVEGKPFCCFDCLPCPDGEIANETDMDQCIKCPEDQY
PNKQRNQCLPKITAFLSHEDTLGAVFISLAISFSAFSAMILGLFICYRDTPIVRANNRNL
SYLLLVSLMLCFFCSLIFIGQPRTVTCVLRQTIFGVVFSIAISAILAKTFIVVVAFKAIK
PGSTLQTWMVTRVSNAIVCCGSSIQVCICAVWLGTYPPFPDVDMQSEFGQIILWCNEGST
LAFYCVLGYLGFLASLSLLIAFLARRLPDTFNEAKTITFSMLVFCSVWISFVPAYLSSKG
KNVVAVEILAILASSAGLLGCIFLPKCFVILLRSDDLPRKKFFK-----------
;no comment
Rn_V2R1d
---MKLLIAFSLLIVLIVFQEQISWFSLSIPASPGYYQDGDFVIGGLFSLRVTAGDTKSK
-FGFKDTISMPDIVYADFTKH---YQHMLAMVFAIENINKDPNILFNMSLGFYLFNVDFI
EMKAVESSMALL-----------SGETPPVPN-YSCRPEKTDKLVA-VIGGISTGISTQI
SRVLSLYNVPQISYAPFDQSLGTEVQLQSPYQFPVHTTALYQGIIQLLLYFTWIWVGLVV
PDDVRGELFLRDITEEMNNHGLCVAFAEKVPEFP---ARDTINRKLFMERFILTRVI---
---VAFGDTYSLLRFVYNIYCNTPFGNIWITTSDWDITTLPFQQNLGYTYFG-GGLSFSV
HTDEILEFKDFLRSVQPRKYPQDIFIQDVWSNLFECPYLDKDWIRELSQCEQNGNLSTRP
LYLWDMNTSPSSYKVHFAVYAIAEALHEELSLTVEGDSLRKGGPRALLPWKLHPFLQKCQ
LGRSSNEQNVMNNEVSATKLDIFNYQSLQSGTKAQVKVGKFVYESHSVQHFSLNDKIIMW
GEHHNHTPFSVCSQSCPLGFRKSPIEGKPFCCFDCLPCPDGEIANETDMDQCIKCPEDQY
PNKQRNWCHPKITAFLSHEDTLGAVLVSVAISLSVFSAMILGLFICYRDTPIVRANNRNL
SYLLLVSLMLCFFCSLIFIGQPRTVTCVLRQTIFGVVFSIAISAILAKTFIVVVAFKAIK
PGSTLQTWMVTRVSNAIVCCGSIIQVCICAVWLGTYPPFPDVDMHSEFGQIILWCNEGST
LAFYCVLGYLGFLASLSLLIAFLARRLPDTFNEAKTITFSMLVFCSVWISFVPAYLSSKG
KTMVAVEILTILASSAGLLGCIFLPKCFVILLKSGGLPRKKFSI-----------
;no comment
Mm_V2R1a
---MKLLIAFSLLIVLIIFQEQISCFSLNIPASPGYYQDGDFVIGGLFSLRVTAGDTRSR
-FGFTDTIHIPEYVYGDLTKH---YQHMLAMVFAIEKINKDPNILFNMTLGFSLFNVDFI
EMKAVESSVSLL-----------SGESPPIPN-YSCRPEKTDKLVA-VIGGISTGISTQI
SQILSLYNVPQISYAPFDHSLGTRVQLQSPYQFPVHTTALYQGIIQLLLYFTWVWVGLVV
PDDMRGELFLRDITEEMTNHGLCVAFAEKVPEFP---AKDTVNRELFMERFTLTHVI---
---VAFGDTYSLLRFVYNIFCNTPFGNIWITTSDWDITTLSFQQNLGYTYFG-GGLSFFV
HMDEILGFKDFLRDVQPRKYPHDIFIQDVWSILFECPYFEQHGIRELSQCEQNGSLSTRP
LHVWDMNTSPMSYKVHAAVYAIAQALHEELSLRVEGGSLHK----APLPWKLHPFLQKGQ
LRRNTN-EASMNKEVWTTELDIFNYQSLQSGTKAQVKVGEFVFGSHSVQHLSLNDKLITW
GEHHSQTPLSVCSQSCPFGYRKTPIEGKPFCCYDCIPCPDGEIANETDMDQCIKCPEDQY
PNKQRNQCLPKIMAFLSHEDTLGALLVCTAISLSAFAAMILGLFIHYRDTPIVRANNRNL
SYLLLVSLMLCFFCSLIFIGQPGTVTCVLRQMIFGVVFSIAVSAILAKTFIVVVAFKSIK
PRSTLQMWIVTRLSITIVCCGSIIQVCICAVWLGTYPPFPDVDMHSEFGHIILCCNEGST
LAFYCVLGYLGFLASLSLLIAFVRR-LPDSFNEAKTITFSMLVFCSVWISFIPTYLSSTG
KTMVAVEIFCILASSAGLLGCMFLPKCYVILLRSGDHSRKKVFK-----------
;no comment
Rn_V2R1a
---MKLLIVFSLLIVLIVFQVQISYVSLNNPASPGYYQDGDFVIGGLFSLRMTTGDTRSK
LFDFKDAIYLPEYVYGYLTKH---YQHMLAMIFAIEKINKDPNILFNMSLGFYLFNVDFI
EKKAIESSMALL-----------SGESPPVPN-YSCRPEKTDKLVA-VIGGISTGISTQI
SRVLSLYNIPQISYAPFDHSLGTRVQLQSPYQFPMHTTALYHGIIQLLLYFTWVWVGMVV
TDDMRGELFLRDITEEMNNHGLCVAFVEKIPEFS---AQDRVTKKAFMERYTSTRVI---
---VGFGDTYSLLRFVSSIIFHTNFGNVWITTSYWDFTILPFYQFISRALFSVGRLSFSV
RMDQILGFKDFLRSVQPRKYPHDIFLQDVWSILFKCPYSYQHGVRILTQCEQNGTLSTRP
LHVWDMNTLPPSYKVHAAVYAIAQALHEELSLGMEGDSFTKCVPQTHLPWKLHPFLQKGK
LWRRTNQENIINKEVLATVFDIFNSQSLQKGNEVQVQVGEFVFESHSVQHFSLNEKLITW
PRNQKEIPLSLCSQSCPLGFRKTPVEGKPSCCFDCLPCPDGEIANETDMDQCIKCPEDQY
PNKQRNQCLPKITAFLSCEDPLGAVLVSVAISLSAFSAMILGLFIHYRDTPIVRANNRNL
SYLLLVSLMLCFFCSLIFICQPTTVTCILRQMIFGVVFSITISAILAKTFIVVVAFKVIK
PGSTLQTWMVTRVSNAIVCCGSSIQVCICAVWLGTYPPFPDVDMQSEFGQIILWCNEGST
LAFYCVLGYLGFLASLSLLIAFLARRLPDTFNEAKTITFSMLVFCSVWISFVPTYLSSKG
KTMVAVEILSILASSSTLLGCIFLPKCYVILMRSGGHSRKKIFK-----------
;no comment
Mm_V2R1d
---MKLLIAFSLVIVLIVFQEKMFCFYISIPASSGYYQDGDFVIGGFFSLRVTDREDRTE
-FCFNETMNMTYGSYFNLPKH---YQHILAMVFAVETINKDPNILFNMSLGFYLFDVDFI
VMKAMESCMVLI-----------SGERPPIPN-YSCRPEKTNKPVA-VIGGYSKAITAQI
SQVLSLYNVPQISYAPFDQSLASRVQLQSPYQFPVHTAALYQGIIQLMLYFTWVWVGLVV
PDDMRGELYITELTEDMTKHGLCIAFAVRSPIFP---CRNTVNLIILEEELGSLDVV---
---LVYGDSYDFFWIVLYIPFLPFNGNVLITNSDWYTT-FPYFHNQVYEYFG-GVLLFSD
HMDEILGFKEFLRNLQPRKYPQNIFIQDMWSIVFECPHLYLHKVRELSQCEPNGSLSTRP
LHVWDMNTSPMSYKVHAAVYAIAQALHVELSVRVEGDSFDKGVLRAPLPWKLHPFLQNGQ
FVRLSNEENIVNKEGSATKLDIFNYQSLQSGTEGHVKVGEFVFEPHRVQHLSLNEELIRW
GEYHNMSALHVCSQTCPLGFSKIPDDWRPLCCYDCAPCPDGEFANETGASLPFGIP--QY
PNKQRNQCLPKITAFLSHEDTLGAVLGSMAISFAAFSAMILGLFIHYRDTPIVRANNRNL
SYLLLVSLKLCFFCSLMFIGEPRRVTCLLRQMIFGVVFSVALSAVLAKTFIVVVAFKVIK
PGSTLQMRMATQISNAIVCCGSIIQVCICAVWLGTYPPFPDVDMHSEFGQIILWYNEGST
LAFYCVLGYLGFLASLSLFIAFLVRSLPDSFNEAKTITFSMLVFCSVWISFVFTYLRSKA
KTMVAVEIVSILASSAGLLSFIFLPKCYVILLRSGGYSRKKFFK-----------
;no comment
Mm_V2R1c
---MKLLTAFSPLVVLILFQEQISCYYLTKYASSGYYQDADFVIGGLFSLRVTDGDTFIS
RSGVEDTSHIAEYVFADLIKY---YQHILAMVFAIEKINKDPNILFNKSLGFFLFNVNFI
EMKAAEGSMALL-----------SGESPPIPN-YSCRPEKTDKLVA-VIGGISTSISIQI
SRVLSLYNVPQISYAPFDQILGTRVQLQSPYQFSMHTAALYQGIVQLLLYFTWIWVGLVV
PDDMRGELYLRDITKEMISHGICFAFAEKVTEYS---SMDTVNWKHFMERLTLTPVI---
---ITVGDTHSLLRIVYFVIFYNLSGNVWITTSDWYITTLPFEQNLIYTHFG-GGLSFSF
HMDEILGFKDFLRSVQPRKYPHDIFIRHVWSSLFGCPHYYQHRLWDLSQCEPNGSLSTRP
LHAWDMNTSPYSYKVYAAVYAIAQALHEELSLRVEGDSSNKCLLQAPLPWKLHPFLQKGQ
LGRSTNEENTVNKEVSAIKLDIFNYQSLQSGTEAHVKVGEFVFDSHSVQHLSLNDKIITW
GKHRSQTPLSVCSQSCPFGFSKTAVEGKPFCCFDCVPCPDGEIANKTDMDQCIKCPEDQY
PNKQRNQCLPKIMVFLAHEDPLGTVLVSLAISLSAFSAMILGLFICYRETPIVRANNRNL
SYLLLISLKLCFSCSLMFIGQPRTVTCVLRQIIFGIVFSIVISAILAKTFIVVMAFKAIK
PGSILKMGMVTRLSNAIVCCGSIIQVCICAVWLGTYPPFPDVDMHSEFGQIILWCNEGST
LAFYCVLGYLGFLASLSLLIAFLARRLPDSFNEAKTITFSMLVFCSVWISFVPAYLSSKG
KTMVAVEILSILASSAGLLGCIFLPKCYVILLKSGGHSRKKFFK-----------