# Martin Taylor, Chris Ponting and Richard Copley # Supplemental table S1 - Frequency of 3 letter words adjacent to indels # # Semi-colons delimit the fields: # 1. Word (i.e. the 3 letter word that is counted) # 2. Results of all indel events # 3. Results of all insertions # 4. Results of all deletions # 5. Results of all slippage-like events # 6. Results of all Non-slippage-like events #### # Within each of the fields 2 - 6 the numbers represent: # : (,

); # Where mean_count and standard_deviation are from 1,000 simulated # datasets. P represents the Dunn-Sidak-corrected p-value (Null # hypothesis is that the observed_count is not an outlier in the # distribution of simulated counts). ####################################################################### TTA; 7:25.45 (5.07,0.02); 2:10.80 (3.32,0.41); 5:14.66 (3.93,0.59); 1:8.95 (3.03,0.43); 3:8.60 (2.96,0.98) TTT; 14:48.67 (6.84,2.57e-5); 3:20.87 (4.36,2.71e-3); 11:27.80 (5.25,0.08); 4:16.88 (4.00,0.08); 4:16.49 (3.94,0.09) TAT; 11:32.81 (5.72,8.84e-3); 7:13.81 (3.65,0.98); 4:19.00 (4.49,0.05); 2:11.49 (3.36,0.26); 6:11.08 (3.35,1.00) ATT; 14:40.80 (6.39,1.73e-3); 5:17.12 (4.11,0.18); 9:23.68 (4.98,0.19); 4:14.24 (3.76,0.34); 3:13.85 (3.71,0.20) TTG; 21:47.01 (7.02,0.01); 7:19.94 (4.72,0.33); 14:27.07 (5.21,0.54); 3:16.32 (4.14,0.08); 13:15.96 (4.17,1.00) TAC; 20:37.45 (6.16,0.26); 11:15.96 (3.90,1.00); 9:21.49 (4.73,0.41); 9:13.16 (3.74,1.00); 3:12.75 (3.51,0.30) TGC; 35:62.79 (7.75,0.02); 16:26.96 (5.13,0.88); 19:35.83 (5.90,0.24); 9:22.03 (4.74,0.32); 14:21.19 (4.46,1.00) ATG; 36:62.53 (7.59,0.03); 12:26.75 (5.04,0.20); 24:35.78 (5.84,0.94); 9:21.70 (4.60,0.31); 16:21.42 (4.63,1.00) GCG; 41:24.17 (5.00,0.05); 27:10.33 (3.32,3.25e-5); 14:13.84 (3.67,1.00); 15:8.42 (3.08,0.88); 14:8.14 (2.87,0.93) CAT; 34:57.49 (7.46,0.10); 15:24.62 (4.99,0.97); 19:32.87 (5.80,0.66); 13:20.21 (4.41,1.00); 13:19.33 (4.46,1.00) CGG; 54:32.26 (5.51,5.00e-3); 33:13.50 (3.68,7.41e-6); 21:18.76 (4.14,1.00); 21:11.23 (3.31,0.18); 18:10.91 (3.14,0.79) ATA; 15:24.22 (4.94,0.98); 5:10.22 (3.16,1.00); 10:14.00 (3.73,1.00); 6:8.50 (2.80,1.00); 5:8.18 (2.91,1.00) AGC; 112:71.53 (8.35,8.00e-5); 62:30.72 (5.48,7.40e-7); 50:40.81 (6.26,1.00); 54:25.23 (4.98,4.88e-7); 37:23.88 (4.96,0.41) AGA; 127:82.37 (8.88,3.24e-5); 45:35.07 (5.90,1.00); 82:47.30 (6.77,1.87e-5); 53:28.81 (5.20,2.13e-4); 36:27.90 (5.19,1.00) AGG; 102:67.41 (7.97,9.08e-4); 43:28.80 (5.33,0.39); 59:38.62 (6.23,0.07); 40:23.46 (4.55,0.02); 29:22.75 (4.75,1.00) GTT; 24:35.97 (5.95,0.95); 7:15.20 (3.85,0.88); 17:20.77 (4.53,1.00); 6:12.62 (3.56,0.98); 9:12.15 (3.39,1.00) AAT; 28:41.52 (6.58,0.93); 9:17.54 (4.16,0.93); 19:23.99 (4.92,1.00); 10:14.54 (3.87,1.00); 12:14.03 (3.69,1.00) ATC; 34:49.31 (7.13,0.87); 12:21.14 (4.72,0.97); 22:28.17 (5.34,1.00); 13:17.33 (4.24,1.00); 9:16.63 (4.12,0.99) GAG; 127:88.01 (9.34,1.90e-3); 58:37.74 (6.07,0.05); 69:50.26 (6.89,0.34); 49:30.76 (5.57,0.07); 30:29.69 (5.35,1.00) CAG; 150:104.74 (9.79,2.41e-4); 66:44.75 (6.60,0.08); 84:59.99 (7.60,0.10); 56:36.64 (5.96,0.07); 56:35.52 (5.84,0.03) TGA; 43:61.45 (7.74,0.67); 16:26.52 (5.18,0.94); 27:34.93 (5.86,1.00); 8:21.57 (4.47,0.14); 20:20.83 (4.61,1.00) CCA; 107:81.00 (9.13,0.25); 50:34.59 (5.81,0.40); 57:46.41 (6.88,1.00); 26:28.43 (5.34,1.00); 40:27.30 (5.08,0.55) CTC; 84:63.61 (7.83,0.45); 27:27.16 (5.14,1.00); 57:36.44 (6.07,0.04); 32:22.41 (4.57,0.90); 30:21.48 (4.72,0.99) GCA; 86:65.34 (7.74,0.39); 44:28.23 (5.44,0.22); 42:37.11 (5.85,1.00); 40:23.12 (4.77,0.03); 19:21.84 (4.68,1.00) TTC; 42:55.00 (7.10,0.99); 11:23.43 (4.71,0.41); 31:31.57 (5.47,1.00); 11:19.35 (4.35,0.97); 16:18.43 (4.10,1.00) TCT; 46:59.88 (7.65,0.99); 12:25.51 (5.05,0.38); 34:34.37 (6.06,1.00); 16:20.91 (4.35,1.00); 11:20.26 (4.52,0.93) CCG; 40:30.86 (5.61,1.00); 22:12.94 (3.66,0.57); 18:17.92 (4.36,1.00); 13:10.47 (3.18,1.00); 14:10.65 (3.38,1.00) ACA; 80:61.77 (7.92,0.75); 24:26.43 (5.32,1.00); 56:35.34 (5.75,0.02); 32:21.41 (4.55,0.72); 26:21.12 (4.59,1.00) TGG; 64:82.52 (9.05,0.93); 23:35.47 (5.81,0.87); 41:47.05 (6.80,1.00); 22:29.03 (5.33,1.00); 29:27.67 (5.20,1.00) AAA; 53:67.53 (8.22,0.99); 11:28.41 (5.49,0.09); 42:39.12 (6.10,1.00); 14:23.46 (4.88,0.97); 20:23.16 (4.98,1.00) CTA; 27:34.39 (5.68,1.00); 12:14.53 (3.78,1.00); 15:19.86 (4.39,1.00); 12:12.13 (3.40,1.00); 10:11.60 (3.44,1.00) AAG; 106:83.94 (8.91,0.57); 36:35.63 (5.72,1.00); 70:48.31 (6.79,0.09); 48:29.37 (5.22,0.02); 28:28.55 (5.40,1.00) ACT; 39:49.15 (6.89,1.00); 18:20.78 (4.58,1.00); 21:28.37 (5.35,1.00); 11:17.01 (3.97,1.00); 14:16.81 (4.08,1.00) TCG; 16:19.99 (4.54,1.00); 12:8.52 (2.90,1.00); 4:11.47 (3.40,0.84); 3:6.88 (2.74,1.00); 6:6.87 (2.69,1.00) CCC; 81:65.12 (7.87,0.94); 36:27.91 (5.24,1.00); 45:37.21 (6.05,1.00); 26:22.59 (4.69,1.00); 29:22.17 (4.72,1.00) GCC; 89:71.99 (8.62,0.96); 45:30.85 (5.57,0.51); 44:41.14 (6.44,1.00); 30:25.23 (5.15,1.00); 33:24.23 (5.01,1.00) CGA; 33:27.21 (5.21,1.00); 16:11.15 (3.33,1.00); 17:16.05 (4.01,1.00); 9:9.41 (3.05,1.00); 13:9.36 (3.19,1.00) CTT; 48:58.16 (7.62,1.00); 17:24.88 (4.92,1.00); 31:33.28 (5.73,1.00); 20:20.26 (4.44,1.00); 16:19.74 (4.61,1.00) CGC; 32:26.48 (5.24,1.00); 23:11.09 (3.42,0.03); 9:15.40 (3.93,1.00); 17:9.25 (3.10,0.55); 5:9.06 (3.10,1.00) TAA; 25:20.78 (4.57,1.00); 14:8.62 (2.89,0.98); 11:12.16 (3.54,1.00); 10:7.22 (2.65,1.00); 8:7.05 (2.69,1.00) CCT; 95:79.77 (8.76,1.00); 38:34.30 (5.87,1.00); 57:45.47 (6.80,1.00); 39:28.09 (5.30,0.92); 28:26.92 (5.26,1.00) GGT; 41:48.38 (7.16,1.00); 22:20.91 (4.64,1.00); 19:27.47 (5.45,1.00); 12:16.84 (4.34,1.00); 15:16.32 (4.01,1.00) GAT; 49:57.36 (7.56,1.00); 25:24.50 (4.92,1.00); 24:32.85 (5.70,1.00); 12:20.24 (4.55,0.99); 20:19.13 (4.42,1.00) GAA; 100:85.65 (9.30,1.00); 41:36.58 (5.98,1.00); 59:49.07 (7.03,1.00); 36:30.15 (5.33,1.00); 36:28.66 (5.51,1.00) TCC; 52:60.41 (7.60,1.00); 19:25.88 (5.11,1.00); 33:34.54 (5.75,1.00); 19:21.07 (4.49,1.00); 18:20.25 (4.52,1.00) TGT; 48:55.31 (7.37,1.00); 22:23.70 (4.87,1.00); 26:31.60 (5.62,1.00); 18:19.62 (4.58,1.00); 14:18.56 (4.43,1.00) GCT; 65:74.66 (8.43,1.00); 26:32.45 (5.60,1.00); 39:42.20 (6.32,1.00); 20:26.18 (5.00,1.00); 24:25.07 (4.90,1.00) CTG; 93:102.42 (9.88,1.00); 42:44.21 (6.56,1.00); 51:58.21 (7.40,1.00); 24:35.79 (5.89,0.95); 32:34.53 (5.80,1.00) GGC; 59:64.60 (8.03,1.00); 27:27.65 (5.18,1.00); 32:36.94 (6.22,1.00); 22:22.31 (4.68,1.00); 20:22.06 (4.74,1.00) CGT; 19:20.60 (4.77,1.00); 8:8.43 (3.00,1.00); 11:12.17 (3.64,1.00); 8:7.18 (2.73,1.00); 4:6.96 (2.64,1.00) ACG; 23:21.23 (4.62,1.00); 10:8.86 (3.01,1.00); 13:12.37 (3.59,1.00); 7:7.14 (2.60,1.00); 6:7.35 (2.70,1.00) ACC; 53:56.70 (7.46,1.00); 30:24.07 (4.87,1.00); 23:32.63 (5.82,1.00); 15:19.69 (4.49,1.00); 21:19.26 (4.51,1.00) CAC; 56:59.53 (7.76,1.00); 25:25.51 (5.08,1.00); 31:34.01 (5.67,1.00); 20:20.76 (4.62,1.00); 17:20.09 (4.54,1.00) GTC; 44:41.70 (6.11,1.00); 18:17.77 (4.14,1.00); 26:23.93 (4.87,1.00); 15:14.48 (3.79,1.00); 19:14.26 (3.71,1.00) CAA; 61:64.20 (7.85,1.00); 24:27.55 (5.08,1.00); 37:36.65 (6.08,1.00); 28:22.53 (4.67,1.00); 19:21.56 (4.49,1.00) GTG; 74:70.62 (8.28,1.00); 36:30.13 (5.42,1.00); 38:40.49 (6.29,1.00); 27:24.65 (4.90,1.00); 21:24.02 (4.76,1.00) GAC; 65:62.18 (7.65,1.00); 31:26.42 (5.20,1.00); 34:35.76 (5.76,1.00); 21:21.53 (4.67,1.00); 19:21.31 (4.60,1.00) GGG; 56:53.69 (7.17,1.00); 30:22.71 (4.75,1.00); 26:30.97 (5.58,1.00); 16:18.47 (4.31,1.00); 18:18.31 (4.36,1.00) AAC; 52:49.94 (6.88,1.00); 21:21.09 (4.61,1.00); 31:28.85 (5.32,1.00); 19:17.55 (4.11,1.00); 12:17.03 (3.95,1.00) TCA; 60:58.94 (7.91,1.00); 19:24.88 (4.86,1.00); 41:34.07 (6.04,1.00); 13:20.64 (4.64,1.00); 23:19.93 (4.49,1.00) TAG; 17:17.21 (4.22,1.00); 5:7.01 (2.62,1.00); 12:10.19 (3.29,1.00); 4:5.78 (2.41,1.00); 6:5.99 (2.42,1.00) GGA; 80:80.87 (9.02,1.00); 31:34.41 (5.85,1.00); 49:46.47 (6.83,1.00); 26:28.28 (5.40,1.00); 30:27.51 (5.26,1.00) AGT; 49:49.43 (6.93,1.00); 13:20.84 (4.51,1.00); 36:28.59 (5.31,1.00); 15:17.23 (4.12,1.00); 22:16.68 (4.07,1.00) GTA; 28:27.93 (5.30,1.00); 9:11.66 (3.48,1.00); 19:16.26 (4.02,1.00); 5:9.72 (3.13,1.00); 19:9.61 (3.06,0.13)