TY  - JOUR
A1  - Blanc, Guillaume
A1  - Ogata, Hiroyuki
A1  - Robert, Catherine
A1  - Audic, Stéphane
A1  - Claverie, Jean-Michel
A1  - Raoult, Didier
T1  - Lateral gene transfer between obligate intracellular bacteria: Evidence from the Rickettsia massiliae genome
Y1  - 2007/11/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 000 
EP  - 000 
DO  - 10.1101/gr.6742107 
VL  - 17 
IS  - 11 
UR  - http://genome.cshlp.org/content/early/2007/10/04/gr.6742107.abstract 
N2  - Rickettsia massiliae is a tick-borne obligate intracellular α-proteobacteria causing spotted fever in humans. Here, we present the sequence of its genome, comprising a 1.3-Mb circular chromosome and a 15.3-kb plasmid. The chromosome exhibits long-range colinearity with the other Spotted Fever Group Rickettsia genomes, except for a large fragment specific to R. massiliae that contains 14 tra genes presumably involved in pilus formation and conjugal DNA transfer. We demonstrate that the tra region was acquired recently by lateral gene transfer (LGT) from a species related to Rickettsia bellii. Further analysis of the genomic sequences identifies additional candidates of LGT between Rickettsia. Our study indicates that recent LGT between obligate intracellular Rickettsia is more common than previously thought. 
ER  -