RT Journal A1 Elsik, Christine G. A1 Worley, Kim C. A1 Zhang, Lan A1 Milshina, Natalia V. A1 Jiang, Huaiyang A1 Reese, Justin T. A1 Childs, Kevin L. A1 Venkatraman, Anand A1 Dickens, C. Michael A1 Weinstock, George M. A1 Gibbs, Richard A. T1 Community annotation: Procedures, protocols, and supporting tools JF Genome Research JO Genome Research YR 2006 FD November 01 VO 16 IS 10 SP 000 OP 000 DO 10.1101/gr.5580606 UL http://genome.cshlp.org/content/early/2006/10/25/gr.5580606.abstract AB Investigators at the Baylor College of Medicine Human Genome Sequencing Center (BCM–HGSC) and BeeBase organized a community-wide effort to manually annotate the honey bee (Apis mellifera) genome. Although various strategies for manual annotation have been used in the past, the value of dispersed community annotation has not yet been demonstrated. Here we make a case for the merit of dispersed community annotation. We present annotation procedures, standard protocols, and tools used for sequence analysis, data submission, and data management. We also report lessons learned from this dispersed community annotation effort for a metazoan genome.