RT Journal
A1 Farahbod, Marjan
A1 Diab, Aboud
A1 Sud, Paul
A1 Kagda, Meenakshi S.
A1 Whaling, Ian
A1 Foroozandeh, Mehdi
A1 Goel, Ishan
A1 Daneshpajouh, Habib
A1 Hitz, Benjamin
A1 Cherry, J. Michael
A1 Libbrecht, Maxwell W.
T1 Integrative chromatin state annotation of 234 human ENCODE4 cell types using Segway
JF Genome Research 
JO Genome Research 
YR 2025 
FD October 06 
DO 10.1101/gr.280633.125 
SP gr.280633.125 
UL http://genome.cshlp.org/content/early/2025/10/06/gr.280633.125.abstract 
AB The fourth and final phase of the ENCODE consortium has newly profiled epigenetic activity in hundreds of human tissues. Chromatin state annotations created by segmentation and genome annotation (SAGA) methods such as Segway have emerged as the predominant integrative summary of such data sets. Here, we present the ENCODE4 Catalog of Segway Annotations, a set of sample-specific genome-wide chromatin state annotations of 234 human biosamples inferred from 1,794 genomics experiments. This catalog identifies genomic elements, accurately captures cell type-specific regulatory patterns, and facilitates discovery of elements involved in phenotype and disease.