TY  - JOUR
A1  - Reid, Adam James
A1  - Blake, Damer Peter
A1  - Ansari, Hifzur Rahman
A1  - Billington, Karen
A1  - Browne, Hilary P
A1  - Bryant, Josephine M
A1  - Dunn, Matthew
A1  - Hung, Stacy S
A1  - Kawahara, Fumiya
A1  - Miranda-Saavedra, Diego
A1  - Malas, Tareq
A1  - Mourier, Tobias
A1  - Naghra, Hardeep
A1  - Nair, Mridul
A1  - Otto, Thomas Dan
A1  - Rawlings, Neil David
A1  - Rivailler, Pierre
A1  - Sanchez-Flores, Alejandro
A1  - Sanders, Mandy
A1  - Subramaniam, Chandra
A1  - Tay, Yea-Ling
A1  - Woo, Yong
A1  - Wu, Xikun
A1  - Barrell, Bart
A1  - Dear, Paul H
A1  - Doerig, Christian
A1  - Gruber, Arthur
A1  - Ivens, Alasdair C
A1  - Parkinson, John
A1  - Rajandream, Marie-Adèle
A1  - Shirley, Martin William
A1  - Wan, Kiew-Lan
A1  - Berriman, Matthew
A1  - Tomley, Fiona M
A1  - Pain, Arnab
T1  - Genomic analysis of the causative agents of coccidiosis in domestic chickens
Y1  - 2014/07/11 
JF  - Genome Research 
JO  - Genome Research 
DO  - 10.1101/gr.168955.113 
SP  - gr.168955.113 
UR  - http://genome.cshlp.org/content/early/2014/07/11/gr.168955.113.abstract 
N2  - Global production of chickens has trebled in the past two decades and they are now the most important source of dietary animal protein worldwide.  Chickens are subject to many infectious diseases that reduce their performance and productivity. Coccidiosis, caused by apicomplexan protozoa of the genus Eimeria, is one of the most important poultry diseases. Understanding the biology of Eimeria parasites underpins development of new drugs and vaccines needed to improve global food security.  We have produced annotated genome sequences of all seven species of Eimeria that infect domestic chickens, which reveal the full extent of previously described repeat-rich and repeat-poor regions and show that these parasites possess the most repeat-rich proteomes ever described.  Furthermore, while no other apicomplexan has been found to possess retrotransposons, Eimeria is home to a family of chromoviruses. Analysis of Eimeria genes involved in basic biology and host-parasite interaction highlights adaptations to a relatively simple developmental life cycle and a complex array of co-expressed surface proteins involved in host cell binding. 
ER  -