RT Journal
A1 Earl, Dent
A1 Bradnam, Keith
A1 St. John, John
A1 Darling, Aaron
A1 Lin, Dawei
A1 Fass, Joseph
A1 Yu, Hung On Ken
A1 Buffalo, Vince
A1 Zerbino, Daniel R.
A1 Diekhans, Mark
A1 Nguyen, Ngan
A1 Ariyaratne, Pramila Nuwantha
A1 Sung, Wing-Kin
A1 Ning, Zemin
A1 Haimel, Matthias
A1 Simpson, Jared T.
A1 Fonseca, Nuno A.
A1 Birol, İnanç
A1 Docking, T. Roderick
A1 Ho, Isaac Y.
A1 Rokhsar, Daniel S.
A1 Chikhi, Rayan
A1 Lavenier, Dominique
A1 Chapuis, Guillaume
A1 Naquin, Delphine
A1 Maillet, Nicolas
A1 Schatz, Michael C.
A1 Kelley, David R.
A1 Phillippy, Adam M.
A1 Koren, Sergey
A1 Yang, Shiaw-Pyng
A1 Wu, Wei
A1 Chou, Wen-Chi
A1 Srivastava, Anuj
A1 Shaw, Timothy I.
A1 Ruby, J. Graham
A1 Skewes-Cox, Peter
A1 Betegon, Miguel
A1 Dimon, Michelle T.
A1 Solovyev, Victor
A1 Seledtsov, Igor
A1 Kosarev, Petr
A1 Vorobyev, Denis
A1 Ramirez-Gonzalez, Ricardo
A1 Leggett, Richard
A1 MacLean, Dan
A1 Xia, Fangfang
A1 Luo, Ruibang
A1 Li, Zhenyu
A1 Xie, Yinlong
A1 Liu, Binghang
A1 Gnerre, Sante
A1 MacCallum, Iain
A1 Przybylski, Dariusz
A1 Ribeiro, Filipe J.
A1 Yin, Shuangye
A1 Sharpe, Ted
A1 Hall, Giles
A1 Kersey, Paul J.
A1 Durbin, Richard
A1 Jackman, Shaun D.
A1 Chapman, Jarrod A.
A1 Huang, Xiaoqiu
A1 DeRisi, Joseph L.
A1 Caccamo, Mario
A1 Li, Yingrui
A1 Jaffe, David B.
A1 Green, Richard E.
A1 Haussler, David
A1 Korf, Ian
A1 Paten, Benedict
T1 Assemblathon 1: A competitive assessment of de novo short read assembly methods
JF Genome Research 
JO Genome Research 
YR 2011 
FD September 16 
DO 10.1101/gr.126599.111 
UL http://genome.cshlp.org/content/early/2011/11/02/gr.126599.111.abstract 
AB Low-cost short read sequencing technology has revolutionized genomics, though it is only just becoming practical for the high-quality de novo assembly of a novel large genome. We describe the Assemblathon 1 competition, which aimed to comprehensively assess the state of the art in de novo assembly methods when applied to current sequencing technologies. In a collaborative effort, teams were asked to assemble a simulated Illumina HiSeq data set of an unknown, simulated diploid genome. A total of 41 assemblies from 17 different groups were received. Novel haplotype aware assessments of coverage, contiguity, structure, base calling, and copy number were made. We establish that within this benchmark: (1) It is possible to assemble the genome to a high level of coverage and accuracy, and that (2) large differences exist between the assemblies, suggesting room for further improvements in current methods. The simulated benchmark, including the correct answer, the assemblies, and the code that was used to evaluate the assemblies is now public and freely available from http://www.assemblathon.org/.