TY  - JOUR
A1  - Marziali, Andre
A1  - Willis, Thomas D.
A1  - Federspiel, Nancy A.
A1  - Davis, Ronald W.
T1  - An Automated Sample Preparation System for Large-Scale DNA Sequencing
Y1  - 1999/05/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 457 
EP  - 462 
DO  - 10.1101/gr.9.5.457 
VL  - 9 
IS  - 5 
UR  - http://genome.cshlp.org/content/9/5/457.abstract 
N2  - Recent advances in DNA sequencing technologies, both in the form of high lane-density gels and automated capillary systems, will lead to an increased requirement for sample preparation systems that operate at low cost and high throughput. As part of the development of a fully automated sequencing system, we have developed an automated subsystem capable of producing 10,000 sequence-ready ssDNA templates per day from libraries of M13 plaques at a cost of $0.29 per sample. This Front End has been in high throughput operation since June, 1997 and has produced > 400,000 high-quality DNA templates. 
ER  -